EXHIBIT 99(f)

                               SECURITY AGREEMENT

                                  April 2, 2003

THIS SECURITY AGREEMENT (this "SECURITY AGREEMENT") is made as of the date first
written above by and between Neoprobe Corporation, a Delaware corporation
qualified to do business in the State of Ohio, with principal offices located at
425 Metro Place North, Dublin, Ohio 43017 ("DEBTOR"), David C. Bupp a resident
of the State of Ohio ("BUPP"), and Donald E. Garlikov, a resident of the State
of Ohio ("GARLIKOV") (each of Bupp and Garlikov a "SECURED PARTY," and
collectively the "SECURED PARTIES").

         This Security Agreement is entered into with respect to a Senior
Secured Note in the principal amount of $250,000 (the "SENIOR NOTE") delivered
to Bupp (a) by Debtor pursuant to a 8.5% Senior Secured Note Purchase Agreement,
as the same may be amended, modified or supplemented from time to time in
accordance with the terms thereof (the "SENIOR PURCHASE AGREEMENT") dated the
same date as this Security Agreement, and (b) a 9.5% Secured Convertible Note of
even date herewith in the principal amount of $250,000 (the "CONVERTIBLE NOTE"
and collectively with the Senior Note, the "NOTES", and individually a "NOTE")
delivered to Garlikov by Debtor pursuant to a 9.5% Secured Note Convertible Note
Purchase Agreement, as the same may be amended, modified or supplemented from
time to time in accordance with the terms thereof (the "CONVERTIBLE PURCHASE
AGREEMENT", and collectively with the Senior Purchase Agreement, the "PURCHASE
AGREEMENTS" and individually a "PURCHASE AGREEMENT").

         Capitalized terms not otherwise defined herein shall have the
meaning(s) ascribed to them in the Purchase Agreement.

         Secured Party and Debtor agree as follows:

SECTION 1.        DEFINITIONS.

         1.1      "Collateral" means all of Debtor's chattel paper, deposit
                  accounts, documents, Equipment, General Intangibles, goods,
                  instruments, Intellectual Property, Inventory, letters of
                  credit, and all sums on deposit in any account,; together with
                  (a) all substitutions and replacements for and products of any
                  of the foregoing; (b) in the case of all goods, all
                  accessions; (c) all accessories, attachments, parts, equipment
                  and repairs now or hereafter attached or affixed to or used in
                  connection with any goods; (d) all warehouse receipts, bills
                  of lading and other documents of title now or hereafter
                  covering such goods; (e) all collateral subject to any lien
                  granted by Debtor to the Secured Party; (f) any money, or
                  other assets of Debtor that now or hereafter come into the
                  possession, custody, or control of the Secured Party; (g) all
                  books, records, ledger cards and other property pertaining to
                  any of the foregoing, and any equipment on which any such
                  items are stored or maintained; and (h) proceeds of any and
                  all of the foregoing; ; provided, however, that the Collateral
                  shall not include any accounts of Debtor, as such term is
                  defined in the UCC.



         1.2      "Equipment" means all of Debtor's equipment, as such term is
                  defined in the UCC, whether now owned or hereafter acquired,
                  including but not limited to all present and future machinery,
                  vehicles, furniture, fixtures, manufacturing equipment, shop
                  equipment, office and recordkeeping equipment, parts, tools,
                  supplies, and including specifically (without limitation) the
                  goods described in any equipment schedule or list herewith or
                  hereafter furnished to a Secured Party by Debtor, and whether
                  located on real estate owned or leased by Debtor or otherwise.

         1.3      "General Intangibles" means all of Debtor's general
                  intangibles, as such term is defined in the UCC, whether now
                  owned or hereafter acquired, including (without limitation)
                  all Intellectual Property, trade secrets, customer or supplier
                  lists and contracts, manuals, operating instructions, permits,
                  franchises, the right to use Debtor's name, and the goodwill
                  of Debtor's business.

         1.4      "Intellectual Property" means (a) trademarks, trademark
                  registrations, trade names and trademark applications for any
                  of the foregoing in the United States Patent and Trademark
                  Office or in any other office or with any other official
                  anywhere in the world or which are used in the United States
                  or any state, territory or possession thereof, or in any other
                  place, nation or jurisdiction anywhere in the world, and (i)
                  all renewals thereof, (ii) all income, royalties, damages and
                  payments now and hereafter due and/or payable with respect
                  thereto, including, without limitation, payments under all
                  licenses entered into in connection therewith and damages and
                  payments for past or future infringements thereof, (iii) the
                  right to sue for past, present and future infringements
                  thereof, and (iv) all rights corresponding thereto throughout
                  the world (all of the foregoing trademarks, and trademark
                  registrations, trade names, service marks, service mark
                  registration and applications, together with the items
                  described in clauses (i) through (iv in this subparagraph (a),
                  are sometimes hereinafter individually and/or collectively
                  referred to as the "TRADEMARKS"); (b) license agreements with
                  any other party in connection with any Trademarks or such
                  other party's trademarks or trademark applications, whether
                  Debtor is a licensor or licensee under any such license
                  agreement, and the right to prepare for sale, sell and
                  advertise for sale, all of the inventory now or hereafter
                  owned by Debtor and now or hereafter covered by such license
                  agreements (all of the foregoing being hereinafter referred to
                  collectively as the "LICENSES"); (c) the goodwill of Debtor's
                  business connected with and symbolized by the Trademarks, and
                  (d) patents and patent applications in the United States
                  Patent and Trademark Office or in any other office or with any
                  other official anywhere in the world or which are used in the
                  United States or any state, territory or possession thereof,
                  or in any other place, nation or jurisdiction anywhere in the
                  world, and (i) all renewals thereof, (ii) all income,
                  royalties, damages and payments now and hereafter due and/or
                  payable with respect thereto, including, without limitation,
                  payments under all licenses entered into in connection
                  therewith and damages and payments for past or future
                  infringements thereof, (iii) the right to sue for past,
                  present and future

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                  infringements thereof, and (iv) all rights corresponding
                  thereto throughout the world.

         1.5      "Inventory" means all raw materials, work in process, finished
                  goods and materials and supplies of any kind, nature or
                  description which are or might be used or consumed in the
                  business of Debtor or used in connection with the
                  manufacturing, packing, shipping, advertising, selling or
                  finishing of such goods, merchandise and other personal
                  property, and all goods, merchandise and other personal
                  property whenever located, to be furnished by the Debtor under
                  any contract or contract for service or held for sale or
                  lease, whether now owned or hereafter acquired, and all
                  documents of title or other documents representing the
                  foregoing.

         1.6      "Obligations." This Security Agreement secures the following:

                  (a)      Debtor's obligations under the Notes and this
                  Security Agreement;

                  (b)      the repayment of (i) any amounts that a Secured Party
                  may advance or spend for the maintenance or preservation of
                  the Collateral, and (ii) any other expenditures that a Secured
                  Party may make under the provisions of this Security Agreement
                  or for the benefit of Debtor;

                  (c)      all amounts owed under any modifications, renewals or
                  extensions of any of the foregoing obligations; and

                  (d)      any of the foregoing that arises after the filing of
                  a petition by or against Debtor under the Bankruptcy Code,
                  even if the obligations do not accrue because of the automatic
                  stay under Bankruptcy Code Section 362 or otherwise.

         1.7      "Permitted Liens" means:

                  (a)      liens on Accounts (as defined in the UCC) securing
                  obligations of Debtor to Banks;

                  (b)      liens existing on the date hereof and listed on
                  Schedule 1.5;

                  (c)      liens for taxes, assessments or charges imposed on
                  Debtor or any of its property by any governmental authority
                  not yet due or which are being contested in good faith and by
                  appropriate proceedings if adequate reserves with respect
                  thereto are maintained on the books of Debtor, in accordance
                  with GAAP or liens for such taxes, assessments or charges
                  which are otherwise permitted under this paragraph;

                  (d)      statutory liens of carriers, warehousemen, mechanics,
                  materialmen, repairmen, or other like liens arising in the
                  ordinary course of business, which are

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                  not overdue for a period of more than 30 days or which are
                  being contested in good faith and by appropriate proceedings;

                  (e)      pledges or deposits required in connection with
                  workers' compensation, unemployment insurance and other social
                  security legislation;

                  (f)      liens incurred on deposits to secure the performance
                  of tenders, bids, trade contracts, leases, statutory
                  obligations, surety and appeal bonds, performance bonds and
                  return-of-money bonds and other obligations of a like nature
                  incurred in the ordinary course of business;

                  (g)      liens in favor of customs and revenue authorities
                  arising as a matter of law and to secure payment of customs
                  duties in connection with the importation of goods

                  (h)      liens securing obligations of Debtor (i) in respect
                  of goods purchased for resale in the ordinary course of
                  business as long as no UCC financing statements are filed
                  concerning such goods or (ii) under true consignment
                  arrangements in which Debtor is the consignee, pursuant to
                  which UCC financing statements may be filed;

                  (i)      liens of landlords or mortgagees of landlords on
                  fixtures and movable property located on premises leased in
                  the ordinary course of business, provided that the rental
                  payments secured thereby are not yet due; and

                  (j)      purchase money liens for Equipment and Inventory in
                  an amount not to exceed $100,000 in the aggregate at any one
                  time.

         1.8      "UCC" Any term used in the Uniform Commercial Code as enacted
         in the State of Ohio or the State where the Collateral is located and
         not defined in this Security Agreement has the meaning (as amended from
         time to time) given to the term in the UCC.

SECTION 2.        GRANT OF SECURITY INTEREST.

         2.1      Security Interest. Debtor grants a security interest in the
                  Collateral to each Secured Party, to secure the payment or
                  performance of the Obligations.

         2.2      Debtor Remains Liable. Anything herein to the contrary
                  notwithstanding, (a) Debtor shall remain liable under any
                  contracts, agreements and other documents included in the
                  Collateral, to the extent set forth therein, to perform all of
                  its duties and obligations thereunder to the same extent as if
                  this Security Agreement had not been executed, (b) the
                  exercise by a Secured Party of any of the rights hereunder
                  shall not release Debtor from any of its duties or obligations
                  under such contracts, agreements and other documents included
                  in the Collateral, and (c) a Secured Party shall not have any
                  obligation or liability under any contracts,

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                  agreements and other documents included in the Collateral by
                  reason of this Security Agreement, nor shall the Secured Party
                  be obligated to perform any of the obligations or duties of
                  Debtor thereunder or to take any action to collect or enforce
                  any such contract, agreement or other document included in the
                  Collateral hereunder.

SECTION 3.        PERFECTION OF SECURITY INTEREST.

         3.1      Filing of Financing Statement.

                  (a)      Debtor shall execute and deliver to the Secured Party
                  concurrently with the execution of this Security Agreement,
                  and Debtor hereby authorizes the Secured Party to file (with
                  or without Debtor's signature) at any time and from time to
                  time thereafter, all financing statements, continuation
                  financing statements, termination statements, security
                  agreements, assignments, warehouse receipts, documents of
                  title, affidavits, reports, notices, schedules of account,
                  letters of authority and all other documents and instruments,
                  in form satisfactory to the Secured Party (the "FINANCING
                  STATEMENTS"), and take all other action, as each Secured Party
                  may request, to perfect and continue perfected, maintain the
                  priority of or provide notice of each Secured Party's security
                  interest in the Collateral and to accomplish the purposes of
                  this Security Agreement.

                  (b)      Each Secured Party's security interest in the
                  Collateral is prior to all other security interests, excepting
                  only the Permitted Liens.

         3.2      Possession.

                  (a)      Debtor shall have possession of the Collateral,
                  except where expressly otherwise provided in this Security
                  Agreement.

                  (b)      Where Collateral is in the possession of a third
                  party, Debtor will join with each Secured Party in notifying
                  the third party of each Secured Party's security interest and
                  obtaining an acknowledgment from the third party that it is
                  holding the Collateral for the benefit of each Secured Party.

SECTION 4.        POST-CLOSING COVENANTS AND RIGHTS CONCERNING THE COLLATERAL.

         4.1      Inspection. A Secured Party may inspect any Collateral, at any
                  time upon reasonable notice.

         4.2      Personal Property. The Collateral shall remain personal
                  property at all times. Debtor shall not affix any of the
                  Collateral to any real property in any manner which would
                  change its nature from that of personal property to real
                  property or to a fixture.

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         4.3      Secured Party's Collection Rights. After the occurrence of,
                  and during the continuance of, an Event of Default, a Secured
                  Party shall have the right at any time to enforce Debtor's
                  rights against Debtor's account debtors and obligors to the
                  extent that such is included in the definition of Collateral.

         4.4      Limitations on Obligations Concerning Maintenance of
                  Collateral.

                  (a)      Debtor has the risk of loss of the Collateral.

                  (b)      A Secured Party shall have no duty to collect any
                  income accruing on the Collateral or to preserve any rights
                  relating to the Collateral.

         4.5      No Disposition of Collateral. Each Secured Party does not
                  authorize, and Debtor agrees not to:

                  (a)      make any sales or leases of any of the Collateral
                  other than the sale of Inventory or other Collateral in the
                  normal course of Debtor's business;

                  (b)      license any of the Collateral, except that Debtor may
                  grant licenses in its Intellectual Property in the ordinary
                  course of its business; or

                  (c)      grant any other security interest in any of the
                  Collateral, except for Permitted Liens.

SECTION 5.        DEBTOR'S REPRESENTATIONS AND WARRANTIES.

         Debtor warrants and represents that:

         5.1      Title to and Transfer of Collateral. Debtor has rights in or
                  power to transfer the Collateral and Debtor is, and will
                  continue to be, the sole and complete owner of the Collateral
                  (or, in the case of after-acquired Collateral, at the time
                  Debtor acquires rights in such Collateral, will be the sole
                  and complete owner thereof), free from any lien except for
                  Permitted Liens, or as created by this Security Agreement.

         5.2      Location, State of Incorporation, and Name of Debtor.

                  (a)      Debtor's chief executive office is located at 425
                  Metro Place North, Suite 300, Dublin, Ohio 43017 in the State
                  of Ohio, county of Franklin, and all Collateral is located at
                  such address or at the addresses set forth on Schedule 5.2 ;

                  (b)      Debtor's state of incorporation is the State of
                  Delaware; and

                  (c)      Debtor's exact legal name is as set forth in the
                  first paragraph of this Security Agreement.

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                  (d)      Debtor has not, at any time in the past two years:
                  (i) been known as or used any other corporate, trade or
                  fictitious name; (ii) changed its name; (iii) been the
                  surviving or resulting corporation in a merger or
                  consolidation; or (iv) acquired through asset purchase or
                  otherwise any business of any person with a purchase price in
                  excess of $1 million, except for the acquisition of Biosonix
                  Ltd.

         5.3      Enforceability of Security Interest.

                  (a)      This Security Agreement creates a security interest
                  which is enforceable against the Collateral in which Debtor
                  now has rights and will create a security interest which is
                  enforceable against the Collateral in which Debtor hereafter
                  acquires rights at the time Debtor acquires any such rights;
                  and

                  (b)      Upon the filing of Financing Statements in the
                  appropriate filing offices in each jurisdiction identified in
                  Schedule 5.2 where Collateral is located and except for
                  Permitted Liens, each Secured Party has a perfected and first
                  priority security interest in the Collateral in which Debtor
                  now has rights, and will have a perfected and first priority
                  security interest in the Collateral in which Debtor hereafter
                  acquires rights at the time Debtor acquires any such rights,
                  in each case securing the payment and performance of the
                  Obligations and in each case in which a security interest can
                  be filed by the filing of a Financing Statement.

         5.4      Other Financing Statements. Other than (a) Financing
                  Statements disclosed to each Secured Party prior to the date
                  hereof and (b) Financing Statements in favor of each Secured
                  Party on behalf of itself, no effective Financing Statement
                  naming Debtor as debtor, assignor, grantor, mortgagor, pledgor
                  or the like and covering all or any part of the Collateral is
                  on file in any filing or recording office in any jurisdiction.

SECTION 6.        DEBTOR'S COVENANTS.

         Until the Obligations are paid in full, Debtor agrees that it will
         preserve its corporate existence, and without the prior written consent
         of each Secured Party (which shall not be unreasonably withheld):

         6.1      Change State of Incorporation. Will not change the state of
                  its incorporation;

         6.2      Change Corporate Name. Will not change its corporate name; and

         6.3      Change Chief Executive Office. Will not change the location of
                  its chief executive office or the place where any material
                  portion of the Collateral is located.

         6.4      Defense of Collateral. Will appear in and defend any action,
                  suit or proceeding which may affect to a material extent its
                  title to, or right or interest in, or the

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                  Secured Party's right or interest in, the Collateral
                  consistent with customary and prudent business practices.

         6.5      Preservation of Collateral. Will do and perform all reasonable
                  acts that may be necessary and appropriate to maintain,
                  preserve and protect the value of the Collateral.

         6.6      Compliance with Laws, Etc. Will comply with all laws,
                  regulations and ordinances, and all policies of insurance,
                  relating in a material way to the possession, operation,
                  maintenance and control of the Collateral if the noncompliance
                  therewith could reasonably result in a material adverse effect
                  on Debtor.

         6.7      Maintenance of Records. Will keep separate, accurate and
                  complete books with respect to the Collateral.

         6.8      Disposition of Collateral. Will not surrender or lose
                  possession of (other than to the Secured Party), sell, lease,
                  rent, or otherwise dispose of or transfer any of the
                  Collateral or any right or interest therein, except in the
                  ordinary course of business.

         6.9      Liens. Will keep the Collateral free of all liens except
                  Permitted Liens and liens created pursuant to this Security
                  Agreement.

         6.10     Expenses. Will pay all validly assessed or incurred expenses
                  of protecting, storing, warehousing, insuring, handling and
                  shipping the Collateral.

         6.11     Inventory. Following the occurrence and during the continuance
                  of any Event of Default, will: (a) if requested by a Secured
                  Party, prepare and deliver to each Secured Party a report of
                  all Inventory, in form and substance satisfactory to each
                  Secured Party; (b) (i) other than with respect to any
                  Inventory in the possession of a subcontractor of Debtor, not
                  store any material portion of Inventory with a bailee,
                  warehouseman or similar person or on premises leased to Debtor
                  without prior notice to each Secured Party and (ii), except
                  with respect to demonstration models, Inventory transferred as
                  upgrades to existing customers and Inventory shipped to
                  customers awaiting customer acceptance, in each instance in
                  the ordinary course of Debtor's business, not dispose of any
                  material portion of Inventory on a bill-and-hold, guaranteed
                  sale, sale and return, sale on approval, consignment or
                  similar basis, nor acquire any material portion of Inventory
                  from any person on any such basis without in each case giving
                  the Secured Party prior written notice thereof.

         6.12     Notices, Reports and Information. Following the occurrence and
                  during the continuance of any Event of Default, will (a)
                  notify each Secured Party of any

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                  material claim made or asserted against the Collateral by any
                  person and of any change in the basic nature of the Collateral
                  or other event which could materially adversely affect the
                  value of the Collateral or a Secured Party's lien thereon
                  (other than commodity fluctuations affecting Debtor's industry
                  generally); (b) furnish to each Secured Party such statements
                  and schedules further identifying and describing the
                  Collateral and such other reports and other information in
                  connection with the Collateral as a Secured Party may
                  reasonably request, all in reasonable detail; and (c) upon
                  request of a Secured Party make such demands and requests for
                  information and reports as Debtor is entitled to make in
                  respect of the Collateral.

         6.13     Insurance.

                  (a)      Shall carry and maintain in full force and effect, at
                  the expense of Debtor and with financially sound and reputable
                  insurance companies, insurance with respect to the Inventory
                  in such amounts, with such deductibles and covering such risks
                  as is customarily carried by persons engaged in the same or
                  similar business. Following the occurrence and during the
                  continuance of any Event of Default, and upon the request of a
                  Secured Party, Debtor shall furnish each Secured Party with
                  full information as to such insurance carried by it and, if so
                  requested, copies of all such insurance policies.

                  (b)      Following the occurrence and during the continuance
                  of any Event of Default, if any material amount of Inventory
                  shall be materially damaged or destroyed, in whole or in part,
                  by fire or other casualty, Debtor shall give prompt notice
                  thereof to each Secured Party. No settlement on account of any
                  loss on any such Inventory covered by insurance shall be made
                  for less than net book value without the consent of each
                  Secured Party, which shall not be unreasonably withheld. Any
                  payment exceeding $25,000 at any time made to Debtor by any
                  insurer with respect to a casualty relating to all or any part
                  of the Collateral shall be, at the Debtor's option, (i) paid
                  equally to the Secured Parties for application to the
                  Obligations, or (ii) reinvested in the production of Inventory
                  constituting Collateral hereunder, in each case, within 90
                  days of Debtor's receipt of such insurance payment (it being
                  understood that Debtor may elect to make payment to each
                  Secured Party under the preceding clause (i), reinvest the
                  applicable insurance proceeds under the preceding clause (ii),
                  or a combination of both).

SECTION 7.        COSTS AND EXPENSES. Debtor agrees to pay or reimburse on
                  demand:

         7.1      Out of Pocket Expenses. Following the occurrence and during
                  the continuance of any Event of Default, the reasonable
                  out-of-pocket costs and expenses of each Secured Party
                  (including reasonable attorney fees and expenses and search,
                  recording and filing fees and expenses, provided, that the
                  Secured Party shall deliver reasonably detailed statements for
                  such fees and expenses); and in addition, Debtor will pay any
                  such costs and expenses incurred by each Secured

                                        9



                  Party in connection with any amendments, modifications or
                  waivers of the terms of this Security Agreement requested by
                  Debtor;

         7.2      Title Appraisal, etc. Following the occurrence and during the
                  continuance of any Event of Default, all title, appraisal
                  (including the allocated costs of internal appraisal services,
                  provided, that the Secured Party requesting same shall deliver
                  reasonably detailed statements for such fees and expenses),
                  survey, audit, consulting and similar fees, costs and expenses
                  incurred or sustained by a Secured Party in connection with
                  this Security Agreement or the Collateral; and

         7.3      Search Fees, etc. Following the occurrence and during the
                  continuance of any Event of Default, all costs and expenses of
                  each Secured Party, (including reasonable attorney fees and
                  expenses and search, recording and filing fees and expenses,
                  provided, that the Secured Party shall deliver reasonably
                  detailed statements for such fees and expenses), in connection
                  with the enforcement or attempted enforcement of, and
                  preservation of any rights or interests under, this Security
                  Agreement, any out-of-court workout or other refinancing or
                  restructuring or in any bankruptcy case, and the protection,
                  sale or collection of, or other realization upon, any of the
                  Collateral, including all expenses of taking, collecting,
                  holding, sorting, handling, preparing for sale, selling, or
                  the like, and other such expenses of sales and collections of
                  Collateral, and any and all losses, costs and expenses
                  sustained by a Secured Party as a result of any failure by
                  Debtor to perform or observe its obligations contained herein.

SECTION 8.        INTERCREDITOR AGREEMENT. Irrespective of any statement
                  contained in the Note or the Purchase Agreement to the
                  contrary and irrespective of the time, order or method of
                  attachment or perfection of any liens granted thereby or the
                  time or order of filing or recording of financing statements
                  or any other lien, and irrespective of anything contained in
                  any filing or agreement to which any of the Secured Parties
                  may now or hereafter be a party, the Secured Parties hereby
                  agree among themselves that the priorities to be accorded to
                  their respective liens in the Collateral shall be equal. So
                  long as any of the Obligations are outstanding, the Secured
                  Parties shall act jointly in regard to making all
                  determinations, taking all actions and otherwise carrying out
                  any provision of this Agreement. For so long as any of the
                  Obligations now or hereafter owed to the Secured Parties
                  remain outstanding, neither Secured Party shall have the right
                  or the option, without providing notice to and receiving the
                  consent of the other Secured Party, to amend, waive or modify
                  any of the terms or provisions of the Note or Purchase
                  Agreement including without limitation (a) any term or
                  provision regarding the time or method of repayment, (b) the
                  terms upon which such repayment may occur, (c) the amount of
                  periodic payments or (d) the allocation of principal and
                  interest among such payments. Each Secured Party hereby agrees
                  to indemnify the other Secured Party, its successors and
                  assigns harmless from and against any and all claims,
                  liabilities, damages, losses, costs and expenses, including
                  without limitation, reasonable counsel fees, resulting from
                  one Secured Party's exercise of any rights or privileges as a
                  secured party with respect to any of the Collateral or

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                  any proceeds thereof provided that such Secured Party acted
                  with the approval of the other Secured Party and did not act
                  or omit to act in a grossly negligent or reckless manner, or
                  with an intent to cause damage.

SECTION 9.        REMEDIES UPON DEFAULT.

         9.1      General. Upon any Event of Default, the Secured Parties may
                  jointly pursue any remedy available at law (including those
                  available under the provisions of the UCC), or in equity to
                  collect, enforce or satisfy any Obligations then owing,
                  whether by acceleration or otherwise.

         9.2      Specific Remedies. Following the occurrence and during the
                  continuance of any Event of Default, the Secured Parties shall
                  have, in addition to all other rights and remedies granted to
                  it in this Security Agreement, all rights and remedies of a
                  secured party under the UCC and other applicable laws. Without
                  limiting the generality of the foregoing, Debtor agrees that a
                  Secured Party may: (a) peaceably and without notice enter any
                  premises of Debtor, take possession of any Collateral, remove
                  or dispose of all or part of the Collateral on any premises of
                  Debtor or elsewhere, and otherwise collect, receive,
                  appropriate and realize upon all or any part of the
                  Collateral, and demand, give receipt for, settle, renew,
                  extend, exchange, compromise, adjust, or sue for all or any
                  part of the Collateral, as such Secured Party may determine;
                  (b) require Debtor to assemble all or any part of the
                  Collateral and make it available to such Secured Party, at any
                  place and time designated by such Secured Party; (c) secure
                  the appointment of a receiver of the Collateral or any part
                  thereof (to the extent and in the manner provided by
                  applicable law); (d) sell, resell, lease, use, assign,
                  transfer or otherwise dispose of any or all of the Collateral
                  in its then condition or following any commercially reasonable
                  preparation or processing (utilizing in connection therewith
                  any of Debtor's assets, without charge or liability to such
                  Secured Party therefor) at public or private sale, by one or
                  more contracts, in one or more parcels, at the same or
                  different times, for cash or credit or for future delivery
                  without assumption of any credit risk, all as such Secured
                  Party deems advisable; provided, however, that Debtor shall be
                  credited with the net proceeds of sale after application of
                  Section 9.5 only when such proceeds are finally collected by
                  the Secured Party. A Secured Party shall have the right upon
                  any such public sale, and, to the extent permitted by law,
                  upon any such private sale, to purchase the whole or any part
                  of the Collateral so sold, free of any right or equity of
                  redemption, which right or equity of redemption Debtor hereby
                  releases, to the extent permitted by law. Debtor hereby agrees
                  that the sending of notice by ordinary mail, postage prepaid,
                  to the address of Debtor set forth in Section 10.3 of the
                  place and time of any public sale or of the time after which
                  any private sale or other intended disposition is to be made,
                  shall be deemed reasonable notice thereof if such notice is
                  sent 10 days prior to the date of such sale or other
                  disposition or the date on or after which such sale or other
                  disposition may occur, provided that the Secured Party may
                  provide Debtor shorter notice or no notice, to

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                  the extent permitted by the UCC or other applicable law. A
                  Secured Party shall have no obligation to clean up or
                  otherwise prepare the Collateral for sale. A Secured Party has
                  no obligation to attempt to satisfy these Obligations by
                  collecting them from any other person liable for them and a
                  Secured Party may release, modify or waive any Collateral
                  provided by any other person to secure any of the Obligations,
                  all without affecting such Secured Party's right against
                  Debtor. Debtor waives any right it may have to require a
                  Secured Party to pursue any third person or any of the
                  Obligations. A Secured Party may comply with any applicable
                  state or federal law requirements in connection with a
                  disposition of the Collateral and compliance will not be
                  considered adversely to affect the commercial reasonableness
                  of any sale of the Collateral. A Secured Party may sell the
                  Collateral without giving any warranty as to the Collateral. A
                  Secured Party may specifically disclaim any warranties of
                  title or the like. This procedure will not be considered
                  adversely to affect the commercial reasonableness of any sale
                  of the Collateral. If a Secured Party sells any of the
                  Collateral upon credit, Debtor will be credited only with
                  payments actually made by the purchaser, received by such
                  Secured Party, and applied to the indebtedness of the
                  purchaser. In the event the purchaser fails to pay for the
                  Collateral, such Secured Party may resell the Collateral and
                  Debtor shall be credited with the net proceeds of the sales
                  after application of Section 9.5.

         9.3      License Upon Default. For the purpose of enabling a Secured
                  Party to exercise its rights and remedies under this Section
                  9, Debtor grants to each Secured Party, following the
                  occurrence and during the continuance of any Event of Default,
                  an irrevocable, non-exclusive and assignable license
                  (exercisable without payment or royalty or other compensation
                  to Debtor) to use, license or sublicense any Intellectual
                  Property, to enable each Secured Party (among other things) to
                  transfer any of the Intellectual Property or tangible property
                  of Debtor that are included in the Collateral.

         9.4      Proceeds Account. To the extent that any of the Obligations
                  may be contingent, unmatured or unliquidated (including with
                  respect to undrawn amounts under any letters of credit
                  outstanding) at such time as there may exist an Event of
                  Default, a Secured Party may, at his election, (a) retain the
                  proceeds of any sale, collection, disposition or other
                  realization upon the Collateral (or any portion thereof) in a
                  special purpose non-interest-bearing restricted deposit
                  account (the "Proceeds Account") created and maintained by
                  such Secured Party for such purpose (which shall constitute a
                  deposit account included within the Collateral hereunder)
                  until such time as such Secured Party may elect to apply such
                  proceeds to the Obligations, and Debtor agrees that such
                  retention of such proceeds by such Secured Party shall not be
                  deemed strict foreclosure with respect thereto; (b) in any
                  manner elected by a Secured Party, estimate the liquidated
                  amount of any such contingent, unmatured or unliquidated
                  claims and apply the proceeds of the Collateral against such
                  amount; or (c) otherwise proceed in any manner permitted by
                  applicable law. Debtor agrees that the Proceeds Account shall
                  be a blocked account and that upon the irrevocable deposit of
                  funds into the Proceeds Account,

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                  Debtor shall not have any right of withdrawal with respect to
                  such funds. Accordingly, Debtor irrevocably waives until the
                  termination of this Security Agreement in accordance with its
                  terms the right to make any withdrawal from the Proceeds
                  Account and the right to instruct a Secured Party to honor
                  drafts against the Proceeds Account.

         9.5      Application of Proceeds. Subject to Section 9.4, cash proceeds
                  actually received from the sale or other disposition or
                  collection of Collateral, and any other amounts received in
                  respect of the Collateral the application of which is not
                  otherwise provided for herein, shall be payable to each
                  Secured Party on a pro-rata basis against all or any part of
                  the Obligations in the following order: (a) first, to any fees
                  due in respect of the Obligations; (b) next, to any interest
                  due in respect of the Obligations; (c) next, to any principal
                  due in respect of the Obligations; and (d) last, to any other
                  Obligations. Any surplus thereof which exists after payment
                  and performance in full of the Obligations shall be promptly
                  paid over to Debtor or otherwise disposed of in accordance
                  with the UCC or other applicable law. Debtor shall remain
                  liable to each Secured Party for any deficiency which exists
                  after any sale or other disposition or collection of
                  Collateral.

         9.6      Certain Waivers. Debtor waives, to the fullest extent
                  permitted by law, (a) any right of redemption with respect to
                  the Collateral, whether before or after sale hereunder, and
                  all rights, if any, of marshalling of the Collateral or other
                  collateral or security for the Obligations; (b) any right to
                  require a Secured Party (i) to proceed against any person,
                  (ii) to exhaust any other collateral or security for any of
                  the Obligations, (iii) to pursue any remedy in a Secured
                  Party's power, or (iv) to make or give any presentments,
                  demands for performance, notices of nonperformance, protests,
                  notices of protests or notices of dishonor in connection with
                  any of the Collateral.

SECTION 10.       MISCELLANEOUS.

         10.1       Assignment.

                  (a)      This Security Agreement shall bind and shall inure to
                  the benefit of the permitted heirs and assigns of the Secured
                  Party and shall bind all persons who become bound as a debtor
                  to this Security Agreement.

                  (b)      No Secured Party consents to any assignment by Debtor
                  except as expressly provided in this Security Agreement.

                  (c)      Each Secured Party may assign and transfer its rights
                  and interests under this Security Agreement only pursuant to a
                  permitted assignment or transfer of the Note secured hereby.
                  If an assignment is made, Debtor shall render performance
                  under this Security Agreement to the assignee.

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         10.2     Severability. Should any provision of this Security Agreement
                  be found to be void, invalid or unenforceable by a court or
                  panel of arbitrators of competent jurisdiction, that finding
                  shall only affect the provisions found to be void, invalid or
                  unenforceable and shall not affect the remaining provisions of
                  this Security Agreement.

         10.3     Notices. Any notice or other communication required or
                  permitted to be given or made under this Security Agreement
                  (a) shall be in writing, and (b) may be delivered by hand
                  delivery, First Class U.S. Mail (regular, certified,
                  registered or expedited delivery), FedEx, UPS Overnight,
                  Airborne or other nationally recognized delivery service, or
                  fax. The addresses for notice for each party and their counsel
                  are set forth in the Purchase Agreement. All notices shall be
                  served upon the parties at said addresses or such other
                  addresses as they may hereafter direct in writing.

         10.4     Headings. Section headings used in this Security Agreement are
                  for convenience only. They are not a part of this Security
                  Agreement and shall not be used in construing it.

         10.5     Governing Law; Jurisdiction. This Security Agreement is being
                  executed and delivered and is intended to be performed in the
                  State of Ohio and shall be construed and enforced in
                  accordance with the laws of the State of Ohio, without giving
                  effect to any choice of law or conflict of law provision or
                  rule (whether of the State of Ohio or any other jurisdictions)
                  that would cause the application of the laws of any
                  jurisdiction other than the State of Ohio, except to the
                  extent that the UCC provides for the application of the law of
                  Delaware. Each party hereby irrevocably waives personal
                  service of process and consents to process being served in any
                  such suit, action or proceeding by mailing a copy thereof to
                  such party at the address for such notices to it under the
                  Purchase Agreement and agrees that such service shall
                  constitute good and sufficient service of process and notice
                  thereof. Nothing contained herein shall be deemed to limit in
                  any way any right to serve process in any manner permitted by
                  law.

         10.6     Disputes. Any controversy, claim or dispute arising out of or
                  relating to this Security Agreement or the breach,
                  termination, enforceability or validity of this Security
                  Agreement, including the determination of the scope or
                  applicability of the agreement to arbitrate set forth in this
                  Section 10.6 shall be determined exclusively by binding
                  arbitration in the City of Columbus, Ohio. The arbitration
                  shall be governed by the rules and procedures of the American
                  Arbitration Association (the "AAA") under its Commercial
                  Arbitration Rules and its Supplementary Procedures for Large,
                  Complex Disputes; provided that persons eligible to be
                  selected as arbitrators shall be limited to attorneys-at-law
                  each of whom (a) is on the AAA's Large, Complex Case Panel or
                  a Center for Public Resources ("CPR") Panel of Distinguished
                  Neutrals, or has professional credentials comparable to those
                  of the attorneys listed on such AAA and CPR

                                       14



                  Panels, and (b) has actively practiced law (in private or
                  corporate practice or as a member of the judiciary) for at
                  least 15 years in the State of Ohio concentrating in either
                  general commercial litigation or general corporate and
                  commercial matters. Any arbitration proceeding shall be before
                  one arbitrator mutually agreed to by the parties to such
                  proceeding (who shall have the credentials set forth above)
                  or, if the parties are unable to agree to the arbitrator
                  within 15 business days of the initiation of the arbitration
                  proceedings, then by the AAA. No provision of, nor the
                  exercise of any rights under, this Section 10.6 shall limit
                  the right of any party to request and obtain from a court of
                  competent jurisdiction in the State of Ohio, County of
                  Franklin (which shall have exclusive jurisdiction for purposes
                  of this Section 10.6) before, during or after the pendency of
                  any arbitration, provisional or ancillary remedies and relief
                  including injunctive or mandatory relief or the appointment of
                  a receiver. The institution and maintenance of an action or
                  judicial proceeding for, or pursuit of, provisional or
                  ancillary remedies shall not constitute a waiver of the right
                  of any party, even if it is the plaintiff, to submit the
                  dispute to arbitration if such party would otherwise have such
                  right. Each of the parties hereby submits unconditionally to
                  the exclusive jurisdiction of the state and federal courts
                  located in the County of Franklin, State of Ohio for purposes
                  of this provision, waives objection to the venue of any
                  proceeding in any such court or that any such court provides
                  an inconvenient forum and consents to the service of process
                  upon it in connection with any proceeding instituted under
                  this Section 9.6 in the same manner as provided for the giving
                  of notice under this Security Agreement. Judgment upon the
                  award rendered may be entered in any court having
                  jurisdiction. The parties hereby expressly consent to the
                  nonexclusive jurisdiction of the state and federal courts
                  situated in the County of Franklin, State of Ohio for this
                  purpose and waive objection to the venue of any proceeding in
                  such court or that such court provides an inconvenient forum.
                  The arbitrator shall have the power to award recovery of all
                  costs (including attorneys' fees, administrative fees,
                  arbitrators' fees and court costs) to the prevailing party.
                  The arbitrator shall not have power, by award or otherwise, to
                  vary any of the provisions of this Security Agreement.

         10.7     Rules of Construction.

                  (a)      No reference to "proceeds" in this Security Agreement
                  authorizes any sale, transfer, or other disposition of the
                  Collateral by Debtor.

                  (b)      "Includes" and "including" are not limiting.

                  (c)      "Or" is not exclusive.

                  (d)      "All" includes "any" and "any" includes "all."

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         10.8     Integration and Modifications.

                  (a)      This Security Agreement, together with each Note and
                  each Purchase Agreement, constitute the entire agreement of
                  Debtor and each Secured Party concerning the subject matter
                  hereof.

                  (b)      Any modifications to this Security Agreement must be
                  made in writing and signed by the party adversely affected.
                  10.9 Waiver. Any party to this Security Agreement may waive
                  the enforcement of any provision to the extent the provision
                  is for its benefit.

         10.10    Further Assurances. Debtor agrees to execute any further
                  documents, and to take any further actions, reasonably
                  requested by a Secured Party to evidence or perfect the
                  security interest granted herein, to maintain the first
                  priority of the security interest or to effectuate the rights
                  granted to a Secured Party herein.

         The parties have signed this Security Agreement as of the day and year
first above written at Franklin County, Ohio.

                                             "DEBTOR"

                                             NEOPROBE CORPORATION

                                             By: Brent L. Larson
                                                ----------------------------
                                             Name: Brent L. Larson
                                             Its:  Vice President-Finance

                                             "SECURED PARTIES"

                                                 /s/ David C. Bupp
                                             -------------------------------
                                                     David C. Bupp

                                                 /s/ Donald E. Garlikov
                                             -------------------------------
                                                     Donald E. Garlikov

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