John Hancock Variable Series Trust I Michele G. Van Leer Chairman and Chief Executive Officer [GRAPHIC OMITTED] April 30, 2001 State Street Bank and Trust Company P.O. Box 9111 Boston, MA 02209-9111 Attention: William Marvin Re: Amended and Restated Custodian Agreement dated as of January 30, 1995, as amended ---------------------------------------- Gentlemen: This letter will memorialize our mutual agreement to amend the above-referenced Custodian Agreement, effective as of May 1, 2001, to reflect the new Health Sciences Fund of the John Hancock Variable Series Trust I. We have also updated the list of current sub-advisers to all Funds. Please substitute copies of the attached Appendix A for the old copies of Appendix A in your files. Kindly acknowledge receipt of this letter and the attachment, and your agreement with the terms hereof, by signing and returning the duplicate of this letter. Thank you. Sincerely, JOHN HANCOCK VARIABLE SERIES TRUST I /s/Michele G. Van Leer ---------------------- Chairman and CEO Received and agreed to: STATE STREET BANK AND TRUST COMPANY By: ------------------------------------------------ Name: ---------------------------------------------- Title: --------------------------------------------- APPENDIX A CUSTODIAL AGREEMENT (As of May 1, 2001) Name of Fund Fund Sub-Manager(s) ------------ ------------------- 1. International Equity Index Independence Investment LLC 2. Small/Mid Cap Growth Wellington Management Company, LLP 3. Small Cap Growth John Hancock Advisers, Inc. 4. Small Cap Equity (formerly "Small Cap Capital Guardian Trust Company. Value") 5. Mid Cap Growth Janus Capital Corporation 6. Large/Mid Cap Value II ( formerly "Mid Cap Wellington Management Company, LLP Value") 7. Global Balanced Capital Guardian Trust Company 8. International Opportunities T. Rowe Price International, Inc. 9. Large Cap Value T. Rowe Price Associates, Inc. 10. Global Bond Capital Guardian Trust Company 11. Equity Index SSgA Funds Management, Inc. 12. Managed Independence Investment LLC. and Capital Guardian Trust Company 13. Money Market Wellington Management Company, LLP 14. Large Cap Growth Independence Investment LLC 15. Growth and Income Independence Investment LLC and Putnam Investment Management LLC 16. Real Estate Equity Independence Investment LLC and Morgan Stanley Dean Witter Investment Management Inc. 17. Short-Term Bond Independence Investment LLC 18. Active Bond John Hancock Advisers, Inc. 19. Small/Mid Cap CORE Goldman Sachs Asset Management (a division of Goldman, Sachs & Co.) 20. High Yield Bond Wellington Management Company, LLP 21. Bond Index Mellon Bond Associates, LLP 22. Emerging Markets Equity Morgan Stanley Dean Witter Investment Management Inc. 23. Large Cap Aggressive Growth Alliance Capital Management L.P. 24. Small Cap Value (formerly "Small/Mid Cap T. Rowe Price Associates, Inc. Value") 25. Large Cap Value CORE Goldman Sachs Asset Management (a division of Goldman, Sachs & Co.) 26. International Equity Goldman Sachs Asset Management (a division of Goldman, Sachs & Co.) 27. Aggressive Balanced Independence Investment LLC 28. Mid Cap Blend Independence Investment LLC 29. Fundamental Growth (formerly "Fundamental Putnam Investment Management LLC Mid Cap Growth") 30. Large/Mid Cap Value Wellington Management Company, LLP 31. Large Cap Value CORE II (formerly Goldman Sachs Asset Management (a division of "American Leaders Large Cap Value") Goldman, Sachs & Co.) 32. Active Bond II ( formerly "Core Bond") John Hancock Advisers, Inc. 33. Health Sciences Putnam Investment Management LLC John Hancock Variable Series Trust I Michele G. Van Leer Chairman and Chief Executive Officer [GRAPHIC OMITTED] April 30, 2001 State Street Bank and Trust Company P.O. Box 9111 Boston, MA 02209-9111 Attention: Ronald E. Logue John Hancock Life Insurance Company John Hancock Place Boston, MA 02116 Attention: Thomas J. Lee Re: Sub-Administration Agreement dated as of October 1, 1996, as amended --------------------------------------- Gentlemen: This letter will memorialize our mutual agreement to amend the above-referenced Sub-Administration Agreement, effective as of May 1, 2001, to reflect the new Health Sciences Fund of the John Hancock Variable Series Trust I. Attached is a revised copy of Schedule A to the Sub-Administration Agreement which reflects all of the Funds that are now subject to the Sub-Administration Agreement. Please substitute copies of the attached Schedule A for the old copies of Schedule A in your files. Kindly acknowledge receipt of this letter and the attachment, and your agreement with the terms hereof, by signing and returning the duplicate of this letter. Thank you. Sincerely, JOHN HANCOCK VARIABLE SERIES TRUST I /s/Michele G. Van Leer ---------------------- Chairman and CEO Received and agreed to: JOHN HANCOCK LIFE INSURANCE COMPANY By: ------------------------------------------------ Name: ---------------------------------------------- Title: --------------------------------------------- STATE STREET BANK AND TRUST COMPANY By: ------------------------------------------------ Name: ---------------------------------------------- Title: --------------------------------------------- SCHEDULE A Sub-Administration Agreement Listing of Investment Funds By Fund (As of May 1, 2001) 1. John Hancock Variable Series Trust I: International Equity Index 2. John Hancock Variable Series Trust I: Small/Mid Cap Growth 3. John Hancock Variable Series Trust I: Small Cap Growth 4. John Hancock Variable Series Trust I: Small Cap Equity (1) 5. John Hancock Variable Series Trust I: Mid Cap Growth 6. John Hancock Variable Series Trust I: Large/Mid Cap Value II (2) 7. John Hancock Variable Series Trust I: Global Balanced 8. John Hancock Variable Series Trust I: International Opportunities 9. John Hancock Variable Series Trust I: Large Cap Value 10. John Hancock Variable Series Trust I: Global Bond 11. John Hancock Variable Series Trust I: Equity Index 12. John Hancock Variable Series Trust I: Managed 13. John Hancock Variable Series Trust I: Money Market 14. John Hancock Variable Series Trust I: Large Cap Growth 15. John Hancock Variable Series Trust I: Growth and Income 16. John Hancock Variable Series Trust I: Real Estate Equity 17. John Hancock Variable Series Trust I: Short Term Bond 18. John Hancock Variable Series Trust I: Active Bond 19. John Hancock Variable Series Trust I: Small/Mid Cap CORE 20. John Hancock Variable Series Trust I: High Yield Bond 21. John Hancock Variable Series Trust I: Bond Index 22. John Hancock Variable Series Trust I: Emerging Markets Equity 23. John Hancock Variable Series Trust I: Large Cap Aggressive Growth 24. John Hancock Variable Series Trust I: Small Cap Value (3) 25. John Hancock Variable Series Trust I: Large Cap Value CORE 26. John Hancock Variable Series Trust I: International Equity 27. John Hancock Variable Series Trust I: Aggressive Balanced 28. John Hancock Variable Series Trust I: Mid Cap Blend 29. John Hancock Variable Series Trust I: Fundamental Growth (4) 30. John Hancock Variable Series Trust I: Large/Mid Cap Value 31. John Hancock Variable Series Trust I: Large Cap Value CORE II (5) 32. John Hancock Variable Series Trust I: Active Bond II (6) 33. John Hancock Variable Series Trust I: Health Sciences (1) Formerly "Small Cap Value" (2) Formerly "Mid Cap Value" (3) Formerly "Small/Mid Cap Value" (4) Formerly "Fundamental Mid Cap Growth" (5) Formerly "American Leaders Large Cap Value" (6) Formerly "Core Bond"