CLOSURE MEDICAL CORPORATION
          COMPUTATION OF NET LOSS PER SHARE
                     (Unaudited)
        (In thousands, except per share data)



                                                 THREE MONTHS ENDED         
                                          MARCH 31,              MARCH 31,  
                                         1999                   1998        
                                         ----                   ----        
                                                                   
Weighted average common shares
   outstanding for the period                 13,304                 13,252 
                                       -------------    ------------------- 
Shares used in computing net loss
   per share- basic and diluted               13,304                 13,252 
                                       -------------    ------------------- 

Net loss                                        (565)  $             (1,956)
                                       -------------    ------------------- 

Net loss per share- basic and diluted          (0.04)  $              (0.15)
                                       -------------    -------------------