EXHIBIT 4.10

                              INVESTMENT AGREEMENT

                  INVESTMENT AGREEMENT, dated as of July 17, 1998, between MEDIC
COMPUTER SYSTEMS, INC., a North Carolina corporation ("Medic"; and together with
its  affiliates,  the  "Investor"),  and MEDE  AMERICA  CORPORATION,  a Delaware
corporation  (the  "Issuer").  Capitalized  terms are  defined in the text or in
Section  6.7,  and  a  cross-reference   table  of  defined  terms  is  provided
immediately preceding the signature page hereto.

                                    RECITALS

                  WHEREAS,  the Issuer  desires that the Investor  enter into an
ongoing   commercial   relationship  with  the  Issuer  and  that  the  Investor
participate in the development of the Issuer's business on an ongoing basis.

                  WHEREAS,  the Issuer wishes to issue to the Investor,  and the
Investor wishes to accept, the Warrant.

                  NOW  THEREFORE,  in  consideration  of the  foregoing  and the
respective representations, warranties, covenants and agreements hereinafter set
forth, and for other good and valuable consideration the receipt and sufficiency
of which are hereby  acknowledged  by the parties  hereto,  the parties  hereto,
intending to be legally bound hereby, agree as follows:

                                    ARTICLE I

                          ISSUANCE OF WARRANTS; CLOSING

                  1.1.  Investment.  Upon the terms set forth in this Agreement,
and in reliance upon the  representations  and warranties  contained herein, the
Issuer is  issuing to the  Investor,  and the  Investor  is  accepting  from the
Issuer, the Warrant (the "Issuance").

                  1.2.  Closing.  Subject  to the terms and  conditions  of this
Agreement,  the  closing  of  the  Issuance  (the  "Closing")  is  taking  place
concurrently  with the execution and delivery hereof at the offices of Debevoise
& Plimpton,  875 Third Avenue, New York, New York. The date on which the Closing
is occurring is hereinafter referred to as the "Closing Date".





                  1.3. Deliveries at Closing.  At the Closing,  (a) the Investor
is delivering to the Issuer the Registration  Rights Agreement duly executed and
any certificates or other  instruments  required by this Agreement,  and (b) the
Issuer is delivering to the Investor (i) a duly executed Warrant,  registered in
the name of the Investor,  (ii) the Registration  Rights Agreement duly executed
and  (iii)  any  other  certificates  or  other  instruments  required  by  this
Agreement.  The  Stockholders  Agreement has been, or  concurrently  herewith is
being, executed and delivered by the parties thereto.

                                   ARTICLE II

                          REPRESENTATIONS OF THE ISSUER

                  The Issuer hereby  represents  and warrants to the Investor as
follows:

                  2.1. Corporate Organization. The Issuer is a duly incorporated
and validly existing corporation in good standing under the laws of the State of
Delaware.

                  2.2.  Authorization; Validity.

                  (a) The  Issuer  has the  corporate  power  and  authority  to
execute,  deliver and perform  its  obligations  under,  and to  consummate  the
transactions  contemplated by, this Agreement and the Other Agreements,  and has
taken all necessary  corporate  action to authorize the execution,  delivery and
performance by the Issuer of, and consummation by the Issuer of the transactions
contemplated by, this Agreement and the Other Agreements. This Agreement and the
Other  Agreements  have been duly and  validly  executed  and  delivered  by the
Issuer, and this Agreement and the Other Agreements constitute valid and binding
obligations  of the Issuer,  enforceable  against the Issuer in accordance  with
their respective terms,  subject,  as to enforcement of remedies,  to applicable
bankruptcy,  insolvency,  moratorium  and  other  similar  laws  and to  general
principles of equity,  and, in the case of the  Registration  Rights  Agreement,
except as rights to indemnity or  contribution  thereunder may be limited by law
or public policy.

                  (b)  The  issuance,  sale  and  delivery  of  the  Warrant  in
accordance  with this  Agreement and the  issuance,  sale and delivery of Shares
upon  exercise  of the  Warrant  have  been  duly  authorized  by all  requisite
corporate action on the part of the Issuer, and, when issued, sold and delivered
in accordance  with this Agreement or the Warrant,  as applicable,  will be duly
and validly issued and, in the case of the Shares, fully paid and nonassessable,
and such issuance, sale and delivery will not give rise to any preemptive rights
on the part of any person.

                                       2





                  2.3.  No  Violation.  Neither  the  execution,   delivery  nor
performance  by the  Issuer  of this  Agreement  and the Other  Agreements,  nor
compliance by the Issuer with the terms and provisions  hereof and thereof,  nor
the  consummation  by the  Issuer  of the  transactions  contemplated  herein or
therein,  will (a) contravene any applicable provision of any law, statute, rule
or regulation.  or any applicable order, writ, injunction or decree of any court
or  governmental  instrumentality,  (b) conflict  with or result in any material
breach of any term,  covenant,  condition or other provision of, or constitute a
material  default  under the terms of any  contractual  obligation  to which the
Issuer is a party or by which it or any of its properties or assets are bound or
to which it may be subject, or (c) violate or conflict with any provision of the
constituent documents of the Issuer.

                  2.4.  Registration  Statement.  The Registration  Statement on
Form S-1 of the Issuer (No. 333-55977) (the "Registration  Statement") does not,
in the form filed with the Securities and Exchange  Commission (the "SEC") as of
the date  hereof,  contain any untrue  statement  of a material  fact or omit to
state a material  fact  required to be stated  therein or  necessary to make the
statements  therein,  in light of the circumstances  under which they were made,
not misleading,  provided, that no representation is being made hereby as to the
disclosure in the Registration Statement regarding the transactions contemplated
by this  Agreement,  the Other  Agreements,  the  Stockholders  Agreement or the
Transaction Processing Agreement.

                                   ARTICLE III

                         REPRESENTATIONS OF THE INVESTOR

                  The Investor represents and warrants to the Issuer as follows:

                  3.1.  Organization.  The Investor is duly  organized,  validly
existing and in good standing under the laws of the State of North Carolina.

                  3.2. Authorization;  Validity. The Investor has full power and
authority  to  execute,  deliver  and  perform  its  obligations  under,  and to
consummate the transactions contemplated by, this Agreement and the Registration
Rights  Agreement.  The execution,  delivery and  performance by the Investor of
this Agreement and the Registration  Rights  Agreement,  and the consummation by
the Investor of the transactions  contemplated hereby and thereby have been duly
authorized by the Investor. This Agreement and the Registration Rights Agreement
have been duly and validly  executed  and  delivered by the  Investor,  and this
Agreement and the Registration Rights Agreement constitute valid and


                                       3



binding  obligations  of the  Investor,  enforceable  against  the  Investor  in
accordance with their respective terms,  subject, as to enforcement of remedies,
to applicable bankruptcy,  insolvency,  moratorium and other similar laws and to
general  principles  of  equity,  and,  in the case of the  Registration  Rights
Agreement,  except as rights to  indemnity  or  contribution  thereunder  may be
limited by law or public policy.

                  3.3.  No  Violation.  Neither  the  execution,   delivery  nor
performance  by the  Investor  of  this  Agreement  or the  Registration  Rights
Agreement,  nor compliance by the Investor with the terms and provisions  hereof
and  thereof,   nor  the  consummation  by  the  Investor  of  the  transactions
contemplated herein or therein,  will (a) contravene any applicable provision of
any law, statute, rule or regulation,  or any applicable order, writ, injunction
or decree of any court or  governmental  instrumentality,  (b) conflict  with or
result  in any  material  breach  of any  term,  covenant,  condition  or  other
provision  of,  or  constitute  a  material  default  under,  the  terms  of any
contractual obligation to which the Investor is a party or by which the Investor
or any of its  properties  or assets are bound or to which the  Investor  may be
subject,  or (c)  violate or  conflict  with any  provision  of the  constituent
documents of the Investor.

                  3.4.  Investment Representations, Etc.

                  (a) Purchase for Investment. The Warrant being acquired by the
         Investor  pursuant to this  Agreement and the Shares to be purchased by
         the Investor upon exercise of the Warrant is being and will be acquired
         for  investment  only  and not with a view to any  public  distribution
         thereof in violation of any of the  requirements  of the Securities Act
         of  1933,  as  amended  (the  "Securities   Act"),  or  the  rules  and
         regulations thereunder.

                  (b) Securities Not Registered.  The Investor  understands that
         the Warrant and the Shares to be purchased upon exercise of the Warrant
         have not been  registered  under the  Securities  Act in reliance  upon
         exemptions  contained in the Securities Act and applicable  regulations
         promulgated  thereunder  or  interpretations  thereof,  and  cannot  be
         offered for sale,  sold or  otherwise  transferred  unless such sale or
         transfer is so registered or qualifies for exemption from  registration
         under the Securities Act.

                  (c)  Sophistication.  The  Investor  has  such  knowledge  and
         experience  in  financial  and  business  matters that it is capable of
         evaluating  the merits and risks of its  investment  in the Warrant and
         the  Shares to be  purchased  upon  exercise  of the  Warrant,  and the
         Investor  understands and is able to bear any economic risks associated
         with such investment (including the necessity of holding such

                                       4





         securities  for  an  indefinite  period  of  time,   inasmuch  as  such
         securities  have not been,  and may not in the  foreseeable  future be,
         registered under the Securities Act), including the risk of the loss of
         the  Investor's  entire  investment in the Warrant and the Shares to be
         purchased upon exercise of the Warrant.

                  (d)  Legends.   The  Investor   understands  and  agrees  that
         certificates  representing  the Warrant and the Shares to be  purchased
         upon  exercise  of  the  Warrant  will  bear  conspicuous   legends  in
         substantially the form set forth below (in addition to any other legend
         required by law):

         THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED
         UNDER EITHER THE  SECURITIES  ACT OF 1933, AS AMENDED (THE "1933 ACT"),
         OR APPLICABLE STATE  SECURITIES LAWS (THE "STATE ACTS"),  AND SHALL NOT
         BE  SOLD,  PLEDGED,  HYPOTHECATED,  DONATED  OR  OTHERWISE  TRANSFERRED
         (WHETHER OR NOT FOR CONSIDERATION) BY THE HOLDER EXCEPT BY REGISTRATION
         OR PURSUANT TO AN EXEMPTION FROM  REGISTRATION UPON THE ISSUANCE TO THE
         COMPANY OF A FAVORABLE OPINION OF COUNSEL OR OTHER EVIDENCE  REASONABLY
         SATISFACTORY  TO THE COMPANY TO THE EFFECT THAT ANY SUCH TRANSFER SHALL
         NOT BE A VIOLATION OF THE 1933 ACT AND THE STATE ACTS.

Notwithstanding  the foregoing,  the certificate(s)  representing the Warrant or
the Shares to be  purchased  upon  exercise of the Warrant  need not continue to
bear such legend (and the Issuer  agrees to cause such legend to be removed from
such  certificate(s)  at the  request of the holder  thereof) if (i) the sale or
other  transfer of such  securities  referred to in such legend is in accordance
with the  provisions  of Rule 144 under the  Securities  Act (or any other  rule
permitting  public sale without  registration  under the Securities Act) or (ii)
the opinion of counsel  referred to above is to the effect that the Investor and
any  subsequent  transferee  (other than an  affiliate  of the Issuer)  would be
entitled to transfer such securities in a public sale without registration under
the Securities Act.

                                   ARTICLE IV

                              BOARD REPRESENTATION

                  4.1.  Board  Membership.  The Board of Directors of the Issuer
(the  "Board")  shall take such action as is  necessary to appoint to the Board,
effective  as of the earlier of the closing of the  initial  public  offering of
common stock of the Issuer and

                                       5





March  31,  1999  (such  earlier  date,  the  "Appointment  Date"),  one  person
designated by the Investor (the "Investor Designee").  From the Appointment Date
through the Termination  Date, (a) the Issuer shall, upon the written request of
the  Investor,  nominate and  recommend  to the holders of the  Issuer's  voting
securities for election to the Board, one Investor Designee and (b) the Investor
may require  that an Investor  Designee  who is a member of the Board be removed
and replaced by another Investor  Designee,  in which case, (i) if any action to
effect the  foregoing  is required  on the part of the  holders of the  Issuer's
voting  securities,  the Issuer  shall take the  actions set forth in clause (a)
above,  and (ii) in the  case of the  replacement  of an  Investor  Designee  in
connection with his death,  resignation or removal, the Issuer, by action of the
Board, shall cause a replacement  Investor Designee to be appointed to the Board
to  fill  the   vacancy   caused  by  such   death,   resignation   or  removal.
Notwithstanding  the  foregoing,  the Issuer  shall not be  required to take any
action that would result in more than one Investor Designee being elected to the
Board at the same time. For purposes of this Agreement,  the "Termination  Date"
shall  mean  the  earlier  to  occur  of (x) the  date  on  which  the  Investor
collectively  own less than  seventy-five  percent (75%) (based on the number of
Shares owned plus the number of Shares  subject to the Warrant) of the number of
Shares  subject to the Warrant on the  Closing  Date  (subject to  anti-dilution
adjustments) and (y) the termination of the Transaction Processing Agreement.

                  4.2.  Observer  and  Monitoring  Rights.  From and  after  the
Appointment  Date and until the  Termination  Date,  the  Issuer  will  permit a
representative  designated  by the Investor to attend as an observer any meeting
from which the Investor Designee will be absent. The Issuer may require that any
representative designated pursuant to this Section 4.2 execute a confidentiality
agreement in customary  form and  reasonably  acceptable to such  representative
with respect to  confidential  information  of the Issuer made available to such
representative  pursuant to this Section 4.2, which  agreement  shall include an
acknowledgment of such  representative that in such capacity such representative
may  obtain  material  non-public   information   concerning  the  Issuer,  and,
accordingly,  will be subject to any  applicable  restrictions  pursuant to Rule
10b-5 under the Securities  Exchange Act of 1934, as amended, in connection with
such representative's possession of such information.  The Investor acknowledges
that the  provisions  of this  Section 4.2 shall not be construed to provide the
Investor with the right to  participate  in meetings of the Board or to exercise
any control over the affairs of the Issuer.

                                       6





                                    ARTICLE V

                             TERMINATION; AMENDMENT

                  5.1. Termination. This Agreement may be terminated at any time
by mutual written consent of the Investor and the Issuer.

                  5.2.  Effect of  Termination.  If this Agreement is terminated
pursuant to Section 5.1 hereof,  this  Agreement,  except for the  provisions of
Sections 5.2, 6.1, 6.4 and 6.5,  shall  terminate,  without any liability on the
part of any party or its  directors,  officers or  stockholders.  Nothing herein
shall  relieve  any party to this  Agreement  of  liability  for  breach of this
Agreement or prejudice  the ability of the  non-breaching  party to seek damages
from any  other  party  for any  breach  of this  Agreement,  including  without
limitation,  attorneys'  fees and the  right to pursue  any  remedy at law or in
equity.

                  5.3.  Amendment.  This Agreement may not be amended except by 
an instrument in writing signed on behalf of both of the parties.

                                   ARTICLE VII

                                  MISCELLANEOUS

                  6.1. Notices.  Any notice required to be given hereunder shall
be  sufficient  if in  writing,  and  sent  by  facsimile  transmission  (with a
confirmatory copy sent by overnight courier),  by courier service (with proof of
service),  hand  delivery  or  certified  or  registered  mail  (return  receipt
requested and first-class postage prepaid), addressed as follows:

If to the Issuer:                             If to the Investor:
Mede America Corporation                      Medic Computer Systems, Inc.
90 Merrick Avenue                             8601 Six Forks Road
Suite 501                                     Suite 300
East Meadow, New York 11554                   Raleigh, North Carolina 27615

Telephone:        (516) 542-4500              Telephone:        (919) 847-8102
Facsimile:        (516) 542-4508              Facsimile:         (919) 847-7110
Attention:        David M. Goldwin, Esq.      Attention:        Alan Winchester
                  General Counsel

With a copy to:                               With a copy to:

                                       7




Reboul, MacMurray, Hewitt, Maynard & Kristol Misys plc
45 Rockefeller Plaza                         Burleigh House
New York, New York  10111                    Chapel Oak
Telephone:  (212) 841-5700                   Salford Priors, England
Facsimile:  (212) 841-5725                   Worcs WR11 5SH

Attention:  Mark J. Tannenbaum, Esq.

                                             Tel: 011 44 1386 871-373
                                             Fax: 011 44 1386 871-045
                                             Attention: Ross Graham

                                             and

                                             Debevoise & Plimpton
                                             875 Third Avenue
                                             New York, New York 10022
                                             Telephone: (212) 909-6000
                                             Facsimile: (212) 909-6836
                                             Attention: Paul H.Wilson, Jr., Esq.

or to such other address as any party shall specify by written  notice so given,
and such  notice  shall  be  deemed  to have  been  delivered  as of the date so
telecommunicated, personally delivered or mailed.

                  6.2.  Assignment;  Binding Effect;  Third Party Beneficiaries.
Neither this Agreement nor any of the rights, interests or obligations hereunder
shall be assigned by any party hereto (whether by operation of law or otherwise)
without the prior  written  consent of the other party  provided  that Medic may
assign its rights  hereunder  to an  affiliate,  but nothing  shall  relieve the
assignor from its obligations hereunder. Subject to the preceding sentence, this
Agreement  shall be binding  upon and shall  inure to the benefit of the parties
hereto and their  respective  successors and assigns.  Notwithstanding  anything
contained  in  this  Agreement  to the  contrary,  nothing  in  this  Agreement,
expressed or implied, is intended to confer on any person other than the parties
hereto or their respective  heirs,  successors,  executors,  administrators  and
assigns any rights,  remedies,  obligations or liabilities under or by reason of
this Agreement.

                  6.3. Entire Agreement. This Agreement, the Registration Rights
Agreement,  the Warrant, and the Transaction Processing Agreement constitute the
entire agreement among the parties with respect to the subject matter hereof and
supersede all prior agreements and understandings among the parties with respect
thereto.

                                       8



                  6.4. Fees and Expenses. Each party will bear its own legal and
other expenses with respect to this Agreement and the transactions  contemplated
hereby.

                  6.5.  Governing Law. This  Agreement  shall be governed by and
construed in accordance with the laws of the State of New York without regard to
its rules of  conflict  of laws.  Each of the  Issuer  and the  Investor  hereby
irrevocably and unconditionally consents to submit to the exclusive jurisdiction
of the  courts of the  State of New York and of the  United  States  of  America
located  in the State of New York (the "New  York  Courts")  for any  litigation
arising out of or relating to this Agreement and the  transactions  contemplated
hereby (and agrees not to commence any  litigation  relating  thereto  except in
such courts), waives any objection to the laying of venue of any such litigation
in the New York  Courts  and  agrees not to plead or claim in any New York Court
that such litigation brought therein has been brought in an inconvenient forum.

                  6.6.  Headings.  Headings of the Articles and Sections of this
Agreement are for the  convenience  of the parties  only,  and shall be given no
substantive or interpretive effect whatsoever.

                  6.7. Interpretation;  Certain Definitions.  In this Agreement,
unless the context  otherwise  requires,  words  describing the singular  number
shall  include the plural and vice versa,  and words  denoting  any gender shall
include  all  genders  and  words   denoting   natural   persons  shall  include
corporations  and  partnerships  and vice versa.  Whenever the words  "include,"
"includes" or "including" are used in this Agreement, they shall be deemed to be
followed by the words "without limitation." As used in this Agreement, the words
"Subsidiary"  and "affiliate"  shall have the meanings  ascribed thereto in Rule
12b-2 under the Securities Exchange Act of 1934, as amended. The following terms
shall have the following meanings ascribed to them:

                  "Other  Agreements"  means the  Warrant  and the  Registration
         Rights Agreements.

                  "Registration  Rights Agreement" means the Registration Rights
         Agreement,  dated as of the date  hereof,  between  the  Issuer and the
         Investor, in the form attached hereto as Exhibit A.

                  "Share" means a share of common stock of the Issuer, $0.01 par
         value per share.

                  "Stockholders  Agreement"  means  the  Stockholders  Agreement
         between the Investor,  Welsh,  Carson,  Anderson & Stowe V, L.P., Welsh
         Carson,  


                                       9


         Anderson & Stowe VI,  L.P.,  WCAS Capital  Partners  II, L.P.,  William
         Blair Capital Parners V, L.P. and William Blair Leveraged  Capital Fund
         Limited Partnership,  dated as of the date hereof, in the form attached
         hereto as Exhibit B.

                  "Transaction   Processing  Agreement"  means  the  Transaction
         Processing  Agreement between the Issuer and the Investor,  dated as of
         the date hereof.

                  "Warrant"  means the warrant  issued by the Issuer to purchase
         1,250,000 Shares, identical to the form attached hereto as Exhibit C.

                  6.8.  Severability.  Any term or provision  of this  Agreement
which  is  invalid  or  unenforceable  in any  jurisdiction  shall,  as to  that
jurisdiction,   be   ineffective   to  the   extent   of  such   invalidity   or
unenforceability  without rendering invalid or unenforceable the remaining terms
and provisions of this Agreement or affecting the validity or  enforceability of
any of the terms or provisions of this Agreement in any other  jurisdiction.  If
any  provision  of  this  Agreement  is so  broad  as to be  unenforceable,  the
provision shall be interpreted to be only so broad as is enforceable.

                  6.9.  Enforcement of Agreement.

                  (a) The parties  hereto  agree that  irreparable  damage would
         occur in the event that any of the  provisions of this  Agreement  were
         not  performed in accordance  with its specific  terms or was otherwise
         breached.  It is accordingly  agreed that the parties shall be entitled
         to an injunction or injunctions  to prevent  breaches of this Agreement
         and to enforce  specifically the terms and provisions hereof in any New
         York Court,  this being in  addition to any other  remedy to which they
         are entitled at law or in equity.

                  (b) The  prevailing  party  in any  judicial  action  shall be
         entitled  to  receive  from  the  other  party  reimbursement  for  the
         prevailing  party's reasonable  attorneys' fees and disbursements,  and
         court costs.

                  6.10. Issuer  Acknowledgment.  The Issuer hereby  acknowledges
that  nothing  in  this  Agreement,  the  Other  Agreements,   the  Stockholders
Agreement,   the  Transaction   Processing  Agreement  or  any  other  agreement
contemplated  hereby  or  thereby  shall in any way  restrict  the  right of the
Investor from purchasing any securities of the Issuer from third parties, in the
market, or otherwise.

                  6.11.  Counterparts.  This  Agreement  may be  executed by the
parties  hereto in separate  counterparts,  each of which when so  executed  and
delivered  shall  be an  


                                       10


original,  but all such counterparts shall together  constitute one and the same
instrument.  Each  counterpart  may  consist of a number of copies  hereof  each
signed by less than all, but together signed by all, of the parties hereto.


                                       11



                                   DEFINITIONS



         Defined Term                                        Section Reference
         ------------                                        -----------------

                                                   
"Affiliate"                                                Section 6.7
 ---------
"Appointment Date"                                         Section 4.1
 ----------------
"Board"                                                    Section 4.1
 -----
"Closing"                                                  Section 1.2
 -------
"Closing Date"                                             Section 1.2
 ------------
"Investor"                                                 First Paragraph
 --------
"Investor Designee"                                        Section 4.1
 -----------------
"Issuance"                                                 Section 1.1
 --------
"Issuer"                                                   First Paragraph
 ------
"Medic"                                                    First Paragraph
 -----
"New York Courts"                                          Section 6.5
 ---------------
"Registration Rights Agreement"                            Section 6.7
 -----------------------------
"Registration Statement"                                   Section 2.4
 ----------------------
"Securities Act"                                           Section 3.4
 --------------
"SEC"                                                      Section 2.4
 ---
"Share"                                                    Section 6.7
 -----
"Software Development Agreement"                           Section 6.7
 ------------------------------
"Stockholder Agreement"                                    Section 6.7
 ---------------------
"Termination Date"                                         Section 4.1
 ----------------
"Transaction Processing Agreement"                         Section 6.7
 --------------------------------
"Warrant"                                                  Section 6.7
 -------


                                       12



                  IN WITNESS  WHEREOF,  this Investment  Agreement has been duly
executed and delivered as of the day and year first written above.

                                              MEDIC COMPUTER SYSTEMS, INC.

                                              By:
                                                 ------------------------------
                                                    Name:
                                                    Title:

                                              MEDE AMERICA CORPORATION

                                              By:
                                                 ------------------------------
                                                    Name:
                                                    Title:

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