SECURITIES AND EXCHANGE COMMISSION
                           WASHINGTON, D.C. 20549

                            AMENDMENT NO. 2
                                 TO
                            SCHEDULE 14D-9

                  Solicitation/Recommendation Statement
                   Pursuant to Section 14(d)(4) of the
                     Securities Exchange Act of 1934

                        FIRST INTERSTATE BANCORP
                       (Name of Subject Company)

                       FIRST INTERSTATE BANCORP
                    (Name of Person Filing Statement)

                    COMMON STOCK, PAR VALUE $2.00 PER SHARE
          (INCLUDING THE ASSOCIATED COMMON STOCK PURCHASE RIGHTS)
                       (Title of Class of Securities)

                                  320548100
                    (CUSIP Number of Class of Securities)

                          WILLIAM J. BOGAARD, ESQ.
                EXECUTIVE VICE PRESIDENT AND GENERAL COUNSEL
                         FIRST INTERSTATE BANCORP
                           633 WEST FIFTH STREET
                           LOS ANGELES, CA 90071
                             (213) 614-3001
           (NAME, ADDRESS AND TELEPHONE NUMBER OF PERSON
           AUTHORIZED TO RECEIVE NOTICE AND COMMUNICATIONS
             ON BEHALF OF THE PERSON FILING STATEMENT)

                               COPY TO:

                          FRED B. WHITE III, ESQ.
                      SKADDEN, ARPS, SLATE, MEAGHER & FLOM
                             919 THIRD AVENUE
                         NEW YORK, NEW YORK 10022
                             (212) 735-3000


               First Interstate Bancorp ("First Interstate") hereby
          amends and supplements its statement on Schedule 14D-9
          initially filed with the Securities and Exchange
          Commission on November 20, 1995, as amended by Amendment
          No. 1 thereto (the "Schedule 14D-9").  Unless otherwise
          indicated herein, each capitalized term used but not
          defined herein shall have the meaning assigned to such
          term in the Schedule 14D-9.

          ITEM 8.   ADDITIONAL INFORMATION TO BE FURNISHED.

               The information set forth in the "Litigation"
          subsection of Item (8) of the Schedule 14D-9 is hereby
          amended and supplemented by the following information:

                    On November 22, 1995, the Los Angeles Superior
          Court granted the defendants' Motion to Stay filed in
          Mesko v. Bryson, et al., (Case No. BC137379).  The Court
          stayed the action pending the final resolution of the
          consolidated class action proceeding in the Delaware
          Chancery Court entitled In re First Interstate Bancorp
          Shareholder Litig., Del. Ch., Consol. C.A. No. 14623 (the
          "Delaware Consolidated Action").   The plaintiff in Mesko
          may move to amend or dissolve this stay if any of the
          three following events occurs: (1) the Delaware
          Consolidated Action does not proceed on behalf of a class
          consisting of all public shareholders of First Interstate
          (the "Class"); (2) the Class is not certified in the
          Delaware Consolidated Action; or (3) if counsel for the
          plaintiff in Mesko files an action in the Delaware
          Chancery Court similar to the action filed in California
          and that action is consolidated with the Delaware
          Consolidated Action, such counsel is not then given the
          opportunity to be actively included in the Delaware
          Consolidated Action.  Counsel for the plaintiff in Mesko
          agreed on the record that the stay also should apply to
          the following cases in which such counsel represents the
          plaintiffs: Eaves v. Bryson, et al., (Case No. BC137380);
          Grill v. Bryson, et al., (Case No. BC137508); Mondschein
          v. Bryson, et al., (Case No. BC137509); Kaplan v. Bryson,
          et al., (Case No. BC138639); Kaplan v. Bryson, et al.,
          (Case No. BC138409); Thornhill v. Bryson, et al., (Case
          No. BC139252).  The parties are currently drafting an
          attorney order for the Court's approval.

                    Two actions have been filed in the United
          States District Court for the Central District of
          California.  The two actions are entitled: Kaplin v.
          Bryson, et al. (Civ. No. 95-7954 RG) and Bradley v.
          Siart, et al. (Civ. No. 95-8047 AAH).  The  Kaplin action
          names the Board of Directors of First Interstate, a
          former First Interstate director,  First Bank System,
          Inc. ("FBS") and FBS' Chairman and Chief Executive
          Officer as defendants.  The action alleges breach of
          fiduciary duty, abuse of control and unjust enrichment.  
          The plaintiff further alleges that FBS and its Chairman
          and Chief Executive Officer aided and abetted the other
          defendants in breaching their fiduciary duties.  The
          plaintiff seeks declaratory relief as well as preliminary
          and permanent injunctive relief enjoining defendants from
          (1) enforcing defensive measures designed to prevent an
          auction, bidding or tender offer for First Interstate;
          and (2) proceeding with the Merger with FBS until the
          value of that transaction can be shown to compare
          favorably with the takeover premium available following
          an auction.  In addition, plaintiff seeks monetary
          damages of an unspecified amount together with
          prejudgment interest and attorneys' and experts' fees.
            
                    The Bradley action names the Board of Directors
          of First Interstate, FBS and Donaldson, Lufkin & Jenrette
          ("DLJ") as defendants.  This complaint alleges that First
          Interstate's directors breached their fiduciary duty by
          entering into the Merger Agreement with FBS and allegedly
          preventing third parties, including Wells Fargo & Company
          ("Wells"),  from acquiring all of First Interstate's
          common stock at a price in excess of the current market
          price.  Plaintiff further alleges that FBS and DLJ aided
          and abetted the other defendants in breaching their
          fiduciary duties.  In addition, this complaint alleges
          violations of sections 14(e) and 14(a) of the Securities
          Exchange Act of 1934, as amended, abuse of control,
          unfair business practices, unjust enrichment and
          constructive fraud.  The plaintiff seeks injunctive
          relief as well as monetary damages of an unspecified
          amount, including punitive damages, together with
          prejudgment interest and attorneys' fees.  The defendants
          intend to defend both actions vigorously.

                    On November 27, 1995, an additional purported
          class action was  filed in the Los Angeles Superior Court
          against the Board of Directors of First Interstate and
          FBS.  The action, entitled Bradley v. Siart, et al. (Case
          No. BC139665), alleges that First Interstate's directors
          breached their fiduciary duty by entering into the Merger
          Agreement with FBS and allegedly preventing third parties
          (including Wells) from acquiring all of First
          Interstate's common stock at a price in excess of the
          current market price.  Plaintiff further alleges that FBS
          aided and abetted the other defendants in breaching their
          fiduciary duties.  In addition, this complaint alleges
          abuse of control, unfair business practices, unjust
          enrichment and constructive fraud.  Plaintiff seeks
          injunctive relief as well as monetary damages of an
          unspecified amount, including punitive damages, together
          with prejudgment interest and attorneys' fees.  The
          defendants intend to defend this action vigorously.

          ITEM 9.   MATERIAL TO BE FILED AS EXHIBITS.

               The following Exhibits are filed herewith:

          Exhibit 39:    Derivative Complaint in Kaplin v. Bryson,
                         et al. (U.S. District Court, Central
                         District of California).

          Exhibit 40:    Complaint in Bradley v. Siart, et al.
                         (California Superior Court).

          Exhibit 41:    Complaint in Bradley v. Siart, et al.
                         (U.S. District Court, Central District of
                         California).

          Exhibit 42:    Complaint in Thornhill v. Bryson, et al.
                         (California Superior Court).


                                  SIGNATURE

               After reasonable inquiry and to the best of its
          knowledge and belief, the undersigned certifies that the
          information set forth in this statement is true, complete
          and correct.

                                   FIRST INTERSTATE BANCORP

                                    By: /s/ William J. Bogaard      
                                        ---------------------------
                                         William J. Bogaard
                                         Executive Vice President
                                         and General Counsel

          Dated:  November 29, 1995