As filed with the Securities and Exchange Commission on April __, 2001

                                                   Registration No. 333-______

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-1

                          Registration Statement Under
                           THE SECURITIES ACT OF 1933

                               CEL-SCI CORPORATION
                           ---- --------------------
                (Exact name of registrant as specified in charter

       Delaware                        2831                 52-2278236
       --------                  ---------------            ----------
(State or other jurisdiction  (Primary Standard Classi-    (IRS Employer
of incorporation)              fication Code Number)        I.D. Number)

                              8229 Boone Blvd. #802
                             Vienna, Virginia 22182
                                 (703) 506-9460
                          ------------ ---------------
          (Address and telephone number of principal executive offices)

                                  Geert Kersten
                              8229 Boone Blvd. #802
                             Vienna, Virginia 22182
                                 (703) 506-9460
                             ----- ---------------
            (Name, address and telephone number of agent for service)

         Copies of all communications, including all communications sent
                  to the agent for service, should be sent to:

                              William T. Hart, Esq.
                               Hart & Trinen, LLP
                             1624 Washington Street
                             Denver, Colorado 80203
                                  303-839-0061

        APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:
 As soon as practicable after the effective date of this Registration Statement





     If any of the securities being registered on this Form are to be offered on
a delayed or continuous  basis  pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box [X].

     If this Form is filed to  register  additional  securities  for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. [ ]

      If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. [ ]

      If this Form is a post-effective amendment filed pursuant to Rule 462(d)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. [ ]

                        CALCULATION OF REGISTRATION FEE
==============================================================================

Title of each                        Proposed      Proposed
 Class of                            Maximum       Maximum
Securities            Securities     Offering      Aggregate      Amount of
   to be                  to be      Price Per     Offering      Registration
Registered            Registered      Share (3)     Price            Fee
- ----------            ----------     -----------   ---------     ------------

Common stock (1)    2,800,000          $1.37      $3,836,000        $1,013
Common stock (2)      200,800          $1.37        $275,096            73

Total                                                               $1,086
- --------------------------------------------------------------------------------

(1)  Represents  shares  issuable to Paul Revere  Capital  Partners,  Ltd. under
     equity line of credit.
(2)  Represents  shares  issuable  upon the  exercise of  warrants  held by Paul
     Revere Capital Partners.
(3)  Offering price computed in accordance with Rule 457(c).

     Pursuant  to  Rule  416,   this   Registration   Statement   includes  such
indeterminate  number of  additional  securities as may be required for issuance
upon the  exercise of the options or warrants as a result of any  adjustment  in
the number of securities issuable by reason of the options or warrants.

     The registrant  hereby amends this  Registration  Statement on such date or
dates as may be necessary to delay its effective date until the registrant shall
file a further  amendment  which  specifically  states  that  this  Registration
Statement shall  thereafter  become effective in accordance with Section 8(a) of
the  Securities  Act of l933 or until the  Registration  Statement  shall become
effective on such date as the Commission,  acting pursuant to said Section 8(a),
may determine.





PROSPECTUS

                               CEL-SCI CORPORATION

                                  Common Stock

     This  prospectus  may be used only in  connection  with sales of the common
stock of CEL-SCI  Corporation by Paul Revere Capital Partners,  Ltd. Paul Revere
Capital  Partners will sell shares of common stock  purchased from CEL-SCI under
an equity line of credit  agreement and up to _____ shares of common stock which
may be issued upon the  exercise of warrants.  The warrants  were issued to Paul
Revere Capital Partners upon the signing of the equity line of credit agreement.

     CEL-SCI will not receive any proceeds  from the sale of the common stock by
the selling stockholders. CEL-SCI will pay for the expenses of this offering.

      CEL-SCI's common stock is quoted on the American Stock Exchange under the
symbol "CVM." On April 26, 2001 the closing price for one share of the CEL-SCI's
common stock was $1.37.

      Neither the Securities and Exchange Commission nor any state securities
commission has approved or disapproved of these securities or passed upon the
accuracy or adequacy of this prospectus. Any representation to the contrary is a
criminal offense.

      These securities are speculative and involve a high degree of risk. For a
description of certain important factors that should be considered by
prospective investors, see "Risk Factors" beginning on page ____ of this
Prospectus





                 The date of this prospectus is _________, 2001






                               PROSPECTUS SUMMARY

      THIS SUMMARY IS QUALIFIED IN ITS ENTIRETY BY THE MORE DETAILED INFORMATION
APPEARING ELSEWHERE IN THIS PROSPECTUS.

CEL-SCI

     CEL-SCI  Corporation was formed as a Colorado  corporation in 1983. CEL-SCI
is involved in the  research  and  development  of certain  drugs and  vaccines.
CEL-SCI  manufactures  MULTIKINE,  its first, and main product,  using CEL-SCI's
proprietary  cell  culture  technologies,   which  involve  a  combination,   or
"cocktail",   of  natural  human   interleukin-2  and  certain  lymphokines  and
cytokines.  CEL-SCI is testing  MULTIKINE  to  determine  if it is  effective in
improving the immune response of cancer patients.  Another technology CEL-SCI is
developing,  Ligand Epitope Antigen  Presentation  System  (LEAPS),  is a T-cell
modulation  technology  which CEL-SCI is testing to determine if it is effective
in developing  potential  treatments  and/or vaccines against various  diseases.
Present  target  diseases  are  AIDS,  herpes  simplex,  malaria,  tuberculosis,
prostate cancer and breast cancer.

     Before  human  testing  can  begin  with  respect  to a drug or  biological
product, preclinical studies are conducted in laboratory animals to evaluate the
potential efficacy and the safety of a product. Human clinical studies generally
involve  a  three-phase  process.  The  initial  clinical  evaluation,  Phase I,
consists of administering  the product and testing for safe and tolerable dosage
levels.  Phase II trials  continue the  evaluation  of safety and  determine the
appropriate dosage for the product,  identify possible side effects and risks in
a larger group of subjects,  and provide  preliminary  indications  of efficacy.
Phase III trials  consist of testing  for  actual  clinical  efficacy  within an
expanded group of patients at geographically dispersed test sites.

     CEL-SCI has funded the costs  associated  with the clinical trials relating
to CEL-SCI's  technologies,  research expenditures and CEL-SCI's  administrative
expenses with the public and private  sales of shares of CEL-SCI's  common stock
and borrowings from third parties, including affiliates of CEL-SCI.

     CEL-SCI does not expect to develop  commercial  products for several years,
if at  all.  CEL-SCI  has had  operating  losses  since  its  inception,  had an
accumulated  deficit of  approximately  $(63,650,000)  at December 31, 2000, and
expects to incur substantial losses for the foreseeable future.

     CEL-SCI's  executive offices are located at 8229 Boone Blvd., #802, Vienna,
Virginia 22182, and its telephone number is (703) 506-9460.






The Offering

     In order to provide a  possible  source of funding  for  CEL-SCI's  current
activities and for the development of its current and planned products,  CEL-SCI
has entered  into an equity line of credit  agreement  with Paul Revere  Capital
Partners.

     Under the equity line of credit agreement, Paul Revere Capital Partners has
agreed to provide  CEL-SCI with up to  $10,000,000  of funding during the twenty
four-month period following the effective date of the registration  statement to
which this prospectus relates. During this twenty four-month period, CEL-SCI may
request a  drawdown  under the equity  line of credit by  selling  shares of its
common stock to Paul Revere Capital  Partners,  and Paul Revere Capital Partners
will be obligated to purchase the shares.  The minimum  amount  CEL-SCI can draw
down at any one time is $100,000,  and the maximum  amount CEL-SCI can draw down
at any one time will be determined  at the time of the drawdown  request using a
formula contained in the equity line of credit agreement.  CEL-SCI may request a
drawdown once every 24 trading days,  although CEL-SCI is under no obligation to
request any drawdowns under the equity line of credit.

     During the 22 trading  days  following  a drawdown  request,  CEL-SCI  will
calculate the amount of shares it will sell to Paul Revere Capital  Partners and
the purchase price per share.  The purchase price per share of common stock will
be based on the daily volume  weighted  average price of CEL-SCI's  common stock
during each of the 22 trading days immediately following the drawdown date, less
a discount of 11%.

     Using the  formula  contained  in the equity line of credit  agreement,  if
CEL-SCI had requested a drawdown on April 12, 2001,  the maximum  amount CEL-SCI
could draw down during the  subsequent 22 trading days would have been $365,304.
Based upon the daily volume  weighted  average of CEL-SCI's  common stock during
these 22 trading  days,  CEL-SCI  would have sold  273,635  shares of its common
stock to Paul Revere Capital Partners and would have received  $365,304 from the
sale of these  shares.  For more  details on the maximum  drawdown  amount,  the
calculation  of the purchase  price and the number of shares  CEL-SCI will sell,
see "Equity Line of Credit Agreement" beginning on page 7 of this prospectus.

     CEL-SCI is  registering  the shares of common stock issuable to Paul Revere
Capital Partners under the equity line of credit,  as well as the 200,800 shares
underlying the warrants that CEL-SCI  granted to Paul Revere  Capital  Partners.
These  shares  may be  offered  for  sale  from  time to time by  means  of this
prospectus by or for the account of Paul Revere Capital  Partners.  CEL-SCI will
prepare  and  file  amendments  and  supplements  to this  prospectus  as may be
necessary  in order to keep this  prospectus  effective  as long as the  selling
shareholders  hold shares of CEL-SCI's common stock or until these shares can be
sold under an  appropriate  exemption from  registration.  CEL-SCI has agreed to
bear the  expenses of  registering  the shares,  including  Paul Revere  Capital
Partners's legal fees of $35,000,  but not the expenses  associated with selling
the shares, such as broker discounts and commissions.

     As of April 12, 2001,  CEL-SCI had 21,116,543 shares of common stock issued
and outstanding. The number of outstanding shares does not give effect to shares



which may be issued  pursuant to the  equity-line of credit or upon the exercise
and/or  conversion of options,  warrants or convertible  notes. See "Comparative
Share Data".

     CEL-SCI will not receive any  proceeds  from the sale of the shares by Paul
Revere Capital Partners. However, CEL-SCI will receive proceeds from any sale of
common  stock to Paul Revere  Capital  Partners  under the equity line of credit
agreement  and  upon  the  exercise  of  warrants  held by Paul  Revere  Capital
Partners,  when, and if, its pays the exercise price in cash. CEL-SCI expects to
use substantially all the net proceeds for general and administrative  expenses,
research and clinical trials.

     The purchase of the securities  offered by this prospectus  involves a high
degree of risk.  Risk factors  include the lack of revenues and history of loss,
and the need for  additional  capital.  See the "Risk  Factors"  section of this
prospectus for additional Risk Factors.

Summary Financial Data

     The financial data presented  below should be read in conjunction  with the
more  detailed  financial  statements  and  related  notes  which  are  included
elsewhere  in this  prospectus  along with the  section  entitled  "Management's
Discussion and Analysis of Financial Condition and Results of Operation."

Results of Operations:

                                     Year Ended        Three Months Ended
                                 September 30, 2000     December 31, 2000
                                 ------------------    ------------------

Investment Income and Other
  Revenues:                        $442,551               $249,808

Expenses:
Research and Development          4,978,714              2,017,007
Depreciation and Amortization       220,994                 49,079
General and Administrative        3,721,240                727,211
                                  ---------                -------

Net Loss                        $(8,478,397)           $(2,543,489)
                                ============           ============

Loss per common share
 (basic and diluted)                 $(0.44)                $(0.12)

Weighted average common
  Shares outstanding             19,259,190             20,459,913






Balance Sheet Data:

                                 September 30, 2000      December 31, 2000

Working Capital                   $11,725,940              $9,230,208
Total Assets                       13,808,882              11,263,832
Total Liabilities                     847,423                 789,854
Shareholders' Equity               12,961,459              10,473,978

Forward Looking Statements

     This prospectus contains various forward-looking  statements that are based
on CEL-SCI's  beliefs as well as assumptions  made by and information  currently
available  to  CEL-SCI.  When  used in this  prospectus,  the  words  "believe",
"expect",  "anticipate",  "estimate"  and similar  expressions  are  intended to
identify  forward-looking  statements.  Such  statements may include  statements
regarding seeking business opportunities, payment of operating expenses, and the
like,  and are subject to certain risks,  uncertainties  and  assumptions  which
could cause actual results to differ  materially from  projections or estimates.
Factors which could cause actual  results to differ  materially are discussed at
length under the heading "Risk  Factors".  Should one or more of the  enumerated
risks or  uncertainties  materialize,  or should  underlying  assumptions  prove
incorrect, actual results may vary materially from those anticipated,  estimated
or  projected.  Investors  should not place undue  reliance  on  forward-looking
statements, all of which speak only as of the date made.

                                  RISK FACTORS

     Investors  should  be aware  that this  offering  involves  certain  risks,
including those described below, which could adversely affect the value of their
holdings of common stock. CEL-SCI does not make, nor has it authorized any other
person to make,  any  representation  about the future market value of CEL-SCI's
common stock. In addition to the other information contained in this prospectus,
the following factors should be considered carefully in evaluating an investment
in the Shares offered by this prospectus

CEL-SCI Has Earned Only Limited Revenues and Has a History of Losses.
- --------------------------------------------------------------------

     CEL-SCI has had only limited  revenues  since it was formed in 1983.  Since
the date of its  formation  and through  December 31, 2000 CEL-SCI  incurred net
losses of  approximately  $(63,650,000).  During the years ended  September  30,
1998, 1999 and 2000 CEL-SCI  suffered losses of  $(6,442,683),  $(7,490,725) and
$(8,478,397)  respectively.  CEL-SCI has relied principally upon the proceeds of
public and private sales of securities to finance its activities to date. All of
CEL-SCI's  potential  products are in the early stages of  development,  and any
commercial sale of these products will be many years away. Accordingly,  CEL-SCI
expects to incur substantial losses for the foreseeable future.

     There can be no assurance CEL-SCI will be profitable.  At the present time,
CEL-SCI  intends  to  use  available  funds  to  finance  CEL-SCI's  operations.



Accordingly, while payment of dividends rests within the discretion of the Board
of Directors,  no common stock  dividends have been declared or paid by CEL-SCI.
CEL-SCI does not presently intend to pay dividends on its common stock and there
can be no assurance that common stock dividends will ever be paid.

If  Cel-Sci  cannot  obtain  additional  capital,  Cel-Sci  may have to delay or
postpone  development and research  expenditures  which may influence  Cel-Sci's
ability to produce a timely and competitive product.

     Clinical and other studies  necessary to obtain  approval of a new drug can
be time  consuming  and costly,  especially  in the United  States,  but also in
foreign countries.  The different steps necessary to obtain regulatory approval,
especially that of the Food and Drug  Administration,  involve significant costs
and may require  several  years to complete.  CEL-SCI  expects that it will need
additional  financing over an extended period of time in order to fund the costs
of future clinical  trials,  related  research,  and general and  administrative
expenses.  Although  the equity  line of credit  agreement  is  expected to be a
source of  funding,  the amounts  which  CEL-SCI is able to draw from the equity
line during each drawdown period may not satisfy CEL-SCI's capital needs.  There
can be no assurance  that CEL-SCI will be able to obtain the funding  needed for
its future operations

If Cost Estimates for Clinical Trials and Research Are Inaccurate, CEL-SCI Will
Require Additional Funding.

     CEL-SCI's estimates of the costs associated with future clinical trials and
research may be substantially  lower than the actual costs of these  activities.
If CEL-SCI's cost estimates are incorrect,  CEL-SCI will need additional funding
for its research efforts.

Any failure to obtain or any delay in obtaining  required  regulatory  approvals
may  adversely  affect  the  ability  of  CEL-SCI  or  potential   licensees  to
successfully market any products they may develop.

     Therapeutic agents,  drugs and diagnostic products are subject to approval,
prior to general  marketing,  by the FDA in the United  States and by comparable
agencies  in  most  foreign   countries.   The  process  of  obtaining  FDA  and
corresponding  foreign approvals is costly and time consuming,  particularly for
pharmaceutical  products  such as those which might  ultimately  be developed by
CEL-SCI, VTI or its licensees, and there can be no assurance that such approvals
will be granted.  Also, the extent of adverse government regulations which might
arise from future legislative or administrative action cannot be predicted.

CEL-SCI  has,  at the present  time,  only one source of  multikine  and if this
source  could not,  for any  reason,  supply  CEL-SCI  with  Multikine,  CEL-SCI
estimates that it would take  approximately six to ten months to obtain supplies
of Multikine under an alternative manufacturing arrangement.

     CEL-SCI has an agreement with an unrelated  corporation for the production,
until 2006,  of Multikine  for research and testing  purposes.  CEL-SCI does not
know what cost it would incur to obtain an alternative source of supply.




There can be no assurance  that  CEL-SCI will achieve or maintain a  competitive
position  or that  other  technological  developments  will not cause  CEL-SCI's
proprietary technologies to become uneconomical or obsolete.

     The biomedical  field in which CEL-SCI is involved is undergoing  rapid and
significant  technological  change.  The  successful  development of therapeutic
agents  from   CEL-SCI's   compounds,   compositions   and   processes   through
CEL-SCI-financed research or as a result of possible licensing arrangements with
pharmaceutical  or other  companies,  will  depend on its  ability  to be in the
technological forefront of this field.

     Many pharmaceutical and biotechnology companies are developing products for
the  prevention or treatment of cancer and  infectious  diseases.  Many of these
companies have substantial  financial,  research and development,  and marketing
resources and are capable of providing  significant long-term competition either
by establishing  in-house research groups or by forming  collaborative  ventures
with  other  entities.  In  addition,  both  smaller  companies  and  non-profit
institutions are active in research  relating to cancer and infectious  diseases
and are expected to become more active in the future.

CEL-SCI's Patents Might Not Protect CEL-SCI's Technology from Competitors.

     Certain aspects of CEL-SCI's  technologies  are covered by U.S. and foreign
patents. In addition, CEL-SCI has a number of patent applications pending. There
is no assurance that the applications still pending or which may be filed in the
future will  result in the  issuance of any  patents.  Furthermore,  there is no
assurance as to the breadth and degree of  protection  any issued  patents might
afford  CEL-SCI.  Disputes may arise between  CEL-SCI and others as to the scope
and validity of these or other  patents.  Any defense of the patents could prove
costly and time  consuming and there can be no assurance that CEL-SCI will be in
a position, or will deem it advisable, to carry on such a defense. Other private
and public concerns, including universities, may have filed applications for, or
may have been issued,  patents and are expected to obtain additional patents and
other  proprietary  rights to  technology  potentially  useful or  necessary  to
CEL-SCI.  The scope and  validity of such  patents,  if any, the extent to which
CEL-SCI may wish or need to acquire the rights to such patents, and the cost and
availability  of such  rights are  presently  unknown.  Also,  as far as CEL-SCI
relies upon unpatented proprietary technology, there is no assurance that others
may not  acquire  or  independently  develop  the  same or  similar  technology.
CEL-SCI's first MULTIKINE patent expired in 2000. Since CEL-SCI does not know if
it will ever be able to sell  MULTIKINE on a commercial  basis,  CEL-SCI  cannot
predict  what  effect  the  expiration  of this  patent  will  have on  CEL-SCI.
Notwithstanding the above,  CEL-SCI believes that trade secrets and later issued
patents will protect the technology associated with Multikine.

CEL-SCI's  Product  Liability  Insurance May Not Be Adequate to Protect  CEL-SCI
from Possible Losses.

     Although  CEL-SCI has product  liability  insurance  for  Multikine and its
HGP-30 vaccine,  the successful  prosecution of a product liability case against



CEL-SCI could have a materially  adverse  effect upon its business if the amount
of any judgment exceeds CEL-SCI's insurance coverage.

The Loss of Management and Scientific Personnel Could Adversely Affect CEL-SCI.
- -------------------------------------------------------------------------------

     CEL-SCI is dependent for its success on the continued  availability  of its
executive  officers.  The loss of the  services  of any of  CEL-SCI's  executive
officers  could have an adverse effect on CEL-SCI's  business.  CEL-SCI does not
carry key man life  insurance on any of its officers.  CEL-SCI's  future success
will also depend upon its  ability to attract  and retain  qualified  scientific
personnel.  There  can be no  assurance  that  CEL-SCI  will be able to hire and
retain such necessary personnel.

Shares  Issuable  in  Connection  with the  Equity  Line of  Credit  or Upon the
Conversion of Options, Warrants and Convertible Securities May Depress the Price
of CEL-SCI's Common stock.

     CEL-SCI  has  issued  options to its  officers,  directors,  employees  and
consultants  which allow the holders to acquire  additional  shares of CEL-SCI's
common stock.  In some cases  CEL-SCI has agreed that,  at its expense,  it will
make appropriate filings with the Securities and Exchange Commission so that the
securities  issuable  upon the  exercise of the options  will be  available  for
public sale.  Such filings  could result in  substantial  expense to CEL-SCI and
could hinder future financings by CEL-SCI.

     Until the options  expire,  the holders will have an  opportunity to profit
from any increase in the market price of CEL-SCI's common stock without assuming
the risks of ownership.  Holders of the options may exercise them at a time when
CEL-SCI  could  obtain  additional  capital on terms more  favorable  than those
provided by the  options.  The  exercise  of the options  will dilute the voting
interest of the owners of presently outstanding shares of CEL-SCI's common stock
and may adversely affect the ability of CEL-SCI to obtain additional  capital in
the future. The sale of the shares of common stock issuable upon the exercise of
the options could adversely affect the market price of CEL-SCI's stock.

     In December 1999 and January  2000,  CEL-SCI sold  1,148,592  shares of its
common stock, plus Series A and Series B warrants,  to three private  investors.
The Series A warrants  permit the holders of the  warrants  to purchase  402,007
shares of  CEL-SCI's  common  stock at a price of  $2.925  per share at any time
prior to December 8, 2002. The Series B warrants  allowed the holders to acquire
additional  shares of CEL-SCI's common stock at a nominal price in the event the
price of CEL-SCI's  common  stock fell below  $2.4375 per share prior to certain
fixed  vesting  dates,  the first of which in December  2000. On the first fixed
vesting  date the price of  CEL-SCI's  common  stock was $1.54.  Pursuant to the
terms of the Series B  warrants,  which have since  expired,  the holders of the
warrants,  in December 2000,  received  273,834  additional  shares of CEL-SCI's
common stock.

     In March 2000,  CEL-SCI sold an additional  1,026,666  shares of its common
stock, plus Series C and Series D warrants, to the same three private investors.
The Series C warrants  permit the holders of the  warrants  to purchase  413,344



shares of CEL-SCI's common stock at a price of $8.50 per share at any time prior
to March 21, 2003. The Series D warrants  originally allowed the holders, to the
extent they held any shares  purchased  in the March 2000  offering,  to acquire
additional  shares of CEL-SCI's common stock at a nominal price in the event the
price of  CEL-SCI's  common  stock fell below  $7.50 per share  prior to certain
fixed  vesting  dates,  the first of which was in March 2001. On the first fixed
vesting date the price of CEL-SCI's common stock was $1.47. As a result,  and in
accordance  with the terms of the Series D warrants,  the private  investors are
entitled to receive  4,207,865  additional shares of CEL-SCI's common stock. The
Series D warrants allow the investors,  under certain circumstances,  to acquire
additional shares of CEL-SCI's common stock at a nominal price in the event:

o    The price of CEL-SCI's common stock falls below $1.47 per share or

o    CEL-SCI raises in excess of $1,000,000 at a price which is below either the
     then prevailing market price of CEL-SCI's common stock or $1.47 per share.

     The shares of common stock sold by CEL-SCI in the December 1999 and January
2000 private  offerings have since been resold by the  investors.  The shares of
common stock sold in the March 2000 private  offering,  as well as the shares of
common  stock  issued or  issuable  upon the  exercise  of the Series A, C and D
warrants are being  offered for public sale by means of a separate  registration
statement which has been filed with the Securities and Exchange Commission.  The
sale of common stock  issued or issuable  upon the exercise of the Series A, B C
and D warrants,  or the perception that such sales could occur,  could adversely
affect the market price of CEL-SCI's common stock.

     An unknown number of shares of common stock,  which may be sold by means of
this  prospectus,  are  issuable  under the  equity  line of credit and upon the
exercise of warrants  held by Paul Revere  Capital  Partners.  As CEL-SCI  sells
shares of its common stock to Paul Revere Capital Partners under the equity line
of credit,  and Paul Revere  Capital  Partners  sells the common  stock to third
parties,  the price of CEL-SCI's common stock may decrease due to the additional
shares in the  market.  If CEL-SCI  decides  to draw down on the equity  line of
credit as the price of its common stock  decreases,  CEL-SCI will be required to
issue more shares of its common  stock for any given dollar  amount  invested by
Paul Revere Capital Partners,  subject to the minimum selling price specified by
CEL-SCI.  The more shares that are issued  under the equity line of credit,  the
more  CEL-SCI's then  outstanding  shares will be diluted and the more CEL-SCI's
stock price may decrease. Any decline in the price of CEL-SCI's common stock may
encourage short sales,  which could place further downward pressure on the price
of  CEL-SCI's  common  stock.  See "Equity  Line of Credit  Agreement"  for more
information concerning this equity line.

The Market Price for CEL-SCI's Common Stock is Volatile.

     The market price of CEL-SCI's  common stock,  as well as the  securities of
other  biopharmaceutical  and  biotechnology  companies,  have historically been
highly volatile,  and the market has from time to time  experienced  significant
price and volume fluctuations that are unrelated to the operating performance of
particular  companies.  Factors  such as  fluctuations  in  CEL-SCI's  operating
results,  announcements of technological innovations or new therapeutic products



by CEL-SCI or its competitors,  governmental regulation,  developments in patent
or other  proprietary  rights,  public  concern  as to the  safety  of  products
developed by CEL-SCI or other  biotechnology and pharmaceutical  companies,  and
general market  conditions may have a significant  effect on the market price of
CEL-SCI's common stock.

                             COMPARATIVE SHARE DATA

                                                     Number of          Note
                                                      Shares          Reference

   Shares outstanding as of April 12, 2001          21,116,543

   Shares issuable pursuant to equity line of credit:                     A.

   Shares issuable upon exercise of warrants           200,800            A.

     The number of shares outstanding as of April 12, 2001 excludes shares which
may be issued upon the exercise and/or conversion of options, warrants and other
convertible securities previously issued by CEL-SCI. See table below.

Other Shares Which May Be Issued:
- --------------------------------

     The following table lists additional shares of CEL-SCI's common stock which
may be issued as the result of the exercise of outstanding options,  warrants or
the conversion of other securities issued by CEL-SCI:

                                                  Number of           Note
                                                   Shares           Reference

   Shares issuable upon exercise of               402,007              B.
   Series A warrants

   Shares issuable upon exercise of               413,344              C.
   Series C warrants

   Shares issuable upon exercise of             4,207,865              C.
   Series D warrants

   Shares issuable upon exercise of                25,000              D.
   sales agent warrants

   Shares issuable upon exercise of             1,100,000              E.
   warrants sold to investors in
   December 1997 private offering






   Shares issuable upon exercise of
   options granted to investor relations
   consultants                                    125,000              F.

   Shares issuable upon exercise of
   options and warrants granted to CEL-SCI's
   officers, directors, employees,
   consultants, and third parties               3,493,239              G.

A. An unknown number of shares of common stock, which may be sold by means of
this prospectus, are issuable under the equity line of credit agreement between
CEL-SCI and Paul Revere Capital Partners. As consideration for extending the
equity line of credit, CEL-SCI granted Paul Revere Capital Partners warrants to
purchase 200,800 shares of common stock at a price of $1.64 per share at any
time prior to April 11, 2004. See "Equity Line of Credit Agreement" for more
information concerning this equity line.

B. In December 1999 and January 2000, CEL-SCI sold 1,148,592 shares of its
common stock, plus Series A and Series B warrants, to a group of private
investors for $2,800,000. The Series A warrants allow the holders to purchase up
to 402,007 shares of CEL-SCI's common stock at a price of $2.925 per share at
any time prior to December 8, 2002. The Series B warrants allowed the holders,
to the extent they held any shares purchased in the December 1999 and January
2000 offerings, to acquire additional shares of CEL-SCI's common stock at a
nominal price in the event the price of CEL-SCI's common stock fell below
$2.4375 per share prior to certain fixed vesting dates, the first of which in
December 2000. On the first fixed vesting date the price of CEL-SCI's common
stock was less than $2.4375. As a result, and in accordance with the terms of
the Series B warrants, the private investors were issued 273,834 shares of
CEL-SCI's common stock. The shares of common stock sold by CEL-SCI in the
December 1999 and January 2000 private offerings have since been resold by the
investors and as a result no additional shares are issuable pursuant to the
Series B warrants.

C. In March 2000, CEL-SCI sold 1,026,666 shares of its common stock, plus Series
C and Series D warrants, to the same private investors referred to in Note A for
$7,700,000. The Series C warrants allow the holders to purchase up to 413,344
shares of CEL-SCI's common stock at a price of $8.50 per share at any time prior
to March 21, 2003. The Series D warrants originally allowed the holders, to the
extent the held any shares purchased in the March 2000 offering, to acquire
additional shares of CEL-SCI's common stock at a nominal price in the event the
price of CEL-SCI's common stock fell below $7.50 per share prior to certain
fixed vesting dates, the first of which was in March 2001. On the first fixed
vesting date the price of CEL-SCI's common stock was $1.47. As a result, and in
accordance with the terms of the Series D warrants, the private investors are
entitled to receive 4,207,865 additional shares of CEL-SCI's common stock.






      The remaining fixed vesting dates for the purposes of the Series D
warrants are:

                               September 21, 2001
                                 March 21, 2002
                               September 21, 2002
                                 March 21, 2003

      Other vesting dates will occur when an extraordinary event occurs, such as
a change in the control of CEL-SCI, the bankruptcy or liquidation of CEL-SCI, or
the failure of CEL-SCI's common stock to be listed on the American Stock
Exchange, the NASDAQ Stock Market or the NASDAQ SmallCap market.

      Upon the occurrence of a vesting date, the additional shares (if any)
which CEL-SCI will be required to issue to the holders of the Series D warrants
will be determined in accordance with the following formula:

            [(C x PA) / A]  -  C

          C    = The number of shares  purchased by the Series D warrant  holder
               and not yet sold

          PA   = The Adjustment  Price from the  immediately  preceding  vesting
               date or, with respect to the first vesting date, $1.47.

          A    = Adjustment price, which is equal to the lesser of $1.47, or the
               average of the 10 lowest  closing bid prices of CEL-SCI's  common
               stock  during  the 30  trading  days  immediately  preceding  the
               vesting date.

      In addition to the foregoing, if CEL-SCI raises in excess of $1,000,000
through the sale of common stock, or securities convertible into common stock,
at a price which is below either the then prevailing market price of CEL-SCI's
common stock or the Adjustment Price from the immediately preceding vesting
date, then the holders of the Series D warrants will be entitled to receive
additional shares of CEL-SCI's common stock in accordance with the following
formula:

            [(C x PA) / D]  -  C

            PA          = The Adjustment Price from the immediately preceding
                        vesting date, which was $1.47 as of March 31, 2001.

            C           = The number of shares purchased by the Series D warrant
                        holder and not yet sold on the date of the financing.

            D           = An amount equal to the lesser of the average of the
                        closing bid prices of CEL-SCI's common stock for the 10
                        trading days immediately preceding the date of the



                        financing, or the price per share of the common stock,
                        or common stock equivalent (as the case may be), sold in
                        the financing.

      The actual number of additional shares issuable upon the exercise of the
Series D warrants (if any) will vary depending upon a number of factors,
including the price of CEL-SCI's common stock at certain dates. Accordingly, the
number of shares (if any) which may be issued upon the exercise of the Series D
warrants cannot be determined at this time. However, based upon the market price
of CEL-SCI's common stock on April 12, 2001, CEL-SCI would not be required to
issue any additional shares of its common stock if the Series D warrants were
exercised as of that date.

D. In connection with CEL-SCI's December 1999 sale of common stock and warrants,
Reedland Capital Partners, a division of Financial West Group, acted as the
sales agent for such offering and received a commission of $125,000 plus Series
A warrants to purchase 25,000 shares of CEL-SCI's common stock. The sales agent
warrants are exercisable at a price of $2.925 per share at any time prior to
December 8, 2002.

E. In December 1997, CEL-SCI sold 10,000 shares of its Series D Preferred Stock,
and 1,100,000 warrants, to ten institutional investors for $10,000,000. All
Series D Preferred shares were subsequently converted into 5,201,400 shares of
CEL-SCI's common stock. Warrants for the purchase of 550,000 shares of common
stock are exercisable at a price of $8.62 at any time prior to December 22,
2001. Warrants for the purchase of 550,000 shares of common stock are
exercisable at a price of $9.31 at any time prior to December 22, 2001. As of
April 12, 2001 none of the warrants had been exercised.

F. CEL-SCI has granted options for the purchase of 125,000 shares of common
stock to certain investor relations consultants in consideration for services
provided to CEL-SCI. The options are exercisable at prices ranging between $2.50
and $5.00 per share and expire between June 2000 and February 2004.

G. The options are exercisable at prices ranging from $1.18 to $11.00 per share.
CEL-SCI may also grant options to purchase additional shares under its Incentive
Stock Option and Non-Qualified Stock Option Plans.

      The shares referred to in note A are being offered for sale to the public
by means of this prospectus. The other shares referred to above are being
offered for sale by means of separate registration statements which have been
filed with the Securities and Exchange Commission.

                        MARKET FOR CEL-SCI'S COMMON STOCK

      As of April 12, 2001 there were approximately 2,800 record holders of
CEL-SCI's common stock. CEL-SCI's common stock is traded on the American Stock
Exchange. Set forth below are the range of high and low quotations for CEL-SCI's
common stock for the periods indicated as reported the American Stock Exchange.
The market quotations reflect inter-dealer prices, without retail mark-up,
mark-down or commissions and may not necessarily represent actual transactions.




         Quarter Ending                 High             Low
         --------------                 ----             ---
          12/31/98                     $3.50            $1.50
           3/31/99                     $2.75            $1.63
           6/30/99                     $3.38            $1.81
           9/30/99                     $3.81            $1.88

          12/31/99                     $3.06            $2.18
           3/31/00                     $9.87            $2.25
           6/30/00                     $6.37            $2.75
           9/30/00                     $3.56            $2.20

          12/31/00                     $2.54            $1.00
           3/31/01                     $3.30            $1.30

      Holders of Common Stock are entitled to receive such dividends as may be
declared by the Board of Directors out of funds legally available therefor and,
in the event of liquidation, to share pro rata in any distribution of CEL-SCI's
assets after payment of liabilities. The Board of Directors is not obligated to
declare a dividend. CEL-SCI has not paid any dividends on its common stock and
CEL-SCI does not have any current plans to pay any common stock dividends.

      The provisions in CEL-SCI's Articles of Incorporation relating to
CEL-SCI's Preferred Stock would allow CEL-SCI's directors to issue Preferred
Stock with rights to multiple votes per share and dividend rights which would
have priority over any dividends paid with respect to CEL-SCI's Common Stock.
The issuance of Preferred Stock with such rights may make more difficult the
removal of management even if such removal would be considered beneficial to
shareholders generally, and will have the effect of limiting shareholder
participation in certain transactions such as mergers or tender offers if such
transactions are not favored by incumbent management.

      The market price of CEL-SCI's common stock, as well as the securities of
other biopharmaceutical and biotechnology companies, have historically been
highly volatile, and the market has from time to time experienced significant
price and volume fluctuations that are unrelated to the operating performance of
particular companies. Factors such as fluctuations in CEL-SCI's operating
results, announcements of technological innovations or new therapeutic products
by CEL-SCI or its competitors, governmental regulation, developments in patent
or other proprietary rights, public concern as to the safety of products
developed by CEL-SCI or other biotechnology and pharmaceutical companies, and
general market conditions may have a significant effect on the market price of
CEL-SCI's Common Stock.






           MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                            AND RESULTS OF OPERATIONS

      The following selected financial data should be read in conjunction with
the more detailed financial statements, related notes and other financial
information included in this prospectus.

                                     For the Years Ended September 30,
                           -----------------------------------------------------

                              2000        1999        1998      1997       1996
                              ----        ----        ----      ----       ----
Investment Income and
  Other Revenues:           $442,551   $469,518   $792,994   $438,145   $322,370

Expenses:
Research and Development   4,978,714  4,461,051  3,833,854  6,011,670  3,471,477
Depreciation and
  Amortization               220,994    268,210    295,331    313,547    290,829
General and
  Administrative           3,721,240  3,230,982  3,106,492  2,302,386  2,882,958
Equity in loss of joint
  venture                         --         --         --         --      3,772
                               -------------------------------------------------

Net Loss            $(8,478,397)$(7,490,725)$(6,442,683)$(8,189,458)$(6,326,666)
                    ======================== ===================================

Loss per common share
(basic and diluted)       $(0.44)     $(0.52)    $(0.74)   $(1.00)     $(1.16)

Weighted average common
  Shares outstanding   19,259,190  14,484,352  11,379,437  9,329,419  6,425,316

                                                   Three Months Ended
                                                      December 31,
                                               -------------------------
                                               2000               1999
                                               ----               ----

Investment Income and Other
  Revenues:                                 $249,808            $30,048

Expenses:
Research and Development                   2,017,007            995,024
Depreciation and Amortization                 49,079             70,780
General and Administrative                   727,211            668,652
                                             -------            -------

Net Loss                                 $(2,543,489)       $(1,734,456)
                                         ============       ============

Loss per common share
  (basic and diluted)                         $(0.12)            $(0.10)

Weighted average common
  shares outstanding                      20,459,913         17,270,008






Balance Sheet Data:
- ------------------

                                    September 30,
                    -----------------------------------------------------------

                      2000        1999        1998         1997         1996
                      ----        ----        ----         ----         ----

Working Capital    $11,725,940  $6,152,715  $12,926,014  $4,581,247  $10,266,104
Total Assets        13,808,882   7,559,772   14,431,813   6,334,397   11,878,370
Total Liabilities      847,423     461,586      456,529     508,617      294,048
Shareholders'
  Equity            12,961,459   7,098,186   13,975,284   5,825,780   11,584,322

                              December 31, 2000

Working Capital                 $9,230,208
Total Assets                    11,263,832
Total Liabilities                  789,854
Shareholders' Equity            10,473,978

No dividends have been declared on CEL-SCI's common stock.

Results of Operations

Three Months Ended December 31, 2000

     Interest income during the three months ending December 31, 2000 was higher
than it was during the same quarter in 1999 as a result of CEL-SCI's larger cash
position. Research and development expenses were significantly higher because of
the expenses incurred in the validation of the new  manufacturing  facilities at
BSCP.  While the expenses during the next fiscal quarter are expected to be high
again for the same reason, CEL-SCI's cash outflow will decrease significantly in
the next  quarter  since  the  majority  of the  expenses  at BSCP  are  prepaid
($1,750,000  at December 31,  2000).  General and  administrative  expenses have
increased  mostly  because of the  significantly  higher  bills  from  CEL-SCI's
auditors and higher salaries.

Fiscal 2000

      Interest income during the year ended September 30, 2000 reflects interest
received and accrued on investments. Research and development expense in 2000 is
higher than in 1999 because CEL-SCI is running more and larger clinical trials.
General and administrative expenses have increased due to the lawsuit brought by
former directors which was settled in May of 2000.

Fiscal 1999

    Interest income during the year ending September 30, 1999 reflects interest
received and accrued on investments. Interest income decreased as CEL-SCI used
the proceeds of the sale of the Series D Preferred Stock. Research and
development expense in 1999 was higher than in 1998 because CEL-SCI is running
more and larger clinical trials. General and administrative expenses have
increased due to the addition of more employees needed for the increased
activity level.




Fiscal 1998

      Interest income during the year ending September 30, 1998 reflects
interest accrued on investments. Interest income increased from fiscal 1997 due
to the investment of the proceeds of the sale of the Series D Preferred Stock.
Research and development expenses in 1998 are substantially less then the prior
period since the costs of acquiring the MULTIKINE license and the L.E.A.P.S.
technology were expensed in fiscal 1997. General and administrative expenses
increased due to additional employees needed for CEL-SCI's increased activity
level and charges ($587,377) for options granted to persons other than employees
with exercise prices equal to prevailing market prices at the time of grant.

Liquidity and Capital Resources

      CEL-SCI has had only limited revenues from operations since its inception
in March l983. CEL-SCI has relied upon proceeds realized from the public and
private sale of its Common Stock to meet its funding requirements. Funds raised
by CEL-SCI have been expended primarily in connection with the acquisition of an
exclusive worldwide license to certain patented and unpatented proprietary
technology and know-how relating to the human immunological defense system,
patent applications, the repayment of debt, the continuation of
Company-sponsored research and development, administrative costs and
construction of laboratory facilities. Inasmuch as CEL-SCI does not anticipate
realizing revenues until such time as it enters into licensing arrangements
regarding the technology and know-how licensed to it (which could take a number
of years), CEL-SCI is mostly dependent upon the proceeds from the sale of its
securities to meet all of its liquidity and capital resource requirements.

      In August 1996, CEL-SCI sold, in a private transaction, 5,000 shares of
its Series B Convertible Preferred Stock for $5,000,000 or $1,000 per share.
Prior to December 20, 1996, 1,900 Series B Preferred Shares were converted into
527,774 shares of CEL-SCI's common stock. In December 1996 CEL-SCI repurchased
2,850 Series B Preferred Shares for $2,850,000 plus warrants which allowed the
holders to purchase up to 99,750 shares of CEL-SCI's common stock for $4.25 per
share at any time prior to December 15, 1999. CEL-SCI raised funds required for
this repurchase from the sale of its Series C Preferred Stock. In May 1997 all
remaining 250 shares of the Series B Preferred Stock were converted into 69,444
shares of common stock. In October 1997 17,500 warrants were exercised at $4.25
per share. On December 15, 1999 the remaining 82,250 warrants expired.

       In December 1997, CEL-SCI sold 10,000 shares of its Series D Convertible
Preferred Stock, 550,000 Series A Warrants and 550,000 Series B Warrants, to ten
institutional investors for $10,000,000. Each Series A Warrant allows the holder
to purchase one share of CEL-SCI's common stock for $8.62 at any time prior to
December 22, 2001. Each Series B Warrant allows the holder to purchase one share
of CEL-SCI's Common Stock for $9.31 at any time prior to December 22, 2001.
CEL-SCI has filed a registration statement with the Securities and Exchange
Commission covering the sale of the common stock issuable upon the conversion of



the Series D Preferred Stock and/or the exercise of the Series A and Series B
Warrants. As of December 15, 1999 all Series D Preferred Shares had been
converted into 5,201,460 shares of CEL-SCI's common stock. None of the Series A
or Series B warrants have been exercised.

      In December 1999 and January 2000, CEL-SCI sold 1,148,592 shares of its
common stock, plus Series A and Series B warrants, to a group of private
investors for $2,800,000. The Series A warrants allow the holders to purchase up
to 402,007 shares of CEL-SCI's common stock at a price of $2.925 per share at
any time prior to December 8, 2002. The Series B warrants allowed the holders,
to the extent they held any shares purchased in the December 1999 and January
2000 offerings, to acquire additional shares of CEL-SCI's common stock at a
nominal price in the event the price of CEL-SCI's common stock fell below
$2.4375 per share prior to certain fixed vesting dates, the first of which in
December 2000. On the first fixed vesting date the price of CEL-SCI's common
stock was $1.54. As a result, and in accordance with the terms of the Series B
warrants, the private investors were issued 273,834 shares of CEL-SCI's common
stock. The shares of common stock sold by CEL-SCI in the December 1999 and
January 2000 private offerings have since been resold by the investors and as a
result no additional shares are issuable pursuant to the Series B warrants.

      In March 2000, CEL-SCI sold 1,026,666 shares of its common stock, plus
Series C and Series D warrants, to the same private investors referred to in
Note A for $7,700,000. The Series C warrants allow the holders to purchase up to
413,344 shares of CEL-SCI's common stock at a price of $8.50 per share at any
time prior to March 21, 2003. The Series D warrants originally allowed the
holders, to the extent they held any shares purchased in the March 2000
offering, to acquire additional shares of CEL-SCI's common stock at a nominal
price in the event the price of CEL-SCI's common stock fell below $7.50 per
share prior to certain fixed vesting dates, the first of which was in March
2001. On the first fixed vesting date the price of CEL-SCI's common stock was
$1.47. As a result, and in accordance with the terms of the Series D warrants,
the private investors are entitled to receive 4,207,865 additional shares of
CEL-SCI's common stock.

      During fiscal 2001, CEL-SCI expects that it will spend approximately
$5,000,000 on research, development, and clinical trials. CEL-SCI plans to use
its existing financial resources as well as the proceeds from the sale of its
common stock under the equity line of credit agreement with Paul Revere Capital
Partners to fund its capital requirements during this period.

      Other than funding its research and development program, CEL-SCI does not
have any material capital commitments.

      It should be noted that substantial additional funds will be needed for
more extensive clinical trials which will be necessary before CEL-SCI will be
able to apply to the FDA for approval to sell any products which may be
developed on a commercial basis throughout the United States. In the absence of
revenues, CEL-SCI will be required to raise additional funds through the sale of
securities, debt financing or other arrangements in order to continue with its
research efforts. However, there can be no assurance that such financing will be
available or be available on favorable terms.




                                    BUSINESS

      CEL-SCI Corporation was formed as a Colorado corporation in 1983. CEL-SCI
is involved in the research and development of the drugs and vaccines described
below.

MULTIKINE

      CEL-SCI's first, and main, product, MULTIKINE(TM), manufactured using
CEL-SCI's proprietary cell culture technologies, is a combination, or
"cocktail", of natural human interleukin-2 ("IL-2") and certain lymphokines and
cytokines. MULTIKINE is being tested to determine if it is effective in
improving the immune response of cancer patients.

      MULTIKINE has been tested in over 150 patients in the past few years in
clinical trials conducted in the U.S., Canada, Europe and Israel. Most of these
patients were head and neck cancer patients, but some studies were also
conducted in prostate cancer patients and HIV-infected patients. The safety
profile was found to be very good and CEL-SCI believes that the tumor response
data suggest that further studies are warranted.

      CEL-SCI's primary focus for the development of MULTIKINE is to prove its
usefulness in the treatment of head and neck cancer, which constitutes about 6%
of all cancer worldwide. CEL-SCI is currently conducting three additional head
and neck cancer studies to determine the best regimen for treating the patients.

      With a secondary focus, CEL-SCI is also conducting studies with MULTIKINE
in prostate cancer patients and is planning to start a cervical cancer study by
the second quarter of 2001. Although CEL-SCI has the approval to start a 20
patient breast cancer study in Israel, given the current problems in that
region, CEL-SCI will not pursue this study at the present time.

      The function of the immunological system is to protect the body against
infectious agents, including viruses, bacteria, parasites and malignant (cancer)
cells. An individual's ability to respond to infectious agents and to other
substances (antigens) recognized as foreign by the body's immune system is
critical to health and survival. When the immune response is adequate, infection
is usually combated effectively and recovery follows. Severe infection can occur
when the immune response is inadequate. Such immune deficiency can be present
from birth but, in adult life, it is frequently acquired as a result of intense
sickness or as a result of the administration of chemotherapeutic drugs and/or
radiation. It is also recognized that, as people reach middle age and
thereafter, the immune system grows weaker.

     Two classes of white blood cells, macrophages and lymphocytes, are believed
to be primarily  responsible  for  immunity.  Macrophages  are large cells whose
principal  immune  activity  is  to  digest  and  destroy   infectious   agents.
Lymphocytes  are divided into two  sub-classes.  One  sub-class of  lymphocytes,
B-cells,  produces  antibodies in response to antigens.  Antibodies  have unique
combining sites  (specificities) that recognize the shape of particular antigens
and bind with them.  The  combination  of an  antibody  with an antigen  sets in
motion a chain of  events  which  may  neutralize  the  effects  of the  foreign
substance.  The  other  sub-class  of  lymphocytes,  T-cells,  regulates  immune
responses.  T-cells,  for  example,  amplify or suppress  antibody  formation by



B-cells,  and can also directly  destroy  "foreign" cells by activating  "killer
cells."

      It is generally recognized that the interplay among T-cells, B-cells and
the macrophages determines the strength and breadth of the body's response to
infection. It is believed that the activities of T-cells, B-cells and
macrophages are controlled, to a large extent, by a specific group of hormones
called cytokines. Cytokines regulate and modify the various functions of both
T-cells and B-cells. There are many cytokines, each of which is thought to have
distinctive chemical and functional properties. IL-2 is but one of these
cytokines and it is on IL-2 and its synergy with other cytokines that CEL-SCI
has focused its attention. Scientific and medical investigation has established
that IL-2 enhances immune responses by causing activated T-cells to proliferate.
Without such proliferation no immune response can be mounted. Other cytokines
support T-cell and B-cell proliferation. However, IL-2 is the only known
cytokine which causes the proliferation of T-cells. IL-2 is also known to
activate B-cells in the absence of B-cell growth factors.

      Although IL-2 is one of the best characterized cytokines with anticancer
potential, CEL-SCI is of the opinion that to have optimum therapeutic value,
IL-2 should be administered not as a single substance but rather as a mixture of
IL-2 and certain cytokines, i.e. as a "cocktail". This approach, which was
pioneered by CEL-SCI, makes use of the synergism between these cytokines. It
should be noted, however, that neither the FDA nor any other agency has
determined that CEL-SCI's MULTIKINE product will be effective against any form
of cancer.

      It has been reported by researchers in the field of cytokine research that
IL-2 can increase the number of killer T-cells produced by the body, which
improves the body's capacity to selectively destroy specific tumor cells.
Research and human clinical trials sponsored by CEL-SCI have indicated a
correlation between administration of MULTIKINE to cancer patients and
immunological responses. On the basis of these experimental results, CEL-SCI
believes that MULTIKINE may have application for the treatment of solid tumors
in humans.

      In November 1990, the Florida Department of Health and Rehabilitative
Services ("DHRS") gave the physicians at a southern Florida medical institution
approval to start a clinical cancer trial in Florida using CEL-SCI's MULTIKINE
product. The focus of the trial was unresectable head and neck cancer.

      In 1991, four patients with regionally advanced squamous cell cancer of
the head and neck were treated with CEL-SCI's MULTIKINE product. The patients
had previously received radical surgery followed by x-ray therapy but developed
recurrent tumors at multiple sites in the neck and were diagnosed with terminal
cancer. The patients had low levels of lymphocytes and evidence of immune
deficiency (generally a characteristic of this type of cancer).

      Significant tumor reduction occurred in three of the four patients as a
result of the treatment with MULTIKINE. Negligible side effects were observed
and the patients were treated as outpatients. Notwithstanding the above, it
should be noted that these trials were only preliminary and were only conducted
on a small number of patients. It remains to be seen if MULTIKINE will be
effective in treating any form of cancer.




      These results caused CEL-SCI to embark on a major manufacturing program
for MULTIKINE with the goal of being able to produce a drug that would meet the
stringent regulatory requirements for advanced human studies. This program
included building a pilot scale manufacturing facility.

      Since that time, MULTIKINE has been well tolerated in clinical studies
involving more than 150 patients. Some of the more recent clinical data were
presented at the 5th International Congress on Head and Neck Cancer in San
Francisco in August, 2000. The study enrolled advanced primary head and neck
cancer patients who were treated prior to surgery and/or radiation for 2 weeks.
Dr. Dudkevitch from the Department of Otolaryngology at the Rabin Medical
Center, Israel, presented data showing that, of the 12 patients treated, two
patients had a complete tumor response (100% tumor reduction) following the
2-week treatment with the MULTIKINE regimen. He also noted that upon
histopathological examination of the tissue removed during surgery, no tumor
residues were found in those patients. Another 4 patients showed a partial
(greater than 50%) tumor reduction and six patients had tumor reductions of less
than 50%. Two patients refused surgery after treatment with MULTIKINE.

      The researcher also reported that several of the patients had increased
tongue mobility and/or reduction or elimination of local pain. These are
considered to be important indicators for the patient's quality of life. There
were no tumor progressions or adverse local changes, nor was there evidence of
toxicity from MULTIKINE. Both recovery after operation and wound healing were
normal.

      A substantial part of the oral presentation was spent on a discussion of
the pathology findings. The researchers reported that from biopsy samples of 10
patients analyzed before and after treatment, an increase in the degree of
lymphocytic infiltration was noted in 5 patients. Of special interest was the
new post-treatment appearance of multinucleated histiocytes in 5 patients with
significant tumor reductions. The multinucleated histiocytes were detected in
two specific locations, namely around the keratin debris and in the tumor-stroma
interface, and they appear to be actively engulfing the tumor cells.

      Promising results were also seen in other clinical studies, most of which
tested different dosages and routes of administration, although tumor reductions
were not as significant as those noted in the Israeli study. The focus of three
new studies involving an additional 60 patients is to define the best treatment
regimen for Multikine.

      CEL-SCI also plans to start a Phase I clinical trial with Edmund Tramont,
M.D., of the University of Maryland Biotechnology Institute's (UMBI) in May 2001
in HIV and HPV (Human Papilloma Virus) co-infected women with cervical cancer.
The goal of the study is to obtain safety and preliminary efficacy data on
Multikine as a treatment for pre-cancerous lesions of the cervix (dysplasia) and
human cancer/neoplasia. Most cervical dysplasia and cancer is due to infection
with HPV. The rationale for using MULTIKINE in the treatment of cervical cancer
is that MULTIKINE will help correct this defect and safely boost the patients'
immune systems to a point where their immune systems can fight and eliminate the
virally induced cancer.




      Similar efforts are underway in prostate cancer. However, due to the size
of CEL-SCI's clinical department, CEL-SCI has been unable to move aggressively
in this area.

      In November 2000, CEL-SCI concluded a development, supply and distribution
agreement with Orient Europharma of Taiwan. The agreement gives Orient
Europharma the exclusive marketing rights to Multikine for all cancer
indications in Taiwan, Singapore, Hong Kong and Malaysia. The agreement provides
for Orient Europharma to fund the clinical trials needed to obtain marketing
approvals in the four countries for head and neck cancer, nasal pharyngeal
cancer and potentially cervical cancer, which are very prevalent in Far East
Asia. CEL-SCI may use the clinical data generated in these trials to support
applications for marketing approvals for Multikine in other parts of the world.

      Under the agreement, CEL-SCI will manufacture Multikine and Orient
Europharma will purchase the product from CEL-SCI for distribution in the
territory. Both parties will share in the revenue from the sale of Multikine.

      Head and neck cancer is the sixth most frequently occurring cancer
worldwide, with an incidence of 500,000 annually. Recent statistics show no
reduction in head and neck cancer mortality, but rather a dramatic increase of
the disease in certain segments of the population. This cancer is most
frequently found in men in their 50's or early 60's with a history of smoking
and alcohol consumption. Conventional treatment calls for either surgery, which
can be extremely disfiguring, or radiation and chemotherapy, both of which are
associated with very unpleasant side-effects.

      Proof of efficacy for anti-cancer drugs is a lengthy and complex process.
At this early stage of clinical investigation, it remains to be proven that
MULTIKINE will be effective against any form of cancer. Even if some form of
MULTIKINE is found to be effective in the treatment of cancer, commercial use of
MULTIKINE may be several years away due to extensive safety and effectiveness
tests that would be necessary before required government approvals are obtained.
It should be noted that other companies and research teams are actively involved
in developing treatments and/or cures for cancer, and accordingly, there can be
no assurance that CEL-SCI's research efforts, even if successful from a medical
standpoint, can be completed before those of its competitors.

      CEL-SCI uses an unrelated corporation for certain aspects of the
production of MULTIKINE for research and testing purposes. The agreement with
this corporation expires in 2006.

T-CELL MODULATION PROCESS

      In January 1996, CEL-SCI acquired a new patented T-cell Modulation Process
which uses "heteroconjugates" to direct the body to choose a specific immune
response. The heteroconjugate technology, referred to as L.E.A.P.S. (Ligand
Epitope Antigen Presentation System), is intended to selectively stimulate the
human immune system to more effectively fight bacterial, viral and parasitic
infections and cancer, when it cannot do so on its own. Administered like



vaccines, L.E.A.P.S. combines T-cell binding ligands with small, disease
associated, peptide antigens and may provide a new method to treat and prevent
certain diseases.

      The ability to generate a specific immune response is important because
many diseases are often not combated effectively due to the body's selection of
the "inappropriate" immune response. The capability to specifically reprogram an
immune response may offer a more effective approach than existing vaccines and
drugs in attacking an underlying disease.

      CEL-SCI intends to use this technology to develop potential treatments
and/or vaccines against various diseases. Present target diseases are herpes
simplex, AIDS, malaria, tuberculosis, prostate cancer and breast cancer.

      In August 1996, CEL-SCI signed a Cooperative Research and Development
Agreement ("CRADA") with the Naval Medical Research Institute of the U.S. Navy
to jointly develop a potential malaria vaccine using CEL-SCI's L.E.A.P.S.
technology. This agreement was extended in 1998 and again in 2000. Malaria
affects about 300-500 million people per year and is responsible for about 2.7
million deaths annually. It is a parasitic disease transmitted by mosquitoes. As
with tuberculosis, the emergence of drug resistant strains is a major problem,
as is the emergence of mosquitoes which are resistant to traditional
insecticides. While at present the number of malaria cases is not a major
problem in the continental U.S., there are an increasing number of cases
involving Americans bringing the disease home from overseas travels. Currently,
there is no approved malaria vaccine anywhere in the world.

      The large majority of the malaria studies were conducted in outbred CD-1
mice, which may be more representative of a human population than inbred mice.
Protection against rodent malaria in those experiments was observed in 62-70% of
the vaccinated animals compared to protection levels between 0-30% observed in
the control groups.

      The L.E.A.P.S. construct used in this study was a combination of a peptide
representing a mouse malaria epitope linked to another peptide, called the
T-cell binding ligand, which was designed to specifically stimulate the immune
system. Each of these two peptides was given individually as a control. In all
experiments, the level of protection achieved after immunization with the
L.E.A.P.S. construct was significantly higher than when the two peptides were
given individually.

      The studies showed that the protective immune responses required the
presence of T- cells having a marker called CD4, typically found on helper T-
cells, as well as the presence of gamma Interferon, which suggests that a
cellular immune response may be involved in protection.

      In October 1996, CEL-SCI and Northeastern Ohio University College of
Medicine signed a Collaborative Research Agreement to jointly identify and
evaluate Herpes Simplex Virus related peptides. This study made use of CEL-SCI's
LEAPS technology which combines T-cell binding ligands with small, disease
associated, peptide antigens. In the past, some vaccines have worked simply by
vaccination with viral proteins (e.g. hepatitis B) to immunize patients. In the
case of herpes simplex, that strategy has yet to be proven successful. The



purpose of adding the T-cell binding ligand was to increase the effectiveness of
the vaccine by directing the immune response to react in the way most likely to
eliminate or control the disease agent. To test this hypothesis in herpes
simplex, the researchers administered the vaccine with a T-cell binding ligand
to one group of mice in order to direct the immune response to the cellular
side, which is thought to be protective. The researchers also administered the
vaccine to a separate group of mice using a different T-cell binding ligand to
direct the immune response to the humoral (antibody) side, which is thought to
be non-protective. For both vaccines, the herpes simplex peptide was kept the
same. The results of the study indicated that the immunizations allowed the mice
to resolve the infection quicker and more effectively resulting in minimal
symptoms and mortality. The vaccine inducing a cellular immune response was
protective while the vaccine inducing a humoral (antibody) immune response was
not protective and actually accelerated disease progression. Two studies with
different herpes simplex peptides also showed protection, confirming the results
from the prior study. Research conducted pursuant to this study may lead to the
future development of a herpes simplex vaccine.

      In May 1998, CEL-SCI announced the receipt of a Phase I $100,000 research
grant to fund further animal studies with its herpes simplex vaccine. This grant
was given pursuant to the Small Business Innovation Research Program of the
National Institute of Allergy and Infectious Diseases.

      In October 2000, CEL-SCI received approval for funding of a Phase II grant
from the National Institute of Allergy and Infectious Diseases. This grant was
awarded following the successful completion of studies, funded by the Phase I
grant, which showed increased protection from death in an animal challenge model
of herpes simplex. The Phase II grant, worth about $764,000 over two years, will
support the further development of a herpes simplex virus vaccine based on
CEL-SCI's L.E.A.P.S. technology.

      Conservative estimates of those individuals who have genital infections
are 30-40 million in the U.S. Oral herpetic infections are of a greater
frequency. In newborns or in immunosuppressed patients (e.g. AIDS), herpes can
lead to serious illness and death. Vaccination against herpes simplex virus may
prevent or treat herpes simplex infection. Unlike most other viruses, once
infected, a herpes virus remains in hiding within an individual and is
reactivated often by stress-inducing factors. For some individuals, recurrences
may take place on a monthly basis. Although there are antiviral drugs which are
used to prevent serious disease and lessen the symptoms, there is currently no
method to effectively prevent initial infection, to eliminate the virus from an
infected person, or to prevent recurrences.

      Scientists at Northeastern Ohio University College of Medicine have been
working on methods of treating and detecting the herpes virus for over fifteen
years.

      In November 1999, CEL-SCI announced a collaborative study for the
treatment, and possible prevention, of autoimmune myorcarditis with researchers
at the Department of Pathology, the Johns Hopkins Medical Institutions,
Baltimore, Maryland.

     Myocarditis,  an autoimmune  disease affecting the heart muscle, is thought
to be caused by an attack on the  patient's  heart  muscle by his/her own immune



cells and  antibodies.  Myocarditis  is a precursor  to dilated  cardiomyopathy,
which is an end stage cardiac disease usually requiring a heart transplant.  The
incidence of dilated cardiomyopathy is about 200,000 people in the United States
alone. The current treatments are not curative.

     The  study  will use  L.E.A.P.S.(TM)  technology,  as well as a  technology
recently developed at CEL-SCI and called AdapT (Antigen Directed Apoptosis). The
AdapT  technology  is designed to lead to the  removal,  in an antigen  specific
(highly  targeted)  manner,  of only those  immune  system  cells that cause the
disease,  thereby  leaving  the  remainder  of the  immune  response  intact and
subsequently able to defend against other diseases.

      The goal of the first phase of this animal study is to establish the
animal model of autoimmune myocarditis, using the L.E.A.P.S technology. In the
second phase, AdapT and L.E.A.P.S. derived peptides may be used, in the case of
the L.E.AP.S., to divert immune responses away from the disease-causing immune
system cells or, in the case of AdapT, to remove the disease-causing immune
system cells.

     If the  L.E.A.P.S.  or AdapT  technologies  are shown to work in the animal
model  for  myocarditis,  additional  studies  may be  started  to test this new
approach for the treatment of other autoimmune diseases as well.

     In  November  1999,  CEL-SCI  also  announced  that it has  entered  into a
research  collaboration  agreement with research  scientists at the Max-Delbruck
Center for Molecular Medicine in Berlin,  Germany. The goal of the collaboration
is to develop a therapeutic vaccine for breast and/or colon cancer.

     The  collaboration  will  make  use  of  the  L.E.A.P.S.   technology,   in
combination  with the  specialized  cancer  antigen  and  animal  testing  model
knowledge of the team in Berlin.  The work is being conducted under the umbrella
of the  Biological  Therapeutic  Development  Group of the  European  Office for
Research and Treatment of Cancer.

     The  L.E.A.P.S.   technology  was  acquired  from  Cell-Med,   Incorporated
("CELL-MED")  in  consideration  for  CEL-SCI's  payment  of  $56,000  plus  the
issuance,  during 1996, of 33,378 shares of CEL-SCI's common stock. CEL-SCI must
pay CELL-MED  additional  payments of up to $600,000,  depending  upon CEL-SCI's
ability to obtain regulatory approval for clinical studies using the technology.
In  addition,  should  CEL-SCI  receive FDA approval for the sale of any product
incorporating  the  technology,  CEL-SCI is obligated to pay CELL-MED an advance
royalty of $500,000, a royalty of 5% of the sales price of any product using the
technology, plus 15% of any amounts CEL-SCI receives as a result of sublicensing
the technology. So long as CEL-SCI retains rights in the technology, CEL-SCI has
also agreed to pay the future costs associated with pursuing and/or  maintaining
CELL-MED's  patents  and patent  applications  relating to the  technology.  The
technology  obtained  from  CELL-MED  is covered by several  U.S.  and  European
patents. Additional patent applications are pending.






AIDS VACCINE

      Prior to 2001, CEL-SCI was involved in the development of a preventive
vaccine against HIV infection. During 2000 CEL-SCI completed Phase II human
clinical trials with this vaccine in the Netherlands. The vaccine, which is
derived from CEL-SCI's HGP-30 technology, is primarily directed against HIV
subtype C, the most prevalent HIV subtype in Africa and other third world
countries. HGP-30 is a thirty amino acid region of the p17 core protein of HIV.
CEL-SCI holds proprietary rights to certain synthesized components of the p17
core protein. The HGP-30 vaccine differs from most other vaccine candidates in
that its active component, the HGP-30 peptide, is derived from the p17 core
protein particles of the virus. Since HGP-30 is a totally synthetic molecule
containing no live virus, it cannot cause infection. Unlike the envelope (i.e.
outside) proteins, the p17 region of the AIDS virus appears to be relatively
non-changing. HGP-30 may also be effective in treating persons infected with the
AIDS virus. Currently CEL-SCI is no longer pursuing further development of its
AIDS vaccine and is attempting to license this technology to a third party.

RESEARCH AND DEVELOPMENT

      Since 1983, and through September 30, 2000, approximately $32,245,000 has
been expended on CEL-SCI-sponsored research and development, including
approximately $4,982,000, $4,461,000 and $3,834,000, respectively during the
years ended September 30, 2000, 1999 and 1998.

      The costs associated with the clinical trials relating to CEL-SCI's
technologies, research expenditures and CEL-SCI's administrative expenses have
been funded with the public and private sales of shares of CEL-SCI's common
stock and borrowings from third parties, including affiliates of CEL-SCI.

      CEL-SCI has a Scientific Advisory Board ("SAB") comprised of scientists
distinguished in biomedical research in the field of cytokines and related
areas. From time to time, members of the SAB advise CEL-SCI on its research
activities. Institutions with which members of the SAB are affiliated have in
the past conducted and may in the future conduct Company-sponsored research. The
SAB has in the past and may in the future, at its discretion, invite other
scientists to opine in confidence on the merits of CEL-SCI-sponsored research.
Members of the SAB receive $500 per month from CEL-SCI.

      The members of CEL-SCI's SAB are:

     Evan M. Hersh,  M.D. - Professor of Medicine,  Microbiology and Immunology,
Assistant  Director of Experimental  Therapeutics  and  Translational  Research,
Arizona Cancer Center, Tucson.

     Michael J.  Mastrangelo,  M.D. - Professor of Medicine,  Jefferson  Medical
College, Philadelphia,  Pennsylvania; and Associate Clinical Director, Jefferson
Cancer Center, Philadelphia, Pennsylvania.




     Alan B. Morris,  Ph.D.  - Professor,  Department  of  Biological  Sciences,
University of Warwick, Coventry, U.K.

     Edmond C.  Tramont,  M.D. - Associate  Director of The  Institute  of Human
Virology, University of Maryland Biotechnology Institute.

GOVERNMENT REGULATION

      The investigational agents and future products of CEL-SCI are regulated in
the United States under the Federal Food, Drug and Cosmetic Act, the Public
Health Service Act, and the laws of certain states. The Federal Food and Drug
Administration (FDA) exercises significant regulatory control over the clinical
investigation, manufacture and marketing of pharmaceutical and biological
products.

      Prior to the time a pharmaceutical product can be marketed in the United
States for therapeutic use, approval of the FDA must normally be obtained.
Certain states, however, have passed laws which allow a state agency having
functions similar to the FDA to approve the testing and use of pharmaceutical
products within the state. In the case of either FDA or state regulation,
preclinical testing programs on animals, followed by three phases of clinical
testing on humans, are typically required in order to establish product safety
and efficacy.

      The first stage of evaluation, preclinical testing, must be conducted in
animals. After lack of toxicity has been demonstrated, the test results are
submitted to the FDA (or state regulatory agency) along with a request for
clearance to conduct clinical testing, which includes the protocol that will be
followed in the initial human clinical evaluation. If the applicable regulatory
authority does not object to the proposed study, the investigator can proceed
with Phase I trials. Phase I trials consist of pharmacological studies on a
relatively few number of humans under rigidly controlled conditions in order to
establish lack of toxicity and a safe dosage range.

      After Phase I testing is completed, one or more Phase II trials are
conducted in a limited number of patients to test the product's ability to treat
or prevent a specific disease, and the results are analyzed for clinical
efficacy and safety. If the results appear to warrant confirmatory studies, the
data is submitted to the applicable regulatory authority along with the protocol
for a Phase III trial. Phase III trials consist of extensive studies in large
populations designed to assess the safety of the product and the most desirable
dosage in the treatment or prevention of a specific disease. The results of the
clinical trials for a new biological drug are submitted to the FDA as part of a
product license application ("PLA"), a New Drug Application ("NDA") or Biologics
License Application ("BLA"), depending on the type or derivation of the product
being studied.

      In addition to obtaining FDA approval for a product, a biologics
establishment license application ("ELA") may need to be filed in the case of
biological products derived from blood, or not considered to be sufficiently
well characterized, in order to obtain FDA approval of the testing and
manufacturing facilities in which the product is produced. To the extent all or
a portion of the manufacturing process for a product is handled by an entity



other than CEL-SCI, CEL-SCI must similarly receive FDA approval for the other
entity's participation in the manufacturing process. Domestic manufacturing
establishments are subject to inspections by the FDA and by other Federal, state
and local agencies and must comply with Good Manufacturing Practices ("GMP") as
appropriate for production. In complying with GMP regulations, manufacturers
must continue to expend time, money and effort in the area of production,
quality control and quality assurance to ensure full technical compliance.

      The process of drug development and regulatory approval requires
substantial resources and many years. Approval of drugs and biologicals by
regulatory authorities of most foreign countries must also be obtained prior to
initiation of clinical studies and marketing in those countries. The approval
process varies from country to country and the time period required in each
foreign country to obtain approval may be longer or shorter than that required
for regulatory approval in the United States.

      There are no assurances that clinical trials conducted under approval from
state authorities or conducted in foreign countries will be accepted by the FDA.
Product licensure in a foreign country does not mean that the product will be
licensed by the FDA and there are no assurances that CEL-SCI will receive any
approval of the FDA or any other governmental entity for the manufacturing
and/or marketing of a product. Consequently, the commencement of the marketing
of any Company product is, in all likelihood, many years away.

      There can be no assurance that CEL-SCI will be successful in obtaining
approvals from any regulatory authority to conduct further clinical trials or to
manufacture and sell its products. The lack of regulatory approval for CEL-SCI's
products will prevent CEL-SCI from generally marketing its products. Delays in
obtaining regulatory approval or the failure to obtain regulatory approval in
one or more countries may have a material adverse impact upon CEL-SCI's
operations.

COMPETITION AND MARKETING

      Many companies, nonprofit organizations and governmental institutions are
conducting research on cytokines. Competition in the development of therapeutic
agents incorporating cytokines is intense. Large, well-established
pharmaceutical companies are engaged in cytokine research and development and
have considerably greater resources than CEL-SCI has to develop products. The
establishment by these large companies of in-house research groups and of joint
research ventures with other entities is already occurring in these areas and
will probably become even more prevalent. In addition, licensing and other
collaborative arrangements between governmental and other nonprofit institutions
and commercial enterprises, as well as the seeking of patent protection of
inventions by nonprofit institutions and researchers, could result in strong
competition for CEL-SCI. Any new developments made by such organizations may
render CEL-SCI's licensed technology and know-how obsolete.

     Several biotechnology companies are producing IL-2-like compounds.  CEL-SCI
believes, however, that it is the only producer of a patented IL-2 product using
a patented  cell-culture  technology with normal human cells.  CEL-SCI  foresees
that   its    principle    competition    will    come   from    producers    of
genetically-engineered  IL-2-like  products.  However,  it is CEL-SCI's  belief,



based upon growing  scientific  evidence,  that its natural IL-2  products  have
advantages  over  the  genetically  engineered,   IL-2-like  products.  Evidence
indicates that  genetically  engineered,  IL-2-like  products,  which lack sugar
molecules  and  typically  are  not  water  soluble,  may be  recognized  by the
immunological  system as a  foreign  agent,  leading  to a  measurable  antibody
build-up and thereby  possibly  voiding their  therapeutic  value.  Furthermore,
CEL-SCI's  research has established that to have optimum  therapeutic value IL-2
should be  administered  not as a single  substance  but rather as an  IL-2-rich
mixture of certain cytokines and other proteins, i.e. as a "cocktail".  If these
differences  prove  to be of  importance,  and if the  therapeutic  value of its
MULTIKINE product is conclusively established,  CEL-SCI believes it will be able
to establish a strong competitive position in a future market.

      CEL-SCI has not established a definitive plan for marketing nor has it
established a price structure for CEL-SCI's saleable products. However, CEL-SCI
intends, if CEL-SCI is in a position to begin commercialization of its products,
to enter into written marketing agreements with various major pharmaceutical
firms with established sales forces. The sales forces in turn would probably
target CEL-SCI's products to cancer centers, physicians and clinics involved in
immunotherapy.

      CEL-SCI may encounter problems, delays and additional expenses in
developing marketing plans with outside firms. In addition, CEL-SCI may
experience other limitations involving the proposed sale of its products, such
as uncertainty of third-party reimbursement. There is no assurance that CEL-SCI
can successfully market any products which they may develop or market them at
competitive prices.

      Some of the clinical trials funded to date by CEL-SCI have not been
approved by the FDA, but rather have been conducted pursuant to approvals
obtained from certain states and foreign countries. Conducting clinical studies
in foreign countries is normal industry practice since these studies can often
be completed in less time and are less expensive than studies conducted in the
U.S. Conducting clinical studies in foreign countries is also beneficial since
CEL-SCI will need the approval from a foreign country prior to the time CEL-SCI
can market any of its drugs in the foreign country. However, since the results
of these clinical trials may not be accepted by the FDA, competitors which are
conducting clinical trials approved by the FDA may have an advantage in that the
products of such competitors are further advanced in the regulatory process than
those of CEL-SCI. CEL-SCI is conducting its trials in compliance with
internationally recognized standards. By following these standards, CEL-SCI
anticipates obtaining acceptance from world regulatory bodies, including the
FDA.

PROPERTIES

      CEL-SCI leases office space at 8229 Boone Blvd., Suite 802, Vienna,
Virginia at a monthly rental of approximately $7,600. CEL-SCI believes this
arrangement is adequate for the conduct of its present business.

      In October 2000, CEL-SCI expanded its fully-equipped laboratory facilities
by 6,200 square feet to 17,900 square feet. This space is leased by CEL-SCI for
approximately $10,450 per month. The laboratory lease expires in 2004, with
extensions available until 2014.



                                   MANAGEMENT

    Name                 Age    Position

Maximilian de Clara      71     Director and President
Geert R. Kersten, Esq.   42     Director, Chief Executive Officer, Secretary
                                and Treasurer
Patricia B. Prichep      49     Senior Vice President of Operations
M. Douglas Winship       51     Senior Vice President of Regulatory Affairs
                                and Quality Assurance
Dr. Eyal Talor           45     Senior Vice President of Research and
                                Manufacturing
Dr. Daniel H. Zimmerman  59     Senior Vice President of Research, Cellular
                                Immunology
Michael Luecke           58     Senior Vice President of Business Development
Alexander G. Esterhazy   56     Director
F. Donald Hudson         67     Director
C. Richard Kinsolving    66     Director

      The directors of CEL-SCI serve in such capacity until the next annual
meeting of CEL-SCI's shareholders and until their successors have been duly
elected and qualified. The officers of CEL-SCI serve at the discretion of
CEL-SCI's directors.

      Mr. Maximilian de Clara, by virtue of his position as an officer and
director of CEL-SCI, may be deemed to be the "parent" and "founder" of CEL-SCI
as those terms are defined under applicable rules and regulations of the
Securities and Exchange Commission.

      The principal occupations of CEL-SCI's officers and directors, during the
past several years, are as follows:

      Maximilian de Clara. Mr. de Clara has been a Director of CEL-SCI since its
inception in March l983, and has been President of CEL-SCI since July l983.
Prior to his affiliation with CEL-SCI, and since at least l978, Mr. de Clara was
involved in the management of his personal investments and personally funding
research in the fields of biotechnology and biomedicine. Mr. de Clara attended
the medical school of the University of Munich from l949 to l955, but left
before he received a medical degree. During the summers of l954 and l955, he
worked as a research assistant at the University of Istanbul in the field of
cancer research. For his efforts and dedication to research and development in
the fight against cancer and AIDS, Mr. de Clara was awarded the "Pour le Merit"
honorary medal of the Austrian Military Order "Merito Navale" as well as the
honor cross of the Austrian Albert Schweitzer Society.

     Geert R. Kersten, Esq. Mr. Kersten was Director of Corporate and Investment
Relations  for CEL-SCI  between  February  1987 and October  1987. In October of
1987, he was appointed  Vice  President of  Operations.  In December  1988,  Mr.
Kersten was appointed  Director of CEL-SCI.  Mr.  Kersten also became  CEL-SCI's
Secretary and Treasurer in 1989. In May 1992,  Mr.  Kersten was appointed  Chief
Operating  Officer and in February  1995, Mr.  Kersten  became  CEL-SCI's  Chief
Executive Officer.  In previous years, Mr. Kersten worked as a financial analyst



with Source Capital, Ltd., an investment advising firm in McLean,  Virginia. Mr.
Kersten is a stepson of Maximilian de Clara, who is the President and a Director
of CEL-SCI.  Mr. Kersten  attended George  Washington  University in Washington,
D.C.  where he earned a B.A.  in  Accounting  and an  M.B.A.  with  emphasis  on
International  Finance.  He also  attended law school at American  University in
Washington, D.C. where he received a Juris Doctor degree.

     Patricia B. Prichep has been CEL-SCI's  Senior Vice President of Operations
since  March  1994.  Between  December  1992 and March  1994,  Ms.  Prichep  was
CEL-SCI's  Director of Operations.  From June 1990 to December 1992, Ms. Prichep
was the Manager of Quality and Productivity for the NASD's  Management,  Systems
and Support  Department.  Between 1982 and 1990,  Ms. Prichep was Vice President
and Operations Manager for Source Capital, Ltd.

     M. Douglas  Winship has been CEL-SCI's  Senior Vice President of Regulatory
Affairs and Quality Assurance since April 1994. Between 1988 and April 1994, Mr.
Winship held various positions with Curative Technologies,  Inc., including Vice
President of Regulatory Affairs and Quality Assurance (1991-1994).

      Eyal Talor, Ph.D. has been CEL-SCI's Senior Vice President of Research and
Manufacturing since March 1994. From October 1993 until March 1994, Dr. Talor
was Director of Research, Manufacturing and Quality Control, as well as the
Director of the Clinical Laboratory, for Chesapeake Biological Laboratories,
Inc. From 1991 to 1993, Dr. Talor was a scientist with SRA Technologies, Inc.,
as well as the director of SRA's Flow Cytometry Laboratory (1991-1993) and
Clinical Laboratory (1992-1993). During 1992 and 1993, Dr. Talor was also the
Regulatory Affairs and Safety Officer For SRA. Since 1987, Dr. Talor has held
various positions with the John Hopkins University, including course coordinator
for the School of Continuing Studies (1989-Present), research associate and
lecturer in the Department of Immunology and Infectious Diseases (1987-1991),
and associate professor (1991-Present).

     Daniel H.  Zimmerman,  Ph.D.  has been  CEL-SCI's  Senior Vice President of
Cellular Immunology since January 1996. Dr. Zimmerman founded CELL-MED, Inc. and
was its president  from  1987-1995.  From 1973 to 1987 Dr.  Zimmerman  served in
various  positions  at  Electronucleonics,   Inc.  including  Scientist,  Senior
Scientist,  Technical Director and Program Manager. From 1969-1973 Dr. Zimmerman
was a Senior Staff Fellow at NIH.

      Michael Luecke joined CEL-SCI as Senior Vice President of Business
Development in June 1998. Mr. Luecke has over 20 years of business experience in
pharmaceutical and biotechnology companies. He has held senior-level business
development/licensing positions with Bristol-Myers, SmithKline and Ciba-Geigy,
as well as several small biopharmaceutical companies.

      Alexander G. Esterhazy has been an independent financial advisor since
November 1997. Between July 1991 and October 1997 Mr. Esterhazy was a senior
partner of Corpofina S.A. Geneva, a firm engaged in mergers, acquisitions and
portfolio management. Between January 1988 and July 1991 Mr. Esterhazy was a
managing director of DG Bank in Switzerland. During this period Mr. Esterhazy
was in charge of the Geneva, Switzerland branch of the DG Bank, founded and



served as vice president of DG Finance (Paris) and was the President and Chief
Executive officer of DG-Bourse, a securities brokerage firm.

     F. Donald  Hudson has been a director of CEL-SCI  since May 19,  2000.  Mr.
Hudson was  previously  a director  of CEL-SCI  between May 1992 and March 1999.
Since October 1995 Mr. Hudson has been a consultant in the biotechnology  field.
From December 1994 to October 1995 Mr. Hudson was President and Chief  Executive
Officer of VIMRx  Pharmaceuticals,  Inc.  (now  Nexell  Corp.).  Mr.  Hudson was
reappointed  as a director on May 19, 2000 in connection  with the settlement of
litigation brought by Mr. Hudson and a former director of CEL-SCI

     C. Richard Kinsolving has been a Director of the Company since April, 2001.
Since  February  1999 Mr.  Kinsolving  has been the Chief  Executive  Officer of
BioPharmacon,  a pharmaceutical  development company.  Between December 1992 and
February 1999 Mr.  Kinsolving  was the  President of Immuno-Rx,  Inc., a company
engaged  in  immuno-pharmaceutical   development.   Between  December  1991  and
September 1995 Mr. Kinsolving was President of Bestechnology,  Inc. a nonmedical
research and development company producing bacterial preparations for industrial
use. Mr.  Kinsolving  received his Ph.D. in Pharmacology  from Emory  University
(1970), his Masters degree in  Physiology/Chemistry  from Vanderbilt  University
(1962),  and his Bachelor's degree in Chemistry from Tennessee Tech.  University
(1957).

     All of  CEL-SCI's  officers  devote  substantially  all of  their  time  to
CEL-SCI's  business.  Messrs.  Esterhazy,  Hudson and Kinsolving,  as directors,
devote only a minimal amount of time to CEL-SCI.

     CEL-SCI has an audit committee and compensation  committee.  The members of
the audit  committee are Geert  Kersten,  Alexander G.  Esterhazy and C. Richard
Kinsolving.  The members of the compensation  committee are Maximilian de Clara,
Alexander Esterhazy and C. Richard Kinsolving.

Executive Compensation

      The following table sets forth in summary form the compensation received
by (i) the Chief Executive Officer of CEL-SCI and (ii) by each other executive
officer of CEL-SCI who received in excess of $100,000 during the fiscal year
ended September 30, 2000.






                                            All
                                           Other                        Other
                                          Annual    Restric-            Com-
                                          Compen-   ted Stock  Options  pensa-
Name and Princi-  Fiscal  Salary   Bonus  sation     Awards    Granted  tion
pal Position       Year    (1)      (2)    (3)        (4)       (5)     (6)
- ----------------  ------  ------   -----  -------   ---------  -------  ------


Maximilian
de Clara,          2000  $345,583     --   $72,945   $550,000   60,000   $  64
President          1999  $335,292     --   $72,945   $435,625  145,000   $  63
                   1998  $315,021     --   $81,709         --  164,000   $  73

Geert R. Kersten,  2000  $303,049     --   $15,349    $10,375   60,000  $4,114
Chief Executive    1999  $268,480     --   $15,154    $10,000  145,000  $4,113
Officer, Secretary 1998  $229,533     --   $15,180    $ 7,500  164,000  $5,310
and Treasurer

Patricia B.
Prichep            2000  $114,430     --    $3,000     $6,998  23,000   $   63
Senior Vice
President          1999  $107,936     --    $3,000     $6,476  79,500   $   63
of Operations

M. Douglas
Winship,           2000  $154,658     --    $2,400     $9,280  20,000   $   64
Senior Vice
President          1999  $146,609     --    $2,400     $8,797  27,500   $   63
of Regulatory
Affairs            1998  $136,918     --    $2,400     $6,240      --   $1,060
and Quality
Assurance

Eyal Talor, Ph.D.  2000  $150,334     --    $3,000     $9,020  50,000   $   63
Senior Vice
President          1999  $139,085     --    $3,000     $8,345  30,000   $   63
of Research and    1998  $130,845     --    $3,000     $5,769  27,000   $  958
Manufacturing

Daniel Zimmerman,  2000  $124,165     --    $3,000     $7,450  20,000   $   64
 Ph.D.,            1999  $114,806     --    $3,000     $6,888  45,000   $   63
Senior Vice
President          1998  $106,360     --    $3,000     $4,882  39,000   $  822
of Cellular
Immunology

Michael Luecke,    2000  $150,000     --        --     $9,000      --   $   64
Senior Vice
President          1999  $150,000     --        --     $8,875      --   $   63
of Business
Development

(1)   The dollar value of base salary (cash and non-cash) received.
(2)   The dollar value of bonus (cash and non-cash) received.
(3)   Any other annual compensation not properly categorized as salary or bonus,
      including perquisites and other personal benefits, securities or property.
      Amounts in the table represent automobile, parking and other
      transportation expenses, plus, in the case of Maximilian de Clara and
      Geert Kersten, director's fees of $8,000.
(4)   During the periods covered by the table, the value of the shares of
      restricted stock issued as compensation for services to the persons listed
      in the table. In the case of Mr. de Clara, the shares were issued in
      consideration for past services rendered to CEL-SCI. In the case of all



      other persons listed in the table, the shares were issued as CEL-SCI's
      contribution on behalf of the named officer to CEL-SCI's 401(k) retirement
      plan.

     As of September 30, 2000,  the number of shares of CEL-SCI's  common stock,
owned by the officers  included in the table above, and the value of such shares
at such date, based upon the market price of CEL-SCI's common stock were:

      Name                          Shares            Value

      Maximilian de Clara               --               --
      Geert R. Kersten             137,088         $300,223
      Patricia B. Prichep           12,791        $  28,012
      M. Douglas Winship             9,116        $  19,964
      Eyal Talor, Ph.D.             10,182        $  22,299
      Daniel Zimmerman, Ph.D.       27,207        $  59,583
      Michael Luecke                 8,209        $  17,978

     Dividends  may be paid on shares of  restricted  stock  owned by  CEL-SCI's
officers and directors, although CEL-SCI has no plans to pay dividends.

(5)   The shares of Common Stock to be received upon the exercise of all stock
      options granted during the periods covered by the Table. Includes certain
      options issued in connection with CEL-SCI's Salary Reduction Plans as well
      as certain options purchased from CEL-SCI. See "Options Granted During
      Fiscal Year Ending September 30, 2000" below.
(6)   All other compensation received that CEL-SCI could not properly report in
      any other column of the Table including annual Company contributions or
      other allocations to vested and unvested defined contribution plans, and
      the dollar value of any insurance premiums paid by, or on behalf of,
      CEL-SCI with respect to term life insurance for the benefit of the named
      executive officer, and the full dollar value of the remainder of the
      premiums paid by, or on behalf of, CEL-SCI. Amounts in the table represent
      life insurance premiums.

Long Term Incentive Plans - Awards in Last Fiscal Year

      None.

Employee Pension, Profit Sharing or Other Retirement Plans

      During 1993 CEL-SCI implemented a defined contribution retirement plan,
qualifying under Section 401(k) of the Internal Revenue Code and covering
substantially all CEL-SCI's employees. Prior to January 1, 1998 CEL-SCI's
contribution was equal to the lesser of 3% of each employee's salary, or 50% of
the employee's contribution. Effective January 1, 1998 the plan was amended such
that CEL-SCI's contribution is now made in shares of CEL-SCI's common stock as
opposed to cash. Each participant's contribution is matched by CEL-SCI with
shares of common stock which have a value equal to 100% of the participant's



contribution, not to exceed the lesser of $1,000 or 6% of the participant's
total compensation. CEL-SCI's contribution of common stock is valued each
quarter based upon the closing price of CEL-SCI's common stock. The fiscal 2000
expenses for this plan were $102,559. Other than the 401(k) Plan, CEL-SCI does
not have a defined benefit, pension plan, profit sharing or other retirement
plan.

Compensation of Directors

      Standard Arrangements. CEL-SCI currently pays its directors $2,000 per
quarter, plus expenses. CEL-SCI has no standard arrangement pursuant to which
directors of CEL-SCI are compensated for any services provided as a director or
for committee participation or special assignments.

     Other  Arrangements.  CEL-SCI has from time to time granted  options to its
outside directors. See Stock Options below for additional information concerning
options granted to CEL-SCI's directors.

Employment Contracts Effective April 12, 1999, CEL-SCI entered into a three-year
employment agreement with Mr. de Clara. The employment agreement provides that
CEL-SCI will pay Mr. de Clara an annual salary of $363,000 during the term of
the agreement. In the event that there is a material reduction in Mr. de Clara's
authority, duties or activities, or in the event there is a change in the
control of CEL-SCI, then the agreement allows Mr. de Clara to resign from his
position at CEL-SCI and receive a lump-sum payment from CEL-SCI equal to 18
months salary. For purposes of the employment agreement, a change in the control
of CEL-SCI means the sale of more than 50% of the outstanding shares of
CEL-SCI's Common Stock, or a change in a majority of CEL-SCI's directors.

      Effective August 1, 2000, CEL-SCI entered into a three-year employment
agreement with Mr. Kersten. The employment agreement provides that during the
term of the employment agreement CEL-SCI will pay Mr. Kersten an annual salary
of $336,132, subject to the minimum annual increases of 5% per year. In the
event there is a change in the control of CEL-SCI, the agreement allows Mr.
Kersten to resign from his position at CEL-SCI and receive a lump-sum payment
from CEL-SCI equal to 24 months salary. For purposes of the employment agreement
a change in the control of CEL-SCI means: (1) the merger of CEL-SCI with another
entity if after such merger the shareholders of CEL-SCI do not own at least 50%
of voting capital stock of the surviving corporation; (2) the sale of
substantially all of the assets of CEL-SCI; (3) the acquisition by any person of
more than 50% of CEL-SCI's common stock; or (4) a change in a majority of
CEL-SCI's directors which has not been approved by the incumbent directors.

Compensation Committee Interlocks and Insider Participation

     CEL-SCI  has  a  compensation  committee  comprised  of  all  of  CEL-SCI's
directors,  with the exception of Mr.  Kersten.  During the year ended September



30, 2000, Mr. de Clara was the only officer  participating  in  deliberations of
CEL-SCI's compensation committee concerning executive officer compensation.

      During the year ended September 30, 2000, no director of CEL-SCI was also
an executive officer of another entity, which had an executive officer of
CEL-SCI serving as a director of such entity or as a member of the compensation
committee of such entity.

Stock Options

      The following tables set forth information concerning the options granted
during the fiscal year ended September 30, 2000, to the persons named below, and
the fiscal year-end value of all unexercised options (regardless of when
granted) held by these persons.

                Options Granted During Fiscal Year Ending September 30, 2000
                ------------------------------------------------------------
                   Individual Grants
- -------------------------------------------------


                                                                      

                                                                        Potential Realizable
                               % of Total                                Value at Assumed
                                 Options                               Annual Rates of Stock
                                Granted to    Exercise                   Price Appreciation
                   Options      Employees in  Price Per  Expiration     for Option Term (1)
Name               Granted (#)  Fiscal Year    Share       Date           5%            10%
- ----               -----------  ------------  ---------  ----------      ----          ----

Maximilian de Clara   60,000        15%         $3.06      4/19/10      $115,200     $292,611

Geert R. Kersten      60,000        15%         $3.06      4/19/10      $115,200     $292,611

Patricia B. Prichep   23,000       5.8%         $4.00      2/02/10       $57,858     $146,510

Eyal Talor, Ph.D.     50,000      12.6%         $2.56     11/27/09       $80,000     $204,000

M. Douglas Winship    20,000         5%         $5.37      4/03/10       $67,543     $171,160

Daniel Zimmerman,
 Ph.D.                20,000         5%         $4.00      2/02/10       $50,300     $127,400




(1)  The potential  realizable  value of the options shown in the table assuming
     the market price of CEL-SCI's  Common Stock  appreciates  in value from the
     date of the grant to the end of the option term at 5% or 10%.





                   Option Exercises and Year-End Option Values

                                                                 Value (in $) of
                                                                  Unexercised
                                                Number of         In-the-Money
                                               Unexercised     Options at Fiscal
                          Shares               Options (3)        Year-End (4)
                                               ------------    -----------------
                     Acquired On     Value       Exercisable/      Exercisable/
Name                 Exercise (1) Realized (2) Unexercisable     Unexercisable
- ----                 ------------ ------------ -------------   -----------------

Maximilian de Clara   373,667     $1,436,548   295,000/109,999      25,916/4,333
Geert R. Kersten       50,750       $137,310  1,020,001/109,999     25,916/4,333
Patricia Prichep       23,000        $89,900   190,834/38,666       12,525/1,300
M. Douglas Winship      2,000         $4,510    82,500/30,000        3,775/1,300
Eyal Talor             91,334       $274,626    70,833/18,333        3,366/1,733
Daniel Zimmerman       24,000       $141,120    91,000/35,000        8,150/1,300
Michael Luecke         10,000        $44,425    40,000/50,000             --/--

(1)  The number of shares received upon exercise of options during the fiscal
     year ended September 30, 2000.

(2)  With respect to options exercised during CEL-SCI's fiscal year ended
     September 30, 2000, the dollar value of the difference between the option
     exercise price and the market value of the option shares purchased on the
     date of the exercise of the options.

(3)  The total number of unexercised options held as of September 30, 2000,
     separated between those options that were exercisable and those options
     that were not exercisable.

(4)  For all unexercised options held as of September 30, 2000, the market value
     of the stock underlying those options as of September 30, 2000.

Stock Option and Bonus Plans

      CEL-SCI has Incentive Stock Option Plans, Non-Qualified Stock Option Plans
and Stock Bonus Plans. A summary description of these Plans follows. In some
cases these Plans are collectively referred to as the "Plans".

      Incentive Stock Option Plan. The Incentive Stock Option Plans collectively
authorize the issuance of up to 2,100,000 shares of CEL-SCI's Common Stock to
persons that exercise options granted pursuant to the Plan. Only Company
employees may be granted options pursuant to the Incentive Stock Option Plan.

      To be classified as incentive stock options under the Internal Revenue
Code, options granted pursuant to the Plans must be exercised prior to the
following dates:

   (a)      The expiration of three months after the date on which an option
            holder's employment by CEL-SCI is terminated (except if such
            termination is due to death or permanent and total disability);




   (b)      The expiration of 12 months after the date on which an option
            holder's employment by CEL-SCI is terminated, if such termination is
            due to the Employee's permanent and total disability;

   (c)      In the event of an option holder's death while in the employ of
            CEL-SCI, his executors or administrators may exercise, within three
            months following the date of his death, the option as to any of the
            shares not previously exercised;

      The total fair market value of the shares of Common Stock (determined at
the time of the grant of the option) for which any employee may be granted
options which are first exercisable in any calendar year may not exceed
$100,000.

      Options may not be exercised until one year following the date of grant.
Options granted to an employee then owning more than 10% of the Common Stock of
CEL-SCI may not be exercisable by its terms after five years from the date of
grant. Any other option granted pursuant to the Plan may not be exercisable by
its terms after ten years from the date of grant.

      The purchase price per share of Common Stock purchasable under an option
is determined by the Committee but cannot be less than the fair market value of
the Common Stock on the date of the grant of the option (or 110% of the fair
market value in the case of a person owning more than 10% of CEL-SCI's
outstanding shares).

      Non-Qualified Stock Option Plan. The Non-Qualified Stock Option Plans
collectively authorize the issuance of up to 3,760,000 shares of CEL-SCI's
Common Stock to persons that exercise options granted pursuant to the Plans.
CEL-SCI's employees, directors, officers, consultants and advisors are eligible
to be granted options pursuant to the Plans, provided however that bona fide
services must be rendered by such consultants or advisors and such services must
not be in connection with the offer or sale of securities in a capital-raising
transaction. The option exercise price is determined by the Committee but cannot
be less than the market price of CEL-SCI's Common Stock on the date the option
is granted.

      Stock Bonus Plan. Up to 1,040,000 shares of Common Stock may be granted
under the Stock Bonus Plan. Such shares may consist, in whole or in part, of
authorized but unissued shares, or treasury shares. Under the Stock Bonus Plan,
CEL-SCI's employees, directors, officers, consultants and advisors are eligible
to receive a grant of CEL-SCI's shares, provided however that bona fide services
must be rendered by consultants or advisors and such services must not be in
connection with the offer or sale of securities in a capital-raising
transaction.

      Other Information Regarding the Plans. The Plans are administered by
CEL-SCI's Compensation Committee ("the Committee"), each member of which is a
director of CEL-SCI. The members of the Committee were selected by CEL-SCI's
Board of Directors and serve for a one-year tenure and until their successors
are elected. A member of the Committee may be removed at any time by action of
the Board of Directors. Any vacancies which may occur on the Committee will be
filled by the Board of Directors. The Committee is vested with the authority to
interpret the provisions of the Plans and supervise the administration of the



Plans. In addition, the Committee is empowered to select those persons to whom
shares or options are to be granted, to determine the number of shares subject
to each grant of a stock bonus or an option and to determine when, and upon what
conditions, shares or options granted under the Plans will vest or otherwise be
subject to forfeiture and cancellation.

      In the discretion of the Committee, any option granted pursuant to the
Plans may include installment exercise terms such that the option becomes fully
exercisable in a series of cumulating portions. The Committee may also
accelerate the date upon which any option (or any part of any options) is first
exercisable. Any shares issued pursuant to the Stock Bonus Plan and any options
granted pursuant to the Incentive Stock Option Plan or the Non-Qualified Stock
Option Plan will be forfeited if the "vesting" schedule established by the
Committee administering the Plan at the time of the grant is not met. For this
purpose, vesting means the period during which the employee must remain an
employee of CEL-SCI or the period of time a non-employee must provide services
to CEL-SCI. At the time an employee ceases working for CEL-SCI (or at the time a
non-employee ceases to perform services for CEL-SCI), any shares or options not
fully vested will be forfeited and cancelled. At the discretion of the Committee
payment for the shares of Common Stock underlying options may be paid through
the delivery of shares of CEL-SCI's Common Stock having an aggregate fair market
value equal to the option price, provided such shares have been owned by the
option holder for at least one year prior to such exercise. A combination of
cash and shares of Common Stock may also be permitted at the discretion of the
Committee.

      Options are generally non-transferable except upon death of the option
holder. Shares issued pursuant to the Stock Bonus Plan will generally not be
transferable until the person receiving the shares satisfies the vesting
requirements imposed by the Committee when the shares were issued.

      The Board of Directors of CEL-SCI may at any time, and from time to time,
amend, terminate, or suspend one or more of the Plans in any manner they deem
appropriate, provided that such amendment, termination or suspension will not
adversely affect rights or obligations with respect to shares or options
previously granted. The Board of Directors may not, without shareholder
approval: make any amendment which would materially modify the eligibility
requirements for the Plans; increase or decrease the total number of shares of
Common Stock which may be issued pursuant to the Plans except in the case of a
reclassification of CEL-SCI's capital stock or a consolidation or merger of
CEL-SCI; reduce the minimum option price per share; extend the period for
granting options; or materially increase in any other way the benefits accruing
to employees who are eligible to participate in the Plans.

      Summary. The following sets forth certain information, as of March 31,
2001, concerning the stock options and stock bonuses granted by CEL-SCI. Each
option represents the right to purchase one share of CEL-SCI's Common Stock.






                             Total        Shares
                            Shares      Reserved for   Shares       Remaining
                            Reserved    Outstanding   Issued as  Options/Shares
Name of Plan               Under Plans   Options     Stock Bonus   Under Plans
- ------------               -----------  -----------  -----------  ------------

Incentive Stock Option
 Plans                       2,100,000   1,170,100       N/A         843,315

Non-Qualified Stock Option
    Plans                    3,760,000   2,323,139       N/A         359,400

Stock Bonus Plans            1,040,000         N/A    515,858        524,142

     Of the shares issued pursuant to CEL-SCI's Stock Bonus Plans 112,454 shares
were issued as part of CEL-SCI's contribution to its 401(k) plan.

     During the year ended  September 30, 1999 CEL-SCI  issued 200,000 shares of
its common  stock to Mr. de Clara for past  services  provided  to  CEL-SCI.  In
January 2000 CEL-SCI issued Mr. de Clara an additional  200,000 shares of common
stock for past services provided to CEL-SCI.

                             PRINCIPAL SHAREHOLDERS

      The following table sets forth, as of March 31, 2001, information with
respect to the only persons owning beneficially 5% or more of CEL-SCI's common
stock and the number and percentage of outstanding shares owned by each director
and officer of CEL-SCI and by all the officers and directors as a group. Unless
otherwise indicated, each owner has sole voting and investment powers over his
shares of common stock.

Name and Address                   Number of Shares  (1)   Percent of Class (3)
- ----------------                   -----------------       ----------------

Maximilian de Clara                  348,333                      *
Bergstrasse 79
6078 Lungern,
Obwalden, Switzerland

Geert R. Kersten                    1,213,715                  5.7%
8229 Boone Blvd., Suite 802
Vienna, VA  22182

Patricia B. Prichep                   218,647                     *
8229 Boone Blvd., Suite 802
Vienna, VA  22182

M. Douglas Winship                    106,340                     *
8229 Boone Blvd., Suite 802
Vienna, VA  22182



Name and Address                   Number of Shares  (1)   Percent of Class (3)
- ----------------                   -----------------       ----------------

Eyal Talor, Ph.D.                      84,300                     *
8229 Boone Blvd., Suite 802
Vienna, VA  22182

Daniel H. Zimmerman, Ph.D.            137,405                     *
8229 Boone Blvd., Suite 802
Vienna, VA  22182

Michael Luecke                         86,032                     *
8229 Boone Blvd., Suite 802
Vienna, VA  22182

Alexander G. Esterhazy                 25,000                     *
20 Chemin du Pre-Poiset
CH- 1253 Vandoeuvres
Geneve, Switzerland

F. Donald Hudson                      137,000                     *
40 Moorings Road
Marion, MA  02738

C. Richard Kinsolving                      --                    --
5414 61st Street East
Bradenton, FL 34203

All Officers and Directors          2,356,77211.2%as a Group (10 persons)
*    Less than 1%

(1)  Includes shares issuable prior to June 30, 2001 upon the exercise of
     options or warrants granted to the following persons:

                                          Options or Warrants Exercisable
      Name                                     Prior to June 30, 2001
      ----                                -------------------------------

      Maximilian de Clara                          348,333
      Geert R. Kersten                           1,073,334
      Patricia B. Prichep                          203,501
      M. Douglas Winship                            94,167
      Eyal Talor, Ph.D.                             70,833
      Daniel H. Zimmerman, Ph.D.                   107,667
      Michael Luecke                                75,000
      Alexander G. Esterhazy                        25,000



      F. Donald Hudson                             137,000
      C. Richard Kinsolving                             --

(2)  Amount includes shares held in trust for the benefit of Mr. Kersten's minor
     children. Geert R. Kersten is the stepson of Maximilian de Clara.

(3)  Amount includes shares referred to in (1) above but excludes shares which
     may be issued upon the exercise or conversion of other options, warrants
     and other convertible securities previously issued by CEL-SCI.

                         EQUITY LINE OF CREDIT AGREEMENT

Overview

      On April 11, 2001, CEL-SCI entered into an equity line of credit agreement
with Paul Revere Capital Partners, Ltd. in order to establish a possible source
of funding for the development of CEL-SCI's technologies. The equity line of
credit agreement establishes what is sometimes also referred to as an equity
drawdown facility.

      Under the equity line of credit agreement, Paul Revere Capital Partners,
Ltd. has agreed to provide CEL-SCI with up to $10,000,000 of funding during the
twenty-four month period following the date of this prospectus. During this
twenty-four month period, CEL-SCI may request a drawdown under the equity line
of credit by selling shares of its common stock to Paul Revere Capital Partners
and Paul Revere Capital Partners will be obligated to purchase the shares.
CEL-SCI may request a drawdown once every 22 trading days, although CEL-SCI is
under no obligation to request any drawdowns under the equity line of credit.

      During the 22 trading days following a drawdown request, CEL-SCI will
calculate the amount of shares it will sell to Paul Revere Capital Partners and
the purchase price per share. The purchase price per share of common stock will
based on the daily volume weighted average price of CEL-SCI's common stock
during each of the 22 trading days immediately following the drawdown date, less
a discount of 11%.

      CEL-SCI may request a drawdown by faxing a drawdown notice to Paul Revere
Capital Partners, Ltd., stating the amount of the drawdown and the lowest daily
volume weighted average price, if any, at which CEL-SCI is willing to sell the
shares. The lowest volume weighted average price will be set by CEL-SCI's Chief
Executive Officer in his sole and absolute discretion.

Calculation of Drawdown Amount, Purchase Price and Number of Shares Sold

      The minimum amount CEL-SCI can draw down at any one time is $100,000.
Without the consent of Paul Revere Capital Partners, the maximum amount CEL-SCI
can draw down at any one time is the lesser of $2,000,000 or the amount equal
to:




o    4.5% of the weighted average price of CEL-SCI's common stock for the ninety
     calendar day period prior to the date of the drawdown request
o    multiplied  by the total trading  volume of CEL-SCI's  common stock for the
     ninety calendar day period prior to the date of the drawdown request.

      On the day following the delivery of the drawdown notice, a valuation
period of 22 trading days will start:

o        On each trading day during the valuation period where the daily volume
         weighted average price of CEL-SCI's common stock on the American Stock
         Exchange exceeds the minimum price, if any, specified by CEL-SCI in the
         drawdown notice, the purchase price will equal 89% of the volume
         weighted average price on that day.

o        On each of the 22 trading days during the valuation period, the number
         of shares to be sold to Paul Revere Capital Partners will be determined
         by dividing 1/22 of the drawdown amount by the purchase price on each
         trading day.

o        If the volume weighted average price for CEL-SCI's common stock on any
         trading day during the 22 trading day calculation period is below the
         minimum price, then Paul Revere Capital Partners will not purchase any
         shares on that day, and the drawdown amount will be reduced by 1/22.


      Using the formula described above, if CEL-SCI had requested a drawdown on
April 12, 2001, the maximum amount CEL-SCI could draw down during the subsequent
22 trading days would have been $365,304. Based upon the volume weighted average
of CEL-SCI's common stock during these 22 trading days, CEL-SCI would have sold
273,635 shares of its common stock to Paul Revere Capital Partners and would
have received proceeds from the sale of these shares equal to $365,304.

      If CEL-SCI sets a minimum price which is too high and CEL-SCI's stock
price does not consistently meet that level during the 22 trading days after its
drawdown request, the amount CEL-SCI can draw and the number of shares CEL-SCI
will sell to Paul Revere Capital Partners will be reduced. On the other hand, if
CEL-SCI sets a minimum price which is too low and its stock price falls
significantly but stays above the minimum price, CEL-SCI will have to issue a
greater number of shares to Paul Revere Capital Partners based on the reduced
market price.

Payment for Shares Issued

      The shares purchased on the first 11 trading days will be issued and paid
for on the 13th trading day following the drawdown request. The shares purchased
on the 12th through the 22nd trading days will be issued and paid for on the
24th trading day following the drawdown request.

      Upon closing of the equity line of credit Agreement, CEL-SCI paid $35,000
to Paul Revere Capital Partners legal counsel, Epstein Becker & Green P.C., to
cover its legal and administrative expenses.




Grant of Warrants

      As consideration for extending the equity line of credit, CEL-SCI granted
Paul Revere Capital Partners warrants to purchase 200,800 shares of common stock
at any time prior to April 11, 2004 at a price of $1.64 per share. Paul Revere
Capital Partners is not obligated to exercise any warrants.

      CEL-SCI believes that the fair value of these warrants using customary
pricing models is approximately $20,000. The fair value of these warrants will
be reflected in CEL-SCI's financial statements and recorded as an expense during
the quarter ended June 30, 2001.

Restrictions on Future Financings

      During the term of the equity line of credit agreement, CEL-SCI may not
raise capital through any other equity line of credit arrangement.

Termination of the Equity Line of Credit Agreement

      The Equity Line of Credit Agreement will terminated if:

o    any event,  which has not been  corrected  within 30 days,  has taken place
     which  has  any  material  adverse  effect  on the  business  or  financial
     condition of CEL-SCI or which  prohibits or interferes  with the ability of
     CEL-SCI to perform any of its material obligations under the equity line of
     credit agreement,
o    CEL-SCI's common stock is de-listed from the American Stock Exchange unless
     the de-listing is in connection  with CEL-SCI's  subsequent  listing of its
     common stock on the NASDAQ National  Market,  the NASDAQ SmallCap Market or
     the New York Stock Exchange, or
o    CEL-SCI  files  for  protection   from  its  creditors  under  the  Federal
     Bankruptcy laws.

      CEL-SCI may terminate the equity line of credit if Paul Revere Capital
Partners fails to honor more than one drawdown notice.

Indemnification

      Paul Revere Capital Partners is entitled to customary indemnification from
CEL-SCI for any losses or liabilities it suffers based upon material
misstatements or omissions from the registration statement and this prospectus,
except as they relate to information Paul Revere Capital Partners supplied to
CEL-SCI for inclusion in the registration statement and prospectus.

                               SELLING SHAREHOLDER

     This prospectus  relates to sales of CEL-SCI's  common stock by Paul Revere
Capital Partners.  Paul Revere Capital Partners will receive shares of CEL-SCI's
common stock under an equity line of credit  agreement and up to 200,800  shares



of common stock upon the exercise of warrants.  Paul Revere Capital  Partners is
sometimes referred to in this prospectus as the selling shareholder.

      CEL-SCI will not receive any proceeds from the sale of the shares by Paul
Revere Capital Partners. Paul Revere Capital Partners may resell the shares it
acquires by means of this prospectus from time to time in the public market. The
costs of registering the shares offered by Paul Revere Capital Partners is being
paid by CEL-SCI. Paul Revere Capital Partners will pay all other costs of the
sale of the shares offered by them.

    The following table shows the shares which are being offered for sale by
Paul Revere Capital Partners.

                                           Shares                       Share
                              Shares   Issuable Upon  Shares to Be    Ownership
                            Presently  the Exercise   Sold in this      After
Name                          Owned     of Warrants     Offering      Offering
- ----                        ---------  -------------  ------------   ----------

Paul Revere Capital Partners     (1)     200,800             (1)         --

(1) The number of shares owned by Paul Revere Capital Partners will vary from
time-to-time and will depend upon the number of shares purchased from CEL-SCI
pursuant to the terms of the Equity Line Agreement.

Manner of Sale.

      The shares of common stock owned, or which may be acquired, by Paul Revere
Capital Partners may be offered and sold by means of this prospectus from time
to time as market conditions permit in the over-the-counter market, or
otherwise, at prices and terms then prevailing or at prices related to the
then-current market price, or in negotiated transactions. These shares may be
sold by one or more of the following methods, without limitation:

o    a block trade in which a broker or dealer so engaged  will  attempt to sell
     the shares as agent but may  position  and resell a portion of the block as
     principal to facilitate the transaction;
o    purchases by a broker or dealer as  principal  and resale by such broker or
     dealer for its account pursuant to this prospectus;
o    ordinary  brokerage  transactions  and  transactions  in which  the  broker
     solicits purchasers; and
o    face-to-face   transactions   between  sellers  and  purchasers  without  a
     broker/dealer.

      In effecting sales, brokers or dealers engaged by Paul Revere Capital
Partners may arrange for other brokers or dealers to participate. Such brokers
or dealers may receive commissions or discounts from Paul Revere Capital
Partners in amounts to be negotiated.

      Paul Revere Capital Partners is an "underwriter" and any broker/dealers
who act in connection with the sale of the shares by means of this prospectus
may be deemed to be "underwriters" within the meaning of ss.2(11) of the



Securities Acts of 1933, and any commissions received by them and profit on any
resale of the shares as principal might be deemed to be underwriting discounts
and commissions under the Securities Act. CEL-SCI has agreed to indemnify Paul
Revere Capital Partners and any securities broker/dealers who may be deemed to
be underwriters against certain liabilities, including liabilities under the
Securities Act as underwriters or otherwise.

      CEL-SCI has advised Paul Revere Capital Partners that it and any
securities broker/dealers or others who may be deemed to be statutory
underwriters will be subject to the prospectus delivery requirements under the
Securities Act of 1933. CEL-SCI has also advised Paul Revere Capital Partners,
Ltd. that in the event of a "distribution" of its shares Paul Revere Capital
Partners, any "affiliated purchasers", and any broker/dealer or other person who
participates in such distribution may be subject to Rule 102 under the
Securities Exchange Act of 1934 ("1934 Act") until their participation in that
distribution is completed. Rule 102 makes it unlawful for any person who is
participating in a distribution to bid for or purchase stock of the same class
as is the subject of the distribution. A "distribution" is defined in Rule 102
as an offering of securities "that is distinguished from ordinary trading
transactions by the magnitude of the offering and the presence of special
selling efforts and selling methods". CEL-SCI has also advised Paul Revere
Capital Partners, Ltd. that Rule 101 under the 1934 Act prohibits any
"stabilizing bid" or "stabilizing purchase" for the purpose of pegging, fixing
or stabilizing the price of the common stock in connection with this offering.

Grant of Registration Rights

      CEL-SCI granted registration rights to Paul Revere Capital Partners, Ltd.
to enable it to sell the common stock it may acquire under the equity line of
credit agreement or upon the exercise of the warrants. Notwithstanding these
registration rights, CEL-SCI has no obligation:

o    to assist or  cooperate  with Paul  Revere  Capital  Partners,  Ltd. in the
     offering or disposition of their shares;

o    to obtain a commitment from an underwriter  relative to the sale of any the
     shares; or

o    to include the shares within any underwritten offering.

      The registration rights agreement with Paul Revere Capital Partners, Ltd.
permits CEL-SCI to restrict the resale of the shares Paul Revere Capital
Partners, Ltd. has purchased under the equity line of credit agreement for a
period of time sufficient to permit CEL-SCI to amend or supplement this
prospectus to include material information. If CEL-SCI restricts the ability
Paul Revere Capital Partners, Ltd. to resell shares at any time during the
thirty-two trading days following the delivery of a drawdown notice, and
CEL-SCI's stock price declines during the restriction period, then, in order to
compensate Paul Revere Capital Partners, Ltd. for its inability to sell shares
during the restriction period, CEL-SCI will be required to pay Paul Revere
Capital Partners, Ltd. an amount determined by multiplying:




o    the number of shares Paul Revere  Capital  Partners,  Ltd. is  committed to
     purchase following the delivery of the drawdown notice, and

o    the  difference  between  the  highest  daily  weighted  average  price  of
     CEL-SCI's  common  stock  during the  restriction  period and the  weighted
     average  price of CEL-SCI's  common stock on the day after the  restriction
     period ends.

                            DESCRIPTION OF SECURITIES

Common Stock

      CEL-SCI is authorized to issue 100,000,000 shares of common stock, (the
"common stock"). Holders of common stock are each entitled to cast one vote for
each share held of record on all matters presented to shareholders. Cumulative
voting is not allowed; hence, the holders of a majority of the outstanding
common stock can elect all directors.

      Holders of common stock are entitled to receive such dividends as may be
declared by the Board of Directors out of funds legally available therefor and,
in the event of liquidation, to share pro rata in any distribution of CEL-SCI's
assets after payment of liabilities. The board is not obligated to declare a
dividend. It is not anticipated that dividends will be paid in the foreseeable
future.

      Holders of common stock do not have preemptive rights to subscribe to
additional shares if issued by CEL-SCI. There are no conversion, redemption,
sinking fund or similar provisions regarding the common stock . All of the
outstanding shares of Common stock are fully paid and non-assessable.

Preferred Stock

      CEL-SCI is authorized to issue up to 200,000 shares of preferred stock.
CEL-SCI's Articles of Incorporation provide that the Board of Directors has the
authority to divide the preferred stock into series and, within the limitations
provided by Colorado statute, to fix by resolution the voting power,
designations, preferences, and relative participation, special rights, and the
qualifications, limitations or restrictions of the shares of any series so
established. As the Board of Directors has authority to establish the terms of,
and to issue, the preferred stock without shareholder approval, the preferred
stock could be issued to defend against any attempted takeover of CEL-SCI.

      No shares of preferred stock were outstanding as of March 31, 2001.

Transfer Agent

     American Securities Transfer,  Inc., of Denver,  Colorado,  is the transfer
agent for CEL-SCI's common stock.




                                     EXPERTS

      The consolidated financial statements of CEL-SCI Corporation as of
September 30, 2000 and 1999, and for each of the three years in the period ended
September 30, 1999 included as part of this prospectus, have been audited by
Deloitte & Touche LLP, independent auditors, as stated in their report and have
been so included in reliance upon the report of such firm given upon their
authority as experts in accounting and auditing.

                                 INDEMNIFICATION

      CEL-SCI's bylaws authorize indemnification of a director, officer,
employee or agent of CEL-SCI against expenses incurred by him in connection with
any action, suit, or proceeding to which he is named a party by reason of his
having acted or served in such capacity, except for liabilities arising from his
own misconduct or negligence in performance of his duty. In addition, even a
director, officer, employee, or agent of CEL-SCI who was found liable for
misconduct or negligence in the performance of his duty may obtain such
indemnification if, in view of all the circumstances in the case, a court of
competent jurisdiction determines such person is fairly and reasonably entitled
to indemnification. Insofar as indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to directors, officers, or persons
controlling CEL-SCI pursuant to the foregoing provisions, CEL-SCI has been
informed that in the opinion of the Securities and Exchange Commission, such
indemnification is against public policy as expressed in the Act and is
therefore unenforceable.

                             ADDITIONAL INFORMATION

      CEL-SCI is subject to the requirements of the Securities Exchange Act of
l934 and is required to file reports, proxy statements and other information
with the Securities and Exchange Commission. Copies of any such reports, proxy
statements and other information filed by CEL-SCI can be read and copied at the
Commission's Public Reference Room at 450 Fifth Street, N.W., Washington, D.C.,
20549. The public may obtain information on the operation of the Public
Reference Room by calling the Commission at 1-800-SEC-0330. The Commission
maintains an Internet site that contains reports, proxy and information
statements, and other information regarding CEL-SCI. The address of that site is
http://www.sec.gov.

      CEL-SCI has filed with the Securities and Exchange Commission a
Registration Statement under the Securities Act of l933, as amended, with
respect to the securities offered by this prospectus. This prospectus does not
contain all of the information set forth in the Registration Statement. For
further information with respect to CEL-SCI and such securities, reference is
made to the Registration Statement and to the exhibits filed with the
Registration Statement. Statements contained in this prospectus as to the
contents of any contract or other documents are summaries which are not
necessarily complete, and in each instance reference is made to the copy of such
contract or other document filed as an exhibit to the Registration Statement,
each such statement being qualified in all respects by such reference. The
Registration Statement and related exhibits may also be examined at the
Commission's internet site.




CEL-SCI CORPORATION

Consolidated Financial Statements for the Years
Ended September 30, 2000, 1999, and 1998,
and Independent Auditors' Report





CEL-SCI CORPORATION

TABLE OF CONTENTS
- --------------------------------------------------------------------------------

                                                                       Page

INDEPENDENT AUDITORS' REPORT                                            F-1

CONSOLIDATED  FINANCIAL STATEMENTS FOR THE
YEARS ENDED SEPTEMBER 30, 2000, 1999, AND 1998:

  Consolidated Balance Sheets                                           F-2

  Consolidated Statements of Operations                                 F-3

  Consolidated Statements of Comprehensive Loss                         F-4

  Consolidated Statements of Stockholders' Equity                       F-5

  Consolidated Statements of Cash Flows                              F-6 - F-7

  Notes to Consolidated Financial Statements                         F-8 - F-17

















INDEPENDENT AUDITORS' REPORT


To the Board of Directors and Shareholders of CEL-SCI Corporation:

We  have  audited  the  accompanying  consolidated  balance  sheets  of  CEL-SCI
Corporation  and  subsidiaries  (the Company) as of September 30, 2000 and 1999,
and the related  consolidated  statements  of  operations,  comprehensive  loss,
stockholders'  equity,  and cash flows for each of the three years in the period
ended September 30, 2000. These financial  statements are the  responsibility of
the Company's  management.  Our responsibility is to express an opinion on these
financial statements based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the  United  States of  America.  Those  standards  require  that we plan and
perform the audit to obtain  reasonable  assurance  about  whether the financial
statements are free of material misstatement.  An audit includes examining, on a
test basis,  evidence  supporting  the amounts and  disclosures in the financial
statements.  An audit also includes assessing the accounting principles used and
significant  estimates  made by  management,  as well as evaluating  the overall
financial  statement  presentation.   We  believe  that  our  audits  provide  a
reasonable basis for our opinion.

In our opinion, the consolidated  financial statements referred to above present
fairly, in all material respects,  the financial position of CEL-SCI Corporation
and its subsidiaries as of September 30, 2000 and 1999, and the results of their
operations  and their cash flows for each of the three years in the period ended
September 30, 2000, in conformity with generally accepted accounting  principles
in the United States of America.


Deloitte & Touche LLP

McLean, Virginia
November 17, 2000






CEL-SCI CORPORATION

CONSOLIDATED BALANCE SHEETS
SEPTEMBER 30, 2000 AND 1999
- --------------------------------------------------------------------------------

ASSETS                                                     2000          1999

CURRENT ASSETS:
    Cash and cash equivalents                           $6,909,263    $2,747,644
    Investment securities available for sale             3,760,922     3,191,491
    Interest and other receivables                          39,252        62,825
    Prepaid expenses                                     1,838,376       514,572
    Advances to officer/shareholder and employees              728        69,448

                      Total current assets              12,548,541     6,585,980

RESEARCH AND OFFICE EQUIPMENT - Less accumulated
    depreciation of $1,721,336 and $1,563,586              594,919       468,627

DEPOSITS                                                   139,828        14,828

PATENT COSTS - Less accumulated amortization
    of $574,362 and $511,118                               525,594       490,337
                                                        ----------     ---------

                                                       $13,808,882    $7,559,772
                                                       ===========    ==========

LIABILITIES AND STOCKHOLDERS' EQUITY

CURRENT LIABILITIES:
    Accounts payable and accrued expenses               $  822,601     $ 433,265
                                                        ----------     ---------

                      Total current liabilities            822,601       433,265

DEFERRED RENT                                               24,822        28,321
                                                        ----------     ---------

                     Total liabilities                     847,423       461,586
                                                        ----------     ---------

STOCKHOLDERS' EQUITY:
    Common stock, $.01 par value - authorized,
100,000,000 shares;
        issued and outstanding, 20,459,700 and
17,002,341 shares                                         204,597        170,023
    Additional paid-in capital                         73,924,653     59,672,652
    Accumulated other comprehensive loss                  (61,564)     (116,659)
    Accumulated deficit                               (61,106,227)  (52,627,830)
                                                      -----------   ------------

                   Total stockholders' equity          12,961,459      7,098,186
                                                      -----------   ------------

TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY           $ 13,808,882    $ 7,559,772
                                                     ============   ============

See notes to consolidated financial statements.








CEL-SCI CORPORATION

CONSOLIDATED STATEMENTS OF OPERATIONS
YEARS ENDED SEPTEMBER 30, 2000, 1999, AND 1998
- --------------------------------------------------------------------------------

                                               2000         1999        1998

INVESTMENT INCOME                          $ 402,011     $ 402,831    $ 728,421

OTHER INCOME                                  40,540        66,687       64,573
                                            --------      --------      --------

           Total income                      442,551       469,518      792,994
                                            --------      --------      --------

OPERATING EXPENSES:
    Research and development               4,978,714     4,461,051    3,833,854
    Depreciation and amortization            220,994       268,210      295,331
    General and administrative             3,721,240     3,230,982    3,106,492
                                           ---------     ---------    ----------

             Total operating expenses      8,920,948     7,960,243    7,235,677
                                           ---------     ---------    ----------

NET LOSS                                   8,478,397     7,490,725    6,442,683

ACCRETION OF PREFERRED STOCK                       -             -    1,980,000
                                           ---------     ---------    ----------

NET LOSS ATTRIBUTABLE TO COMMON
    STOCKHOLDERS                          $8,478,397    $7,490,725   $8,422,683
                                          ==========    ==========   ===========

LOSS PER COMMON SHARE (BASIC)             $     0.44    $     0.52   $     0.74
                                          ==========    ==========   ===========

LOSS PER COMMON SHARE (DILUTED)           $     0.44    $     0.52   $     0.74
                                          ==========    ==========   ===========

WEIGHTED AVERAGE COMMON SHARES
    OUTSTANDING                           19,259,190    14,484,352   11,379,437
                                          ==========    ==========   ===========


See notes to consolidated financial statements.








CEL-SCI CORPORATION

CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
YEARS ENDED SEPTEMBER 30, 2000, 1999, AND 1998
- --------------------------------------------------------------------------------

                                                 2000       1999       1998

NET LOSS ATTRIBUTABLE TO COMMON
    STOCKHOLDERS                            $8,478,397   $7,490,725  $8,422,683

OTHER COMPREHENSIVE LOSS - Unrealized (gain)
    loss on investments                        (55,095)      68,368      44,792
                                            -----------  ----------  -----------

COMPREHENSIVE LOSS                           8,423,302    7,559,093   8,467,475
                                            ===========  ==========  ===========


See notes to consolidated financial statements.











CEL-SCI CORPORATION

CONSOLIDATED STATEMENTS OF STOCKHOLDERS'
EQUITY
YEARS ENDED SEPTEMBER 30, 2000, 1999, AND
1998
- --------------------------------------------------------------------------------

                                                                                                     

                                                                                      Accumulated
                                 Preferred                             Additional        Other
                               Series D Stock       Common Stock        Paid-In      Comprehensive       Accumulated
                             Shares      Amount  Shares      Amount      Capital     (Loss) Income         Deficit          Total


BALANCE, OCTOBER 1, 1997          -          -  10,445,691  $104,457   $44,419,244      $(3,499)       $(38,694,422)     $5,825,780


 Exercise of stock options        -          -     300,048     3,000       882,372            -                   -         885,372
 Exercise of warrants             -          -     768,243     7,682     3,621,744            -                   -       3,629,426
 Stock options issued to
  nonemployees for services       -          -           -         -       564,031            -                   -         564,031
 Issuance - Series D
  preferred stock, net of
  offering costs             10,000        100           -         -     9,499,900            -                   -       9,500,000
 Preferred Series D
   conversion                  (998)       (10)    441,333     4,413        (4,403)           -                   -               -
 401(k) contributions             -          -      17,380       174        57,976            -                   -          58,150
 Change in unrealized
   gain (loss) of
   marketable securities
   available for sale             -          -           -         -             -      (44,792)                  -         (44,792)
    Net loss                      -          -           -         -             -            -          (6,442,683)     (6,442,683)
                              ------------------------------------------------------------------------------------------------------
BALANCE, SEPTEMBER 30, 1998   9,002         90   11,972,695  119,726    59,040,864      (48,291)        (45,137,105)     13,975,284

 Exercise of stock options        -          -       28,500      285        70,965            -                   -          71,250
 Stock options issued to
   nonemployees
   for services                   -          -            -        -        88,166            -                   -          88,166
 Preferred Series D
   conversion                (9,002)       (90)   4,760,126   47,602       (47,512)           -                   -               -
 401(k) contributions             -          -       41,020      410        86,544            -                   -          86,954
 Stock bonus to officer           -          -      200,000    2,000       433,625            -                   -         435,625
 Change in unrealized gain
   (loss) of marketable
   securities available
   for sale                       -          -            -        -             -      (68,368)                  -         (68,368)
    Net loss                      -          -            -        -             -            -          (7,490,725)     (7,490,725)
                             -------------------------------------------------------------------------------------------------------

BALANCE, SEPTEMBER 30, 1999       -          -   17,002,341  170,023    59,672,652     (116,659)        (52,627,830)      7,098,186

    Exercise of stock options     -          -    1,047,612   10,476     3,646,991            -                   -       3,657,467
    Issuance - common stock       -          -    2,175,258   21,753     9,958,247            -                   -       9,980,000
    401(k) contributions          -          -       34,489      345        98,762            -                   -          99,107
    Stock bonus to officer        -          -      200,000    2,000       548,000            -                   -         550,000
 Change in unrealized gain
  (loss) of marketable
  securities available
  for sale                        -          -            -        -             -       55,095                   -          55,095
    Net loss                      -          -            -        -             -            -          (8,478,397)     (8,478,397)
                             -------------------------------------------------------------------------------------------------------

BALANCE, SEPTEMBER 30, 2000       -         $-   20,459,700 $204,597   $73,924,653     $(61,564)       $(61,106,227)    $12,961,459
                             =======================================================================================================




See notes to consolidated financial statements.







CEL-SCI CORPORATION

CONSOLIDATED STATEMENTS OF CASH FLOWS
YEARS ENDED SEPTEMBER 30, 2000, 1999, AND 1998
- --------------------------------------------------------------------------------

                                                  2000        1999       1998

CASH FLOWS FROM OPERATING ACTIVITIES:
    Net loss                                 $(8,478,396) (7,490,725)(6,442,683)
    Adjustments to reconcile net loss
     to net cash used in operating
     activities:
        Depreciation and amortization            220,994     268,210    295,331
        Issuance of stock options for services         -      88,166    564,031
        Stock bonus granted to officer           550,000     435,625          -
        Stock contributed to 401(k) plan          99,107      86,954     58,150
        Net realized loss on sale of
           securities                             49,962     151,349          9
        Changes in assets and liabilities:
          Increase in interest and other
            receivables                           23,573       6,984     36,625
          (Increase) decrease in prepaid
            expenses                          (1,323,804)    209,262   (313,046)
          Decrease (increase) in advances         68,720     (69,275)     4,733
          (Increase) decrease in deposits       (125,000)          -      3,350
          Decrease (increase) in accounts
             payable and accrued expenses        389,336       6,118    (54,440)
          (Increase) decrease in deferred
             rent                                 (3,499)     (1,061)     2,352
                                                  --------   --------     -----

             Net cash used in
                   operating activities       (8,529,007) (6,308,393)(5,845,588)

CASH FLOWS PROVIDED BY (USED IN)
    INVESTING ACTIVITIES:
    Purchases of investments                  (2,000,587) (235,698) (13,480,816)
    Sales and maturities of investments        1,436,289 6,499,801    4,501,828
    Repayment on note receivable from
shareholder                                            -    70,809      216,066
    Expenditures for property and equipment     (284,043)  (60,552)     (70,559)
    Expenditures for patents                     (98,500) (102,798)     (35,211)
                                                --------- ----------   --------

           Net cash (used in) provided by
               investing activities             (946,841) 6,171,562  (8,868,692)
                                                --------- ---------  -----------


                                                                 (Continued)






CEL-SCI CORPORATION

CONSOLIDATED STATEMENTS OF CASH FLOWS
YEARS ENDED SEPTEMBER 30, 2000, 1999, AND 1998
- --------------------------------------------------------------------------------

                                                  2000        1999       1998

CASH FLOWS PROVIDED BY
    FINANCING  ACTIVITIES:
    Cash proceeds from issuance of preferred
and common stock and warrant conversion
 for cash                                     13,637,467    71,250   14,018,899
                                              ------------  -------- ----------

                   Net  cash provided by
                     financing activities     13,637,467    71,250   14,018,899
                                              ------------  -------- ----------

NET INCREASE (DECREASE) IN CASH                4,161,619   (65,581)    (695,381)

CASH, BEGINNING OF YEAR                        2,747,644 2,813,225    3,508,606
                                               --------- ---------   -----------

CASH, END OF YEAR                             $6,909,263 $2,747,644  $2,813,225
                                              ========== ==========  ==========

SUPPLEMENTAL DISCLOSURES:

     At September 30, 2000,  1999, and 1998,  the net unrealized  gain (loss) on
investments   available-for-sale   was  $61,564,   $(116,659),   and   (48,291),
respectively.

    During the year ended September 30, 1999, 9,002 shares of Series D Preferred
Stock were converted into 4,760,126 shares of common stock.

                                                                   (Concluded)


See notes to consolidated financial statements.











CEL-SCI CORPORATION

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
YEARS ENDED SEPTEMBER 30, 2000, 1999 AND 1998
- --------------------------------------------------------------------------------

1.  ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

CEL-SCI  Corporation  (the Company) was  incorporated  on March 22, 1983, in the
State of Colorado, to finance research and development in biomedical science and
ultimately to engage in marketing products.

Significant accounting policies are as follows:

        Principles of  Consolidation  - The  consolidated  financial  statements
        include  the  accounts  of  CEL-SCI  Corporation  and its  wholly  owned
        subsidiaries,   Viral   Technologies,   Inc.,   and  MaxPharma  AG.  All
        significant   intercompany   transactions   have  been  eliminated  upon
        consolidation.

        Investments  -  Investments  that  may be sold as part of the  liquidity
        management  of the  Company  or for  other  factors  are  classified  as
        available-for-sale  and are  carried at fair  market  value.  Unrealized
        gains and losses on such securities are reported as a separate component
        of  stockholders'  equity.   Realized  gains  and  losses  on  sales  of
        securities  are  reported in earnings  and  computed  using the specific
        identified cost basis.

        Research  and Office  Equipment  -  Research  and  office  equipment  is
        recorded at cost and  depreciated  using the  straight-line  method over
        estimated useful lives of five to seven years.

        Research and Development  Costs - Research and development  expenditures
        are expensed as incurred. The Company has an agreement with an unrelated
        corporation for the production of MULTIKINE, which is the Company's only
        product source.

        Research  and   Development   Grant  Revenues  -  The  Company's   grant
        arrangements are handled on a reimbursement  basis. Costs incurred under
        the  arrangements  are expensed as incurred.  Subsequent  reimbursements
        from the granting agency are applied against such expenses.

        Patents - Patent  expenditures  are  capitalized and amortized using the
        straight-line  method over 17 years.  In the event changes in technology
        or  other  circumstances  impair  the  value  or  life  of  the  patent,
        appropriate  adjustment in the asset value and period of amortization is
        made.

        Net Loss Per Share - Net loss per common  share is  computed by dividing
        the net loss,  after increasing the loss for the effect of any preferred
        stock  dividends,  by the  weighted  average  number  of  common  shares
        outstanding  during the  period.  Common  stock  equivalents,  including
        options to purchase common stock, were excluded from the calculation for
        all periods presented as they were antidilutive.

        Prepaid   Expenses  -  The  majority  of  prepaid  expenses  consist  of
        manufacturing production advances, bulk purchases of laboratory supplies
        to be  consumed  in the  manufacturing  of  the  Company's  product  for
        clinical studies and the cost of options for nonemployee services.




        Income Taxes - Income taxes are accounted for using the liability method
        under which deferred tax  liabilities or assets are determined  based on
        the difference  between the financial  statement and tax bases of assets
        and liabilities  (i.e.,  temporary  differences) and are measured at the
        enacted tax rates.  Deferred tax expense is  determined by the change in
        the liability or asset for deferred taxes.

        Statement of Cash Flows - For purposes of the  statements of cash flows,
        cash  consists   principally  of  unrestricted  cash  on  deposit,   and
        short-term money market funds.  The Company  considers all highly liquid
        investments  with a  maturity  of  less  than  three  months  to be cash
        equivalents.

        Use of Estimates - The preparation of financial statements in conformity
        with accounting  principles  generally  accepted in the United States of
        America  requires  management  to make  estimates and  assumptions  that
        affect the reported  amounts of assets and liabilities and disclosure of
        contingent   assets  and  liabilities  at  the  date  of  the  financial
        statements and the reported  amounts of revenues and expenses during the
        reporting period. Actual results could differ from those estimates.

        Reclassifications - Certain reclassifications have been made to the 1999
        and  1998  financial   statements  to  conform  with  the   current-year
        presentation.

2.  INVESTMENTS

The   carrying    values   and   estimated    market   values   of   investments
available-for-sale at September 30, 2000 and 1999, are as follows:

                                            September 30, 2000

                                          Gross       Gross       Market Value
                             Amortized   Unrealized Unrealized  at September 30,
                               Cost       Gains      Losses           2000

      Bonds                $ 2,000,000   $4,720        $-        $ 2,004,720

      Fixed income mutual
      funds                  1,822,486        -    (66,284)       1,756,202
                            ----------       --   ---------       ---------

      Total                 $3,822,486   $4,720   $(66,284)      $3,760,922
                            ==========   ======   =========      ==========

                                         September 30, 1999
                                         Gross       Gross       Market Value
                       Amortized       Unrealized  Unrealized  at September 30,
                         Cost            Gains       Losses         1999

      Fixed income
      mutual funds    $3,308,150          $ -      $(116,659)     $3,191,491
                      ----------           --      ----------      ---------

      Total           $3,308,150          $ -      $(116,659)     $3,191,491
                      ============    ========    ===========      ==========

The gross realized  gains and losses of sales of investments  available-for-sale
for the years ended September 30, 2000, 1999, and 1998, are as follows:






                                                 2000       1999      1998
                                                 ----       ----      ----

    Realized gains                              $  -        $ -      $1,485

    Realized losses                           49,962    151,349       1,494
                                              ------   --------     -------

    Net realized loss                       $(49,962) $(151,349)     $  (9)
                                            ========= ==========        ===

3.    RESEARCH AND OFFICE EQUIPMENT

Research and office  equipment at  September  30, 2000 and 1999,  consist of the
following:

                                                    2000              1999

    Research equipment                          $ 2,052,082      $ 1,781,666

    Furniture and equipment                         258,780          245,154

    Leasehold improvements                            5,393            5,393
                                                -----------       ----------
                                                  2,316,255        2,032,213

    Less accumulated depreciation and
       amortization                              (1,721,336)      (1,563,586)
                                                ------------      -----------

    Net research and office equipment          $    594,919        $ 468,627
                                               ============       ==========

4.  INCOME TAXES

The approximate tax effect of each type of temporary difference and carryforward
that gave rise to the Company's deferred tax assets and liabilities at September
30, 2000 and 1999, is as follows:

                                                      2000          1999

    Depreciation                                  $ (28,964)     $(18,536)

    Prepaid expenses                               (697,848)     (101,769)

    Net operating loss carryforward              22,905,872    17,082,000

    Other                                             9,422        10,751

    Less:  Valuation allowance                  (22,188,482)  (16,972,446)
                                                --------------------------

    Net deferred                                          -             -
                                                ==========================

The  Company  has  available   for  income  tax  purposes  net  operating   loss
carryforwards of approximately $50,242,000, expiring from 2001 through 2020.

In the  event of a  significant  change in the  ownership  of the  Company,  the
utilization of such carryforwards could be substantially limited.




The difference in the Company's U.S.  Federal  statutory income tax rate and the
Company's effective rate is primarily attributed to the recording of a valuation
allowance due to the  uncertainty of the amount of future tax benefits that will
be realized  because it is more likely than not that future  taxable income will
not be sufficient to realize such tax benefits.

5.    STOCK OPTIONS, BONUS PLAN, AND WARRANTS

Non-Qualified  Stock  Option  Plan - At  September  30,  2000,  the  Company has
collectively  authorized the issuance of 3,260,000  shares of common stock under
the  Non-Qualified  Plan.  Options  typically vest over a three-year  period and
expire no later than ten years after the grant date. Terms of the options are to
be determined by the Company's Compensation Committee,  which administers all of
the plans.  The Company's  employees,  directors,  officers,  and consultants or
advisors are eligible to be granted options under the Non-Qualified Plan.

     Information  regarding  the  Company's  Non-Qualified  Stock Option Plan is
summarized as follows:

                                             Outstanding         Exercisable
                                          ------------------- ------------------
                                              Weighted              Weighted
                                              Average                Average
                                              Exercise              Exercise
                                     Shares    Price      Shares      Price

Options outstanding,
 October 1, 1997                   1,672,834  $3.44


   Options granted                   474,700   2.98

   Options exercised                (170,334)  2.92

   Options forfeited                 (17,500)  6.23
                                    ---------


Options outstanding,
  September 30, 1998               1,959,700   3.32      1,315,002    $3.10


   Options granted                   470,959   2.02

   Options forfeited                 (56,602)  4.78
                                  -----------


Options outstanding,
  September 30, 1999               2,374,057   2.80      1,595,934    3.09


   Options granted                   262,500   3.09

   Options exercised                (789,085)  3.41

   Options forfeited                 (46,266)  2.34
                                   ----------


Options outstanding,
  September 30, 2000               1,801,206   3.18      1,547,445   3.19
                                  ==========

     At September 30, 2000, options outstanding and exercisable were as follows:




                                                                                     


                                   Weighted Average     Weighted Average                     Weighted Average
Range of              Number        Exercise Price-        Remaining            Number        Exercise Price-
Exercise Prices      Outstanding    Outstanding         Contractual Life      Exercisable      Exerciseble


$1.87-$2.50           688,327          $2.11               3.0 years            633,263             $2.15
$2.56-$3.75           793,246           3.07               3.4 years            625,015              3.06
$3.87-$4.68           174,833           4.13               5.9 years            146,667              4.07
$5.00-$7.25           144,800           5.50               4.3 years            142,500              5.49





During 1999, the Company extended the expiration date on 35,000 options at $2.87
from the  Non-qualified  Stock Option Plan. The options were to expire March 30,
1999,  and were  extended to March 30,  2000.  The options had  originally  been
granted in December 1994. As of March 30, 2000, all options had been exercised.

During 1999, the Company  extended the  expiration  date on 750 options at $2.87
from the  Non-qualified  Stock Option Plan. The options were to expire March 31,
1999,  and were  extended to March 31,  2000.  The options had  originally  been
granted in March 1988. As of March 31, 2000, all options had been exercised.

During  March  2000,  the Company  agreed to restore and vest 40,000  options at
prices ranging from $5.25 to $5.62,  to one former  Director and one Director as
part of a settlement  agreement.  The options will expire on September 25, 2006.
As of September 30, 2000, 20,000 options had been exercised.

Incentive   Stock  Option  Plan  -  At  September  30,  2000,  the  Company  has
collectively  authorized the issuance of 1,600,000  shares of common stock under
the  Incentive  Stock  Option Plan.  Options  vest after one year to  three-year
period  and expire no later than ten years  after the grant  date.  Terms of the
options are to be  determined  by the Company's  Compensation  Committee,  which
administers  all of the plans.  Only the Company's  employees are eligible to be
granted options under the Incentive Plan.

Information regarding the Company's Incentive Stock Option Plan is summarized as
follows:

                                              Outstanding       Exercisable
                                            ----------------- ----------------
                                                     Weighted         Weighted
                                                     Average          Average
                                                     Exercise         Exercise
                                             Shares   Price   Shares   Price

Options outstanding, October 1, 1997        573,716   $3.81


   Options granted                          205,500    4.76

   Options exercised                         (3,166)   2.87

   Options forfeited                         (3,666)   5.34
                                          ----------


Options outstanding, September 30, 1998     772,384    4.06   311,622   $3.64


   Options granted                          206,500    2.14

   Options forfeited                         (2,034)   3.70
                                          ----------


Options outstanding, September 30, 1999     976,850    3.71   520,688    3.86


   Options granted                          140,000    3.77

   Options exercised                        (68,418)   4.47

   Options forfeited                         (1,666)   3.38
                                          ----------


Options outstanding, September 30, 2000   1,046,766   3.62    722,435   3.98
                                          ==========



At September 30, 2000, options outstanding and exercisable were as follows:

                                 Weighted    Weighted            Weighted
                                 Average      Average             Average
         Range of    Number    Exercise     Remaining   Number   Exercise
                                Price -                           Price -
         Exercise    OutstandinOutstanding  Contractual ExercisabExercisable
          Prices                               Life
        ------------ ---------------------  ----------- --------------------

          $1.94 -                $2.39      5.4 years              $2.51
           $2.87     322,500                            223,168
          $2.94 -                 3.45      7.4 years               3.47
           $4.31     406,900                            290,567
          $4.50 -                 5.07      7.3 years               5.11
           $6.00     316,766                            208,100
          $11.00         600     11.00      5.7 years       600    11.00



During 1999, the Company extended the expiration date on 23,000 options at $3.25
from the Incentive  Stock Option Plan.  The options were to expire  February 21,
1999, and were extended to February 21, 2000.  The options had  originally  been
granted in February 1996. All options were exercised as of September 30, 2000.

Stock  Bonus Plan - At  September  30,  2000,  the Company  has  authorized  the
issuance of 840,000  shares of common  stock  under the Stock  Bonus  Plan.  All
employees,  directors,  officers,  consultants,  and advisors are eligible to be
granted options.

Other  Options  and  Warrants - In  connection  with the 1992  public  offering,
5,175,000  common  stock  purchase  warrants  were  issued  and  outstanding  at
September 30, 1997. Every ten warrants entitled the holder to purchase one share
of common  stock at a price of $15.00 per share.  Subsequently,  the  expiration
date of the warrants was extended to February 1998.  Effective June 1, 1997, the
exercise  price of warrants was lowered  from $15 to $6 and only five  warrants,
rather than 10 warrants,  were  required to purchase one share of common  stock.
Subsequent to September 30, 1997, warrant-holders who tendered five warrants and
$6.00 between January 9, 1998, and February 7, 1998,  would receive one share of
the Company's  common stock and one new warrant.  The new warrants  would permit
the holder to purchase  one share of the  Company's  common  stock at a price of
$10.00 per share prior to February 7, 2000.  During 1998, the expiration date of
the  original  warrants  was  extended to July 31,  1998,  and 582,025  original
warrants were tendered for 116,405 common shares.  As of September 30, 1998, the
remaining 4,592,975 original warrants had expired.

During 1995, the Company granted a consultant  options to purchase 17,858 shares
 of the Company's common stock.  These shares became  exercisable on November 2,
 1995,  and were to expire  November  1, 1999.  In  February  2000,  the Company
 extended  the  expiration  date on the



options by one year to February 6, 2001.  These options are exercisable at $5.60
per share and as of September 30, 2000, all 17,858 options remain outstanding.

In June and September 1995, the Company  completed  private offerings whereby it
sold a total of 1,150,000  units at $2.00 per unit.  Each unit  consisted of one
share of Common  Stock and one  warrant.  Each  warrant  entitled  the holder to
purchase one  additional  share of Common Stock at a price of $3.25 per share at
any  time  prior to June 30,  1997.  All  warrants  sold in this  Offering  were
exercised  during  1996.  Additionally,  the Company  issued to the  underwriter
warrants to purchase  230,000 equity units.  Each unit consisted of one share of
the Company's common stock. For the June 1995 private  placement,  57,500 equity
units were issued at $2.00 per unit and another  57,500 equity units were issued
at $3.25 per unit.  All units  issued in the June 1995  private  placement  were
exercised  at September  30, 1996.  For the  September  1995 private  placement,
57,500  equity  units were  issued at $2.40 per unit and another  57,500  equity
units were issued at $3.25 per unit.  As of September  30, 1996,  21,890  equity
units had been  exercised  at $3.25 per unit and  21,890  equity  units had been
exercised at $2.40 per unit. As of September  30, 1997,  35,610 equity units had
been exercised at $2.40 per unit and 25,610 equity units were exercised at $3.25
per unit. All remaining 10,000 equity units will expire on February 6, 2001.

During 1997, the Company granted four consultants options to purchase a total of
268,000 shares of the Company's  common stock.  The fair value of the options is
expensed over the life of the  consultants'  contracts.  Of the 268,000 options,
218,000 options became  exercisable  during 1997 at prices ranging from $2.50 to
$4.50.  The remaining  50,000 options became  exercisable  during 1998 at $5.00.
During 1997,  50,000  options  were  exercised  at $3.50.  During 1998,  114,500
options  were  exercised  at prices  ranging  from $3.50 to $4.50.  During 1999,
18,500 options were exercised at prices ranging from $3.50 to $4.50. In December
1999, the Company extended the expiration date on 10,000 options  exercisable at
$3.25 per share to June 30, 2000. Subsequently, the expiration date was extended
to June 30, 2001.  During 2000,  25,000 options were exercised at prices ranging
from $2.50 to $3.94.  At September 30, 2000,  60,000 options related to the four
consultants remained outstanding at prices ranging from $3.50 to $5.00.

During 1998, the Company granted seven  consultants  options to purchase a total
of 282,000 shares of the Company's  common stock.  The fair value of the options
is expensed  over the life of the  consultants'  contracts.  All options  became
exercisable  during 1998 that were  exercisable  at prices ranging from $3.50 to
$7.31.  During 1998,  22,000 options were exercised at prices ranging from $3.50
to $4.50.  During 1999,  75,000 options  expired  ranging in price from $5.06 to
$7.31,  and 10,000 options were exercised at a price of $2.50. In December 1999,
the Company extended the expiration date on 20,000 options  exercisable at $3.94
per share and 10,000  options  exercisable  at $3.50 per share to June 30, 2000.
Subsequently,  the expiration  date was extended to June 30, 2001.  During 2000,
165,000  options  were  exercised  at prices  ranging  from  $2.50 to $5.62.  At
September  30,  2000,   5,000  options  related  to  the  consultants   remained
outstanding at a price of $3.50 per common share.

During 1999, the Company  granted one consultant  options to purchase a total of
50,000  shares of the Company's  common stock.  The fair value of the options is
expensed over the life of the consultant's  contract.  All 50,000 options became
exercisable  during 1999 at $2.50 per share.  At September 30, 2000,  all 50,000
options remained outstanding.



In January  1999,  the Company  revised the terms of 23,500 and 125,000  options
granted  to  consultants  in 1997  and  1998,  respectively.  The  terms  of the
agreements  set the exercise  price of the 148,500  options at $4.00 and set the
expiration date of the options at December 31, 1999. During 1999, 28,500 options
to purchase  shares were exercised at $2.50 per share.  The options were further
revised in December 1999 to extend the expiration date to June 30, 2001.  During
2000, all 120,000 options to purchase shares were exercised at $2.50 per share.

In connection with the December 1997 private offering, the Company issued to the
underwriters  warrants to purchase  50,000  shares of common  stock at $8.63 per
share.  The warrants are  exercisable at any time prior to December 22, 2000. At
September 30, 2000, all warrants remained outstanding.

In  connection  with the December  1999  private  offering,  the Company  issued
402,007  common stock  purchase  warrants.  Each warrant  entitled the holder to
purchase one share of common stock at $2.925 per share,  expiring December 2002.
The  investors  in this  private  offering  also  received  warrants  that allow
investors  under  certain  circumstances  to  acquire  additional  shares of the
Company's  common stock at a nominal price.  At September 30, 2000, all warrants
remained outstanding.

In connection with the March 2000 private  offering,  the Company issued 413,334
common stock purchase warrants. Each warrant entitled the holder to purchase one
share of common stock at $8.50 per share,  expiring March 2003. The investors in
this private offering also received  warrants that allow investors under certain
circumstances  to acquire  additional  shares of the Company's common stock at a
nominal price. At September 30, 2000, all warrants remained outstanding.

In October 1996, the Financial  Accounting  Standards Board issued  Statement of
Financial   Accounting   Standards   No.  123,   "Accounting   for   Stock-Based
Compensation"  (SFAS No. 123).  This  statement  encourages but does not require
companies  to account for  employee  stock  compensation  awards  based on their
estimated  fair  value at the grant  date with the  resulting  cost  charged  to
operations.  The Company  has  elected to  continue to account for its  employee
stock-based   compensation  using  the  intrinsic  value  method  prescribed  in
Accounting  Principles  Board  Opinion No. 25,  "Accounting  for Stock Issued to
Employees," and related Interpretations. If the Company had elected to recognize
compensation  expense based on the fair value of the awards granted,  consistent
with the  provisions  of SFAS No. 123, the  Company's  net loss and net loss per
common share would have been increased to the pro forma amounts indicated below:

                                             Year Ended September 30,
                                       --------------------------------------
                                          2000         1999         1998
                                          ----         ----         ----
                                                    (In Thousands)

Net loss:
    As reported
                                       $(8,478,396)$(7,490,725) $(6,442,638)
    Pro forma
                                       (8,908,999)  (8,124,159)  (7,018,634)

Loss per common share:
    As reported                         $    0.44     $   0.52     $   0.74

    Pro forma
                                             0.46         0.56         0.79




The weighted  average fair value at the date of grant for options granted during
2000, 1999, and 1998, was $2.57, $1.21, and $2.17 per option, respectively.

The fair value of each option  grant is estimated on the date of grant using the
Black-Scholes option-pricing model with the following assumptions:

                                                       2000    1999    1998
                                                       ----    ----    ----

     Expected stock risk volatility                     98 %    91 %   79 %
     Risk-free interest rate
                                                      6.32 %  5.48 %  5.49 %
     Expected life options                            4.91    3.23       2
     Expected dividend yield                             -       -       -

The  effects  of  applying  SFAS No.  123 in this pro forma  disclosure  are not
necessarily indicative of the effect on future amounts.

The Company's  stock options are not  transferable,  and the actual value of the
stock options that an employee may realize, if any, will depend on the excess of
the market price on the date of exercise  over the exercise  price.  The Company
has based its assumption  for stock price  volatility on the variance of monthly
closing  prices of the  Company's  stock from its initial  offering  date to the
present.  The  risk-free  rate  of  return  used  equals  the  yield  on one- to
three-year  zero-coupon U.S.  Treasury issues on the grant date. No discount was
applied to the value of the grants for nontransferability or risk of forfeiture.

6.  EMPLOYEE BENEFIT PLAN

The Company maintains a defined contribution  retirement plan,  qualifying under
Section 401(k) of the Internal Revenue Code, subject to the Employee  Retirement
Income Security Act of 1974, as amended, and covering  substantially all CEL-SCI
employees. Prior to January 1, 1998, the employer contributed an amount equal to
50% of  each  employee's  contribution  not to  exceed  3% of the  participant's
salary.  Effective January 1, 1998, the plan was amended such that the Company's
contribution  is now made in shares of the Company's  common stock as opposed to
cash. Each  participant's  contribution is matched by the Company with shares of
common stock that have a value equal to 100% of the participant's  contribution,
not  to  exceed  the  lesser  of  $10,000  or  6%  of  the  participant's  total
compensation.  The Company's contribution of common stock is valued each quarter
based upon the closing price of the Company's  common stock. The expense for the
years ended September 30, 2000, 1999, and 1998, in connection with this plan was
$99,107, $86,954, and $70,519, respectively.

7.  LEASE COMMITMENTS

Operating  Leases  -  The  future  minimum  annual  rental  payments  due  under
noncancelable operating leases for office and laboratory space are as follows:






                               Year Ending September 30,

                                         2001
                                                                    $202,934
                                         2002
                                                                     209,490
                                         2003
                                                                     180,035
                                         2004
                                                                      36,565
                                         2005                              -

                          Total minimum lease payments              $629,024
                                                                    ========

Rent  expense  for the years ended  September  30,  2000,  1999,  and 1998,  was
approximately $233,559, $214,205, and $165,067, respectively.

8.  STOCKHOLDERS' EQUITY

During  December  1997,  the Company  issued 10,000 shares of Series D Preferred
Stock for  $10,000,000.  The  issuance  included  550,000  Series A Warrants and
550,000 Series B Warrants.  The number of common shares issuable upon conversion
of the Preferred  Shares is  determinable  by dividing  $1,000 by $8.28 prior to
September 19, 1998, or at any time at which the Company's  common stock is $3.45
or less for five consecutive days. On or after September 19, 1998, the number of
common shares to be issued upon  conversion is determined by dividing  $1,000 by
the  lesser  of (1)  $8.28 or (2) the  average  price of the  stock  for any two
trading days during the ten trading days  preceding  the  conversion  date.  The
Series A Warrants  are  exercisable  at any time for $8.62 prior to December 22,
2001,  and the Series B Warrants are  exercisable at any time for $9.31 prior to
December  22, 2001.  Each  warrant  entitles the holder to purchase one share of
common stock.  At September 30, 1998, 998 shares of Series D Preferred Stock had
been converted into 441,333 shares of common stock. At September 30, 1999, 9,002
shares of Series D Preferred  Stock had been converted into 4,760,127  shares of
common stock.  There are no remaining  shares of Series D Preferred  Stock.  All
Series A and Series B Warrants issued remain  outstanding at September 30, 2000.
In connection with the Company's  December 1997  $10,000,000  Series D Preferred
Stock offering, the Series A and Series B warrants were assigned a relative fair
value of $1,980,000 in accordance  with APB No. 14,  Accounting for  Convertible
Debt and Debt Issued with Stock  Purchase  Warrants,  and have been  recorded as
additional  paid-in  capital.  The  $1,980,000  allocated  to the  warrants  was
accredited immediately.

9.  LOSS PER SHARE

Basic EPS  excludes  dilution  and is computed  by  dividing  net income or loss
attributable  to common  stockholders  by the weighted  average of common shares
outstanding  for the period.  Diluted EPS reflects the  potential  dilution that
could occur if securities or other contracts to issue common stock  (convertible
preferred  stock,  warrants to purchase  common stock and common  stock  options
using the treasury  stock method) were exercised or converted into common stock.
Potential  common shares in the diluted EPS computation are excluded in net loss
periods as their effect would be antidilutive.  The loss  attributable to common
stockholders  includes the impact of the  accretion of Series D Preferred  Stock
warrants and preferred stock dividends.






                                                     2000     1999     1998
                                                     ----     ----     ----

      Loss per common share (basic and diluted)     $0.44     $0.52   $0.74
                                                    ======    ======  =====

10. RECENT ACCOUNTING PRONOUNCEMENTS

In June 1998,  FASB issued SFAS No. 133,  Accounting for Derivative  Instruments
and  Hedging  Activities.  SFAS No. 133  establishes  accounting  and  reporting
standards for derivative  instruments  and for hedging  activities.  The Company
does not believe that the  adoption of SFAS No. 133 will have a material  effect
on its financial position or results of operation.

11. SEGMENT REPORTING

The  Company  adopted  Statement  of  Financial  Accounting  Standards  No. 131,
Disclosure  about  Segments of an Enterprise and Related  Information  (SFAS No.
131) in the fiscal  year ended  September  30,  1999.  SFAS No. 131  establishes
standards  for  reporting  information  regarding  operating  segments in annual
financial  statements and requires selected information for those segments to be
presented in interim financial reports issued to stockholders. SFAS No. 131 also
establishes  standards for related  disclosures  about products and services and
geographic  areas.  Operating  segments  are  identified  as  components  of  an
enterprise about which separate discrete financial  information is available for
evaluation by the chief  operating  decision maker, or decision making group, in
making decisions how to allocate resources and assess performance. The Company's
chief  decision  maker,  as defined  under SFAS No. 131, is the Chief  Executive
Officer.  To date,  the Company has viewed its  operations  as  principally  one
segment,  the research  and  development  of certain  drugs and  vaccines.  As a
result, the financial information disclosed herein, materially represents all of
the financial information related to the Company's principal operating segment.






                               CEL-SCI CORPORATION
                      CONSOLIDATED CONDENSED BALANCE SHEETS

                                     ASSETS
                                   (unaudited)

                                                December 31,      September 30,
CURRENT ASSETS:                                    2000              2000
                                                   ----              ----

  Cash and cash equivalents                  $  3,713,027      $  6,909,263
  Investments, net                              3,789,538         3,760,922
  Interest and other receivables                   29,646            39,252
  Prepaid expenses                              2,442,089         1,838,376
  Advances to officer/shareholder                  20,932               728
                                          ---------------     -------------

     Total Current Assets                       9,995,232        12,548,541

REASEARCH AND OFFICE EQUIPMENT-
  Less accumulated depreciation
  of $1,753,975 and $1,721,336                    601,093           594,919

DEPOSITS                                          139,828           139,828

PATENT COSTS-less accumulated
  amortization of $590,801 and $574,362           527,679            25,594
                                         ---------------- -----------------

                                          $    11,263,832   $    13,808,882
                                           ==============   ===============








            See notes to consolidated condensed financial statements






                               CEL-SCI CORPORATION
                      CONSOLIDATED CONDENSED BALANCE SHEETS

                       LIABILITES AND STOCKHOLDERS' EQUITY
                                   (unaudited)

                                                 December 31,     September 30,
                                                    2000              2000
                                                    ----              ----
CURRENT LIABILITIES:
  Accounts payable                             $  765,032        $  822,601

   Total current liabilities                      765,032           822,601

DEFERRED RENT                                      24,822            24,822
                                             ------------       -----------

      Total liabilities                         $ 789,854         $ 847,423

STOCKHOLDERS EQUITY
  Preferred stock, $.01 par value; authorized 1,000,000
      shares; no shares issued and outstanding
  Common stock, $.01 par value; authorized, 100,000,000
   shares; issued and outstanding, 20,479,265 and
      20,459,700 shares                           204,793           204,597
  Additional paid in capital                   73,951,849        73,924,653
  Net unrealized loss on equity securities        (32,948)          (61,564)
  Deficit                                     (63,649,716)      (61,106,227)
                                              ------------      ------------

TOTAL STOCKHOLDERS' EQUITY                     10,473,978        12,961,459
                                               ----------        ----------

                                            $  11,263,832     $  13,808,882
                                            =============     =============




            See notes to consolidated condensed financial statements






                               CEL-SCI CORPORATION
                               -------------------
                 CONSOLIDATED CONDENSED STATEMENTS OF OPERATIONS
                        ---------------------------------
                                   (unaudited)

                                                      Three Months Ended
                                                         December 31,
                                                   2000              1999
                                                   ----              -----
REVENUES:

  Interest income                                $183,211          $ 28,693
  Other income                                     66,597             1,355
                                              ------------       ----------

   TOTAL INCOME                                   249,808            30,048

 EXPENSES:
   Research and development                     2,017,007           995,024
   Depreciation and amortization                   49,079            70,780
   General and administrative                     727,211           668,652
                                              -----------        ----------

     TOTAL OPERATING EXPENSES                   2,793,297         1,734,456
                                                ---------        ----------

 NET LOSS                                      $2,543,489        $1,704,408
                                               ==========        ==========

LOSS PER COMMON SHARE (BASIC)              $         0.12    $         0.10
                                           ==============    ==============

 LOSS PER COMMON SHARE (DILUTED)           $         0.12    $         0.10
                                           ==============    ==============
WEIGHTED AVERAGE COMMON SHARES
           OUTSTANDING                         20,459,913        17,270,008
                                               ==========       ===========




                  See notes to condensed financial statements.






                               CEL-SCI CORPORATION
                               -------------------
                 CONSOLIDATED CONDENSED STATEMENTS OF CASH FLOW
                                   (unaudited)
                                                           Three Months Ended
                                                              December 31
                                                      --------------------------
                                                          2000       1999
CASH FLOWS FROM OPERATING ACTIVITIES
NET LOSS                                         $(2,543,489)    $(1,704,408)
Adjustments to reconcile net loss to
net cash used in operating activities:

  Depreciation and amortization                       49,079          70,780
  Stock issued to 401(k)                              27,391          22,498
  Net realized loss on sale of securities                 --          51,918

  Decrease (increase) in receivables                   9,606           7,676
  Decrease (increase) in prepaid expenses           (603,713)         51,151
  Decrease (increase) in advances                    (20,204)         56,154
  Increase (decrease) in accounts payable            (57,569)       (169,757)
                                                     --------       ---------
NET CASH USED IN OPERATING ACTIVITIES             (3,138,899)     (1,613,988)
                                                 ------------    ------------
CASH FLOWS PROVIDED BY (USED IN)
       INVESTING ACTIVITY:
Sales of investments                                      --       1,156,907
Purchase of investments                                   --              --
Purchase of research and office equipment            (38,813)        (31,430)
Patent costs                                         (18,524)        (42,888)
                                                  -----------   -------------
NET CASH USED IN INVESTING ACTIVITY                  (57,337)      1,082,589
                                                    ---------     ----------

CASH FLOWS PROVIDED BY (USED IN)
        FINANCING ACTIVITIES:
  Cash proceeds from issuance of preferred and common
      stock and warrant conversion for cash               --       2,355,000
                                                  ----------       ---------
NET CASH PROVIDED BY FINANCING ACTIVITIES                 --       2,355,000
                                                  ----------       ---------
NET INCREASE (DECREASE) IN CASH                   (3,196,236)      1,823,601

CASH AND CASH EQUIVALENTS:
  Beginning of period                              6,909,263       2,746,531
                                                -------------   ------------

End of period                                     $3,713,027      $4,570,132
                                                 ============    ===========


                  See notes to condensed financial statements.






                               CEL-SCI CORPORATION

             NOTES TO CONSOLIDATED CONDENSED FINANCIAL STATEMENTS

                 THREE MONTHS ENDED DECEMBER 31, 2000 AND 1999
                 ---------------------------------------------
                                  (unaudited)

A.    SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
      ------------------------------------------

      Basis of Presentation

      The accompanying financial statements have been prepared in accordance
      with rules established by the Securities and Exchange Commission for Form
      10-Q. Not all financial disclosures required to present the financial
      position and results of operations in accordance with generally accepted
      accounting principles are included herein. The reader is referred to the
      Company's financial statements included elsewhere in this prospectus for
      the year ended September 30, 2000. In the opinion of management, all
      accruals and adjustments (each of which is of a normal recurring nature)
      necessary for a fair presentation of the financial position as of December
      31, 2000 and the results of operations for the three-month period then
      ended have been made. Significant accounting policies have been
      consistently applied in the interim financial statements and the annual
      financial statements.

      Investments

      Investments that may be sold as part of the liquidity management of the
      Company or for other factors are classified as available-for-sale and are
      carried at fair market value. Unrealized gains and losses on such
      securities are reported as a separate component of stockholders' equity.
      Realized gains and losses on sales of securities are reported in earnings
      and computed using the specific identified cost basis.

      Loss per Share

      Net loss per common share is computed by dividing the net loss by the
      weighted average number of common shares outstanding during the period.
      Common stock equivalents, including options to purchase common stock, were
      excluded from the calculation because they are antidilutive due to the net
      losses.

      Long-lived Assets

              Statement of Accounting Standards No. 121, "Accounting for the
         Impairment of Long-lived Assets and for Long-lived Assets to be
         Disposed of" is effective for financial statements for fiscal years
         beginning after December 15, 1995.






                               CEL-SCI CORPORATION

             NOTES TO CONSOLIDATED CONDENSED FINANCIAL STATEMENTS

                 THREE MONTHS ENDED DECEMBER 31, 2000 AND 1999
                 ---------------------------------------------
                                  (unaudited)
                                  (continued)

B.          COMPREHENSIVE LOSS

               In fiscal  1999,  the  Company  adopted  Statement  of  Financial
               Accounting  Standard  ("SFAS") No. 130  "Reporting  Comprehensive
               Income"  which was  effective  for fiscal years  beginning  after
               December 15, 1997.  Comprehensive  income (loss) is the change in
               equity of a business enterprise during a period from transactions
               and other events and circumstances  from non-owner  sources.  The
               Company's  source of other  comprehensive  loss,  other  than net
               losses,  is from  unrealized  gain or  loss on  investments.  The
               components of comprehensive income (loss) are as follows:

                                        Three months ended    Three months ended
                                        December 31, 2000     December 31, 1999
                                        -----------------     -----------------

Net Loss                                     $2,543,489          $1,704,408
  Other Comprehensive Income:
  Unrealized Loss (Gain) From Investments       (28,617)            (18,713)
                                            ------------        ------------
      Comprehensive Loss                     $2,514,872          $1,685,695
                                            ============        ============






      No dealer salesman or other person has been authorized to give any
information or to make any representations, other than those contained in this
prospectus. Any information or representation not contained in this prospectus
must not be relied upon as having been authorized by CEL-SCI. This prospectus
does not constitute an offer to sell, or a solicitation of an offer to buy, the
securities offered hereby in any state or other jurisdiction to any person to
whom it is unlawful to make such offer or solicitation. Neither the delivery of
this prospectus nor any sale made hereunder shall, under any circumstances,
create an implication that there has been no change in the affairs of CEL-SCI
since the date of this prospectus.







                                TABLE OF CONTENTS

                                                                    Page
Prospectus Summary..................................
Risk Factors........................................
Comparative Share Data..............................
Market for CEL-SCI's Common Stock...................
Management's Discussion and Analysis of
  Financial Condition and Results of Operations.....
Business............................................
Management..........................................
Principal Shareholders..............................
Equity Line of Credit Agreement.....................
Selling Shareholder.................................
Description of Securities...........................
Experts.............................................
Indemnification.....................................
Additional Information..............................

                        ----------------------------- -
                                  Common stock

                               CEL-SCI CORPORATION

                                   PROSPECTUS














                                     PART II
                     Information Not Required in Prospectus


Item 13.  Other Expenses of Issuance and Distribution

             SEC Filing Fee
             Blue Sky Fees and Expenses
             Printing and Engraving Expenses
             Legal Fees and Expenses
             Accounting Fees and Expenses
             Miscellaneous Expenses

             TOTAL

             All expenses other than the S.E.C. filing fees are estimated.

Item 14.  Indemnification of Officers and Directors.
          -----------------------------------------

      It is provided by Section 7-109-102 of the Colorado Revised Statutes and
CEL-SCI's Bylaws that CEL-SCI may indemnify any and all of its officers,
directors, employees or agents or former officers, directors, employees or
agents, against expenses actually and necessarily incurred by them, in
connection with the defense of any legal proceeding or threatened legal
proceeding, except as to matters in which such persons shall be determined to
not have acted in good faith and in the best interest of CEL-SCI.

Item 15.  Recent Sales of Unregistered Securities.

      During the past three years CEL-SCI has sold unregistered securities to
the persons, in the amounts and for the consideration set forth below:

      Name                    Shares Sold       Consideration



Item 16.  Exhibits and Financial Statement Schedules

      (a)   Exhibits                                  Page Number

3(a)  Articles of Incorporation         Incorporated by reference to Exhibit
                                        3(a) of CEL-SCI's combined Registration
                                        Statement on Form S-1 and Post-Effective
                                        Amendment ("Registration Statement"),
                                        Registration Nos. 2-85547-D and 33-7531.






 (b)  Amended Articles                  Incorporated by reference to Exhibit
                                        3(a) of CEL-SCI's Registration Statement
                                        on Form S-1, Registration Nos. 2-85547-D
                                        and 33-7531.

 (c)  Amended Articles                  Incorporated  by reference to Exhibit
                                        (Name change only) 3(c) filed with
                                        Registration Statement on Form S-1
                                        (No. 33-34878).

 (d)  Bylaws                            Incorporated by reference to Exhibit
                                        3(b) of CEL-SCI's Registration Statement
                                        on Form S-1, Registration Nos. 2-85547-D
                                        and 33-7531.

4(a) Specimen copy of Stock Certificate  Incorporated by reference to Exhibit
                                        4(a) of CEL-SCI's Registration Statement
                                        on Form S-1, Registration Nos. 2-85547-D
                                        and 33-7531.

4(c)  Form of Common Stock              Incorporated by reference to Exhibit
                                       Purchase Warrant 4(c) filed as an exhibit
                                        to CEL-SCI's Registration  Statement on
                                        Form S-1 (Registration No. 33-43281).

5     Opinion of Counsel                  _______________________________

10(e) Employment Agreement with       Incorporated by reference to Exhibit 10(e)
      Geert Kersten                   of the Company's report on Form 10-K for
                                      the year ended September 30, 2000.

10(i) Securities Purchase Agreement   Incorporated by reference to Exhibit 10(i)
      (with schedule)                 to Cel-Sci Registration Statement on Form
                                      S-3 (Commission File Number 333-94675).

10(j)                                     Form of Callable (Series A) Warrant
                                          Incorporated by reference to Exhibit
                                          10(j) to Cel-Sci Registration
                                          Statement on Form S-3 (Commission File
                                          Number 333-94675).

10(k) Form of Adjustable (Series B)    Incorporated by reference to Exhibit
      Warrant                          10(k) to Cel-Sci Registration Statement
                                       on Form S-3 (Commission File Number
                                       333-94675).

10(l) Registration Rights Agreement    Incorporated by reference to Exhibit
                                       10(l) to Cel-Sci Registration Statement
                                       on Form S-3 (Commission File Number
                                       333-34604).






10(m) Securities Purchase Agreement,     Incorporated by reference to Exhibit
      together with Schedule required    10(m) to Cel-Sci Registration Statement
      Instruction 2 to Item 601 of       on by Form S-3 (Commission File Number
      Regulation S-K                     333-34604)

10(n) Form of Callable (Series C)        Incorporated by reference to Exhibit
      Warrant                            10(n) to Cel-Sci Registration
                                         Statement on Form S-3 (Commission File
                                         Number 333-34604).

10(o) Form of Adjustable (Series D)      Incorporated by reference to Exhibit
      Warrant                            10(o) to Cel-Sci Registration
                                         Statement on Form S-3 (Commission File
                                         Number 333-34604).

10(p) Registration Rights Agreement      Incorporated by reference to Exhibit
                                         10(p) to Cel-Sci Registration Statement
                                         on Form S-3 (Commission File Number
                                         333-34604).

10(q) Common Stock Purchase Agreement
      with Paul Revere Capital Partners
      Ltd.                                --------------------------------

10(r) Stock Purchase Warrant issued to
      Paul Revere Capital Partners, Ltd.  --------------------------------

23(a) Consent of attorneys                --------------------------------

23(b) Consent of accountants              ________________________________

      (b)   Financial statement schedules.                       None

Item 17. Undertakings.
         ------------

      The undersigned Registrant hereby undertakes:

      (1) To file, during any period in which offers or sales are being made, a
post-effective amendment to this Registration Statement.

            (i) To include any prospectus required by Section l0(a)(3) of the
 Securities Act of l933;

            (ii) To reflect in the prospectus any facts or events arising after
the effective date of the Registration Statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the Registration
Statement;

            (iii) To include any material information with respect to the plan
of distribution not previously disclosed in the Registration Statement or any
material change to such information in the Registration Statement, including
(but not limited to) any addition or deletion of a managing underwriter.




         (2) That, for the purpose of determining any liability under the
Securities Act of l933, each such post-effective amendment shall be deemed to be
a new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         Insofar as indemnification for liabilities arising under the Securities
Act of l933 may be permitted to directors, officers and controlling persons of
the Registrant, the Registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy
as expressed in the Act and is, therefore, unenforceable. In the event that a
claim for indemnification against such liabilities (other than the payment by
the Registrant of expenses incurred or paid by a director, officer or
controlling person of the Registrant in the successful defense of any action,
suit or proceeding) is asserted by such director, officer or controlling person
in connection with the securities being registered, the Registrant will, unless
in the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question of whether
such indemnification by it is against public policy as expressed in the Act and
will be governed by the final adjudication of such issue.











                                POWER OF ATTORNEY

         The registrant and each person whose signature appears below hereby
authorizes the agent for service named in this Registration Statement, with full
power to act alone, to file one or more amendments (including post-effective
amendments) to this Registration Statement, which amendments may make such
changes in this Registration Statement as such agent for service deems
appropriate, and the Registrant and each such person hereby appoints such agent
for service as attorney-in-fact, with full power to act alone, to execute in the
name and in behalf of the Registrant and any such person, individually and in
each capacity stated below, any such amendments to this Registration Statement.

                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of l933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
the requirements for filing on Form S-3 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Vienna, State of Virginia, on the 26th day of April,
2001.

                               CEL-SCI CORPORATION


                                       By:  /s/ Maximilian de Clara
                                            ---------------------------------
                                              Maximilian de Clara, President

      Pursuant to the requirements of the Securities Act of l933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.

Signature                            Title                    Date


 /s/ Maximilian de Clara          Director and Principal    April 26, 2001
Maximilian de Clara               Executive Officer

 /s/ Geert R. Kersten             Director, Principal       April 26, 2001
- ---------------------------       Financial Officer
Geert R. Kersten                  and Chief Executive
                                  Officer

 /s/ Alexander G. Esterhazy       Director                  April 26, 2001
- ------------------------------
Alexander G. Esterhazy

 /s/ F. Donald Hudson             Director                  April 26, 2001
- --------------------------------
F. Donald Hudson

 /s/ C. Richard Kinsolving        Director                  April 26, 2001
- -------------------------------
C. Richard Kinsolving