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                          ADVANCED VIRAL RESEARCH CORP.
                                   $3,000,000
                            7% CONVERTIBLE DEBENTURE
                               DUE AUGUST 30, 2007
                              WARRANTS TO PURCHASE
          1,800,000 SHARES OF COMMON STOCK, PAR VALUE $.00001 PER SHARE







                               PURCHASE AGREEMENT
                            DATED SEPTEMBER 26, 1997










                          SECURITIES PURCHASE AGREEMENT










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                                TABLE OF CONTENTS
                                                                           Page

ARTICLE I
AUTHORIZATION OF THE SECURITIES............................................  1

ARTICLE II
SALE AND PURCHASE OF THE SECURITIES; CLOSING...............................  1
          2.1.        Sale and Purchase of the Securities..................  1
          2.2.        Closing..............................................  1

ARTICLE III
REPRESENTATIONS AND WARRANTIES OF THE PURCHASER............................  2
          3.1.        Offshore Transaction.................................  2
          3.2.        Beneficial Owner.....................................  2
          3.3.        Directed Selling Efforts.............................  3
          3.4.        Short Position.......................................  3
          3.5.        Independent Investigation............................  3
          3.6.        No Government Recommendation or Approval.............  3
          3.7.        Further Limitations on Disposition...................  3
          3.8.        Legal Representation.................................  4


ARTICLE IV
REPRESENTATIONS AND WARRANTIES OF THE COMPANY..............................  4
          4.1.        Organization and Existence, etc......................  4
          4.2.        Subsidiaries and Affiliates..........................  4
          4.3.        Capitalization.......................................  4
          4.4.        Authorization........................................  5
          4.5.        Binding Obligations; No Material Adverse
                      Contracts, etc.......................................  5
          4.6.        Financial Information................................  5
          4.7.        Compliance with Instruments, etc.....................  5
          4.8.        Litigation...........................................  6
          4.9.        Offering.............................................  6
          4.10.             Permits; Governmental and Other Approvals......  6
          4.11.             Reporting Company Status.......................  6
          4.12.       Offshore Transaction.................................  6
          4.13.       Prearranged Sale.....................................  7
          4.14.       No Directed Selling Efforts..........................  7
          4.15.             Copyrights, Trademarks and Patents.............  7
          4.16.             No Relationship Between Parties................  7
          4.17.             Other Material Contracts.......................  7
          4.18.             Disclosure.....................................  7


                                        i




ARTICLE V
CONDITIONS TO CLOSING OF THE PURCHASER.....................................  7
          5.1.        Representations and Warranties Correct...............  7
          5.2.        Performance..........................................  8
          5.3.        No Impediments.......................................  8
          5.4.        Other Agreements.....................................  8
          5.5.        Legal Investment.....................................  8
          5.6.        Due Diligence Investigation..........................  8
          5.7.        Proceedings and Other Documents......................  8

ARTICLE VI
CONDITIONS TO CLOSING OF THE COMPANY.......................................  8
          6.1.        Representations......................................  8
          6.2.        Legal Investment.....................................  9
          6.3.        Payment of Purchase Price............................  9

ARTICLE VII
OPTIONAL PREPAYMENTS.......................................................  9
          7.1.        Optional Prepayments.................................  9
          7.2.        Notice of Prepayment.................................  9
          7.3.        Exercise of Conversion Privilege Upon
                      Receipt of Prepayment Notice.........................  9

ARTICLE VIII
AFFIRMATIVE COVENANTS......................................................  9
          8.1.        Maintenance of Corporate Existence,
                      Properties and Leases; Taxes; Insurance.............. 10
          8.2.        Basic Financial Information.......................... 11
          8.3.        Notice of Adverse Change............................. 11
          8.4.        Compliance With Agreements; Compliance With Laws..... 12
          8.5.        Protection of Licenses, etc.......................... 12
          8.6.        Accounts and Records; Inspections.................... 12
          8.7.        NASDAQ or American Stock Exchange Listing............ 13
          8.8.        Reverse Stock Split.................................. 13
          8.9.        Further Assurances................................... 13

ARTICLE IX
EVENTS OF DEFAULTS......................................................... 13
          9.1.        Events of Default.................................... 13
          9.2.        Remedies............................................. 15
          9.3.        Enforcement.......................................... 16

ARTICLE X
AMENDMENT AND WAIVER....................................................... 16

ARTICLE XI
EXCHANGE AND REPLACEMENT OF DEBENTURES..................................... 17


                                       ii




ARTICLE XII
TRANSFER OF AND PAYMENT OF DEBENTURES...................................... 17
          12.1.       Notification of Proposed Sale........................ 17
          12.2.       Payment.............................................. 18


ARTICLE XIII
RIGHT OF FIRST REFUSAL..................................................... 18
          13.1.       Right of First Refusal............................... 18

ARTICLE XIV
MISCELLANEOUS.............................................................. 19
          14.1.       Governing Law........................................ 19
          14.2.       Survival............................................. 19
          14.3.       Successors and Assigns............................... 19
          14.4.       Entire Agreement..................................... 19
          14.5.       Notices, etc......................................... 20
          14.6.       Delays or Omissions.................................. 20
          14.7.       Rights; Severability................................. 20
          14.8.       Agent's Fees......................................... 21
          14.9.       Expenses............................................. 21
          14.10.      Litigation........................................... 21
          14.11.      Titles and Subtitles................................. 22
          14.12.      Counterparts......................................... 22



Exhibit A  -   Form of 7% Convertible Debenture
Exhibit B  -   Name and Address of Purchaser; Purchase Prices for Securities
Exhibit C  -   Schedule of Exceptions
Exhibit D  -   Form of Warrant


                                       iii






                                                              September 26, 1997


Agreement dated this 26th day of September,  1997 by and between  ADVANCED VIRAL
RESEARCH  CORP., a Delaware  corporation  (the  "Company"),  with offices at 200
Corporate   Boulevard   South,   Yonkers,   New   York   10701   and  RBB   Bank
Aktiengesellschaft  (the "Purchaser" or "you") with offices at Burgring 16, 8010
Graz, Austria.


                                    ARTICLE I

                         AUTHORIZATION OF THE SECURITIES

                  The Company  represents that it has taken all corporate action
necessary to authorize the issuance and sale of (a) its 7% Convertible Debenture
due August 30, 2007 in the principal amount of $3,000,000 (the  "Debenture") and
(b) warrants to purchase an aggregate of 1,800,000  shares of Common Stock,  par
value $.00001 per share ("Common Stock"),  of the Company (the "Warrants").  The
Debenture  and the  Warrants  (collectively,  the  "Securities")  are to be sold
pursuant to this  Agreement to you.  Interest on the Debenture is payable at the
rate of 7% per annum,  as more  particularly  specified in the form of Debenture
attached  hereto as Exhibit A. The  Debenture is  convertible  from time to time
into shares of Common Stock as provided therein.  For purposes of this Agreement
the term "Shares" shall mean the shares of Common Stock which may be issued upon
conversion of all or a portion of the principal  amount of the Debenture and the
shares of Common  Stock  that may be issued  from time to time  pursuant  to the
exercise of the Warrants.


                                   ARTICLE II

                  SALE AND PURCHASE OF THE SECURITIES; CLOSING

                  2.1. Sale and Purchase of the Securities. Subject to the terms
and  conditions  hereof and in reliance on the  representations  and  warranties
contained  herein,  or made pursuant hereto,  the Company will issue and sell to
the  Purchaser for its own account and for the accounts of its  participants  as
more  particularly  referred to below,  and the Purchaser will purchase from the
Company,  on the Closing Date  specified in Section 2.2, the  Securities for the
aggregate purchase price contemplated hereby.

                  2.2. Closing.  (a) The closing of the purchase and sale of the
Securities (the "Closing") shall be deemed to occur when this Agreement has been
executed  by both the  Company and the  Purchaser  and the Company has  received
payment for the Securities. Such date is herein called the "Closing Date."







                  (b) On  the  Closing  Date  there  will  be  delivered  to the
Purchaser (i) a Debenture  dated the Closing  Date, in the principal  amount set
forth opposite the Purchaser's  name on Exhibit B and (ii) warrant  certificates
in the forms of Exhibits  D-1, D-2 and D-3  registered in the  Purchaser's  name
representing  the right to  purchase  the  number of shares of Common  Stock set
forth opposite the Purchaser's name on Exhibit B. The foregoing Securities shall
be delivered by the Company, against delivery by the Purchaser to the Company of
an  unendorsed  certified or official  bank check drawn upon or issued by a bank
which is a member of the New York Clearinghouse for banks (or wire transfer) for
$3,000,000 payable to the order of the Company.


                                   ARTICLE III

                 REPRESENTATIONS AND WARRANTIES OF THE PURCHASER

                  3.1.  Offshore  Transaction.   The  Purchaser  represents  and
warrants to the Company that (a) the  Purchaser  is not a "U.S.  person" as that
term is defined in Rule 902(o) of Regulation S promulgated  by the United States
Securities and Exchange  Commission (the "Commission")  under the Securities Act
of  1933,  as  amended  (the  "Securities  Act");  (b) the  Purchaser  is not an
affiliate  of the  Company;  (c) at the  time of  execution  of this  Agreement,
Purchaser was outside the United States and no offer to purchase the  Securities
was made in the United  States;  (d) the  Purchaser  agrees  that all offers and
sales of the Securities  prior to the  expiration of a period  commencing on the
Closing Date and ending forty (40) days  thereafter  (the  "Restricted  Period")
shall not be made to U.S.  persons or for the account or benefit of U.S. persons
and shall  otherwise be made in compliance  with the provisions of Regulation S;
(e)  the  Purchaser  is  not a  distributor  or  dealer;  (f)  the  transactions
contemplated  hereby  (i) have not  been  and  will not be  pre-arranged  by the
Purchaser with a purchaser  located in the United States or a purchaser which is
a U.S. Person,  and (ii) are not and will not be part of a plan or scheme by the
Purchaser to evade the  registration  provisions of the Securities  Act; (g) the
Purchaser  shall  take  all  reasonable  steps to  ensure  its  compliance  with
Regulation  S and  shall  promptly  send to  each  purchaser  (x) who  acts as a
distributor,  underwriter,  dealer or other person  participating  pursuant to a
contractual  arrangement  in the  distribution  of the Securities or receiving a
selling  concession,  fee  or  other  remuneration  in  respect  of  any  of the
Securities,  or (y) who  purchases  prior to the  expiration  of the  Restricted
Period,  a  confirmation  or other  notice  to the  purchaser  stating  that the
purchaser  is  subject  to the same  restrictions  on  offers  and  sales as the
Purchaser pursuant to Section 903(c)(2)(iv) of Regulation S; and (h) none of the
Purchaser,  its  affiliates or persons acting on their behalf have conducted and
shall not conduct any "directed selling efforts" as that term is defined in Rule
902(b) of Regulation S; nor has the Purchaser,  its affiliates or persons acting
on their behalf conducted any general  solicitation to the offer and sale of any
of the Securities in the United States or elsewhere.

                  3.2.   Beneficial  Owner.  The  Purchaser  is  purchasing  the
Securities for its own account or for the account of beneficiaries  with respect
to the  Securities  and whom the Purchaser  has full  authority to bind, so that
each such beneficiary is bound hereby as if such beneficiary

                                        2





were a  direct  purchaser  hereunder  and all  representations,  warranties  and
agreements herein were made directly by such beneficiary.  Neither the Purchaser
nor any of such  beneficiaries  own, or upon completion of this transaction,  or
upon conversion of all or any part of the  Debentures,  will  beneficially  own,
more than 4.5% of the Common Stock of the Company.

                  3.3.  Directed Selling Efforts.  The Purchaser will not engage
in any activity for the purpose of, or that could reasonably be expected to have
the effect  of,  conditioning  the  market in the  United  States for any of the
Securities sold hereunder.  To the best knowledge of the Purchaser,  neither the
Company  nor any person  acting for the  Company  has  conducted  any  "directed
selling efforts" as that term is defined in Rule 902 of Regulation S.

                  3.4.  Short  Position.  Neither the  Purchaser  nor any of its
affiliates  will  directly  or  indirectly  maintain  any short  position in any
securities of the Company until after the end of the Restricted Period.

                  3.5. Independent  Investigation.  The Purchaser in electing to
purchase the Securities  hereunder,  has relied solely upon the  representations
and  warranties of the Company set forth in this  Agreement  and on  independent
investigation made by it and its representatives,  if any, and the Purchaser has
been given no oral or written  representations  or assurance from the Company or
any  representation  of the Company other than as set forth in this Agreement or
in a document executed by a duly authorized representative of the Company making
reference to this Agreement.

                  Prior to the commencement of the negotiations  concerning this
transaction,  the Purchaser had been a shareholder of the Company. In connection
therewith the Purchaser had conducted  such due diligence  investigations  as it
deemed prudent in connection with its investment decision.

                  3.6. No Government  Recommendation or Approval.  The Purchaser
understands that no United States federal or state agency,  or similar agency of
any other country,  has passed upon or made any recommendation or endorsement of
the Company, this transaction or the purchase of the Securities.

                  3.7.  Further  Limitations on Disposition.  Without in any way
limiting the  representations  set forth above, the Purchaser further agrees not
to make any  disposition  of all or any portion of the Securities (or the Common
Stock issuable upon the conversion or exercise thereof) unless and until:

                  (a) There is then in effect a Registration Statement under the
Securities Act covering such proposed  disposition and such  disposition is made
in accordance with such  Registration  Statement,  or the disposition is made in
compliance with Regulation S; or

                  (b) (1) The Purchaser,  through RBB Bank,  shall have notified
the Company of the proposed  disposition  and shall have  furnished  the Company
with a statement

                                        3





that it does  not  beneficially  own  more  than 5% of the  Common  Stock of the
Company  and is not an  officer  or  director  of the  Company  or (2)  if,  the
Purchaser  shall  have  furnished  the  Company  with  an  opinion  of  counsel,
reasonably  satisfactory to the Company,  that such disposition will not require
registration of such Securities under the Securities Act.

                  3.8. Legal  Representation.  The Purchaser has the opportunity
to be represented in this  transaction by counsel of its own choice and has been
so advised by counsel for the Company.


                                   ARTICLE IV

                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY

                  Other than as provided in the Schedule of Exceptions  attached
hereto as Exhibit C, the Company represents and warrants to you as follows:

                  4.1.  Organization  and  Existence,  etc.  The  Company  is  a
corporation  duly organized and validly  existing and in good standing under the
laws of its jurisdiction of incorporation, and has all requisite corporate power
and  authority  to carry on its  business as now  conducted  and  proposed to be
conducted;  the Company has all requisite corporate power and authority to enter
into this Agreement, to issue the Securities as contemplated herein and to carry
out  and  perform  its  obligations  under  the  terms  and  conditions  of this
Agreement.  The  Company  does not own or lease  any  property  or engage in any
activity in any jurisdiction which might require qualification to do business as
a foreign  corporation in such  jurisdiction and where the failure to so qualify
would have a material  adverse effect on the financial  condition of the Company
or subject  the Company to a material  liability.  To the extent the Company has
not  qualified  to do  business  in such  jurisdictions,  it has, as of the date
hereof,  prepared the necessary  applications  or documents to be filed with the
appropriate authorities in such jurisdictions to obtain such qualifications. The
Company  has  furnished  you with  true,  correct  and  complete  copies  of its
Certificate of Incorporation, By-laws and all amendments thereto to date.

                  4.2.  Subsidiaries and Affiliates.  Except as set forth in the
Schedule of Exceptions,  the Company has no subsidiaries  and does not, and upon
the Closing will not, own of record or beneficially  any capital stock or equity
interest or investment in any corporation, association or business entity.

                  4.3.     Capitalization.

                  (a) As of the date hereof,  the Company's  authorized  capital
stock consists of  1,000,000,000  shares of Common Stock,  par value $.00001 per
share, of which  277,190,373 are  outstanding,  30,982,400 of which are reserved
for  issuance to certain  persons  for the  purposes  stated in the  Schedule of
Exceptions,  60,000,000 of which have been reserved for issuance upon conversion
of the Debenture and 1,800,000 of which have been reserved for



                                        4





issuance upon exercise of the Warrants.  As of the date hereof, the Company does
not hold any shares of its capital stock in its treasury.

                  (b) All the issued and outstanding  shares of capital stock of
the Company shall, as of the Closing,  (i) have been duly authorized and validly
issued,  (ii) be fully  paid and  nonassessable,  and (iii)  have been  offered,
issued,  sold and delivered by the Company in compliance with applicable federal
and state securities laws. Other than as set forth in Section 4.3(a),  there are
no outstanding preemptive, conversion or other rights, options, warrants, calls,
agreements or commitments granted or issued by or binding upon the Company,  for
the purchase or acquisition of any shares of its capital stock.

                  4.4.  Authorization.  All corporate  action on the part of the
Company and the  directors  and  stockholders  of the Company  necessary for the
authorization,  execution,  delivery  and  performance  by the  Company  of this
Agreement and the transactions  contemplated  herein, and for the authorization,
issuance and delivery of the Securities,  has been taken or will have been taken
prior to the Closing.

                  4.5. Binding Obligations;  No Material Adverse Contracts, etc.
This Agreement is a valid and binding  obligation of the Company  enforceable in
accordance  with its terms.  The  execution,  delivery  and  performance  by the
Company  of this  Agreement  and  compliance  herewith  will not  result  in any
violation  of and will not  conflict  with,  or result in a breach of any of the
terms of, or constitute a default  under,  any provision of state or Federal law
to which the Company is subject,  the Certificate of Incorporation,  as amended,
or the  By-laws,  as  amended,  of the  Company,  or  any  mortgage,  indenture,
agreement,  instrument,  judgment,  decree,  order,  rule or regulation or other
restriction to which the Company is a party or by which it is bound,  or, result
in the creation of any mortgage, pledge, lien, encumbrance or charge upon any of
the properties or assets of the Company pursuant to any such term. Except as set
forth  herein no  stockholder  of the  Company  has or will have any  preemptive
rights or rights of first refusal by reason of the issuance of the Securities.

                  4.6. Financial  Information.  The Company has delivered to the
Purchaser true and complete copies of the financial  information  concerning the
Company  identified  in the Schedule of  Exceptions.  Except as may be indicated
thereon,  all  financial  statements  included in the  information  given to the
Purchaser fairly present the financial position and results of operations of the
Company  as at their  respective  dates  and for  their  respective  periods  in
conformity with generally accepted accounting  principles  consistently  applied
throughout the periods covered thereby. As of their respective dates the Company
had no liabilities or obligations of any nature (absolute,  accrued,  contingent
or otherwise) which would normally be reflected on a balance sheet and which are
not reflected on any balance sheet contained in the financial  information given
to the Purchaser or disclosed in accordance  with  generally  accepted  auditing
standards.

                  4.7. Compliance with Instruments,  etc. The Company is not (a)
in default past any grace, notice or cure period under any indenture,  agreement
or instrument to which it is a


                                        5





party  or by  which  it is  bound,  (b)  in  violation  of  its  Certificate  of
Incorporation,  By-laws or of any applicable law, (c) in default with respect to
any order,  writ,  injunction or decree of any court,  administrative  agency or
arbitrator, or (d) in default under any order, license,  regulation or demand of
any government agency, which default or violation would materially and adversely
affect the business, properties,  condition (financial or otherwise) or business
prospects of the Company.

                  4.8.  Litigation.  Except  as set  forth  in the  Schedule  of
Exceptions, there is no action, suit or proceeding pending, or, to the knowledge
of the Company, threatened, against the Company before any court, administrative
agency or  arbitrator  or any action,  suit or  proceeding  pending,  or, to the
knowledge  of the  Company,  threatened,  which  challenges  the validity of any
action taken or to be taken pursuant to or in connection  with this Agreement or
the issuance of the Securities.

                  4.9.  Offering.  Subject in part to the truth and  accuracy of
the  Purchaser's  representations  and the  compliance by the Purchaser with its
covenants  set forth in this  Agreement,  the offer,  sale and  issuance  of the
Securities as contemplated by this Agreement are not subject to the registration
requirements of the Securities Act of 1933, as amended (the  "Securities  Act"),
and the  Company,  or anyone  acting  on its  behalf,  will not take any  action
hereafter that would cause such registration requirements to be applicable.

                  4.10. Permits;  Governmental and Other Approvals.  The Company
possesses  such  franchises,  licenses,  permits  and  other  authority  as  are
necessary for the conduct of its business as now being conducted and proposed to
be conducted by the Company and the Company is not in default  under any of such
franchises,   licenses,  permits  or  other  authority.  No  approval,  consent,
authorization  or other  order of,  and no  designation,  filing,  registration,
qualification or recording with, any governmental  authority or any other person
or entity is required in connection with the Company's valid execution, delivery
and  performance  of this  Agreement  or the  offer,  issuance  and  sale of the
Securities  by the Company to the  Purchaser  or the  consummation  of any other
transaction contemplated on the part of the Company hereby.

                  4.11.  Reporting  Company Status.  The Company is a "Reporting
Issuer"  as  defined  by Rule 902 of  Regulation  S. The  Company  has filed all
material  required  to be filed  pursuant  to all  reporting  obligations  under
Section 15(d) of the Securities Exchange Act of 1934, as amended for a period of
at least  twelve  (12)  months  immediately  preceding  the offer or sale of the
Securities.

                  4.12.  Offshore  Transaction.  The  Company has not offered or
sold  the  Securities  to any  person  in the  United  States,  or,  to the best
knowledge of the Company,  any identifiable  groups of U.S.  citizens abroad, or
any U.S.  person as that term is  defined in  Regulation  S. At the time the buy
order of the Securities was originated the Company and/or its agents  reasonably
believed Purchaser was outside the United States and was not a U.S. Person.


                                        6





                  4.13.  Prearranged Sale. The Company and/or its agents believe
that the transaction  contemplated hereby has not been pre-arranged with a buyer
in the United States.

                  4.14.  No  Directed  Selling  Efforts.  The  Company  has  not
conducted any "directed  selling efforts" as that term is defined in Rule 902 of
Regulation S nor has Company conducted any general solicitation  relating to the
offer and sale of the Securities to persons resident within the United States or
any other U.S. person as that term is defined in Rule 902 of Regulation S.

                  4.15.  Copyrights,  Trademarks  and Patents.  Set forth in the
Schedule of Exceptions is a list of all the copyrights,  trademark registrations
and patents and applications therefor owned by the Company.

                  4.16. No Relationship  Between Parties.  The Company is not an
owner of any  shares of the stock of or equity  interest  in the  Purchaser.  No
officer,  director  or owner of any  shares of the stock of the  Company  or its
subsidiaries  or his close  relatives  is an officer or  director of or owns any
shares of the stock of or equity interest in the Purchaser.

                  4.17. Other Material  Contracts.  Set forth in the Schedule of
Exceptions is a list of contracts  material to the  operations of the Company to
which reference is not made elsewhere in this Article IV.

                  4.18.  Disclosure.  The information heretofore provided and to
be provided  pursuant to this  Agreement,  including the Schedules of Exceptions
and the Exhibits hereto, and each of the agreements, documents, certificates and
writings previously  delivered to the Purchaser or its  representatives,  do not
and will not contain any untrue statement of a material fact and do not and will
not omit to state a material  fact  required  to be stated  herein or therein or
necessary  in order to make the  statements  and writings  contained  herein and
therein not false or  misleading in the light of the  circumstances  under which
they  were  made.  To the  knowledge  of the  Company,  there  is no fact  which
materially adversely affects the business,  prospects or condition (financial or
otherwise) of the Company which has not been set forth herein.


                                    ARTICLE V

                     CONDITIONS TO CLOSING OF THE PURCHASER

                  The  obligation of the Purchaser to purchase the Securities at
the Closing is subject to the fulfillment to the Purchaser's  satisfaction on or
prior to the Closing Date of each of the following conditions,  any of which may
be waived by the Purchaser:

                  5.1.    Representations    and   Warranties    Correct.    The
representations and warranties in Article IV hereof shall be true and correct in
all material respects when made, and



                                        7





shall be true and correct in all material  respects on the Closing Date with the
same force and effect as if they had been made on and as of the Closing Date.

                  5.2.  Performance.  All  covenants,  agreements and conditions
contained in this  Agreement to be performed or complied  with by the Company on
or prior to the Closing Date shall have been  performed or complied  with by the
Company in all material respects.

                  5.3. No  Impediments.  Neither  the Company nor the  Purchaser
shall be subject to any order, decree or injunction of a court or administrative
agency of competent  jurisdiction which would impose any material  limitation on
the  ability of the  Purchaser  to  exercise  full  rights of  ownership  of the
Securities.

                  5.4.  Other  Agreements.  The Company shall have issued to the
Purchaser all of the Securities (including the Warrants in the forms of Exhibits
D-1, D-2 and D-3 attached hereto).

                  5.5.  Legal  Investment.  At  the  time  of the  Closing,  the
purchase of the Securities to be purchased by the Purchaser  hereunder  shall be
legally  permitted by all laws and  regulations  to which the  Purchaser and the
Company are subject.

                  5.6. Due Diligence Investigation. The Purchaser shall not have
discovered  any fact,  whether or not  reflected in the Schedule of  Exceptions,
which  in the  Purchaser's  determination  would  make the  consummation  of the
transactions  contemplated  by  this  Agreement  not  in  the  Purchaser's  best
interests.

                  5.7. Proceedings and Other Documents.  All corporate and other
proceedings in connection with the  transactions  contemplated by this Agreement
shall  have  been  taken  and the  Purchaser  shall  have  received  such  other
documents,  in form and substance  reasonably  satisfactory to the Purchaser and
the Purchaser's  counsel,  as to such other matters  incident to the transaction
contemplated hereby as the Purchaser may reasonably request.


                                   ARTICLE VI

                      CONDITIONS TO CLOSING OF THE COMPANY

                  The Company's obligation to sell the Securities at the Closing
is subject to the  fulfillment  to its  satisfaction  on or prior to the Closing
Date of each of the following conditions:

                  6.1.   Representations.   The  representations   made  by  the
Purchaser in Article III hereof shall be true and correct when made and shall be
true and correct on the Closing Date.


                                        8





                  6.2.  Legal  Investment.  At  the  time  of the  Closing,  the
purchase  of  the  Securities  shall  be  legally  permitted  by  all  laws  and
regulations to which the Purchaser and the Company are subject.

                  6.3.  Payment  of  Purchase  Price.  The  Company  shall  have
received payment in full of the purchase price for the Securities.


                                   ARTICLE VII

                              OPTIONAL PREPAYMENTS

                  7.1. Optional Prepayments.  The Company may, at its option, at
any time prior to maturity,  prepay the  Debenture,  in whole or in part without
premium or penalty at a price equal to the principal amount thereof plus accrued
interest thereon to the date fixed for prepayment. Any prepayments made pursuant
to this  Section  7.1 shall be applied  first to the  payment of interest on and
then to principal of the Debenture at the time outstanding.

                  7.2. Notice of Prepayment.  The right of the Company to prepay
the  Debenture  pursuant  to Section  7.1 shall be  conditioned  upon its giving
notice  of  prepayment,  signed  by its  President  and by its  Treasurer  or an
Assistant  Treasurer,  to the holder of the  Debenture not less than thirty (30)
days prior to the date upon which the prepayment is to be made (the  "Prepayment
Notice"),  specifying (a) the aggregate  principal amount of the Debenture to be
prepaid,  (b) the  date of such  prepayment,  and  (c) the  accrued  and  unpaid
interest (to and  including  the date upon which the  prepayment is to be made).
The Prepayment  Notice having been so given,  the aggregate  principal amount of
the Debenture so specified in such Prepayment Notice, and all accrued and unpaid
interest thereon, shall become due and payable on the specified prepayment date.

                  7.3.   Exercise  of  Conversion   Privilege  Upon  Receipt  of
Prepayment  Notice.  Upon  receipt  of a  Prepayment  Notice,  the holder of the
Debenture may at any time up to the third day preceding the specified prepayment
date elect to convert all or a portion of the  outstanding  principal  amount of
the Debenture in accordance with the terms of the Debenture.


                                  ARTICLE VIII

                              AFFIRMATIVE COVENANTS

                  The  Company  hereby  covenants  and  agrees,  so  long as any
Securities remain outstanding, as follows:



                                        9





                  8.1.  Maintenance  of  Corporate  Existence,   Properties  and
Leases; Taxes; Insurance.

                  (a) The Company shall and shall cause each of its subsidiaries
to,  maintain  in full  force and  effect its  corporate  existence,  rights and
franchises  and all material terms of licenses and other rights to use licenses,
trademarks,  trade names, service marks, copyrights,  patents or processes owned
or possessed by it and necessary to the conduct of its business.

                  (b) The Company shall and shall cause each of its subsidiaries
to keep each of its properties  necessary to the conduct of its business in good
repair, working order and condition, reasonable wear and tear excepted, and from
time to time  make all  needful  and  proper  repairs,  renewals,  replacements,
additions and  improvements  thereto;  and the Company shall and shall cause its
subsidiaries  to at all times comply with each material  provision of all leases
to which it is a party or under which it occupies property.

                  (c) The Company shall and shall cause each of its subsidiaries
to promptly pay and discharge,  or cause to be paid and discharged  when due and
payable,  all  lawful  taxes,  assessments  and  governmental  charges or levies
imposed upon the income,  profits,  assets,  property or business of the Company
and its  subsidiaries,  and  all  claims  or  indebtedness  (including,  without
limitation,  claims or  demands of  workmen,  materialmen,  vendors,  suppliers,
mechanics, carriers, warehousemen and landlords) which, if unpaid might become a
lien  upon the  assets or  property  of the  Company  or  subsidiary;  provided,
however,  that any such tax, assessment,  charge or levy need not be paid if the
validity  thereof  shall be  contested  timely and in good faith by  appropriate
proceedings,  if the  Company  or  subsidiary  shall have set aside on its books
adequate  reserves  with  respect  thereto,  and the failure to pay shall not be
prejudicial  in any  material  respect  to the  holders of the  Securities,  and
provided,  further,  that the Company or subsidiary will pay or cause to be paid
any such tax,  assessment,  charge or levy  forthwith upon the  commencement  of
proceedings to foreclose any lien which may have attached as security  therefor.
The Company  shall and shall cause its  subsidiaries  to pay or cause to be paid
all  other   indebtedness   incident  to  the   operations  of  the  Company  or
subsidiaries.

                  (d) The Company shall and shall cause each of its subsidiaries
to keep its assets which are of an insurable  character  insured by  financially
sound and reputable  insurers against loss or damage by theft,  fire,  explosion
and other risks customarily insured against by companies in the line of business
of the Company or its subsidiaries, in amounts sufficient to prevent the Company
or its subsidiaries from becoming a co-insurer of the property insured;  and the
Company shall and shall cause its  subsidiaries  to maintain,  with  financially
sound and  reputable  insurers,  insurance  against  other hazards and risks and
liability to persons and property to the extent and in the manner  customary for
companies in similar businesses similarly situated or as may be required by law,
including,  without  limitation,  general liability,  fire and product liability
insurance  as may be required  pursuant to any  license  agreement  to which the
Company or its subsidiaries is a party or by which it is bound.


                                       10





                  8.2. Basic  Financial  Information.  The Company shall furnish
the following reports to the Purchaser (or any transferee of any Securities), so
long as the Purchaser is a holder of any Securities:

                  (a) within  forty-five  (45) days after the end of each of the
quarterly  accounting  periods  in  each  fiscal  year,  unaudited  consolidated
statements of income and retained earnings and cash flows of the Company and its
subsidiaries  for such quarterly period and for the period from the beginning of
such fiscal year to the end of such quarterly period, together with consolidated
balance  sheets  of the  Company  and  its  subsidiaries  as at the  end of each
quarterly  period,  setting  forth in each  case  comparisons  to  corresponding
periods in the  preceding  fiscal  year,  which  statements  will be prepared in
accordance with generally accepted accounting principles, consistently applied;

                  (b) within ninety (90) days after the end of each fiscal year,
consolidated  statements  of income and retained  earnings and cash flows of the
Company and its  subsidiaries  for the period from the  beginning of each fiscal
year to the end of such fiscal year, and  consolidated  balance sheets as at the
end of such  fiscal  year,  setting  forth  in each  case  in  comparative  form
corresponding  figures for the preceding  fiscal year,  which statements will be
prepared  in  accordance   with  generally   accepted   accounting   principles,
consistently  applied  (except as approved by the accounting firm examining such
statements  and disclosed by the Company),  and will be  accompanied by a report
thereon of certified public accountants.

                  (c) promptly as legally  permitted,  any additional reports or
other detailed information  concerning significant aspects of the operations and
condition, financial or otherwise, of the Company and its subsidiaries, given to
the Company by its independent accountants;

                  (d)  within  ten  (10)  days  after  transmission  or  receipt
thereof, copies of all financial statements,  proxy statements and reports which
the  Company  sends  to  its  stockholders  or  directors,  and  copies  of  all
registration statements and all regular, special or periodic reports which it or
any of its  officers  or  directors  files  with  the  Commission  or  with  any
securities  exchange  on which any of the  securities  of the  Company  are then
listed  or  proposed  to be  listed,  copies  of all  press  releases  and other
statements  made  generally  available  by the Company to the public  concerning
material  developments in the business of the Company and its  subsidiaries  and
copies  of  material  communications  sent  to or  received  from  stockholders,
directors or  committees  of the Board of Directors of the Company or any of its
subsidiaries and copies of all material communications sent to and received from
any lender to the Company; and

                  (e) with  reasonable  promptness  such other  information  and
financial  data  concerning  the  Company  as any  person  entitled  to  receive
materials under this Section 8.2 may reasonably request.

                  8.3. Notice of Adverse Change. The Company shall promptly give
notice to all holders of any Securities (but in any event within seven (7) days)
after  becoming  aware  of  the  existence  of  any  condition  or  event  which
constitutes, or the occurrence of, any of the following:


                                       11






                  (a)      any Event of Default;

                  (b) the institution of an action,  suit or proceeding  against
the Company before any court,  administrative  agency or arbitrator,  including,
without  limitation,  any  action of a foreign  government  or  instrumentality,
which, if adversely  decided,  could  materially  adversely affect the business,
prospects,  properties,  financial  condition  or results of  operations  of the
Company, whether or not arising in the ordinary course of business; or

                  (c)  any  information  relating  to the  Company  which  could
reasonably be expected to materially and adversely affect the assets,  property,
business or condition  (financial or otherwise) of the Company or its ability to
perform the terms of this  Agreement.  Any notice  given under this  Section 8.3
shall  specify  the nature  and period of  existence  of the  condition,  event,
information,  development or  circumstance,  the anticipated  effect thereof and
what actions the Company has taken and/or proposes to take with respect thereto.

                  8.4.  Compliance  With  Agreements;  Compliance With Laws. The
Company and its subsidiaries shall comply with the material terms and conditions
of all material  agreements,  commitments or instruments to which the Company or
any of its  subsidiaries  is a party or by which  it or they may be  bound.  The
Company  shall and shall  cause each of its  subsidiaries  to duly comply in all
material respects with any material laws,  ordinances,  rules and regulations of
any foreign,  federal,  state or local government or any agency thereof,  or any
writ,  order or decree,  and conform to all valid  requirements  of governmental
authorities relating to the conduct of their respective  businesses,  properties
or assets,  including,  but not  limited  to,  the  requirements  of ERISA,  the
Environmental  Protection  Act,  the  Occupational  Safety and Health  Act,  the
Foreign  Corrupt  Practices  Act and the  rules and  regulations  of each of the
agencies administering such acts.

                  8.5. Protection of Licenses,  etc. The Company shall maintain,
defend and protect to the best of its ability  licenses and sublicenses  (and to
the  extent  the  Company  is a licensee  or  sublicensee  under any  license or
sublicense,  as permitted by the license or sublicense  agreement),  trademarks,
trade  names,  service  marks,  patents  and  applications  therefor  and  other
proprietary  information  owned or used by it and shall keep duplicate copies of
any licenses,  trademarks, service marks or patents owned or used by it, if any,
at a secure place selected by the Company.

                  8.6.     Accounts and Records; Inspections.

                  (a) The Company  shall keep true  records and books of account
in  which  full,  true  and  correct  entries  will be made of all  dealings  or
transactions  in  relation  to the  business  and affairs of the Company and its
subsidiaries in accordance with generally accepted accounting principles applied
on a consistent basis.

                  (b) The Company shall permit each holder of any  Securities or
any of such  holder's  officers,  employees or  representatives  during  regular
business  hours of the  Company,  upon  reasonable  notice  and as often as such
holder may reasonably  request,  to visit and inspect the offices and properties
of the Company and its subsidiaries and (i) to make extracts or copies


                                       12





of the books, accounts and records of the Company or its subsidiaries,  and (ii)
to  discuss  the  affairs,   finances  and  accounts  of  the  Company  and  its
subsidiaries,  with the Company's (or subsidiary's)  directors and officers, its
independent public accountants, consultants and attorneys.

                  (c) Nothing  contained  in this Section 8.6 shall be construed
to limit any rights which a holder of any  Securities (a "Holder") may have with
respect to the books and records of the Company and its subsidiaries, to inspect
its properties or to discuss its affairs, finances and accounts.

                  8.7.  NASDAQ or American Stock Exchange  Listing.  The Company
will use its best efforts to list its Common Stock on either the NASDAQ SmallCap
Market or American Stock Exchange.

                  8.8. Further  Assurances.  From time to time the Company shall
execute and deliver to the Purchaser and the Purchaser shall execute and deliver
to the Company such other  instruments,  certificates,  agreements and documents
and  take  such  other  action  and do all  other  things  as may be  reasonably
requested by the other party in order to implement or  effectuate  the terms and
provisions of this Agreement and any of the Securities.


                                   ARTICLE IX

                               EVENTS OF DEFAULTS

                  9.1. Events of Default. If any of the following events (herein
called an "Event of Default") shall occur and be continuing:

                  (a) if the  Company  shall  default in the  payment of (i) any
part of the  principal  of any  Debenture,  when the same  shall  become due and
payable,  whether  at  maturity  or  at  a  date  fixed  for  prepayment  or  by
acceleration or otherwise; or (ii) the interest on any Debenture;  when the same
shall become due and payable,  and such default in the payment of interest shall
have  continued  for ten (10)  days;  and in each case such  default  shall have
continued  without  cure for ten (10) days  after  written  notice  (a  "Default
Notice") is given to the Company of such default; or

                  (b) If the Company shall default in the  performance of any of
the covenants  contained in Article VIII and such default  shall have  continued
without  cure (i) for twenty  (20) days  after a Default  Notice is given to the
Company  with  respect to a covenant  relating to any payment of monies under an
agreement  providing  for payments of at least  $50,000 in the aggregate or (ii)
twenty (20) days after a Default  Notice is given to the Company with respect to
default in the case of a covenant  not related to the payment of monies,  by any
holder or holders of the Securities  (the Company to give forthwith to all other
holders of the Securities at the time outstanding  written notice of the receipt
of such Default Notice, specifying the default referred to therein).


                                       13





                  Notwithstanding  the  foregoing,   if  any  such  non-monetary
default shall, by its nature,  be reasonably  incapable of being cured within 20
days,  the period  within  which the  Company  shall have the right to cure such
default  shall be extended  for such  period of time as shall  enable it to cure
such default upon the exercise of due diligence.

                  (c) If the Company  shall  default in the  performance  of any
other  material  agreement  or covenant  contained  in this  Agreement  and such
default  shall not have  been  remedied  to the  satisfaction  of the  holder or
holders of at least a majority in aggregate  principal  amount of the Debentures
then outstanding, within thirty (30) days after a Default Notice shall have been
given to the Company  (the  Company to give  forthwith  to all other  holders of
Debentures and Shares at the time  outstanding  written notice of the receipt of
such Default Notice, specifying the default referred to therein); or

                  Notwithstanding  the  foregoing,   if  any  such  non-monetary
default shall, by its nature,  be reasonably  incapable of being cured within 20
days,  the period  within  which the  Company  shall have the right to cure such
default  shall be extended  for such  period of time as shall  enable it to cure
such default upon the exercise of due diligence.

                  (d) If any  representation  or warranty made in this Agreement
or in or any  certificate  delivered  pursuant  hereto  shall prove to have been
incorrect in any material respect when made; or

                  (e) If any default shall occur under any indenture,  mortgage,
agreement,  instrument or  commitment  evidencing or under which there is at the
time outstanding any indebtedness of the Company (or a Material  Subsidiary,  as
hereinafter   defined),   in  excess  of  $50,000,  or  which  results  in  such
indebtedness,  in an aggregate  amount (with other  defaulted  indebtedness)  in
excess of $50,000  becoming  due and  payable  prior to its due date and if such
indenture or instrument so requires, the holder or holders thereof (or a trustee
on their behalf) shall have declared such indebtedness due and payable; or

                  (f) If any of the Company or its subsidiaries shall default in
the  observance or  performance  of any material term or provision of a material
agreement  to which it is a party or by which it is bound,  and such  default is
not waived or cured within the applicable grace period; or

                  (g) If a final judgment  which,  either alone or together with
other  outstanding  final  judgments  against the Company and its  subsidiaries,
exceeds an  aggregate of $50,000  shall be rendered  against the Company (or any
Material  Subsidiary)  and such judgment  shall have continued  undischarged  or
unstayed for thirty (30) days after entry thereof; or

                  (h) If the Company (or any Material  Subsidiary) shall make an
assignment for the benefit of creditors, or shall admit in writing its inability
to pay its debts; or if the Company (or any Material  Subsidiary) shall suffer a
receiver or trustee for it or  substantially  all of its assets to be appointed,
and, if appointed  without its consent,  not to be  discharged  or stayed within
ninety (90) days;  or if the Company (or any Material  Subsidiary)  shall suffer
proceedings   under  any  law  relating  to   bankruptcy,   insolvency   or  the
reorganization or relief of debtors to be


                                       14





instituted  by or against it, and, if  contested  by it, not to be  dismissed or
stayed within  ninety (90) days; or if the Company (or any Material  Subsidiary)
shall suffer any writ of  attachment  or execution or any similar  process to be
issued or levied against it or any significant part of its property which is not
released,  stayed,  bonded or vacated within ninety (90) days after its issue or
levy; or if the Company (or any Material  Subsidiary)  takes corporate action in
furtherance of any of the aforesaid purposes or conditions.

                  For purposes of this Section 9.1, "Material  Subsidiary" means
any  subsidiary  with  respect to which the Company has  directly or  indirectly
invested, loaned, advanced or guaranteed the obligations of, an aggregate amount
exceeding  fifteen percent (15%) of the Company's gross assets, or the Company's
proportionate  share  of the  assets  or  net  income  of  which  (based  on the
subsidiary's most recent financial  statements)  exceed fifteen percent (15%) of
the Company's gross assets or net income, respectively, or the gross revenues of
which exceed  fifteen  percent (15%) of the gross  revenues of the Company based
upon the most recent financial statements of such subsidiary and the Company.

                  9.2.     Remedies.

                  (a) Upon the occurrence of an Event of Default,  any holder or
holders of a majority in aggregate  principal  amount of the  Debentures  at the
time  outstanding  may at any time (unless all defaults shall  theretofore  have
been  remedied)  at its or their  option,  by  written  notice or notices to the
Company (i) declare all the Debentures to be due and payable, whereupon the same
shall  forthwith  mature and  become due and  payable,  together  with  interest
accrued thereon,  without presentment,  demand,  protest or notice, all of which
are hereby waived;  and (ii) declare any other amounts  payable to the Purchaser
under this Agreement or as contemplated hereby due and payable.

                  (b)  Notwithstanding  anything contained in Section 9.2(a), in
the event that at any time after the principal of the Debentures shall so become
due and payable and prior to the date of maturity  stated in the  Debentures all
arrears of  principal of and interest on the  Debentures  (with  interest at the
rate  specified in the  Debentures on any overdue  principal  and, to the extent
legally  enforceable,  on any  interest  overdue)  shall  be  paid by or for the
account of the  Company,  then the  holder or holders of at least a majority  in
aggregate principal amount of the Debentures then outstanding, by written notice
or notices to the Company,  may (but shall not be obligated to) waive such Event
of Default and its  consequences and rescind or annul such  declaration,  but no
such waiver shall extend to or affect any subsequent  Event of Default or impair
any right  resulting  therefrom.  If any  holder of a  Debenture  shall give any
notice or take any other action with respect to a claimed default,  the Company,
forthwith  upon  receipt of such  notice or  obtaining  knowledge  of such other
action will give written  notice  thereof to all other holders of the Debentures
then  outstanding,  describing such notice or other action and the nature of the
claimed default.

                  9.3.  Enforcement.  In case any one or more  Events of Default
shall occur and be continuing,  the holder of a Debenture then  outstanding  may
proceed to protect  and  enforce  the rights of such holder by an action at law,
suit in  equity  or  other  appropriate  proceeding,  whether  for the  specific
performance of any agreement contained herein or in such Debenture


                                       15





or for an injunction  against a violation of any of the terms hereof or thereof,
or in aid of the exercise of any power granted hereby or thereby or by law. Each
holder  agrees that it will give written  notice to the other  holders  prior to
instituting  any  such  action.  In  case of a  default  in the  payment  of any
principal  of or interest on any  Debenture,  the Company will pay to the holder
thereof such  further  amount as shall be  sufficient  to cover the cost and the
expenses of collection,  including,  without limitation,  reasonable  attorney's
fees, expenses and disbursements.  No course of dealing and no delay on the part
of any holder of any  Debenture  in  exercising  any rights  shall  operate as a
waiver thereof or otherwise  prejudice such holder's rights.  No right conferred
hereby or by any  Debenture  upon any holder  thereof  shall be exclusive of any
other right referred to herein or therein or now available at law in equity,  by
statute or otherwise.


                                    ARTICLE X

                              AMENDMENT AND WAIVER

                  This  Agreement  may not be amended,  discharged or terminated
(or any provision  hereof waived) without the written consent of the Company and
the  Purchaser.  Provided  that such  written  consent  of the  Company  and the
Purchaser is given:

                  (a)  Holders of at least a  majority  in  aggregate  principal
amount of the Debentures  then  outstanding may by written  instrument  amend or
waive  any  term or  condition  of this  Agreement  relating  to the  rights  or
obligations of holders of Debentures, which amendment or waiver operates for the
benefit of such  holders,  except  that no such  amendment  or waiver  shall (i)
change the fixed  maturity of any  Debenture,  the rate or the time of mandatory
prepayment of principal  thereof or payment of interest  thereon,  the principal
amount thereof,  or the terms of  subordination,  if any, without the consent of
the holder of the Debenture so affected, (ii) change the aforesaid percentage of
Debentures,  the holders of which are required to consent to any such  amendment
or waiver,  without  the  consent  of the  holders  of all the  Debentures  then
outstanding or (iii) change the percentage of the amount of the Debentures,  the
holders of which may declare the  Debentures to be due and payable under Article
IX.

                  (b)  The  Company  and  each  holder  of a  Debenture  then or
thereafter  outstanding  shall be bound by any  amendment or waiver  effected in
accordance  with the provisions of this Article X, whether or not such Debenture
shall have been marked to indicate such  modification,  but any Debenture issued
thereafter  shall bear a notation as to any such  modification.  Promptly  after
obtaining the written consent of the holders herein provided,  the Company shall
transmit a copy of such  modification  to all of the  holders of the  Debentures
then outstanding.


                                       16





                                   ARTICLE XI

                     EXCHANGE AND REPLACEMENT OF DEBENTURES

                  11.1.  Subject to Section  12.2, at any time at the request of
any holder of one or more of the  Debentures  to the Company at its office,  the
Company at its expense (except for any transfer tax or any other tax arising out
of the  exchange)  will  issue in  exchange  therefor  new  Debentures,  in such
denomination or denominations ($100,000 or any larger multiple of $100,000, plus
one Debenture in a lesser denomination, if required) as such holder may request,
in  aggregate  principal  amount  equal to the  unpaid  principal  amount of the
Debenture or Debentures surrendered and substantially in the form thereof, dated
as of the date to which  interest has been paid on the  Debenture or  Debentures
surrendered  (or, if no interest  has yet been so paid  thereon,  then dated the
date of the Debenture or Debentures so  surrendered)  and payable to such person
or persons or order as may be designated by such holder.

                  11.2. Upon receipt of evidence  satisfactory to the Company of
the loss, theft,  destruction or mutilation of any Debenture and, in the case of
any such loss,  theft,  or  destruction,  upon  delivery of a bond of  indemnity
satisfactory  to the Company  (provided  that if the holder is a Purchaser  or a
financial institution,  its own agreement will be satisfactory),  or in the case
of any such mutilation,  upon surrender and cancellation of such Debenture,  the
Company  will  issue a new  Debenture  of like  tenor  as if the  lost,  stolen,
destroyed or mutilated  Debenture were then  surrendered for exchange in lieu of
such lost, stolen, destroyed or mutilated Debenture.


                                   ARTICLE XII

                      TRANSFER OF AND PAYMENT OF DEBENTURES

                  12.1.  Notification of Proposed Sale.

                  (a) Subject to Section 12.1(b),  each holder of a Debenture by
acceptance  thereof  agrees that it will give the Company ten (10) days  written
notice prior to selling or otherwise  disposing of such  Debenture  during which
time the  Company  may  prepay  the  Debenture  in full.  No such  sale or other
disposition  shall be made  unless (i) the holder  shall  have  supplied  to the
Company  an  opinion of counsel  for the  holder  reasonably  acceptable  to the
Company to the effect that no registration  under the Securities Act is required
with  respect  to  such  sale or  other  disposition,  or  (ii)  an  appropriate
registration statement with respect to such sale or other disposition shall have
been filed by the Company and declared effective by the Commission.

                  (b) If the holder of  Debentures  has  obtained  an opinion of
counsel reasonably  acceptable to the Company to the effect that the sale of its
Debentures may be made without registration under the Securities Act pursuant to
compliance  with Rule 144 (or any successor rule under the Securities  Act), the
holder need not provide the Company with the notice required in Section 12.1(a).



                                       17






                  (c) The Company may endorse on all  Debentures an  appropriate
legend restricting their transfer except upon compliance with this Section 12.1;
provided, however, that no such legend shall be endorsed on any Debenture which,
when issued,  is no longer subject to the restrictions of this Section 12.1, and
provided,  further,  that if an opinion of counsel  satisfactory  to the Company
concludes that the legend is no longer necessary,  the Company will deliver upon
transfer Debentures without such legends.

                  12.2. Payment. So long as the Purchaser shall be the holder of
any  Debenture,  the Company will make payments of principal and interest to the
Purchaser  no later than 11 a.m.  Eastern  Time on the date when such payment is
due.  Payments  shall be made by delivery to the  Purchaser  at the  Purchaser's
address  furnished  to the  Company  in  accordance  with  this  Agreement  of a
certified  or  official  bank  check  drawn  upon or issued by a bank which is a
member  of the New York  Clearinghouse  for  banks or by wire  transfer  to such
Purchaser's (or such Purchaser's nominee's) account at any bank or trust company
in the United States of America.  The Purchaser  further agrees that, before the
Debenture is assigned or  transferred,  the  Purchaser  will make or cause to be
made a notation thereon of principal payments previously made thereof and of the
date to which interest  thereon has been paid and will notify the Company of the
name and address of the  transferee  of such  Debenture if such name and address
are known to the Purchaser.


                                  ARTICLE XIII

                             RIGHT OF FIRST REFUSAL


                  13.1.             Right of First Refusal.

                  (a) The Company hereby agrees that if at any time prior to one
year after the  Closing  Date the Company is  considering  making an offering of
securities  in a  transaction  which  would not require  registration  under the
Securities Act by virtue of an exemption  therefrom  afforded by Regulation D or
Regulation  S  thereunder,  the  Company  shall  prepare  a term  sheet for such
offering in reasonable detail (the "Term Sheet") and transmit such Term Sheet to
the Purchaser.

                  (b) The Purchaser shall have the right to accept or reject the
terms set forth in the Term Sheet,  which such right must be exercised as to all
(but not less than all) of the  securities  being  offered  therein.  Such right
shall be exercisable by the Purchaser  within 20 days after receipt by it of the
Term  Sheet and,  if not  exercised  within  such 20 day time  period,  it shall
expire,  except as elsewhere provided in this Article XIII. If the Term Sheet is
accepted by the  Purchaser,  the Purchaser and the Company as shall be deemed to
have agreed to use their bona fide best efforts to consummate the transaction on
the terms set forth in the Term Sheet as promptly as possible. If the Term Sheet
is rejected  by the  Purchaser,  or if the  Purchaser  does not serve  notice of
acceptance of the Term Sheet within the aforesaid  20-day  period,  the Company,
without further obligation of any kind, including any requirement to give notice
to  the  Purchaser,  may  make  one  or  more  offerings  to  third  parties  on
substantially the same terms


                                       18





as those  set  forth  in the  Term  Sheet  or on  different  terms  which in the
reasonable  opinion of the Company are in the  aggregate  more  favorable to the
Company  than  the  terms  set  forth in the Term  Sheet,  and if such  offer is
accepted by any such third party,  the Company shall be free to consummate  such
offering in accordance with its terms.

                  (c) If the Company  shall have  followed  the  procedures  set
forth in subparagraphs  (a) and (b) hereof,  but no transaction  shall have been
consummated  within 120 days with the  Purchaser or any third party  pursuant to
the terms of the Term Sheet which shall have been  distributed,  such Term Sheet
shall be withdrawn by the Company from  circulation  and the  provisions of this
Article XIII shall be applicable ab initio to any new Term Sheet.

                  (d) If the Company  shall  receive an offer from a third party
prospective investor with respect to the Term Sheet referred to in subparagraphs
(a) and (b) hereof,  which is modified in any material  business  respect to the
benefit of such  investor and the  detriment of the Company,  such modified Term
Sheet  shall  not be  accepted  by the  Company  until it shall  have  given the
Purchaser  the right to accept the terms as so  modified,  which  right shall be
exercisable  by the  Purchaser  for 15 days after  receipt of the modified  Term
Sheet.  Failure to accept the  modified  Term Sheet  within the  aforesaid  time
period shall conclusively be deemed to be a rejection thereof.

                  (e) If the Company  shall  comply with the  provision  of this
Article XIII,  and  consummate  Regulation D or Regulation S transaction  with a
third party  investor upon the terms and  conditions  contemplated  hereby,  the
right of First  Refusal  granted to the  Purchaser  in this  Article  XIII shall
terminate  and  be  of  no  further  force  and  effect   immediately  upon  the
consummation of such transaction.


                                   ARTICLE XIV

                                  MISCELLANEOUS

                  14.1.  Governing  Law.  This  Agreement  and the rights of the
parties  hereunder shall be governed in all respects by the laws of the State of
New York.

                  14.2. Survival. The representations, warranties, covenants and
agreements made herein shall survive (a) any investigation made by the Purchaser
and (b) the Closing.

                  14.3.  Successors and Assigns.  Except as otherwise  expressly
provided  herein,  the  provisions  hereof shall inure to the benefit of, and be
binding upon and  enforceable by and against,  the successors,  assigns,  heirs,
executors and administrators of the parties hereto; provided,  however, that the
Company may not assign its rights hereunder.

                  14.4. Entire Agreement. This Agreement (including the Exhibits
hereto) and the other documents  delivered  pursuant  hereto and  simultaneously
herewith constitute the full and entire  understanding and agreement between the
parties with regard to the subject matter hereof and thereof.


                                       19





                  14.5.   Notices,   etc.   All   notices,   demands   or  other
communications  given  hereunder  shall be in writing and shall be  sufficiently
given if  delivered  either  personally  or by a nationally  recognized  courier
service  marked for next  business day delivery or sent in a sealed  envelope by
first class mail, postage prepaid and either registered or certified,  addressed
as follows:

                  (a) if to the Company:

                          Advanced Viral Research Corp.
                          200 Corporate Boulevard South
                          Yonkers, New York 10701
                          Attention:  Shalom Z. Hirschman, M.D., President and
                                      Chief Executive Officer

                  (b) if to the Purchaser, to the address set forth on the first
                      page of this Agreement.

or to such other address with respect to any party hereto as such party may from
time to time  notify (as  provided  above) the other  parties  hereto.  Any such
notice,  demand or  communication  shall be deemed to have been given (i) on the
date of delivery, if delivered personally,  (ii) one business day after delivery
to a nationally  recognized  overnight  courier service,  if marked for next day
delivery or (iii) five business days after the date of mailing, if mailed.

                  Copies of any  notice,  demand or  communication  given to the
Company,  shall be delivered to Lowenthal,  Landau,  Fischer & Bring,  P.C., 250
Park Avenue, New York, New York, 10177, Attn.: Robert E. Fischer,  Esq., or such
other address as may be directed.

                  14.6.  Delays or  Omissions.  No delay or omission to exercise
any right,  power or remedy  accruing to any holder of any  Securities  upon any
breach or default of the  Company  under this  Agreement  shall  impair any such
right,  power or remedy of such holder nor shall it be  construed to be a waiver
of any such  breach  or  default,  or an  acquiescence,therein,  or of or in any
similar  breach or  default  thereafter  occurring;  nor shall any waiver of any
single  breach or  default  be deemed a waiver  of any other  breach or  default
theretofore or thereafter occurring.  Any waiver, permit, consent or approval of
any kind or character  on the part of any holder of any breach or default  under
this  Agreement,  or any waiver on the part of any holder of any  provisions  or
conditions  of this  Agreement  must be, made in writing and shall be  effective
only to the extent specifically set forth in such writing. All remedies,  either
under this  Agreement  or by law or otherwise  afforded to any holder,  shall be
cumulative and not alternative.

                  14.7.  Rights;   Severability.   Unless  otherwise   expressly
provided  herein,  each  Purchaser's  rights  hereunder are several rights,  not
rights  jointly  held  with any  other  person.  In case any  provision  of this
Agreement shall be invalid, illegal or unenforceable, the validity, legality and
enforceability  of the remaining  provisions shall not in any way be affected or
impaired thereby.


                                       20





                  14.8. Agent's Fees.

                  (a) The Company hereby (i) represents and warrants that except
for Interfi Group,  Inc.  ("Interfi"),  the Company has not retained a finder or
broker in connection  with the  transactions  contemplated by this Agreement and
(ii)  agrees to  indemnify  and to hold the  Purchaser  harmless of and from any
liability for commission or  compensation in the nature of an agent's fee to any
broker,  person or firm  (including  Interfi),  and the costs  and  expenses  of
defending  against such  liability  or asserted  liability,  including,  without
limitation,  reasonable  attorney's fees, arising from any act by the Company or
any of the Company's employees or representatives;  provided,  however, that the
Company   will  have  the   right  to   defend   against   such   liability   by
representative(s) of its own choosing,  and provided,  further, that the Company
will not settle or compromise any claim or lawsuit  without prior written notice
to the  Purchaser  of the terms and  provisions  thereof.  In the event that the
Company shall fail to undertake  the defense  within ten (10) days of any notice
of such claim,  the  Purchaser  shall have the right to  undertake  the defense,
compromise  or  settlement  of such claim upon written  notice to the Company by
holders of a majority in principal amount of the Debentures and the Company will
be  responsible  for and  shall pay all costs and  expenses  of  defending  such
liability or asserted liability and any amounts paid in settlement.

                  (b) The  Purchaser  (i)  represents  and warrants  that it has
retained no finder or broker in connection with the transactions contemplated by
this  Agreement  and (ii) hereby  severally  agrees to indemnify and to hold the
Company  harmless from any liability for any commission or  compensation  in the
nature of an agent's or finder's  fee to any broker or other person or firm (and
the costs,  including  reasonable legal fees, and expenses of defending  against
such liability or asserted  liability) for which such  Purchaser,  or any of its
employees or representatives, are responsible.

                  14.9.  Expenses.  Each  of the  parties  shall  bear  its  own
expenses and legal fees incurred on its behalf with respect to the  negotiation,
execution and consummation of the transactions contemplated by this Agreement.

                  14.10. Litigation. The parties each hereby waive trial by jury
in any  action  or  proceeding  of any kind or  nature  in any court in which an
action may be commenced  arising out of this Agreement or by reason of any other
cause or dispute  whatsoever  between  them.  The parties  hereto agree that the
State and  Federal  Courts  which sit in the State of New York and the County of
New York shall have exclusive  jurisdiction  to hear and determine any claims or
disputes between the Company and such holders, pertaining directly or indirectly
to this Agreement or to any matter arising therefrom. The parties each expressly
submit and consent in advance to such  jurisdiction  in any action or proceeding
commenced in such courts  provided that such consent shall not be deemed to be a
waiver of personal  service of the summons and  complaint,  or other  process or
papers issued therein. The choice of forum set forth in this Section 14.10 shall
not be deemed to preclude the enforcement of any judgment obtained in such forum
or the  taking  of any  action  under  this  Agreement  to  enforce  same in any
appropriate jurisdiction.  The parties each waive any objection based upon forum
non conveniens and any objection to venue of any action instituted hereunder.


                                       21





                  14.11.  Titles  and  Subtitles.  The  titles of the  articles,
sections and subsections of this Agreement are for convenience of reference only
and are not to be considered in construing this Agreement.

                  14.12.  Counterparts.  This  Agreement  may be executed in any
number of  counterparts,  each of which shall be an  original,  but all of which
together shall constitute one instrument.

                  If the  Purchaser  is in  agreement  with  the  foregoing  the
Purchaser  shall sign where  indicated  below and  thereupon  this letter  shall
become a binding agreement between the Purchaser and the Company.

                           Very truly yours,

                           ADVANCED VIRAL RESEARCH CORP.


                           By:
                                Shalom Z. Hirschman, M.D., President and
                                Chief Executive Officer


AGREED:

RBB BANK AKTIENGESELLSCHAFT


By:

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