Exhibit 99.03

                                 FIRST AMENDMENT
                                     TO THE
                         CARDINAL HEALTH PROFIT SHARING,
                           RETIREMENT AND SAVINGS PLAN
               (AMENDED AND RESTATED EFFECTIVE AS OF JULY 1, 1998)
                              (REVISED AS OF 2002)

                             BACKGROUND INFORMATION

A.       Cardinal Health, Inc., an Ohio corporation (the "Corporation"),
         maintains a profit sharing plan known as the Cardinal Health Profit
         Sharing, Retirement and Savings Plan (the "Plan") for the benefit of
         its employees and their beneficiaries.

B.       Pursuant to Section 13.02 of the Plan, the Corporation may amend the
         Plan at any time.

C.       The Cardinal Health Profit Sharing, Retirement and Savings Plan
         Committee (the "Committee") assists in the administration of the Plan
         and is empowered to amend the Plan on behalf of the Corporation by
         action of a majority of its members then in office.

D.       The Committee desires to amend the Plan to clarify the appropriate
         effective date for the change in the definition of the "Required
         Beginning Date" pursuant Section 401(a)(9) of the Internal Revenue Code
         of 1986, as amended (the "Code") in order to satisfy the review of the
         Plan by the Internal Revenue Service for a favorable determination.

                              AMENDMENT TO THE PLAN

1.       A new Section 3.11.C. is hereby added to the Plan to read as follows:

         Coordination of Excess Elective Deferrals and Excess Compensation
         Deferrals. In accordance with Treas. Reg. Section 1.401(k)-1(f)(5)(i),
         the amount of Excess Compensation Deferrals to be distributed or
         re-characterized shall be reduced by Excess Elective Deferrals
         previously distributed for the taxable year ending in the same Plan
         Year and Excess Elective Deferrals shall be reduced by Excess
         Compensation Deferrals previously distributed or re-characterized for
         the Plan Year beginning in such taxable year.

2. The definition of "Required Beginning Date" in Section 6.03.B. of the Plan
shall be amended to add the introductory phrase "On and after January 1, 1999,"
to the first sentence of such section.

3. All other provisions of the Plan shall remain in full force and effect.


Dated October 20, 2003.                    CARDINAL HEALTH, INC.


                                           By: /s/ Susan Nelson
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                                           Its:
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