Exhibit 99.1


March 22, 2009



Lex Cowsert and the Board of Directors
CytoGenix, Inc.
3100 Wilcrest Drive, Ste. 140
Houston, TX 77042

         RE:  Letter of Resignation

Dear Lex,

     I am writing to inform you that I will be  resigning  from my  position  as
Vice President of Legal Affairs and Secretary,  effective today. Although I will
remain with the Company as a Consultant, I will be transferring all of my Patent
responsibilities to new patent counsel and will no longer act in the capacity as
corporate counsel for CytoGenix, Inc.

     As agreed, I will continue in an advisory capacity on an as needed basis so
that the Company can continue to move forward.  My best wishes go to you and the
remaining  members of the team in this  difficult  economic time. As you know, I
will do as much as is  feasibly  possible  to assist  your  efforts in  securing
financing and in pushing the science into the next developmental phase.

     I am  optimistic  that your  energy  and  vision  will turn this  situation
around.



                                                     All my best,


                                                     /s/ Cindee Ewell
                                                     ----------------
                                                     Cindee Ewell