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     As filed with the Securities and Exchange Commission on March 7, 1994

                                                       Registration No. 33-
==============================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                              
                              --------------------
                                    
                                    FORM S-8
                             REGISTRATION STATEMENT
                                     Under
                           The Securities Act of 1933

                              --------------------
                             
                             CARDINAL HEALTH, INC.
                (formerly known as Cardinal Distribution, Inc.)
             (Exact name of registrant as specified in its charter)

                Ohio                                 31-0958666
(State or other jurisdiction of                   (I.R.S. Employer
incorporation or organization)                  Identification No.)

655 Metro Place South, Suite 925, Dublin, Ohio           43017
    (Address of Principal Executive Offices)           (Zip Code)
                              
                              --------------------

                             CARDINAL HEALTH, INC.
                              STOCK INCENTIVE PLAN
                            (Full title of the plan)

                              --------------------
                            
                            George H. Bennett, Jr.,
                  Executive Vice President and General Counsel
                             Cardinal Health, Inc.
                        655 Metro Place South, Suite 925
                               Dublin, Ohio 43017
                    (Name and address of agent for service)

                                 (614) 761-8700
         (Telephone number, including area code, of agent for service)

                              --------------------
                        

                        CALCULATION OF REGISTRATION FEE

================================================================================================================
Title of             Amount                Proposed                 Proposed                  Amount of
securities to        to be                 maximum offering         maximum aggregate         registration
be registered        registered(1)         price per share          offering price(2)         fee               
- ----------------------------------------------------------------------------------------------------------------
                                                                                  
Common Shares,
without par
value                1,328,125             $ 48.50                   $ 64,414,062.50           $ 22,211.90
================================================================================================================
<FN>
(1)      Also includes an indeterminable number of additional shares that may
         become issuable pursuant to the anti-dilution provisions of the Plan.

(2)      Estimated in accordance with Rule 457 solely for the purpose of
         determining the registration fee, based on the average of the high and
         low reported sale prices on February 28, 1994, of the registrant's Common
         Shares as reported on the NASDAQ National Market System.


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                                    PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

         The Common Shares registered by Cardinal Health, Inc. (the "Company")
pursuant to this Registration Statement will be issued under the Company's
Stock Incentive Plan (the "Plan").

         In Registration Statement on Form S-8, as amended (No. 33-20895) and
Registration Statement on Form S-8 (No. 33-38022), the Company previously
registered an aggregate of 1,171,875 Common Shares for issuance under the Plan,
in each case as subsequently adjusted for stock splits and stock dividends.
The contents of such Registration Statements are incorporated by reference
herein.

Item 5.  Interests of Named Experts and Counsel.

         The legality of the Common Shares offered hereby has been passed upon
for the Company by Baker & Hostetler, Cleveland, Ohio.  Michael E. Moritz, a
director and Secretary of the Company, is a partner of Baker & Hostetler and,
as of February 28, 1994, was the beneficial owner of 457,229 Common Shares.


Item 8.  Exhibits.


Exhibit Number                    Description of Exhibit
- --------------                    ----------------------

                               
     5                            Opinion of Baker & Hostetler as to legality of the Common Shares being registered

    23(a)                         Consent of Deloitte & Touche

    23(b)                         Consent of Arthur Andersen & Co.

    23(c)                         Consent of Baker & Hostetler (included in Opinion filed as Exhibit 5 hereto)






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                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-8 and has duly caused this
registration statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Dublin, State of Ohio, on the 7th day of
March, 1994.

                                CARDINAL HEALTH, INC.

                                By: /s/ Robert D. Walter
                                    ---------------------------------
                                    Robert D. Walter, Chairman and Chief
                                    Executive Officer


         KNOW ALL MEN BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints Robert D. Walter, George H.  Bennett,
Jr., and Michael E. Moritz, and each of them, severally, as his
attorney-in-fact and agent, with full power of substitution and resubstitution,
for him and in his name, place, and stead, in any and all capacities, to sign
any and all pre- or post-effective amendments to this Registration Statement,
and to file the same with all exhibits hereto, and other documents in
connection therewith, with the Securities and Exchange Commission,
granting unto said attorney-in-fact and agent, and each of them, full power and
authority to do and perform each and every act and thing requisite or necessary
to be done in and about the premises, as fully to all intents and purposes as
he might or could do in person, hereby ratifying and confirming all that said
attorneys-in-fact and agents, or any of them, or their or his substitutes may
lawfully do or cause to be done by virtue hereof.

         Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities indicated on the 7th day of March, 1994.




   Signature                                                       Title
   ---------                                                       -----
                                               
/s/Robert D. Walter                               Chairman and Chief Executive
- --------------------------------------------      Officer (principal executive officer)                            
Robert D. Walter                                  
                                            

/s/David Bearman                                  Executive Vice President and Chief
- --------------------------------------------      Financial Officer (principal financial officer and          
David Bearman                                     principal accounting officer)
                                              
                                            
/s/Mitchell J. Blutt, M.D.                        Director
- --------------------------------------------              
Mitchell J. Blutt, M.D.                     

                                            
/s/John F. Finn                                   Director
- --------------------------------------------              
John F. Finn                                

                                            
/s/Robert L. Gerbig                               Director
- --------------------------------------------              
Robert L. Gerbig                            






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/s/Michael S. Gross                                Director
- --------------------------------------------               
Michael S. Gross                            
                                            

/s/John F. Havens                                  Director
- --------------------------------------------               
John F. Havens                              

                                            
/s/John C. Kane                                    Director
- --------------------------------------------               
John C. Kane                                

                                            
/s/James L. Heskett                                Director
- --------------------------------------------               
James L. Heskett                            

                                            
/s/George R. Manser                                Director
- --------------------------------------------               
George R. Manser                            

                                            
/s/John B. McCoy                                   Director
- --------------------------------------------               
John B. McCoy                               

                                            
/s/Michael E. Moritz                               Director
- --------------------------------------------               
Michael E. Moritz                           

                                            
/s/Jerry E. Robertson                              Director
- --------------------------------------------               
Jerry E. Robertson                          

                                            
/s/L. Jack Van Fossen                              Director
- --------------------------------------------               
L. Jack Van Fossen                          

                                            
/s/Melburne G. Whitmire                           Director
- --------------------------------------------               
Melburne G. Whitmire                        
                                    





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                                 EXHIBIT INDEX

         
EXHIBIT           
NUMBER                        EXHIBIT DESCRIPTION
- ------                        -------------------
                           
5                             Opinion of Baker & Hostetler as to legality of
                              the Common Shares being registered
                  
23(a)                         Consent of Deloitte & Touche
                  
23(b)                         Consent of Arthur Andersen & Co.
                  
23(c)                         Consent of Baker & Hostetler (included in
                              Opinion filed as Exhibit 5 hereto)