1



                                                                    Exhibit 24.1

                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
Corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the annual report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the state of ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 26th day of
January, 1998.




                                              /S/ MELVIN D. BOOTH
                                              ----------------------------------
                                              Melvin D. Booth



   2



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this ____ day of
_____________, 1998.




                                            /s/ JOHN S. CHRISTIE
                                            ------------------------------------
                                            John S. Christie






   3



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 27th day of
January, 1998.




                                             /s/ C. MICHAEL HAZARD
                                             -----------------------------------
                                             C. Michael Hazard


   4



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 26th day of
January, 1998.




                                        /s/ JULIUS R. KREVANS
                                        ----------------------------------------
                                        Dr. Julius R. Krevans




   5



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 29th day of
January, 1998.




                                        /s/ MICHAEL P. MOORE
                                        ----------------------------------------
                                        Dr. Michael P. Moore


   6



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 26th day of
January, 1998.



          
                                         /s/ JOHN SCHROEPFER
                                         ---------------------------------------
                                         John Schroepfer



   7



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint David C. Bupp to be his agent and
attorney-in-fact;

With the power to act fully hereunder and with full power of substitution to act
in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which he
shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

The agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this _______ day of
__________ , 1998.




          
                                        /s/ JOHN L. RIDIHALGH
                                        ----------------------------------------
                                        John L. Ridihalgh



   8



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 27th day of
January, 1998.




                                             /s/ J. FRANK WHITLEY, JR.
                                             -----------------------------------
                                             J. Frank Whitley, Jr.



   9



                                POWER OF ATTORNEY



The undersigned who is a director or officer of Neoprobe Corporation, a Delaware
corporation (the "Company");

Does hereby constitute and appoint John L. Ridihalgh and David C. Bupp to be his
agents and attorneys-in-fact;

Each with the power to act fully hereunder without the other and with full power
of substitution to act in the name and on behalf of the undersigned;

To sign and file with the Securities and Exchange Commission the Annual Report
of the Company on Form 10-K and any amendments or supplements to such Annual
Report; and

To execute and deliver any instruments, certificates or other documents which
they shall deem necessary or proper in connection with the filing of such Annual
Report, and generally to act for and in the name of the undersigned with respect
to such filings as fully as could the undersigned if then personally present and
acting.

Each agent named above is hereby empowered to determine in his discretion the
times when, the purposes for, and the names in which, any power conferred upon
him herein shall be exercised and the terms and conditions of any instrument,
certificate or document which may be executed by him pursuant to this
instrument.

This Power of Attorney shall not be affected by the disability of the
undersigned or the lapse of time.

The validity, terms and enforcement of this Power of Attorney shall be governed
by those laws of the State of Ohio that apply to instruments negotiated,
executed, delivered and performed solely within the State of Ohio.

This Power of Attorney may be executed in any number of counterparts, each of
which shall have the same effect as if it were the original instrument and all
of which shall constitute one and the same instrument.

IN WITNESS WHEREOF, I have executed this Power of Attorney this 2nd day of
February, 1998.




                                                 /s/ JAMES F. ZID
                                                 -------------------------------
                                                 James F. Zid