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                                   EXHIBIT 5.1

                          OPINION OF COOLEY GODWARD LLP




May 13, 1997



Cerus Corporation
2525 Stanwell Drive, Suite 300
Concord, CA 94520

Ladies and Gentlemen:

You have requested our opinion with respect to certain matters in connection
with the filing by Cerus Corporation (the "Company") of a Registration Statement
on Form S-8 (the "Registration Statement") with the Securities and Exchange
Commission covering the offering of up to 1,174,950 shares of the Company's
Common Stock, $.0001 par value, (the "Shares") pursuant to its 1996 Equity
Incentive Plan and Employee Stock Purchase Plan (the "Plans").

In connection with this opinion, we have examined the Registration Statement and
related Prospectuses, your Amended and Restated Certificate of Incorporation and
Bylaws, as amended, and such other documents, records, certificates, memoranda
and other instruments as we deem necessary as a basis for this opinion. We have
assumed the genuineness and authenticity of all documents submitted to us as
originals, the conformity to originals of all documents submitted to us as
copies thereof, and the due execution and delivery of all documents where due
execution and delivery are a prerequisite to the effectiveness thereof.

On the basis of the foregoing, and in reliance thereon, we are of the opinion
that the Shares, when sold and issued in accordance with the Plans, the
Registration Statement and related Prospectuses, will be validly issued, fully
paid and nonassessable (except as to shares issued pursuant to certain deferred
payment arrangements, which will be fully paid and nonassessable when such
deferred payments are made in full).

We consent to the filing of this opinion as an exhibit to the Registration
Statement.

Very truly yours,

COOLEY GODWARD LLP

/s/ Howard G. Ervin
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Howard G. Ervin

HGE:wp




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