EXHIBIT 5







                               HART & TRINEN, LLP
                                ATTORNEYS AT LAW
                             1624 Washington Street
                                Denver, CO 80203
William T. Hart, P.C.              ________           Email:  harttrinen@aol.com
Donald T. Trinen                                      Facsimile:  (303) 839-5414
                                  (303) 839-0061
------

Will Hart
                                December 4, 2012

CEL-SCI Corporation
8229 Boone Boulevard, Suite 802
Vienna, Virginia  22182


      This letter will constitute our opinion upon the legality of the sale by
CEL-SCI Corporation, a Colorado corporation ("CEL-SCI"), of up to 35,000,000
shares of common stock, Series R warrants to purchase up to 26,250,000 shares of
CEL-SCI's common stock, as well as shares issuable upon the exercise of the
Series R warrants, all as referred to in the Registration Statement on Form S-3
(File No. 333-184094) filed with the Securities and Exchange Commission.

       We have examined the Articles of Incorporation, the Bylaws and the
minutes of the Board of Directors of CEL-SCI, the applicable laws of the State
of Colorado, and a copy of the Registration Statement. In our opinion:

     o    the  35,000,000  shares  of common  stock  mentioned  above  have been
          legally   issued   and  these   shares   represent   fully   paid  and
          non-assessable shares of CEL-SCI's common stock;

     o    the Series R warrants have been legally  issued and are fully paid and
          non-assessable; and

     o    the shares of common stock  issuable upon the exercise of the Series R
          warrants,  when the warrants are  exercised in  accordance  with their
          terms,  will be  legally  issued  and will  represent  fully  paid and
          non-assessable shares of CEL-SCI's common stock.

                                                    Very truly yours,

                                                    HART & TRINEN

                                                    /s/ William T. Hart

                                                    William T. Hart