EXHIBIT 10.01

[***] indicates the omission of confidential portions for which confidential
treatment has been requested. Such confidential information has been filed
separately with the Commission.
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                             CARDINAL DISTRIBUTION*

                                       AND

                              EXPRESS SCRIPTS, INC.

                             PRIME VENDOR AGREEMENT









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                             PRIME VENDOR AGREEMENT

         THIS PRIME VENDOR AGREEMENT (THE "AGREEMENT") IS MADE JULY 1, 2001,
BETWEEN EXPRESS SCRIPTS, INC., ON BEHALF OF ITSELF AND ITS SUBSIDIARIES
(COLLECTIVELY, "BUYER") AND CARDINAL DISTRIBUTION* ("CARDINAL"), WHO HEREBY
AGREE AS FOLLOWS:


1.       DESIGNATION AS PRIMARY WHOLESALER

                  During the term of this Agreement, Buyer will designate
         Cardinal as the primary wholesale pharmaceutical supplier to all
         pharmacies whether now or hereafter owned, managed or operated by Buyer
         in the United States (collectively, the "PHARMACIES" and individually,
         a "PHARMACY"). A current list of the Pharmacies is attached hereto as
         EXHIBIT A. Additional pharmacies may be added to Exhibit A from time to
         time subject to the prior approval of Buyer and Cardinal.

2.       SALE OF MERCHANDISE

                  Buyer will purchase from Cardinal during the term of this
         Agreement its Primary Wholesale Requirements of pharmaceuticals for the
         Pharmacies ("RX PRODUCTS") and, may, at its option, purchase certain
         other inventory carried by Cardinal ("NON-RX PRODUCTS" and, together
         with Rx Products, collectively the "MERCHANDISE") for delivery directly
         to the Pharmacies ("DIRECT STORE DELIVERY Purchases"). The term
         "PRIMARY WHOLESALE REQUIREMENTS" means that Buyer will purchase for
         each Pharmacy all of its requirements of Rx Products purchased from
         wholesalers from Cardinal. With the exception of Merchandise that is
         only available from the manufacturer with less than six (6) months'
         dating, Cardinal removes Merchandise from its inventory that has an
         expiration date of six (6) months, not including the current month, so
         that such Merchandise shipped to Buyer has a minimum of six (6) months'
         dating. Cardinal reserves the right at all times to determine what
         Merchandise it will carry based upon product quality, manufacturer
         indemnity, insurance, and other policies, and other standards
         determined by it, and may delete from its available inventory items of
         Merchandise with limited or no movement activity.

                  Cardinal acknowledges that Buyer, from time to time, [***],
         including [***]

3.       PURCHASE PRICE

                  Buyer will pay a purchase price for all Merchandise purchased
         under this Agreement in an amount equal to Cardinal's Cost plus the
         percentage specified in the pricing matrix attached hereto as EXHIBIT B
         (the "PRICING MATRIX"). For purposes of this Agreement: (a) the term
         "CARDINAL'S COST" will mean the manufacturer's published wholesale
         acquisition cost for Merchandise at the date of Cardinal's invoice to
         the Pharmacy, including all discounts, price reductions and promotions
         offered off-invoice by the manufacturer for the duration of the
         manufacturer's offer period, but without reduction for customary cash
         discounts; and (b) the term "QUALIFIED PURCHASES" will

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         mean all purchases made and paid for by Buyer and/or the Pharmacies
         under the terms of this Agreement, net of all returns, credits,
         rebates, late charges, or other similar items, on an annual, quarterly,
         or monthly basis, as applicable. Notwithstanding anything herein to the
         contrary, the purchase price of Merchandise which is subject to a
         Manufacturer Contract (as hereinafter defined) will be Buyer's contract
         price for the Pharmacies. Cardinal reserves the right to adjust the
         purchase price of any item of Merchandise in the event that the
         manufacturer of such item implements a change in policy which
         eliminates or decreases the customary cash discount terms effective on
         the Commencement Date with respect to such item.

                  The purchase price for selected Merchandise, including but not
         limited to [***] described above [***] in accordance with [***].
         Merchandise described in this paragraph is sometimes referred to as
         [***]

                  The pricing specified in the Pricing Matrix does not reflect
         administrative fees for membership in any group purchasing organization
         (a "GPO"). If any Pharmacy affiliates with a GPO, the appropriate
         administrative fee will be added to the percentages specified in the
         Pricing Matrix.

                  [***] CardinalCHOICE(R) pharmacy system [***] for the pricing
         specified in the Pricing Matrix.

4.       [***] AND SAVINGS

                  During the initial term of this Agreement, [***] with related
         savings as more fully described on EXHIBIT C.

5.       PAYMENT TERMS

                  (a) Initial Payment Terms. The payment terms initially
         applicable to Buyer will be as follows:

                           (i) For DIRECT STORE DELIVERY PURCHASES, Buyer shall
                  cause Cardinal to receive payment in full by not later than
                  [***] of each calendar month of the amount due for all
                  Merchandise delivered and services provided during the first
                  (1st) [***] of such calendar month, and by not later than the
                  [***] of each calendar month, of the amount due for all
                  Merchandise delivered and services provided during the period
                  beginning on the [***] of the preceding calendar month and
                  ending on the last day of such preceding calendar month [***].

                           (ii) For [***] (I.E., [***]

                           (iii) For [***] in accordance with the terms set
                  forth in Exhibit C [***]

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                  If any payments are due on Saturday, Buyer will cause Cardinal
         to receive payment in full on the immediately preceding Friday, and if
         payment is due on Sunday, Buyer will cause Cardinal to receive payment
         in full on the immediately following Monday.

                  Buyer will deliver to Cardinal any credit information
         reasonably requested by Cardinal not less than thirty (30) days prior
         to its initial purchases of Merchandise under this Agreement. All
         payments for the Merchandise purchased under this Agreement will be due
         in accordance with the terms set forth above unless and until otherwise
         agreed by Buyer and Cardinal. In such event, Buyer acknowledges and
         agrees that Buyer's Cost of Goods may be adjusted by Cardinal to
         reflect Buyer's new payment terms and credit considerations deemed
         relevant to Cardinal.

                  (b) Payment. At the end of each calendar month, Cardinal will
         evaluate Buyer's payment history, adjusted to reflect legitimately
         disputed amounts. The due date of each Cardinal invoice will be
         compared with the date Cardinal received payment to relieve that
         invoice. Buyer and Cardinal acknowledge that Buyer's cost to purchase
         Merchandise from Cardinal is based upon Buyer making payments in
         accordance with Buyer's applicable payment terms as set forth above.

                  For those invoices paid after the applicable due date, Buyer
         will pay to Cardinal an amount equal to [***] times the amount of each
         invoice times the number of days the payment to relieve the invoice was
         late. Cardinal will provide an invoice to Buyer for all amounts due
         hereunder by the 10th of the following month. Such invoice will reflect
         the amount due to Cardinal for those invoices that were paid beyond
         Buyer's applicable payment terms. This invoice will be accompanied by
         an electronic file that will detail the calculation of all amounts due.
         Buyer shall remit payment for such invoice by the 20th of the month in
         which it was billed. Failure or delay by Cardinal to bill Buyer for any
         amounts due hereunder shall not waive Cardinal's right to receive the
         same.

                  All payments for Merchandise delivered and services provided
         by Cardinal will be made to the applicable servicing division specified
         in Cardinal's invoice (or as otherwise specified by Cardinal) by
         electronic funds transfer or other method acceptable to Cardinal so as
         to provide Cardinal with good funds by the due date. In addition to all
         other rights and remedies contained in this Agreement, Cardinal retains
         the right, in its sole discretion, but exercising good faith, to
         immediately, upon written notice to Buyer, change Buyer's payment terms
         or place Buyer on C.O.D. status if Cardinal has not received payment
         when due for Merchandise delivered or services provided to Buyer, or
         based upon credit considerations deemed relevant by Cardinal, as
         determined by Cardinal in good faith. The provisions of Sections 25 and
         26 shall not be applicable to this provision.

                  If Cardinal changes Buyer's payment terms or places Buyer on
         C.O.D. status pursuant to this Section 5(b), and Buyer remains subject
         to such payment terms for at least ninety (90) consecutive days, or on
         C.O.D. for at least sixty consecutive (60) days, Buyer may terminate
         this Agreement upon written notice to Cardinal and payment of all


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         outstanding amounts due from Buyer to Cardinal. No termination notice
         from Buyer to Cardinal shall be effective until all outstanding amounts
         due from Buyer to Cardinal are paid in full. During the applicable time
         period, Cardinal and Buyer shall negotiate in good faith regarding
         restoring Buyer's payment terms to those in effect prior to any action
         taken by Cardinal hereunder.

                  (c) Submission of Financial Statements. Buyer will provide
         Cardinal with a copy of its publicly available financial statements as
         Cardinal may reasonably request from time to time.

                  (d) Guaranty. As an inducement for Cardinal to supply
         Merchandise and provide services to the subsidiaries and affiliates of
         Buyer, whether existing now or in the future (collectively,
         "Borrowers"), Buyer (i) guarantees to Cardinal the punctual and full
         payment (and not merely the ultimate collectability) of all sums now or
         hereafter due from Borrowers to Cardinal and (ii) agrees to pay to
         Cardinal on demand the reasonable cost and expense incurred by Cardinal
         in attempting to enforce any indebtedness, liability, or obligation
         under this Agreement, including, without limitation, reasonable
         attorney's fees.

6.       ORDERING AND DELIVERY

                  Cardinal will deliver the Merchandise F.O.B. destination to
         the applicable Pharmacy and exercise its good faith efforts to provide
         an efficient delivery schedule designed to meet the mutual needs of
         Cardinal and the Pharmacies, in accordance with Cardinal's general
         delivery schedules established from time to time by the applicable
         Cardinal servicing division (exclusive of holidays, etc.). All
         deliveries will be accompanied by an invoice and all delivery costs
         (not including emergency deliveries) absorbed by Cardinal. Pharmacies
         having Qualified Monthly Purchases in excess of $[***] will be eligible
         to receive [***], except Pharmacies located outside of the contiguous
         United States or other Pharmacies mutually agreed upon by the parties
         from time to time; provided, however, Buyer's Pharmacies located in
         Tempe, Arizona, Albuquerque, New Mexico, and St. Louis, Missouri, will
         be eligible to receive [***]. Buyer will incur a separate delivery
         charge, not to exceed Cardinal's actual cost, for additional
         deliveries. Delivery schedules and purchase order deadlines may be
         reviewed and changed from time to time as mutually agreed upon by
         Cardinal and Buyer. Cardinal will make every reasonable effort to
         accommodate individual order entry and delivery requirements.

                  Buyer will submit all orders, except for orders for Schedule
         II drugs, for all Merchandise to Cardinal via electronic order entry
         using equipment supplied by Cardinal to Buyer at no additional charge
         to Buyer or other mutually agreeable electronic means. This equipment
         benefits Buyer and the Pharmacies and relates to the provision of
         products and services by Cardinal hereunder. Buyer and each Pharmacy
         agree not to use such equipment (including hardware and software) for
         any purpose unrelated to this Agreement. Any such equipment supplied by
         Cardinal will be returned to Cardinal by Buyer upon the expiration or
         termination of this Agreement for any reason or prior to termination or
         expiration if Cardinal reasonably believes its proprietary rights are


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         threatened. In the event that electronic order entry is temporarily
         interrupted for reasons beyond the control of Buyer or Cardinal, Buyer
         may place orders manually and both parties will use reasonable efforts
         to rectify the problem.

                  DEA Form 222 may be mailed to the applicable Cardinal
         distribution center or given to the delivery driver. Schedule II orders
         will be delivered within one (1) day of Cardinal's receipt of the
         signed original DEA Form 222. Buyer acknowledges that if Buyer gives
         the DEA Form 222s to the delivery driver, such forms will not be
         received by Cardinal until such time that the delivery driver
         physically delivers the DEA Form 222 to the applicable Cardinal
         distribution center. Notwithstanding the foregoing, no Schedule II
         orders will be delivered other than in compliance with DEA regulations.

7.       OTHER SERVICES

                  Cardinal will provide the services to Buyer and the Pharmacies
         as set forth EXHIBIT D to this Agreement, pursuant to the terms and
         conditions contained therein.

8.       EMERGENCY DELIVERIES

                  Cardinal will provide a twenty-four (24) hour, seven (7) day
         per week emergency delivery service. The courier charge for such orders
         will be prepaid by Cardinal and added to Buyer's invoice. A listing of
         key management personnel and emergency order procedures will be
         supplied to each Pharmacy.

9.       BACKORDER RELAY

                  [***] a "backorder relay" system [***].

10.      MANUFACTURER CONTRACT ADMINISTRATION

                  Cardinal will recognize and administer manufacturer contracts
         between Buyer and any manufacturer (collectively, "MANUFACTURER
         CONTRACTS") subject to such Manufacturer Contracts' continued validity
         in accordance with applicable laws and subject to such credit
         considerations concerning the applicable manufacturers as Cardinal may
         consider appropriate; however, if manufacturers' chargebacks for
         contract items submitted by Cardinal are disallowed, uncollectable, or
         unreconcilable, then the applicable charge will be billed back to
         Buyer. Cardinal reserves the right, at any time, to decline to sell or
         carry any manufacturer's merchandise, based upon credit considerations
         deemed relevant to Cardinal. Buyer will notify Cardinal of all
         Manufacturer Contracts. In addition, Buyer or the Pharmacies will
         provide Cardinal with a copy of all new Manufacturer Contracts entered
         into after the Commencement Date and manufacturer verification of all
         renewals, replacements or terminations of Manufacturer Contracts not
         less than forty-five (45) days prior to the effective date of such new
         Contract, renewal, replacement or termination. Failure to comply with
         these notice requirements will entitle Cardinal to discontinue the
         service level provisions herein until forty-five (45) days after
         delivery of accurate usage data for the new items.

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                  In order to facilitate Cardinal's inventory management
         requirements, Buyer will provide Cardinal, with respect to each
         Pharmacy not currently being serviced by Cardinal, but to be included
         hereunder as a Pharmacy, available six (6) months' usage figures
         (including NDC numbers) on both contract and non-contract items in
         compatible electronic (disk) format thirty (30) days prior to
         participation under this Agreement by that Pharmacy. The service level
         provisions set forth in Section 12 below will be waived by Buyer until
         accurate usage figures are obtained by Cardinal with regard to such
         Pharmacies, or for six (6) months, whichever is less. All purchases
         under this Agreement by Buyer will be for the Pharmacies' "own use" as
         that term is defined in judicial or legislative interpretation, and
         Buyer will comply with applicable manufacturers' pricing criteria and
         policies.

11.      LICENSURE

                  Buyer attests to Cardinal that Buyer's Pharmacies are all
         properly licensed with applicable state licensing agencies to receive,
         dispense, distribute and otherwise legally dispose of Rx Products.
         Buyer understands that by attesting to this, Cardinal is complying with
         the "good faith inquiry" standard to ensure that Rx Products are
         distributed to properly licensed and/or registered pharmacy locations.
         Prior to purchasing Rx Products from Cardinal hereunder, Buyer will
         provide Cardinal with copies of all such licenses and any renewals,
         revocations or other changes to the same.

12.      SERVICE LEVEL

                  For [***] Cardinal will exercise all reasonable efforts to
         provide [***] ([***]%) [***] in accordance with Cardinal's customary
         standards and procedures in effect from time to time. [***] ([***]%)
         [***] ([***]%) [***] ([***]%) [***] For example, [***]
         $[***]%[***]$[***]([***])[***]% -[***]% = [***]% and ([***])[***]% x
         $[***]x[***]% = $[***]([***])[***].

                  Buyer may, [***] ([***]%), [***] (as hereinafter defined) and
         [***]

                  Notwithstanding [***] set forth above, [***] in accordance
         with Cardinal's customary standards and procedures in effect from time
         to time is [***] ([***]%), [***] as set forth above) [***] ([***]%)
         [***].

13.      RETURNED GOODS POLICY

                  Cardinal will accept Merchandise for return from Pharmacies in
         accordance with the Standard Cardinal Returned Goods Policy (the
         "CARDINAL RETURNS POLICY") in effect from time to time. Cardinal will
         not accept for return any Merchandise from Buyer prior to execution of
         an Ongoing Assurances Form in the identical form as attached as an
         exhibit hereto. Cardinal will work with a third party returned goods
         processor in accordance with the Standard Third Party Returned Goods
         Policy (the "THIRD PARTY RETURNS POLICY") in effect from time to time.
         In connection with the Cardinal Returns

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         Policy and applicable law, Buyer will execute a Cardinal Health Return
         Goods Authorization Ongoing Assurance, in the form attached hereto as
         EXHIBIT E.

                  For [***], subject to the following conditions:

                  [***] and must be[***]
                  [***] and[***]
                  [***]
                  [***]
                  [***]percent ([***]%) [***].
                  [***].

14.      TERM

                  The initial term of this Agreement will be for a period of
         three (3) years beginning July 1, 2001 (the "COMMENCEMENT DATE").
         Thereafter, this Agreement shall automatically renew for two (2)
         additional one (1) year renewal terms, unless either party provides
         written notice of non-renewal at least ninety (90) days prior to the
         expiration of the initial term or the then current renewal term. The
         "initial term" and any "renewal terms" shall be referred to
         collectively as the "term."

                  Either party may effect an early termination of this Agreement
         upon the occurrence of a material breach by the other party and such
         party's failure to cure such material breach within ninety (90) days
         after the non-breaching party provides written notice thereof. For
         purposes of this Agreement, a lower-priced offer from a competitor of
         Cardinal to Buyer to provide the Merchandise and perform the services
         as set forth in this Agreement, shall not be deemed to, nor shall it
         constitute, a material breach of this Agreement by Cardinal, thereby
         permitting Buyer to terminate this Agreement pursuant to the provisions
         of this Section 14.

                  Notwithstanding the foregoing, with respect to payment
         defaults by Buyer, Cardinal may terminate this Agreement immediately.
         Buyer's obligation to pay Cardinal any amounts due hereunder shall
         survive termination of this Agreement.

15.      NOTICES

                  Any notice or other communication required or desired to be
         given to either party under this Agreement shall be in writing and
         shall be deemed given when: (a) received by the recipient, after being
         sent via certified mail, return receipt requested, and addressed to
         that party at the address for such party set forth at the end of this
         Agreement; (b) received by the recipient after being sent via Federal
         Express, Airborne, or any other similar overnight delivery service for
         delivery to that party at that address; or (c) received by facsimile
         transmission, as evidenced by electronic confirmation, to that party at
         its facsimile number set forth at the end of this Agreement. Either
         party may change its address or facsimile number for notices under this
         Agreement by giving the other party notice of such change.

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16.      TAXES/COMPLIANCE WITH LAWS

                  Buyer will pay when due any sales, use, excise, gross
         receipts, or other federal, state, or local taxes or other assessments
         (other than any tax based solely on the net income of Cardinal) and
         related interest and penalties in connection with or arising out of the
         transactions contemplated by this Agreement. If Cardinal pays any such
         amounts which Buyer is obligated to pay under this section, then Buyer
         will promptly reimburse Cardinal in an amount equal to the amount so
         paid by Cardinal.

                  If and to the extent any discount, credit, rebate or other
         purchase incentive (as set forth in the Pricing Matrix and this
         Agreement) is paid or applied by Cardinal with respect to the
         Merchandise purchased under this Agreement, such discount, credit,
         rebate or other purchase incentive shall constitute a "discount or
         other reduction in price," as such terms are defined under the
         Medicare/Medicaid Anti-Kickback Statute, on the Merchandise purchased
         by Buyer under the terms of this Agreement. Cardinal and Buyer agree to
         use their best efforts to comply with any and all requirements imposed
         on sellers and buyers, respectively, under 42 U.S.C. ss.
         1320a-7b(b)(3)(A) and the "safe harbor" regulations regarding discounts
         or other reductions in price set forth in 42 C.F.R. ss. 1001.952(h). In
         this regard, Buyer may have an obligation to accurately report, as may
         be required, under any state or federal program which provides cost or
         charge based reimbursement for the products or services covered by this
         Agreement, the net cost actually paid by Buyer.

17.      FORCE MAJEURE

                  Cardinal's obligations under this Agreement will be excused if
         and to the extent that any delay or failure to perform such obligations
         is due to fire or other casualty, product or material shortages,
         strikes or labor disputes, transportation delays, manufacturer
         out-of-stock or delivery disruptions, acts of God, seasonal supply
         disruptions, or other causes beyond the reasonable control of Cardinal.
         During the period of any such delay or failure, Buyer may purchase the
         Primary Wholesale Requirements for the affected Pharmacies from others,
         but will recommence purchasing from Cardinal upon cessation of such
         delay or failure; provided, however, that if such delay or failure
         continues for more than sixty (60) calendar days, Buyer shall have the
         right to immediately terminate this Agreement.

18.      RECORDS AND AUDIT

                  Cardinal will maintain records pertaining to this Agreement
         and the pharmaceutical products purchased by Buyer hereunder as
         required by applicable FDA requirements. Not more than once in any
         twelve (12) month period, and following sixty (60) days' advance
         written notice to Cardinal, Buyer will have the right to appoint one
         (1) or more of its employees to review those relevant records
         applicable to its pharmaceutical purchases for the sole purpose of
         verifying compliance with this Agreement, including but not limited to
         the pricing terms of this Agreement hereof; provided, however, any

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         information proprietary to Cardinal, as solely determined by Cardinal,
         shall be redacted from such records prior to review by Buyer, further
         provided, however, Cardinal shall ensure that Buyer receives the
         information necessary to verify compliance with this Agreement. Any
         such review will be limited to twelve (12) months of historical
         information as of the date such review begins and will be subject to a
         confidentiality agreement prepared by Cardinal and signed by the Buyer
         and its employee(s) who will have access to the information prior to
         beginning the review.

                  Cardinal will have the right to, following sixty (60) days'
         advance written notice to Buyer, appoint an independent auditor to
         review Buyer's purchase records in order to verify the growth rate of
         Buyer's purchase volume for purposes of the savings related to the
         [***].

19.      RETURN OF HARDWARE/SOFTWARE

                  Upon termination of this Agreement for any reason, Buyer's
         rights as a licensee of the CardinalCHOICE(R), CardinalCHOICE(R)-HQ or
         other Cardinal software will automatically expire, and Buyer will
         promptly return such software and any related, Cardinal-provided
         hardware not purchased by Buyer to a return location specified by
         Cardinal.

20.      ENTIRE AGREEMENT; SUCCESSORS

                  This Agreement and its exhibits constitutes the entire
         agreement and understanding of the parties with respect to the subject
         matter hereof, and supersedes all prior and contemporaneous agreements,
         proposals, bids/bid responses, and understandings between the parties
         relative to the subject matter of this Agreement. This Agreement will
         be governed by Ohio law. Neither Cardinal nor Buyer may assign its
         rights under this Agreement without the written consent of the other;
         provided, however, that either party may delegate its rights and
         obligations to any entity that is controlled by or under common control
         with the assigning party; provided that neither Cardinal nor Buyer
         shall be relieved of their respective liabilities and obligations
         hereunder in the event of such an assignment. This Agreement will be
         binding on, inure to the benefit of, and be enforceable by and against
         the respective successors and assigns of each party to this Agreement.

21.      AMENDMENTS

                  No changes to this Agreement will be made or be binding on any
         party unless made in writing and signed by each party to this
         Agreement.

22.      WAIVER

                  The failure of either party to enforce any provision of this
         Agreement will not be considered a waiver of any future right to
         enforce such provision.

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23.      ANNOUNCEMENTS

                  Neither party will issue any press release or other public
         announcement, verbally or in writing, referring to the other party or
         any entity which is controlled by or under common control with such
         other party, without such other party's prior written consent and
         advice of counsel. A written copy of any such press release or other
         public announcement will be provided to the other party no less than
         seventy-two (72) hours prior to the issuing party's intent to issue
         such release or announcement. The issuing party is responsible for
         confirming in writing that the other party has received any such
         proposed press release. Any such press release or other public
         announcement proposed by either party will be subject to the other
         party's revision and final approval. Nothing contained herein will
         limit the right of either party to issue a press release if, in the
         opinion of such party's counsel, a press release is required pursuant
         to state or federal securities laws, rules or regulations.

24.      CHANGE IN LAWS

                  Notwithstanding any other provision of this Agreement, if the
         governmental agencies that administer the Medicare, Medicaid, or other
         federal programs (or their representatives or agents), or any other
         federal, state, or local governmental or non-governmental agency, or
         any court or administrative tribunal passes, issues, or promulgates any
         law, rule, regulation, standard, interpretation, order, decision, or
         judgment, including, but not limited to, those relating to any
         regulation pursuant to state or federal anti-kickback or self-referral
         statutes (collectively or individually, "Change in Laws"), which, in
         the good faith judgment of a party to this Agreement (the "Noticing
         Party"), materially and adversely affects that party's license,
         accreditation, certification, or ability to refer, to accept any
         referral, to bill, to claim, to present a bill or claim, or to receive
         payment or reimbursement from any federal, state, or local governmental
         or non-governmental payor, or which subjects the Noticing Party to a
         risk of prosecution or civil monetary penalty, or which, in the good
         faith judgment of the Noticing Party, indicates a rule or regulation
         with which the Noticing Party desires further compliance and the Change
         in Laws has a material affect on the legality of this Agreement, or if
         Cardinal believes such Change in Laws may adversely affect Cardinal's
         financial position, then the Noticing Party may give the other party
         notice of intent to amend or terminate this Agreement. Such notice
         shall include an opinion of counsel stating: (i) the Change in Laws
         giving rise to the notice; (ii) the consequences of the Change in Laws
         as to the Noticing Party; (iii) the Noticing Party's intention either
         to terminate this Agreement due to an unacceptable risk of prosecution
         or civil monetary penalty or to amend this Agreement, together with a
         statement setting forth the specific purpose of the amendment as it
         relates to the legal compliance issue or risk that the Noticing Party
         seeks to address; (iv) the Noticing Party's proposed amendment(s); and
         (v) the Noticing Party's request for commencement of the Renegotiation
         Period (as hereinafter defined). If the notice provides for an
         amendment of this Agreement, the parties have ten (10) days from the
         giving of the notice ("Renegotiation Period") within which to attempt
         to amend this Agreement in accordance with the Noticing Party's
         proposal (if any) or otherwise as the parties may agree. If this
         Agreement is not amended within the Renegotiation Period,

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                                       11


         this Agreement will automatically terminate as of midnight on the tenth
         (10th) day after notice was given, or as otherwise may be mutually
         agreed upon by the parties. Except as otherwise required by applicable
         law, any amounts then-owing to either party must be paid up to the date
         of termination, and any obligation under this Agreement that is to
         continue beyond expiration or termination must so continue pursuant to
         its terms. All opinions of counsel presented by the Noticing Party, and
         any corresponding opinions given by the other party are Confidential
         Information solely for purposes of renegotiation and settlement of a
         potential dispute, and must not be deemed disclosed so as to waive any
         privileges otherwise applicable to the opinions.

25.      DISPUTE RESOLUTION

                  Any dispute relating to this Agreement which the parties are
         unable to resolve by mutual agreement and meeting of the Executive
         Resolution Committee shall be settled by a sole arbitrator in a
         binding, non-reviewable and non-appealable alternative dispute
         resolution process conducted in accordance with the procedures set
         forth on EXHIBIT F. The existence of the dispute, the dispute
         resolution process, and the arbitrator's award shall be maintained
         confidential, provided that the arbitrator's award may be entered as a
         final judgment in any court having jurisdiction.

26.      EXECUTIVE RESOLUTION COMMITTEE

                  From time to time during the term of this Agreement, upon the
         request of either party, a panel consisting of two (2) executives from
         Buyer and two (2) executives from Cardinal (the "EXECUTIVE RESOLUTION
         COMMITTEE") will meet to review issues pertaining to this Agreement
         raised by either party, resolve disputes relating to this Agreement and
         address other issues as they may determine. Each executive on the
         Executive Resolution Committee shall be of the Senior Vice President
         level, or higher, and the identity of the executives from each party
         shall be determined based upon the issue or dispute presented. Except
         as otherwise set forth herein, the Executive Resolution Committee shall
         meet within forty-five (45) days of the request by either party. With
         respect to disputes, a copy of the terms of this Agreement, agreed upon
         facts and areas of disagreement, and a concise summary of the basis for
         each side's contentions will be provided to the Executive Resolution
         Committee who will review the same, confer, and attempt to reach a
         mutual resolution of the issue. If the Executive Resolution Committee
         is unable to reach a mutual resolution with regard to any dispute
         related to this Agreement, such dispute shall be settled in accordance
         with the dispute resolution process set forth in Section 25 of this
         Agreement.

27.      SEVERABILITY

                  Should, by any reason, any clause or provision of this
         Agreement be held or ruled unenforceable or ineffective under the law,
         such a ruling will in no way affect the validity or the enforceability
         of any other clause or provision contained herein.

28.      CONFIDENTIALITY

- --------------------------------------------------------------------------------
                                       12


                  Each party acknowledges that as a result of this Agreement,
         that party will learn confidential information of the other party. As
         used in this Agreement, the term "Confidential Information" includes
         all such information furnished by Cardinal or Buyer, any Pharmacy, or
         any of their respective representatives, to the other or its
         representatives, whether furnished before, on or after the date hereof
         and regardless of the manner in which it is furnished. Confidential
         Information includes all analyses, compilations, business or technical
         information and other materials prepared by Cardinal or Buyer, any
         Pharmacy, or any of their respective representatives, containing or
         based in whole or in part on any such information furnished by the
         other party or its representatives. Confidential Information also
         includes the existence of this Agreement and the terms and conditions
         hereof. Neither party will disclose any Confidential Information of the
         other party to any third party, or use, or permit any third party to
         use, any of such Confidential Information, excepting only: (a)
         disclosures on a confidential basis to and use by the directors,
         officers, employees, and agents of that party or its affiliates who
         have a reasonable need to know such information in connection with that
         party's performance of this Agreement, (b) disclosures which are
         required by law, as reasonably determined by that party or its legal
         counsel, or are made on a confidential basis to that party's attorneys,
         accountants, and other professional advisors in connection with matters
         relating to this Agreement, and (c) routine disclosures in the normal
         course of business, including to IMS/DDD or similar organizations and
         manufacturers.

                  The obligations of confidentiality hereunder will survive the
         termination of this Agreement for a period of three (3) years, unless
         otherwise mutually agreed upon by the parties. Upon termination of this
         Agreement (for any reason) each party will promptly: (i) return to the
         other party all documentation and other materials (including copies of
         original documentation or other materials) containing any confidential
         information of the other party; or (ii) certify to the other party,
         pursuant to a certificate in form and substance reasonably satisfactory
         to the other party, as to the destruction of all such documentation and
         other materials.

29.      COUNTERPARTS; FACSIMILE SIGNATURES

                  This Agreement may be executed in two or more counterparts,
         each of which shall be deemed an original, but all of which together
         shall constitute a single agreement. Each party acknowledges that a
         facsimile signature on this Agreement shall be binding upon such party.


- --------------------------------------------------------------------------------
                                       13



                                                           

EXPRESS SCRIPTS, INC.                                         CARDINAL DISTRIBUTION*
13900 RIVERPORT DRIVE                                         7000 CARDINAL PLACE
MARYLAND HEIGHTS, MISSOURI 63043                              DUBLIN, OHIO 43017
FACSIMILE: (314) 702-7120                                     FACSIMILE: (614) 757-6000

BY /s/ Barrett Toan                                           BY /s/ Robert D. Walter
  ---------------------------------------------------           ---------------------------------------------------
NAME  Barrett Toan                                            NAME  Robert D. Walter
TITLE  Chairman and CEO                                       TITLE  Chairman and CEO
DATE   7/16/01                                                DATE   7/19/01




*The term "CARDINAL  DISTRIBUTION"  will include the following  affiliated
operating  companies:  Cardinal Syracuse, Inc., a New York  corporation
(Syracuse,  New York);  James W. Daly,  Inc., a  Massachusetts  corporation
(Peabody, Massachusetts);  Ohio Valley-Clarksburg,  Inc., a Delaware corporation
(Wheeling, West Virginia); Cardinal Southeast, Inc. a Mississippi  corporation
(Madison,  Mississippi);  Whitmire Distribution  Corporation,  a Delaware
corporation (Folsom,  California);  Bindley Western Drug Company, an Indiana
corporation  (Indianapolis,  Indiana); and any other subsidiary of Cardinal
Health, Inc., an Ohio corporation ("CHI"), as may be designated by CHI.


- --------------------------------------------------------------------------------
                                       14




                                                                      EXHIBIT A

                                   PHARMACIES



Express Scripts, Inc.
14000 Riverport Drive
Maryland Heights, Missouri 63043

Express Scripts, Inc.
1700 North Desert Drive
Tempe, Arizona 85281

Express Scripts, Inc.
4500 Alexander Boulevard
Albuquerque, New Mexico 87107

Express Scripts, Inc.
3684 Marshall Lane
Bensalem, Pennsylvania 19020

Express Scripts, Inc.
433 River Street, Suite 800
Troy, New York 12180

Express Access Pharmacy, Inc.*
dba Express Scripts, Inc.
767 Electronic Drive
Horsham, Pennsylvania 19020

Express Scripts, Inc.
Specialty Distribution Service
3168 Riverport Tech Center
Maryland Heights, Missouri 63043



*This location will be subject to the terms and the conditions of this Agreement
upon termination of its existing supply agreement, which is approximately sixty
(60) days from the Commencement Date of this Agreement.



- --------------------------------------------------------------------------------
                                       15



                                                                      EXHIBIT B

                                 PRICING MATRIX

         1.       [***].  The [***] has been established based upon [***]

         (a)      [***];

         (b)      [***]($[***]); and

         (c)      [***]($[***]).

(collectively referred to herein as the [***]").  If, for any reason, [***].

         Subject to the [***] of this Agreement regarding [***](that is[***])
for [***]; provided, however, during the [***] of this Agreement, [***]%.


                                                         
         -------------------------------------------------- -------------------------------------------------
                               [***]                                             [***]
         -------------------------------------------------- -------------------------------------------------
                          $[***] - [***]                                         [***]%
         -------------------------------------------------- -------------------------------------------------
                          $[***] - [***]                                         [***]%
         -------------------------------------------------- -------------------------------------------------
                          $[***] - [***]                                         [***]%
         -------------------------------------------------- -------------------------------------------------
                          $[***] - [***]                                         [***]%
         -------------------------------------------------- -------------------------------------------------
                              $[***]                                             [***]%
         -------------------------------------------------- -------------------------------------------------



         This [***] and any [***]; provided, however, that such [***]. Any [***]
as a result of a[***] pursuant to the terms hereof shall be[***]. Any [***]
pursuant to the terms hereof shall be [***]. In all instances, [***] by this
Agreement, the [***].

         For example, [***].  If[***].  If[***].

2.       [***] of this Agreement regarding [***] (that is [***]) for[***].

3.        SPECIALLY PRICED MERCHANDISE. Notwithstanding the foregoing, the
following Merchandise will not be available for purchase in accordance with the
cost of goods set forth above, but instead will be special net billed:

         [***]
         [***]
         Certain [***]
         [***] subject to [***]
         Other [***]

4.       UP-FRONT DISCOUNT. Buyer shall be eligible to receive an up-front
discount on Buyer's purchases through Cardinal in the amount of [***] Dollars
($[***]) (the "DISCOUNT"). The


- --------------------------------------------------------------------------------
                                       16


Discount shall be payable within sixty (60) days after full execution of this
Agreement in the form of a check.

         If this Agreement is terminated prior to the end of the term, Buyer
shall repay to Cardinal, within sixty (60) days of the date of termination, a
pro rata amount (calculated based on a sixty (60) month term) of the Discount
paid to Buyer hereunder; provided, however, Buyer shall have no obligation to
repay to Cardinal any portion of the Discount if Buyer terminates this Agreement
due to Cardinal's material breach of this Agreement and failure to cure such
material breach in accordance with the terms of Section 14. The parties agree,
and Buyer acknowledges, that such payment by Buyer has been negotiated in good
faith and is not intended as a penalty.

5. [***]. During the term of this Agreement, [***]("[***]"). Cardinal [***] In
addition, [***], based upon a [***] ($[***]); provided, however, except as set
forth herein, [***] Dollars ($[***]) [***]; further provided, however, that
[***] shall be [***] In no event shall [***] Dollars ($[***]). If [***] Dollars
($[***]), [***] Dollars ($[***]), or the applicable [***] as set forth herein,
[***] For example, if during the first contract year, [***] Dollars ($[***]),
[***] Dollars ($[***]) ($[***] $[***]), or [***] Dollars ($[***])[***].

         If [***] as set forth above,[***]If [***] as set forth above during the
[***] Solely for purposes of this paragraph [***] as set forth above, [***] ,
shall be [***] (as hereinafter defined)); provided, however, in order for such
[***]

         Provided the [***] Dollars ($[***]), [***] percent ([***]) of all [***]
transactions hereunder ([***] only) ("[***]"). The [***] of the applicable[***].
All [***].

         In order to [***] the Commencement Date of this Agreement. Until [***]
of this Agreement; provided, however, if [***].

6. MEDICARE/MEDICAID DISCLOSURE. The Discount and [***] constitute a "discount
or other reduction in price," as such terms are defined under the
Medicare/Medicaid Anti-Kickback Statute, on the Merchandise purchased by Buyer
under the terms of this Agreement. Cardinal and Buyer agree to use their best
efforts to comply with any and all requirements imposed on sellers and buyers,
respectively, under 42 U.S.C. ss. 1320a-7b(b)(3)(A) and the "safe harbor"
regulations regarding discounts or other reductions in price set forth in 42
C.F.R. ss. 1001.952(h). In this regard, Buyer may have an obligation to
accurately report, as may be required, under any state or federal program which
provides cost or charge based reimbursement for the products or services covered
by this Agreement, the net cost actually paid by Buyer.

- --------------------------------------------------------------------------------
                                       17




                                                                      EXHIBIT C

                                      [***]

         During the term of this Agreement, [***] pursuant to the term and
conditions set forth below ("[***]").

[***] As a result of [***] and [***] with the terms and conditions of the [***]

                 Contract Year 1                    $[***]
                 Contract Year 2                    $[***]
                 Contract Year 3                    $[***]

                 Renewal Contract Year 4            $[***]
                 Renewal Contract Year 5            $[***]

         The [***] set forth above are based on [***] percent ([***]%) [***]
during the first contract year of this Agreement as the [***] percent ([***]%)
for contract years two (2) through five (5), [***].

         [***] in accordance with the provisions set forth below. Except as
otherwise set forth below, if, upon the completion of each contract year, [***]
set forth above, [***] as set forth below [***] ("[***]"). Any [***]

         [***] of this Agreement [***]. If this Agreement is [***] in which the
Agreement is [***], and the terms as set forth above shall be of [***].

[***] ("[***]") in accordance with the terms and conditions of this Agreement.
For purposes of the [***].

         For purposes of this Agreement, [***] as follows: [***] ([***]%) [***]
set forth below [***] as set forth herein]. The [***] Rx Products [***] or BTC
and [***]; provided, the [***] Rx Products [***] ([***]%) [***] Rx Products
[***]

         The [***] as it relates to [***], as well as [***] on the information
provided to [***] as set forth herein.

         During the term of this Agreement, [***]

         For [***], who, in turn, will [***]. Upon [***]. Upon [***] (i.e.,
[***]). If [***] as set forth above, will be included in the [***] will be as
determined by [***]

         [***]

         [***]

- --------------------------------------------------------------------------------
                                       18


         [***] ([***]%), based on the [***] or the applicable [***], for all
[***] of the following month. [***] hereunder will be included in the [***]

         Within [***] set forth above, [***] as set forth below:



                                                         
                ------------------------------------------- ------------------------------------------
                                  [***]                                       [***]
                ------------------------------------------- ------------------------------------------
                                  [***]%                                     [***]%
                ------------------------------------------- ------------------------------------------
                             [***]% - [***]%                                 [***]%
                ------------------------------------------- ------------------------------------------
                             [***]% - [***]%                                 [***]%
                ------------------------------------------- ------------------------------------------
                             [***]% - [***]%                                 [***]%
                ------------------------------------------- ------------------------------------------
                                  [***]%                                     [***]%
                ------------------------------------------- ------------------------------------------



         [***]

         [***]

- --------------------------------------------------------------------------------
                                       19



                                                                      EXHIBIT D

                                 OTHER SERVICES

HARDWARE/SOFTWARE

          [***], pursuant to the provision of Cardinal's Software License
  Agreement, [***] CardinalCHOICE(R) unit ([***]) [***] CardinalCHOICE(R)-HQ
  ([***]) Any such [***] shall remain the [***] of this Agreement, or upon [***]

         Upon termination of this Agreement for any reason, Buyer's or any
Pharmacy's rights as a licensee of the CardinalCHOICE(R), CardinalCHOICE(R)-HQ
or other Cardinal software will automatically expire, and Buyer and each
Pharmacy will promptly return such software and any hardware provided hereunder
not purchased by Buyer or any Pharmacy to a return location specified by
Cardinal.

         Cardinal will license to Buyer, pursuant to the provision of Cardinal's
Software License Agreement, its eReceiver Systems available to the Pharmacies
pursuant to Cardinal's customary terms and practices.

ON-SITE EMPLOYEE

         During the term of this Agreement, [***] employee [***] The employee
will be [***] The provision of this employee [***] and relates solely to this
Agreement. [***] such employee[***] such employee [***] During the term of this
Agreement, [***] such employee [***] such employee [***] The employee will be
[***] with this Agreement; provided, however, that such employee will [***]
employee of [***] such employee [***] the Commencement Date of this Agreement.

SPONSORSHIP OF BUYER'S OUTCOMES SEMINAR

         [***]

[***]

         [***]



- --------------------------------------------------------------------------------
                                       20



                                                                      EXHIBIT E

                   CARDINAL HEALTH RETURN GOODS AUTHORIZATION
                                ONGOING ASSURANCE

The undersigned Buyer ("BUYER") of one (1) or more of the Cardinal Health
companies identified below ("WHOLESALER," whether one (1) or more) hereby agrees
that this document is being delivered to confirm Buyer's compliance with
applicable federal, state, and local laws / guidelines concerning returned goods
and will apply to all returns by Buyer to Wholesaler from time to time and will
supersede any inconsistent provisions which may be contained in any credit
request, purchase order, or other documents pertaining to the supply
relationship between Buyer and Wholesaler.

1. Buyer represents, warrants, and guarantees to Wholesaler that: (a) each such
return will be made only to the specific Wholesaler from which the item was
originally purchased; (b) each such return will be accompanied by Wholesaler's
credit request form (the "RETURN FORM"), which will specify both Buyer's and
Wholesaler's name and address, the date of the return, the quantity and
description of the product returned, and such other information as may
reasonably be requested on Wholesaler's Return Form; (c) Buyer will retain a
copy of each Return Form and related credit memo and make such documentation
available to the manufacturer and to authorized federal, state, and local law
enforcement officers upon request; (d) the credit claimed or accepted by Buyer
for any such return will not exceed the original purchase price paid to
Wholesaler; and (e) all merchandise returned to Wholesaler has been stored and
handled by Buyer in accordance with all applicable federal, state, and local
laws, manufacturer guidelines when disclosed to Buyer by the manufacturer or
wholesaler, and good trade practices, and such merchandise has not been
adulterated or misbranded by Buyer within the meaning of the Federal Food, Drug,
and Cosmetic Act and meets all FDA, state, and other applicable requirements and
guidelines.

2. Buyer will indemnify and defend Wholesaler against and from any expense,
claim, liability, or penalty (including reasonable legal fees) arising from any
failure of Buyer to properly comply with the provisions specified in this
exhibit.

3. The term "CARDINAL HEALTH" or "WHOLESALER" will include the following
affiliated operating companies: Cardinal Syracuse, Inc., a New York corporation
(Syracuse, New York); James W. Daly, Inc., a Massachusetts corporation (Peabody,
Massachusetts); Ohio Valley-Clarksburg, Inc., a Delaware corporation (Wheeling,
West Virginia); Cardinal Southeast, Inc. a Mississippi corporation (Madison,
Mississippi); Whitmire Distribution Corporation, a Delaware corporation (Folsom,
California); Bindley Western Drug Company, an Indiana corporation (Indianapolis,
Indiana); and any other subsidiary of Cardinal Health, Inc., an Ohio corporation
("CHI"), as may be designated by CHI.



                                           EXPRESS SCRIPTS, INC.



                                           ------------------------------------
Dated:                       , 2001        By Authorized Signature / Title
      ------------------------



- --------------------------------------------------------------------------------
                                       21



                                                                      EXHIBIT E

                         ALTERNATIVE DISPUTE RESOLUTION

(a)      The parties recognize that a bona fide dispute as to certain matters
         may arise from time to time during the term of this Agreement which
         relates to either party's rights and/or obligations. To have such a
         dispute resolved by this Alternative Dispute Resolution ("ADR")
         provision, the parties first must attempt to resolve the dispute with
         the Executive Resolution Committee in accordance with Section 26 of the
         Agreement. Any negotiations regarding a dispute shall be treated as
         settlement negotiations for purposes of the Federal Rules of Evidence
         and any similar state rules of evidence. Such negotiations shall not be
         admissible in any subsequent ADR hearing. If the matter has not been
         resolved by the Executive Resolution Committee within forty-five (45)
         days of the notice of dispute, or such shorter period as set forth in
         the Agreement, or if the parties fail to meet within such forty-five
         (45) days, or such shorter period as set forth in the Agreement, either
         party may initiate an ADR proceeding as provided herein. The parties
         shall have the right to be represented by counsel in such a proceeding.

(b)      To begin an ADR proceeding, a party shall provide written notice to the
         other party of the issues to be resolved by ADR. Within fourteen (14)
         days after its receipt of such notice, the other party may, by written
         notice to the party initiating the ADR, add additional issues to be
         resolved within the same ADR.

(c)      The ADR proceeding and the resolution of any disputes in the ADR
         proceeding shall be conducted by a panel of three neutrals. Within
         twenty-one (21) days following receipt of the original ADR notice, the
         parties shall each select one neutral, and the American Arbitration
         Association shall select one neutral pursuant to the following
         procedures:

         (1)      The AAA shall submit to the parties a list of not less than
                  five (5) candidates within fourteen (14) days after receipt of
                  the original ADR notice, along with a Curriculum Vitae for
                  each candidate. No candidate shall be an employee, director,
                  or shareholder of either party or any of their subsidiaries or
                  Affiliates.

         (2)      Such list shall include a statement of disclosure by each
                  candidate of any circumstances likely to affect his or her
                  impartiality.

         (3)      Each party shall number the candidates in order of preference
                  (with the number one (1) signifying the greatest preference)
                  and shall deliver the list to the AAA within seven (7) days
                  following receipt of the list of candidates. If a party
                  believes a conflict of interest exists regarding any of the
                  candidates, that party shall provide a written explanation of
                  the conflict to the AAA along with its list showing its order
                  of preference for the candidates. Any party failing to return
                  a list of preferences on time shall be deemed to have no order
                  of preference.

         (4)      If the parties collectively have identified fewer than three
                  (3) candidates deemed to have conflicts, the AAA immediately
                  shall designate as the neutral the

- --------------------------------------------------------------------------------
                                       22


                  candidate who has no conflicts and for whom the parties
                  collectively have indicated the greatest preference. If a tie
                  should result between two candidates, the AAA may designate
                  either candidate. If the parties collectively have identified
                  three (3) or more candidates deemed to have conflicts, the AAA
                  shall review the explanations regarding conflicts and, in its
                  sole discretion, may either (I) immediately designate as the
                  neutral the candidate who has no conflicts and for whom the
                  parties collectively have indicated the greatest preference,
                  or (ii) issue a new list of not less than five (5) candidates,
                  in which case the procedures set forth in subparagraphs (c)(1)
                  - (4) shall be repeated.

(d)      No earlier than twenty-eight (28) days or later than fifty-six (56)
         days after selection, the panel of neutrals shall hold a hearing to
         resolve each of the issues identified by the parties. The ADR
         proceeding shall take place at a location, other than the principal
         place of business of either party or any of their subsidiaries or
         affiliates, as designated by the panel of neutrals.

(e)      At least seven (7) days prior to the hearing, each party shall submit
         the following to the other party and the panel of neutrals:

         (1)      a copy of all exhibits on which such party intends to rely in
                  any oral or written presentation to the panel of neutrals;

         (2)      a list of any witnesses such party intends to call at the
                  hearing, and a short summary of the anticipated testimony of
                  each witness;

         (3)      a proposed ruling on each issue to be resolved, together with
                  a request for a specific damage award or other remedy for each
                  issue. The proposed rulings and remedies shall not contain any
                  recitation of the facts or any legal arguments and shall not
                  exceed one (1) page per issue.

         (4)      a brief in support of such party's proposed rulings and
                  remedies, provided that the brief shall not exceed twenty (20)
                  pages. This page limitation shall apply regardless of the
                  number of issues raised in the ADR proceeding.

                  Except as expressly set forth in subparagraphs (e)(1) - (4),
                  no discovery shall be required or permitted by any means,
                  including depositions, interrogatories, requests for
                  admissions, or production of documents.

(f)      The hearing shall be conducted on two (2) consecutive days and shall be
         governed by the following rules:

         (1)      Each party shall be entitled to five (5) hours of hearing time
                  to present its case. The panel of neutrals shall determine
                  whether each party has had the five (5) hours to which it is
                  entitled.

- --------------------------------------------------------------------------------
                                       23


         (2)      Each party shall be entitled, but not required, to make an
                  opening statement, to present regular and rebuttal testimony,
                  documents or other evidence, to cross-examine witnesses, and
                  to make a closing argument. Cross-examination of witnesses
                  shall occur immediately after their direct testimony, and
                  cross-examination time shall be charged against the party
                  conducting the cross-examination.

         (3)      The party initiating the ADR shall begin the hearing and, if
                  it chooses to make an opening statement, shall address not
                  only issues it raised but also any issues raised by the
                  responding party. The responding party, if it chooses to make
                  an opening statement, also shall address all issues raised in
                  the ADR. Thereafter, the presentation of regular and rebuttal
                  testimony and documents, other evidence, and closing arguments
                  shall proceed in the same sequence.

         (4)      Except when testifying, witnesses shall be excluded from the
                  hearing until closing arguments.

         (5)      Settlement negotiations shall not be admissible under any
                  circumstances. Affidavits prepared for purposes of the ADR
                  hearing also shall not be admissible. As to all other matters,
                  the panel of neutrals shall have sole discretion regarding the
                  admissibility of any evidence.

(g)      Within seven (7) days following completion of the hearing, each party
         may submit to the other party and the panel of neutrals a post-hearing
         brief in support of its proposed rulings and remedies, provided that
         such brief shall not contain or discuss any new evidence and shall not
         exceed ten (10) pages. This page limitation shall apply regardless of
         the number of issues raised in the ADR proceeding.

(h)      The panel of neutrals shall rule on each disputed issue within fourteen
         (14) days following completion of the hearing. Such ruling shall adopt
         in its entirety the proposed ruling and remedy of one of the parties on
         each disputed issue but may adopt one party's proposed rulings and
         remedies on some issues and the other party's proposed rulings and
         remedies on other issues. The panel of neutrals shall not issue any
         written opinion or otherwise explain the basis of the ruling.

(i)      The panel of neutrals shall be paid a reasonable fee plus expenses.
         These fees and expenses, along with the reasonable legal fees and
         expenses of the prevailing party (including all expert witness fees and
         expenses), the fees and expenses of a court reporter, and any expenses
         for a hearing room, shall be paid as follows:

         (1)      If the panel of neutrals rules in favor of one party on all
                  disputed issues in the ADR, the losing party shall pay 100% of
                  such fees and expenses.

         (2)      If the panel of neutrals rules in favor of one party on some
                  issues and the other party on other issues, the panel of
                  neutrals shall issue with the rulings a written determination
                  as to how such fees and expenses shall be allocated between


- --------------------------------------------------------------------------------
                                       24


                  the parties. The panel of neutrals shall allocate fees and
                  expenses in a way that bears a reasonable relationship to the
                  outcome of the ADR, with the party prevailing on more issues,
                  or on issues of greater value or gravity, recovering a
                  relatively larger share of its legal fees and expenses.

(j)      The rulings of the panel of neutrals and the allocation of fees and
         expenses shall be binding, non-reviewable, and non-appealable, and may
         be entered as a final judgment in any court having jurisdiction.

(k) Except as provided in paragraph (j) or as required by law, the existence of
the dispute, any settlement negotiations, the ADR hearing, any submissions
(including exhibits, testimony, proposed rulings, and briefs), and the rulings
shall be deemed Confidential Information. The panel of neutrals shall have the
authority to impose sanctions for unauthorized disclosure of Confidential
Information.

(l)      Except as otherwise set forth herein the ADR proceedings shall be
         governed in accordance with the AAA rules.

(m)      All references to days in this Exhibit F shall mean calendar days.


- --------------------------------------------------------------------------------
                                       25





                               FIRST AMENDMENT TO
                             PRIME VENDOR AGREEMENT

         THIS FIRST AMENDMENT TO PRIME VENDOR AGREEMENT ("FIRST AMENDMENT") is
among Cardinal Distribution* ("CARDINAL"), and Express Scripts, Inc. ("BUYER").

         WHEREAS, Cardinal and Buyer executed a Prime Vendor Agreement, dated
July 1, 2001 (the "AGREEMENT").

         WHEREAS, Buyer desires to discontinue purchasing certain [***] Products
directly from the applicable manufacturers and/or suppliers and commence
purchasing such [***] Products through Cardinal.

         WHEREAS, the parties now desire to amend the Agreement as set forth
below.

         NOW THEREFORE, in consideration of the foregoing recitals, the parties
hereby agree as follows:

         1. SECTION 2, SALE OF MERCHANDISE. The definition of "PRIMARY WHOLESALE
REQUIREMENTS" shall be deleted in its entirety and replaced with the following:
"The term `PRIMARY REQUIREMENTS' means that Buyer will purchase for each
Pharmacy [***] of its requirements of [***] Products that are available from
Cardinal from Cardinal. If Cardinal notifies Buyer (such notice to be provided
at the time of order confirmation) that it will be unable to supply any
[***]Product within forty-eight (48) hours of Buyer's order of such [***]
Product, Buyer may purchase such [***] Product from another supplier, including,
but not limited to alternate source vendors, and such purchases shall be
included in the calculations of Buyer's Qualified Annual and Monthly Purchases
for the purpose of determining Buyer's compliance with the Minimum Requirements
(as hereinafter defined) and Buyer's applicable cost of goods; provided,
however, Buyer shall provide to Cardinal reasonable documentation of the [***]
Products purchased from other suppliers and that Buyer attempted to purchase
such [***] Products from Cardinal and they were unavailable within forty-eight
(48) hours." Further, all references to the term "PRIMARY WHOLESALE
REQUIREMENTS" in the Agreement shall be deleted and replaced with the term
"PRIMARY REQUIREMENTS".

         The following paragraph shall be deleted from Section 2, Sale of
Merchandise: "Cardinal acknowledges that Buyer, [***]."

         2. SECTION 3, PURCHASE PRICE. The last paragraph of Section 3, Purchase
Price, shall be deleted in its entirety and replaced with the following: "All
[***] CardinalCHOICE(R)pharmacy system [***] the pricing specified in the
Pricing Matrix; provided, however, [***]

         3. SECTION 4, [***] AND SAVINGS AND EXHIBIT C. Section 4, [***] and
Savings, and Exhibit C, [***] and Related Savings, shall be deleted in their
entirety.

- --------------------------------------------------------------------------------
                                       26


         4. SECTION 5, PAYMENT TERMS. The following additional payment terms
shall be added to Section 5(a)(i) for Direct Store Delivery Purchases:

         (a) [***] Buyer will cause Cardinal to receive payment in full by [***]
of the amount due for all Merchandise delivered and services provided during the
[***]

         (b) [***] Buyer will cause Cardinal to receive payment in full: (1) by
not later than the [***] day of each calendar month of the amount due for all
Merchandise delivered and services provided during the first (1st) [***] days of
such calendar month; (2) by not later than the [***] day of each calendar month,
of the amount due for all Merchandise delivered and services provided during the
[***] through the [***] day of such calendar month; and (3) by not later than
the [***] day of each calendar month, of the amount due for all Merchandise
delivered and services provided during the period beginning on the [***] day of
the preceding calendar month and ending on the last day of such preceding
calendar month.

         Sections 5(a)(ii) and (iii) shall be deleted in their entirety.

         5. SECTION 6, ORDERING AND DELIVERY. The third sentence of Section 6,
Ordering and Delivery, shall be amended to add the Pharmacies located in
Bensalem, Pennsylvania; East Hanover, New Jersey; and Harrisburg, Pennsylvania.

         In addition, the fourth sentence shall be deleted in its entirety and
replaced with the following: "Buyer will incur a separate delivery charge, not
to exceed Cardinal's actual cost for courier delivery, for additional deliveries
(beyond [***] )."

         6. EXHIBIT B, PRICING MATRIX. Section 1 of Exhibit B, Pricing Matrix,
shall be deleted in its entirety and replaced with Section 1 of Exhibit A
attached to this Amendment.

         Section 2, Brokerage Purchases, of Exhibit B, Pricing Matrix, shall be
deleted in its entirety.

         Section 5, Generic Outsource Program Rebate, of Exhibit B, Pricing
Matrix, shall be deleted in its entirety.

         7. EXHIBIT D, OTHER SERVICES. The paragraph titled, [***], shall be
deleted in its entirety from Exhibit D, Other Services.

         8. SECTION 12, SERVICE LEVEL. Section 12, Service Level, shall be
deleted in its entirety and replaced with the following:

         "Cardinal will exercise all reasonable efforts to provide [***]
         (excluding Buyer's Top [***] Items (as hereinafter defined)) [***]
         ([***]%) [***] in accordance with the standards and procedures
         specified in AMENDMENT EXHIBIT B attached hereto. For Buyer's Top [***]
         Items, Cardinal will exercise all reasonable efforts to provide each
         Pharmacy with an average monthly service level of at least [***]
         ([***]%) calculated quarterly (calendar) in accordance with the
         standards and procedures specified in AMENDMENT EXHIBIT B attached
         hereto.

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                                       27


         Buyer's "Top [***] Items" means the top [***]Rx Products purchased by
         Buyer based on Rx count. Buyer will provide to Cardinal a report of the
         "Top [***] Items" on a quarterly (calendar) basis for purposes of
         measuring the service level on such items the following calendar
         quarter. [***] ([***]%) [***] ([***]%) [***] ([***]%) [***] ([***]%)
         [***] ([***]%), [***]. For example, [***] $[***] % [***] $ [***]
         ([***]) [***]% - [***]% = [***] % and ([***]) [***]% x $[***] x [***]%
         = $[***].

         Notwithstanding [***] in accordance with the standards and procedures
     specified in AMENDMENT EXHIBIT B attached hereto is [***] ([***]%) [***]
     ([***]%) [***] as set forth above) [***] ([***]%) [***] ([***]%) [***]."

         9. EXHIBIT A, PHARMACIES. Exhibit A is hereby amended to add the
following additional Pharmacies:

         Central Fill, Inc.
         4415 Lewis Road
         Harrisburg, Pennsylvania 17111

         Central Fill, Inc.
         721 Ridgedale Avenue
         East Hanover, New Jersey 07936

         ESI Mail Pharmacy Service, Inc.
         7909 South Hardy
         Tempe, Arizona 85284

         10. MISCELLANEOUS. Capitalized terms not defined herein will have the
same meaning ascribed to them in the Agreement, it being the intent of the
parties that the Agreement and this First Amendment will be applied and
construed as a single instrument. The Agreement, as modified by this First
Amendment, constitutes the entire agreement between Cardinal and Buyer regarding
the subject matter of the Agreement and this First Amendment and supersedes all
prior or contemporaneous writings and understandings between the parties
regarding the same. This First Amendment will be binding upon the parties, their
heirs, legal representatives, successors and assigns. The terms and provisions
of this First Amendment are severable. If any term or provision of this First
Amendment is determined to be illegal or unenforceable by a court of competent
jurisdiction, the remaining terms and provisions of this First Amendment and the
Agreement will remain in full force and effect. This First Amendment may only be
amended in a writing signed by Cardinal and Buyer.

         11. EFFECTIVE DATE. This First Amendment shall be effective as of the
date of full execution ("EFFECTIVE Date"). Except as otherwise amended herein,
the terms and conditions of the Restated Agreement shall remain in full force
and effect.


CARDINAL DISTRIBUTION*                      EXPRESS SCRIPTS, INC.

                                                  
BY:  /s/ Mark Parrish                                 BY:  /s/ George Paz
    --------------------------                            ------------------------------


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                                       28



                                                  
NAME:   Mark Parrish                                 NAME:    George Paz
TITLE:  President                                    TITLE:   CFO
DATE:   1/15/03                                      DATE:    1/9/03



*The term "Cardinal Distribution" shall include the following affiliated
operating companies: James W. Daly, Inc., a Massachusetts corporation (Peabody,
Massachusetts) (now known as "Cardinal Health 106, Inc."); Cardinal Southeast,
Inc. a Mississippi corporation (Madison, Mississippi) (now known as "Cardinal
Health 103, Inc."); Whitmire Distribution Corporation, a Delaware corporation
(Folsom, California) (now known as "Cardinal Health 110, Inc."); Bindley Western
Industries, Inc., a Indiana corporation (Indianapolis, Indiana) (now known as
"Cardinal Health 100, Inc."); and any other subsidiary of Cardinal Health, Inc.,
an Ohio corporation ("CHI"), as may be designated by CHI.

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                                       29





                                                                      EXHIBIT A

1.       [***].  The [***] has been established based upon [***]:

(a)      [***];

(b)      [***] Dollars ($[***]); and

(c)      [***] Dollars ($[***]).

(collectively referred to herein as the [***]. If, for any reason, [***] Dollars
($[***]) [***] beginning on the Commencement Date of this Agreement

      Subject to the [***] of this Agreement regarding [***] (that is [***]) for
[***]; provided, however, until all Pharmacies are converted to purchasing their
Primary Requirements from Cardinal, the applicable price for the Harrisburg, PA,
East Hanover, NJ and Specialty Distribution Service (Maryland Heights, MO)
Pharmacies will be equal to [***] (as defined in the Agreement) [***] provided,
however, conversion of all Pharmacies shall be completed within six (6) months
following the first day of the conversion of the first Pharmacy. The remaining
Pharmacies will continue to purchase at their current pricing until converted,
at which time they will move to the [***]


                                                                                        
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                      [***]                                [***]                  [***]                 [***]
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                           [***]%                [***]%                 [***]%
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                           [***]%                [***]%                 [***]%
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                           [***]%                [***]%                 [***]%
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                           [***]%                [***]%                 [***]%
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                           [***]%                [***]%                 [***]%
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                           [***]%                [***]%                 [***]%
- --------------------------------------------------- --------------------- ---------------------- ---------------------
                  $[***] - [***]                                                  [***]
- --------------------------------------------------- --------------------- ---------------------- ---------------------


         Upon completion of the conversion of all Pharmacies or achievement of
at least [***] Dollars ($[***]) in total [***], whichever is earlier, the next
[***] will be annualized to determine the applicable pricing tier for all fully
converted Pharmacies. Such pricing will be effective on the [***] of the next
[***]. For example, if all conversions are completed in [***] to determine the
applicable price beginning on [***]. Such pricing will continue until a full
[***] can be reviewed. The pricing will be adjusted on the [***] of the [***].
For example, [***] for [***] will be reviewed with the next [***]. Thereafter,
[***] will be reviewed on a [***] basis and any [***] based on [***] days during
such [***]; provided, however, that such [***] of the [***]. In all instances,
[***]. For example, [***].

         The pricing set forth on this Exhibit A [***] (as hereinafter defined)
[***] that include, but are not limited to, [***] In the event that [***] during
the term of this Agreement [***] or in the event that [***], then [***] In such
event, [***]. If the [***]; provided, however, [***] shall be [***].

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                                       30





                                                            AMENDMENT EXHIBIT B

                            SERVICE LEVEL DEFINITION

         For purposes of this Agreement, the service level percentage will be
calculated by dividing total lines of Rx Products shipped by the number of lines
of Rx Products ordered. The following items will be excluded from the service
level calculation:

         1.       [***]
         2.       [***] items [***];
         3.       [***];
         4.       Items where a Facility has [***];
         5.       Items where a Facility's [***]; and
         6.       [***] item [***].

         The service level for each Pharmacy will commence fourteen days (14)
days following the later of such Pharmacy's initial order of Merchandise under
this Amendment from Cardinal or Cardinal's receipt of accurate usage data from
such Pharmacy. The service level for Facilities added to this Agreement after
the Commencement Date will commence fourteen (14) days following receipt by
Cardinal of accurate usage data. This will allow Cardinal to gain usage
information and adjust inventory levels appropriately.

         Upon Buyer's request, if Cardinal does not meet its service level for
any quarter, Cardinal and Buyer will jointly develop a service level action plan
for the following quarter.

         Buyer will notify Cardinal at least forty-five (45) days prior to the
expiration of any manufacturer's contract which is being replaced with a
different contract, and will cooperate with and assist Cardinal in disposing of
any excess inventory of Merchandise previously stocked at Buyer's or a
Facility's request. Failure to comply with these notice requirements will
entitle Cardinal to discontinue the service level to the Facilities until ninety
(90) days after delivery of accurate usage data for the new items.

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                                       31