SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549
                                 ---------------

                                    FORM 10-Q


   [X] QUARTERLY REPORT UNDER SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE
                                   ACT OF 1934

                  For the Quarterly Period Ended March 31, 1997

                                       OR

    [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES
                              EXCHANGE ACT OF 1934
                        For the transition period from to

                        Commission file number 000-19392


                              DIANON SYSTEMS, INC.
             (exact name of registrant as specified in its charter)


                   Delaware                               06-1128081
           (State of incorporation)            (IRS Employer Identification No.)

  
        200 Watson Blvd, Stratford, CT                       06497
   (Address of principal executive offices)               (zip code)


       Registrant's telephone number, including area code: (203) 381-4000


                                 NOT APPLICABLE
              (Former name, former address and former fiscal year,
                          if changed since last report)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed  by  Section  13 or 15 (d) of the  Securities  Exchange  Act of 1934
during the preceding 12 months (or for such shorter  period that the  registrant
was  required  to file such  reports) and (2) has  been  subject to such  filing
requirements for the past 90 days.

                                                            Yes  X        No
                                                                ---

The number of shares of Issuer's  Common Stock,  $.01 par value,  outstanding on
May 5, 1997 was 6,437,476 shares.

                    Exhibit Index is on page 15 of 16 pages.


                              DIANON SYSTEMS, INC.
                                AND SUBSIDIARIES

                                      INDEX




PART I FINANCIAL INFORMATION                                       PAGE NO.
- ----------------------------                                       --------
                                                               
Item 1.   FINANCIAL STATEMENTS

          Consolidated Balance Sheets as of  March 31, 1997          3
          and December 31, 1996

          Consolidated  Statements  of  Operations  for the          4
          three months ended March 31, 1997 and 1996

          Consolidated  Statements of Stockholders'  Equity          5
          for the twelve months ended December 31, 1996 and
          the three months ended March 31, 1997

          Consolidated  Statements  of Cash  Flows  for the          6
          three months ended March 31, 1997 and 1996

          Notes to Consolidated Financial Statements                 7


Item 2.   MANAGEMENT'S    DISCUSSION    AND   ANALYSIS   OF          8-12
          FINANCIAL CONDITION AND RESULTS OF OPERATIONS


PART II OTHER INFORMATION
- -------------------------

Item 6.   EXHIBITS AND REPORTS ON FORM 8-K                           13

Signatures                                                           14

Exhibit Index                                                        15




                              DIANON SYSTEMS, INC.
                           CONSOLIDATED BALANCE SHEETS


                                                   MARCH 31,      DECEMBER 31,
                                                     1997            1996
                                                --------------------------------
                                                 (UNAUDITED)
                                                            
  ASSETS
CURRENT ASSETS:
  Cash and cash equivalents                      $  9,566,608     $  7,488,590
  Accounts receivable, net of
     allowances of $1,027,705
     and $1,056,920, respectively                  13,366,168       15,426,221
  Prepaid expenses and employee advances            1,074,135        1,189,139
  Prepaid and refundable income taxes                      --          329,371
  Inventory                                           604,359          662,567
  Deferred income tax asset                           677,277          677,277
                                                --------------------------------
     Total current assets                          25,288,547       25,773,165
                                                --------------------------------
PROPERTY AND EQUIPMENT, at cost
  Laboratory and office equipment                  12,581,716       12,233,989
  Leasehold improvements                            3,634,207        3,612,198
     Less - accumulated depreciation
     and amortization                              (9,138,911)      (8,606,176)
                                                --------------------------------
                                                    7,077,012        7,240,011
                                                -------------------------------- 
INTANGIBLE ASSETS, net of accumulated
  amortization of $3,045,357 and
  $2,991,286, respectively                            550,242          604,313
DEFERRED INCOME TAX ASSET                             458,465          458,465
OTHER ASSETS                                          419,339          459,696
                                                --------------------------------
     TOTAL ASSETS                                $ 33,793,605     $ 34,535,650
                                                ================================
     LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES:
  Accounts payable                               $    976,840     $  1,903,448
  Accrued employee bonuses, 
  commissions and payroll                           1,167,750        1,504,430
  Accrued employee stock purchase plan                741,717          549,540
  Current portion of capitalized 
     lease obligations                                 26,696           26,107
  Current portion of note payable                     412,167          650,154
  Other accrued expenses                            4,651,804        3,081,481
                                                --------------------------------
     Total current liabilities                      7,976,974        7,715,160
                                                --------------------------------
LONG-TERM PORTION OF CAPITALIZED LEASE
     OBLIGATIONS                                       62,644           69,611
DEFERRED INCOME TAX LIABILITY                         201,951          201,951
                                                --------------------------------
     TOTAL LIABILITIES                              8,241,569        7,986,722
                                                --------------------------------
STOCKHOLDERS' EQUITY
  Common stock, par value $.01 per share,
     20,000,000 shares authorized,
     6,749,638 and 6,712,774 shares
     issued and outstanding at March 31,
     1997 and December 31, 1996, respectively          67,496           67,128
  Additional paid-in capital                       28,197,383       27,965,560
  Accumulated earnings/(deficit)                       63,880         (554,317)
  Common stock held in treasury, at cost -
     334,196 and 117,196 shares at March 31,
     1997 and December 31, 1996, respectively      (2,776,723)        (929,443)
                                                --------------------------------
     TOTAL STOCKHOLDERS' EQUITY                     25,552,036      26,548,928
                                                ================================
     TOTAL LIABILITIES AND STOCKHOLDERS'
        EQUITY                                    $ 33,793,605    $ 34,535,650
                                                ================================

                The accompanying notes to consolidated financial
            statements are an integral part of these balance sheets.


                              DIANON SYSTEMS, INC.
                      CONSOLIDATED STATEMENTS OF OPERATIONS
                           FOR THE THREE MONTHS ENDED
                             MARCH 31, 1997 AND 1996
                                   (UNAUDITED)



                                                         THREE MONTHS ENDED
                                                               MARCH 31,
                                                          1997          1996
                                                      -----------   -----------
                                                                      
NET REVENUES                                          $15,601,155   $12,418,819
                                       
COST OF SALES                                           7,872,499     6,138,888
                                                      -----------   -----------

    Gross Profit                                        7,728,656     6,279,931

SELLING, GENERAL AND
    ADMINISTRATIVE EXPENSES                             6,217,482     5,067,181

RESEARCH AND DEVELOPMENT
    EXPENSES                                              507,705       806,901
                                                      -----------   -----------

Income from Operations                                  1,003,469       405,849

INTEREST INCOME                                            91,890       124,545

INTEREST EXPENSE                                           10,803        24,201
                                                      -----------   -----------

Income Before Provision for Income Taxes                1,084,556       506,193

PROVISION FOR INCOME TAXES                                466,359       217,663
                                                      -----------   -----------

    Net Income                                        $   618,197   $   288,530
                                                      ===========   ===========

Weighted Average Shares Outstanding                     6,835,289     6,248,926
                                                      -----------   -----------

Primary and Fully Diluted Earnings Per Share          $       .09   $       .05
                                                      ===========   ===========


                The accompanying notes to consolidated financial
              statements are an integral part of these statements.



                              DIANON SYSTEMS, INC.
                 CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
                FOR THE TWELVE MONTHS ENDED DECEMBER 31, 1996 AND
                      THE THREE MONTHS ENDED MARCH 31, 1997
                                   (UNAUDITED)


                                                                                    Common Stock
                                                        Additional                  Acquired for   Shareholder
                                      Common Stock        Paid-In     Accumulated   Treasury,      Note 
                                    Shares     Amount     Capital       Deficit     at Cost        Receivable        Total
                                  -------------------   -----------   ------------  ------------   -----------    -----------
                                                                                             
BALANCE, December 31, 1995        6,311,451   $63,115   $26,609,657   ($2,724,433)    ($200,000)    ($296,000)    $23,452,339
 Stock options exercised             23,621       236       107,476            --            --            --         107,712
 Exercise of warrants
  net of exercise costs             377,702     3,777     1,536,540            --     2,478,889            --       4,019,206
 Common stock acquired
  for treasury                           --        --            --            --    (3,208,332)           --      (3,208,332)
 Extinguishment of share-
  holder note receivable                 --        --      (296,000)           --            --       296,000              --
 Stock compensation 
  expense - stock options                --        --         7,887            --            --            --           7,887
 Net Income                              --        --            --     2,170,116            --            --       2,170,116
                                  ---------   -------   -----------   -----------   -----------     ---------     -----------

BALANCE, December 31, 1996        6,712,774    67,128    27,965,560      (554,317)     (929,443)           --      26,548,928
 Stock options exercised             20,724       207        94,294            --            --            --          94,501
 Stock grants                        16,140       161       137,529            --            --            --         137,690
 Common stock acquired for
  treasury                               --        --            --            --    (1,847,280)           --      (1,847,280)
 Net Income                              --        --            --       618,197            --            --         618,197
                                  ---------   -------   -----------   -----------   -----------     ---------     -----------
BALANCE, March 31, 1997           6,749,638   $67,496   $28,197,383    $   63,880   ($2,776,723)     $     --     $25,552,036
                                  =========   =======   ===========   ===========   ===========     =========     ===========



                The accompanying notes to consolidated financial
              statements are an integral part of these statements.




                              DIANON SYSTEMS, INC.
                      CONSOLIDATED STATEMENTS OF CASH FLOWS
               FOR THE THREE MONTHS ENDED MARCH 31, 1997 AND 1996
                                   (UNAUDITED)



                                                               MARCH 31,
                                                          1997          1996
CASH FLOWS FROM OPERATING ACTIVITIES:                 -----------   ------------
                                                                      
    Net income                                        $   618,197   $   288,530
Adjustments to reconcile net income to net
    cash provided by (used in) operations -
    Non-cash charges
       Depreciation and amortization                      657,927       497,088
       Loss on the disposal of fixed assets                28,378        18,845
       Investment write-down                                   --         4,053
Changes in other current assets
    and liabilities
    Decrease (increase) in accounts receivable          2,060,053    (1,328,664)
    Decrease in prepaid expenses
       and employee advances                              444,375       433,819
    Decrease (increase) in inventory                       58,208       (41,064)
    Decrease (increase) in other assets                    28,417        (4,443)
    Increase (decrease) in accounts payable
       and accrued liabilities                            499,213      (551,319)
                                                      -----------   ------------
          Net cash provided by (used in)
          operating activities                          4,394,768      (683,155)
                                                      -----------   ------------

CASH FLOWS FROM INVESTING ACTIVITIES:                    
    Capital expenditures                                 (131,396)     (541,080)
    Construction in Progress                             (325,900)           --
    Proceeds from the sale of stock held for
       investment                                              --        57,530
    Proceeds from the disposal of fixed assets                 --         7,500
                                                      -----------   ------------
    Net cash (used in) investing activities              (457,296)     (476,050)
                                                      -----------   ------------

CASH FLOWS FROM FINANCING ACTIVITIES:
    Repayments of note payable                           (237,987)     (223,939)
    Repayments of capitalized lease obligations            (6,378)      (15,171)
    Purchase of common stock acquired for treasury     (1,847,280)      (67,500)
    Stock grants and stock options exercised              232,191            --
                                                      -----------   ------------
          Net cash (used in) financing activities      (1,859,454)     (306,610)
                                                      -----------   ------------
          Net increase (decrease) in cash and
              cash equivalents                          2,078,018    (1,465,815)

CASH AND CASH EQUIVALENTS, beginning of period          7,488,590    10,990,231
                                                      -----------   ------------
CASH AND CASH EQUIVALENTS, end of period              $ 9,566,608   $ 9,524,416
                                                      ===========   ============
Supplemental cash flow disclosures:
    Cash paid during the period:
       Interest                                       $    10,867        24,272
       Income Taxes                                           200           458


                The accompanying notes to consolidated financial
              statements are an integral part of these statements.



                              DIANON SYSTEMS, INC.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1.    THE COMPANY - The  consolidated  balance  sheet as of March 31, 1997,  the
      related consolidated  statements of operations and consolidated  statement
      of cash flows for the three months ended March 31, 1997 and 1996,  and the
      related  consolidated  statements of  stockholders'  equity for the twelve
      months  ended  December 31, 1996 and the three months ended March 31, 1997
      have been prepared by DIANON Systems,  Inc. (the "Company") without audit.
      In the opinion of management,  all adjustments necessary to present fairly
      the financial position,  results of operations and cash flows at March 31,
      1997 and 1996 have been made.  During the interim periods reported on, the
      accounting  policies  followed are in conformity  with generally  accepted
      accounting  principles  and are  consistent  with those applied for annual
      periods and  described in the  Company's  annual report filed on Form 10-K
      with the Securities and Exchange Commission on March 31, 1997 (the "Annual
      Report").

      Certain  information  and  footnote   disclosures   normally  included  in
      financial  statements  prepared  in  accordance  with  generally  accepted
      accounting  principles  have been  omitted.  It is  suggested  that  these
      consolidated   financial  statements  be  read  in  conjunction  with  the
      financial  statements included in the Company's Annual Report for the year
      ended  December 31, 1996.  The results of operations  for the three months
      ending  March  31,  1997 and 1996 are not  necessarily  indicative  of the
      operating results for the full years.

2.    DESCRIPTIVE ANALYSIS - The descriptive analysis  contained herein compares
      the  financial  results of the first three  months  ended March 31 for the
      years 1997 and 1996. To accommodate the comparison of pertinent  financial
      information  the  following  terms will be used to denote  the  respective
      periods:

     The First Quarter 1997 - current three months ended March 31, 1997
     The First Quarter 1996 - three months ended March 31, 1996



                MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
                       CONDITION AND RESULTS OF OPERATIONS
                   THREE MONTHS ENDED MARCH 31, 1997 AND 1996
                                   (UNAUDITED)


RESULTS OF OPERATIONS
- ---------------------

      O    NET REVENUES

Net revenues  were $15.6  million  during the First Quarter 1997, an increase of
$3.2  million  or 26% from the  First  Quarter  1996.  Increased  revenues  were
attributable to increased market penetration by the Company's anatomic pathology
testing  services.  The increase in anatomic  pathology  testing services in the
First Quarter 1997 over the comparable  period of 1996 was offset to some extent
by a decrease in clinical chemistry and hospital based tissue testing services.

      O    COST OF SALES

Cost of sales,  which  consists  primarily  of  salaries  and wages,  laboratory
supplies,  outside services,  logistics  (primarily shipping and handling),  and
depreciation  expense,  was $7.9  million  during  the First  Quarter  1997,  an
increase of $1.7 million or 28% from the First Quarter 1996.  Salaries and wages
were  approximately  $2.6  million in the First  Quarter  1997,  an  increase of
$604,000 or 31% from the First Quarter 1996.  This increase was  principally due
to  increased  laboratory  and  physician  employment  incurred  to support  new
anatomic pathology testing services. Laboratory supplies were approximately $1.5
million in the First Quarter 1997, an increase of $197,000 or 15% from the First
Quarter  1996.  This  increase  was the  result of  increased  sales  volume and
increased  costs for reagents used for some of the Company's  testing  services.
Logistics  were $1.7 million in the First  Quarter 1997, an increase of $789,000
or 84% from  the  First  Quarter  1996.  The  increase  in  logistic  costs  was
principally  due to supporting new anatomic  pathology  testing  services.  As a
percentage  of net  revenues,  cost of sales  increased  to 50% during the First
Quarter 1997 from 49% during the First Quarter 1996.

      O    GROSS PROFIT

Gross  profits were $7.7 million  during the First  Quarter 1997, an increase of
$1.4 million or 23% from the First  Quarter  1996.  The  Company's  gross profit
margin  decreased to 50% in the First Quarter 1997 from 51% in the First Quarter
1996.  The decrease in gross profit margin was due to the  continued  erosion of
the  average  unit price  reimbursed  for  certain  clinical  chemistry  testing
services and the higher  costs  associated  with  providing  anatomic  pathology
testing services.

The clinical  laboratory  industry,  which includes both clinical  chemistry and
anatomic pathology,  has seen steady downward pressure on prices exerted by both
government  and private third party payors.  Also,  payment for services such as
those  provided  by the  Company is and likely  will  continue to be affected by
periodic reevaluations made by payors concerning which services to reimburse and
which to cease reimbursing.  The reduction in reimbursement rates,  particularly
by  Medicare,  has  generally  decreased  the average unit price for most of the
Company's  clinical chemistry services each year. In keeping with this trend, as
part of Omnibus Budget Reconciliation Act of 1993 ("OBRA `93"), Congress reduced
over time the national cap on Medicare  laboratory fee schedules.  This national
cap has been lowered each year and now is 76% of the national  median.  OBRA `93
also eliminated the annual updates of Medicare  laboratory fee schedules for the
years 1994 and 1995. In 1996, however,  the fee schedule update was 3.2% and the
Health Care Financing  Administration  ("HCFA") has recently  announced that the
fee schedule update for 1997 will be 2.7%. However,  the corresponding  expected
national cap increase of 2.7% may not be fully  realized due to a  recalculation
of national medians necessitated by conversion in some carrier areas to a single
statewide fee schedule.

With respect to the Company's  tissue testing  services which are not reimbursed
under  the  Medicare  laboratory  fee  schedules,  the  Medicare  fees for these
services also generally  declined with the  implementation of the resource based
relative  value scale  ("RBRVS")  system  which went into effect in 1992 and was
fully phased in by the end of 1996.  The Medicare RBRVS payment for each service
is  calculated  by  multiplying   the  total  relative  value  units   ("RVU's")
established  for the  service by a  conversion  factor  that is set by law.  The



number of RVU's  assigned to each service is in turn  calculated by adding three
separate  components,  including one representing  the relative work values.  In
1996,  HCFA completed a five-year  review of the work value  component and, as a
result,  revised the work value amount assigned to many physician  services.  In
addition,  based on a default  formula  established in law, the 1997  conversion
factor  for  nonsurgical  services  dropped  0.8%  from  1996  to  $33.8454  per
conversion  factor.  The changes resulting from the five-year  review,  combined
with the  conversion  factor  reductions,  resulted  in an overall  decrease  in
payments for pathology services of approximately 5.7% beginning January 1, 1997.
Also, HCFA reduced the number of physician fee schedule payment  localities from
210 to 89,  effective  January 1, 1997.  Connecticut  was one of the states that
HCFA  moved to a single  payment  locality.  This  modification  created  a 3.2%
decrease in the RBRVS  geographic  adjustment  factor for physicians  located in
Western Connecticut,  where the Company's primary operations are located. In the
past, implementation of the RBRVS program has had the effect of reducing prices,
and  thus the  gross  profit,  of the  Company.  The  recent  substantial  RBRVS
adjustments are likely to continue this trend.

Furthermore, as a result of the Social Security Act amendments of 1994, Medicare
is required to revise the formula for calculating the practice expense component
of the physicians'  Medicare fee schedule from the current historical basis to a
resource  basis  beginning  January 1, 1998.  Some concern has been expressed by
physician  specialty  groups that the data HCFA plans to use for these revisions
is not adequate and that HCFA's  methodology could result in specialty  practice
expenses being  underestimated.  At this point, HCFA is considering a variety of
options for calculating practice expense revisions.  It is possible that certain
changes  HCFA  might  make  would  have  a   significant   negative   affect  on
reimbursement,  and thus gross profit,  for anatomic pathology testing services.
Practice  expenses  currently  account for  approximately 42% of the physicians'
Medicare fee schedule payment amount.

Any future changes in government and other third-party payor reimbursement which
may come about as a  consequence  of an  enactment  of health  care reform or of
deficit reduction legislation also likely will continue the downward pressure on
prices and make the market for clinical laboratory services more competitive.

The  Medicare  proposal  contained  in the  President's  fiscal year 1998 budget
offers an indication of the direction  future  Medicare  reform  legislation may
take with respect to clinical  laboratory  services.  The  President's  proposed
budget  would  not  modify  the  national  cap on  Medicare  clinical  chemistry
laboratory  fee  schedules  or  eliminate  annual  updates;  however,  it  would
establish competitive bidding for clinical chemistry laboratory services. If the
President's  proposal failed to realize savings of at least 20% for a given year
through the  competitive  bidding  process,  the Secretary of the  Department of
Health and Human Services  ("HHS") would reduce  Medicare's  fees for laboratory
services to achieve this targeted savings.  Furthermore, the President's support
for competitive bidding has rekindled efforts within HCFA to initiate a Medicare
demonstration  project to test the savings potential of competitive  bidding for
Part B clinical chemistry  laboratory  services.  If ultimately adopted,  either
through federal  legislation or through HCFA policy,  these changes likely would
have an adverse impact on the Company's revenues, and thus its gross profit.

Moreover,  the Congress has voiced concern that the President's  budget does not
yield  sufficient  savings  to  balance  the  budget in 2002.  As a result,  the
Congress is likely to propose  additional  savings  measures,  especially in the
Medicare program. H.R. 2491, the Balanced Budget Act of 1995, passed by Congress
and vetoed by President  Clinton in December  1995,  offers some  indication  of
additional  savings  measures that Congress may propose in the future.  Although
H.R. 2491 would not have established  competitive bidding for clinical chemistry
laboratory  services,  it instead  proposed that a failsafe budget  mechanism be
used if projected  savings were not realized in Medicare  service  expenditures.
This failsafe  mechanism might have further reduced  reimbursement  for Medicare
clinical chemistry  laboratory  services and physician  services  (including the
Company's anatomic pathology testing service). In addition, H.R. 2491 would have
further reduced the national cap on Medicare clinical  chemistry  laboratory fee
schedules to 65% of the national  median in 1997. It also would have  eliminated
annual updates in the Medicare clinical chemistry laboratory fee schedules until
fiscal year 2002.

Both the Medicare proposal  contained in the President's fiscal year 1998 budget
and H.R.  2491  would  revise  the  Medicare  program  substantially  to  permit
beneficiaries to choose between traditional fee-for-service Medicare and several
non-traditional   Medicare   options,   including   managed   care   plans   and
provider-sponsored  organization  plans.  These  non-traditional  Medicare plans
would have considerable  discretion in determining  whether and how to cover and



reimburse  clinical  laboratory  services  and to limit the  number of labs with
which they deal. Although neither proposal would require Medicare  beneficiaries
to pay 20% of the fee for  each  clinical  laboratory  service,  nothing  in the
proposals would prohibit non-traditional Medicare plans from implementing such a
requirement.

Both proposals  also would  implement a single  conversion  factor for physician
services. In 1998, this single conversion factor would likely be slightly higher
than the current conversion factor for pathologists.  If enacted,  this increase
may favorably  affect or, more likely,  offset to some degree the adverse impact
of the  other  developments  described  above on  revenues  from  the  Company's
anatomic pathology testing services.

Finally,  the Medicare  proposal  contained in the President's  fiscal year 1998
budget contains measures to establish  market-oriented  purchasing for Medicare,
including  prospective payment systems for out-patient  hospital services,  home
health care, and nursing home care, and the use of global  payments and flexible
purchasing.  Although the details of these proposals are yet to be developed, if
implemented,  they probably would  increase  pressure on pricing in the clinical
laboratory industry and may have an adverse impact on the Company's revenues.

Medicare changes along the lines just described are possible this year.  Because
of the uncertainties  about the exact nature of any changes which may ultimately
be adopted,  the Company currently is unable to predict their ultimate impact on
the clinical laboratory industry generally or on the Company in particular. Even
apart from federal legislative action,  reforms may occur at the state level and
changes  are  occurring  in the  marketplace  as a result of  market  pressures,
including  the  increasing  number of  patients  covered by some form of managed
care. In the past, the Company has offset a substantial portion of the impact of
price  decreases and coverage  changes  through the  achievement of economies of
scale and other  strategies  such as more favorable  purchase  contracts and the
introduction  of  alternative  technologies.  However,  if price  decreases (for
example arising from the proposed  Medicare changes discussed above) or coverage
changes were to be rapidly and fully  implemented,  they would be likely to have
an adverse  impact on gross profits from the Company's  testing  services  until
management was able to mitigate such impact.

      O    SELLING, GENERAL AND ADMINISTRATIVE EXPENSES

Selling,  general and administrative expenses were $6.2 million during the First
Quarter 1997, an increase of $1.2 million or 23% from the First Quarter 1996. As
a percentage  of net  revenues,  selling,  general and  administrative  expenses
decreased to 40% in the First Quarter 1997 from 41% in the First Quarter 1996.

Amortization  expenses  were  $66,000 in the First  Quarter  1997, a decrease of
$2,000 or 4% from the First Quarter 1996.

Severance  costs of  approximately  $159,000  were recorded in the First Quarter
1997. No similar charges were recorded in the First Quarter 1996.

Investment  write-downs  of $4,000 were  recorded in the First  Quarter  1996 to
write-down the investment in common stock of a publicly traded company to market
value as the loss in value was deemed other than  temporary in  accordance  with
the  Statement of Financial  Accounting  Standard 115,  "Accounting  for Certain
Investments on Debt and Equity Securities".  No similar charges were recorded in
the First  Quarter  1997.  The Company  sold its  remaining  shares in the First
Quarter 1997.

      O    RESEARCH AND DEVELOPMENT

Research and  development  expenses  were  $508,000 in the First Quarter 1997, a
decrease  of  $299,000  or  37%  from  the  First  Quarter  1996.  Research  and
development  expenses  include the costs of building the Company's  database and
the  review,  analysis  and  clinical  evaluation  of  existing  as  well as new
technologies.  This decrease in 1997 is primarily due to the  completion in 1996
of the major portion of  expenditures  for the  development  of the new anatomic
pathology  services.  During the First Quarter 1997, the Company reorganized its
research and development technology activities.



      O    INTEREST INCOME

The Company's interest income was $92,000 for the First Quarter 1997, a decrease
of $33,000 or 26% from the First Quarter 1996.  Cash and cash  equivalents as of
March 31, 1997 was $10.0 million of which $8.0 million was invested  compared to
$10.0 million for the comparable period in 1996.

      O    INTEREST EXPENSE

Interest  expense was $11,000 for the First  Quarter 1997, a decrease of $13,000
or 55% from the First Quarter 1996. The decrease in interest  expense was due to
the pay-down of a portion of the $3.5 million term loan obtained in July of 1993
which bears interest at 6% per year.

      O    PROVISION FOR INCOME TAXES

Provision  for income tax expense was $466,000 for the First  Quarter  1997,  an
increase of $249,000 or 114% from the First Quarter 1996. The effective tax rate
was 43% during the First Quarter 1997 and the First Quarter 1996.

      O    NET INCOME

As a result of the foregoing, the First Quarter 1997 net income was $618,000, an
increase of $330,000 or 114% from the First Quarter 1996.

LIQUIDITY AND CAPITAL RESOURCES
- -------------------------------

As of March 31,  1997,  the  Company  had  total  cash and cash  equivalents  of
approximately  $10.0 million which was invested in a fund holding U. S. Treasury
securities with maturities of less than three months.

The Company had working  capital of $17.3  million at March 31, 1997 compared to
$18.1 million at December 31, 1996,  and the working  capital ratio was 3.2 to 1
at March 31, 1997 compared to 3.4 to 1 at December 31, 1996.

Domestic  trade  receivables,  net,  were $13.2  million as of March 31, 1997, a
decrease of $2.1 million or 14% from December 31, 1996. During the First Quarter
1997,  the  average  number of days  sales in  domestic  trade  receivables  was
approximately 82 days as compared to 74 days for the comparable  period of 1996.
The increase in average number of days sales was a result of increased volume in
the Company's  anatomic  pathology testing services and increased  complexity of
billing for anatomic  pathology  testing  services.  The average  number of days
sales has  decreased  from 94 days for the month of December 1996 to 75 days for
the month of March 1997.  This  decrease  was result of  significantly  reducing
domestic accounts receivable from $15.2 million as of December 31, 1996 to $13.2
million as of March 31, 1997.

Capital expenditures during the First Quarter 1997 were approximately $457,000.

In July 1993,  the Company  obtained a $3.5  million  term loan from a bank that
bears  interest  at 6% per year and is payable  over a 47 month  period.  During
1995,  the  term  loan  agreement  was  modified  to  revise  certain  financial
covenants,  including  those with respect to tangible net worth and debt service
coverage requirements and limitation on certain  expenditures.  During the First
Quarter 1997,  there were no changes in the Company's  existing debt agreements.
The  Company has  outstanding  under such term loan  principal  in the amount of
approximately $412,000 as of March 31, 1997.

As of March 31, 1997,  the Company had purchased  334,196 shares of Common Stock
as required by its Employee  Stock  Purchase  Plan  ("ESPP").  During the fourth
quarter of 1996, the Company's Board of Directors  authorized  additional  share
repurchases  costing up to $2.0 million.  As of March 31, 1997,  the Company has
acquired  shares  costing $1.8 million.  In April 1997,  the Company's  Board of
Directors  again  authorized  additional  share  repurchases  costing up to $2.0
million.

The Company believes that cash flows from operations and available cash and cash
equivalents  are adequate to fund the Company's  operations for the  foreseeable
future.



RISK FACTORS; FORWARD LOOKING STATEMENTS
- ----------------------------------------

The  Management's  Discussion and Analysis  contain forward  looking  statements
regarding the  Company's  future plans,  objectives,  and expected  performance.
These  statements  are  based on  assumptions  that  the  Company  believes  are
reasonable,  but are subject to a wide range of risks and  uncertainties,  and a
number of factors could cause the Company's actual results to differ  materially
from those expressed in the forward-looking  statements referred to above. These
factors include,  among others,  the  uncertainties  in reimbursement  rates and
reimbursement  coverage of various tests sold by the Company to beneficiaries of
the Medicare  program;  possibility of being deemed to be not in compliance with
Federal or state  regulatory  requirements;  the  uncertainties  relating to the
ability of the Company to convince  physicians and/or managed care organizations
to use the Company as a provider of anatomic  pathology  testing  services;  the
ability of the Company to maintain superior quality relative to its competitors;
the ability of the Company to maintain its  hospital-based  business in light of
the competitive pressures and changes occurring in hospital healthcare delivery;
the  uncertainties  relating to states  erecting  barriers to the performance of
anatomic  national  laboratories,   small  specialized   laboratories  and  well
established  local  pathologists;  and the  uncertainties  which  would arise if
integrated  delivery systems closed to outside providers emerged as the dominant
form of health care delivery.



PART II OTHER INFORMATION


Item 6      EXHIBITS AND REPORTS ON FORM 8-K
            --------------------------------

           a     Exhibits

                 (11.1)  Statement regarding computation of  per  share earnings
                         is not required because the relevant computation can be
                         determined from the material contained in the Financial
                         Statements included herein.

                 (27.1)  Financial Data Schedule

            b     Report on Form 8-K.  No reports on  Form 8-K were filed during
                  the First Quarter 1997.



Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


                                       DIANON Systems, Inc.


                                       /s/ KEVIN C. JOHNSON
                                       -----------------------------------
           May 9, 1997
                                       By:  Kevin C. Johnson
                                            President and
                                            Chief Executive Officer
                                            (Principal Executive Officer)



                                       /s/ DAVID R. SCHREIBER
                                       -----------------------------------
           May 9, 1997
                                       By:  David R. Schreiber
                                            Senior Vice President, Finance
                                            and Chief Financial Officer
                                            (Principal Financial and
                                            Accounting Officer)



                                  EXHIBIT INDEX

                                                                            PAGE
                                                                            ----

27.1  Financial Data Schedule (filed herewith)                                16