UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 8-K



                                 CURRENT REPORT


                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


       Date of Report (Date of earliest event reported): September 3, 2003


                         Shire Pharmaceuticals Group plc
________________________________________________________________________________
             (Exact name of registrant as specified in its charter)


                                England and Wales
________________________________________________________________________________
                 (State or other jurisdiction of incorporation)


              0-29630                                     98-0359573
     (Commission File Number)                (IRS Employer Identification No.)

Hampshire International Business Park, Chineham, Basingstoke,
Hampshire RG24 8EP England
________________________________________________________________________________
(Address of principal executive offices)                              (Zip code)

Registrant's telephone number, including area code               44 1256 894 000



________________________________________________________________________________
          (Former name or former address, if changed since last report)




Item 5.  Other Events

     Shire  Pharmaceuticals  Group plc has issued the press release  attached as
Exhibit 99.1 and incorporated by reference herein.

Item 7.  Financial Statements and Exhibits

                  (c)  Exhibits.  The following exhibit is filed herewith:

99.1              Press Release dated September 3, 2003



                                      -2-


                                    SIGNATURE


     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

Dated: September 3, 2003                         SHIRE PHARMACEUTICALS GROUP PLC



                                             By: /s/ A C Russell
                                                 -------------------------------
                                                  Name:  ANGUS RUSSELL
                                                  Title:  Group Finance Director









                                  EXHIBIT INDEX


Number   Description

99.1              Press Release dated September 3, 2003