[EXHIBIT 99.4.4]


                                 AMENDMENT

      AMENDMENT, dated as of December 1, 1998 (this "Amendment"), to the
 International Co-Promotion Agreement, effective as of June 28, 1996 (the
 "Agreement") by and between Warner-Lambert Company, a Delaware corporation,
 and Pfizer Inc., a Delaware corporation.

      WHEREAS, Warner-Lambert Company has assigned certain of its rights and
 obligations under the Agreement to Warner-Lambert Export Limited, a company
 organized and existing under the laws of Ireland ("Warner-Lambert"), in
 accordance with the Assignment and Assumption Agreement dated as of
 November 1, 1996; and

      WHEREAS, Pfizer Inc. has assigned certain of its rights and
 obligations under the Agreement to Pfizer Overseas Inc., a corporation
 organized and existing under the laws of Delaware ("Pfizer"), in accordance
 with an Assignment effective as of June 28, 1996;

      WHEREAS, the Agreement has previously been amended by an Amendment and
 Waiver dated as of December 4, 1997 and an Amendment dated as of January
 16, 1998;

      WHEREAS, Warner-Lambert and Pfizer wish to clarify the terms of the
 arrangement for the co-promotion of the Products in China (as hereinafter
 defined) in the event that Warner-Lambert elects, in accordance with an
 Amendment and Waiver dated December 1, 1998 (the "International License
 Amendment") to the International License Agreement effective as of June 28,
 1996 between Warner-Lambert and Pfizer (the "International License
 Agreement"), to co-promote the Products with Pfizer in China (the
 "Election"); and

      WHEREAS, the parties have agreed that as of the effective date of the
 Election certain provisions of the Agreement shall be amended in the manner
 provided for in this Amendment and certain other agreements shall be
 entered into;

      NOW, THEREFORE, the parties hereto hereby agree as follows:

                           ARTICLE I - AMENDMENTS

      SECTION 1.01.  Amendment of Section 1.01.

      Section 1.01 of the Agreement is hereby amended by:

      (a)  adding the following new definition immediately before the
 definition of "Category 1 Countries":

      "Bulk" means the bulk tablet form of Products."

      (b)  adding the following new definition immediately before the
 definition of "Change in Control":

      "Category 4 Country" means China."

      (c)  adding the following new definitions immediately before the
 definition of "Clinical Plan":

      "China" means the People's Republic of China (excluding the Special
 Administrative Region of Hong Kong and Macao)."

      "China Commencement Date" means the date on which Warner-Lambert shall
 commence co-promotion of the Products pursuant to the Election."

      "China Product Expenses" means, for any period, the total of Product
 Expenses, (as that term is defined in the Agreement) incurred by Pfizer and
 Warner-Lambert, in each case for China, during such period."

      "China Co-Promotion Amount" means, for any period, the difference
 between (i) ninety percent (90%) of Net Sales for China during such period
 and (ii) the sum of China Product Expenses and Distribution Expenses for
 China for such period."

      (d)  adding the following new definition immediately before the
 definition of "FDA":

      "Distribution Expenses" for China means, subject to the next sentence,
 the out-of-pocket costs actually paid or credited, by Pfizer or its
 Affiliate, for the order processing, handling, warehousing and physical
 distribution of the Products from (a) Pfizer's  or its Affiliate's plant in
 China to (b) unaffiliated third party customers of the Products which
 customers are not hired by Pfizer or its Affiliate to distribute the
 Products (for purposes of this definition, "Final Customers").
 "Distribution Expenses" shall include without limitation, (i) fees and
 expenses of third parties hired by Pfizer or its Affiliate to process
 orders, handle, warehouse and physically distribute the Products, (ii)
 costs related to the operation of distribution centers and warehouses,
 (iii) freight, shipping and insurance costs to transport the Products from
 Pfizer's or its Affiliate's plant in China to Final Customers, (iv)
 customer and collection services, and (v) order entry and processing costs,
 but shall not include (i) any payments made by third party distributors for
 sales force commissions or sales force incentives, or (ii) any bad debt or
 accounts receivable carrying charges which are not customary in China."

      (e)  amending the definition of "Launch Date" by adding the words ";
 provided, however, that for the purposes of this Agreement, "Launch Date"
 for China means the China Commencement Date" at the end thereof.

      (f)  adding the following new definition immediately before the
 definition of "Market Share":

      "Manufacturing Authorization" means the authorization necessary to
 Package the Products as granted by the relevant Governmental or Regulatory
 Authorities in China."

      (g)  adding the following new definition immediately before the
 definition of "Patents":

      "Packaging" means activities relating to filling/blistering, labeling,
 packaging, and finishing the Products, including but not limited to,
 purchasing packaging materials, quality control, release and storage and
 the tests and analyses conducted in connection therewith."

      (h)  amending the definition of "Net Sales" by:

      (i)  inserting the words "or, in the case of China, the aggregate
           sales of Pfizer and its Affiliates," in the second line after the
           words "Warner-Lambert and its Affiliates";

      (ii) inserting the words "or sales between Pfizer and its Affiliates"
           in the fourth line after the words "Warner-Lambert and its
           Affiliates"; and

     (iii) inserting the words "or, in the case of China, consistent with
           PFIZER's audited financial statements," in the nineteenth line
           after the words "Warner-Lambert's audited financial statements."

      (i)  amending the definition of "Term of this Agreement" by inserting
 the words "(or, with respect to China, the China Commencement Date)" in the
 second line after the words "date hereof".

      SECTION 1.02.  Amendment of Exhibit A.

      Exhibit A of the Agreement is hereby amended by adding a Category 4
 and by inserting the country China under such Category.

      SECTION 1.03.  Amendments of Section 3.01

      (a)  Section 3.01 (b) is hereby amended by inserting the words " and
 (iv) with respect to China, a Category 4 Country, for fifty percent (50%)
 of all Product Expenses and Distribution Expenses", in the eighth line,
 immediately after the first appearance of the word "Expenses," and by
 inserting the words "and Distribution Expenses" in the eighth line,
 immediately after the second appearance of the word "Expenses."

      (b)  Section 3.01 is further amended by adding thereto new subsections
 (c) and (d) providing as follows:

      "(c) For each Agreement Year and separately calculated for China, a
 Category 4 Country, PFIZER shall pay to WARNER-LAMBERT, in local currency,
 fifty percent (50%) of the China Co-Promotion Amount.

      (d)  For purposes of Section 3.01(c), in no event shall PFIZER be
 obligated to pay WARNER-LAMBERT an amount that is greater than forty-five
 percent (45%) of Net Sales in China in any Agreement Year."

      SECTION 1.04.  Amendment of Section 3.02.

      Section 3.02(a) is hereby amended by inserting the words "and (iv) in
 the case of China, a Category 4 Country, for fifty percent (50%) of all
 Product Expenses and Distribution Expenses in the sixth line, immediately
 after the words "Expenses."

      SECTION 1.05   General.

      References to a "Section" or "Sections" herein shall mean the
 relevant Section of this Amendment, unless otherwise noted as referring to
 the relevant Section of the Agreement. Unless otherwise noted, capitalized
 terms used herein shall have the meanings ascribed to them in the
 Agreement.

                       ARTICLE II - ADDITIONAL AGREEMENTS

      SECTION 2.01.  Third Party Sales Force.

      Notwithstanding the terms of Section 2.02 (d) of the Agreement
 relating to the time at which the parties may employ a contract field
 force, it is agreed that at any time after the China Commencement Date,
 each party shall have the right to use the services of a contract sales
 force to promote and detail Products in China, to assist such party in
 satisfying its obligations hereunder or to discharge its promotion and
 detailing obligations hereunder.  In the event that either party grants
 such rights, such party shall (i) exercise effective supervisory control
 over the activities of said third party, and shall (ii) continue to be
 responsible for the third party's performance consistent with the terms and
 conditions of this Amendment and the Agreement.

      SECTION 2.02.  Detailing and Promotional Efforts.

      (a)  It is the intention of the parties that, during each Agreement
 Year with respect to China, each of Warner-Lambert and Pfizer will devote
 substantially equal efforts and internal resources to the marketing,
 promotion and detailing of Products and the other activities contemplated
 under the Agreement. The Marketing Plans developed for China under Section
 4.01 of the Agreement shall reflect the foregoing.  In accordance with
 Section 2.02(b) of the Agreement, if one party is requested to devote its
 resources in excess of its proportionate share, the sharing of the China
 Co-Promotion Amount in accordance with Section 2.06 of this Amendment shall
 take the unequal devotion of resources into account.

      (b)  During each Agreement Year with respect to China, each of Pfizer
 and Warner-Lambert shall be responsible for performing a number of Details
 equal to fifty percent (50%) of the Details designated for such Agreement
 Year in the Marketing Plan then in effect; provided, however, that if one
 party performs more than fifty (50%) of the Details, such efforts shall be
 taken into account in computing the China Co-Promotion Amount to be shared
 in accordance with Section 2.06 of this Amendment.

      SECTION 2.03.  Development of Products; Regulatory Approvals.

      Notwithstanding the provisions of Section 2.04 of the Agreement,  and
 provided that Warner-Lambert has not elected to supply the Product in
 accordance with Section 2.07 below, Pfizer shall exercise reasonable
 efforts to obtain the Marketing Authorization and Price Approval in China
 for a Product with a package insert that is materially equivalent to the
 provisions of Exhibit C to the Agreement.  With respect to China, Pfizer
 shall have the same rights as are provided to Warner-Lambert under the
 terms of Sections 2.04(b) and (c) of the Agreement, subject to conditions
 equivalent to those contained therein.

      SECTION 2.04.  Pfizer Payments.

      (a)  For so long as Pfizer shall enjoy co-promotion rights in China
 under Section 2.01 of the Agreement, and subject the terms of Section
 14.04(b) of the Agreement, Pfizer shall be responsible for fifty percent
 (50%) of all China Product Expenses and fifty percent (50%) of all
 Distribution Expenses for China.  Pfizer shall pay its share of China
 Product Expenses in accordance with the terms set forth in Section 2.06 of
 this Amendment.

      (b)  For each Agreement Year with respect to China, and separately
 calculated for China based in part on Warner-Lambert's notification to
 Pfizer of Warner-Lambert's share of China Product Expenses in accordance
 with Section 2.06 of this Amendment, Pfizer shall pay to Warner-Lambert, an
 amount equal to fifty percent (50%) of the China Co-Promotion Amount.

      SECTION 2.05.  Warner-Lambert Payments.

      For so long as Pfizer shall enjoy co-promotion rights in China under
 Section 2.01 of the Agreement, and subject the terms of Section 14.04(b) of
 the Agreement, Warner-Lambert shall be responsible for fifty percent (50%)
 of all China Product Expenses and fifty percent (50%) of all Distribution
 Expenses for China.  Warner-Lambert shall pay its share of China Product
 Expenses and Distribution Expenses for China in accordance with the terms
 set forth in Section 2.06 of this Amendment.

      SECTION 2.06.  Payments; Payment Reports.

      (a)  Notwithstanding the provisions of Section 3.03 of the Agreement,
 Pfizer shall make payments to Warner-Lambert arising under Section 2.04 of
 this Amendment on a quarterly basis as follows:  for each Agreement Quarter
 relating to China, Pfizer shall pay Warner-Lambert its share of the China
 Co-Promotion Amount pursuant to the procedures set forth in subsections
 (b), (c) and (d) of this Section 2.06.

      (b)  Warner-Lambert shall, within thirty (30) days of (i) the end of
 each Agreement Quarter with respect to China, or (ii) in the event that the
 Agreement is terminated with respect to China pursuant to Section 14.03,
 such termination date, notify Pfizer in writing of the total amount of
 China Product Expenses incurred by Warner-Lambert during such Agreement
 Quarter or shorter period.

      (c)  Provided Warner-Lambert has complied with Section 2.06(b) of this
 Amendment, Pfizer shall, for each Agreement Quarter in each Agreement Year
 relating to China (except for any Agreement Quarter that is the last
 Agreement Quarter with respect to China), within forty-five (45) days of
 the receipt of Warner-Lambert's notice under Section 2.06(b) of this
 Amendment, or, with respect to the last Agreement Quarter in each Agreement
 Year, within ninety (90) days of such receipt, notify Warner-Lambert of the
 calculation of the total amount of China Product Expenses, Distribution
 Expenses for China and Net Sales for China  for such Agreement Quarter, the
 amounts paid or accrued by each of Warner-Lambert or Pfizer, and the
 amounts, if any, payable to each of Pfizer and Warner-Lambert in accordance
 with Sections 2.04, 2.05 and 2.06(a) of this Amendment.

      (d)  Any amount payable by either party with respect to China pursuant
 to the notification under Section 2.06(c) of this Amendment shall be offset
 against any amounts due such party and the net amount shall be paid by
 Pfizer or Warner-Lambert, as the case may be, within ten (10) business days
 after notification by Pfizer pursuant to Section 2.06(c).

      SECTION 2.07.  Manufacturing Authorization; Samples.

      (a)  It is the intention of the parties that during the Term of this
 Agreement Pfizer shall (i) continue to Package the Product from Bulk
 supplied by Warner-Lambert, shall (ii) continue to account for and book the
 sales of the Product in China (except to the extent the parties otherwise
 agree pursuant to Section 2.11 of this Amendment), and (iii)
 notwithstanding the fact that Pfizer shall continue to so Package the
 Product and account for and book sales of the Product in China, that the
 basic economic relationship and legal obligations with respect to co-
 promotion of the Products, as amended hereby, that are established under
 the Agreement shall apply in China.  Notwithstanding the foregoing,
 however, it is agreed that within one (1) year from the date of Election
 ("Supply Election Term"), Warner-Lambert shall have the right, but not the
 obligation, to assume responsibility for the supply of Products within
 China and obtain the Manufacturing Authorization and all other necessary
 related Governmental or Regulatory Approvals.

      In the event that Warner-Lambert elects to assume responsibility for
 the manufacture and sale of Products within China, the Agreement shall be
 revised accordingly and the parties shall enter into such other appropriate
 definitive agreements to effectuate the foregoing intention in accordance
 with the basic economic relationships established in the Agreement and the
 Laws of China.

      In the event of expiration of the Supply Election Term or if Warner-
 Lambert notifies Pfizer of its intention not to exercise the right to
 supply Product as described herein (which it shall do as soon as
 practicable but in any event not later than six (6) months from the
 Election date), Pfizer shall automatically continue to Package and account
 for the sales of the Products, subject to the other provisions of this
 Agreement, for the Term of the Agreement.

      (b)  Until Warner-Lambert exercises its rights as contemplated in
 subparagraph (a) above, if at all, Pfizer's Affiliate in China, Pfizer
 Pharmaceuticals Limited ("Pfizer Dalian") shall have the exclusive right to
 Package the Products based upon the purchase of Bulk from Warner-Lambert in
 compliance with the Manufacturing Authorization, Articles III and V of the
 International License Agreement and this Amendment, subject to Section 2.15
 hereof.

      (c)  Until Warner-Lambert exercises its rights as contemplated in
 subparagraph (a) above, if at all, Pfizer Dalian shall, during each
 Agreement Year relating to China during which Pfizer Dalian Packages the
 Products, provide Warner-Lambert with such quantities of Samples consistent
 with the applicable Marketing Plan for China and the provisions of the
 Agreement to meet Warner-Lambert's reasonable requirements for use in
 accordance with the then current Marketing Plan.

      (d)  The cost per Sample distributed in each Agreement Quarter for
 China shall be calculated as twelve percent (12%) of the quotient of (i)
 Net Sales for China in such Agreement Quarter over (ii) the total number of
 pills of Product sold to unaffiliated third parties in China in such
 Agreement Quarter.

      (e)  Until Warner-Lambert exercises its rights as contemplated in
 subparagraph (a) above, if at all, within thirty (30) days after the end of
 the Term of the Agreement as it relates to China (or, if earlier, the
 termination of Pfizer's co-promotion rights for China), Pfizer and Pfizer
 Dalian shall return, or otherwise dispose of in accordance with
 instructions from Warner-Lambert, all remaining Samples produced by Pfizer
 or Pfizer Dalian for China, if any, and will provide Warner-Lambert with a
 certified statement that all remaining Samples have been returned or
 otherwise properly disposed of and that Pfizer and Pfizer Dalian are no
 longer in possession or control of any such Samples in any form or fashion.
 In addition to the reimbursements provided for under Section 14.06(b) of
 the Agreement, Warner-Lambert shall reimburse Pfizer in respect of purchase
 of Bulk and Packaging costs relating to such Samples.

      (f)  Until Warner-Lambert exercises its rights as contemplated in
 subparagraph (a) above, if at all, Pfizer shall have rights with respect to
 orders and terms of sale in China equivalent to the rights of Warner-
 Lambert under Section 9.01 of the Agreement.

      (g)  If Warner-Lambert exercises its rights as contemplated in
 subparagraph (a) above, at Warner-Lambert's option, Pfizer either shall
 continue customer sales of existing inventories of Products or shall sell
 such existing inventories back to Warner-Lambert at cost.

      SECTION 2.08.  Communication with Regulatory Authorities.

      Warner-Lambert shall grant, pursuant to Section 8.01 of the Agreement,
 Pfizer the right to correspond or communicate with Governmental and
 Regulatory Authorities in China concerning the Products and Atorvastatin
 and to take reasonable actions concerning any authorization or permission
 under which Products are sold or with respect to any application for the
 same; provided, however, that, unless the Law prohibits, Pfizer shall
 provide drafts of any such written correspondence or communications to
 Warner-Lambert for review prior to submission to such authorities.

      SECTION 2.09.  Filings with Governmental or Regulatory Authorities.

      Notwithstanding the provisions of Section 8.02 of the Agreement,
 Pfizer shall have authority and responsibility to maintain and seek
 revisions of the conditions of the Marketing Authorization for the Products
 in China; provided any such revisions are not inconsistent with the
 decisions of the parties as determined in accordance with Section 4.01 of
 the Agreement.  Pfizer shall provide Warner-Lambert for its prior review
 and approval, copies of all submissions to Governmental or Regulatory
 Authorities in China that are intended to revise the conditions of the
 Marketing Authorization, Price Approval or Manufacturing Authorization or
 change or modify the label or labeling for, or the indications of,
 Atorvastatin or any of the Products.

      SECTION 2.10.  Labeling and Promotional Materials.

      Notwithstanding the provisions of Section 8.03 of the Agreement,
 Pfizer shall have authority and responsibility to seek and/or obtain any
 necessary Governmental or Regulatory Authority approvals of any label,
 labeling, package inserts, Product monographs and  Packaging, on
 Promotional Materials used in connection with the Products, and for
 determining whether the same requires Governmental or Regulatory Authority
 approval; provided, however, that no such labels, labeling, package
 inserts, Product monographs and packaging, and Promotional Materials may
 used or distributed by Pfizer unless the same shall be approved in advance
 by the China Country Marketing Team and, for the purposes of determining
 compliance with applicable laws, Warner-Lambert, pursuant to Warner-
 Lambert's internal procedures.

      SECTION 2.11.  Joint Sales Company

       The parties shall determine whether to establish a joint sales
 company or other legal entity within and/or outside of China to accomplish
 the terms and conditions of this Amendment, including with respect to the
 sharing of the China Co-Promotion Amount under Section 2.06 of this
 Amendment. If permitted under the Laws of China, such company or other
 legal entities would have the sole right to (i) receive, accept and fill
 orders of Products in China, (ii) control invoicing, order processing and
 collection of accounts receivable for Product sales, and (iii) record
 Product sales in its books of account. The parties agree to consider and
 negotiate the proposals herein within six (6) months from the date of the
 Election by Warner-Lambert and to prepare a joint recommendation together
 with plans for the implementation of the project ( "Joint Recommendation").

      In the event that, notwithstanding good faith negotiations and the
 preparation of the Joint Recommendation, a party believes that it is
 commercially unreasonable to implement the Joint Recommendation, then it
 shall document the basis therefor (the "Objections") and the final decision
 whether to implement the Joint Recommendation shall be conclusively decided
 by the Global Business Subcommittee within thirty (30) days from the date
 of receipt of the Joint Recommendation and the Objections. The decision of
 the Global Business Subcommittee shall be binding upon each of the parties.

      SECTION 2.12.  Misdirected Orders.

      If, either Pfizer or Warner-Lambert, for any reason, receives orders
 for Products in China, each shall forward such orders to the company or
 entity established in accordance with Section 2.11 of this Amendment (or to
 Pfizer, if applicable) as soon as practicable.

      SECTION 2.13.  Product Returns

      Returned Products in China shall be sent to Pfizer, on terms and
 conditions equivalent to those provided for in Section 9.03 of the
 Agreement.  If a company or entity is established in accordance with
 Section 2.11 of this Amendment, the parties shall agree upon the handling
 of any quantities of Products which are returned to Pfizer or Warner-
 Lambert in China.

      SECTION 2.14.  Supply.

      Until Warner-Lambert exercises its rights as contemplated in Section
 2.07(a), if at all, Pfizer shall use reasonable efforts to supply Products
 (both for trade purposes and Samples) for China during the Term of this
 Agreement as it relates to China in a consistent fashion and in sufficient
 quantities to meet the forecasted amounts of Products in accordance with
 the then current Marketing Plan. With respect to the foregoing, Pfizer
 shall maintain inventory of Products for China equal to three (3) months
 requirements (based on the then current Marketing Plan), so long as Warner-
 Lambert supplies adequate quantities of Bulk for such purposes.  The
 provisions of Section 9.06 of the Agreement shall apply to China with
 respect to Warner-Lambert's obligations to supply Bulk to enable Pfizer to
 supply orders for Products on a timely basis.

      SECTION 2.15.  Pfizer Manufacturing.

      Warner-Lambert shall have the right to visit and audit the facilities
 of Pfizer Dalian during the Term of the Agreement on the same terms as are
 provided in Section 5.04 of the International License Agreement.  Pfizer
 Dalian shall be responsible for filing all submissions or other
 correspondence with the applicable Governmental or Regulatory Authorities
 for China to obtain the Manufacturing Authorization, provided, however,
 that Warner-Lambert shall have the right to review such submissions or
 correspondence prior to filing.

      SECTION 2.16.  Failure of Supply

      In the event that for any reason, including Force Majeure, Pfizer
 shall be unable to supply on a timely basis orders for Product in China,
 Warner-Lambert shall have the right to supply fully finished imported
 Product to customers in China to the extent necessary, during the period in
 which Pfizer is unable to so supply, to fill such orders that Pfizer is
 unable to fill.

      SECTION 2.17.  Pfizer Covenant.

      Pfizer hereby covenants and agrees that any Products to be distributed
 in China during the Term of the Agreement as it relates to China which
 Products have been  Packaged in China will, at the time of shipment by or
 on behalf of Pfizer, not be misbranded or adulterated under the terms of
 applicable Laws as a result of actions or omissions of Pfizer.

      SECTION 2.18.  Other Agreements.

      (a)  Until such time, if at all, as Warner-Lambert exercises its
 rights under Section 2.07(a) to manufacture and sell the Products in China,
 Section 8.07 of the Agreement shall not apply to China, provided that
 Pfizer shall obtain Warner-Lambert's prior written approval before carrying
 out any recall, market withdrawal or other corrective action related to the
 Products.

      (b)  Notwithstanding the terms of Section 8.04 of the Agreement,
 Pfizer shall have the right to handle complaints with respect to the
 Products in China.

      (c)  The provisions of Section 4.01(a) - (c) and (d)(ii) - (v) of the
 International License Agreement shall apply to the supply of Bulk by
 Warner-Lambert to Pfizer during effectiveness of this Amendment.

      (d)  With respect to activity in or affecting China, Pfizer and
 Warner-Lambert shall each indemnify, defend and hold harmless the other as
 provided in and subject to the terms of Sections 4.03 and 4.04 of the
 International Collaboration Agreement dated June 28, 1996 between Warner-
 Lambert Company and Pfizer Inc.

      SECTION 2.19.  Financial Records.

      Pfizer shall keep such records of Net Sales, China Product Expenses
 and Distribution Expenses for China, and Warner-Lambert shall keep such
 records of China Product Expenses, in each case as are necessary to
 determine accurately under United States generally accepted accounting
 principles the China Co-Promotion Amount and the sums due to Pfizer and
 Warner-Lambert under this Amendment.

      The parties shall deduct from any payments required under this
 Amendment those taxes which each of them may be required by the Laws to
 withhold and pay, if at all, and each party shall promptly submit to the
 other evidence of such payments. The parties agree to furnish each other
 with such assistance as reasonably necessary to enable the parties to claim
 corresponding tax exemptions or tax credits, as the case may be.

      SECTION 2.20.  Term.

      The Agreement with respect to China shall expire on the last day of
 Agreement Year Five.  With respect to China, all references in the
 Agreement to "Agreement Year Ten" shall mean Agreement Year Five.

      SECTION 2.21.  Termination of Co-Promotion Rights.

      (a)  Warner-Lambert shall have the right to terminate the Agreement
 with respect to China pursuant to Section 14.02(b) at any time during the
 Term of the Agreement as it relates to China, notwithstanding the
 provisions of Section 14.02(b)(iii) of the Agreement.  In the event that
 Warner-Lambert exercises its right to terminate Pfizer's co-promotion
 rights with respect to China pursuant to Section 14.02(b) of the Agreement,
 Warner-Lambert shall pay to Pfizer (in lieu of the amount described in
 Section 14.04(b) of the Agreement), for each Agreement Year for China which
 would have been remaining had Warner-Lambert not exercised its right to
 terminate, an amount equal to seventy-five (75%) of the difference between
 (a) the China Co-Promotion Amount for such Agreement Year and (b) one-half
 (1/2) of the total China Product Expenses for such Agreement Year.  In
 computing the amounts payable to Pfizer in accordance with the foregoing,
 it shall be assumed that Pfizer shall have no obligation to actually pay or
 incur any China Product Expenses after Pfizer's co-promotion rights are
 terminated under Section 14.02(b).  It is understood that payments for each
 such remaining Agreement Year with respect to China shall be based on the
 actual Net Sales for China and China Product Expenses, in each case for
 such Agreement Year as provided in the Agreement.  It is agreed that the
 last three sentences of Section 14.04(b) of the Agreement shall apply in
 the event that Warner-Lambert exercises its aforedescribed rights in this
 Section 2.21.

      (b)  In the event that Warner-Lambert exercises its right to terminate
 the Agreement with respect to China pursuant to Section 14.02(b) of the
 Agreement and makes the payments as described above, Warner-Lambert shall,
 in addition, continue to make the payments to Pfizer pursuant to Section
 7.02 of the International License Agreement, as amended by the
 International License Amendment in Section 2.11.

                         ARTICLE III - MISCELLANEOUS

      SECTION 3.01.  No Other Amendments; Confirmation.  Except as expressly
 amended, waived, modified and supplemented hereby, the provisions of the
 Agreement, as amended to date, are and shall remain in full force and
 effect.

      SECTION 3.02.  Governing Law.  This Amendment shall be governed by and
 construed in accordance with the law of the State of New York.

      SECTION 3.03.  Headings.  The headings used in this Amendment have
 been inserted for convenience of reference only and do not define or limit
 the provisions hereof.

      SECTION 3.04.  Third Party Beneficiaries.  None of the provisions of
 this Amendment shall be for the benefit of or enforceable by any third
 party, including, without limitation, any creditor of either party hereto.
 No such third party shall obtain any right under any provision of this
 Amendment or shall by reason of any such provision make any claim in
 respect of any debt, liability or obligation (or otherwise) against either
 party hereto.

      IN WITNESS WHEREOF, the parties hereto, by their duly authorized
 officers, have executed this Amendment as of the date first written above.


 WARNER-LAMBERT           PFIZER OVERSEAS INC.
 EXPORT LIMITED


 By: /s/ Paul V. Breen                By: /s/ Mohand Sidi Said
    --------------------------           ------------------------------
 Name:  Paul V. Breen                 Name:  Mohand Sidi Said
 Title: Managing Director             Title: Vice President