1 REGISTRATION NO. 33-9470 ================================================================================ SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 3 TO FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 AMGEN BOULDER INC. (Exact name of registrant as specified in its charter) (FORMERLY KNOWN AS SYNERGEN, INC.) DELAWARE 84-0868248 (State or other jurisdiction of (I.R.S. Employer incorporation or organization) Identification No.) C/O AMGEN INC., AMGEN CENTER, 1840 91320-1789 DEHAVILLAND DRIVE, THOUSAND OAKS, CA (Zip Code) (Address of Principal Executive Offices) SYNERGEN, INC. INCENTIVE AND NON-QUALIFIED STOCK OPTION PLAN (Full title of the plan) MARGARET VALEUR-JENSEN, PH.D. With copies to: SENIOR COUNSEL GEORGE A. VANDEMAN, ESQ. AMGEN INC. LATHAM & WATKINS AMGEN CENTER 633 WEST FIFTH STREET, SUITE 4000 1840 DEHAVILLAND DRIVE LOS ANGELES, CA 90071 THOUSAND OAKS, CA 91320-1789 (213) 485-1234 (Name and address of agent for service) (805) 447-1000 (Telephone number, including area code, of agent for service) ================================================================================ 2 This Registration Statement No. 33-9470 (the "Registration Statement") registered an aggregate of 459,667 shares of Common Stock, par value $.01 (the "Securities"), of Amgen Boulder Inc. (formerly known as Synergen, Inc.) (the "Registrant"). On December 29, 1994, the Registrant became a wholly-owned subsidiary of Amgen Inc. following a merger. As a result of the merger, it is anticipated that the Registrant's securities will no longer be registered under the Securities Act of 1934, as amended. Accordingly, the Registrant is removing the Securities from registration under the Securities Act of 1933, as amended. 2 3 SIGNATURE Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant has duly caused this Post-Effective Amendment No. 3 to the Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Thousand Oaks, State of California, on March 6, 1995. AMGEN BOULDER INC. By: /s/ THOMAS E. WORKMAN, JR. --------------------------------- Thomas E. Workman, Jr. Vice President, Secretary and General Counsel POWER OF ATTORNEY Each person whose signature appears below constitutes and appoints Thomas E. Workman, Jr. his true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to the Registration Statement amended by this Post-Effective Amendment No. 3, and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or any of them, or their or his substitutes or substitute, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities Act of 1933, as amended, this Post-Effective Amendment No. 3 to the Registration Statement has been signed by the following persons in the capacities and on the dates indicated. Signature Title Date - --------- ----- ---- /s/ GORDON M. BINDER - ----------------------- Gordon M. Binder Chief Executive Officer March 13, 1995 (Principal Executive Officer) /s/ ROBERT S. ATTIYEH - ----------------------- Robert S. Attiyeh Senior Vice President, Finance March 13, 1995 and Corporate Development and Director (Principal Financial and Accounting Officer) 3 4 /s/ THOMAS E. WORKMAN, JR. - --------------------------- Thomas E. Workman, Jr. Vice President, Secretary, March 6, 1995 General Counsel and Director /s/ DR. N. KIRBY ALTON - --------------------------- Dr. N. Kirby Alton Director March 13, 1995 /s/ DR. MICHAEL BEVILACQUA - ---------------------------- Dr. Michael Bevilacqua Director March 14, 1995 /s/ Dr. GEORGE MORSTYN - --------------------------- Dr. George Morstyn Director March 13, 1995 /s/ DR. DANIEL VAPNEK - --------------------------- Dr. Daniel Vapnek Director March 13, 1995 4