1

                                                                     Exhibit 4.1


                       AMENDMENT NO. 2 TO CREDIT AGREEMENT


         This Amendment No. 2 (the "Amendment") is entered into as of December
21, 1998 by and among OMNICARE, INC., a Delaware corporation (the "Borrower"),
the undersigned lenders (collectively, the "Lenders") and THE FIRST NATIONAL
BANK OF CHICAGO, as one of the Lenders and in its capacity as contractual
representative (the "Agent") on behalf of itself and the other Lenders.

                                    RECITALS:

         WHEREAS, the Borrower, the Lenders and the Agent have entered into that
certain Credit Agreement dated as of October 22, 1996, as amended by an
Amendment No. 1 dated as of November 3, 1997 (the "Credit Agreement");

         WHEREAS, the Borrower has notified the Lenders and the Agent that the
Borrower wishes to enter into a $400,000,000 364-day revolving credit facility
with certain other lenders and the Agent, as agent for such other lenders (the
"364-Day Facility"), which facility would be guaranteed by certain of the
Subsidiaries of the Borrower (the "Related Guaranties");

         WHEREAS, the Borrower seeks to amend the Credit Agreement to permit the
364-Day Facility and the Related Guaranties; and

         WHEREAS, the Required Lenders and the Agent are willing to amend the
Credit Agreement to permit the 364-Day Facility and the Related Guaranties on
the terms and conditions herein set forth;

         NOW, THEREFORE, for good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto hereby agree as
follows:

         1. DEFINED TERMS. Capitalized terms used herein and not otherwise
defined herein shall have the meanings attributed to such terms in the Credit
Agreement.

         2. AMENDMENTS TO CREDIT AGREEMENT. Upon the effectiveness of this
Amendment in accordance with the provisions of SECTION 3 below, the Credit
Agreement is hereby amended as follows:

                  (a) Section 1.1 of the Credit Agreement is hereby amended by
         deleting therefrom the definition of "APPLICABLE COMMITMENT FEE RATE"
         and substituting therefor the following:

                           "APPLICABLE COMMITMENT FEE RATE" means, for any date,
                  the applicable per annum Commitment Fee Rate set forth below
                  based on the Fixed Charge Coverage Ratio as of the last day of
                  the Borrower's most recently ended fiscal quarter for the four
                  consecutive fiscal quarters ending with such fiscal quarter:




                                                                                     Applicable
                           Fixed Charge Coverage Ratio                          Commitment Fee Rate
                           ---------------------------                          -------------------

                                                                                       
                           Greater than 1.80 to 1.00                                    0.20%

                           Less than or equal to 1.80 to 1.00
                             but greater than 1.50 to 1.00                              0.225%

                           Less than or equal to 1.50 to 1.00                           0.35%


                  The Applicable Commitment Fee Rate shall be adjusted effective
                  on the fifth Business Day after the delivery of Borrower's
                  quarterly or annual financial statements pursuant to SECTION
                  6.1(a) or 6.1(b), as applicable, provided that if timely
                  delivery of such quarterly or annual financial statements is
                  not made, for purposes of determining the Applicable
                  Commitment Fee Rate, the Fixed Charge 

   2



                  Coverage Ratio shall be assumed to be less than 1.50 to 1.00
                  until such delivery is made.

                  (b) Section 1.1 of the Credit Agreement is hereby amended by
         deleting therefrom the definition of "APPLICABLE LETTER OF CREDIT FEE
         RATE" and substituting therefor the following:

                           "APPLICABLE LETTER OF CREDIT FEE RATE" means, for any
                  date, with respect to Letters of Credit issued pursuant to or
                  governed by the terms of this Agreement, the applicable rate
                  per annum set forth below based on the Fixed Charge Coverage
                  Ratio as of the last day of the Borrower's most recently ended
                  fiscal quarter for the four consecutive fiscal quarters ending
                  with such fiscal quarter:



                                                                                 Applicable Letter of
                           Fixed Charge Coverage Ratio                               Credit Fee Rate
                           ---------------------------                               ---------------

                                                                                       
                           Greater than 1.80 to 1.00                                    0.90%

                           Less than or equal to 1.80 to 1.00
                           but greater than 1.50 to 1.00                                1.00%

                           Less than or equal to 1.50 to 1.00                           1.25%


                  The Applicable Letter of Credit Fee Rate shall be adjusted
                  effective on the fifth Business Day after the delivery of
                  Borrower's quarterly or annual financial statements pursuant
                  to SECTION 6.1(a) or 6.1(b), as applicable, provided that if
                  timely delivery of such quarterly or annual financial
                  statements is not made, for purposes of determining the
                  Applicable Margin, the Fixed Charge Coverage Ratio shall be
                  assumed to be less than 1.50 to 1.00 until such delivery is
                  made.

                  (c) Section 1.1 of the Credit Agreement is hereby amended by
         deleting therefrom the definition of "APPLICABLE MARGIN" and
         substituting therefor the following:

                           "APPLICABLE MARGIN" means, for any date, with respect
                  to the Loans comprising any Eurodollar Advance, the applicable
                  rate per annum set forth below for such Loans based on the
                  Fixed Charge Coverage Ratio as of the last day of the
                  Borrower's most recently ended fiscal quarter for the four
                  consecutive fiscal quarters ending with such fiscal quarter:



                           Fixed Charge Coverage Ratio                          Applicable Margin
                           ---------------------------                          -----------------

                                                                                       
                           Greater than 1.80 to 1.00                                    0.90%

                           Less than or equal to 1.80 to 1.00
                           but greater than 1.50 to 1.00                                1.00%

                           Less than or equal to 1.50 to 1.00                           1.25%


                  The Applicable Margin shall be adjusted effective on the fifth
                  Business Day after the delivery of Borrower's quarterly or
                  annual financial statements pursuant to SECTION 6.1(a) or
                  6.1(b), as applicable, provided that if timely delivery of
                  such quarterly or annual financial statements is not made, for
                  purposes of determining the Applicable Margin, the Fixed
                  Charge Coverage Ratio shall be assumed to be less than 1.50 to
                  1.00 until such delivery is made.

                  (d) Section 1.1 of the Credit Agreement is hereby amended to
         delete therefrom the definition of "CONVERTIBLE NOTES" and to
         substitute therefor the following:



                                      -2-
   3


                           "CONVERTIBLE NOTES" means the 5 3/4% Convertible
                  Subordinated Notes due 2003 and the 5% Convertible
                  Subordinated Notes due 2007 issued by the Borrower pursuant to
                  the terms of the respective Indentures.

                  (e) Section 1.1 of the Credit Agreement is hereby amended to
         delete therefrom the definition of "GAAP" and to substitute therefor
         the following:

                           "GAAP" means generally accepted accounting principles
                  as in effect from time to time.

                  (f) Section 1.1 of the Credit Agreement is amended hereby to
         delete therefrom the definition of "INDENTURE" and to substitute
         therefor the following:


                           "INDENTURES" means the Indenture dated as of October
                  1, 1993 by and between the Borrower and NBD Bank (formerly
                  known as NBD Bank, N.A.) and the Indenture dated as of
                  December 10, 1997 by and between the Borrower and The First
                  National Bank of Chicago, in each case as the same may be
                  amended or modified from time to time, pursuant to which the
                  respective Convertible Notes were issued.

                  (g) Section 1.1 of the Credit Agreement is hereby amended to
         delete therefrom the definition of "PERMITTED ACQUISITION" and to
         substitute therefor the following:

                           "PERMITTED ACQUISITION" means any Acquisition made by
                  the Borrower or any of its Subsidiaries provided that: (a) as
                  of the date of such Acquisition, no Default or Unmatured
                  Default shall have occurred and be continuing or would result
                  from such Acquisition or from the incurrence of any
                  Indebtedness in connection with such Acquisition; (b) prior to
                  the date of such Acquisition, such Acquisition shall have been
                  approved by the board of directors and, if applicable, the
                  shareholders of the Person whose stock or assets are being
                  acquired in connection with such Acquisition and no claim or
                  challenge has been asserted or threatened by any shareholder
                  or director of such Person which could reasonably be expected
                  to have a material adverse effect on such Acquisition or a
                  Material Adverse Effect; (c) as of the date of any such
                  Acquisition, all approvals required in connection with such
                  Acquisition shall have been obtained; and (d) any such
                  Acquisition is an Acquisition of the assets or capital stock
                  or other equity interests of a Person engaged in any line of
                  business being conducted by the Borrower or any of its
                  Subsidiaries at the time of such Acquisition or of a Health
                  Care Company.

                  (h) SECTION 1.1 of the Credit Agreement is hereby amended by
         adding, alphabetically therein, the following new defined terms:

                           "HEALTH CARE COMPANY" means a Person that is engaged,
                  directly or indirectly, in (a) owning, operating or managing
                  one or more facilities which dispenses, markets or provides
                  healthcare products or services, including, without
                  limitation, pharmaceutical products or services, (b)
                  purchasing, repackaging, selling or dispensing pharmaceutical
                  products, (c) providing healthcare consulting and billing
                  services, (d) distributing medical supplies and equipment, (e)
                  providing infusion therapy products or services, (f) providing
                  respiratory services, equipment or supplies, (g) providing
                  parenteral and enteral nutrition products, wound care
                  products, osotomy and urological supplies, (h) providing home
                  health care services, (i) providing dialysis services, (j)
                  providing contract pharmaceutical research services, (k)
                  providing disease and outcome management services, including
                  formulary services, (l) providing orthopedic supplies and
                  services, (m) providing information technology, including
                  software products and services, to Persons engaged in any of
                  the foregoing businesses, including long term care
                  institutions, (n) providing any service or product described
                  in the Standard 


                                      -3-
   4



                  Industrial Classification Manual (1987 Revision) published by
                  the Office of Management and Budget under the heading Industry
                  No. 5047, 5122, 5912 or 8731 or Major Group 80 as a whole, (o)
                  providing any product or service ancillary or incidental to
                  the healthcare industry to any customer or client of any of
                  the foregoing Persons, or (p) providing any other healthcare
                  related products or services.

                           "UTILIZATION FEE RATE" means the applicable per
                  annum rate set forth below based upon the Fixed Charge
                  Coverage Ratio as of the last day of the Borrower's most
                  recently ended fiscal quarter for the four consecutive fiscal
                  quarters ending with such fiscal quarter:



                           Fixed Charge Coverage Ratio                          Utilization Fee Rate
                           ---------------------------                          --------------------

                                                                                       
                           Greater than 1.80 to 1.00                                    0.10%

                           Less than or equal to 1.80 to 1.00
                             but greater than 1.50 to 1.00                              0.15%

                           Less than or equal to 1.50 to 1.00                           0.25%


                  The Utilization Fee Rate shall be adjusted effective on the
                  fifth Business Day after the delivery of Borrower's quarterly
                  or annual financial statements pursuant to SECTION 6.1(a) or
                  6.1(b), as applicable, provided that if timely delivery of
                  such quarterly or annual financial statements is not made, for
                  purposes of determining the Utilization Fee Rate, the Fixed
                  Charge Coverage Ratio shall be assumed to be less than 1.50 to
                  1.00 until such delivery is made.

                           "YEAR 2000 ISSUES" means, with respect to any
                  computer-related systems of the Borrower and its Subsidiaries,
                  anticipated costs, problems and uncertainties associated with
                  the inability of certain computer applications to effectively
                  handle data including dates on and after January 1, 2000, as
                  such inability affects the business, operations, and financial
                  condition of the Borrower and its Subsidiaries.

                           "364-DAY FACILITY" means a senior unsecured revolving
                  credit facility in an amount not to exceed $400,000,000 in
                  principal Indebtedness and having a maturity of 364 days,
                  subject to the Borrower's option to convert the revolving
                  loans outstanding thereunder to a one-year term loan, to be
                  entered into between the Borrower, certain lenders and First
                  Chicago, as agent for such lenders, as such facility may be
                  amended, restated or otherwise modified from time to time, and
                  any similar facility which refinances or replaces such
                  facility, but subject in any event to the foregoing limitation
                  in principal amount.

                  (i) Section 2.11 of the Credit Agreement is hereby amended as
follows:

                           (i) The phrase "COMMITMENT FEE; REDUCTIONS IN
                           AGGREGATE COMMITMENT" is hereby deleted and replaced
                           with the following: "COMMITMENT AND UTILIZATION FEES;
                           REDUCTIONS IN AGGREGATE COMMITMENT."

                           (ii) The character "(i)" is hereby inserted after the
                           character "(a)".

                           (iii) The following sentence is hereby inserted at
                           the end of SECTION 2.11(a):

                                    "(ii) The Borrower agrees that if, at the
                                    end of any fiscal quarter, commencing with
                                    the fiscal quarter ending December 31, 1998,
                                    the average daily aggregate principal amount
                                    of outstanding Loans during such quarter
                                    exceeded fifty percent (50%) of the average
                                    daily amount of the Aggregate Commitment
                                    during such quarter, the Borrower shall pay
                                    to the Agent, for the ratable account of
                                    each 



                                      -4-
   5


                                    Lender, a utilization fee at the Utilization
                                    Fee Rate on the average daily aggregate
                                    principal amount of all outstanding Loans
                                    during such quarter, payable not later than
                                    five (5) Business Days following the last
                                    day of such quarter. The period from and
                                    including the first day of the fiscal
                                    quarter in which the "Termination Date" (as
                                    defined below) occurs to but excluding the
                                    date which is the earliest of the Facility
                                    Termination Date, the date of the reduction
                                    to zero of the Aggregate Commitment pursuant
                                    to SECTION 2.11 and the date of the
                                    termination of the Aggregate Commitment
                                    pursuant to SECTION 8.1 (the "TERMINATION
                                    DATE") shall be treated as if it were a
                                    fiscal quarter (but having only the actual
                                    number of days of such period) for purposes
                                    of the foregoing fee calculation, and the
                                    utilization fee, if any, for such period
                                    shall be payable on such Termination Date.

                  (j) ARTICLE V of the Credit Agreement is amended to insert the
      following new SECTION 5.17 at the end thereof:

                           5.17. YEAR 2000. The Borrower and its Subsidiaries
                  have made an assessment of the Year 2000 Issues and in good
                  faith believe they have a realistic and achievable program for
                  remediating the Year 2000 Issues on a timely basis and a
                  reasonable contingency plan to address any inability of
                  computer applications in the computer systems of their
                  material customers, suppliers and vendors to effectively
                  handle data including dates on and after January 1, 2000.
                  Based on such assessment and program, the Borrower and its
                  Subsidiaries do not reasonably anticipate that Year 2000
                  Issues will have a Material Adverse Effect.

                  (k) SECTION 6.12 of the Credit Agreement is amended by adding
      the following proviso at the end thereof:

                  ; PROVIDED, HOWEVER, that nothing contained in this SECTION
                  6.12 shall prohibit any payment or prepayment of Indebtedness
                  under the 364-Day Facility.

                  (l) SECTION 6.14 of the Credit Agreement is amended (i) by
      amending CLAUSE (a) thereof in its entirety to read as follows: "(a)
      Investments described on SCHEDULE 1 hereto;"; (ii) by adding at the end of
      CLAUSE (b) thereof the following proviso: "PROVIDED that if such
      Investment is an Acquisition, it shall be a Permitted Acquisition;"; and
      (iii) by deleting the reference to "SECTION 6.15(e)" in CLAUSE (m) thereof
      and substituting therefor a reference to "SECTION 6.15(g)".

                  (m) SECTION 6.15 of the Credit Agreement is amended in its
      entirety to read as follows by adding the following proviso at the end
      thereof:

                           6.15. CONTINGENT OBLIGATIONS. The Borrower will not,
                  nor will it permit any of its Subsidiaries to, make or suffer
                  to exist any Contingent Obligation, except (a) by endorsement
                  of instruments for deposit or collection in the ordinary
                  course of business, (b) pursuant to the Guaranties, (c)
                  Contingent Obligations of the Borrower and any of its
                  Subsidiaries described on SCHEDULE 1 hereto, (d) Contingent
                  Obligations incurred by the Borrower in respect of the
                  obligations (other than obligations constituting Indebtedness
                  of the types described in CLAUSES (a), (d), (e) and, to the
                  extent issued in support of Indebtedness of the types
                  described in such CLAUSES (a), (d) and (e), CLAUSE (h) of the
                  definition of "Indebtedness") of any Guarantor, (e) Contingent
                  Obligations incurred by any Guarantor in respect of
                  obligations (other than obligations constituting Indebtedness
                  of the types described in CLAUSES (a), (d), (e) and, to the
                  extent issued in support of Indebtedness of the types
                  described in such CLAUSES (a), (d) and (e), CLAUSE (h) of the
                  definition of "Indebtedness") of any of its Subsidiaries that
                  is a Guarantor, (f) Contingent Obligations incurred by any
                  Subsidiary in respect of the obligations of any of its
                  Subsidiaries and existing at the time such Subsidiary is
                  acquired, directly or indirectly, by the Borrower and not
                  incurred in anticipation of such Acquisition, and Contingent
                  Obligations incurred by the Borrower in respect 



                                      -5-
   6


                  of any such obligations, and (g) other Contingent Obligations,
                  together with Investments permitted pursuant to SECTION
                  6.14(m), not to exceed in the aggregate more than 5% of
                  Consolidated Net Worth; PROVIDED, HOWEVER, that nothing
                  contained in this SECTION 6.15 shall prohibit any Subsidiary
                  of the Borrower that is a Guarantor from also guaranteeing the
                  repayment of Indebtedness under the 364- Day Facility.

                  (n) ARTICLE VI of the Credit Agreement is amended to insert
      the following new Section 6.21 at the end thereof:

                           6.21. YEAR 2000. The Borrower shall take and will
                  ensure its Subsidiaries take all actions reasonably necessary
                  to assure that the Year 2000 Issues will not have a Material
                  Adverse Effect and to implement their contingency plan to
                  address any inability of computer applications in the computer
                  systems of their material customers, suppliers and vendors to
                  effectively handle data including dates on and after January
                  1, 2000. The Borrower, on behalf of itself and its
                  Subsidiaries, will promptly notify the Agent in writing of any
                  reasonably anticipated Material Adverse Effect as a result of
                  Year 2000 Issues or as a result of any such inability with
                  respect to their material customers, suppliers and vendors.

                  (o) SECTION 9.6 of the Credit Agreement is amended by deleting
      the parenthetical phrase "(and their directors, officers and employees
      with respect to SECTION 9.7)" in the last sentence thereof and
      substituting therefor the parenthetical phrase "(and their Affiliates and
      respective directors, officers and employees with respect to SECTION
      9.7)".

                  (p) SECTION 9.7 of the Credit Agreement is amended by amending
      the third sentence thereof in its entirety to read as follows:

                  The Borrower further agrees to indemnify the Agent, each
                  Lender and their respective Affiliates, and such entities'
                  respective directors, officers and employees (each an
                  "Indemnitee") against all losses, claims, damages, penalties,
                  judgments, liabilities and expenses (including, without
                  limitation, all reasonable expenses of litigation or
                  preparation therefor whether or not the Agent or any Lender is
                  a party thereto) which any of them may pay or incur arising
                  out of or relating to this Agreement, the other Loan
                  Documents, the transactions contemplated hereby or the direct
                  or indirect application or proposed application of the
                  proceeds of any Loan or Letter of Credit hereunder except to
                  the extent that such losses, claims, damages, penalties,
                  judgments, liabilities and expenses are found in a final
                  judgment by a court of competent jurisdiction to have arisen
                  solely from the Gross Negligence or willful misconduct of such
                  Indemnitee.

                  (q) SECTION 12.2.1 of the Credit Agreement is amended by
      amending the proviso at the end of the first sentence threof in its
      entirety to read as follows:

                  PROVIDED, HOWEVER, that if a Participant is an Affiliate of
                  such Lender or if a Default has occurred and is continuing,
                  the consent of the Borrower shall not be required.

                  (r) SCHEDULE 1 of the Credit Agreement is amended by deleting
      the portions thereof identified as SCHEDULE 1B.2-OTHER INVESTMENTS and
      SCHEDULE 1D-CONTINGENT OBLIGATIONS and substituting therefor the Schedules
      attached hereto as SCHEDULE IB.2-OTHER INVESTMENTS and SCHEDULE
      ID-CONTINGENT OBLIGATIONS, respectively.

         3. CONDITIONS OF EFFECTIVENESS. This Amendment shall become effective
and be deemed effective as of the date hereof (the "Effective Date") if, and
only if, the Agent shall have received each of the following:

                  (a) duly executed originals of this Amendment from the
         Borrower and the Required Lenders;



                                      -6-
   7


                  (b) the Reaffirmation attached hereto duly executed on behalf
         of each of the Initial Guarantors and Supplemental Guarantors; and

                  (c) evidence reasonably satisfactory to the Agent that the
         364-Day Facility has been successfully syndicated and that all
         conditions precedent to the effectiveness of the 364- Day Facility
         (other than the effectiveness of this Amendment) have been satisfied or
         waived;

      4. REFERENCE TO AND EFFECT ON THE CREDIT AGREEMENT.

         4.1 Upon the effectiveness of this Amendment pursuant to Section 3
hereof, on and after the Effective Date each reference in the Credit Agreement
to "this Agreement," "hereunder," "hereof," "herein" or words of like import and
each reference to the Credit Agreement in each Loan Document shall mean and be a
reference to the Credit Agreement as modified hereby.

         4.2 Except as specifically waived or amended herein, all of the terms,
conditions and covenants of the Credit Agreement and the other Loan Documents
shall remain in full force and effect and are hereby ratified and confirmed.

         4.3 The execution, delivery and effectiveness of this Amendment shall
not, except as expressly provided herein, operate as a waiver of (a) any right,
power or remedy of any Lender or the Agent under the Credit Agreement or any of
the Loan Documents, or (b) any Default or Unmatured Default under the Credit
Agreement.

         5. CHOICE OF LAW. THIS AMENDMENT SHALL BE CONSTRUED IN ACCORDANCE WITH
THE INTERNAL LAWS (INCLUDING 735 ILCS 105/5-1 ET SEQ. BUT OTHERWISE WITHOUT
REGARD TO THE CONFLICT OF LAWS PROVISIONS) OF THE STATE OF ILLINOIS, BUT GIVING
EFFECT TO FEDERAL LAWS APPLICABLE TO NATIONAL BANKS.

         6. COUNTERPARTS. This Amendment may be executed in any number of
counterparts, each of which when so executed shall be deemed an original and all
of which taken together shall constitute one and the same agreement.

         7. HEADINGS. Section headings in this Amendment are included herein for
convenience of reference only and shall not constitute a part of this Amendment
for any other purpose.



                                      -7-
   8


         IN WITNESS WHEREOF, the Borrower, the Agent and the Lenders have
executed this Amendment No. 2 as of the date first above written.


                                    OMNICARE, INC.


                                    By:        /s/ David W. Froesel, Jr.
                                        ----------------------------------------
                                        Name:  David W. Froesel, Jr.
                                        Title: Chief Financial Officer


                                    THE FIRST NATIONAL BANK OF CHICAGO,
                                      as a Lender and as Agent


                                    By:        /s/ Patricia S. Carpen
                                        ----------------------------------------
                                        Name:  Patricia S. Carpen
                                        Title: Vice President


                                    BANK OF TOKYO-MITSUBISHI, LTD., CHICAGO
                                    BRANCH, as a Lender


                                    By:        /s/ Hajime Watanabe
                                        ----------------------------------------
                                        Name:  Hajime Watanabe
                                        Title: Deputy General Manager


                                    COMERICA BANK, as a Lender


                                    By:        /s/ Lee J. Santioni
                                        ----------------------------------------
                                        Name:  Lee J. Santioni
                                        Title: First Vice President

                                    KEYBANK NATIONAL ASSOCIATION,
                                    as a Lender


                                    By:        /s/ Thomas J. Purcell
                                        ----------------------------------------
                                        Name:  Thomas J. Purcell
                                        Title: Vice President


                                    PNC BANK, OHIO, NATIONAL ASSOCIATION
                                    as a Lender


                                    By:        /s/ Anne B. Kelly
                                        ----------------------------------------
                                        Name:  Anne B. Kelly
                                        Title: Vice President


                                    THE BANK OF NEW YORK, as a Lender


                                    By:        /s/ Edward J. Dougherty III
                                        ----------------------------------------



                                      -8-
   9


                                        Name:  Edward J. Dougherty III
                                        Title: Vice President, U.S. Commercial 
                                               Lending


                                    BANQUE NATIONALE DE PARIS,
                                    as a Lender


                                    By:        /s/ Arnaud Collin de Bocage
                                        ----------------------------------------
                                        Name:  Arnaud Collin de Bocage
                                        Title: Executive Vice President and
                                               General Manager


                                    CIBC, INC., as a Lender


                                    By:        /s/ Gerald Girardi
                                        ----------------------------------------
                                        Name:  Gerald Girardi
                                        Title: Executive Director, CIBC
                                               Oppenheimer Corp., as Agent


                                    THE FIFTH THIRD BANK, as a Lender


                                    By:        /s/ Andrew K. Hauck
                                        ----------------------------------------
                                        Name:  Andrew K. Hauck
                                        Title: Vice President


                                    THE FUJI BANK, LIMITED, as a Lender


                                    By:        /s/ Tetsuo Kamatsu
                                        ----------------------------------------
                                        Name:  Tetsuo Kamatsu (K-219)
                                        Title: Joint General Manager


                                    SAKURA BANK, LIMITED, as a Lender


                                    By:        /s/ Masayuki Kobayashi
                                        ----------------------------------------
                                        Name:  Masayuki Kobayashi
                                        Title: Joint General Manager


                                    THE SANWA BANK, LIMITED, CHICAGO
                                    BRANCH, as a Lender


                                    By:           NOT REQUIRED
                                        ----------------------------------------
                                        Name:
                                        Title:


                                    STAR BANK, N.A., as a Lender


                                    By:        /s/ Derek S. Roudebush
                                        ----------------------------------------
                                        Name:  Derek S. Roudebush



                                      -9-
   10


                                        Title: Vice President


                                    THE DAI-ICHI KANGYO BANK, LTD.,
                                       CHICAGO BRANCH, as a Lender


                                    By:        /s/ Nobuyasu Fukatsu
                                        ----------------------------------------
                                        Name:  Nobuyasu Fukatsu
                                        Title: Vice President


                                    LONG TERM CREDIT BANK OF JAPAN, LTD.,
                                    as a Lender


                                    By:        /s/ Brady S. Sakek
                                        ----------------------------------------
                                        Name:  Brady S. Sakek
                                        Title: Senior Vice President


                                    BANCA CRT S.P.A., as a Lender


                                    By:        /s/ J. Slade Carter, Jr.
                                        ----------------------------------------
                                        Name:  J. Slade Carter, Jr.
                                        Title: Vice President


                                    By:        /s/ Robert P. DeSantes .
                                        ----------------------------------------
                                        Name:  Robert P. DeSantes.
                                        Title: First Vice President




                                      -10-

   11



                                  REAFFIRMATION



                  Each of the undersigned hereby acknowledges receipt of a copy
of the foregoing Amendment No. 2 to the Credit Agreement dated as of October 22,
1996 by and among Omnicare, Inc., a Delaware corporation (the "Borrower"), the
lenders from time to time parties thereto (collectively, the "Lenders") and The
First National Bank of Chicago, as one of the Lenders and in its capacity as
contractual representative (the "Agent") on behalf of itself and the other
Lenders, as amended by an Amendment No. 1 dated as of November 3, 1997 (as
amended and as the same may be amended, restated, supplemented or otherwise
modified from time to time, the "Credit Agreement") which Amendment No. 2 is
dated as of December 21, 1998 (the "Amendment"). Capitalized terms used in this
Reaffirmation and not defined herein shall have the meanings given to them in
the Credit Agreement. Without in any way establishing a course of dealing by the
Agent or any Lender, each of the undersigned reaffirms the terms and conditions
of the Guaranty executed by it and acknowledges and agrees that such agreement
and each and every other Loan Document executed by the undersigned in connection
with the Credit Agreement remain in full force and effect and are hereby
reaffirmed, ratified and confirmed. All references to the Credit Agreement
contained in the above-referenced documents shall be a reference to the Credit
Agreement as so modified by the Amendment and as the same may from time to time
hereafter be amended, modified or restated.



                                            AAHS ACQUISITION CORP.
                                            ACP ACQUISITION CORP.
                                            AMC-NEW YORK, INC.
                                            AMC REGIONAL HOLDINGS, INC.
                                            AMC TENNESSEE, INC.
                                            AMERICAN MEDSERVE CORPORATION
                                            ANDERSON MEDICAL SERVICES, INC.
                                            APEX LONG TERM CARE PHARMACY, INC.
                                            BEEBER PHARMACIES, INC.
                                            BPNY ACQUISITION CORP.
                                            BPTX ACQUISITION CORP.
                                            CARE PHARMACEUTICAL SERVICES, INC.
                                            CHP ACQUISITION CORP.
                                            CONSULTING AND PHARMACEUTICAL
                                               SERVICES, INC.
                                            COROMED, INC.
                                            CTLP ACQUISITION CORP.
                                            D&R PHARMACEUTICAL SERVICES, INC.
                                            DATASCRIPT CORP.
                                            DIXON PHARMACY, INC.
                                            DOWNEAST PHARMACY, INC.
                                            DYNATRAN COMPUTER SYSTEMS, INC.
                                            EHIS ACQUISITION CORP.
                                            ELECTRA ACQUISITION CORP.
                                            ENLOE DRUGS, INC.
                                            EVERGREEN PHARMACEUTICAL, INC.
                                            EVERGREEN PHARMACEUTICAL EAST,
                                               INC.
                                            EVERGREEN PHARMACEUTICAL SUPPLY,
                                               INC.
                                            EVERGREEN SPOKANE, INC.
                                            FREED'S PHARMACY, INC.
                                            GATTI LTC SERVICES, INC.
                                            HCC MEDICAL SUPPLY, INC.
                                            HMIS, INC.



Guaranty Reaffirmation


                                      -11-
   12






                                            HOME CARE PHARMACY, INC.
                                            HOME PHARMACY SERVICES, INC.
                                            HOSPICE CARE OF OKLAHOMA, L.L.C.
                                            HOSPICE OF THE HEARTLAND, L.L.C.
                                            HOWARD'S PHARMACY, INC.
                                            INTERLOCK PHARMACY SYSTEMS, INC.
                                            I.V. SERVICES OF OKLAHOMA, INC.
                                            KONSULT, INC.
                                            LANGSAM HEALTH SERVICES, INC.
                                            LANGSAM MEDICAL PRODUCTS, INC.
                                            LAWRENCE MEDICAL SUPPLY, INC.
                                            LO-MED PRESCRIPTION SERVICES, INC.
                                            MANAGED HEALTH CARE, INC.
                                            MED WORLD ACQUISITION CORP.
                                            MEDICAL ARTS HEALTH CARE, INC.
                                            MEDICAL COMMUNICATIONS SOFTWARE,
                                               INC.
                                            MOSI ACQUISITION CORP.
                                            NIHAN & MARTIN, INC.
                                            NORTH SHORE PHARMACY SERVICES, INC.
                                            OCR-RA ACQUISITION CORP.
                                            OCR SERVICES CORPORATION
                                            OKLAHOMA CONSULTING SERVICES, INC.
                                            OMNICARE MANAGEMENT COMPANY
                                            PBM-PLUS, INC.
                                            PHARMACY ASSOCIATES OF GLENS FALLS,
                                               INC.
                                            PHARMED HOLDINGS, INC.
                                            PIP ACQUISITION CORP.
                                            POMPTON NURSING HOME SUPPLIERS,
                                               INC.
                                            PRN PHARMACEUTICAL SERVICES, INC.
                                            PROFESSIONAL PHARMACY GROUP, INC.
                                            PW ACQUISITION CORP.
                                            RDSI ACQUISITION CORP.
                                            SC ACQUISITION CORP.
                                            SHORE PHARMACEUTICAL PROVIDERS,
                                               INC.
                                            SPECIALIZED PATIENT CARE SERVICES,
                                               INC.
                                            SPECIALIZED PHARMACY SERVICES, INC.
                                            STERLING HEALTHCARE SERVICES, INC.
                                            SUPERIOR CARE PHARMACY, INC.
                                            TCPI ACQUISITION CORP.
                                            THG ACQUISITION CORP.
                                            THREE FORKS APOTHECARY, INC.
                                            UC ACQUISITION CORP.
                                            UNITED HEALTH CARE, INC.
                                            UNITED HEALTH REFERRAL, INC.
                                            UNITED SKIN THERAPEUTICS, INC.
                                            VALUE PHARMACY, INC.
                                            WEBER MEDICAL SYSTEMS, INC.
                                            WESTHAVEN SERVICES CO.
                                            WEST-VAL CARE, INC.
                                            WILLIAMSON DRUG COMPANY,
                                               INCORPORATED
                                            WINSLOW'S PHARMACY(1)



- --------------
1  Company to confirm list of guarantors.


Guaranty Reaffirmation


                                      -12-
   13





                                 On behalf of each of the above-listed parties:

                                 By:
                                    ------------------------------------
                                    Name:
                                    Title:








Guaranty Reaffirmation


                                      -13-