THE SECURITIES REPRESENTED BY THIS CERTIFICATE MAY NOT BE SOLD OR OTHERWISE
     DISPOSED  OF  IN  THE  ABSENCE  OF  AN  EFFECTIVE  REGISTRATION  UNDER  THE
     SECURITIES  ACT OF 1933,  AS  AMENDED  (THE  "ACT")  AND  APPLICABLE  STATE
     SECURITIES  LAWS,  OR AN OPINION OF COUNSEL THAT SUCH  REGISTRATION  IS NOT
     REQUIRED UNDER THE ACT AND THE RULES AND REGULATIONS PROMULGATED THEREUNDER
     OR UNDER APPLICABLE  STATE  SECURITIES LAWS AND THAT SUCH  REGISTRATION HAS
     BEEN EFFECTED.

                               THERMOGENESIS CORP.
                               WARRANT CERTIFICATE

CertNumber of Warrants:


     This warrant certificate ("Warrant  Certificate")  certifies that for value
received ______________ or registered assigns (the "Holder") is the owner of the
number of warrants  ("Warrants")  specified  above,  each of which  entitles the
Holder thereof to purchase, at any time following  registration of the shares of
common stock underlying the warrant with the Securities and Exchange Commission,
but  before  the  Expiration  Date  (hereinafter  defined)  one  fully  paid and
non-assessable  share of Common  Stock,  $.001 par value  ("Common  Stock"),  of
ThermoGenesis  Corp.,  a  Delaware  corporation  (the  "Company"),   having  its
principal place of business at 3146 Gold Camp Drive, Rancho Cordova,  California
95670 at a purchase  price of $2.88 per share of Common Stock in lawful money of
the United  States of America in cash or by certified  or  cashier's  check or a
combination of cash and certified or cashier's  check,  subject to adjustment as
hereinafter provided.

     1.  Warrant;  Purchase  Price.  Each  Warrant  shall  entitle the Holder to
purchase one share of Common Stock of the Company and the purchase price payable
upon  exercise  of the  Warrants  shall  initially  be $2.88 per share of Common
Stock, subject to adjustment as hereinafter provided (the "Purchase Price"). The
Purchase  Price and number of shares of Common Stock  issuable  upon exercise of
each Warrant are subject to adjustment as provided in Section 7.

     2. Exercise; Expiration Date.

     2.1 The Warrants are exercisable,  at the option of the Holder, at any time
after  registration of the underlying shares of Common Stock with the Securities
and Exchange  Commission and on or before the Expiration Date, upon surrender of
this Warrant Certificate to the Company together with a duly completed Notice of
Exercise,  in the form  attached  hereto as Exhibit A, and  payment of an amount
equal to the Purchase Price times the number of Warrants to be exercised. In the
case of  exercise  of less than all the  Warrants  represented  by this  Warrant
Certificate, the Company shall cancel the Warrant Certificate upon the surrender
thereof and shall execute and deliver a new Warrant  Certificate for the balance
of such Warrants.

     2.2 The term  "Expiration  Date" shall mean 5:00 p.m. (PST) April 27, 2006,
or if such date shall be a holiday  or a day on which  banks are  authorized  to
close,  then 5:00 p.m. (PST) the next following date which is not a holiday or a
day on which banks are not authorized to close.

     3. Company's Right to Redeem Warrants.

     None.




     4. Registration and Transfer on Company Books.

     4.1 The Company shall maintain books for the  registration  and transfer of
the  Warrants  and the  registration  and transfer of the shares of Common Stock
issued upon exercise of the Warrants.

     4.2 Prior to due presentment  for  registration of transfer of this Warrant
Certificate, or the shares of Common Stock issued upon exercise of the Warrants,
the  Company  may deem and treat the  registered  Holder as the  absolute  owner
thereof.

     4.3 Holder (i) acknowledges that the securities represented by this Warrant
Certificate are not registered under the Securities Act of 1933 ("1933 Act") and
that the  securities  must be held  indefinitely  unless  they are  subsequently
registered  under the 1933 Act or an exemption from  registration  is available,
(ii) is aware that any routine sales of the securities  under Rule 144 under the
1933 Act may be made only in limited  amounts and in  accordance  with the terms
and  conditions  of that  Rule  and  that in such  cases  where  the Rule is not
applicable,  compliance with some other registration exemption will be required,
(iii) is aware that Rule 144 is not  presently  available  for use by Holder for
resale of any such  securities  and that there can be no assurance that Rule 144
will be  available  at any time in the  future,  (iv) is aware  that,  except as
provided  in  Section  5 of the Unit  Purchase  Agreement,  the  Company  is not
obligated to register under the 1933 Act any sale, transfer or other disposition
of the  Securities,  (v) is aware  that the  Company  shall not be  required  to
register the transfer of the  securities on the books of the Company  unless the
Company shall have been provided with an opinion of counsel  satisfactory  to it
prior to such transfer to the effect that registration under the 1933 Act or any
applicable  state  securities  law  has  been  effected  or is not  required  in
connection  with the transaction  resulting in such transfer,  and (vi) is aware
that the securities,  and each  certificate  representing the securities and any
shares of Common Stock or other securities  issued in respect of such securities
upon any stock split, stock dividend, recapitalization, merger, consolidation or
similar event, shall (unless otherwise permitted by this Section 4.3) be stamped
or otherwise imprinted with the following legend:

     "THE  SECURITIES  REPRESENTED  BY  THIS  CERTIFICATE  MAY  NOT BE  SOLD  OR
OTHERWISE  DISPOSED OF IN THE  ABSENCE OF AN  EFFECTIVE  REGISTRATION  UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE "ACT") AND APPLICABLE  STATE  SECURITIES
LAWS, OR AN OPINION OF COUNSEL THAT SUCH  REGISTRATION IS NOT REQUIRED UNDER THE
ACT AND THE RULES AND  REGULATIONS  PROMULGATED  THEREUNDER OR UNDER  APPLICABLE
STATE SECURITIES LAWS AND THAT SUCH REGISTRATION HAS BEEN EFFECTED."

The  restrictions  on the  transferability  of the  securities  shall  cease and
terminate when such securities shall have been registered under the 1933 Act and
are proposed to be sold or otherwise  disposed of in accordance with an intended
method of  disposition  by the  Holder  thereof  set  forth in the  registration
statement  covering  such  securities  or  any  other  applicable   registration
statement,  or when such  securities  are  transferable  in accordance  with the
provisions  of  Rule  144(k)  promulgated  under  the  1933  Act.  Whenever  the
restrictions on transfer shall terminate as hereinabove provided with respect to
any of the securities,  the Holder of any such securities bearing the legend set
forth in this  Section  4.3 as to which such  conditions  shall have  terminated
shall be entitled to receive from the Company,  without  expense (except for the
payment of any applicable  transfer tax) and as expeditiously  as possible,  new
stock certificates not bearing such legend.




     4.4 The Company will provide a legal opinion from an attorney,  as required
in Section 4.3, at the  Company's  expense,  if the  Company's  General  Counsel
reasonably  believes the proposed transfer is exempt from registration under the
Securities Act of 1933, as amended,  and under all applicable  state  securities
laws.

     5. Reservation of Shares.  The Company  covenants that it will at all times
reserve and keep  available out of its authorized  Common Stock,  solely for the
purpose of issue upon exercise of the Warrants,  such number of shares of Common
Stock as shall then be issuable upon the exercise of all  outstanding  Warrants.
The Company  covenants  that all shares of Common  Stock which shall be issuable
upon  exercise of the Warrants  shall be duly and validly  issued and fully paid
and  non-assessable  and free from all taxes,  liens and charges with respect to
the issue  thereof,  and that upon  issuance such shares shall be listed on each
national securities  exchange,  if any, on which the other shares of outstanding
Common Stock of the Company are then listed.

     6. Loss or Mutilation.  Upon receipt by the Company of reasonable  evidence
of the  ownership  of and the loss,  theft,  destruction  or  mutilation  of any
Warrant Certificate and, in the case of loss, theft or destruction, of indemnity
reasonably  satisfactory  to the Company,  or, in the case of  mutilation,  upon
surrender and  cancellation of the mutilated  Warrant  Certificate,  the Company
shall execute and deliver in lieu thereof a new Warrant Certificate representing
an equal number of Warrants.

     7. Adjustment of Purchase Price and Number of Shares Deliverable.

     7.1 The number of shares of Common Stock  purchasable  upon the exercise of
each Warrant  (such  shares being  referred to in this Section 7 as the "Warrant
Shares")  and the  Purchase  Price with  respect to the Warrant  Shares shall be
subject to adjustment as follows:

     In case the Company shall (i) declare a dividend or make a distribution  on
its Common Stock  payable in shares of its capital  stock,  (ii)  subdivide  its
outstanding  shares of Common  Stock  through  stock split or  otherwise,  (iii)
combine its  outstanding  shares of Common Stock into a smaller number of shares
of  Common  Stock,  or  (iv)  issue  by  reclassification  of its  Common  Stock
(including  any such  reclassification  in connection  with a  consolidation  or
merger in which the Company is the continuing  corporation)  other securities of
the  Company,  the number  and/or  nature of  Warrant  Shares  purchasable  upon
exercise of each Warrant immediately prior thereto shall be adjusted so that the
Holder  shall be entitled  to receive  the kind and number of Warrant  Shares or
other  securities of the Company which he would have owned or have been entitled
to receive after the happening of any of the events  described  above,  had such
Warrant been exercised  immediately  prior to the happening of such event or any
record date with respect thereto.  An adjustment made pursuant to this paragraph
(a) shall become effective retroactively as of the record date of such event.

     In the event of any capital  reorganization or any  reclassification of the
capital  stock of the Company or in case of the  consolidation  or merger of the
Company with another  corporation (other than a consolidation or merger in which
the outstanding  shares of the Company's  Common Stock are not converted into or
exchanged for other rights or interests),  or in the case of any sale,  transfer
or other  disposition  to another  corporation of all or  substantially  all the
properties  and  assets  of the  Company,  the  Holder  of  each  Warrant  shall
thereafter  be  entitled  to  purchase  (and  it  shall  be a  condition  to the
consummation  of  any  such  reorganization,  reclassification,   consolidation,
merger, sale, transfer or other disposition that appropriate provisions shall be
made so that such Holder shall  thereafter be entitled to purchase) the kind and
amount of shares of stock and other  securities  and property  (including  cash)
which the Holder  would have been  entitled  to receive had such  Warrants  been
exercised  immediately  prior  to the  effective  date of  such  reorganization,




reclassification,  consolidation,  merger,  sale, transfer or other disposition;
and in any such case appropriate adjustments shall be made in the application of
the provisions of this Section 7 with respect to rights and interest  thereafter
of the Holder of the Warrants to the end that the  provisions  of this Section 7
shall thereafter be applicable, as near as reasonably may be, in relation to any
shares  or  other  property  thereafter  purchasable  upon the  exercise  of the
Warrants.  The  provisions  of this  Section  7.1(b)  shall  similarly  apply to
successive reorganizations,  reclassifications,  consolidations, mergers, sales,
transfers or other dispositions.

     7.2  In  the  event  the  Company  shall  declare  a  dividend,  or  make a
distribution  to the  holders of its Common  Stock  generally,  whether in cash,
property  or assets of any kind,  including  any  dividend  payable  in stock or
securities of any other issuer owned by the Company (excluding regularly payable
cash dividends declared from time to time by the Company's Board of Directors or
any dividend or distribution  referred to in Section 7.1(a) above), the Purchase
Price of each  Warrant  shall be  reduced,  without  any  further  action by the
parties hereto, by the Per Share Value (as hereinafter defined) of the dividend.
For purposes of this  Section  7.2, the "Per Share Value" of a cash  dividend or
other  distribution shall be the dollar amount of the distribution on each share
of Common Stock and the "Per Share Value" of any dividend or distribution  other
than cash shall be equal to the fair market value of such non-cash  distribution
on each share of Common Stock based on market quotation for if available,  or as
determined  in good faith by the Board of  Directors of the Company if no market
quotation is available.

     7.3 No adjustment  in the number of Warrant  Shares  purchasable  under the
Warrants,  or in the Purchase Price with respect to the Warrant Shares, shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least 1% in the number of Warrant  Shares  issuable  upon the  exercise  of such
Warrant,  or  in  the  Purchase  Price  thereof;  provided,  however,  that  any
adjustments  which by reason of this  Section  7.3 are not  required  to be made
shall be carried  forward and taken into account in any  subsequent  adjustment.
All final  results  of  adjustments  to the  number of  Warrant  Shares  and the
Purchase Price thereof shall be rounded to the nearest one thousandth of a share
or the  nearest  cent,  as the case may be.  Anything  in this  Section 7 to the
contrary  notwithstanding,  the  Company  shall be  entitled,  but  shall not be
required,  to make such changes in the number of Warrant Shares purchasable upon
the exercise of each Warrant,  or in the Purchase Price thereof,  in addition to
those required by such Section,  as it in its discretion  shall  determine to be
advisable in order that any dividend or  distribution in shares of Common Stock,
subdivision, reclassification or combination of shares of Common Stock, issuance
of rights,  warrants or options to purchase  Common Stock,  or  distribution  of
shares of stock other than Common  Stock,  evidences of  indebtedness  or assets
(other than  distributions  of cash out of retained  earnings) or convertible or
exchangeable  securities  hereafter  made by the  Company to the  holders of its
Common  Stock shall not result in any tax to the holders of its Common  Stock or
securities convertible into Common Stock.

     7.4 Whenever the number of Warrant Shares  purchasable upon the exercise of
each Warrant or the Purchase Price of such Warrant Shares is adjusted, as herein
provided,  the Company  shall mail to the  Holder,  at the address of the Holder
shown on the books of the Company,  a notice of such  adjustment or adjustments,
prepared and signed by the Chief Financial  Officer or Secretary of the Company,
which sets forth the number of Warrant Shares  purchasable  upon the exercise of
each  Warrant  and  the  Purchase  Price  of  such  Warrant  Shares  after  such
adjustment,  a brief  statement of the facts  requiring such  adjustment and the
computation by which such adjustment was made.

     7.5 In the event that at any time prior to the  expiration  of the Warrants
and prior to their exercise:



     (a) the Company shall declare any distribution  (other than a cash dividend
or a dividend  payable in  securities  of the Company with respect to the Common
Stock); or

     (b) the Company shall offer for  subscription  to the holders of the Common
Stock  any  additional  shares  of stock of any  class or any  other  securities
convertible into Common Stock or any rights to subscribe thereto; or

     (c) the Company shall declare any stock split, stock dividend, subdivision,
combination,   or  similar  distribution  with  respect  to  the  Common  Stock,
regardless of the effect of any such event on the  outstanding  number of shares
of Common Stock; or

     (d) the Company shall declare a dividend,  other than a dividend payable in
shares of the Company's own Common Stock; or

     (e) there shall be a voluntary or involuntary dissolution,  liquidation, or
winding  up of the  Company  (other  than in  connection  with a  consolidation,
merger, or sale of all or substantially all of its property, assets and business
as an entity);

(each such event hereinafter being referred to as a "Notification  Event"),  the
Company  shall cause to be mailed to the Holder,  not less than thirty (30) days
prior to the record date, if any, in  connection  with such  Notification  Event
(provided,  however,  that if there is no record  date,  or if thirty  (30) days
prior notice is impracticable, as soon as practicable) written notice specifying
the  nature of such  event and the  effective  date of, or the date on which the
books of the  Company  shall close or a record  shall be taken with  respect to,
such event. Such notice shall also set forth facts indicating the effect of such
action (to the extent  such  effect may be known at the date of such  notice) on
the  Purchase  Price  and the kind and  amount  of the  shares of stock or other
securities or property  deliverable upon exercise of the Warrants.  For purposes
hereof,  a business day shall mean any day other than a Saturday,  Sunday or any
other day in which commercial banks are authorized by law to be closed.

     7.6 The form of  Warrant  Certificate  need not be  changed  because of any
change in the Purchase  Price,  the number of Warrant  Shares  issuable upon the
exercise  of a Warrant or the number of  Warrants  outstanding  pursuant to this
Section 7, and Warrant Certificates issued before or after such change may state
the same  Purchase  Price,  the same number of Warrants,  and the same number of
Warrant  Shares  issuable upon exercise of Warrants as are stated in the Warrant
Certificates  theretofore  issued pursuant to this  Agreement.  The Company may,
however,  at any time,  in its sole  discretion,  make any change in the form of
Warrant  Certificate  that it may deem  appropriate and that does not affect the
substance   thereof,   and  any  Warrant   Certificates   thereafter  issued  or
countersigned,  whether in exchange or substitution  for an outstanding  Warrant
Certificate or otherwise, may be in the form as so changed.

     8. Conversion Rights.

     Omitted.

     9. Voluntary  Adjustment by the Company. The Company may, at its option, at
any time during the term of the Warrants, reduce the then current Purchase Price
to any amount deemed appropriate by the Board of Directors of the Company and/or
extend the date of the expiration of the Warrants.

     10.  Fractional  Shares and  Warrants;  Determination  of Market  Price Per
Share.



     10.1 Anything contained herein to the contrary notwithstanding, the Company
shall not be  required  to issue  any  fraction  of a share of  Common  Stock in
connection with the exercise of Warrants.  Warrants may not be exercised in such
number as would result  (except for the  provisions  of this  paragraph)  in the
issuance  of a  fraction  of a share  of  Common  Stock  unless  the  Holder  is
exercising  all Warrants  then owned by the Holder.  In such event,  the Company
shall,  upon the  exercise  of all of such  Warrants,  issue to the  Holder  the
largest aggregate whole number of shares of Common Stock called for thereby upon
receipt of the  Purchase  Price for all of such  Warrants  and pay a sum in cash
equal to the remaining  fraction of a share of Common  Stock,  multiplied by its
Market Price Per Share (as determined  pursuant to Section 10.2 below) as of the
last  business day  preceding  the date on which the Warrants are  presented for
exercise.

     10.2 As used herein,  the "Market Price Per Share" with respect to any date
shall mean the closing price per share of Company's Common Stock for the trading
day  immediately  preceding such date. The closing price for each such day shall
be the last sale price  regular way or, in case no such sale takes place on such
day, the average of the closing bid and asked prices regular way, in either case
on the principal  securities exchange on which the shares of Common Stock of the
Company are listed or admitted  to trading,  the last sale price,  or in case no
sale takes place on such day, the average of the closing bid and asked prices of
the Common Stock on NASDAQ or any comparable  system,  or if the Common Stock is
not reported on NASDAQ, or a comparable  system,  the average of the closing bid
and asked  prices as furnished  by two members of the  National  Association  of
Securities  Dealers,  Inc.  selected  from time to time by the  Company for that
purpose. If such bid and asked prices are not available,  then "Market Price Per
Share" shall be equal to the fair market value of the Company's  Common Stock as
determined in good faith by the Board of Directors of the Company.

     11.  Governing  Law.  This  Warrant  Certificate  shall be  governed by and
construed in accordance with the laws of the State of Delaware.





                                [Remainder of Page Left Blank]






     IN WITNESS WHEREOF,  the Company has caused this Warrant  Certificate to be
duly executed by its officers  thereunto duly  authorized and its corporate seal
to be affixed hereon, as of this 27th day of April, 2001.


                                         THERMOGENESIS CORP.



                                         By:
                                              ----------------------------
                                             Philip H. Coelho
                                             Chief Executive Officer

[SEAL]



Attest:


David C. Adams, Secretary







                                    EXHIBIT A


                               NOTICE OF EXERCISE


     The undersigned hereby irrevocably elects to exercise,  pursuant to Section
2 of the  Warrant  Certificate  accompanying  this Notice of  Exercise,  _______
Warrants of the total number of Warrants  owned by the  undersigned  pursuant to
the accompanying Warrant Certificate, and herewith makes payment of the Purchase
Price of such shares in full.




                                                       Name of Holder



                                                       Signature

                                                       Address: