Exhibit 32.1


                    STATEMENT OF CHIEF EXECUTIVE OFFICER AND
           CHIEF FINANCIAL OFFICER PURSUANT TO 18 U.S.C. SECTIION 1350

     In connection  with the Quarterly  Report on Form 10-Q for the period ended
March 31, 2008 (the "Form 10-Q") of Grayson  Bankshares,  Inc. (the  "Company"),
we, Jacky K.  Anderson,  Chief  Executive  Officer of the Company,  and Blake M.
Edwards,  Chief Financial Officer of the Company,  hereby certify pursuant to 18
U.S.C.  Section 1350, as adopted  pursuant to Section 906 of the  Sarbanes-Oxley
Act of 2002, that, to our knowledge:

          (a) the Form 10-Q  fully  complies  with the  requirements  of Section
          13(a) of the Securities Exchange Act of 1934, as amended; and

          (b) the information contained in the Form 10-Q fairly presents, in all
          material respects,  the financial  condition and results of operations
          of the Company as of and for the periods presented in the Form 10-Q.



         By:      /s/ Jacky K. Anderson              Date:  May 15, 2008
                  Jacky K. Anderson
                  Chief Executive Officer



         By:      /s/Blake M. Edwards                Date:  May 15, 2008
                  Blake M. Edwards
                  Chief Financial Officer