United States
                       Securities and Exchange Commission
                             Washington, D.C. 20549


                         -------------------------------


                                    FORM 8-K


                                 CURRENT REPORT

     PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934

        Date of Report (Date of earliest event reported): May 6,  2009

                                 CytoGenix, Inc.
             (Exact name of registrant as specified in its charter)



                                     0-26807
                            (Commission File Number)

                Nevada                                        76-0484097
     ----------------------------                         ------------------
     (State or other jurisdiction                          (IRS Employer
         of incorporation)                                Identification No.)

3100 Wilcrest Drive, Suite 140, Houston, Texas              77042
(Address of principal executive offices)                    (Zip Code)

                                 (713) 789-0070  Registrant's  telephone number,
               including area code


|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))






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ITEM 5.02  DEPARTURE OF DIRECTORS OR CERTAIN  OFFICERS;  ELECTION OF  DIRECTORS;
APPOINTMENT OF CERTAIN OFFICERS; COMPENSATORY ARRANGEMENTS OF CERTAIN OFFICERS.


         On August 18 2008, the Company  received from Dr. Malcolm  Skolnick,  a
letter of  resignation  effective as of the August 18, 2008 meeting of the board
of directors.

         On April  24,  2009,  the  Company  executed  a  Settlement  Agreement,
Indemnification  and Mutual Release with Malcolm Skolnick,  the Company's former
Chairman  of the Board,  President  and Chief  Executive  Officer for the sum of
$10.00 and the intent to  negotiate a consulting  agreement.  Under the terms of
the Agreement all parties to the Agreement  agreed to dismiss any and all actual
and  potential  claims  that have been raised or which could have been raised at
the time of the execution of the Agreement.  A Copy of the Settlement Agreement,
Indemnification  and Mutual  Release is attached to this Current  Report on Form
8-K as an exhibit.


ITEM 9.01  FINANCIAL STATEMENTS AND EXHIBITS

    (c)  Exhibits


Exhibit No.               Description
- -----------               -----------

99.1           Settlement Agreement, Indemnification and MutualRelease






                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


     May 6, 2009                CytoGenix, Inc.

                                  By:  /s/  Randy Moseley
                                  ----------------------------------------------
                                  Randy Moseley, Principal Financial Officer





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