Item 1. Report to Shareholders T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- June 30, 2004 Certified Semiannual Report This report is certified under the Sarbanes-Oxley Act of 2002, which requires that public companies, including mutual funds, affirm that the information provided in their annual and semiannual shareholder reports fully and fairly represents their financial position. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report (Unaudited) FINANCIAL HIGHLIGHTS For a share outstanding throughout each period - -------------------------------------------------------------------------------- 6 Months Year Ended Ended 6/30/04 12/31/03 12/31/02 12/31/01 12/31/00 12/31/99 NET ASSET VALUE Beginning of period $ 19.95 $ 14.51 $ 20.08 $ 21.70 $ 15.93 $ 16.01 Investment activities Net investment income (loss) (0.06) (0.11) (0.11) (0.11) (0.03) (0.04) Net realized and unrealized gain (loss) 2.28 5.55 (5.46) (1.20) 8.28 1.22 Total from investment activities 2.22 5.44 (5.57) (1.31) 8.25 1.18 Distributions Net realized gain - - - (0.31) (2.48) (1.26) NET ASSET VALUE End of period $ 22.17 $ 19.95 $ 14.51 $ 20.08 $ 21.70 $ 15.93 --------------------------------------------------------------- Ratios/Supplemental Data Total return^ 11.13% 37.49% (27.74)% (5.97)% 52.19% 7.97% Ratio of total expenses to average net assets 0.92%! 1.00% 1.04% 1.02% 0.98% 1.11% Ratio of net investment income (loss) to average net assets (0.57)%! (0.64)% (0.64)% (0.60)% (0.22)% (0.25)% Portfolio turnover rate 36.7%! 44.8% 62.7% 74.6% 110.6% 81.9% Net assets, end of period (in millions) $ 1,310 $ 1,027 $ 678 $ 961 $ 972 $ 303 ^ Total return reflects the rate that an investor would have earned on an investment in the fund during each period, assuming reinvestment of all distributions. ! Annualized The accompanying notes are an integral part of these financial statements. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report (Unaudited) June 30, 2004 Portfolio of Investments (1) Shares/$ Par Value - -------------------------------------------------------------------------------- (Cost and value in $ 000s) COMMON STOCKS AND WARRANTS 97.8% BIOTECHNOLOGY 39.7% Other Biotechnology 6.4% Alexion Pharmaceutical *^ 200,000 3,720 Amylin Pharmaceuticals * 235,000 5,358 BioCryst Pharmaceuticals * 525,000 3,622 Cubist Pharmaceuticals * 925,000 10,267 Cytogen * 250,000 3,975 deCODE GENETICS * 450,000 3,825 Diversa * 300,000 3,039 Encysive Pharmaceuticals * 325,000 2,763 Exelixis * 750,000 7,567 Insmed, Warrants, 5/31/05 *!!@ 250,048 0 Inspire Phamaceuticals * 200,000 3,344 Keryx Biopharmaceuticals * 250,000 3,165 Ligand Pharmaceuticals, Class B * 75,000 1,304 Myriad Genetics * 350,000 5,222 Nektar Therapeutics * 200,000 3,992 NeoRx * 175,000 438 NeoRx, Warrants, 12/31/08 *!!@ 18,000 0 ONYX Pharmaceuticals * 420,000 17,791 Rigel Pharmaceuticals * 150,000 2,132 ViroLogic * 125,000 306 ViroPharma * 200,000 358 XOMA * 450,000 2,016 84,204 Major Biotechnology 33.3% Abgenix * 625,000 7,325 Alkermes * 1,100,000 14,960 Amgen *^ 757,500 41,337 Atherogenics * 70,000 1,332 Biogen Idec * 480,000 30,360 Celgene *^ 190,000 10,879 Cephalon * 765,000 41,310 CV Therapeutics *^ 200,000 3,352 Eyetech Pharmaceuticals * 60,000 2,575 Genentech *^ 425,000 23,885 Gilead Sciences *^ 900,000 60,300 Human Genome Sciences * 400,000 4,652 ICOS * 100,000 2,984 ImClone Systems *^ 885,000 75,924 Martek Biosciences * 75,000 4,213 Medicines Company * 663,500 20,243 MedImmune * 450,000 10,530 Millennium Pharmaceuticals * 200,000 2,760 Nabi * 80,000 1,138 Neurocrine Biosciences *^ 300,000 15,555 NPS Pharmaceuticals *^ 465,000 9,765 OSI Pharmaceuticals *^ 150,000 10,566 Protein Design Labs *^ 500,000 9,565 Seattle Genetics, Warrants, 12/31/11 *!!@ 50,000 0 Sepracor *^ 260,000 13,754 Transkaryotic Therapies * 100,000 1,496 Trimeris * 516,000 7,446 United Therapeutics * 100,000 2,565 Vertex Pharmaceuticals * 475,000 5,149 435,920 Total Biotechnology 520,124 LIFE SCIENCES 5.2% Life Sciences 5.2% Fisher Scientific * 320,000 18,480 Gen-Probe * 125,000 5,915 Invitrogen * 345,000 24,837 Molecular Devices * 110,000 1,956 Serologicals * 65,000 1,299 Symyx Technologies * 450,000 10,854 Waters Corporation * 100,000 4,778 Total Life Sciences 68,119 PHARMACEUTICALS 18.8% Major- Pharmaceutical 18.8% Able Laboratories * 391,000 8,039 Alcon 48,700 3,830 Allergan 55,000 4,924 Andrx * 50,000 1,396 Barr Pharmaceuticals * 25,000 843 Biocon 144A (INR) * 82,800 904 Elan ADR *^ 425,000 10,514 Eli Lilly ^ 235,000 16,429 Forest Laboratories *^ 300,000 16,989 Indevus Pharmaceuticals * 200,000 1,230 IVAX * 425,000 10,196 Johnson & Johnson 225,000 12,532 Medicis Pharmaceutical, Class A 25,000 999 Merck 52,500 2,494 MGI Pharma *^ 750,000 20,257 Novartis ADR 25,000 1,113 Noven Pharmaceuticals * 50,000 1,101 Novo Nordisk, Series B (DKK) 25,000 1,289 Penwest Pharmaceuticals * 100,000 1,281 Pfizer ^ 1,202,100 41,208 Roche Holding (CHF) 14,000 1,387 Salix Pharmaceuticals * 85,000 2,801 Sanofi-Synthelabo (EUR) 100,000 6,346 Schering-Plough 285,000 5,267 Shire Pharmaceuticals ADR * 95,000 2,540 Taro Pharmaceuticals, Class A *^ 150,000 6,525 Teva Pharmaceutical ADR 250,000 16,822 Valeant Pharmaceuticals International 401,700 8,034 Watson Pharmaceuticals * 225,000 6,052 Wyeth ^ 700,000 25,312 Yamanouchi Pharmaceutical (JPY) 225,000 7,552 Total Pharmaceuticals 246,206 PRODUCTS & DEVICES 10.8% Implants 10.8% Angiotech Pharmaceuticals * 300,000 6,045 Aspect Medical Systems * 425,000 7,850 Biomet 150,000 6,666 BioSphere Medical * 550,000 1,760 Boston Scientific *^ 400,000 17,120 C. R. Bard 175,000 9,914 Edwards Lifesciences * 120,000 4,182 Endologix * 375,000 1,834 EPIX Medical * 120,000 2,532 Fischer Imaging *! 590,000 1,357 Guidant 195,000 10,897 Haemonetics * 150,000 4,447 Integra LifeServices Holdings * 75,000 2,645 Kinetic Concepts * 255,000 12,724 Medtronic ^ 150,000 7,308 Regeneration Technologies * 275,000 2,951 St. Jude Medical * 180,000 13,617 STAAR * 375,000 2,925 Stryker 200,000 11,000 Synthes (CHF) 30,000 3,421 Wilson Greatbatch Technologies * 231,000 6,456 Zimmer Holdings * 50,000 4,410 Total Products & Devices 142,061 SERVICES 20.3% Distribution 5.2% AmerisourceBergen ^ 160,000 9,565 Cardinal Health ^ 100,000 7,005 Caremark RX * 575,000 18,940 Henry Schein * 25,000 1,579 NeighborCare * 200,000 6,266 Omnicare ^ 575,000 24,616 67,971 Information 0.2% WebMD * 280,000 2,610 2,610 Other Services 1.1% LabOne * 150,000 4,767 Laboratory Corporation of America * 25,000 992 Quest Diagnostics 100,000 8,495 14,254 Payors 10.1% Anthem *^ 725,000 64,931 UnitedHealth Group ^ 1,000,000 62,250 WellPoint Health Networks * 50,000 5,600 132,781 Providers 3.7% Community Health System * 225,000 6,023 HCA 300,000 12,477 Mariner Health Care * 480,000 12,924 Sunrise Senior Living * 175,000 6,850 Triad Hospitals * 50,000 1,862 Universal Health Services 25,000 1,147 Vencor 275,000 6,421 47,704 Total Services 265,320 Total Miscellaneous Common Stocks 3.0% 38,842 Total Common Stocks and Warrants (Cost $1,004,030) 1,280,672 CONVERTIBLE PREFERRED STOCKS 0.4% Control Delivery Systems, 8.00%, Series A *!!@ 37,216 1,000 Corus Pharma, 8.00%, Series C *!!@ 1,742,138 1,944 NeoRx, Series B *!!@ 45 225 Seattle Genetics, Series A *!!@ 40,000 2,390 Total Convertible Preferred Stocks (Cost $5,450) 5,559 PREFERRED STOCKS 0.2% Theravance, Series D1 !!@ 264,454 2,380 Total Preferred Stocks (Cost $2,380) 2,380 CORPORATE BONDS 0.8% Morgan Stanley, 144A, 6.00%, 6/1/05 250,000 10,713 Total Corporate Bonds (Cost $10,728) 10,713 OPTIONS PURCHASED 0.0% Taro Pharmaceuticals, Put, 7/17/04 @ $45.00 * 37,800 110 Total Options Purchased (Cost $53) 110 OPTIONS WRITTEN (1.7%) Alexion Pharmaceuticals, Call, 11/20/04 @ $25.00 * (125,000) (119) Alkermes, Put, 2/19/05 @ $15.00 * (25,000) (84) Amerisourcebergen, Call, 11/20/04 @ $65.00 * (50,000) (63) Amgen Call 1/22/05 @ $60.00 * (100,000) (177) 10/16/04 @ $60.00 * (25,000) (19) Put 1/22/05 @ $60.00 * (35,000) (234) 10/16/04 @ $60.00 * (30,000) (179) 7/17/04 @ $60.00 * (22,500) (122) Amylin Pharmaceuticals, Put, 1/22/05 @ $22.50 * (45,000) (134) Andrx, Put, 1/22/05 @ $30.00 * (60,000) (267) Angiotech Pharmaceuticals, Put, 9/15/04 @ $25.00 * (55,000) (283) Anthem Call, 9/18/04 @ $100.00 * (50,000) (39) Put 1/22/05 @ $90.00 * (50,000) (337) 9/18/04 @ $90.00 * (60,000) (255) Becton Dickinson, Put, 9/18/04 @ $55.00 * (50,000) (198) Biomet, Put, 1/22/05 @ $50.00 * (20,000) (131) Boston Scientific Call, 11/20/04 @ $45.00 * (100,000) (250) Put, 1/22/05 @ $45.00 * (50,000) (245) Cardinal Health, Call, 9/18/04 @ $70.00 * (75,000) (219) Caremark Rx, Put, 1/22/05 @ $40.00 * (50,000) (372) Celgene Put 1/22/05 @ $45.00 * (50,000) (117) 1/22/05 @ $50.00 * (35,000) (131) Cephalon Call, 1/22/05 @ $70.00 * (100,000) (60) Put, 11/20/04 @ $50.00 * (20,000) (44) CV Therapeutics, Call, 7/17/04 @ $17.50 * (25,300) (4) Dade Behring, Call, 8/21/04 @ $50.00 * (75,000) (111) Elan Call, 10/16/04 @ $30.00 * (100,000) (103) Put 1/21/06 @ $25.00 * (35,000) (199) 1/22/05 @ $25.00 * (40,000) (156) Eli Lilly, Call, 10/16/04 @ $80.00 * (100,000) (55) Fisher Scientific, Put, 9/18/04 @ $55.00 * (50,000) (113) Forest Laboratories Call, 1/22/05 @ $70.00 * (50,000) (55) Put, 1/22/05 @ $55.00 * (30,000) (122) Genentech Call, 9/18/04 @ $60.00 * (75,000) (126) Put, 1/22/05 @ $62.50 * (60,000) (534) Gilead Sciences Call 11/20/04 @ $70.00 * (100,000) (455) 8/21/04 @ $70.00 * (75,000) (174) Guidant Put 1/22/05 @ $55.00 * (35,000) (158) 1/22/05 @ $60.00 * (25,000) (180) HCA, Put, 1/22/05 @ $40.00 * (40,000) (90) ImClone Systems Call 1/22/05 @ $100.00 * (75,000) (465) 1/22/05 @ $95.00 * (25,000) (194) 11/20/04 @ $75.00 * (100,000) (1,585) 11/20/04 @ $90.00 * (100,000) (775) 7/17/04 @ $85.00 * (150,000) (435) 8/21/04 @ $45.00 * (50,000) (2,040) 8/21/04 @ $80.00 * (75,000) (690) 8/21/04 @ $85.00 * (200,000) (1,250) Put 1/22/05 @ $55.00 * (30,000) (46) 1/22/05 @ $60.00 * (40,000) (91) 11/20/04 @ $65.00 * (40,000) (86) 11/20/04 @ $70.00 * (25,000) (81) 11/20/04 @ $75.00 * (10,000) (46) 8/21/04 @ $70.00 * (25,000) (26) Invitrogen, Put, 1/22/05 @ $70.00 * (45,000) (268) King Pharmaceuticals, Put, 1/22/05 @ $25.00 * (23,200) (314) Medicines, Put, 10/16/04 @ $35.00 * (20,000) (118) Medtronic Call, 8/21/04 @ $47.50 * (75,000) (163) Put, 1/22/05 @ $50.00 * (15,000) (53) Merck, Put, 1/22/05 @ $55.00 * (25,000) (205) MGI Pharma Call 1/22/05 @ $32.50 * (150,000) (274) 8/21/04 @ $30.00 * (33,500) (28) 8/21/04 @ $35.00 * (50,000) (6) Put, 1/22/05 @ $32.50 * (120,000) (846) Nektar Therapeutics Put 11/20/04 @ $25.00 * (35,000) (229) 8/21/04 @ $22.50 * (30,000) (105) 8/21/04 @ $25.00 * (30,000) (167) Neurocrine Biosciences Call 11/20/04 @ $60.00 * (100,000) (237) 11/20/04 @ $65.00 * (75,000) (105) 2/19/05 @ $65.00 * (75,000) (165) 8/21/04 @ $60.00 * (50,000) (35) NPS Pharmaceuticals Call 11/20/04 @ $35.00 * (100,000) (20) 8/21/04 @ $25.00 * (75,000) (24) Omnicare, Call, 12/18/04 @ $45.00 * (12,500) (26) ONYX Pharmaceuticals Call 1/22/05 @ $60.00 * (50,000) (86) 7/17/04 @ $45.00 * (17,500) (7) 8/21/04 @ $45.00 * (100,000) (160) 8/21/04 @ $50.00 * (17,500) (10) OSI Pharmaceuticals Call 1/22/05 @ $90.00 * (50,000) (233) 10/16/04 @ $90.00 * (75,000) (159) Put, 1/22/05 @ $80.00 * (55,000) (885) Pfizer Call 1/22/05 @ $37.50 * (150,000) (112) 9/18/04 @ $37.50 * (100,000) (23) Put, 1/22/05 @ $37.50 * (60,000) (240) Protein Design Labs Call, 8/21/04 @ $22.50 * (50,000) (16) Put, 8/21/04 @ $22.50 * (30,000) (111) Sepracor Call 10/16/04 @ $60.00 * (75,000) (167) 7/17/04 @ $55.00 * (75,000) (101) Put 1/21/06 @ $55.00 * (25,000) (243) 1/22/05 @ $50.00 * (55,000) (267) 1/22/05 @ $55.00 * (75,000) (547) St. Jude Medical Put 1/22/05 @ $75.00 * (20,000) (114) 10/16/04 @ $70.00 * (25,000) (59) Taro Pharmaceuticals Call 10/16/04 @ $45.00 * (50,000) (173) 10/16/04 @ $50.00 * (100,000) (172) Teva Pharmaceutical, Put, 12/18/04 @ $70.00 * (15,000) (82) Triad Hospitals, Put, 1/22/05 @ $40.00 * (25,000) (115) Trimeris, Call, 7/17/04 @ $15.00 * (75,000) (15) Unitedhealth Group Call, 9/18/04 @ $70.00 * (25,000) (9) Put, 9/18/04 @ $65.00 * (25,000) (104) Waters Corporation, Put, 11/20/04 @ $40.00 * (25,000) (11) Wyeth Call 1/22/05 @ $40.00 * (200,000) (215) 10/16/04 @ $40.00 * (100,000) (45) Put, 1/22/05 @ $35.00 * (20,000) (43) Total Options Written (Cost $(22,075)) (22,436) SHORT-TERM INVESTMENTS 2.9% Money Market Fund 2.9% T. Rowe Price Reserve Investment Fund, 1.16% # 37,741,196 37,741 Total Short-Term Investments (Cost $37,741) 37,741 Total Investments in Securities 100.4% of Net Assets (Cost $1,038,307) $1,314,739 ---------- (1) Denominated in U.S. dollar unless otherwise noted # Seven-day yield * Non-income producing ^ All or a portion of this security is pledged to cover written call options at June 30, 2004. ! Affiliated company - See Note 2. !! Security contains restrictions as to public resale pursuant to the Securities Act of 1933 and related rules - total value of such securities at period-end amounts to $7,939 and represents 0.7% of net assets @ Valued by the T. Rowe Price Valuation Committee, established by the fund's Board of Directors 144A Security was purchased pursuant to Rule 144A under the Securities Act of 1933 and may be resold in transactions exempt from registration only to qualified institutional buyers - total value of such securities at period-end amounts to $11,617 and represents 0.9% of net assets ADR American Depository Receipts CHF Swiss franc DKK Danish krone EUR Euro INR Indian rupee JPY Japanese yen The accompanying notes are an integral part of these financial statements. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report (Unaudited) June 30, 2004 STATEMENT OF ASSETS AND LIABILITIES - -------------------------------------------------------------------------------- (In thousands except shares and per share amounts) Assets Investments in securities, at value (cost $1,038,307) $ 1,314,739 Other assets 2,252 Total assets 1,316,991 Liabilities Total liabilities 6,966 NET ASSETS $ 1,310,025 ------------- Net Assets Consist of: Undistributed net investment income (loss) $ (3,372) Undistributed net realized gain (loss) (40,047) Net unrealized gain (loss) 276,432 Paid-in-capital applicable to 59,079,646 shares of $0.0001 par value capital stock outstanding; 1,000,000,000 shares authorized 1,077,012 NET ASSETS $ 1,310,025 ------------- NET ASSET VALUE PER SHARE $ 22.17 ------------- The accompanying notes are an integral part of these financial statements. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report (Unaudited) STATEMENT OF OPERATIONS - -------------------------------------------------------------------------------- ($ 000s) 6 Months Ended 6/30/04 Investment Income (Loss) Income Dividend $ 2,093 Interest 1 Total income 2,094 Expenses Investment management 3,939 Shareholder servicing 1,309 Custody and accounting 105 Prospectus and shareholder reports 67 Registration 25 Legal and audit 16 Directors 4 Miscellaneous 1 Total expenses 5,466 Net investment income (loss) (3,372) Realized and Unrealized Gain (Loss) Net realized gain (loss) Securities 35,661 Written options 11,532 Foreign currency transactions (44) Net realized gain (loss) 47,149 Change in net unrealized gain (loss) Securities 77,444 Written options (4,759) Other assets and liabilities denominated in foreign currencies (1) Change in net unrealized gain (loss) 72,684 Net realized and unrealized gain (loss) 119,833 INCREASE (DECREASE) IN NET ASSETS FROM OPERATIONS $ 116,461 ------------- The accompanying notes are an integral part of these financial statements. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report (Unaudited) STATEMENT OF CHANGES IN NET ASSETS - -------------------------------------------------------------------------------- ($ 000s) 6 Months Year Ended Ended 6/30/04 12/31/03 Increase (Decrease) in Net Assets Operations Net investment income (loss) $ (3,372) $ (5,438) Net realized gain (loss) 47,149 3,119 Change in net unrealized gain (loss) 72,684 266,737 Increase (decrease) in net assets from operations 116,461 264,418 Capital share transactions * Shares sold 260,790 238,878 Shares redeemed (94,593) (153,885) Increase (decrease) in net assets from capital share transactions 166,197 84,993 Net Assets Increase (decrease) during period 282,658 349,411 Beginning of period 1,027,367 677,956 End of period $ 1,310,025 $ 1,027,367 ----------- ----------- (Including undistributed net investment income (loss) of $(3,372) at 6/30/04 and $0 at 12/31/03) *Share information Shares sold 11,981 13,705 Shares redeemed (4,398) (8,931) Increase (decrease) in shares outstanding 7,583 4,774 The accompanying notes are an integral part of these financial statements. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report (Unaudited) June 30, 2004 NOTES TO FINANCIAL STATEMENTS - -------------------------------------------------------------------------------- NOTE 1 - SIGNIFICANT ACCOUNTING POLICIES T. Rowe Price Health Sciences Fund, Inc. (the fund) is registered under the Investment Company Act of 1940 (the 1940 Act) as a diversified, open-end management investment company and commenced operations on December 29, 1995. The fund seeks long-term capital appreciation. The accompanying financial statements were prepared in accordance with accounting principles generally accepted in the United States of America, which require the use of estimates made by fund management. Valuation The fund values its investments and computes its net asset value per share at the close of the New York Stock Exchange (NYSE), normally 4 p.m. ET, each day that the NYSE is open for business. Equity securities listed or regularly traded on a securities exchange or in the over-the-counter market are valued at the last quoted sale price or, for certain markets, the official closing price at the time the valuations are made, except for OTC Bulletin Board securities, which are valued at the mean of the latest bid and asked prices. A security that is listed or traded on more than one exchange is valued at the quotation on the exchange determined to be the primary market for such security. Listed securities not traded on a particular day are valued at the mean of the latest bid and asked prices for domestic securities and the last quoted sale price for international securities. Debt securities are generally traded in the over-the-counter market. Securities with original maturities of one year or more are valued at prices furnished by dealers who make markets in such securities or by an independent pricing service, which considers yield or price of bonds of comparable quality, coupon, maturity, and type, as well as prices quoted by dealers who make markets in such securities. Securities with original maturities of less than one year are valued at amortized cost in local currency, which approximates fair value when combined with accrued interest. Investments in mutual funds are valued at the mutual fund's closing net asset value per share on the day of valuation. Purchased and written options are valued at the mean of the closing bid and asked prices. Other investments and those for which the above valuation procedures are inappropriate or are deemed not to reflect fair value are stated at fair value as determined in good faith by the T. Rowe Price Valuation Committee, established by the fund's Board of Directors. Most foreign markets close before the close of trading on the NYSE. If the fund determines that developments between the close of a foreign market and the close of the NYSE will, in its judgment, materially affect the value of some or all of its portfolio securities, which in turn will affect the fund's share price, the fund will adjust the previous closing prices to reflect the fair value of the securities as of the close of the NYSE, as determined in good faith by the T. Rowe Price Valuation Committee, established by the fund's Board of Directors. A fund may also fair value securities in other situations, such as when a particular foreign market is closed but the fund is open. In deciding whether to make fair value adjustments, the fund reviews a variety of factors, including developments in foreign markets, the performance of U.S. securities markets, and the performance of instruments trading in U.S. markets that represent foreign securities and baskets of foreign securities. The fund uses outside pricing services to provide it with closing market prices and information used for adjusting those prices. The fund cannot predict how often it will use closing prices and how often it will adjust those prices. As a means of evaluating its fair value process, the fund routinely compares closing market prices, the next day's opening prices in the same markets, and adjusted prices. Currency Translation Assets, including investments, and liabilities denominated in foreign currencies are translated into U.S. dollar values each day at the prevailing exchange rate, using the mean of the bid and asked prices of such currencies against U.S. dollars as quoted by a major bank. Purchases and sales of securities, income, and expenses are translated into U.S. dollars at the prevailing exchange rate on the date of the transaction. The effect of changes in foreign currency exchange rates on realized and unrealized security gains and losses is reflected as a component of security gains and losses. Rebates and Credits Subject to best execution, the fund may direct certain security trades to brokers who have agreed to rebate a portion of the related brokerage commission to the fund in cash. Commission rebates are included in realized gain on securities in the accompanying financial statements and totaled $43,000 for the six months ended June 30, 2004. Additionally, the fund earns credits on temporarily uninvested cash balances at the custodian that reduce the fund's custody charges. Custody expense in the accompanying financial statements is presented before reduction for credits. Investment Transactions, Investment Income, and Distributions Income and expenses are recorded on the accrual basis. Premiums and discounts on debt securities are amortized for financial reporting purposes. Dividends received from mutual fund investments are reflected as dividend income; capital gain distributions are reflected as realized gain/loss. Dividend income and capital gain distributions are recorded on the ex-dividend date. Investment transactions are accounted for on the trade date. Realized gains and losses are reported on the identified cost basis. Distributions to shareholders are recorded on the ex-dividend date. Income distributions are declared and paid on an annual basis. Capital gain distributions, if any, are declared and paid by the fund, typically on an annual basis. Other In the normal course of business, the fund enters into contracts that provide general indemnifications. The fund's maximum exposure under these arrangements is dependent on claims that may be made against the fund in the future and, therefore, cannot be estimated; however, based on experience, the risk of material loss from such claims is considered remote. NOTE 2 - INVESTMENT TRANSACTIONS Consistent with its investment objective, the fund engages in the following practices to manage exposure to certain risks or enhance performance. The investment objective, policies, program, and risk factors of the fund are described more fully in the fund's prospectus and Statement of Additional Information. Options Call and put options give the holder the right to purchase or sell, respectively, a security at a specified price on a certain date. Risks arise from possible illiquidity of the options market and from movements in security values. Options are reflected in the accompanying Portfolio of Investments at market value. Transactions in options written and related premiums received during the six months ended June 30, 2004, were as follows: - -------------------------------------------------------------------------------- Number of Contracts Premiums Outstanding at beginning of period 55,000 $ 16,641,000 Written 115,000 39,443,000 Exercised (2,000) (614,000) Expired (12,000) (1,894,000) Closed (96,000) (31,501,000) Outstanding at end of period 60,000 $ 22,075,000 ------ ------------ Affiliated Companies The fund may invest in certain securities that are considered affiliated companies. As defined by the 1940 Act, an affiliated company is one in which the fund owns 5% or more of the outstanding voting securities. At June 30, 2004, the value of affiliated companies totaled $1,357,000, representing 0.1% of the value of the fund's investments in securities. Other Purchases and sales of portfolio securities, other than short-term securities, aggregated $380,755,000 and $216,501,000, respectively, for the six months ended June 30, 2004. NOTE 3 - FEDERAL INCOME TAXES No provision for federal income taxes is required since the fund intends to continue to qualify as a regulated investment company under Subchapter M of the Internal Revenue Code and distribute to shareholders all of its taxable income and gains. Federal income tax regulations differ from generally accepted accounting principles; therefore, distributions determined in accordance with tax regulations may differ in amount or character from net investment income and realized gains for financial reporting purposes. Financial reporting records are adjusted for permanent book/tax differences to reflect tax character. Financial records are not adjusted for temporary differences. The amount and character of tax-basis distributions and composition of net assets are finalized at fiscal year-end; accordingly, tax-basis balances have not been determined as of June 30, 2004. The fund intends to retain realized gains to the extent of available capital loss carryforwards. As of December 31, 2003, the fund had $86,373,000 of unused capital loss carryforwards, of which $9,998,000 expire in 2009, $65,226,000 expire in 2010, and $11,149,000 expire in 2011. At June 30, 2004, the cost of investments for federal income tax purposes was $1,038,307,000. Net unrealized gain aggregated $276,432,000 at period-end, of which $359,604,000 related to appreciated investments and $83,172,000 related to depreciated investments. NOTE 4 - RELATED PARTY TRANSACTIONS The fund is managed by T. Rowe Price Associates, Inc. (the manager or Price Associates), a wholly owned subsidiary of T. Rowe Price Group, Inc. The investment management agreement between the fund and the manager provides for an annual investment management fee, which is computed daily and paid monthly. The fee consists of an individual fund fee, equal to 0.35 % of the fund's average daily net assets, and the fund's pro-rata share of a group fee. The group fee is calculated based on the combined net assets of certain mutual funds sponsored by Price Associates (the group) applied to a graduated fee schedule, with rates ranging from 0.48% for the first $1 billion of assets to 0.295% for assets in excess of $120 billion. The fund's portion of the group fee is determined by the ratio of its average daily net assets to those of the group. At June 30, 2004, the effective annual group fee rate was 0.31%, and investment management fee payable totaled $701,000. In addition, the fund has entered into service agreements with Price Associates and two wholly owned subsidiaries of Price Associates (collectively, Price). Price Associates computes the daily share price and maintains the financial records of the fund. T. Rowe Price Services, Inc., provides shareholder and administrative services in its capacity as the fund's transfer and dividend disbursing agent. T. Rowe Price Retirement Plan Services, Inc., provides subaccounting and recordkeeping services for certain retirement accounts invested in the fund. Expenses incurred pursuant to these service agreements totaled $898,000 for the six months ended June 30, 2004, of which $165,000 was payable at period-end. Additionally, the fund is one of several mutual funds in which certain college savings plans managed by Price Associates may invest. As approved by the fund's Board of Directors, shareholder servicing costs associated with each college savings plan are borne by the fund in proportion to the average daily value of its shares owned by the college savings plan. For the six months ended June 30, 2004, the fund was charged $20,000 for shareholder servicing costs related to the college savings plans, of which $15,000 was for services provided by Price. At June 30, 2004, approximately 0.8% of the outstanding shares of the fund were held by college savings plans. The fund may invest in the T. Rowe Price Reserve Investment Fund and the T. Rowe Price Government Reserve Investment Fund (collectively, the Reserve Funds), open-end management investment companies managed by Price Associates. The Reserve Funds are offered as cash management options to mutual funds, trusts, and other accounts managed by Price Associates and/or its affiliates, and are not available for direct purchase by members of the public. The Reserve Funds pay no investment management fees. During the six months ended June 30, 2004, dividend income from the Reserve Funds totaled $165,000. T. Rowe Price Health Sciences Fund - -------------------------------------------------------------------------------- Certified Semiannual Report Information on Proxy Voting - -------------------------------------------------------------------------------- A description of the policies and procedures that the T. Rowe Price Health Sciences Fund uses to determine how to vote proxies relating to portfolio securities is available, without charge, upon request by calling 1-800-225-5132. It also appears in the fund's Statement of Additional Information (Form 485B), which can be found on the SEC's Web site, www.sec.gov. Item 2. Code of Ethics. A code of ethics, as defined in Item 2 of Form N-CSR, applicable to its principal executive officer, principal financial officer, principal accounting officer or controller, or persons performing similar functions is filed as an exhibit to the registrant's annual Form N-CSR. No substantive amendments were approved or waivers were granted to this code of ethics during the registrant's most recent fiscal half-year. Item 3. Audit Committee Financial Expert. Disclosure required in registrant's annual Form N-CSR. Item 4. Principal Accountant Fees and Services. Disclosure required in registrant's annual Form N-CSR. Item 5. Audit Committee of Listed Registrants. Not applicable. Item 6. Schedule of Investments. Not applicable. The complete schedule of investments is included in Item 1 of this Form N-CSR. Item 7. Disclosure of Proxy Voting Policies and Procedures for Closed-End Management Investment Companies. Not applicable. Item 8. Purchases of Equity Securities by Closed-End Management Investment Company and Affiliated Purchasers. Not applicable. Item 9. Submission of Matters to a Vote of Security Holders. Not applicable. Item 10. Controls and Procedures. (a) The registrant's principal executive officer and principal financial officer have evaluated the registrant's disclosure controls and procedures within 90 days of this filing and have concluded that the registrant's disclosure controls and procedures were effective, as of that date, in ensuring that information required to be disclosed by the registrant in this Form N-CSR was recorded, processed, summarized, and reported timely. (b) The registrant's principal executive officer and principal financial officer are aware of no changes in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal half-year that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting. Item 11. Exhibits. (a)(1) The registrant's code of ethics pursuant to Item 2 of Form N-CSR is filed with the registrant's annual Form N-CSR. (2) Separate certifications by the registrant's principal executive officer and principal financial officer, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 and required by Rule 30a-2(a) under the Investment Company Act of 1940, are attached. (3) Written solicitation to repurchase securities issued by closed-end companies: not applicable. (b) A certification by the registrant's principal executive officer and principal financial officer, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and required by Rule 30a-2(b) under the Investment Company Act of 1940, is attached. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. T. Rowe Price Health Sciences Fund, Inc. By: /s/ James S. Riepe James S. Riepe Principal Executive Officer Date: August 16, 2004 Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated. By: /s/ James S. Riepe James S. Riepe Principal Executive Officer Date: August 16, 2004 By: /s/ Joseph A. Carrier Joseph A. Carrier Principal Financial Officer Date: August 16, 2004