UNITED CANNABIS CORPORATION 1600 Broadway, Suite 1600 Denver, CO 80202 (303) 386-7104 April 25, 2017 Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549 Re: United Cannabis Corporation Form S-1 File No. 333-216222 United Cannabis Corporation (the "Company") requests that the effective date of the above captioned Registration Statement be accelerated to Thursday, April 27, 2017 at 12:00 p.m. Eastern time, or as soon as practicable thereafter. The Company understands that: o should the Commission or the staff, acting pursuant to delegated authority, declare the filing effective, it does not foreclose the Commission from taking any action with respect to the filing; o the action of the Commission or the staff, acting pursuant to delegated authority, in declaring the filing effective, does not relieve the Company from its full responsibility for the adequacy and accuracy of the disclosure in the filing; and o the Company may not assert this action as defense in any proceedings initiated by the Commission or any person under the federal securities laws of the United States. Very Truly Yours, /s/ Earnest Blackmon Earnest Blackmon, President