EXHIBIT 16.1


LBB & ASSOCIATES LTD., LLP                          CERTIFIED PUBLIC ACCOUNTANTS


March 9, 2009

Securities and Exchange Commission
Washington, D.C. 20549

RE: Cytogenix,


         We have  read the  statements  that  Cytogenix,  Inc.  (the  "Company")
included  in Item 4.01 of the Form 8-K  report  it filed  regarding  the  recent
change of auditors_ We do not:agree  with the  following  statement  made by the
Company in paragraph 3 of Item 4.01:

         "LBB &  Associates  Ltd ,  LLP',s  report  on the  Company's  financial
statements fin- year ended December 31, 2007, did not contain  adverse  opinions
or  disclaimers  of  opinion,   nor  were  they  qualified  or  modified  as  to
uncertainty, audit scope or accounting principles"..

         Our report on the  Company's  financial  statements  for the year ended
December  31,  2007  was  modified  with an  explanatory  paragraph  emphasizing
substantial doubt about the Company's ability to continue as a going concern.

         Furthermore,  LBB & Associates Ltd, LLP wishes to further clarify that,
on March 2, 2009,  prior to our dismissal as auditors,  management of Cytogenix,
Inc,   was  informed  by  LBB  that,   due  to  firm  policy  and   independence
considerations,  LBB would not proceed with the current period audit  engagement
until  delinquent  fees  from  the  prior  year  audit  were  settled.  We  were
subsequently dismissed as auditors, and such fees have not been settled.

         We have no basis to agree or disagree with other  statements made under
Item 4.01.


                                                  Very truly yours.,


                                                  /s/ LBB & Associates Ltd., LLP
                                                      --------------------------
                                                      LBB & ASSOCIATES LTD., LLP





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