Proxymed, Inc.
July 1, 1998
Page 1


                                    Exhibit 5

               MITRANI, RYNOR, ADAMSKY, MACAULAY & ZORRILLA, P.A.
                       2200 SunTrust International Center
                           One Southeast Third Avenue
                              Miami, Florida 33131

                                                        Telephone (305) 358-0050
                                                       Telecopier (305) 358-0550

                                  July 1, 1998


ProxyMed, Inc.
2501 Davie Road
Suite 230
Ft. Lauderdale, Florida  33317

               RE:  PROXYMED, INC. FORM S-3 REGISTRATION STATEMENT

Gentlemen:

         We have acted as counsel to ProxyMed, Inc., a Florida corporation (the
"Company"), in connection with the preparation and filing by the Company with
the Securities and Exchange Commission of a Registration Statement on Form S-3
(the "Registration Statement") under the Securities Act of 1933, as amended. The
Registration Statement relates to an aggregate of 3,708,394 shares of the
Company's common stock, par value $.001 per share, 3,513,416 of which are issued
and outstanding (the "Shares") and 194,978 of which have been reserved for
issuance by the Company to certain of the Selling Shareholders named therein
upon the exercise of certain outstanding warrants (the "Warrant Shares").

         We have examined original, photostatic or certified copies of such
records of the Company, including the Articles of Incorporation, the Bylaws and
minutes, the Registration Statement and other documents as we have deemed
relevant and necessary for purposes of the opinions hereinafter set forth. In
such examination, we have assumed the genuineness of all signatures, the
authenticity of all documents and instruments submitted to us as originals and
the conformity to authentic originals of all documents and instruments submitted
to us as certified or photostatic copies. As to various questions of fact
material to our opinions we have relied upon representations made to us by
various officers and directors of the Company and we have not conducted or
received independent verification of those facts.

         Based on the foregoing, we are of the opinion that (i) the Shares have
been duly and validly authorized and are validly issued, fully paid and
nonassessable and (ii) the Warrant Shares have been duly and validly authorized,
and when the warrants with




Proxymed, Inc.
July 1, 1998
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respect thereto are duly exercised and such Warrant Shares are issued against
payment therefor in accordance with the terms of such warrants, the Warrant
Shares will be validly issued, fully paid and nonassessable.

         We hereby consent to the filing of this opinion as an exhibit to the
Registration Statement and to the use of our name under the caption "Legal
Matters" in the Prospectus forming a part of the Registration Statement. In
giving such consent, we do not admit that we come within the category of persons
whose consent is required by Section 7 of the Securities Act or the Commission's
rules and regulations thereunder.


                                                   Sincerely,



                                                   /s/ MITRANI, RYNOR, ADAMSKY,
                                                       MACAULAY & ZORRILLA, P.A.