EXHIBIT 99.04

                                 FIRST AMENDMENT
                                     TO THE
                         CARDINAL HEALTH PROFIT SHARING,
                           RETIREMENT AND SAVINGS PLAN
                     (As amended and restated July 1, 2002)


                             BACKGROUND INFORMATION

A.       Cardinal Health, Inc. ("Cardinal Health") established and maintains the
         Cardinal Health Profit Sharing, Retirement and Savings Plan (the
         "Plan") for the benefit of participants and their beneficiaries.

B.       The Cardinal Health, Inc. Employee Benefits Policy Committee (the
         "Committee") oversees the administration of the Plan and is authorized
         to amend the Plan.

C.       The Committee desires to amend the Plan to reflect (1) use of
         forfeiture amounts from a current plan year to fund contributions
         attributable to a prior or future plan year; (2) changes to the
         provisions relating to participant direction of investments; (3)
         certain recent corporate acquisitions, which will become participating
         employers; (4) the merger of certain acquired plans with and into the
         Cardinal Health Plan; and (5) special eligibility, full vesting and
         additional employer contributions to former employees of Cardinal
         Health 409, Inc. whose employment with Cardinal Health was terminated
         as part of the divestiture of the paintball manufacturing division.

D.       Section 13.02 of the Plan permits the amendment of the Plan at any
         time.

                              AMENDMENT OF THE PLAN

1.       Section 3.17 of the Plan is hereby amended in its entirety to read as
         follows:

         Section 3.17 ALLOCATION OF FORFEITURES. Subject to any restoration
         allocation required under Section 5.05, the Committee shall allocate
         and use all or a portion of the amount of a Participant's benefit
         forfeited under the Plan either to pay reasonable expenses of the Plan
         (to the extent not paid by the Employer) or to reduce its Profit
         Sharing Contribution, Special Contribution, Matching Contribution
         and/or other contributions payable under the Plan for the Plan Year in
         which the forfeiture occurs or any prior or future Plan Year, as
         determined by the Committee.

2.       Section 9.05 of the Plan is hereby amended in its entirety to read as
         follows:

         Section 9.05. PARTICIPANT DIRECTION OF INVESTMENT. The Committee and
         the Trustee shall establish rules governing the administration of
         Investment Funds and procedures for Participant direction of
         investment, including rules governing the timing, frequency and manner
         of making investment elections. The Committee and the Employer reserve
         the right to change the investment options available under the Plan and
         rules governing investment designations from time to time. Nothing in
         this or any other







         provision of the Plan shall require the Trustee, the Employer or the
         Committee to implement Participant investment directions or changes in
         such directions, or to establish any procedures, other than on an
         administratively practicable basis, as determined by the Employer in
         its discretion.

         Each Participant shall, in accordance with procedures established by
         the Committee and the Trustee, direct that his Account and
         contributions thereto be invested and reinvested in any one or more of
         the Investment Funds. The investment of any such monies shall be
         subject to such restrictions as the Committee may determine, in its
         sole discretion, to be advisable or necessary under the circumstances.
         Moreover, in accordance with procedures established by the Trustee and
         agreed to by the Committee, Participants may, when administratively
         practicable, be permitted to change their current and prospective
         investment designations through telephone, "on-line" or similar
         instructions to the Trustee or its authorized agent on a frequency
         established under such procedures, as in effect from time to time.

         The exercise of investment direction by a Participant will not cause
         the Participant to be a fiduciary solely by reason of such exercise,
         and neither the Trustee nor any other fiduciary of this Plan will be
         liable for any loss or any breach that results from the exercise of
         investment direction by the Participant. The investment designation
         procedures established under the Plan shall be and are intended to be
         in compliance with the requirements of ERISA Section 404(c) and the
         regulations thereunder.

         In no event shall Participants be permitted to direct that such
         Accounts and/or such additional contributions be invested in the
         Employer Common Stock Fund until Cardinal Health, Inc., the Plan, the
         Trustee and all other relevant parties have fully complied with such
         requirements, including, but not limited to, federal and state
         securities laws, as the Committee has determined to be applicable. The
         Committee may restrict the ability of any person covered under Section
         16 of the Securities Exchange Act of 1934, as amended, or any other
         corporate insider of the Employer to direct the investment of his
         Account in the Employer Common Stock Fund. Notwithstanding any
         provision to the contrary, the Committee may, in its sole discretion
         and where the terms of any relevant investment contracts, regulated
         investment companies or pooled or group trusts so require, impose
         special terms, conditions and restrictions upon a Participant's right
         to direct the investment in, or transfer into or out of, such
         contracts, companies or trusts.

3.       Section 9.06 of the Plan is amended in its entirety to read as follows:

         Section 9.06. CHANGE OF INVESTMENT DESIGNATIONS. Each Participant who
         is entitled to direct the investment of additional contributions to be
         allocated to his Account in accordance with Section 9.05 hereof may
         select how such additional contributions are to be invested. Such
         investment directions shall be made in accordance with applicable rules
         or procedures established by the Trustee and the Committee.

         Each Participant may prospectively re-elect how those amounts then held
         in his Account are to be reinvested in the various Investment Funds
         until otherwise changed or modified. Such investment directions shall
         be made in accordance with applicable rules or procedures established
         by the Trustee and the Committee.







         Notwithstanding the foregoing to the contrary, the Committee may, in
         its sole discretion and where the terms of any relevant investment
         contracts, regulated investment companies or pooled or group trusts so
         require, or where ERISA fiduciary obligations and considerations so
         merit, impose special terms, conditions and restrictions upon a
         Participant's right to direct the investment in, or transfer into or
         out of, such contracts, companies or trusts. In addition, with respect
         to Shares held under the Plan that were previously maintained under the
         Owen Healthcare, Inc. Employee Stock Ownership Plan (the "ESOP
         Shares"), no more than 25% of the original number of ESOP Shares of any
         Participant transferred to this Plan may be exchanged, sold or
         distributed in any calendar quarter. This restriction on the
         disposition of ESOP Shares shall expire on July 1, 2001.

4.       Schedule II to the Plan, Schedule of Merging Plans, is hereby amended
         by the addition of the following merging plans as of the dates to be
         determined by the Corporate Benefits Department of Cardinal Health.

         Beckloff Associates, Inc. 401(k) Profit Sharing Plan
         Snowden Pencer Inc. 401(k) Profit Sharing Plan

5.       Appendix A to the Plan, Participating Employers, is hereby amended by
         the addition of the following participating employers (in appropriate
         alphabetical order) as of the dates set forth herein.

<Table>
                                                           
         Beckloff Associates, LLC                             July 1, 2004
         Medicap Pharmacies Incorporated                      July 1, 2004
         Snowden Pencer, Inc.                                 July 1, 2004
</Table>

6.       A new Appendix N is hereby added to the Plan to reflect special
         eligibility, vesting and contributions for former employees of Cardinal
         Health 409, Inc. whose employment was terminated as a result of the
         divestiture of the paintball manufacturing division in the form
         attached to this Second Amendment as Exhibit A.

7.       All other provisions of the Plan shall remain in full force and effect.


                                    CARDINAL HEALTH, INC.


                                    By:   /s/ Susan Nelson
                                          --------------------------------------
                                          Susan Nelson, Vice President, Benefits

                                    Date: 5/25/04
                                          --------------------------------------