EXHIBIT 5







                                February 16, 2007

CEL-SCI Corporation
8229 Boone Blvd., Suite 802
Vienna, Virginia 22182

     This letter will constitute an opinion upon the legality of the sale by
CEL-SCI Corporation, a Colorado corporation, of up to 12,500,000 shares of
Common Stock, all as referred to in the Registration Statement on Form S-8 filed
by the Company with the Securities and Exchange Commission.

     We have examined the Articles of Incorporation, the Bylaws and the minutes
of the Board of Directors of the Company and the applicable laws of the State of
Colorado, and a copy of the Registration Statement. In our opinion, the Company
has duly authorized the issuance of the shares of stock mentioned above and such
shares when sold, will be legally issued, fully paid, and nonassessable.

                                Very truly yours,

                                  HART & TRINEN


                                  By /s/ William T. Hart
                                     William T. Hart