COMMERCIAL LEASE


THIS LEASE is made on the 1st day of December , 2003.
                          ---        --------

The Landlord hereby agrees to lease to the Tenant, and the Tenant hereby agrees
to hire and take from the Landlord, the Leased Premises described below pursuant
to the terms and conditions specified herein:

LANDLORD:   Union Square, L.P.              TENANT(S): PROTALEX, Inc.
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Address: P.O. Box 59                        Address:  717 Encino N. E., Suite 17
                  New Hope, PA 18938                  Albuquerque, NM  87102
Telephone:        (215) 862-1014            Telephone: 215-598-1179
Facsimile:        (215) 862-1023            Facsimile: 215-598-9590

1. Leased Premises. The Leased Premises are those premises described as:
Building: "A" Building

Address:          _145_ Union Square Drive
                  New Hope, PA  18938

Gross Floor Area of Leased Premises:    3,795 square feet, pursuant to attached
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plan.

2.       Term.
         A.       The term of the Lease ("Initial Term") shall be for a period
                  of Three ( 3 ) years, unless sooner terminated or extended, as
                  hereinafter provided, and shall commence on the 9th day of
                  January , 200_4 ("Commencement Date") and end on the 28th day
                  of February , 200_7 ("Expiration Date").

         B.       Commencement Date of the Initial Term is determined by
                  allowing sixty working days for build-out of the Leased
                  Premises, from the date Landlord receives a building permit
                  for the Leased Premises. (See Paragraph 9 below, Delivery of
                  Possession.)

         C.       If Tenant remains in possession of the Leased Premises with
                  the written consent of the Landlord after the lease Expiration
                  Date stated above (without exercising, if applicable, an
                  option to extend) this Lease will be converted to a
                  month-to-month Lease and each party shall have the right to
                  terminate the Lease by giving at least one month's prior
                  written notice to the other party.

         D.       The period commencing on the day the tenancy begins, and
                  ending on the last day of the twelfth month next succeeding
                  the commencement of the Initial Term of this Lease, shall
                  constitute the first lease year as used herein, and each
                  successive period of twelve months shall constitute a lease
                  year.

3. Option to Extend. Tenant is granted the right and option to extend the term
of this Lease for an additional one or two years beyond the Initial Term hereof
(each, an "extension period", together with the Initial Term, the "Term"), the
first extension period to commence upon the expiration of the initial term of
this Lease, provided that: A. Such option must be exercised, if at all, by
written notice from Tenant to Landlord given at least six (6) months prior
                  to the expiration of the then current Term;

B.                At the time of exercising each option, and at the commencement
                  of each extension period, this Lease shall be in full force
                  and effect and there shall exist no Event of Default by
                  Tenant; and

C.                In the event the foregoing option is effectively exercised,
                  all the terms and conditions contained in this Lease shall
                  continue to apply during any extension period.
4.                Base Rent.
         A.       The Tenant agrees to pay the ANNUAL BASE RENT of Ninety-One
                  Thousand, Eighty Dollars ($91,080.00 ) payable in equal
                  installments of $7,590.00 in advance on the first day of each
                  and every calendar month during the Initial Term of this Lease
                  without deduction or demand. (Note: See Paragraph 6,
                  Additional Rent, below)

         B.       Rent shall be payable to Landlord's address above.

         C.       Rent shall increase 5% per year during the Initial Term. Rent
                  for years one and two of the optional extension period of this
                  Lease shall increase at 2.5% per year.

         D.       Tenant shall pay a "late charge" of ten percent (10%) each
                  month on a cumulative basis of any installment of Rent (or any
                  such charge as may be considered Additional Rent under this
                  Lease) when paid more than ten (10) days after the due date.

         E.       Tenant shall pay $50.00 for any checks returned by the bank
                  for insufficient funds.

5.       Base Rent Adjustment. If in any tax year commencing with the fiscal
         year 2005 , the real estate taxes and property insurance on the land
         and Building, of which the Leased Premises are a part, are in excess of
         the amount of real estate taxes and property insurance thereon for the
         fiscal year 2003 (hereinafter called the "Base Year"), Tenant will pay
         to Landlord as Additional Rent hereunder, when and as designated by
         notice in writing by Landlord, 100% percent of Tenant's proportionate
         share of such increase in the real estate taxes and property insurance
         over the Base Year that may occur in each year of the term of this
         Lease or any extension or renewal thereof and proportionately for any
         part of a fiscal year.

6.       Additional Rent.
         A.       All sums of money required to be paid by Tenant under this
                  Lease (except for Base Rent), whether or not the same are
                  designated "Additional Rent", shall be owed by Tenant to
                  Landlord as rent. Base Rent and Additional Rent shall be
                  referred to sometimes as Rent.

         B.       Electric utilities for year one shall be charged for at a rate
                  of $2.00 per square foot ($632.50 per month).
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                  Utilities for subsequent years of the Term, or any extension
                  period thereof, shall be based on Tenant's pro-rata
                  share of the average monthly electric bill from year one of
                  the Lease Term.  In the event Tenant, and the tenant
                  for the adjacent space at 140 Union Square Drive, agree upon
                  terms to divide proportionate shares of the actual
                  monthly metered electric utility bill for the entire 6,164
                  square foot space, this Additional Rent shall
                  terminate and the electric utility bill shall be agreed upon
                  and paid for by the two tenant parties.  If this
                  agreement for pro rata payment between the two tenant parties
                  terminates, then Tenant shall resume payment as
                  designated above, beginning with year two.

7.       Common Area Maintenance Rent. Tenant shall be required to pay to
         Landlord Additional Rent for maintenance of common areas, which shall
         include cleaning of common hallways, washing the interior and exterior
         of windows, common area utilities, trash removal, snow removal,
         landscape maintenance and any other maintenance expenses that are of a
         general nature. The annual amount of Common Area Maintenance Rent for
         the first year of this Lease term is $2.00 per square foot of gross
         floor area. The monthly amount of Common Area Maintenance Rent for the
         Leased Premises for year one is $632.50.

8.       Security Deposit.  Upon execution of this Lease, the sum of
         Seven Thousand, Five Hundred Ninety  Dollars ($7,590.00 )
         ---------------------------------------------------------
         shall be deposited by the Tenant with the Landlord as security for the
         faithful performance of all the covenants and
         conditions of the lease by the said Tenant ("Security Deposit").
         The Security Deposit is not an advance rent deposit or
         measure of Landlord's damages in case of Tenant's default.  Upon each
         occurrence of an Event of Default hereunder,
         Landlord may use all or part of the Security Deposit to pay delinquent
         payments due under the Lease and the cost of any
         damages injury, expense of liability caused by such Event of Default
         without prejudice to any other right or remedy
         provided under this Lease, and law or in equity.  Tenant shall pay
         Landlord on demand the amount that will restore the
         Security Deposit to its original amount.  If the Tenant faithfully
         performs all the covenants and conditions on his part
         to be performed, then the Security Deposit (or portion thereof
         remaining) shall be returned to the Tenant, without
         interest.  This Security Deposit is not required to be placed in an
         escrow account.

9.                                  Delivery of Possession. If for any reason
                                    the Landlord cannot deliver possession of
                                    the Leased Premises to the Tenant on the
                                    Commencement Date, this Lease shall not be
                                    void or voidable, nor shall the Landlord be
                                    liable to the Tenant for any loss or damage
                                    resulting therefrom. However, there shall be
                                    an abatement of Rent for the period between
                                    the date upon which the Landlord delivers
                                    possession, which shall become the adjusted
                                    Commencement Date of the Term of this Lease
                                    and the date of payment for the initial
                                    installment of Base Rent.

10.                                 Use of Premises. The Leased premises may be
                                    used only for the following purpose(s):
                                    Office space and bio-tech
                                    laboratory
11.      Condition of Leased Premises; Maintenance and Repair: At the time of
         delivery of possession, the Leased Premises shall be in good order and
         repair and in the condition described in the Specifications for Union
         Square attached hereto as Exhibit B. The Tenant agrees to take good
         care of and maintain the Leased Premises in good condition through the
         term of the lease.

         Subject to the provisions of this Lease, Tenant shall make and pay the
         costs of all repairs and maintenance of all interior painting; repairs
         and maintenance of approved signs; and repairs and replacements of all
         floor coverings, lighting, and other fixtures and equipment inside the
         Leased Premises, and repair and restoration of all damaged plate glass
         in the Leased Premises unless such repairs are required due to the
         neglect of Landlord. Landlord will maintain the HVAC system at its sole
         cost, unless any repairs are a result of the Tenant's negligence, in
         which case, Tenant shall pay as Additional Rent, the cost of any such
         repairs. In the event Tenant's fit-out to the previously existing space
         layout require HVAC adjustment, any such adjustments shall be at
         Tenant's expense.

12. Utilities. Responsibility for all utilities and services that are furnished
to the Leased
         Premises shall be as designated below. The application for and
         connecting of utilities, as well as all services, shall be made by and
         only in the name of the responsible party.

         Electric   Tenant (see 6 B. above)   Water/Sewer   Tenant
                   -------------------------              ---------

         Trash  Landlord  Cleaning (interior) Tenant      Telephone Tenant
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13.      Compliance with Laws and Regulations. Tenant, at its expense, shall
         promptly comply with all federal, state, and municipal laws, orders,
         and regulations, and with all lawful directives of public officers,
         which impose any duty upon it or Landlord with respect to the Leased
         Premises. Tenant at its expense, shall obtain all required licenses or
         permits for the conduct of its business within the terms of this Lease,
         or for the making of repairs, alterations, improvements, or additions
         to the Leased Premises after delivery of possession. Landlord, when
         necessary, will join with the Tenant in applying for all such permits
         or licenses.

14.      Alterations and Improvements.  Tenant shall not make any alterations,
         improvements or additions to the Leased Premises
         without the prior written consent of Landlord, which consent shall
         not be reasonably withheld.  Tenant shall supply
         Landlord with a list of contractors and subcontractors, and
         with plans and specifications for all such alterations,
         improvements and additions prior to requesting such consent.
         All alterations, improvements and additions made by Tenant
         shall remain upon the Leased Premises at the expiration or earlier
         termination of this Lease and shall become the
         property of Landlord unless Landlord shall, prior to or after
         the termination of this Lease, have given written notice to
         Tenant to remove same or any of same, in which event Tenant shall
         remove such alterations, improvements and additions and
         restore the Premises to the same good order and condition in which
         it was on the Commencement Date.  Should Tenant fail
         so to do, Landlord may do so, and Tenant shall reimburse Landlord
         for Landlord's expenses, on demand.  All of such
         alterations, improvements or additions shall be made solely
         at Tenant's expense;  and Tenant agrees to indemnify, defend
         and save harmless Landlord (a) on account of any injury to third
         persons or property by reason of any such improvements,
         additions or alterations, and (b) from the payment of any claim
         on account of bills for labor or materials furnished or
         claimed to have been furnished in connection therewith.  Tenant
         agrees to procure all necessary licenses, permits and
         approvals before undertaking such work and to do all such work in
         a good and workmanlike manner, employing materials of
         first class quality and complying with all applicable governmental
         requirements.

15.      Assignment/Subletting Restrictions. Tenant may not assign this
         agreement or sublet the Leased Premises without the prior written
         consent of the Landlord, which consent shall not be unreasonably
         withheld. Any assignment, sublease or other purported license to use
         the Leased Premises by Tenant without the Landlord's consent shall be
         void and shall (at Landlord's option) terminate this Lease. In the
         event that Landlord shall provide its consent to an assignment or
         sublease of the Leased Premises, such consent (i) shall not constitute
         a waiver of Landlord's right to withhold its consent to a subsequent
         assignment or sublease; and (ii) shall not reduce Tenant's obligations
         under the Lease.

16.      Insurance.
         A.       By Landlord. Landlord shall at all times during the term of
                  this Lease, at its expense, insure and keep in effect on the
                  Building in which the Leased Premises are located, fire
                  insurance with extended coverage. The Tenant shall not permit
                  any use of the Leased Premises which will make voidable any
                  insurance on the property of which the Leased Premises are a
                  part, or on the contents of said property or which shall be
                  contrary to any law or regulation from time to time
                  established by the applicable fire insurance rating
                  association. Tenant shall on demand reimburse the Landlord,
                  and all other tenants, the full amount of any increase in
                  insurance premiums caused by the Tenant's use of the premises.

         B.       By Tenant. Tenant shall, at its expense, during the term
                  hereof, maintain and deliver to Landlord, upon request, public
                  liability and property damage and plate glass insurance
                  policies with respect to the Leased Premises. Such policies
                  shall name the Landlord and Tenant as insured, and have limits
                  of at least $1,000,000.00 for injury or death to any one
                  person and $1,000,000.00 for any one accident, and with
                  respect to damage to property and with full coverage for plate
                  glass. Such policies shall be in whatever form and with such
                  insurance companies as are reasonably satisfactory to
                  Landlord, and shall name the Landlord as additional insured,
                  and shall provide for at least ten days prior notice to
                  Landlord of cancellation.

17.      Indemnification of Landlord. Tenant shall defend, indemnify, and hold
         Landlord harmless from and against any claim, loss, expense or damage
         to any person or property in or upon the Leased Premises, arising out
         of Tenant's use or occupancy of the Leased Premises, or arising out of
         any act or neglect of Tenant or its servants, employees, agents, or
         invitees.

18.               Condemnation. If all or any part of the Leased Premises is
                  taken by eminent domain, this Lease shall expire on the date
                  of such taking, and the rent shall be apportioned as of that
                  date. No part of any such award shall belong to Tenant.

19.               Destruction of Premises. If the building in which the Leased
                  Premises is located is damaged by fire or other casualty,
                  without Tenant's fault, and the damage, in Landlord's sole
                  judgment, is so extensive as to effectively constitute a total
                  destruction of the property or building, this Lease shall
                  terminate and the Rent shall be apportioned to the time of the
                  damage. In all other cases of damage without Tenant's fault,
                  Landlord shall repair the damage with reasonable dispatch, and
                  if the damage has rendered the Leased Premises wholly or
                  partially untenable, the Rent shall be apportioned until the
                  damage is repaired. In determining what constitutes reasonable
                  dispatch, consideration shall be given to delays caused by
                  strikes, adjustment of insurance, and other causes beyond the
                  Landlord's control.

20.               Default. Each of the following shall constitute an Event of
                  Default ("Event of Default"):
A.                Failure to Pay Annual Base Rent.  Tenant fails to pay any
                  installment of Base Rent within ten (10) days after such
                  installment is due and payable;  or

B.                Other Payment Failure. Tenant fails to pay any utility,
                  Additional Rent or other charge or payment due or payable by
                  Tenant under this Lease on any day upon which the same shall
                  be due and payable, if such failure continues for ten (10)
                  days after receipt of written notice that he same is due and
                  payable; or

C.                Other Violations. Tenant defaults in the performance of any
                  other obligation, covenant or agreement of Tenant to be
                  performed or observed under this Lease, and such default
                  continues and is not cured by Tenant within ten (10) days
                  after Landlord has given to Tenant a written notice specifying
                  the same (provided that if such default cannot reasonably be
                  cured within 10 days, no Event of Default shall occur if
                  Tenant initiates such cure within the 10 day period and
                  diligently pursues it to completion in a reasonable time
                  thereafter), but in no event shall such period exceed the
                  lesser of (i) an additional sixty (60) days or (ii) the
                  remaining term of the Lease; or

D.                Occupancy. Tenant fails to assume occupancy of the Leased
                  Premises, to open its business or to operate its business in
                  the Leased Premises pursuant to the provisions of this Lease.

E.                Judgment. Any execution or attachment is issued against Tenant
                  or any of Tenant's property and is not discharged or vacated
                  within the twenty (20) days after issuance thereof.

F.                Insolvency. Tenant makes an assignment for the benefit of
                  creditors or becomes a party or subject to any liquidation or
                  dissolution action or proceeding, or the institution of any
                  bankruptcy, reorganization, insolvency or other proceeding for
                  the relief of financially distressed debtors with respect to
                  Tenant, or a receiver, liquidator, custodian or trustee being
                  appointed for Tenant or a substantial part of Tenant's assets
                  and, if any of the same occur involuntarily, the same is not
                  dismissed or discharged within thirty (30) days; or the entry
                  of an order or relief against Tenant under Title II of the
                  United States Code entitled "Bankruptcy"; or Tenant taking any
                  action to effect, or which indicates Tenant's or acquiescence
                  in, any of the foregoing.

21.               Landlord's Rights upon Default. Upon the occurrence of an
                  Event of Default, the Landlord may exercise any or all of its
                  rights under this Lease, in addition to those it may have at
                  law or in equity.
         A. Termination. Upon the occurrence of any one or more of such Event of
Default, Landlord may serve upon Tenant a notice that this Lease will terminate
on a date to be specified therein, and Tenant shall have no right to avoid the
cancellation or termination by payment of any sum due or by other performance of
any condition, term or covenant broken, and notwithstanding any statute, rule or
law, or decision of any court to the contrary, Tenant shall remain liable as set
forth hereinafter for rent and any other charges due Landlord under this Lease,
plus the costs incurred by Landlord to prepare leased Premises for a new Tenant.

         B. Right of Possession. Upon any Event of Default, and if the notice
         provided for in Paragraph 21 A above shall have been given and this
         Lease shall be terminated; or if the Leased Premises becomes vacant or
         deserted; then in all or any of such events, in addition to and not in
         lieu of, all other remedies of Landlord, Landlord may without notice
         terminate all services (including, but not limited to, the furnishing
         of utilities) and re-enter the Leased Premises, either by force or
         otherwise, and/or by summary proceedings or otherwise disposes Tenant,
         and remove its effects and repossess and enjoy the Leased Premises,
         together with all alterations, additions and improvements, all without
         being liable to prosecution or damages therefore.

22.      Additional Remedies of Landlord.
         A.       In the event of any Event of Default, re-entry, termination
                  and/or dispossession by summary proceedings or
                  otherwise, in addition to, and not in lieu of, all
                  other remedies which Landlord has under this Lease, at law or
                  in equity; (1) the Base Rent, Common Area Maintenance
                  Rent and all Additional Rent shall become due thereupon and
                  be paid up to the time of such re-entry, dispossession
                  and/or expiration; and (2) Landlord may relet the Leased
                  Premises or any part of parts thereof, either in the name
                  of Landlord or otherwise for a term of rental which may
                  at Landlord's option be less than or exceed the period
                  which would otherwise have constituted the balance of the
                  term of this Lease, and at such rental or rentals and
                  upon such other terms and conditions as Landlord, in its
                  sole discretion, may deem advisable.  Landlord may
                  make such alterations and repairs as Landlord deems necessary
                  in order to relet the Leased Premises upon each such
                  reletting all rentals received by Landlord from such
                  reletting shall be applied, first, to the payment of
                  any costs and expenses of such reletting, including
                  brokerage fees, attorneys' fees and costs of such
                  alterations and repairs; second, to the payment of any
                  indebtedness other than rent due hereunder from Tenant
                  to Landlord; third, to the payment of rent due and unpaid
                  hereunder; and the residue, if any, shall be held by
                  Landlord and applied in payment of future rent as the same
                  may become due and payable hereunder.  If such rents
                  received from such reletting during any month are less than
                  that to be paid during that month by Tenant hereunder,
                  Tenant shall pay any such deficiency to Landlord. Such
                  deficiency shall be calculated and paid monthly.
                  No such reentry or taking possession of the Leased Premises by
                  Landlord shall be construed as an election on its part to
                  terminate this Lease unless a written notice of such
                  intention be given to Tenant or unless the termination
                  thereof be decreed by a court of competent jurisdiction.
                  Notwithstanding any such reletting without termination,
                  Landlord may at any time thereafter elect to terminate
                  this Lease for such previous breach.

         B.       Landlord shall have the election, in place and instead of
                  holding Tenant so liable, to recover against Tenant, as
                  liquidated damages for loss of the bargain and not as a
                  penalty, a sum equal to the monthly amount of Base Rent and
                  all Additional Rent multiplied by the number of months and
                  fractional months which would have constituted the balance of
                  the term (or such lesser time period specified by Landlord),
                  together with costs and reasonable attorney's fees. Actions to
                  collect amounts due by Tenant may be brought from time to
                  time, on one or more occasions, without the necessity of
                  Landlord's waiting until the expiration of the Lease term.

D.                Tenant hereby expressly waives the service of notice of
                  intention to re-enter or to institute legal proceedings
                  granted by or under any present or future laws in the event of
                  Tenant being evicted or disposed for any cause, or in any
                  event of Landlord obtaining possession of the Leased Premises
                  by reason of the violation by Tenant of any of the covenants
                  and conditions of this Lease or otherwise. The words
                  "re-enter" and "re-entry" as used in this Lease are not
                  restricted to their technical legal meaning.

23.      CONFESSION OF JUDGMENT. (THIS CLAUSE SHALL APPLY PROVIDED TENANT'S
                                 ------------------------------------------
         DEFAULT IS NOT DUE TO LANDLORD'S FAILURE TO PERFORM
         ---------------------------------------------------
         UNDER THE TERMS OF THE LEASE.)  IF THE BASE RENT, ADDITIONAL RENT
         -----------------------------
         AND/OR OTHER CHARGES HEREBY RESERVED AS RENT SHALL
         REMAIN UNPAID FOR A PERIOD OF TEN (10) DAYS AFTER THE DAY WHEN
         THE SAME SHOULD BE PAID IN ACCORDANCE WITH THE TERMS OF
         THIS LEASE, OR IF THE TENANT DEFAULTS OR BREACHES ANY OF THE TERMS,
         CONDITIONS OR COVENANTS OF THIS LEASE, AND FAILS TO
         CURE SUCH DEFAULT OR BREACH WITHIN THE APPLICABLE PERIOD OF TIME,
         PROVIDED PRIOR WRITTEN NOTICE IS PROVIDED TO THE
         TENANT, THE TENANT HEREBY GRANTS THE FOLLOWING WARRANT OF ATTORNEY:
         TENANT HEREBY IRREVOCABLY AUTHORIZES AND EMPOWERS ANY
         PROTHONOTARY, CLERK OF COURT OR ATTORNEY OF ANY COURT OF RECORD,
         TO APPEAR FOR THE TENANT IN ANY AND ALL ACTIONS WHICH
         MAY BE BROUGHT FOR SUCH RENT AND/OR CHARGES AND TO CONFESS AND
         ENTER JUDGMENT AGAINST THE TENANT AND IN FAVOR OF
         LANDLORD, ITS SUCCESSORS OR ASSIGNS, FOR ALL OF ANY PART OF THE
         BASE RENT OR ADDITIONAL RENT SPECIFIED IN THIS LEASE AND
         THEN UNPAID INCLUDING, AT THE OPTION OF LANDLORD, THE RENT FOR THE
         ENTIRE UNEXPIRED BALANCE OF THE TERM OF THIS LEASE,
         AND/OR OTHER CHARGES, COSTS AND EXPENSES RESERVED AS RENT OR AGREED
         TO BE PAID BY THE TENANT AND FOR INTEREST AND COSTS
         TOGETHER WITH REASONABLE ATTORNEY'S FEES.  SUCH AUTHORITY SHALL NOT
         BE EXHAUSTED BY ONE EXERCISE THEREOF, AND JUDGMENT
         MAY BE CONFESSED AS AFORESAID FROM TIME TO TIME AS OFTEN AS ANY
         OF THE SAID RENT AND/OR CHARGES RESERVED AS RENT SHALL
         FALL DUE OR BE IN ARREARS. THIS PROVISION SHALL BE ENFORCEABLE
         ONLY PURSUANT TO LEGAL AUTHORITY EXISTING AT THE TIME OF
         SUCH CONFESSION AND SHALL OTHERWISE NOT INVALIDATE THE REMAINING
         TERMS AND CONDITIONS OF THIS LEASE AGREEMENT.  TENANT
         RELEASES AND AGREES TO RELEASE LANDLORD, AND ANY AFOREMENTIONED
         ATTORNEY, FROM ALL ERRORS AND DEFECTS WHATSOEVER OF A
         PROCEDURAL NATURE IN ENTERING SUCH JUDGMENT OR IN CAUSING SUCH
         WRIT OR PROCESS TO BE ISSUED OR IN ANY PROCEEDING THEREON
         OR CONCERNING THE SAME.

                                Tenant initials

24.      Care and Operation of Premises.
A.            The Leased Premises, including Tenant's windows and signs, shall
              be kept neat, clean and in good repair and order by Tenant at
              Tenant's expense. Tenant shall store all of Tenant's trash,
              garbage, and other refuse in suitable receptacles within the
              Leased Premises and shall be responsible for the removal and
              disposition of refuse from the Leased Premises to proper container
              areas provided by Landlord.

         B.       Tenant shall not cause or permit any unusual or objectionable
                  noises or odors to emanate from the Leased Premises, or permit
                  the playing or making of any music, sound or advertising
                  matter which can be heard outside of the Leased Premises.
                  Tenant agrees that no noxious fumes or hazardous wastes or
                  chemicals will be used on or emitted from the Leased Premises
                  in the daily conduct of the Tenant's business.

         C.       Tenant shall not obstruct, encumber or use for any purposes,
                  other than ingress or egress to and from the Leased Premises,
                  the sidewalks in front of or abutting any part of the Leased
                  Premises or the entrances or vestibules thereof and no selling
                  shall be conducted or products displayed by Tenant anywhere
                  within the Union Square Condominium outside the Leased
                  Premises unless the same shall be expressly permitted by this
                  Lease.

25.      Gross Floor Area. For the purpose of this Lease, "gross floor area"
         shall be deemed to mean the area within the exterior faces of the
         exterior walls (except party walls and walls between spaces occupied by
         two or more separate occupants, in both of which cases the center of
         the wall in question shall be used instead of the exterior face
         thereof) of all floors, without deduction or exclusion for any space
         occupied by or used for columns or other interior construction or
         equipment servicing the Leased Premises, and any common hallway
         directly behind leased area.

26. Signs. Tenant shall post no signs unless specifically approved by Landlord.
All signs shall
         conform to all zoning codes and of such size, color, design and
         character and in such location as Landlord shall approve in writing. No
         other signs, lettering or other forms of inscription or advertising
         devices shall be displayed on the exterior of the Leased Premises or on
         the inner or on the outer face of the windows, entrances, or doors,
         without prior written approval of Landlord. Landlord reserves to itself
         the exclusive right to the use of the roof of the Building for all
         purposes.

27.      Common Areas.
A.       Landlord reserves the right to make changes, additions, alterations or
         improvements in or to the common areas of the Building; provided,
         however that there shall thereby be caused no unreasonable obstruction
         of Tenant's right of access to the Leased Premises, or any unreasonable
         interference with Tenant's use of the Leased Premises, or any reduction
         in the minimum required size of such common areas.

B.       Tenant will at its expense, keep the areas immediately in front of its
         doors free of debris, et cetera.

28.      Rules and Regulations. Tenant, and its servants, employees, agents,
         licensees and concessionaires shall observe faithfully and comply with
         such reasonable rules and regulations existing for the property or
         those which may be from time to time adopted by the Landlord governing
         the use of the common areas. The Landlord reserves the right from time
         to time to make reasonable changes in such rules and regulations and to
         make reasonable changes, additions, alterations or improvements in or
         to such common areas. Tenant further agrees that it is bound by all of
         the covenants, terms, conditions, requirements and rules and
         regulations in the Declaration of Condominium, Bylaws, and Rules and
         Regulations of Union Square Condominium.

29.      Extraneous Warranties and Representations. Landlord or Landlord's
         agents have made no representations, warranties or promises with
         respect to the Union Square Condominium, the Building, or the Leased
         Premises, except as herein expressly set forth.

30.      Landlord's Right to Enter. Landlord may, at reasonable times, and with
         prior notice (except in case of emergency) enter the Leased Premises to
         inspect it, to make repairs or alterations, and to show it to potential
         buyers, lenders or tenants.

31.      Surrender upon Termination. At the end of the Lease term Tenant shall
         peaceably surrender the Leased Premises to Landlord in as good
         condition as it was in at the beginning of the term, reasonable use and
         wear excepted.

32.      Quiet Enjoyment. Landlord agrees that if Tenant shall pay the rent as
         aforesaid and perform the covenants and agreements herein contained on
         its part to be performed, Tenant shall peaceably hold and enjoy the
         said Leased Premises without hindrance or interruption by Landlord or
         by any other person or persons acting under or through Landlord.

33.      No Smoking Building. The Building in which the Leased Premises is
         located is a non- smoking building and Tenant agrees that neither
         Tenant, his employees, guests or clients will be allowed to smoke in
         the Building.

34.      Subordination. This Lease, and the Tenant's leasehold interest, is and
         shall be subordinate, subject and inferior to any and all mortgages,
         liens, security interests and encumbrances now and thereafter placed on
         the Leased Premises by Landlord, any and all extensions, renewals,
         consolidations, assignments and refinancings (collectively,
         "Mortgages") of such mortgages, liens, security interests and
         encumbrances and all advances paid under such mortgages. In the case
         that Landlord's interest under the Mortgage shall terminate for any
         reason and if the holder of any such Mortgage ("Mortgagee") or if the
         grantee of a deed in lieu of foreclosure, or if the purchaser at any
         foreclosure sale or at any sale under a power of sale contained in any
         such Mortgage shall at its sole option so request, Tenant shall attorn
         to, and recognize such Mortgagee, grantee or purchaser, as the case may
         be, as Landlord under this Lease for the balance then remaining of the
         term of this Lease, subject to all terms of this Lease. The aforesaid
         provisions shall be self operative and no further instrument or
         document shall be necessary unless required by any such Mortgagee,
         grantee or purchaser. Notwithstanding anything to the contrary set
         forth above, any Mortgagee may at any time subordinate its Mortgage to
         this Lease, without Tenant's consent, by execution of a written
         document subordinating such Mortgage to this Lease, and thereupon this
         Lease shall be deemed prior to such Mortgage.

35.      Execution of Estoppel Certificate. At any time Landlord or any
         Mortgagee, can require Tenant, within 20 days of the date of such
         written request, to execute and deliver to Landlord and/or such
         Mortgagee, without charge and in a form satisfactory to Landlord and/or
         such Mortgagee, a written statement: (a) ratifying this Lease; (b)
         confirming the commencement and expiration dates of the term of this
         lease; (c) certifying that Tenant is in occupancy of the Leased
         Premises, and that the Lease is in full force and effect and has not
         been modified, assigned, supplemented or amended except by such
         writings as shall be
         stated; (d) certifying that all conditions and agreements under this
Lease to be satisfied or performed by Landlord have been satisfied and performed
except as shall be stated; (e) certifying that Landlord is not in default under
the Lease and thereafter no defenses or offsets against the enforcement of this
Lease by Landlord, or stating the defaults and/or defenses claim by Tenant; (f)
reciting the amount of advance rent, if any, paid by Tenant and the date to
which such rent has been paid; (g) reciting the amount of Security Deposited
held by Landlord, if any, and (h) any other information which Landlord or the
Mortgagee shall reasonably require.

36.      Miscellaneous Terms:
         A.       Notices. Any notice, statement, demand or other communication
                  by one party to the other, shall be given by personal
                  delivery, by mailing the same by certified mail, return
                  receipt requested, postage prepaid or by private delivery
                  service guaranteeing overnight delivery, addressed to the
                  Tenant at the premises, or to the Landlord at the address set
                  forth above, or by facsimile transmission to the fax numbers
                  set forth above. The date of notice shall be deemed to be the
                  date personally delivered, the date fax, two (2) business days
                  after deposit in the United States mail, or one (1) business
                  day after deposited with overnight delivery service.

         B.       Severability. If any clause or provision herein shall be
                  adjudged invalid or unenforceable by a court of competent
                  jurisdiction or by operation of any applicable law, it shall
                  not affect the validity of any other clause or provision,
                  which shall remain in full force and effect.

         C.       Waiver. The failure of either party to enforce any of the
                  provisions of this lease shall not be considered a waiver of
                  that provision or the right of the party to thereafter enforce
                  the provision .

         D.       Waiver of Jury Trial. Landlord and Tenant do hereby waive the
                  right of Jury Trial in any action arising as a result of any
                  claim made under this Lease or in any other ways otherwise in
                  connection herewith. The parties understand that this will
                  result in any dispute not heard by a jury but will be heard by
                  a Judge or other proper party as the case may be.

         E.       Complete Agreement. This Lease constitutes the entire
                  understanding of the parties with respect to the subject
                  matter hereof and may not be modified except by an instrument
                  in writing and signed by the parties.

         F.       Brokers.  Tenant represents and warrants to Landlord that
                  Tenant has had no dealing, negotiations or
                  consultations with respect to the Leased Premises or
                  this transaction with any broker or finder and that no
                  broker or finder called the Leased Premises or any other
                  space in the Union Square Condominium to Tenant's
                  attention.  In the event that any broker or finder claims
                  to have submitted the Leased Premises or any other
                  space in the Union Square Condominium to Tenant, to
                  have induced Tenant to lease the Leased Premises or to have
                  taken part with Tenant or any of its principals, agents
                  or employees in any dealings, negotiations or
                  consultations with respect to the Leased Premises or
                  this transaction, Tenant shall be responsible for and shall
                  defend, indemnify and save Landlord harmless from and
                  against all costs, fees (including, without limitation,
                  reasonable attorney's fees), expenses, liabilities and
                  claims incurred or suffered by Landlord as a result
                  thereof.

37. Lease Documents. In addition to the Commercial Lease, the following are
attached to the Lease and are hereby incorporated in and made part of the Lease
as though fully set forth at length in the Lease: Exhibit A (Building Plan),
Exhibit B (Specifications for Union Square) and Exhibit C (Declaration of
Condominium Use Restrictions) and are collectively referred to as the "Lease
Agreement" or "Lease".

38. First Right of Refusal. Tenant shall have the First Right of Refusal to
lease contiguous space, upon availability, upon the same terms and at the same
Base Rent and Common Area Maintenance Rent rate as Tenant's then current rate.


         IN WITNESS WHEREOF the parties intending to be legally bound, have set
their hands and seals on this day of , 2003.

                                             LANDLORD:
                                             UNION SQUARE, LIMITED PARTNERSHIP


                                            Joanne W. Lutostansky
- -------------------------------             --------------------------------
Witness                                     By:  George E. Michael, Partner


                                            TENANT:
                                            PROTALEX, INC.

                                            Steven Kane
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Witness                                     By:  Steven Kane, President, CEO