UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 12, 2000 Shire Pharmaceuticals Group plc - -------------------------------------------------------------------------------- (Exact name of registrant as specified in its charter) England and Wales - -------------------------------------------------------------------------------- (State or other jurisdiction of incorporation) 0-29630 N/A - ------------------------------------- ------------------------------------ (Commission File Number) (IRS Employer Identification No.) East Anton, Andover, Hampshire SP10 5RG England - -------------------------------------------------------------------------------- (Address of principal executive offices) (Zip code) Registrant's telephone number, including area code 44-1264-333455 ------------------------------ - -------------------------------------------------------------------------------- (Former name or former address, if changed since last report) -2- Item 7. Financial Statements, Pro Forma Financial Statements and Exhibits (c) Exhibits: 2.1 Merger Agreement, dated as of December 11, 2000, among BioChem Pharma Inc., 3829341 Canada Inc. and Shire Pharmaceuticals Group plc* 10.1 Stock Option Agreement dated as of December 11, 2000 between Shire Pharmaceuticals Group plc and BioChem Pharma Inc.* 99.1 Joint Press Release dated December 11, 2000 - ---------- * Incorporated by reference to Shire's Form 8-K filed on December 11, 2000. -3- SIGNATURE Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Dated: December 12, 2000 SHIRE PHARMACEUTICALS GROUP PLC By: /s/ Angus Russell ----------------------------------------- Angus Russell EXHIBIT INDEX Exhibit Number Description 2.1 Merger Agreement, dated as of December 11, 2000, among BioChem Pharma Inc., 3829341 Canada Inc. and Shire Pharmaceuticals Group plc* 10.1 Stock Option Agreement dated as of December 11, 2000 between Shire Pharmaceuticals Group plc and BioChem Pharma Inc.* 99.1 Joint Press Release dated December 11, 2000 - ---------- * Incorporated by reference to Shire's Form 8-K filed on December 11, 2000.