AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JUNE 26, 1996
                                                 Registration No. 333-03829


                    SECURITIES AND EXCHANGE COMMISSION
                           Washington, DC  20549

              POST-EFFECTIVE AMENDMENT NO. 2 ON FORM F-3* TO

                                 FORM F-4

                     REGISTRATION STATEMENT UNDER THE
                          SECURITIES ACT OF 1933

                           ELAN CORPORATION, plc
            (Exact name of registrant as specified in charter)

     Republic of Ireland                              Not Applicable
(State or other jurisdiction of                       (I.R.S. Employer
incorporation or organization)                        Identification No.)

                            Monksland, Athlone
                   County Westmeath, Republic of Ireland
                              +353-902-95000
            (Address, including zip code, and telephone number,
     including area code, of registrant's principal executive offices)

                             WILLIAM F. DANIEL
                            Monksland, Athlone
                   County Westmeath, Republic of Ireland
                              +353-902-95000
         (Name, address, including zip code, and telephone number,
                including area code, of agent for service)
                             ________________

Approximate date of commencement of proposed sale to the public:  From time
to time after this Registration Statement becomes effective.
                             ________________

            If the only securities being registered on this Form are being
offered pursuant to dividend or interest reinvestment plans, please check
the following box.  /  /


_________________________
*     Filed as a Post-Effective Amendment on Form F-3 to such Form F-4
      Registration Statement pursuant to the provisions of Rule 401(e) and
      the procedure described herein.  See "INTRODUCTORY STATEMENT NOT
      FORMING PART OF PROSPECTUS."


      

            If any of the securities being registered on this
Form are to be offered on a delayed or continuous basis
pursuant to Rule 415 under the Securities Act of 1933, other
than securities offered only in connection with dividend or
interest reinvestment plans, check the following box. /x/

            If this Form is filed to register additional
securities for an offering pursuant to Rule 462(b) under the
Securities Act, please check the following box and list the
Securities Act registration statement number of the earlier
effective registration statement for the same offering. / /

            If this Form is a post-effective amendment filed
pursuant to Rule 462(c) under the Securities Act, check the
following box and list the Securities Act registration
statement number of the earlier effective registration
statement for the same offering. /_/

            If delivery of the prospectus is expected to be made
pursuant to Rule 434, please check the following box. /_/

            The registrant hereby amends this registration
statement on such date or dates as may be necessary to delay
its effective date until the registrant shall file a further
amendment which specifically states that this registration
statement shall thereafter become effective in accordance with
Section 8(a) of the Securities Act of 1933 or until the
registration statement shall become effective on such date as
the Commission, acting pursuant to Section 8(a), may determine.























      

                             Explanatory Note

            The purpose of this amendment is to file Exhibit 4.1
to this Registration Statement (File No. 333-03829).  The
Prospectus included as a part of this Registration Statement
remains unchanged.














































      

                                  Part II

                  Information Not Required in Prospectus

Item 16           Exhibits

Exhibit No.       Description


4.1 -             Amended and Restated Deposit Agreement, dated as
                  of May 17, 1996 among Elan Corporation plc, The
                  Bank of New York, as depositary, and the owners
                  and holders from time to time of the ADRs.

4.2 -             Specimen of American Depositary Receipt,
                  evidencing American Depositary Receipts of Elan
                  (included as part of Exhibit 4.1)

5.1 -             Opinion of McCann FitzGerald with respect to the
                  legality of the securities registered hereby.*

23.1 -            Consent of McCann FitzGerald (included as part
                  of Exhibit 5.1)*

23.2 -            Consent of KPMG Peat Marwick*

23.3 -            Consent of Ernst & Young LLP, independent
                  auditors*

24.1 -            Powers of Attorney*

















_________________________
*     Previously filed.       


      

                                SIGNATURES

            Pursuant to the requirements of the Securities Act of
1933, the registrant certifies that it has reasonable grounds
to believe that it meets all of the requirements for filing on
Form F-3 and has duly caused this Post-Effective Amendment No.
2 to the Registration Statement to be signed on its behalf by
the undersigned, thereunto duly authorized, in the City of
Dublin, Republic of Ireland, on June 26, 1996

                                    ELAN CORPORATION, plc


                                    By:   Thomas G. Lynch        
                                          ---------------------------
                                          Thomas G. Lynch
                                          Chief Financial Officer
                                          Executive Vice President


            Pursuant to the requirements of the Securities Act of
1933, this Amendment No. 1 to the Registration Statement has
been signed by the following persons in the capacities and on
the dates indicated:

        Signatures                Capacity                   Date         
        ----------                --------                   ----


          *
- - ----------------------        Chairman of the Board           June 26, 1996
   Donald E. Panoz



          *
- - ----------------------        Chief Executive                 June 26, 1996
   Donal J. Geaney             Officer/President
                                and Director
                                (Principal
                                Executive Officer)



          
   Thomas G. Lynch
- - ----------------------        Chief Finanical                 June 26, 1996
   Thomas G. Lynch             Officer/Executive
                                Vice President
                                (Principal
                                Financial Officer)



      

        Signatures              Capacity                     Date         
        ----------              --------                     ----



          *
- - --------------------      Executive Vice President           June 26, 1996
  Kenneth W. McVey             and Director



          *
- - --------------------      Group Financial Controller         June 26, 1996
  William F. Daniel            (Principal
                                Accounting Officer)



          *
- - --------------------         Director                        June 26, 1996
 Howard C. Ansel, Ph.D.



          *
- - --------------------         Director                        June 26, 1996
    Garo Armen, Ph.D.



          *
- - --------------------         Director                        June 26, 1996
    James Balog



          *
- - --------------------         Director                        June 26, 1996
    Brendan Boushel



          *
- - --------------------         Director                        June 26, 1996
   Charles Greyston


      

        Signatures              Capacity                     Date         
        ----------              --------                     ----



          *
- - --------------------         Director                        June 26, 1996
  Kevin McIntyre, M.D.



Elan Pharmaceutical Research Corp.
Authorized Representative




   Thomas G. Lynch            Secretary                      June 26, 1996
- - ------------------------
   Thomas G. Lynch


*:    Thomas G. Lynch
      ------------------
      Thomas G. Lynch
       Attorney-in-Fact





























      

                               EXHIBIT INDEX


Exhibit No.       Description


4.1 -             Amended and Restated Deposit Agreement, dated as
                  of May 17, 1996 among Elan Corporation plc, The
                  Bank of New York, as depositary, and the owners
                  and holders from time to time of the ADRs.

4.2 -             Specimen of American Depositary Receipt,
                  evidencing American Depositary Receipts of Elan
                  (included as part of Exhibit 4.1)

5.1 -             Opinion of McCann FitzGerald with respect to the
                  legality of the securities registered hereby.*

23.1 -            Consent of McCann FitzGerald (included as part
                  of Exhibit 5.1)*

23.2 -            Consent of KPMG Peat Marwick*

23.3 -            Consent of Ernst & Young LLP, independent*
                  auditors

24.1 -            Powers of Attorney*



















_________________________
*    Previously filed.