Exhibit 99.1

Protalex Announces Stock Repurchase PR Newswire,  Monday,  September 22, 2003 at
09:22  ALBUQUERQUE,  N.M.,  Sep 22,  2003  /PRNewswire-FirstCall  via COMTEX/ --
Protalex Inc. (OTC  Bulletin  Board:  PRTX)  announced  today the  repurchase of
approximately  3 million  shares of its common stock.  The stock will be retired
into the Company  treasury.  The Company reports that the remaining  outstanding
shares now total approximately 16.7 million.

Statements   in  this   press   release   that  are  not   strictly   historical
are"forward-looking"statements   within  the  meaning  of  Section  27A  of  the
Securities Act of 1933 and Section 21E of the  Securities  Exchange Act of 1934.
These statements involve a high degree of risk and uncertainty,  are predictions
only and actual events or results may differ  materially from those projected in
such  forward-looking  statements.  Factors  that could cause or  contribute  to
differences  include  the  Company's  limited  operating  history,   uncertainty
regarding  viability and market  acceptance of the Company's  products,  and the
Company's dependence on reimbursement by third parties. These factors and others
are more fully described in the section  entitled"Risks Related to the Company's
Business"in  the  Company's  Registration  Statement  on Form  10-SB  (File  No.
00028385) as filed with the Securities and Exchange Commission.

SOURCE Protalex Inc.

CONTACT: Steven H. Kane, President/CEO of Protalex Inc.,

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