SUBSCRIPTION AGREEMENT (GFL Performance Fund Limited) THIS SUBSCRIPTION AGREEMENT, dated as of the date of acceptance set forth below, by and between XOMA CORPORATION, a Delaware corporation, with headquarters located at 2910 Seventh Street, Berkeley, California 94710 (the "Company"), and the undersigned (the "Buyer"). W I T N E S S E T H: WHEREAS, the Company and the Buyer are executing and delivering this Agreement in reliance upon the exemption from securities registration afforded by Rule 506 under Regulation D ("Regulation D") as promulgated by the United States Securities and Exchange Commission (the "SEC") under the Securities Act of 1933, as amended (the "1933 Act"); WHEREAS, the Buyer wishes to purchase, upon the terms and subject to the conditions of this Agreement, shares of Common Stock, $.0005 par value, and the related Preferred Stock Purchase Rights (the "Common Stock") of the Company upon the terms and subject to the conditions of this Agreement, subject to acceptance of this Agreement by the Company; and WHEREAS, contemporaneously with the execution and delivery of this Agreement, the Company and Genesee Fund Limited-Portfolio B ("GFL-B") are executing and delivering a Preferred Stock Subscription Agreement (the "GFL-B Subscription Agreement"), providing for the purchase, upon the terms and subject to the conditions provided therein, by GFL-B of shares of non-voting convertible preferred stock of the Company for an aggregate subscription price of $5,000,000.00; NOW THEREFORE, in consideration of the premises and the mutual covenants contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties agree as follows: 1. AGREEMENT TO SUBSCRIBE; PURCHASE PRICE. (a) Subscription. The undersigned hereby agrees to purchase from the Company the numbers of shares (the "Shares") of Common Stock set forth on the signature page of this Agreement; at the price per share and for the aggregate purchase price set forth on the signature page of this Agreement. The purchase price for the Shares shall be payable in United States Dollars. (b) Form of Payment. The Buyer shall pay the purchase price for the Shares by delivering good funds in United States Dollars to the escrow agent identified in the Joint Escrow Instructions attached hereto as Annex I (the "Escrow Agent"). Such delivery of funds shall be made against delivery by the Company of the certificates for the Shares registered in the name of the Buyer. Promptly following payment by the Buyer to the Escrow Agent of the purchase price of the Shares, the Company shall deliver certificates for the Shares, registered in the name of the Buyer, to the Escrow Agent. By signing this Agreement, the Buyer and the Company each agrees to all of the terms and conditions of, and becomes a party to, the Joint Escrow Instructions attached hereto as Annex I, all of the provisions of which are incorporated herein by this reference as if set forth in full. (c) Method of Payment. Payment of the purchase price for the Shares shall be made by wire transfer of funds to: Citibank, N.A. 153 East 53rd Street New York, New York 10043 ABA#021000089 For Further Credit to A/C#37179446 for credit to the account of Brian W. Pusch Attorney Escrow Account Reference: GFL/XOMA Not later than 4:00 p.m., New York City time, on the date which is one New York Stock Exchange trading day after the Company shall have accepted this Agreement and the GFL-B Subscription Agreement and returned a signed counterpart of this Agreement to the Buyer, the Buyer shall deposit with the Escrow Agent the aggregate purchase price for the Shares. 2. BUYER REPRESENTATIONS, WARRANTIES, ETC.; ACCESS TO INFORMATION; INDEPENDENT INVESTIGATION. The Buyer represents and warrants to, and covenants and agrees with, the Company as follows: (a) The Buyer is purchasing the Shares for its own account for investment only and not with a view towards the public sale or distribution thereof; (b) The Buyer is an "accredited investor" as that term is defined in Rule 501 of the General Rules and Regulations under the 1933 Act by reason of Rule 501(a)(3); (c) All subsequent offers and sales of the Shares by the Buyer shall be made pursuant to registration of the Shares being offered and sold under the 1933 Act or pursuant to an exemption from registration; -2- (d) The Buyer understands that the Shares are being offered and sold to it in reliance on specific exemptions from the registration requirements of United States federal and state securities laws and that the Company is relying upon the truth and accuracy of, and the Buyer's compliance with, the representations, warranties, agreements, acknowledgments and understandings of the Buyer set forth herein in order to determine the availability of such exemptions and the eligibility of the Buyer to acquire the Shares; (e) The Buyer and its advisors, if any, have been furnished with all materials relating to the business, finances and operations of the Company and materials relating to the offer and sale of the Shares which have been requested by the Buyer. The Buyer and its advisors, if any, have been afforded the opportunity to ask questions of the Company and have received complete and satisfactory answers to any such inquiries. Without limiting the generality of the foregoing, the Buyer has had the opportunity to obtain and to review the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 1995 (the "1995 Form 10-K"), as filed with the SEC. The Company has not filed any reports or other information with the SEC since December 31, 1995, except the 1995 Form 10-K. The Buyer understands that its investment in the Shares involves a high degree of risk; (f) The Buyer understands that no United States federal or state agency or any other government or governmental agency has passed on or made any recommendation or endorsement of the Shares; (g) This Agreement has been duly and validly authorized, executed and delivered on behalf of the Buyer and is a valid and binding agreement of the Buyer enforceable in accordance with its terms, subject as to enforceability to general principles of equity and to bankruptcy, insolvency, moratorium and other similar laws affecting the enforcement of creditors~ rights generally; and (h) The purchase of the Shares by the Buyer pursuant to this Agreement does not require any governmental or regulatory consent, approval or filing on the part of the Buyer or, to the knowledge of the Buyer, on the part of the Company, under the securities or similar laws of the jurisdiction in which the Buyer's principal executive offices are located. 3. COMPANY REPRESENTATIONS, ETC. The Company represents and warrants to the Buyer that: (a) Concerning the Shares. The Shares have been duly authorized and, when issued and paid for in accordance with this Agreement, will be duly and validly issued, fully paid and non-assessable and will not subject the holder thereof to personal -3- liability by reason of being such holder. There are no preemptive rights of any stockholder of the Company, as such, to acquire the Shares. The Common Stock is listed for trading on the Nasdaq National Market ("Nasdaq") and (1) the Company and the Common Stock meet the criteria for continued listing and trading on Nasdaq; (2) the Company has not been notified since January 1, 1994 by the National Association of Securities Dealers, Inc. of any failure or potential failure to meet the criteria for continued listing and trading of the Common Stock on Nasdaq and (3) no suspension of trading in the Common Stock is in effect; and the filing by the Company of the listing application for the Shares with Nasdaq after the Closing Date (as required by Section 4(e)), rather than prior to the Closing Date, will not have any material adverse effect on the listing of the Common Stock on Nasdaq. (b) Subscription Agreement; Registration Rights Agreement. This Agreement and the Registration Rights Agreement, the form of which is attached hereto as Annex II (the "Registration Rights Agreement"), have been duly and validly authorized by the Company, this Agreement has been duly executed and delivered on behalf of the Company and assuming the due authorization, execution and delivery hereof and thereof by the Buyer, this Agreement is and the Registration Rights Agreement, when executed and delivered by the Company, will be valid and binding agreements of the Company enforceable in accordance with their respective terms, subject as to enforceability to general principles of equity and to bankruptcy, insolvency, fraudulent conveyance, reorganization, moratorium and other similar laws affecting the enforcement of creditors~ rights generally and except that rights to indemnity and contribution may be limited by public policy. (c) Non-contravention. The execution and delivery of this Agreement and the Registration Rights Agreement by the Company and the consummation by the Company of the issuance of the Shares and the other transactions contemplated by this Agreement and the Registration Rights Agreement do not and will not conflict with or result in a breach or violation by the Company of any of the terms or provisions of, or constitute a default under, the certificate of incorporation or by-laws of the Company, or any indenture, mortgage, deed of trust or other material agreement or instrument to which the Company is a party or by which it or any of its properties or assets are bound, or (assuming the representations and warranties of the Buyer in Section 2 hereof and of Michael Arnouse in his option agreement with the Company, a copy of which has been furnished to the Buyer, are true and correct) any applicable law, rule or regulation or any applicable decree, judgment or order of any court, United States federal or state regulatory body, administrative agency or other governmental body having jurisdiction over the Company or any of its properties or assets, which conflict, breach, violation or default could have a material adverse effect on the validity or enforceability of this -4- Agreement, the Registration Rights Agreement or the issuance of the Preferred Shares or the transactions contemplated by this Agreement, the Registration Rights Agreement or the terms of the Preferred Shares or on any right or remedy of the Buyer under this Agreement, the Registration Rights Agreement or the terms of the Preferred Shares; provided, however, that the Company makes no representation or warranty in this Section 3(c) with regard to any law, rule or regulation of any jurisdiction outside the United States or any decree, judgment or order of any court outside the United States having jurisdiction over the Company or any of its properties or assets which law, rule or regulation becomes applicable to the Company or which court acquires jurisdiction over the Company solely by reason of the Buyer's status as a corporation organized under the laws of the British Virgin Islands or headquartered in Curacao, Netherlands Antilles. (d) Approvals. No authorization, approval or consent of, or filing with, any court, governmental body, regulatory agency, self-regulatory organization, or stock exchange or market or the stockholders of the Company is required to be obtained by the Company for the issuance and sale of the Shares as contemplated by this Agreement, other than (1) listing of the Common Shares on Nasdaq, (2) the requirements of any applicable blue sky laws and (3) the filing of a Form D relating to the Shares by the Company with the SEC. (e) Information Provided. The information provided by or on behalf of the Company to the Buyer and referred to in Section 2(e) of this Agreement does not contain any untrue statement of a material fact or omit to state any material fact necessary in order to make the statements therein, in the light of the circumstances under which they are made, not misleading. (f) Absence of Certain Changes. Since December 31, 1995, there has been no material adverse change and no material adverse development in the business, properties, operations, condition (financial or other) or results of operations of the Company, except as disclosed in the documents referred to in Section 2(e) hereof. (g) Absence of Litigation. Except (i) as set forth in the 1995 10-K, (ii) as described in the letter, dated the date hereof, heretofore delivered by the Company to the Buyer, and (iii) for applications and proceedings relating to regulatory approval of new drugs or the granting of patents, there is no action, suit, proceeding, inquiry or investigation before or by any court, public board or body pending or, to the knowledge of the Company or any of its subsidiaries, threatened against or affecting the Company or any of its subsidiaries, wherein an unfavorable decision, ruling or finding would have a material adverse effect on the properties, business, condition (financial or other) or results of operations -5- of the Company and its subsidiaries taken as a whole or the transactions contemplated by this Agreement or any of the documents contemplated hereby or which would materially adversely affect the validity or enforceability of, or the authority or ability of the Company to perform its obligations under, this Agreement or any of such other documents. 4. Certain Covenants and Acknowledgments. (a) Transfer Restrictions. The Buyer acknowledges that (1) the Shares have not been and, except as provided in the Registration Rights Agreement referred to in Section 4(c) of this Agreement, are not being registered under the 1933 Act, and may not be transferred unless (A) subsequently registered thereunder for resale by the holder or (B) the Buyer shall have delivered to the Company an opinion, reasonably satisfactory in form, scope and substance to the Company, of counsel reasonably satisfactory to the Company (which shall include, but not be limited to, counsel who represented the Buyer in connection with the negotiation and execution of this Agreement) to the effect that the Shares to be sold or transferred may be sold or transferred pursuant to an exemption from such registration; (2) any sale of the Shares made in reliance on Rule 144 promulgated under the 1933 Act may be made only in accordance with the terms of said Rule and further, if said Rule is not applicable, any resale of such Shares under circumstances in which the seller, or the person through whom the sale is made, may be deemed to be an underwriter, as that term is used in the 1933 Act, may require compliance with some other exemption under the 1933 Act or the rules and regulations of the SEC thereunder; and (3) neither the Company nor any other person is under any obligation to register the Shares (other than pursuant to the Registration Rights Agreement referred to in Section 4(c) of this Agreement) under the 1933 Act or to comply with the terms and conditions of any exemption thereunder. (b) Restrictive Legend. The Buyer acknowledges and agrees that, until such time as the Shares have been registered under the 1933 Act as contemplated by the Registration Rights Agreement, the certificates for the Shares, may bear a restrictive legend in substantially the following form (and a stop-transfer order may be placed against transfer of the certificates for the Shares until such registration): The securities represented by this certificate have not been registered under the Securities Act of 1933, as amended. The securities have been acquired for investment and may not be sold, transferred or assigned in the absence of an effective registration statement for the securities under the Securities Act of 1933, as amended, or an opinion reasonably satisfactory in form, scope and substance to the Company of counsel reasonably -6- satisfactory to the Company that registration is not required under said Act. (c) Registration Rights Agreement. The parties hereto agree to enter into the Registration Rights Agreement, in the form attached hereto as Annex II, on or before the Closing Date. (d) Form D. The Company agrees to file a Form D with respect to the Shares as required under Regulation D and to provide a copy thereof to the Buyer promptly after such filing. The Buyer agrees to cooperate with the Company in connection with such filing and, upon request of the Company, to provide all information relating to the Buyer required for such filing. (e) Authorization for Trading; Reporting Status. On or before the date which is five days after the Closing Date, the Company shall file a listing application for the Shares with Nasdaq and shall provide evidence of such filing to the Buyer. So long as the Buyer beneficially owns any of the Shares, during the 18 months following the Closing Date the Company shall file all reports required to be filed with the SEC pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended (the "1934 Act"), and during such 18-month period the Company shall not terminate its status as an issuer required to file reports under the 1934 Act even if the 1934 Act or the rules and regulations thereunder would permit such termination. (f) Use of Proceeds. The Company will use the proceeds from the sale of the Shares for the Company's internal working capital purposes and shall not, directly or indirectly, use such proceeds for any loan to or investment in any other corporation, partnership enterprise or other person; provided, however, that nothing in this Section 4(f) shall prohibit the Company from using such proceeds for the acquisition of or investment in businesses, product lines or technologies in the fields of research, development or marketing of pharmaceutical products for the treatment of human and animal diseases and illnesses or from making any loan to any business engaged in such activity and in which the Company owns an interest having a majority of the voting or similar power of such business. (g) Blue Sky Laws. On or before the Closing Date, the Company shall take such action as shall be necessary to qualify, or to obtain an exemption for, the Shares for sale to the Buyer pursuant to this Agreement under such of the securities or "blue sky" laws of jurisdictions in the United States as shall be applicable to the sale of the Shares to the Buyer pursuant to this Agreement. The Company shall furnish copies of all filings, applications, orders and grants or confirmations of exemptions relating to such securities or "blue sky" laws on or prior to the Closing Date. The Buyer agrees to cooperate with the Company in -7- connection with such actions and, upon request of the Company, to provide all information, if any, concerning the Buyer required for such actions. 5. TRANSFER AGENT INSTRUCTIONS Promptly following the delivery by the Buyer to the Escrow Agent of the aggregate purchase price for the Shares in accordance with Section 1(c) hereof, and prior to the Closing Date, the Company will instruct its transfer agent to issue one or more certificates for the Shares, bearing the restrictive legend specified in Section 4(b) of this Agreement prior to registration of the Shares under the 1933 Act, registered in the name of the Buyer as set forth on the signature page of this Agreement or its nominee and in such denominations specified by the Buyer at least one business day prior to the Closing Date. The Company warrants that no instruction other than such instructions referred to in this Section 5 and stop transfer instructions to give effect to Section 4(a) hereof prior to registration of the Shares under the 1933 Act will be given by the Company to the transfer agent with respect to the Shares and that the Shares shall otherwise be freely transferable on the books and records of the Company as and to the extent provided in this Agreement and the Registration Rights Agreement. Nothing in this Section shall affect in any way the Buyer's representations and warranties in Section 2 hereof or the Buyer's obligations and agreement to comply with all applicable securities laws upon resale of the Shares. If the Buyer provides the Company with an opinion of counsel reasonably satisfactory to the Company that registration of a resale by the Buyer of any of the Shares is not required under the 1933 Act and which opinion otherwise meets the requirements of clause (1)(B) of Section 4(a) of this Agreement, the Company shall permit the transfer of such Shares and promptly instruct the Company's transfer agent to issue one or more share certificates in such name and in such denominations as specified by the Buyer. The provisions of Section 3(l) of the Registration Rights Agreement shall supersede this Section 5 once said Section 3(l) becomes applicable. 6. STOCK DELIVERY INSTRUCTIONS. The certificates for the Shares shall be delivered by the Company to the Escrow Agent pursuant to Section 1(b) hereof on a delivery against payment basis at the closing. 7. CLOSING DATE. The date and time of the issuance and sale of the Shares (the "Closing Date") shall be 12:00 noon, New York City time, on the date which is two New York Stock Exchange trading days after the date on which the Buyer has deposited the purchase price for the Shares with the Escrow Agent in accordance with Section 1(c) -8- hereof, or such other mutually agreed to time. The closing shall occur on the Closing Date at the offices of the Escrow Agent. 8. CONDITIONS TO THE COMPANY~S OBLIGATION TO SELL AND ISSUE. The Buyer understands that the Company's obligations to sell the Shares to the Buyer pursuant to this Agreement are conditioned upon: (a) The receipt and acceptance by the Company of this Agreement as evidenced by execution of this Agreement by the Company and the return of an executed copy hereof to the Buyer or its legal counsel; (b) Delivery by the Buyer to the Escrow Agent of good funds as payment in full of an amount equal to the purchase price for the Shares in accordance with Section 1(c) hereof; and (c) The accuracy on the Closing Date of the representations and warranties of the Buyer contained in this Agreement as if made on the Closing Date and the performance by the Buyer on or before the Closing Date of all covenants and agreements of the Buyer required to be performed on or before such Closing Date. 9. CONDITIONS TO THE BUYER~S OBLIGATION TO PURCHASE. The Company understands that the Buyer's obligations to purchase the Shares are conditioned upon: (a) Delivery by the Company to the Escrow Agent of the certificates for the Shares in accordance with this Agreement; (b) The accuracy on the Closing Date of the representations and warranties of the Company contained in this Agreement as if made on the Closing Date and the performance by the Company on or before the Closing Date of all covenants and agreements of the Company required to be performed on or before such Closing Date; (c) Receipt by the Buyer on the Closing Date of an opinion of counsel for the Company, dated the Closing Date, in form, scope and substance reasonably satisfactory to the Buyer, to the effect set forth in Annex III attached hereto; and (d) The closing under the GFL-B Subscription Agreement shall have occurred. 10. GOVERNING LAW; MISCELLANEOUS. This Agreement shall be governed by and interpreted in accordance with the laws of the -9- State of California without regard to principles of conflict of laws. A facsimile transmission of this signed Agreement shall be legal and binding on all parties hereto. The headings of this Agreement are for convenience of reference and shall not form part of, or affect the interpretation of, this Agreement. If any provision of this Agreement shall be invalid or unenforceable in any jurisdiction, such invalidity or unenforceability shall not affect the validity or enforceability of the remainder of this Agreement or the validity or enforceability of this Agreement in any other jurisdiction. This Agreement may be amended only by an instrument in writing signed by the party to be charged with enforcement. Any notices required or permitted to be given under the terms of this Agreement shall be sent by mail or delivered personally (which shall include telephone line facsimile transmission) or by courier and shall be effective five days after being placed in the mail, if mailed, or upon receipt, if delivered personally or by courier, in each case addressed to a party at such party's address shown in the introductory paragraph or on the signature page of this Agreement or such other address as a party shall have provided by notice to the other party in accordance with this provision. The Buyer shall have the right to assign its rights and obligations under this Agreement with respect to the purchase of all or any portion of the Shares to any Permitted Transferee (as herein defined), provided such assignee, by written instrument duly executed by such assignee, assumes all obligations of the Buyer hereunder with respect to the purchase of the portion of the Shares so assigned and makes the same representations and warranties with respect thereto as the Buyer makes in this Agreement, whereupon the Buyer shall be relieved of any further obligations, responsibilities and liabilities with respect to the purchase of all or the portion of the Shares the obligation for the purchase of which has been so assigned. In the case of any such assignment, the Company shall agree in writing with such assignee to make available to such assignee the benefits of the Registration Rights Agreement with respect to the Shares with respect to which the purchase under this Agreement has been so assigned. As used herein, Permitted Transferee means any person who (1) is an "accredited investor" (as defined in Regulation D under the 1933 Act) and (2) is either (A) any one of up to five investment funds for which Genesee Advisers serves as the principal adviser or (B) a person as to whom the Company shall have consented to such assignment, such consent not to be unreasonably withheld (it being understood that a proposed assignment by the Buyer to a competitor or potential competitor of the Company or a person which the Company determines in good faith is accumulating or is likely to accumulate ownership of shares of Common Stock for hostile or unfriendly purposes may constitute a basis for withholding such consent). -10- IN WITNESS WHEREOF, this Agreement has been duly executed by the Buyer or one of its officers thereunto duly authorized as of the date set forth below. NUMBER OF SHARES OF COMMON STOCK: PRICE PER SHARE: AGGREGATE PURCHASE PRICE: $2,000,000.00 NAME OF BUYER: GFL PERFORMANCE FUND LIMITED SIGNATURE ____________________________ Title: _______________________________ Date: ____________________________ Address: c/o CITCO Kaya Flamboyan 9 Curacao, Netherlands Antilles This Agreement has been accepted as of the date set forth below. XOMA CORPORATION By: ________________________ John L. Castello Chairman of the Board, President and Chief Executive Officer Date: _____________________