Exhibit 25.1 POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Joseph Peterson, M.D. and Ronald W. Rudolph and each of them, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and re-substitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Report on Form 10-K, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities and Exchange Act of 1934, this report has been signed below by the following persons on behalf of the Registrant and in the capacities and on the dates indicated: Signature Title Date --------- ----- ---- /s/ Joseph Peterson, M.D. Chief Executive Officer, March 29, 2002 - --------------------------- Joseph Peterson, M.D. President and Director (Principal Executive Officer) /s/ Ronald W. Rudolph Executive Vice President, March 29, 2002 - --------------------------- Ronald W. Rudolph Finance and Chief Financial Officer (Principal Financial and Accounting Officer) /s/ Karen Brenner Director March 29, 2002 - --------------------------- Karen Brenner /s/ William E. Brock Director March 29, 2002 - --------------------------- William E. Brock /s/ Elliot Ettenberg Director March 29, 2002 - --------------------------- Elliot Ettenberg /s/ Jonathan S. Holman Director March 29, 2002 - --------------------------- Jonathan S. Holman /s/ Jeremy M. Jones Director March 29, 2002 - --------------------------- Jeremy M. Jones