ARTICLES OF AMENDMENT
                                     TO THE
                            ARTICLES OF INCORPORATION
                                       OF
                                 ENTROPIN, INC.

     Pursuant to Section  7-106-102 of the Colorado  Business  Corporation  Act,
Entropin, Inc. (the "Corporation") adopts the following Articles of Amendment to
its Articles of Incorporation, as amended and restated:

     1. The name of the corporation is Entropin, Inc.

     2. The  Articles  of  Incorporation,  as amended and  restated,  hereby are
amended to include Exhibit A attached  hereto,  which designates a series of the
Corporation's  preferred stock (the "Series B Nonvoting  Convertible  Redeemable
Preferred  Stock")  and sets forth the  preferences,  limitations  and  relative
rights of such preferred stock.

     3.  This  Amendment  was duly  adopted  by the  Board of  Directors  of the
Corporation on June 23, 1998.

     On behalf of Entropin,  Inc.,  Higgins D. Bailey,  Chairman of the Board of
Directors,  by his signature below, does hereby confirm,  under the penalties of
perjury,   that  the  foregoing   Articles  of  Amendment  to  the  Articles  of
Incorporation, as amended and restated, of Entropin, Inc. are a true and correct
copy of said document.

                                        ENTROPIN, INC.


                                        By  \s\ Higgins D. Bailey
                                            -----------------------------------
                                            Higgins D. Bailey, Chairman of the
                                            Board of Directors

                                    EXHIBIT A

     RESOLVED,  that a series  of the  class of  authorized  Preferred  Stock be
hereby  created,  and the  designation and amount thereof and the voting powers,
preferences  and relative,  participating,  optional and other special rights of
the shares of such series, and the  qualifications,  limitations or restrictions
thereof are as follows:

          SECTION 1. DESIGNATION AND AMOUNT.  The shares of such series shall be
designated  as shares of "Series B Nonvoting  Convertible  Redeemable  Preferred
Stock" (the  "Series B Preferred  Stock") and the number of shares  constituting
such series shall be four hundred thousand (400,000).

          SECTION 2. DIVIDEND RIGHTS.  Dividends on the Series B Preferred Stock
shall accrue at the rate of $.50 per annum, shall be cumulative from the date of
first issuance and shall be paid annually in arrears  commencing  July 15, 1998.
At the  Corporation's  election,  annual dividends may be paid in cash and/or in
shares of the Corporation's Common Stock, $.001 par value per share (the "Common
Stock"),  at the rate of one share of Common  Stock  for each  $5.00 in  accrued
dividends.

          SECTION  3.  CONVERSION  RIGHTS.  The  Series  B  Preferred  Stock  is
convertible at the option of the holder at any time into shares of the Company's
Common Stock. The number of shares of Common Stock issuable upon conversion of a
share of Series B Preferred  Stock is equal to:  $5.00,  plus accrued and unpaid
dividends,  divided by $5.00 (the "Conversion Price"),  subject to adjustment to
reflect any stock split, stock dividend,  combination,  recapitalization and the
like. Assuming no accrued and unpaid dividends, each share of Series B Preferred
Stock will be convertible to one share of Common Stock.

          SECTION 4. MANDATORY  REDEMPTION  RIGHTS. The Series B Preferred Stock
shall be issued and  outstanding  for a period not to exceed five (5) years from
the  date of  issuance  ("Expiration  Date"),  at  which  time  all  issued  and
outstanding  shares of Series B Preferred  Stock  shall be subject to  mandatory
redemption  by the  Corporation  at the  redemption  price of $5.00  per  share,
together with all accrued and unpaid dividends up to the Expiration Date.

          SECTION 5. ELECTIVE  REDEMPTION.  Prior to the  Expiration  Date,  the
Corporation may, at its sole and exclusive option,  redeem or otherwise acquire,
in whole or in part on a pro rata  basis  with  other  holders  of the  Series B
Preferred  Stock,  outstanding  Series B Preferred  Stock upon 30 days'  written
notice  (the  "Notice of  Redemption")  to the holders of the Series B Preferred
Stock at $5.00 per share plus  accrued and unpaid  dividends  to the  redemption
date.  Notwithstanding  the foregoing,  in the event the Corporation redeems the
Series B  Preferred  Stock  within  one year  from  the  date of  issuance,  the
redemption price shall be $6.00 per share;  provided,  however, in the event the
Corporation redeems the Series B Preferred Stock within six months from the date
of  issuance,  the  holders  of the Series B  Preferred  Stock  shall  receive a
dividend equal to one-half of the annual accrued dividend  amount.  The Series B
Preferred  Stock may be converted by the holders  during the 30 day period prior
to the effective date of redemption  set forth in the Notice of Redemption  (the



"Effective  Date").  If not  converted,  the Series B  Preferred  Stock,  or any
portion thereof  identified in the Corporation's  Notice of Redemption,  will be
redeemed on the Effective  Date. In the event fewer than the total number of the
Corporation's  Series B Preferred  Stock are redeemed,  the Company will issue a
new stock  certificate  representing the number of unredeemed shares of Series B
Preferred Stock to the holder without cost to such holder.

          SECTION  6.  NOTICE  OF  REDEMPTION.  The  Corporation  will  send  by
registered mail written notice of each redemption of Series B Preferred Stock to
each record  holder of Series B Preferred  Stock not more than 30 days after the
date  the  Board  of  Directors   approved  the   redemption   (the  "Notice  of
Redemption").  Upon  mailing any Notice of  Redemption,  the  Corporation  shall
become  obligated  to redeem the  specified  total  number of Series B Preferred
Stock at the specified time of redemption, which time shall in no event be later
than 90 days after the Board of Directors approved the redemption.

          SECTION 7. EFFECT OF  REDEMPTION  OR  PURCHASE.  Any share of Series B
Preferred Stock that is redeemed or otherwise  acquired by the Corporation shall
be deemed canceled immediately upon redemption or acquisition by the Corporation
without  any  further  act  or  notice  and  shall  not  be  reissued,  sold  or
transferred.  In case fewer than the total  number of Series B  Preferred  Stock
shares represented by any certificate are redeemed, the Corporation will issue a
new certificate  representing the number of unredeemed  Series B Preferred Stock
shares to the holder thereof without cost to such holder.

          SECTION 8.  CANCELLATION.  If any shares of Series B  Preferred  Stock
remains  outstanding as of 11:59 p.m., Mountain Daylight Time, on the Expiration
Date, such share shall be deemed canceled  immediately without any act or notice
by the Corporation and all rights attendant to such share shall cease.

          SECTION  9.  LIQUIDATION  RIGHTS.  In the  event of any  voluntary  or
involuntary  liquidation,  dissolution  or  winding-up  of  the  affairs  of the
Corporation  during the five year period from the date of issuance of the Series
B Preferred Stock, after payment or provision for payment of the debts and other
liabilities of the Corporation,  and subordinate to the rights of the holders of
the outstanding shares of the Corporation's  Series A Preferred Stock to receive
$1.00 per share in liquidation, the holders of Series B Preferred Stock shall be
entitled to receive,  prior and in preference to any  distribution of any of the
assets or surplus funds of the  Corporation to the holders of the  Corporation's
other preferred stock or the Common Stock of the Corporation, by reason of their
ownership  thereof,  an amount equal to five dollars  ($5.00) for each share, as
appropriately adjusted to reflect any stock split, stock dividend,  combination,
recapitalization and the like.

          All  preferential  amounts  to be paid to the  holders of the Series B
Preferred  Stock  under  this  Section 8 shall be paid or set apart for  payment
after the  payment  or  setting  apart for  payment  of any  amount  for (or the
distribution   of  any  assets  of  the  Corporation  to)  the  holders  of  the

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Corporation's  Series A Preferred Stock, and before the payment or setting apart
for  payment  of any  amount  for  (or the  distribution  of any  assets  of the
Corporation  to) the holders of the  Corporation's  other preferred stock or the
Common Stock of the Corporation in connection with such liquidation, dissolution
or winding-up, and the holders of such other preferred stock or the Common Stock
of the Corporation  shall share ratably all remaining  assets of the Corporation
with no  further  right of  participation  accruing  to any  holder  of Series B
Preferred Stock. If the assets or surplus funds to be distributed to the holders
of the Series B Preferred  Stock are  insufficient to permit the payment to such
holders  of their  full  preferential  amount  in the  event  of a  liquidation,
dissolution  or winding up of the  affairs  of the  Corporation,  the assets and
surplus funds legally  available for distribution  shall be distributed  ratably
first to the holders of the Corporation's  outstanding  Series A Preferred Stock
and next among the holders of the Series B Preferred  Stock in proportion to the
full  preferential  amount  each such  holder  would  otherwise  be  entitled to
receive.

          SECTION 10. VOTING RIGHTS.

          (a) NO VOTING  RIGHTS.  The  holders  of shares of Series B  Preferred
Stock shall not be entitled to vote upon matters submitted to shareholders for a
vote.

          (b) NOTICE. The holders of Series B Preferred Stock shall not
be entitled to receive notice of meetings of the shareholders.

          SECTION 11.  AMENDMENTS.  No amendment  shall be made to the rights or
obligations of the Series B Preferred Stock.

          SECTION 12. OTHER CLASSES OR SERIES.  Nothing  contained  herein shall
preclude the Corporation from issuing, at any time and from time to time, shares
of one or more  other  classes or series of  preferred  stock  authorized  to be
issued by the Articles of the Corporation (as may be amended from time to time),
which shall be subordinate  first to the Series A Preferred  Stock and second to
the Series B Preferred Stock in redemption and liquidation rights.

          SECTION 13.  RESIDUAL  RIGHTS.  All rights accruing to the outstanding
shares of the Corporation  not expressly  provided for to the contrary herein or
reserved to other  series of  preferred  stock,  if any,  shall be vested in the
Common Stock of the Corporation.

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