Exhibit 10.1
MODIFICATION NO.1
TO
STEVENSON-WYDLER (15 USC 3710) COOPERATIVE RESEARCH AND
DEVELOPMENT AGREEMENT (hereinafter "CRADA") No. 04-CR-09
BETWEEN
Battelle Energy Alliance, LLC under its U.S. Department of Energy Contract
No. ED-AC07-05ID14517 (hereinafter "Contractor")
AND
Applied DNA Sciences, Inc. (hereinafter "Participant"),
hereinafter referred to singularly as "Party" and jointly as "Parties"
Whereas both Parties desire to modify CRADA No. 04-CR-09; the Parties hereby
agree to incorporate the following changes:
1. Replace Article III, Paragraph A with "The effective date of this CRADA
shall be the latter date of (1) the date on which it is signed by the last
of the Parties, (2) the date on which it is approved by DOE, or (3) the
date on which the advance funding referred to in Article III.B is received
by the Contractor. The work to be performed under this CRADA shall be
complete within three (3) years from the effective date.
2. Replace Article III, Paragraph B with "Participant's estimated contribution
is $50,000 funds-in and $0 in-kind for FT-04 and $1,701,216 funds-in and $0
in-kind for FY-05. There is no Government funding associated with this
CRADA.
3. Replace the Contractor information under Article XXVII: NOTICES as follows:
Agreements Administrator
Technology Transfer & Commercialization
Battelle Energy Alliance, LLC
2525 N. Fremont Ave.
P.O. Box 1625, MS 3805
Idaho Falls, ID 83415-3805
E-mail: agradmin@inl.gov
Phone: (208) 526-6141
Fax: (208) 526-0876
4. Add the following paragraph to Appendix A, "Statement of Work", paragraph
10 "Further develop and refine the selected applications:
Validate Biowell Embedded DNA Technology, including: 1) marker DNA &
primer/probe characterization, 2) unique DNA productions and embedding
methods assessment, validation replication, and enhancement, and 3)
embedding matrix material analysis, signature signal assessment and
stand-off detection methods. In addition, develop a new product application
including: 1) thread detection methods validation, RT-PCR methods
development and protocol standardization; 2) ink detection methods
validation, RT-PCR methods development and protocol standardization;
gasoline methods validation, RT-PCR methods development and protocol
standardization; and 4) explosive materials detection methods validation,
RT-PCR methods development and protocol standardization. Also develop a new
petroleum product application including stand-off sensing.
5. Delete the header "Timeline:" and associated table in the scope of work.
ACCEPTED TO AND AGREED TO:
FOR BATTELLE ENERGY ALLIANCE, LLC
BY: /s/ A. RAY BARNES
-----------------
PRINTED NAME: A. RAY BARNES
TITLE: Group Manager, Technology Transfer & Commercialization
DATE: March 24, 2005
FOR APPLIED DNA SCIENCES, INC.
BY: /s/ KARIN KLEMM
---------------
PRINTED NAME: Karim Klemm
TITLE: Chief Operating Officer/Chief Financial Officer
DATE: March 24, 2005