UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549




                                    FORM 8-K

                                 CURRENT REPORT
     PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934




Date of Report (Date of earliest event reported):  March 31, 2004




                         ARROWHEAD RESEARCH CORPORATION
                         ------------------------------
             (Exact name of registrant as specified in its charter)


           Delaware                 000-21898                46-0408024
           --------                 ---------                ----------
(State or other jurisdiction      (Commission             (I.R.S. Employer
      of  incorporation)          File  Number)         Identification  No.)


            150 S. Los Robles, Ste. 480, Pasadena, CA          91101
           --------------------------------------------        -----
           (Address  of  principal  executive  offices)      (Zip Code)


Registrant's telephone number, including area code:  (626) 792-5549


                                 Not Applicable
                                 --------------
          (Former name or former address, if changed since last report)


ITEM  5.  OTHER  EVENTS  AND  REGULATION  FD  DISCLOSURE.

Changes in the Composition of the Board of Directors
- ----------------------------------------------------

     Arrowhead  Research  Corporation  (the  "Company")  has  previously filed a
Registration  Statement on Form S-3 with the Securities and Exchange Commission,
for  the  purpose of registering for resale under the Securities Act of 1933, as
amended  (the  "Securities Act")  all of the outstanding shares of the Company's
common  stock  and  common  stock  purchase  warrants  that  were issued without
registration  under  the Securities Act in connection with the transactions that
resulted  in  the  January 12, 2004 change in control of the Company's ownership
and  plan  of  operations.  The  Registration  Statement on Form S-3 has not yet
become effective, and none of the securities may publicly be sold nor may offers
to  buy  be  accepted  prior  to  the  time  the  Registration Statement becomes
effective. This Current Report on Form 8-K shall not constitute an offer to sell
or  the  solicitation  of  an  offer  to  buy nor shall there be any sale of the
securities  covered  by  the  Registration Statement on Form S-3 in any State in
which  such  offer, solicitation or sale would be unlawful prior to registration
or  qualification  under  the  securities  laws  of  any  such  State.

     An  application  is  being  submitted  to  The  NASDAQ Stock Market for the
approval  of  the  Company's  common  stock  and  stock  purchase  warrants  for
quotation  on  The  NASDAQ  SmallCap  Market as of such time as the Registration
Statement  becomes effective under the Securities Act. Among other conditions to
a  listing  on  The  NASDAQ  SmallCap  Market,  the Company must have a majority
of  "independent  directors,"  as  defined  in  the  NASDAQ  Marketplace  Rules.
Accordingly,  on  March  31,  2004,  Drs.  Charles  Patrick  Collier and Marc W.
Bockrath  resigned  from  the  Company's  Board of Directors, in order to create
vacancies  on  the  Board  of  Directors that could be filled by individuals who
would meet the "independent director" requirement for a NASDAQ listing. Prior to
their  resignations  from  the  Board  of Directors, there were no disagreements
between  the  Company  and  either  of  Drs.  Collier and Bockrath on any matter
relating  to  the  Company's  operations,  policies  or  practices.

     On April 5, 2004, Charles P. McKenney was elected by the Company's Board of
Directors  to  fill  one  of  the  two  vacancies  on  the  Board created by the
resignations  of  Drs.  Collier  and Bockrath.  As a result of his election as a
director,  the  Company's  Board  of  Directors  currently  is comprised of five
individuals,  three of whom, Edward W. Frykman, LeRoy Rahn and Mr. McKenney, are
"independent"  for  purposes  of  the  proposed  listing  on The NASDAQ SmallCap
Market.

     Mr.  McKenney,  age 65, has maintained a government affairs law practice in
Pasadena,  California  since  1989, representing businesses and organizations in
their  relations  with  government  regarding  their obligations under state and
local  land  use and trade practices laws.  From 1973 through 1989, he served as
Attorney  for  Corporate  Government Affairs for Sears, Roebuck and Co., helping
organize  and  carry  out  Sears'  Western  state and local government relations
programs.  Mr.  McKenney  has  served two terms on the Pasadena, California City
council, on several city boards and committees in Pasadena, including three city
Charter  Reform  Task  Forces,  and  as  Pasadena's first appointee to the Santa
Monica  Mountains Conservancy Advisory Committee.  He has been granted an option
to  purchase, at the price of $1.00, up to 25,000 shares of the Company's common
stock under  the  Company's  2000  Stock  Option  Plan.


                                      - 2 -

Establishment  of  an  Audit  Committee.
- ---------------------------------------

     With  the  addition  of  Mr.  McKenney  to the Board of Directors, an Audit
Committee of the Board of Directors has been established, comprised of the three
independent  directors,  Messrs. Frykman, Rahn and McKenney. The Audit Committee
is  responsible  for  retaining, evaluating  and, if  appropriate,  recommending
the termination of  the  Company's  independent  accountants  and  is  primarily
responsible  for  approving  the services performed by the Company's independent
accountants   and  for  reviewing   and  evaluating   the  Company's  accounting
principles, financial reporting practices, and its system of internal accounting
controls.  The Audit Committee is also responsible for maintaining communication
between  the  Board  of Directors and the Company's independent accountants. The
Board  of  Directors  has  determined  that  Mr.  Frykman is an "audit committee
financial  expert"  as  defined  in  Item  401(e)  of  Regulation  S-B under the
Securities  Exchange  Act  of  1934.

Adoption of Code of Corporate Conduct
- -------------------------------------

     The  Company's  Board  of  Directors  also  has adopted a Code of Corporate
Conduct  that  applies  to  all  of the Company's employees, including its chief
executive  officer,  chief  financial  and accounting officer, president and any
persons performing similar functions. A copy of the Code of Corporate Conduct is
filed  herewith  as  an  Exhibit to this Current Report on Form 8-K, and shortly
will  be  available on the Company's internet website at www.arrowres.com, or by
                                                         ----------------
written  request  addressed  to  the  Company at 150 S. Los Robles Avenue, Suite
480,  Pasadena,  California  91101.

Formation  of a Scientific  Advisory  Board
- -------------------------------------------

     Concurrent  with  their resignations from the Company's Board of Directors,
Drs.  Bockrath  and  Collier  were  elected  to  serve  on  the  Company's newly
established  Scientific  Advisory  Board.  The Scientific Advisory Board will be
comprised  of  individuals  who  can  provide  consultation  to  the  Company's
Management  on  scientific  matters.


ITEM  7.  FINANCIAL  STATEMENTS  AND  EXHIBITS.

     (c)  Exhibits.  The  following  document  is  filed  as  an exhibit to this
Current  Report  on  Form  8-K:

          Exhibit  No.             Description             Page Number
          ------------             -----------             -----------

              14           Code of Corporate Conduct            5


ITEM  10.  AMENDMENTS  TO  THE  REGISTRANT'S  CODE  OF  ETHICS,  OR  WAIVER OF A
PROVISION  OF  THE  CODE  OF  ETHICS.

     Please  see  Item  5  above.


                                      - 3 -

                                   SIGNATURES

     Pursuant  to  the  requirements of the Securities Exchange Act of 1934, the
registrant  has  duly  caused  this  report  to  be  signed on its behalf by the
undersigned  hereunto  duly  authorized.

Date:     April  5,  2004
                                     ARROWHEAD  RESEARCH  CORPORATION


                                     By:  /s/ R. Bruce Stewart
                                          ----------------------------------
                                          R. Bruce Stewart, President


                                      - 4 -