UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549

                                    FORM 8-K

                                 CURRENT REPORT

   Pursuant to Section 13 OR 15(d) of the Securities and Exchange Act of 1934

          Date of Report (Date of earliest reported): October 17, 2005

                                  CARDIMA, INC.


               (Exact name of registrant as specified in charter)



            Delaware                     000-22419               94-3177883
(State or Other Jurisdiction of   (Commission File Number)     (IRS Employer
 Incorporation or Organization)                             Identification No.)



                47266 Benicia Street, Fremont, California, 94538

               (Address of principal executive offices) (Zip Code)

       Registrant's telephone number, including area code: (510) 354-0300

                                   Copies to:

                            Richard A. Friedman, Esq.
                       Sichenzia Ross Friedman Ference LLP
                           1065 Avenue of the Americas
                            New York, New York 10018
                              Phone: (212) 930-9700
                               Fax: (212) 930-9725

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

Written  communications  pursuant to Rule 425 under the  Securities  Act (17 CFR
230.425)

Soliciting  material  pursuant to Rule  14a-12  under the  Exchange  Act (17 CFR
240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act
(17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act
(17 CFR 240.13e-4(c))

SECTION 4 - MATTERS RELATED TO ACCOUNTANTS AND FINANCIAL STATEMENTS



ITEM 4.01 CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT.

On October 17, 2005, BDO Seidman, LLP (the "Former Accountant")  resigned as the
independent registered public accounting firm for Cardima, Inc. (the "Company").
The Company  engaged  Marc Lumer & Company  (the "New  Accountant"),  as its new
independent  registered public accounting firm. The Company's decision to engage
the New Accountant was approved by its Board of Directors on October 18, 2005.

The reports of the Former Accountant on the financial  statements of the Company
for each of the two most recent fiscal years, did not contain an adverse opinion
or disclaimer  of opinion and was not  qualified or modified as to  uncertainty,
audit  scope or  accounting  principles  for the two most recent  fiscal  years,
except  that the Former  Accountant's  opinion  in its  report on the  Company's
financial statements for each of the last two fiscal years expressed substantial
doubt with respect to the Company's ability to continue as a going concern.

During the  Company's two most recent  fiscal years and the  subsequent  interim
period through the date of resignation,  there were no reportable  events as the
term is described in Item 304(a)(1)(iv) of Regulation S-B.

During the  Company's two most recent  fiscal years and the  subsequent  interim
period through the date of  resignation,  there were no  disagreements  with the
Former  Accountant  on  any  matters  of  accounting  principles  or  practices,
financial  statement  disclosure or auditing scope or procedure,  which,  if not
resolved to the  satisfaction of the Former  Accountant  would have caused it to
make reference to the subject matter of the disagreements in connection with its
reports on these financial statements for those periods.

The Company did not consult with the New Accountant regarding the application of
accounting principles to a specific  transaction,  either completed or proposed,
or the type of audit opinion that might be rendered on the  Company's  financial
statements,  and no written or oral advice was  provided  by the New  Accountant
that was a factor  considered  by the  Company in  reaching a decision as to the
accounting, auditing or financial reporting issues.

The Company has requested  that the Former  Accountant  furnish it with a letter
addressed to the Securities and Exchange  Commission  stating  whether it agrees
with the above  statements.  The requested letter is attached as Exhibit 16.1 to
this amended Form 8-K

Item 9.01 Financial Statements and Exhibits.

(a) Financial statements of business acquired.

Not applicable.

(b) Pro forma financial information.

Not applicable.

(c) Exhibits.



Exhibit
Number        Description

16.1          Letter from Former Accountant dated as of September 22, 2005.


                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                  CARDIMA, INC.





Date: October 21, 2005           By: /s/ Gabriel B. Vegh
                                     -------------------
                                  Name:   Gabriel B. Vegh
                                  Chief Executive Officer,
                                  Chief Financial Officer