Exhibit (D)(2)

950 Page Mill Road
P O Box 10950
Palo Alto, CA 94303-0802
(650) 494-5300

July __, 1998

To All Class A Limited Partners of ALZA TTS Research Partners, Ltd:

I am pleased to send you the attached Notice of Limited Partners notifying you
that ALZA Development Corporation ("ADC") is exercising its option to acquire
all of the outstanding Class A and Class B limited partnership interests of ALZA
TTS Research Partners, Ltd. (the "Partnership"), and has established a closing
date of __________ for the purchase. As previously disclosed, the aggregate
purchase price for the Class A and Class B limited partners' interests is
$120,000,000 in cash, less all "Excess Cash" distributed to the limited partners
by the Partnership. Excess Cash distributed through June 29, 1998 was
$28,823,407.52. As a result, the purchase price is $91,176,592.48. Each Class A
limited partner (or its transferee) of record as of the closing date will
receive $27,216.21 per Unit. Each Unit was purchased in the original offering
for $5,000. NEITHER THE NOTICE TO LIMITED PARTNERS NOR THE CLOSING OF THE
PURCHASE REQUIRES YOU TO TAKE ANY ACTION IN ORDER TO RECEIVE THE PURCHASE PRICE
FOR YOUR UNITS.

While the tax consequences of receipt of the purchase price will vary for each
limited partner, the general federal income tax consequences associated with 
the purchase are described in the Notice to Limited Partners. In general, on 
the sale of any limited partnership interest, a portion of the purchase price in
excess of basis is treated as capital gain and a portion (reflecting "unrealized
receivables" of the partnership) is treated as ordinary income. However, due to
the Partnership's accrual method of accounting, the Partnership anticipates that
it will have no unrealized receivables. Instead, the limited partners of the
Partnership will have ordinary income from accrued royalties and this income
will be included in each limited partner's basis in its partnership interest, as
reflected on each partner's IRS Schedule K-1. Prior to the end of 1998, or early
next year, ADC will, on behalf of the Partnership, distribute to all limited
partners a final Schedule K-1. The Schedule K-1 will show tax information for
1998, including ordinary income, and the closing of each partners's capital
account. EACH PARTNER'S TAX SITUATION MAY BE DIFFERENT AND YOU SHOULD CONSULT
WITH YOUR OWN TAX ADVISOR.

We thank you again for your support and participation in ALZA TTS Research 
Partners, Ltd., a partnership that has been successful in fulfilling its goals
of generating substantial value for its limited partners and creating 
innovative and beneficial pharmaceutical products.

Sincerely,



David R. Hoffmann
President