Exhibit 2.1


                      AGREEMENT AND PLAN OF REORGANIZATION


                                  BY AND AMONG


                             PHARMAFRONTIERS CORP.,


                            PHARMA ACQUISITION CORP.,

                                       AND

                          OPEXA PHARMACEUTICALS, INC.,

                           DATED AS OF OCTOBER 7, 2004



                      AGREEMENT AND PLAN OF REORGANIZATION

     This  AGREEMENT  AND  PLAN OF REORGANIZATION is made and entered into as of
October  7,  2004,  among PharmaFrontiers Corp., a Texas corporation ("PARENT"),
Pharma  Acquisition  Corp., a Delaware corporation and a wholly-owned subsidiary
of  Parent  ("MERGER  SUB")   and  Opexa  Pharmaceuticals,  Inc.,  a  Delaware
corporation  ("COMPANY").


                                    RECITALS
                                    --------

     A.   Upon  the  terms  and  subject to the conditions of this Agreement (as
defined  in  Section  1.2  below)  and  in  accordance with the Delaware General
Corporation Law ("DELAWARE LAW"), Parent, Merger Sub and Company intend to enter
into  a  business  combination  transaction.

     B.   The  Board  of Directors of Company (i) has determined that the Merger
(as  defined  in  Section  1.1)  is  consistent  with  and in furtherance of the
long-term  business  strategy  of Company and fair to, and in the best interests
of,  Company  and its shareholders, (ii) has approved this Agreement, the Merger
and  the  other  transactions  contemplated  by  this  Agreement,  and (iii) has
determined  to recommend that the shareholders of Company adopt and approve this
Agreement  and  approve  the  Merger.

     C.   The Board of Directors of Parent (i) has determined that the Merger is
consistent  with and in furtherance of the long-term business strategy of Parent
and  is  fair to, and in the best interests of, Parent and its stockholders, and
(ii)  has  approved  this  Agreement,  the  Merger  and  the  other transactions
contemplated  by  this  Agreement.  The Board of Directors of and shareholder of
Merger  Sub  (i)  have  determined  that  the Merger is fair to, and in the best
interests of, Parent and its shareholder, and (ii) have approved this Agreement,
the  Merger  and  the  other  transactions  contemplated  by  this  Agreement.

     D.   Concurrently  with  the execution of this Agreement as a condition and
inducement  to  Parent's  willingness  to  enter  into  this  Agreement, certain
shareholders  of the Company, including Top Tier Investments, LLC, Jingwu Zhang,
M.D.,  Davis Investments V, L.P., Michael Redman, Terry and Mary Ann Wesner (for
their  own  behalf and on behalf of any retirement accounts which own shares for
their  benefit),  Odyssey  Strategic  Equity,  LLC  are  entering  into  Voting
Agreements  in  the  form  attached  hereto  as  Exhibit  A (the "COMPANY VOTING
AGREEMENTS").

     E.   Concurrently  with  the execution of this Agreement as a condition and
inducement  to  Parent's  willingness  to enter into this Agreement, the Company
will  enter  into  a  Termination  Agreement with Michael Redman terminating his
Employment  Agreement, dated September 5, 2001, such Termination Agreement shall
be  in  the  form attached hereto as Exhibit B ("REDMAN TERMINATION AGREEMENT").

     F.   The  parties  intend,  by executing this Agreement, to adopt a plan of
reorganization within the meaning of Section 368(a) of the Internal Revenue Code
of  1986,  as  amended  (the  "CODE").

     NOW,  THEREFORE,  in  consideration  of  the  covenants,  promises  and
representations  set forth herein and for other good and valuable consideration,
the  receipt and sufficiency of which are hereby acknowledged, the parties agree
as  follows:


                                        2

                                   ARTICLE I.

                                   THE MERGER

     1.1  THE MERGER.

     At  the  Effective Time (as defined in Section 1.2) and subject to and upon
the  terms  and  conditions  of  this Agreement and the applicable provisions of
Delaware  Law,  Merger Sub shall be merged with and into Company (the "MERGER"),
the  separate  corporate  existence  of Merger Sub shall cease and Company shall
continue  as  the  surviving  corporation  and  as  a wholly-owned subsidiary of
Parent.  Company  as  the  surviving corporation after the Merger is hereinafter
sometimes  referred  to  as  the  "SURVIVING  CORPORATION."

     1.2  EFFECTIVE TIME; CLOSING.

     Subject to the provisions of this Agreement, the parties hereto shall cause
the  Merger  to  be  consummated  by  filing an agreement and plan of merger and
articles,  certificates or other appropriate filing documents with the Secretary
of  State of the State of Delaware in accordance with the relevant provisions of
Delaware  Law (collectively, the "CERTIFICATE OF MERGER") as soon as practicable
on  or after the Closing Date (as herein defined). The "EFFECTIVE TIME" shall be
the time no later than October 31, 2004, unless Parent has elected to extend the
Effective  Time  pursuant  to Section 6.3 of this Agreement.  Unless the context
otherwise  requires,  the term "AGREEMENT" as used herein refers collectively to
this  Agreement  and  Plan of Reorganization and the Certificate of Merger.  The
closing  of the Merger (the "CLOSING") shall take place at the offices of Brewer
& Pritchard, P.C., Three Riverway, 18th Floor, Houston, Texas at a time and date
to be specified by the parties, which shall be no later than the second business
day  after the satisfaction or waiver of the conditions set forth in Article VI,
or  at such other time, date and location as the parties hereto agree in writing
(the  "CLOSING  DATE"). The Effective Time and the Closing Date shall be one and
the  same.

     1.3  EFFECT OF THE MERGER.

     At  the  Effective  Time,  the effect of the Merger shall be as provided in
this  Agreement and the applicable provisions of Delaware Law.  Without limiting
the  generality of the foregoing and subject thereto, at the Effective Time, all
the  property,  rights, privileges, powers, and franchises of Company and Merger
Sub  shall  vest  in  the  Surviving Corporation and all debts, liabilities, and
duties of Company and Merger Sub shall become the debts, liabilities, and duties
of  the  Surviving  Corporation.

     1.4  CERTIFICATE OF INCORPORATION; BYLAWS.

     (a)  At the Effective Time, the Certificate of Incorporation of Company, as
in  effect  immediately prior to the Effective Time, shall be the Certificate of
Incorporation  of the Surviving Corporation until thereafter amended as provided
by  law  and  such  Certificate  of  Incorporation of the Surviving Corporation.

     (b)  The Bylaws of Company, as in effect immediately prior to the Effective
Time,  shall  be, at the Effective Time, the Bylaws of the Surviving Corporation
until  thereafter  amended.

     1.5  DIRECTORS AND OFFICERS.

     At  the Effective Time, the directors of the Surviving Corporation shall be
the directors of Parent plus up to two (2) directors selected by the Company and
in  accordance  with the License Agreement (as defined in Section 2.9), at least
one (1) of whom shall be "independent" as defined in the Securities Act of 1933,
as  amended,  each  to  hold  office  in  accordance  with  the  Certificate  of
Incorporation  and  Bylaws  of  the Surviving Corporation until their respective
successors  are duly elected or appointed and qualified.  At the Effective Time,
the officers of the Surviving Corporation shall be the officers of Company, each
to hold office in accordance with the Certificate of Incorporation and Bylaws of
the  Surviving Corporation until their respective successors are duly appointed.


                                        3

     1.6  EFFECT ON CAPITAL STOCK.

     Subject  to  the  terms  and conditions of this Agreement, at the Effective
Time,  by virtue of the Merger and without any action on the part of Merger Sub,
Company  or  the holders of any of the following securities, the following shall
occur:

     (a)  Conversion  of  Company  Preferred  Stock  and  Company  Common Stock.
          ----------------------------------------------------------------------

          (i)  Parent  shall  issue  to  the holders of Company Common Stock and
Company  Preferred  Stock  (each  of  which  is  defined  below) an aggregate of
2,500,000  shares of its common stock, par value $.001 per share ("PARENT COMMON
STOCK"),  at  the  Effective  Time  as consideration for the Merger (assuming no
dissenter's  rights  have  been perfected), together with those shares of Parent
Common  Stock  provided  for in Section 1.6(e), if applicable.  At the Effective
Time,  each  issued  and  outstanding  share of the Company's Series A Preferred
Stock,  par  value  $0.001  per  share  ("COMPANY  PREFERRED STOCK"), other than
dissenting  shares  of  Company  Preferred  Stock,  shall  be  cancelled  and
extinguished  and  automatically  converted (subject to Sections 1.6(e) and (f))
into the right to receive shares of Parent Common Stock, as set forth on Exhibit
C,  upon  surrender  of the certificate representing shares of Company Preferred
Stock  in  the  manner provided in Section 1.7 or Section 1.9.  At the Effective
Time,  each  share  of  the Company's outstanding common stock, ("COMPANY COMMON
STOCK"),  including  the exercise of the  Company Options (as defined in Section
2.2)  and  excluding  any dissenting shares of Company Common Stock or shares of
Company  Common  Stock  to  be  cancelled  pursuant  to Section 1.6(b)), will be
cancelled  and  extinguished  and  automatically  converted (subject to Sections
1.6(e)  and (f)) into the right to receive shares of Parent Common Stock, as set
forth on Exhibit C, upon surrender of the certificate representing such share of
Company Common Stock in the manner provided in Section 1.7 or Section 1.9. Prior
to  the  Effective  Time,  each  Company  Option shall be either accelerated and
exercised or terminated.  Each Company Warrant (as defined in Section 2.2) shall
be terminated prior to the effective time, and therefore, the holders of Company
Warrants shall not be entitled to the right to receive or purchase any shares of
Parent  Company  Stock.

          (ii) If  any  shares  of  Company Common Stock outstanding immediately
prior  to the Effective Time are unvested or are subject to a repurchase option,
risk  of  forfeiture,  or  other condition under any applicable restricted stock
purchase  agreement  or  other  agreement with the Company, then, subject to the
terms  of  the  plan or agreement pursuant to which such shares were issued, the
shares  of  Parent  Common  Stock  issued in exchange for such shares of Company
Common  Stock  will  also be unvested and subject to the same repurchase option,
risk  of  forfeiture, or other condition, and the certificates representing such
shares  of  Parent  Common  Stock  may  accordingly  be  marked with appropriate
legends.  Company  shall  take  all action that may be necessary to ensure that,
from  and  after  the  Effective  Time,  Parent is entitled to exercise any such
repurchase option or other right set forth in any such restricted stock purchase
agreement  or  other  agreement.

     (b)  Cancellation  of  Parent-Owned  Stock.  Each  share  of Company Common
          --------------------------------------
Stock  held  by the Company or any direct or indirect wholly-owned subsidiary of
Company  immediately  prior  to  the  Effective  Time  shall  be  cancelled  and
extinguished  without  any  conversion  thereof.

     (c)  Contractual  Lock-up.  The  shares  of  Parent  Common Stock delivered
          ---------------------
hereby  will  be  subject to a three (3) year contractual restriction precluding
transfer, assignment, disposition, hypothecation, engaging in short sales or any
hedging  activity ("Transfer") as follows: for a period of one (1) year from the
Effective Time, no shares can be Transferred; thereafter, during each subsequent
three  month  period,  each holder can Transfer an amount equal to one-eighth of
the  shares  of  Parent  Common  Stock  issued  to  such  holder hereunder.  All
certificates  representing Parent Common Stock will contain a restrictive legend
reflecting  the  prohibition  on  Transfer.

     (d)  Capital Stock of Merger Sub.  Each share of common stock of Merger Sub
          ----------------------------
(the  "MERGER SUB COMMON STOCK") issued and outstanding immediately prior to the
Effective  Time  shall  be converted into or exercisable for one validly issued,
fully paid and nonassessable share of common stock of the Surviving Corporation.
Each certificate evidencing ownership of shares of Merger Sub Common Stock shall
evidence  ownership of such share of capital stock of the Surviving Corporation.


                                        4

     (e)  Adjustments  to  Exchange Ratios.  The exchange ratios as set forth on
          ---------------------------------
Exhibit  C  shall  be  adjusted to reflect appropriately the effect of any stock
split,  reverse  stock  split,  stock  dividend  (including  any  dividend  or
distribution  of  securities  convertible  into or exercisable for Parent Common
Stock  or  Company  Common  Stock),  reorganization,  recapitalization,
reclassification  or  other  like  change with respect to Parent Common Stock or
Company  Common  Stock  occurring  on  or after the date hereof and prior to the
Effective  Time.

     (f)  Fractional Shares.  No fraction of a share of Parent Common Stock will
          ------------------
be issued by virtue of the Merger, but in lieu thereof, each holder of shares of
Company  Common  Stock  who  would  otherwise be entitled to a     fraction of a
share  of Parent Common Stock (after aggregating all fractional shares of Parent
Common  Stock  that  otherwise  would  be  received  by such holder) shall, upon
surrender  of  such  holder's  Certificate(s)  (as  defined  in Section 1.7(c)),
receive  from  Parent, at the sole discretion of Parent, either (A) an amount of
cash (rounded to the nearest whole cent), without interest, equal to the product
of  (i)  such fraction and (ii) the average closing price of Parent Common Stock
for  the five trading days immediately preceding the last full trading day prior
to  the  Effective  Time,  as  reported on the over-the-counter market, or (B) a
whole  share  of  Parent  Common  Stock.


     1.7  SURRENDER OF CERTIFICATES; PAYMENT OF STOCK CONSIDERATION.

     (a)  Exchange  Agent.  Parent  and  Company hereby select Parent's transfer
          ----------------
agent  to  act  as  the  exchange  agent  (the  "EXCHANGE AGENT") in the Merger.

     (b)  Parent  to  Provide  Common Stock.  Promptly after the Effective Time,
          ----------------------------------
Parent  shall  make  available to the Exchange Agent, for exchange in accordance
with  this Article I, (i) the shares of Parent Common Stock issuable pursuant to
Section  1.6  in  exchange for outstanding shares of Company Preferred Stock and
Company  Common  Stock and (ii) cash in an amount sufficient for payment in lieu
of  fractional  shares  pursuant to Section 1.6(f), if any, and any dividends or
distributions to which holders of shares of Company Common Stock may be entitled
pursuant  to  Section  1.7(d).

     (c)  Exchange  Procedures.  As soon as practicable after the Effective Time
          ---------------------
(and  in  any  event  within  five  business  days after Parent's receipt of all
necessary  shareholder  lists and other supporting information including Company
stockholder  investment intent acknowledgement pursuant to section 2.21), Parent
shall  cause  the  Exchange  Agent  to  mail to each holder of record (as of the
Effective  Time)  of  a  certificate or certificates (the "CERTIFICATES"), which
immediately prior to the Effective Time represented outstanding securities whose
shares  were  converted  into the right to receive shares of Parent Common Stock
pursuant  to  Section  1.6(a), cash in lieu of any fractional shares pursuant to
Section  1.6(f)  and  any  dividends  or other distributions pursuant to Section
1.7(d),  (i) a letter of transmittal (which shall specify that delivery shall be
effected,  and  risk  of loss and title to the Certificates shall pass only upon
delivery  of the Certificates to the Exchange Agent and shall contain such other
provisions  as  Parent  may reasonably specify) and (ii) instructions for use in
effecting  the  surrender  of  the  Certificates  in  exchange  for certificates
representing  shares  of  Parent  Common  Stock,  cash in lieu of any fractional
shares  pursuant  to  Section  1.6(f),  and any dividends or other distributions
pursuant  to Section 1.7(d).  Upon surrender of Certificates for cancellation to
the  Exchange  Agent  or  to  such  other agent or agents as may be appointed by
Parent,  together  with  such  letter of transmittal, duly completed and validly
executed  in  accordance  with  the  instructions  thereto,  the holders of such
Certificates  shall  be  entitled  to receive in exchange therefore certificates
representing  the number of whole shares of Parent Common Stock into which their
shares of Company Common Stock and Company Preferred Stock were converted at the
Effective Time, payment in lieu of fractional shares which such holders have the
right  to receive pursuant to Section 1.6(f), and any dividends or distributions
payable  pursuant  to  Section 1.7(d), and the Certificates so surrendered shall
forthwith  be cancelled.  Until so surrendered, outstanding Certificates will be
deemed from and after the Effective Time, for all corporate purposes, subject to
Section  1.7(d)  as  to  the  payment  of  dividends and other distributions, to
evidence  only the ownership of the number of full shares of Parent Common Stock
into which such shares of Company Common Stock and Company Preferred Stock shall
have been so converted and the right to receive an amount in cash in lieu of the
issuance  of  any  fractional  shares  in  accordance  with  Section  1.6(f).

     (d)  Distributions  With  Respect  to  Unexchanged Shares.  No dividends or
          -----------------------------------------------------
other  distributions  declared  or  made  after  the date of this Agreement with
respect  to  Parent  Common  Stock  with  a  record  date  after  the  Effective


                                        5

Time  will  be  paid  to  the  holders  of any unsurrendered Certificate(s) with
respect  to  the  shares  of  Parent  Common Stock represented thereby until the
holders  of  record  of such Certificate(s) shall surrender such Certificate(s).
Subject  to  applicable law, following surrender of any such Certificate(s), the
Exchange  Agent shall deliver to the record holders thereof, without interest, a
certificate(s)  representing  whole  shares  of  Parent  Common  Stock issued in
exchange  therefore  along with payment in lieu of fractional shares pursuant to
Section  1.6(f)  hereof  and  the  amount  of  any  such  dividends  or  other
distributions  with  a record date after the Effective Time payable with respect
to  such  whole  shares  of  Parent  Common  Stock.

     (e)  Transfers  of  Ownership.  If  any  certificate representing shares of
          -------------------------
Parent  Common  Stock  is  to  be  issued in a name other than that in which the
Certificate  surrendered  in  exchange  therefore  is  registered,  it will be a
condition  of  the  issuance thereof that the Certificate so surrendered will be
properly endorsed and otherwise in proper form for transfer and that the persons
requesting  such exchange will have paid to Parent or any agent designated by it
any  transfer  or other taxes required by reason of the issuance of certificates
representing  shares  of  Parent Common Stock in any name other than that of the
registered  holder  of  the  Certificates  surrendered,  or  established  to the
satisfaction of Parent or any agent designated by it that such tax has been paid
or  is  not  payable.

     (f)  Required  Withholding.  Each  of  the  Exchange Agent, Parent, and the
          ----------------------
Surviving  Corporation  shall  be  entitled  to  deduct  and  withhold  from any
consideration payable or otherwise deliverable pursuant to this Agreement to any
holder or former holder of Company Common Stock and Company Preferred Stock such
amounts  as  may be required to be deducted or withheld therefrom under the Code
or  under  any  provision of state, local, or foreign tax law or under any other
applicable  legal  requirement.  To  the  extent such amounts are so deducted or
withheld, such amounts shall be treated for all purposes under this Agreement as
having  been  paid  to the person to whom such amounts would otherwise have been
paid.

     (g)  No  Liability.  Notwithstanding  anything  to  the  contrary  in  this
          --------------
Section  1.7,  none of the Exchange Agent, Parent, the Surviving Corporation, or
any  party  hereto  shall  be  liable  to  a  holder  of shares of Parent Common
Stock or Company Common Stock or Company Preferred Stock for any amount properly
paid to a public official pursuant to any applicable abandoned property, escheat
or  similar  law.

     1.8  NO FURTHER OWNERSHIP RIGHTS IN COMPANY COMMON STOCK.

     All shares of Parent Common Stock issued upon the surrender for exchange of
shares  of  Company  Common Stock and Company Preferred Stock in accordance with
the  terms  hereof  (together  with any cash paid in respect thereof pursuant to
Section  1.6(f)  and  1.7(d))  shall  be  deemed  to  have  been  issued in full
satisfaction of all rights pertaining to such shares of Company Common Stock and
Company Preferred Stock, and there shall be no further registration of transfers
on  the  records  of the Surviving Corporation of shares of Company Common Stock
and  Company  Preferred  Stock  which  were outstanding immediately prior to the
Effective Time.  If, after the Effective Time, Certificates are presented to the
Surviving  Corporation  for any reason, they shall be cancelled and exchanged as
provided  in  this  Article  I.

     1.9  LOST, STOLEN OR DESTROYED CERTIFICATES.

     In  the  event  that  any  Certificate  shall  have  been  lost,  stolen or
destroyed,  the  Exchange Agent shall issue in exchange for such lost, stolen or
destroyed  Certificate,  upon  the  making  of  an affidavit of that fact by the
holder thereof, certificates representing the shares of Parent Common Stock into
which  the shares of Company Common Stock or Company Preferred Stock represented
by such Certificates were converted pursuant to Section 1.6, cash for fractional
shares,  if any, as may be required pursuant to Section 1.6(f) and any dividends
or  distributions  payable  pursuant  to Section 1.7(d); provided, however, that
Parent  may,  in  its discretion and as a condition precedent to the issuance of
such  certificates  representing  shares  of Parent Common Stock, cash and other
distributions,  require  the owner of such lost, stolen or destroyed Certificate
to  deliver  a bond in such sum as it may reasonably direct as indemnity against
any  claim  that  may  be made against Parent, the Surviving Corporation, or the
Exchange  Agent  with  respect  to  the  Certificates alleged to have been lost,
stolen  or  destroyed.


                                        6

     1.10 TAX AND ACCOUNTING CONSEQUENCES.

     (a)  It  is intended by the parties hereto that the Merger shall constitute
a  reorganization  within the meaning of Section 368(a) of the Code. The parties
hereto  adopt this Agreement as a "plan of reorganization" within the meaning of
Sections  1.368-2(g) and 1.368-3(a) of the United States Income Tax Regulations.

     (b)  It  is  also  intended  by  the  parties  hereto that the Merger shall
qualify  for  accounting  treatment  as  a  purchase.

     1.11 DISSENTING SHARES.

     All  shares  of  Company Preferred Stock and Company Common Stock for which
appraisal  rights  are  perfected in accordance with Section 262 of Delaware Law
are  referred  to  in  this Agreement as "Dissenting Shares".  The Company shall
give  Parent  prompt  notice  upon  receipt  by  the  Company  of any demand for
appraisal  of  Company  Common Stock in connection with the Merger.  The Company
agrees  that  prior to the Effective Time it will not, except as required by law
or  with  the prior consent of Parent, voluntarily make any payment with respect
to, or settle or offer to settle, any such demand.  From and after the Effective
Time, no holder of Dissenting Shares shall be entitled to vote Dissenting Shares
for  any  purposes  or to receive payment of dividends or other distributions on
the  Dissenting  Shares  (except  dividends  or  other  distributions payable to
stockholders of record at the date which is prior to the Effective Time), unless
otherwise  provided  by  Section  262(k)  of  the  DGCL.

     1.12 TAKING OF NECESSARY ACTION; FURTHER ACTION.

     If,  at  any time after the Effective Time, any further action is necessary
or  desirable  to  carry  out  the  purposes  of  this Agreement and to vest the
Surviving  Corporation  with  full  right,  title, and possession to all assets,
property,  rights,  privileges, powers and franchises of Company and Merger Sub,
the officers and directors of Company and Merger Sub are fully authorized in the
manner of their respective corporations or otherwise to take, and will take, all
such  lawful  and  necessary  action.

                                   ARTICLE II

                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY

     The  Company  represents  and warrants to Parent and Merger Sub, subject to
such exceptions as are specifically disclosed in writing in the schedules hereto
(each such exception to reference the specific section number of this Article II
to  which  it  applies  and  each other section number of this Article II to the
extent such applicability is reasonably apparent on the face of such exception),
dated  as  of  the  date  hereof  (the  "COMPANY  SCHEDULE"):

     2.1  ORGANIZATION OF COMPANY; NO SUBSIDIARIES.

     (a)  Company  is a corporation duly organized, validly existing and in good
standing  under  the  laws  of  the  jurisdiction  of its incorporation; has the
corporate  power and authority to own, lease and operate its assets and property
and  to  carry  on  its  business  as  now being conducted and as proposed to be
conducted;  and  is  duly  qualified  to  do  business and in good standing as a
foreign corporation in each jurisdiction in which the failure to be so qualified
would  have  a  Material  Adverse  Effect  (as defined in Section 9.3(b)(ii)) on
Company.

     (b)  Company  does  not  own  any  subsidiaries.  Except  as  set  forth in
Schedule  2.1(b)  of  the  Company  Schedule,  Company  does  not own an equity,
membership,  partnership,  or  similar  interest in, or any interest convertible
into,  or exchangeable or exercisable for any such interest in, any corporation,
partnership,  joint  venture,  limited  liability  company  or  other  business
association  or  entity.

     (c)  Schedule  2.1(c)  of  the Company Schedule contains a true and correct
copy  of the Certificate of Incorporation and Bylaws of Company, each as amended
to  date,  and each such instrument is in full force and effect.  Company is not
in  violation  of  any  of the provisions of its Certificate of Incorporation or
Bylaws.


                                        7

     2.2  COMPANY CAPITAL STRUCTURE.

     The  authorized  capital  stock of Company consists of 20,000,000 shares of
Company  Common  Stock,  of  which  there  were  2,575,625  shares  issued  and
outstanding as of the date hereof, and 11,500,000 shares of preferred stock, par
value  $.001 per share, of which 6,804,349 shares of Company Preferred Stock are
issued  or outstanding as of the date hereof.  All outstanding shares of Company
Common  Stock  and  Company Preferred Stock are duly authorized, validly issued,
fully  paid, and nonassessable, and are not subject to preemptive rights created
by  statute,  the  Certificate  of  Incorporation  or  Bylaws of Company, or any
agreement  or  document to which Company is a party or by which it is bound.  As
of  the  date  hereof,  there are warrants to purchase 800,000 shares of Company
Common  Stock  ("COMPANY  WARRANTS") outstanding and options to purchase 840,000
shares  of  Company Common Stock ("COMPANY OPTIONS") outstanding.  The Company's
2001  Stock  Option Plan has a total of 2,630,000 shares of Company Common Stock
reserved for issuance pursuant to such plan.  All shares of Company Common Stock
subject  to  issuance  as  aforesaid,  upon issuance on the terms and conditions
specified  in the instruments pursuant to which they are issuable, would be duly
authorized,  validly issued, fully paid, and nonassessable.  Schedule 2.2 of the
Company  Schedule  lists  (i) each outstanding share of Company Common Stock and
Company Preferred Stock, the name of the holder of such security and the vesting
schedule  for such security, if applicable, (ii) each outstanding Company Option
to  acquire  shares  of  Company  Common  Stock,  the name of the holder of such
option,  the number of shares subject to such option, the exercise price of such
option,  the  number  of shares as to which such option will have vested at such
date,  the  vesting  schedule  for such option and whether the exercisability of
such  option  will be accelerated in any way by the transactions contemplated by
this  Agreement  or  for  any  other  reason,  and  indicates  the  extent  of
acceleration,  if  any, and (iii) each outstanding Company Warrant,  the name of
the holder of such Company Warrant, the number of shares subject to such Company
Warrant,  the exercise price of such Company Warrant, the number of shares as to
which  such  Company Warrant will have vested at such date, the vesting schedule
for  such Company Warrant and whether the exercisability of such Company Warrant
will  be  accelerated  in  any  way  by  the  transactions  contemplated by this
Agreement  or for any other reason, and indicates the extent of acceleration, if
any.

     2.3  OBLIGATIONS WITH RESPECT TO CAPITAL STOCK.

     Except as set forth in Schedule 2.3 of the Company Schedule, as of the date
hereof,  there  are  no  equity  securities,  partnership  interests, or similar
ownership  interests of any class of the Company, or any securities exchangeable
or  convertible  into  or  exercisable  for  such equity securities, partnership
interests,  or  similar  ownership  interests  issued,  reserved for issuance or
outstanding.  Except  for  securities  the  Company  owns,  there  are no equity
securities,  partnership  interests, or similar ownership interests of any class
of  any  subsidiary  of the Company, or any security exchangeable or convertible
into or exercisable for such equity securities, partnership interests or similar
ownership interests issued, reserved for issuance or outstanding.  Except as set
forth  in  Schedule 2.3 of the Company Schedule, there are no stock appreciation
rights,  phantom  stock,  or other similar rights of the Company and no options,
warrants,  equity  securities,  partnership  interests,  or  similar  ownership
interests,  calls,  rights  (including  preemptive  rights),  commitments  or
agreements  of  any  character  to which Company or any of its subsidiaries is a
party,  or  by  which  it  is  bound,  obligating  the  Company  or  any  of its
subsidiaries  to  issue,  deliver  or  sell, or cause to be issued, delivered or
sold,  or  repurchase,  redeem  or  otherwise  acquire, or cause the repurchase,
redemption  or  acquisition, of any shares of capital stock of Company or any of
its  subsidiaries  or  obligating  Company  or any of its subsidiaries to grant,
extend,  accelerate  the  vesting  of  or enter into any such stock appreciation
rights,  phantom  stock,  or  other similar rights, or any such option, warrant,
equity  security,  partnership  interest  or  similar  ownership interest, call,
right,  commitment  or  agreement.  There are no registration rights and, to the
knowledge  of  the  Company there are no voting trusts, rights of first refusal,
proxies  or  other  agreements  or  understandings  with  respect  to any equity
security  of  any  class  of the Company or with respect to any equity security,
partnership  interest  or  similar ownership interest of any class of any of its
subsidiaries.

     2.4  AUTHORITY.

     (a)  The  Company  has all requisite corporate power and authority to enter
into this Agreement and to consummate the transactions contemplated hereby.  The
execution  and  delivery  of  this  Agreement  and  the  consummation  of  the
transactions  contemplated  hereby  have  been  duly authorized by all necessary
corporate  action  on  the  part  of  Company,  subject only to the approval and
adoption  of  this  Agreement  and  the  approval  of  the  Merger  by Company's
shareholders  and  the  filing  and  recordation  of  the  Certificate of Merger
pursuant  to  Delaware  Law.


                                        8

This Agreement has been duly executed and delivered by Company and, assuming the
due authorization, execution, and delivery by Parent and Merger Sub, constitutes
the valid and binding obligations of Company, enforceable in accordance with its
terms,  except  as enforceability may be limited by bankruptcy and other similar
laws  and  general  principles  of  equity.  The  execution and delivery of this
Agreement  by Company does not, and the performance of this Agreement by Company
will  not,  (i)  conflict  with  or  violate the Certificate of Incorporation or
Bylaws  of  Company,  (ii)  subject  to  obtaining the approval of the Merger by
Company's  shareholders  as  contemplated in Section 5.2 and compliance with the
requirements  set  forth  in  Section 2.4(b) below, conflict with or violate any
law,  rule,  regulation, order, judgment, or decree applicable to Company or any
of  its  subsidiaries  or  by which its or any of their respective properties is
bound  or  affected,  or  (iii)  except  as set forth on Schedule 2.4 (a) of the
Company  Schedule, result in any breach of, or constitute a default (or an event
that  with  notice  or  lapse of time or both would become a default)  under, or
impair  Company's  rights  or alter the rights or obligations of any third party
under,  or give to others any rights of termination, amendment, acceleration, or
cancellation  of,  or  result in the creation of a lien or encumbrance on any of
the  properties or assets of Company or any of its subsidiaries pursuant to, any
note,  bond,  mortgage,  indenture, contract, agreement, lease, license, permit,
franchise,  or  other  instrument  or  obligation to which Company or any of its
subsidiaries is a party or by which Company or any of its subsidiaries or its or
any  of  their respective properties are bound or affected, except to the extent
such conflict, violation, breach, default, impairment or other effect could not,
in  the  case  of  clause  (ii)  or  (iii),  individually  or  in the aggregate,
reasonably  be  expected  to  have  a  Material  Adverse  Effect on Company or a
material  adverse  effect  on  the ability of Company to perform its obligations
under  this  Agreement.

     (b)  No  consent,  approval,  order  or  authorization of, or registration,
declaration,  or  filing  with any court, administrative agency or commission or
other  governmental  authority  or  instrumentality  ("GOVERNMENTAL  ENTITY") is
required  by  or  with  respect  to Company in connection with the execution and
delivery  of this Agreement or the consummation of the transactions contemplated
hereby  or  thereby, except for (i) the filing of the Certificate of Merger with
the  Secretary  of  State  of  Delaware,  and  (ii)  such  other  consents,
authorizations,  filings, approvals, and registrations which, if not obtained or
made,  could  not,  individually  or in the aggregate, reasonably be expected to
have  a  Material  Adverse Effect on Company or a material adverse effect on the
ability  of  Company  to  perform  its  obligations  under  this  Agreement.

     2.5  COMPANY FINANCIAL STATEMENTS.

     (a)  The  Company has delivered to Parent in Schedule 2.5(a) of the Company
Schedule  copies  of its financial statements from February 16, 2001 (inception)
through  August  31,  2004 (the "COMPANY FINANCIALS").  The balance sheet of the
Company  contained  in  the financial statements of the Company as of August 31,
2004  is  hereinafter  referred  to as the "COMPANY BALANCE SHEET."  The Company
Financials  were  prepared  in  accordance  with  generally  accepted accounting
principles  ("GAAP")  applied  on  a  consistent  basis  throughout  the periods
involved  (except  as  may  be indicated in the notes thereto or, in the case of
unaudited  interim  financial  statements  as  may  be permitted by GAAP.).  The
Company  Financials  fairly  present  in  all  material  respects  the financial
position of the Company and its subsidiaries to which it relates as of its date,
and  each  of  the  related  consolidated  statements of operations and retained
earnings  and  cash  flows  or  equivalent  statements in the Company Financials
(including  any  related  notes  and  schedules) fairly presents in all material
respects  the  results  of  operations, retained earnings and cash flows, as the
case  may  be,  of  the  Company  and  its subsidiaries for the period set forth
therein in each case in accordance with generally accepted accounting principles
applicable  to the Company consistently applied throughout the periods involved,
except  as  may  be  noted  therein.  The  accounts  receivable  and  any  other
contingent  asset  reflected  on  the Company Balance Sheet arose from bona fide
transactions  in  the  ordinary  course  of  business,  and,  to the best of the
Company's  Knowledge,  are  not  subject  to  any  offset  or  counterclaim.

     (b)  The  Company has delivered to Parent in Schedule 2.5(b) of the Company
Schedule  the  current balance of all asset accounts and detail accounts payable
on  the  Company's  general  ledger  as  of  September  29,  2004.

     (c)  Except  as  disclosed  in the Company Financials or Schedule 2.5(c) of
the  Company  Schedule,  neither  Company  nor  any  of its subsidiaries has any
liabilities (absolute, accrued, contingent or otherwise) of a nature required to
be  disclosed  on  a  balance  sheet or in the related notes to the consolidated
financial statements prepared in accordance with GAAP which are, individually or
in  the  aggregate, material to the business, results of operations or financial
condition  of  Company and its subsidiaries taken as a whole, except liabilities
(i)  provided  for


                                        9

in  the  Company  Balance  Sheet, or (ii) incurred since the date of the Company
Balance  Sheet  in  the  ordinary  course  of business and are immaterial in the
aggregate.

     2.6  ABSENCE OF CERTAIN CHANGES OR EVENTS.

     Except as set forth in Schedule 2.6 of the Company Schedule, since the date
of the Company Balance Sheet there has not been: (i) any Material Adverse Effect
on  the Company,  (ii) any declaration, setting aside or payment of any dividend
on,  or other distribution  (whether in cash, stock, or property) in respect of,
any  of  the  Company's  capital  stock,  or  any  purchase, redemption or other
acquisition  by  the  Company of any of the Company's capital stock or any other
securities  of  the Company or any options, warrants, calls or rights to acquire
any  such  shares  or  other  securities,  (iii)  any  split,  combination,  or
reclassification of any of the Company's capital stock, (iv) any granting by the
Company  of  any  increase in compensation or fringe benefits, or any payment by
the  Company  or  any  of its subsidiaries of any bonus, (v) any granting by the
Company  of  any increase in severance or termination pay, (vi) any entry by the
Company  into  any  currently  effective  employment,  severance, termination or
indemnification  agreement  or  any  other  agreement  the benefits of which are
contingent or the terms of which are materially altered upon the occurrence of a
transaction involving the Company of the nature contemplated hereby, (vii) entry
by  the  Company  into  any  licensing  or  other  agreement  with regard to the
acquisition  or  disposition  of  any Intellectual Property (as defined herein),
(viii) any  material change by the Company in its accounting methods, principles
or  practices,  except  as  required  by  concurrent  changes  in GAAP, (ix) any
revaluation  by the Company of any of its assets, including, without limitation,
writing down the value of capitalized inventory or writing off notes or accounts
receivable,  (x)  any  changes  in  the vesting schedules of outstanding Company
Options  or Company Warrants, or (xi) any grant of Company derivative securities
prior  to  the  date  of  this  Agreement.

     2.7  TAXES.

     Definition  of Taxes.  For the purposes of this Agreement, "TAX" or "TAXES"
     ---------------------
refers to any and all federal, state, local, and foreign taxes, assessments, and
other  governmental  charges,  duties,  impositions, and liabilities relating to
taxes,  including  taxes  based  upon  or  measured  by  gross receipts, income,
profits,  sales,  use  and  occupation,  and value added, ad  valorem, transfer,
franchise,  withholding,  payroll,  recapture,  employment,  excise and property
taxes,  together with all interest, penalties and additions imposed with respect
to  such  amounts  and  any     obligations under any agreements or arrangements
with  any  other person with respect to such amounts and including any liability
for  taxes  of  a  predecessor  entity.

     2.8  TAX RETURNS AND AUDITS.

     (a)  Company  has  timely  filed  all  federal,  state,  local  and foreign
returns,  estimates,  information  statements  and  reports  ("RETURNS")  and/or
extensions  relating  to  Taxes  required  to  be  filed by Company with any Tax
authority,  except  such Returns which are not material to the Company.  Company
has  paid  all  Taxes  shown  to  be  due  on  such  Returns.

     (b)  Company  as  of  the Effective Time will have withheld with respect to
its  employees all federal and state income Taxes, Taxes pursuant to the Federal
Unemployment  Tax  Act,  and  other  Taxes  required  to  be  withheld.

     (c)  Company has not been delinquent in the payment of any material Tax nor
is  there  any material Tax deficiency outstanding, proposed or assessed against
Company,  nor  has  Company  executed  any  unexpired  waiver  of any statute of
limitations  on  or extending the period for the assessment or collection of any
Tax.

     (d)  No  audit  or  other  examination  of any Return of Company by any Tax
authority is presently in progress, nor has Company been notified of any request
for  such  an  audit  or  other  examination.

     (e)  No  adjustment  relating  to  any  Returns  filed  by Company has been
proposed  in  writing  formally or informally by any Tax authority to Company or
any  representative  thereof.

     (f)  Company  has  no liability for any material unpaid Taxes which has not
been  accrued  for or reserved on Company Balance Sheet in accordance with GAAP,
whether  asserted  or  unasserted,  contingent  or  otherwise.


                                       10

     (g)  There  is no contract, agreement, plan or arrangement to which Company
is  a  party  as of the date of this Agreement, including but not limited to the
provisions  of  this  Agreement,  covering  any  employee  or former employee of
Company that, individually or collectively, would reasonably be expected to give
rise  to  the  payment  of  any  amount that would not be deductible pursuant to
Sections  280G,  404  or  162(m)  of the Code.  There is no contract, agreement,
plan,  or  arrangement  to  which  Company is a party or by which it is bound to
compensate  any individual for excise taxes paid pursuant to Section 4999 of the
Code.

     (h)  Company  has  not  filed any consent agreement under Section 341(f) of
the  Code  or  agreed  to  have  Section  341(f)(2)  of  the  Code  apply to any
disposition  of  a  subsection (f) asset (as defined in Section 341(f)(4) of the
Code)  owned  by  Company.

     (i)  Company is not a party to and has no obligation under any Tax-sharing,
Tax  indemnity  or  Tax  allocation  agreement  or  arrangement.

     (j)  None  of  Company's  assets  are  tax-exempt  use  property within the
meaning  of  Section  168(h)  of  the  Code.

     (k)  Company has (a) never been a member of an affiliated group (within the
meaning of Code Section 1504(a)) filing a consolidated federal income Tax Return
(other than a group the common parent of which was Company), (b) with respect to
the  Taxes of any person (other than Company) (i) no liability under Treas. Reg.
Section  1.1502-6  (or any similar provision of state, local or foreign law) and
(ii) no material     liability as a transferee or successor and (c) never been a
party  to  any  joint  venture,  partnership  or  other agreement that should be
treated  as  a  partnership  for  Tax  purposes.

     (l)  Company  has  not  been  either  a  "distributing  corporation"  or  a
"controlled  corporation"  in  a  distribution  of stock qualifying for tax-free
treatment  under  Section  355  of  the  Code.

     2.9  COMPANY  INTELLECTUAL  PROPERTY.

     For  the purposes of this Agreement, the following terms have the following
definitions:

     "INTELLECTUAL  PROPERTY"  shall  mean  any  or all of the following and all
rights  in,  arising out of, or associated therewith: (i) including any licenses
or  sublicenses  (and  subsequent amendments thereto) to any Patents (as defined
below)  or other Intellectual Property (ii) all United States, international and
foreign  patents  and  applications  therefore  and  all  reissues,  divisions,
renewals,  extensions,  provisionals,  continuations  and  continuations-in-part
thereof ("Patents"); (iii) all inventions (whether patentable or not), invention
disclosures,  improvements,  trade  secrets,  proprietary information, know how,
technology, technical data and customer lists, and all documentation relating to
any  of  the  foregoing;  (iv)  all  copyrights,  copyrights  registrations  and
applications  therefore,  and  all other rights corresponding thereto throughout
the  world;  (v)  all  industrial designs and any registrations and applications
therefore  throughout  the  world;  (vi)  all  trade  names,  logos,  common law
trademarks  and  service  marks,  trademark  and  service mark registrations and
applications  therefore  throughout  the  world;  (vii)  all  databases and data
collections  and  all  rights therein throughout the world; (viii) all moral and
economic  rights  of  authors and inventors, however denominated, throughout the
world,  and  (ix)  any  similar  or  equivalent  rights  to any of the foregoing
anywhere  in  the  world.  "COMPANY  INTELLECTUAL  PROPERTY"  shall  mean  any
Intellectual Property that is owned by the Company, as set forth on Schedule 2.9
of  the  Company  Schedule,  including but not limited to, the License Agreement
(and  all  subsequent  amendments  thereto)  by  and  between  Baylor College of
Medicine  ("Baylor")  and  Company  signed  on  September  5, 2001 (the "License
Agreement")  attached  hereto  in  Schedule  2.9  of  the  Company  Schedule.

     (a)  Except  as  set  forth  in  Schedule  2.9 of the Company Schedule, the
Company  does  not  own  or  have  pending,  nor  has  it  licensed, any Company
Intellectual  Property.  No  Company Intellectual Property or product or service
of  Company is subject to any proceeding or outstanding decree, order, judgment,
contract,  license, agreement, or stipulation restricting in any manner the use,
transfer, or licensing thereof by Company, or which may affect the validity, use
or  enforceability  of  such  Company  Intellectual  Property.


                                       11

     (b)  To  the  knowledge  of  Company, Company owns, or has license or other
rights  to  use  each  material  item  of Company Intellectual Property or other
Intellectual Property used by Company free and clear of any lien or encumbrance.

     (c)  Neither  Company nor any of its subsidiaries has transferred ownership
of  or granted any license with respect to, any Company Intellectual Property to
any  third  party.

     (d)  To  the knowledge of Company, the operation of the business of Company
and  its  subsidiaries as such business currently is conducted does not infringe
the  Intellectual  Property  of  any  third  party.

     (e)  Neither  Company  nor any of its subsidiaries has received notice from
any  third  party  that  the  operation of the business of Company or any of its
subsidiaries  or  any  act,  product,  or  service  of  Company  or  any  of its
subsidiaries,  infringes  the  Intellectual  Property  of  any  third  party.

     (f)  To  the  knowledge  of  Company,  no  person  has or is infringing any
material  Company  Intellectual  Property.

     (g)  Company  and  each  of  its subsidiaries has taken reasonable steps to
protect  Company's  and  its  subsidiaries'  rights  in  Company's  confidential
information  and trade secrets that it wishes to protect or any trade secrets or
confidential  information  of  third  parties  provided to Company or any of its
subsidiaries,  and,  without  limiting  the  foregoing,  each of Company and its
subsidiaries has and enforces a policy requiring each employee and contractor to
execute  a  proprietary  information/confidentiality  agreement  or  contractor
agreement  which  includes  a proprietary/information or confidential provision,
both substantially in the form set forth in Schedule 2.9 of the Company Schedule
and  all  current and former employees and contractors of Company and any of its
subsidiaries  have  executed  such  an  agreement.

     (h)  Company  has  met every obligation and/or condition as required by any
agreement involving Company Intellectual Property, including, but not limited to
the License Agreement, and is not and has not at any time breached any agreement
involving  Company  Intellectual  Property,  including,  but  not limited to the
License  Agreement.

     (i)  To  the  knowledge  of Company, Baylor is not in breach of the License
Agreement  and  has not notified the Company of any breach by the Company of the
License  Agreement  and  except  as  set  forth  in  Schedule 2.9 of the Company
Schedule;  Baylor  has not taken any action inconsistent with its conditions and
obligations.

     2.10 COMPLIANCE; PERMITS; RESTRICTIONS.

     (a)  Except  as  set  forth  on  Schedule 2.10 (a) of the Company Schedule,
Company  is  not  in  any  material  respect  in conflict with, or in default or
violation  of  (i)  any  law,  rule,  regulation,  order,  judgment,  or  decree
applicable  to  Company  or  by which its or any of its respective properties is
bound  or  affected,  or  (ii)  any  material  note,  bond, mortgage, indenture,
contract,  agreement,  lease, license, permit, franchise, or other instrument or
obligation  to which Company is a party or by which Company or its properties is
bound  or  affected.  To the knowledge of Company, no investigation or review by
any  Governmental  Entity  is pending or threatened against Company, nor has any
Governmental  Entity  indicated  an  intention to conduct the same.  There is no
material  agreement, judgment, injunction, order, or decree binding upon Company
which  has  or would reasonably be expected to have the effect of prohibiting or
materially  impairing  any current business practice of Company, any acquisition
of  material  property  by  Company  or  the  conduct  of business by Company as
currently  conducted.

     (b)  Company  holds  all  permits, licenses, variances, exemptions, orders,
and  approvals from governmental authorities which are material to the operation
of  the  business  of  Company,  as set forth in Schedule 2.10(b) of the Company
Schedule (collectively, the "COMPANY PERMITS").  Company is in compliance in all
material  respects  with  the  terms  of  the  Company  Permits.

     (c)  Company  has  not received any major adverse written notice within the
past  five  years  from  any  authority  responsible  for  the regulation of the
manufacture of pharmaceuticals (the "Food and Drug Authority") (i) regarding the
approvability  or  approval  of  a  permit  concerning,  or the labeling of, any
products  of  the  Company  or


                                       12

(ii)  alleging  any violation of any applicable law governing the manufacture of
pharmaceuticals  ("FOOD  AND  DRUG  LAWS")  by the Company which, in the case of
either  clause  (i)  or  (ii), individually or in the aggregate has had or would
have  a  material adverse effect on the Company. Schedule 2.10(c) of the Company
Schedule  sets  forth all of the permits, licenses, variance, exemptions, orders
and  approvals  from  governmental authorities issued to the Company by any Food
and  Drug  Authority.

     (d)  No  permit, permission for clinical testing, or product of the Company
has  been  denied,  placed  on  hold, withdrawn, suspended, or discontinued as a
result  of  any action by any Food and Drug Authority, by the Company within the
past  five  years.  No  proceedings  of which the Company has knowledge (whether
completed  or  pending)  seeking  the  withdrawal, suspension, or seizure of any
permit, or product of the Company are pending against the Company, the Company's
products,  any  licensee  or  customer  of  any  product  of  the  Company.

     (e)  For  products that the Company is currently manufacturing, testing, or
subjecting  to  clinical  evaluation,  each  of the Company's applicable permits
under  the  Food  and  Drug  Laws  is  complete, accurate, and up to date in all
material  respects.

     (f)  To the Company's Knowledge, (i) during the last five years no officer,
employee,  or  agent  of the Company, has made an untrue statement of a material
fact  or fraudulent statement to any Food and Drug Authority, failed to disclose
a  material  fact  required  to  be disclosed to any Food and Drug Authority, or
committed  an  act, made a statement, or failed to make a statement that, at the
time  such  disclosure was made, could reasonably be expected to provide a basis
for any Food and Drug Authority to invoke with respect to the Company its policy
with  respect to fraud, untrue statements of material facts, bribery, or illegal
gratuities,  nor  (ii)  has  any officer, employee, or agent of the Company been
convicted of any crime or engaged in any conduct for which debarment is mandated
by or any applicable law. Further, to the Company's Knowledge no employee of the
Company  has  been  debarred,  suspended,  or  denied approval to participate in
activities subject to regulation by the U.S. Food and Drug Administration or any
comparable  agency  of  any  foreign  jurisdiction.

     (g)  The  Company  has not received any written notice within the past five
years  that  any Food and Drug Authority has commenced or overtly threatened any
action  to  enjoin production or clinical evaluation of any product manufactured
or  proposed  to  be  manufactured  by  the  Company.

     2.11 LITIGATION.

     As  of  the date of this Agreement, except as set forth in Schedule 2.11 of
the  Company Schedule, there is no action, suit, proceeding, claim, arbitration,
or  investigation pending, or as to which Company or any of its subsidiaries has
received  any  notice  of  assertion  nor,  to  Company's  knowledge, is there a
threatened  action,  suit,  proceeding,  claim,  arbitration,  or  investigation
against  Company  or any of its subsidiaries which in each case reasonably would
be  likely to be material to Company, or which in any manner challenges or seeks
to prevent, enjoin, alter, or delay any of the transactions contemplated by this
Agreement.

     2.12 BROKERS' AND FINDERS' FEES.

     Company  has  not  incurred, nor will it incur, directly or indirectly, any
liability  for  brokerage or finders' fees or agents' commissions or any similar
charges  in  connection  with  this  Agreement  or  any transaction contemplated
hereby.

     2.13 EMPLOYEE BENEFIT PLANS AND COMPENSATION

     (a)  Company  does  not  contribute to any pension, profit-sharing, option,
other incentive plan, or other Employee Benefit Plan (as defined in Section 3(3)
of  the  Employee Retirement Income Security Act of 1974), has any obligation to
or  customary  arrangement  with  employees for bonuses, incentive compensation,
vacations,  severance  pay,  insurance,  or other benefits, or any agreements or
offer  letters  with  any  employee, except as set forth in Schedule 2.13 of the
Company  Schedule.


                                       13

     (b)  Company  is in compliance in all material respects with all applicable
material  foreign,  federal,  state  and  local  laws,  rules  and  regulations
respecting  employment, employment practices, terms and conditions of employment
and  wages  and  hours.

     (c)  Neither  the  execution  and  delivery  of  this  Agreement  nor  the
consummation  of  the  transactions  contemplated  hereby will (i) result in any
payment (including severance, unemployment compensation, golden parachute, bonus
or  otherwise)  becoming due to any shareholder, director or Company employee or
any  of  its  subsidiaries  under  any agreement or otherwise, (ii) increase any
benefits  otherwise  payable  under  any  agreement,  or  (iii)  result  in  the
acceleration  of the time of payment or vesting of any such benefits, except the
acceleration and exercise or termination  of the Company Options as contemplated
by  Section  4.1.

     (d)  Company Schedule 2.13 lists the current annualized salary/compensation
paid  to  each  Company  employee  and  consultant.

     2.14 ABSENCE OF LIENS AND ENCUMBRANCES.

     Except  as  disclosed in Schedule 2.14 of the Company Schedule, the Company
has  good  and  marketable title to, or, in the case of leased properties, valid
leasehold  interests  in,  insured  with  respect to properties and assets which
currently  are  of  a  type for which insurance is generally available, free and
clear (except as indicated in the Company Schedule or in the most recent Company
Financials and liens for current taxes not yet due and payable), of all security
interests,  liens,  encumbrances  and encroachments of a material nature, to its
real  property  and other property and assets that are material to the Company's
business.  Schedule  2.14  of  the  Company Schedule sets forth the location and
legal  description  of each parcel of real property owned, leased or utilized by
the  Company.

     The  Company  has  good  and marketable title to all of its assets, whether
real,  personal, mixed, tangible, or intangible, which constitute all the assets
and  interests  in  assets  that  are  used  in  the business as it is presently
conducted.  All  of  the assets are free and clear of mortgages, liens, pledges,
charges,  encumbrances,  equities,  claims, easements, rights of way, covenants,
conditions,  or  restrictions,  except  for  (a)  those disclosed in the Company
Financials  or in the Disclosure Schedule; (b) the lien of current taxes not yet
due  and payable; and (c) possible minor matters that, in the aggregate, are not
substantial  in  amount and do not materially detract from or interfere with the
present  or  intended  use  of any of these assets or materially impair business
operations.  The Company is not in default or in arrears in any material respect
under  any  lease  of  property  used  in  the  business.  All tangible personal
property  of  the  Company is in reasonably good operating condition and repair,
ordinary  wear  and  tear  excepted.

     2.15 ENVIRONMENTAL MATTERS.

     (a)  Except  as  would  not  reasonably  be  likely to result in a Material
Adverse  Effect  on Company, (i) Company has not generated, transported, stored,
used,  manufactured, disposed of, released or exposed its employees or others to
pollutants,  contaminants,  wastes,  or  any  toxic,  radioactive  or  otherwise
hazardous materials ("HAZARDOUS MATERIALS") in violation of, or in a manner that
would  be  reasonably likely to result in liability under, any rule, regulation,
treaty  or  statute  promulgated  by any Governmental Entity in effect as of the
date  hereof  to  protect  the  environment  or to prohibit, regulate or control
Hazardous  Materials ("ENVIRONMENTAL LAWS") and (ii) no Hazardous  Materials are
located  in,  on or under any real property or facility now or previously owned,
leased or operated by Company or any of its subsidiaries in a manner which would
reasonably  be  expected  to  result  in liability under, or a violation of, any
Environmental  Law.

     (b)  Except for matters which would not reasonably be expected to result in
a  Material  Adverse  Effect  on  Company,  no  action,  proceeding,  revocation
proceeding, amendment procedure, writ, injunction or claim is     pending, or to
Company's  knowledge,  threatened  concerning any Company Permit relating to any
environmental  matter,  or  otherwise  relating  to  any  Environmental  Law.

     2.16 LABOR MATTERS.

     (i) There are no controversies pending or, to the knowledge of the Company,
threatened,  between  Company  and  any  of  its  employees  or  independent
contributors;  (ii)  as of the date of this Agreement, Company is not a party to
any  collective bargaining agreement or other labor union contract applicable to
persons  employed  by  Company


                                       14

nor  does  Company  know  of any activities or proceedings of any labor union to
organize any such employees; and (iii) as of the date of this Agreement, Company
has  no  knowledge  of  any  strikes,  slowdowns, work stoppages or lockouts, or
threats  thereof,  by  or  with  respect  to  any  employees  of  Company.

     2.17 AGREEMENTS, CONTRACTS, AND COMMITMENTS.

     As  of  the date hereof, except as provided in Schedule 2.17 of the Company
Schedule,  Company  is  not  a  party  to  and  is  not  bound  by:

     (a)  (i)  any  employment,  consulting,  director  or advisory board member
agreement,  contract  or  commitment  with any officer, advisory board member or
director  or  higher  level  employee or member of Company's Board of Directors,
(ii)  any  such agreement, contract or commitment with any employee, consultant,
director, advisory board member, shareholder or other person that will result in
any  obligation  of Company or any of its subsidiaries to make any payments as a
result  of  the  transactions  contemplated hereby, (iii) any agreement with any
employee, consultant, director, advisory board member, or shareholder of Company
pursuant  to  which Company has loaned or is obligated to loan any money thereto
or (iv) any agreement or arrangement providing for severance or termination pay;

     (b)  any agreement or plan, including, without limitation, any stock option
plan,  warrant  agreement, stock appreciation right plan or stock purchase plan,
any  of  the  benefits of which will be increased, or the vesting of benefits of
which  will  be  accelerated,  by  the  occurrence  of  any  of the transactions
contemplated by this Agreement or the value of any of the benefits of which will
be  calculated  on  the  basis  of  any of the transactions contemplated by this
Agreement,  except  the  acceleration and exercise or termination of the Company
Options  as  contemplated  by  Section  4.1;

     (c)  any  agreement  of indemnification of officers, directors or employees
of  Company, except as provided for in Company's Certificate of Incorporation or
Bylaws,  or  any  guaranty  of  third  party  indebtedness  or of obligations of
officers,  directors,  employees  or  agents  of  Company;

     (d)  any agreement, contract or commitment containing any covenant limiting
in  any respect the right of Company or any of its subsidiaries to engage in any
line  of  business  in  any geographic area or to compete with     any person or
granting  to  any  person  any  interest  in  Company's  distribution  rights;

     (e)  any  agreement,  contract or commitment currently in force relating to
the  disposition or acquisition by Company after the date of this Agreement of a
material  amount of assets not in the ordinary course of business or pursuant to
which  Company  has  any  material  ownership  interest  in  any  corporation,
partnership,  joint  venture  or  other  business  enterprise;

     (f)  any  agreement,  contract  or  commitment  containing  exclusivity
provisions  pursuant  to  which  Company has agreed not to purchase the goods or
services  of,  or  enter  into  a  commercial relationship with, another person;

     (g)  any  mortgages,  indentures,  guarantees,  loans or credit agreements,
security agreements or other agreements or instruments relating to the borrowing
of  money  or  extension  of  credit;

     (h)  any  settlement  agreement  relating  to  any  claim  or  suit;

     (i)  any  real  property  lease;

     (j)  any  other agreement or contract that contains a non-compete provision
or  a  confidentiality  provision  binding  on  the  Company;  or

     (k)  any  other  agreement,  lease,  contract  or  commitment that involves
remaining  obligations  of  Company  of  $10,000  or  more  individually  or
collectively.


                                       15

Neither  Company  nor,  to  Company's  knowledge,  any  other party to a Company
Contract  (as  defined  below),  is  in  breach, violation or default under, and
Company  has  not  received  written  notice  that  it has breached, violated or
defaulted  under,  any  of  the  terms  or  conditions of any of the agreements,
contracts  or  commitments  to  which Company is a party or by which it is bound
that  are  required to be disclosed in the Company Schedule (any such agreement,
contract  or  commitment, a "COMPANY CONTRACT") in such a manner as would permit
any  other  party  to  cancel  or  terminate any such Company Contract, or would
permit  any  other  party to seek material damages or other remedies (for any or
all  of  such breaches, violations or defaults, in the aggregate).  Further, the
Company  has  not breached any of the terms of the Confidentiality Agreement (as
defined  in  section  5.3).

     2.18 INSURANCE.

     There  is  no  material claim by Company or any of its subsidiaries pending
under  any  of  the  insurance  policies and fidelity bonds covering the assets,
business,  equipment,  properties, operations, employees, officers and directors
of Company and its subsidiaries as to which coverage has been questioned, denied
or  disputed  by  the  underwriters  of  such policies or bonds. The Company has
insurance coverage as required by the License Agreement and any other agreement,
including  all  agreements listed on Schedule 2.17 of the Company Schedule, such
insurance  coverage  has  been  previously  provided  to  Parent.

     2.19 BOARD APPROVAL.

     The  Board  of  Directors of Company has, as of the date of this Agreement,
(i)  determined that the Merger is fair to, advisable, and in the best interests
of  Company  and  its  shareholders  (ii)  determined  to  recommend  that  the
shareholders  of  Company  approve  this Agreement, and  (iii) duly approved the
Merger,  this  Agreement,  and  the  transactions  contemplated  hereby.

     2.20 STATE TAKEOVER STATUTES.

     The  Board  of  Directors  of Company has taken all actions so that (i) the
restrictions  contained  in  Section  203  of  the  Delaware Law applicable to a
"business  combination"  (as  defined in such Section 203) will not apply to the
execution,  delivery  or performance of this Agreement or to the consummation of
the  Merger  or the other transactions contemplated by this Agreement.  No other
state  takeover  statute or similar statute or regulation applies to or purports
to  apply  to  the  Merger, this Agreement, the Company Voting Agreements or the
transactions  contemplated  hereby  and  thereby.

     2.21 INVESTMENT INTENT.

     It  is  the  Company's  understanding  that  each Company stockholder shall
execute  and  deliver  at  closing or in connection with the exchange procedures
detailed in Section 1.7 hereof a subscription agreement reasonably acceptable to
Parent  evidencing  investment  intent  in  order  to  perfect  a  valid private
placement  under  the  Securities  Act  of  Parent securities issued pursuant to
Section  1.6(a).

     2.22 CLINICAL TRIAL COMPLIANCE.

      Schedule  2.22  of  the  Company  Schedule shall list any and all clinical
trials  that  the  Company  is involved with, in any manner, including the start
date  of the clinical trial, the estimated completion date of the clinical trial
and  the  number  of  patients  currently  involved  in  each  clinical  trial.

     2.23 REPRESENTATIONS AND WARRANTIES CONTINUING.

     The  representations  and  warranties  set  forth  herein shall be true and
correct  on  the  date hereof and subject to an update of the Company's Schedule
from time to time, at all times prior to the Effective Time as if made from time
to  time,  including,  without limitation, at the Closing, except any changes to
the  representations  and  warrants  in Article II due to the termination of the
Company  Warrants or the acceleration and exercise or termination of the Company
Options  as  contemplated  by  Section  4.1.


                                       16

                                   ARTICLE III

             REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB

     Parent  and  Merger  Sub  jointly  and  severally  represent and warrant to
Company,  subject to such exceptions as are specifically disclosed in writing in
the  schedules  hereto  (each  such  exception to reference the specific section
number  of this Article III to which it applies and each other section number of
this  Article III to the extent such applicability is reasonably apparent on the
face  of  such  exception), dated as of the date hereof (the "PARENT SCHEDULE"):

     3.1 ORGANIZATION OF PARENT; SUBSIDIARIES.

     (a)  Parent  and  each of its subsidiaries is a corporation duly organized,
validly  existing and in good standing under the laws of the jurisdiction of its
incorporation;  has  the corporate power and authority to own, lease and operate
its  assets and property and to carry on its business as now being conducted and
as  proposed  to  be conducted; and is duly qualified to do business and in good
standing  as  a foreign corporation in each jurisdiction in which the failure to
be  so  qualified  would  have  a Material Adverse Effect (as defined in Section
8.3(b)(ii))  on  Parent.

     (b)  Schedule  3.1(b)  of  the Parent Schedule contains a true and complete
list  of  all  of  Parent's  subsidiaries,  indicating  the  jurisdiction  of
incorporation  of  each subsidiary and Parent's equity interest therein.  Except
as  set  forth  in  Schedule  3.1(b), neither Parent nor any of its subsidiaries
directly  or  indirectly  owns  an  equity,  membership,  partnership or similar
interest  in,  or  any interest convertible into, or exchangeable or exercisable
for  any  such interest in, any corporation, partnership, joint venture, limited
liability  company  or  other  business  association  or  entity.

     (c)  Parent  has  delivered or made available to Company a true and correct
copy of the Articles of Incorporation and Bylaws of Parent and similar governing
instruments  of  each of its subsidiaries, each as amended     to date, and each
such  instrument  is  in  full  force and effect.  Neither Parent nor any of its
subsidiaries  is  in  violation  of  any  of  the  provisions of its Articles of
Incorporation  or  Bylaws  or  equivalent  governing  instruments.

     (d)  All  of  the  outstanding  shares of capital stock of each of Parent's
subsidiaries  are  duly authorized, validly issued, fully paid and nonassessable
and  are  not  subject  to  preemptive  rights  created  by statute, the charter
documents  of any such subsidiary or any agreement or document to which any such
subsidiary  is  party  or by which its is bound, and all such shares (other than
directors' qualifying shares in the case of applicable foreign subsidiaries) are
owned,  of  record  and  beneficially, by Parent or another subsidiary of Parent
free  and  clear  of all security interests, liens, claims, pledges, agreements,
limitations  on  voting  rights,  charges  or  other encumbrances of any nature.

     3.2  PARENT CAPITAL STRUCTURE.

     The  authorized  capital  stock  of Parent consists of 50,000,000 shares of
common  stock  of  which  7,366,838  shares  are  issued  and  outstanding as of
September  29, 2004 and 10,000,000 shares of preferred stock, of which no shares
are  issued or outstanding.  The authorized capital stock of Merger Sub consists
of  10,000  shares  of  common  stock,  of  which,  1,000  shares are issued and
outstanding  and  held by Parent.  All outstanding shares of Parent Common Stock
are  duly authorized, validly issued, fully paid, and non-assessable and are not
subject  to  preemptive rights created by statute, the Articles of Incorporation
or  Bylaws  of Parent or any agreement or document to which Parent is a party or
by  which  it  is  bound.  As  of  September  29,  2004,  Parent had reserved an
aggregate  of  2,000,000 shares of Parent Common Stock pursuant to the June 2004
compensatory  stock  option  plan  (the "PARENT STOCK OPTION PLAN"), of which no
options  to purchase Parent Common Stock are outstanding.  As of August 31, 2004
Parent  had reserved an aggregate of 1,321,700 shares of Parent Common Stock for
issuance to holders of other options, warrants and rights to purchase or receive
Parent  Common  Stock.  Except  as  set  forth  on  Schedule 3.2 of the Parent's
Schedule, there are no other outstanding obligations or commitments of any kind,
written  or  verbal,  which Parent has agreed to or is otherwise subject to that
would  require  Parent to issue additional shares of Parent Common Stock (or any
other  type of Parent capital stock).  All shares of Parent Common Stock subject
to  issuance


                                       17

as  aforesaid,  upon  issuance  on  the  terms  and  conditions specified in the
instruments  pursuant  to  which  they  are  issuable, would be duly authorized,
validly  issued,  fully  paid,  and  nonassessable.

     3.3  OBLIGATIONS WITH RESPECT TO CAPITAL STOCK.

     Except  as  set  forth  in  Section  3.2, and except as set forth in Parent
Schedule 3.3, as of the date hereof, there are no equity securities, partnership
interests,  or  similar  ownership  interests  of  any  class  of Parent, or any
securities  exchangeable  or  convertible  into  or  exercisable for such equity
securities,  partnership  interests  or  similar  ownership  interests  issued,
reserved  for  issuance  or  outstanding.  Except  for  securities  Parent owns,
directly  or  indirectly  through  one or more subsidiaries, there are no equity
securities, partnership interests or similar ownership interests of any class of
any  subsidiary  of  Parent, or any security exchangeable or convertible into or
exercisable  for  such  equity  securities,  partnership  interests  or  similar
ownership interests issued, reserved for issuance or outstanding.  Except as set
forth  in Section 3.2, and except as set forth in Parent Schedule 3.3, there are
no  stock  appreciation  rights, phantom stock or other similar rights of Parent
and  no  options,  warrants, equity securities, partnership interests or similar
ownership interests, calls, rights (including preemptive rights), commitments or
agreements  of  any  character  to  which Parent or any of its subsidiaries is a
party  or  by  which it is bound obligating Parent or any of its subsidiaries to
issue, deliver or sell, or cause to be issued, delivered or sold, or repurchase,
redeem or otherwise acquire, or cause the repurchase, redemption or acquisition,
of  any  shares  of  capital  stock  of  Parent  or  any  of its subsidiaries or
obligating  Parent  or  any of its subsidiaries to grant, extend, accelerate the
vesting  of  or  enter into any such stock appreciation rights, phantom stock or
other  similar  rights or any such option, warrant, equity security, partnership
interest  or  similar  ownership interest, call, right, commitment or agreement.

     3.4  AUTHORITY.

     (a)  Parent and Merger Sub have all requisite corporate power and authority
to  enter  into  this  Agreement and to consummate the transactions contemplated
hereby.  The  execution  and  delivery of this Agreement and the consummation of
the transactions contemplated hereby, have been duly authorized by all necessary
corporate  action  on  the  part  of  Parent and Merger Sub, subject only to the
filing  and  recordation  of the Certificate of Merger pursuant to Delaware Law.
This  Agreement  has  been  duly executed and delivered by Parent and Merger Sub
and,  assuming  the  due  authorization,  execution  and  delivery  by  Company,
constitutes  the  valid  and  binding  obligations  of  Parent  and  Merger Sub,
enforceable  in  accordance  with  its  terms,  except  as enforceability may be
limited  by  bankruptcy and other similar laws and general principles of equity.
The  execution  and  delivery of this Agreement by Parent and Merger do not, and
the  performance  of  this  Agreement  by  Parent  and  Merger Sub will not, (i)
conflict with or violate the Article of Incorporation or Bylaws of Parent or the
equivalent  organizational documents of any of its subsidiaries, (ii) subject to
compliance  with  the  requirements  set forth in Section 3.4(b) below, conflict
with  or violate any law, rule, regulation, order, judgment or decree applicable
to  Parent or any of its subsidiaries or by which its or any of their respective
properties is bound or affected, or (iii) result in any breach of, or constitute
a  default (or an event that with notice or lapse of time or both would become a
default)  under, or impair Parent's rights or alter the rights or obligations of
any  third  party under, or give to others any rights of termination, amendment,
acceleration  or  cancellation  of,  or  result  in  the  creation  of a lien or
encumbrance  on  any  of  the  properties  or  assets  of  Parent  or any of its
subsidiaries  pursuant  to,  any  note,  bond,  mortgage,  indenture,  contract,
agreement,  lease,  license, permit, franchise or other instrument or obligation
to  which Parent or any of its subsidiaries is a party or by which Parent or any
of  its  subsidiaries  or its or any of their respective properties are bound or
affected,  except  to  the  extent  such  conflict,  violation, breach, default,
impairment  or  other  effect  could  not,  in the case of clause (ii) or (iii),
individually  or  in  the  aggregate,  reasonably be expected to have a Material
Adverse  Effect  on  Parent  or a material adverse effect on Parent's ability to
perform  its  obligations  under  this  Agreement.

     (b)  No  consent,  approval,  order  or  authorization of, or registration,
declaration  or  filing  with  any  Governmental  Entity  is required by or with
respect  to  Parent  in  connection  with  the  execution  and  delivery of this
Agreement  or  the  consummation of the transactions contemplated hereby, except
for  (i)  the filing of the Certificate of Merger with the Secretary of State of
Delaware,  (ii) such consents, approvals, orders, authorizations, registrations,
declarations  and  filings as may be required under applicable federal and state
securities  laws,  and  (iii)  such  other  consents,  authorizations,  filings,
approvals  and  registrations  which,  if  not  obtained  or  made, would not be
material  to  Parent  or  have  a  material adverse effect on the ability of the
parties  to  consummate  the  Merger  or  to  perform the obligations under this
Agreement.


                                       18

     3.5  SEC FILINGS; PARENT FINANCIAL STATEMENTS.

     (a)  Parent has filed all forms, reports and documents required to be filed
with  the  SEC  since  January  1,  2003, and has made available to Company such
forms,  reports and documents in the form filed with the SEC.  All such required
forms,  reports,  and documents (including those that Parent may file subsequent
to  the  date hereof) are referred to herein as the "PARENT SEC REPORTS."  As of
their respective dates, the Parent SEC Reports (i) were prepared in all material
respects  in  accordance  with  the  requirements  of the Securities Act of 1933
("Securities Act") or the Exchange Act of 1933 ("Exchange Act"), as the case may
be,  and  the  rules  and  regulations  of the SEC thereunder applicable to such
Parent  SEC Reports, and (ii) did not at the time they were filed (or if amended
or  superseded by a filing prior to the date of this Agreement, then on the date
of such filing) contain any untrue statement of a material fact or omit to state
a  material fact required to be stated therein or necessary in order to make the
statements  therein,  in  the  light  of the circumstances under which they were
made,  not  misleading.  None  of  Parent's subsidiaries is required to file any
forms,  reports  or  other  documents  with  the  SEC.

     (b)  Each  of  the  consolidated  financial  statements (including, in each
case,  any  related  notes  thereto)  contained  in  the Parent SEC Reports (the
"PARENT  FINANCIALS"),  including  any  Parent  SEC Reports filed after the date
hereof  until the Closing, (i) complied as to form in all material respects with
the  published  rules  and regulations of the SEC with respect thereto, (ii) was
prepared  in  accordance  with GAAP applied on a consistent basis throughout the
periods  involved  (except  as  may be indicated in the notes thereto or, in the
case  of  unaudited interim financial statements, as may be permitted by the SEC
on  Form  10-QSB  under  the  Exchange  Act)  and  (iii)  fairly  presented  the
consolidated financial position of Parent and its subsidiaries at the respective
dates  thereof and the consolidated results of its operations and cash flows for
the  periods  indicated,  except that the unaudited interim financial statements
were or are subject to normal and recurring year-end adjustments which were not,
or  are  not  expected  to  be,  material in amount. The balance sheet of Parent
contained  in the Parent SEC Reports as of June 30, 2004 is hereinafter referred
to as the "PARENT BALANCE SHEET."  Except as disclosed in the Parent Financials,
neither  Parent  nor  any  of  its  subsidiaries  has any liabilities (absolute,
accrued,  contingent  or  otherwise)  of  a nature required to be disclosed on a
balance  sheet  or in the related notes to the consolidated financial statements
prepared  in  accordance  with GAAP which are, individually or in the aggregate,
material to the business, results of operations or financial condition of Parent
and  its  subsidiaries  taken as a whole, except liabilities (i) provided for in
the  Parent Balance Sheet, or (ii) incurred since the date of the Parent Balance
Sheet  in  the  ordinary  course  of  business  and immaterial in the aggregate.

     3.6  ABSENCE OF CERTAIN CHANGES OR EVENTS.

     Since  the  date  of  the Parent Balance Sheet, there has not been: (i) any
Material  Adverse  Effect  on  the  Parent,  (ii)  any  split,  combination,  or
reclassification  of  any of Parent's or any of its subsidiaries' capital stock,
(iii)  any  material  change  by Parent in its accounting methods, principles or
practices,  except  as  required  by  concurrent  changes  in  GAAP,  (iv)  any
revaluation  by  Parent  of  any  of  its assets, including, without limitation,
writing down the value of capitalized inventory or writing off notes or accounts
receivable  other  than  in the ordinary course of business and consistent  with
past  practice.

     3.7  TAXES.

     (a)  Parent  and  each  of  its  subsidiaries have timely filed all Returns
and/or  extensions  relating to Taxes required to be filed by Parent and each of
its  subsidiaries  with any Tax authority, except such Returns which are     not
material  to  Parent.  Parent  and  each of its subsidiaries have paid all Taxes
shown  to  be  due  on  such  Returns.

     (b)  Parent and each of its subsidiaries as of the Effective Time will have
withheld with respect to its employees all federal and state income Taxes, Taxes
pursuant  to  the  Federal  Unemployment  Tax Act and other Taxes required to be
withheld,  except  such  Taxes  which  are  not  material  to  Parent.

     (c)  Neither  Parent nor any of its subsidiaries has been delinquent in the
payment  of  any  material  Tax  nor  is  there  any  material  Tax  deficiency
outstanding, proposed or assessed against Parent or any of its subsidiaries, nor
has  Parent  or  any  of  its  subsidiaries executed any unexpired waiver of any
statute  of  limitations  on  or  extending  the  period  for  the assessment or
collection  of  any  Tax.


                                       19

     (d)  No  audit  or  other examination of any Return of Parent or any of its
subsidiaries  by  any  Tax authority is presently in progress, nor has Parent or
any  of its subsidiaries been notified of any request for such an audit or other
examination.

     (e)  No  adjustment  relating  to any Returns filed by Parent or any of its
subsidiaries  has  been  proposed  in  writing formally or informally by any Tax
authority  to  Parent,  any  of  its subsidiaries or any representative thereof.

     (f)  Neither  Parent  nor any of its subsidiaries has any liability for any
material  unpaid  Taxes  which  has  not been accrued for or reserved on Company
Balance  Sheet  in  accordance  with  GAAP,  whether  asserted  or  unasserted,
contingent  or  otherwise.

     3.8  PARENT INTELLECTUAL PROPERTY.

     For  the purposes of this Agreement, the following terms have the following
definitions:

     "PARENT INTELLECTUAL PROPERTY" shall mean any Intellectual Property that is
owned  by,  or  exclusively  licensed  to,  Parent  or  any of its subsidiaries,
including  but  not  limited,  to  the  license agreement with the University of
Chicago  dated  February  20,  2004,  copies of which have been delivered to the
Company.

     (a)  No Parent Intellectual Property or product or service of Parent or any
of  its  subsidiaries is subject to any proceeding or outstanding decree, order,
judgment, contract, license, agreement, or stipulation restricting in any manner
the use, transfer, or licensing thereof by Parent or any of its subsidiaries, or
which may affect the validity, use or enforceability of such Parent Intellectual
Property.

     (b)  To  the  knowledge  of  Parent,  Parent  owns, or has license or other
rights  to  use  (sufficient  for  the  conduct  of  its  business  as currently
conducted),  each  material  item  of  Parent  Intellectual  Property  or  other
Intellectual  Property  used by Parent free and clear of any lien or encumbrance
(excluding  licenses  and  related  restrictions).

     (c)  Neither  Parent  nor any of its subsidiaries has transferred ownership
of,  or  granted  any  license  with respect to any material Parent Intellectual
Property  to  any  third  party.

     (d)  To  the  knowledge  of Parent, the operation of the business of Parent
and  its  subsidiaries as such business currently is conducted does not infringe
the  Intellectual  Property  of  any  third  party.

     (e)  Neither  Parent  nor  any of its subsidiaries has received notice from
any  third  party  that  the  operation  of the business of Parent or any of its
subsidiaries  or  any  act,  product  or  service  of  Parent  or  any  of  its
subsidiaries,  infringes  the  Intellectual  Property  of  any  third  party.

     (f)  To  the  knowledge  of  Parent,  no  person  has  or  is infringing or
misappropriating  any  material  Parent  Intellectual  Property.

     3.9  COMPLIANCE; PERMITS; RESTRICTIONS.

     (a)  Neither  Parent  nor  any  of  its  subsidiaries  is,  in any material
respect,  in  conflict  with,  or  in default or violation of (i) any law, rule,
regulation,  order,  judgment  or  decree  applicable  to  Parent  or any of its
subsidiaries  or  by which its or any of their respective properties is bound or
affected,  or  (ii)  any  material  note,  bond,  mortgage, indenture, contract,
agreement,  lease,  license, permit, franchise or other instrument or obligation
to  which Parent or any of its subsidiaries is a party or by which Parent or any
of  its  subsidiaries  or  its or any of their respective properties is bound or
affected.  To  the  knowledge  of Parent, no formal or informal investigation or
review  by  any  Governmental  Entity,  including  the  Securities  and Exchange
Commission ("SEC"), is pending or threatened against Parent or its subsidiaries.
In addition, Parent has not received any inquiry letters or other correspondence
from  the  SEC  relating  to  any  pending  inquiries, investigations or similar
matters.  There  is no material agreement, judgment, injunction, order or decree
binding  upon Parent or any of its subsidiaries which has or could reasonably be
expected  to  have the effect of prohibiting or materially impairing any current
business  practice  of  Parent  or  any  of  its


                                       20

subsidiaries,  any  acquisition  of  material  property  by Parent or any of its
subsidiaries  or  the  conduct  of  business  by  Parent as currently conducted.

     (b)  Parent  and  its  subsidiaries  hold all permits, licenses, variances,
exemptions,  orders  and  approvals  from  governmental  authorities  which  are
material  to  the operation of the business of Parent (collectively, the "PARENT
PERMITS").  Parent  and  its  subsidiaries  are  in  compliance  in all material
respects  with  the  terms  of  the  Parent  Permits.

     3.10 LITIGATION.

     As  of  the date of this Agreement, excluding such matters as are disclosed
in  Parent's  SEC  Reports,  there  is  no  action,  suit,  proceeding,  claim,
arbitration  or  investigation  pending,  or  as  to  which Parent or any of its
subsidiaries has received any notice of assertion nor, to Parent's knowledge, is
there a threatened action, suit, proceeding, claim, arbitration or investigation
against Parent or any of its subsidiaries which reasonably would be likely to be
material  to  Parent,  or  which  in  any manner challenges or seeks to prevent,
enjoin,  alter  or delay any of the transactions contemplated by this Agreement.

     3.11 BROKERS' AND FINDERS' FEES.

     Except  for  Parent's  obligation  to Sanders Morris Harris, Parent has not
incurred, nor will it incur, directly or indirectly, any liability for brokerage
or  finders'  fees  or  agents' commissions or any similar charges in connection
with  this  Agreement  or  any  transaction  contemplated  hereby.

     3.12 ENVIRONMENTAL MATTERS.

     (a)  Except  as  would  not  reasonably  be  likely to result in a Material
Adverse  Effect  on  Parent,  (i) neither Parent nor any of its subsidiaries has
generated,  transported,  stored,  used,  manufactured, disposed of, released or
exposed  its  employees  or  others  to pollutants, contaminants, wastes, or any
toxic,  radioactive  or otherwise hazardous materials ("HAZARDOUS MATERIALS") in
violation  of,  or  in  a  manner  that  would be reasonably likely to result in
liability  under,  any  rule,  regulation,  treaty or statute promulgated by any
Governmental  Entity  in effect as of the date hereof to protect the environment
or  to  prohibit, regulate or control Hazardous Materials ("ENVIRONMENTAL LAWS")
and  (ii)  no Hazardous  Materials are located in, on or under any real property
or  facility now or previously owned, leased or operated by Parent or any of its
subsidiaries  in  a  manner  which  would  reasonably  be  expected to result in
liability  under,  or  a  violation  of,  any  Environmental  Law.

     (b)  Except for matters which would not reasonably be expected to result in
a  Material  Adverse  Effect  on  Company,  no  action,  proceeding,  revocation
proceeding,  amendment  procedure,  writ,  injunction or claim is pending, or to
Parent's  knowledge,  threatened  concerning  any Company Permit relating to any
environmental  matter,  or  otherwise  relating  to  any  Environmental  Law.

     3.13 LABOR MATTERS.

     (i)  There  are  no  controversies  pending or, to the knowledge of each of
Parent and its respective subsidiaries, threatened, between Parent or any of its
subsidiaries  and any of their respective employees or independent contributors;
(ii)  as  of  the  date  of  this  Agreement,  neither  Parent  nor  any  of its
subsidiaries  is  a  party to any collective bargaining agreement or other labor
union  contract applicable to persons employed by Parent or its subsidiaries nor
does  Parent  or  its  subsidiaries know of any activities or proceedings of any
labor  union  to  organize  any such employees; and (iii) as of the date of this
Agreement,  neither  Parent nor any of its subsidiaries has any knowledge of any
strikes,  slowdowns,  work stoppages or lockouts, or threats thereof, by or with
respect  to  any  employees  of  Parent  or  any  of  its  subsidiaries.

     3.14 MATERIAL AGREEMENTS.

     Since the date of the most recently filed Parent SEC Report, Parent has not
entered  into any material agreement, compensatory agreement or adopted any plan
that  would  be required to be filed by Parent with the SEC, except as set forth
on  Schedule  3.14  of  the  Parent  Schedules.


                                       21

     3.15 CASH AND CASH EQUIVALENTS.

     As  of  October  1, 2004, Parent has cash and cash equivalents in excess of
one  million  dollars  ($1,000,000).

                                   ARTICLE IV

                       CONDUCT PRIOR TO THE EFFECTIVE TIME

     4.1  CONDUCT OF BUSINESS BY COMPANY.

     During  the period from the date of this Agreement and continuing until the
earlier  of  the  termination  of  this  Agreement  pursuant to its terms or the
Effective Time, Company and each of its subsidiaries shall, except to the extent
that  Parent  shall  otherwise consent in writing, carry on its business, in the
ordinary course, in substantially the same manner as heretofore conducted and in
compliance  with  all  applicable laws and regulations, and use its commercially
reasonable  efforts  consistent with past practices and policies to (i) preserve
intact its present business organization as set forth in the Opexa Business Plan
March 2004, as previously provided to Parent and Merger Sub, (ii) keep available
the  services  of  its  present  officers  and employees, and (iii) preserve its
relationships with customers, suppliers, distributors, licensors, licensees, and
others  with which it has business dealings. Additionally, Company shall provide
Parent's management access to meet with employees for the purposes of discussing
continued  employment.  Notwithstanding  anything  in  this  Section  4.1 to the
contrary,  Parent hereby acknowledges and agrees that the Company shall (i) have
the  right to accelerate the Company Options, (ii) if needed, forgiveness of the
options  exercise  price,  but  not  to exceed $105,000, and (iii) terminate the
Company  Warrants.

     In  addition,  except as expressly permitted by the terms of this Agreement
and  except  as  set  forth in Schedule 4.1 without the prior written consent of
Parent,  during  the period from the date of this Agreement and continuing until
the  earlier  of  the termination of this Agreement pursuant to its terms or the
Effective  Time,  Company shall not do any of the following and shall not permit
its  subsidiaries  to  do  any  of  the  following:

     (a)  Waive  any  stock  repurchase  rights, accelerate, amend or change the
period  of exercisability of warrants or options or restricted stock, or reprice
Company  Warrants  or  Company  Options  granted under any employee, consultant,
director  or  other  stock  plans or authorize cash payments in exchange for any
options  granted  under  any  of  such  plans;

     (b)  Grant  any  severance  or  termination  pay to any officer or employee
except  pursuant to written agreements outstanding, or policies existing, on the
date  hereof  and as previously disclosed in writing, or adopt any new severance
plan;

     (c)  Transfer or license to any person or entity or otherwise extend, amend
or  modify  any  rights  to  the  Company  Intellectual  Property;

     (d)  Declare,  set  aside  or  pay  any  dividends  on  or  make  any other
distributions (whether in cash, stock, equity securities or property) in respect
of any capital stock, or split, combine or reclassify any capital stock or issue
or  authorize  the issuance of any other securities in respect of, in lieu of or
in  substitution  for  any  capital  stock;

     (e)  Purchase,  redeem  or  otherwise  acquire, directly or indirectly, any
shares  of  capital  stock  of  Company  or  its  subsidiaries;

     (f)  Issue,  deliver,  sell,  authorize,  pledge  or otherwise encumber any
shares  of  capital  stock  or any securities convertible into shares of capital
stock,  or  subscriptions,  rights, warrants or options to acquire any shares of
capital  stock  or  any  securities convertible into shares of capital stock, or
enter  into  other  agreements  or commitments of any character obligating it to
issue  any  such  shares  or  convertible  securities,  other than the issuance,
delivery and/or sale of Company Common Stock pursuant to the exercise of Company
Options  and  Company  Warrants  outstanding  as  of the date of this Agreement;


                                       22

     (g)  Cause,  permit  or  propose  any  amendments  to  the  Company charter
documents,  other than the amendment of the Series A Preferred Stock designation
as  contemplated  in  Section  6.3  of  the  Agreement  (or  similar  governing
instruments  of  any  of  its  subsidiaries);

     (h)  Acquire  or  agree  to acquire by merging or consolidating with, or by
purchasing  any  equity interest in or portion of the assets of, or by any other
manner,  any  business  or  any  corporation,  partnership, association or other
business  organization  or  division  thereof,  or otherwise acquire or agree to
acquire  any  assets,  strategic  partnerships  or  alliances;

     (i)  Sell,  lease,  license,  pledge,  encumber or otherwise dispose of any
properties  or  assets;

     (j)  Incur  any  indebtedness  for  borrowed  money  or  guarantee any such
indebtedness  of  another  person, issue or sell any debt securities or options,
warrants, calls or other rights to acquire any debt securities of Company, enter
into  any  agreement to maintain any financial statement condition or enter into
any arrangement having the economic effect of any of the foregoing other than in
connection  with the financing of ordinary course trade payables consistent with
past  practice (other than as contemplated in Section 5.10 hereof) except in the
ordinary course of business consistent with past practice or as otherwise deemed
necessary by the Board of Directors to maintain the Company's current operations
and  the  written  consent  of  Parent;

     (k)  Adopt  or  amend any employee benefit plan, policy or arrangement, any
employee  stock  purchase  or  employee  stock  option  plan,  or enter into any
employment  contract  or  collective  bargaining  agreement,  hire,  terminate,
re-title,  reclassify,  promote,  demote,  or any manner alter the status of any
current  employee, pay any special bonus or special remuneration to any director
or  employee,  or  increase  the  salaries  or  wage  rates  or  fringe benefits
(including  rights to severance or  indemnification) of its directors, officers,
employees  or  consultants;

     (l)  (i) Pay, discharge, settle or satisfy any material claims, liabilities
or  obligations  (absolute,  accrued,  asserted  or  unasserted,  contingent  or
otherwise),  or  litigation  (whether or not commenced prior to the date of this
Agreement) in which Company is a defendant, or (ii) waive the benefits of, agree
to  modify  in any manner, terminate, release any person from or fail to enforce
any confidentiality or similar agreement to which Company is a party or of which
Company  is  a  beneficiary;

     (m)  Modify, amend or terminate any material contract or agreement to which
Company  thereof  is  a party or waive, delay the exercise of, release or assign
any  material rights or claims thereunder without the written consent of Parent;

     (n)  Incur and enter into any agreement, contract or commitment which if in
existence  on the date hereof would be required to be listed in Company Schedule
2.17  except in the ordinary course of business consistent with past practice to
maintain  the  Company's  current  operations;

     (o)  Revalue  any  of  its  assets or, except as required by GAAP, make any
change  in  accounting  methods,  principles  or  practices;

     (p)  Engage  in  any  action that would reasonably be expected to cause the
Merger  to  fail  to  qualify  as a "reorganization" under Section 368(a) of the
Code,  whether  or not otherwise permitted by the provisions of this     Article
IV;

     (q)  Make  any  Tax  election  that,  individually  or in the aggregate, is
reasonably  likely to adversely affect in any material respect the Tax liability
or  Tax attributes of  Company or Parent or any of its subsidiaries or settle or
compromise  any  material  income  Tax  liability;

     (r)  Make  any disbursements or payments, other than in the ordinary course
of  business  to  maintain  the  Company's  current  operations;

     (s)  Engage  in  any  conduct, solicited or otherwise, relating to business
development,  business combination, financing, disposition of assets, licensing,
joint  venture  or  other  related  discussions  on  behalf  of  the


                                       23

Company with any third parties, other than in the ordinary course of business or
as  otherwise  deemed  necessary  by  the  Board  of  Directors  to maintain the
Company's  current  operations  with  the  written  consent  of  Parent;

     (t)  Engage  in  any  conduct  in  breach  of  Section  5.3  or 5.4 of this
Agreement;  or

     (u)  Agree  in writing or otherwise to take any of the actions described in
Sections  4.1  (a)  through  (t)  above.

     4.2  CONDUCT OF BUSINESS BY PARENT.

     During  the period from the date of this Agreement and continuing until the
earlier  of  the  termination  of  this  Agreement  pursuant to its terms or the
Effective  Time, Parent and each of its subsidiaries shall, except to the extent
that  Company  shall otherwise consent in writing, carry on its business, in the
ordinary course, in substantially the same manner as heretofore conducted and in
compliance  with  all  applicable  laws and regulations, pay its debts and taxes
when due subject to good faith disputes over such debts or taxes, pay or perform
other material obligations when due, and use its commercially reasonable efforts
consistent  with  past practices and policies to (i) preserve intact its present
business  organization, (ii) keep available the services of its present officers
and  employees  and  (iii) preserve its relationships with customers, suppliers,
distributors,  licensors,  licensees,  and  others  with  which  it has business
dealings.

     In  addition, except as expressly permitted by the terms of this Agreement,
without the prior written consent of Company, during the period from the date of
this  Agreement  and  continuing  until  the  earlier of the termination of this
Agreement  pursuant  to its terms or the Effective Time, Parent shall not do any
of  the  following  and  shall  not  permit  its  subsidiaries  to do any of the
following:

     (a)  Waive  any  stock  repurchase  rights, accelerate, amend or change the
period  of exercisability of warrants or options or restricted stock, or reprice
warrants  or  options  granted under any employee, consultant, director or other
stock plans or authorize cash payments in exchange for any options granted under
any  of  such  plans;

     (b)  Declare,  set  aside  or  pay  any  dividends  on  or  make  any other
distributions (whether in cash, stock, equity securities or property) in respect
of  any  capital  stock,  except for intercompany dividends or distributions, or
split,  combine  or  reclassify  any  capital  stock  or  issue or authorize the
issuance  of  any  other securities in respect of, in lieu of or in substitution
for  any  capital  stock,  except  as  set  forth  in  Parent  Schedules;

     (c)  Cause,  permit  or  propose  any  amendments  to  the  Parent  charter
documents  (or  similar  governing  instruments of any of its subsidiaries) that
would  have  an  adverse effect on the rights of holders of Parent Common Stock;

     (d)  Revalue  any  of  its  assets or, except as required by GAAP, make any
change  in  accounting  methods,  principles  or  practices;

     (e)  Engage  in  any  action that would reasonably be expected to cause the
Merger  to  fail  to  qualify  as a "reorganization" under Section 368(a) of the
Code,  whether  or not otherwise permitted by the provisions of this Article IV;

     (f)  Make  any  Tax  election  that,  individually  or in the aggregate, is
reasonably  likely to adversely affect in any material respect the Tax liability
or  Tax  attributes of Parent or any of its subsidiaries or settle or compromise
any  material  income  Tax  liability;  or

     (g)  Agree  in writing or otherwise to take any of the actions described in
Sections  4.2  (a)  through  (f)  above.


                                       24

                                    ARTICLE V

                              ADDITIONAL AGREEMENTS

     5.1  DOCUMENTATION  TO BE DISTRIBUTED TO COMPANY SHAREHOLDERS AND NOTICE TO
PREFERRED  STOCK  HOLDERS.

     The  Company  shall  prepare  documentation  acceptable  to  Parent  to  be
disseminated  to  Company  shareholders to consider in voting at the Shareholder
Meeting  as described in Section 5.2 below.  The Company shall provide notice to
the  Company  Preferred  Stock  holders  in  accordance  with the certificate of
designation.

     5.2  SHAREHOLDER MEETING.

     Company  shall  call and hold the Company Shareholders' Meeting as promptly
as practicable after the date hereof, but no later than October 25, 2004, or the
Company  shall  solicit  the  written consent of its stockholders as promptly as
practicable  after  the date hereof, for the purpose of voting upon the adoption
and  approval  of  this  Agreement,  the approval of the Merger, and approval of
other  matters  requiring  shareholder  vote.  Unless  the  Company's  Board  of
Directors  has  withdrawn its recommendation of this Agreement and the Merger in
compliance  with  Section 5.4, Company shall use commercially reasonable efforts
to  solicit  from its shareholders proxies in favor of the adoption and approval
of  this  Agreement  and  the  approval  of  the Merger and shall take all other
commercially  reasonable  action  necessary  or  advisable to secure the vote or
consent  of  stockholders  required  by  Delaware  Law  to obtain such approval.

     5.3  CONFIDENTIALITY; ACCESS TO INFORMATION.

     (a)  The  parties  acknowledge  that  Company  and  Parent  have previously
executed  a  Confidentiality  Agreement,  dated  as  of  June  15,  2004  (the
"CONFIDENTIALITY  AGREEMENT"),  which Confidentiality Agreement will continue in
full  force  and  effect  in  accordance  with  its  terms.

     (b)  Each  of  Company  and  Parent  will  afford the other and the other's
accountants,  counsel  and  other  representatives  reasonable  access  to  its
properties,  books,  records,  shareholder  lists  and  personnel  during  the
period  prior  to  the  Effective  Time to obtain all information concerning its
business  as  such  other  party  may  reasonably  request.  No  information  or
knowledge obtained in any investigation pursuant to this Section 5.3 will affect
or  be  deemed  to modify any representation or warranty contained herein or the
conditions  to  the  obligations  of  the  parties  to  consummate  the  Merger.

     5.4  NO SOLICITATION.

     From  and  after  the  date  of  this Agreement until the Effective Time or
termination  of  this  Agreement  pursuant  to  Article  VII,  Company  and  its
subsidiaries will not, nor will they authorize or permit any of their respective
officers,  directors, affiliates or employees or any investment banker, attorney
or  other  advisor  or  representative  retained  by any of them to, directly or
indirectly, (A) solicit, initiate, encourage or induce the making, submission or
announcement  of  any  Acquisition  Proposal  (as  defined  below)  including
communicating  with,  responding  to, or receiving communications from any party
regarding  financing or strategic transactions or communicating to any financing
or  strategic  counterparties  the  nature  or  extent  of  this  Agreement, (B)
participate  in  any  discussions  or  negotiations regarding, or furnish to any
person  any  information  with respect to, or knowingly take any other action to
facilitate  any  inquiries or the making of any proposal that constitutes or may
reasonably be expected to lead to, any Acquisition Proposal, including divulging
any information with respect to the transaction set forth in this Agreement, (C)
engage  in discussions with any person with respect to any Acquisition Proposal,
(D) approve, endorse or recommend any Acquisition Proposal or (D) enter into any
letter  of  intent  or similar document or any contract, agreement or commitment
contemplating  or  otherwise relating to any Acquisition Transaction (as defined
below);  provided,  however,  that  nothing  contained in this Section 5.4 shall
prohibit  the Board of Directors of Company from responding at any time prior to
the  Company  Shareholder  Meeting,  to a bona fide written Acquisition Proposal
received  without  the  prior  occurrence  of  a breach of this Section 5.4 that
Company's  Board  of  Directors  reasonably  concludes  constitutes  a  Superior
Proposal  (as  defined  below),  engaging  in  discussions  or  participating in
negotiations  with  and  furnishing  information  to  the  party  making  such
Acquisition  Proposal  to  the


                                       25

extent  (1)  the  Board  of  Directors of Company determines in good faith after
consultation with its outside legal counsel that its fiduciary obligations under
applicable  law require it to do so, (2) (x) at least two business days prior to
furnishing  any  such  nonpublic information to, or entering into discussions or
negotiations  with, such party, Company gives Parent written notice of Company's
intention  to  furnish  nonpublic  information  to, or enter into discussions or
negotiations  with,  such  party  and  (y)  Company  receives from such party an
executed  confidentiality  agreement containing customary limitations on the use
and  disclosure  of all nonpublic written and oral information furnished to such
party  by or on behalf of Company, and (3) contemporaneously with furnishing any
such  nonpublic  information  to  such  party,  Company furnishes such nonpublic
information  to  Parent  (to  the extent such nonpublic information has not been
previously  furnished  by  Company to Parent). Company and its subsidiaries will
immediately  cease any and all existing activities, discussions, or negotiations
with  any parties conducted heretofore with respect to any Acquisition Proposal.
Without  limiting  the  foregoing,  it  is  understood that any violation of the
restrictions  set  forth in this Section 5.4 by any officer, director, affiliate
or  employee  of  Company  or  any of its subsidiaries or any investment banker,
attorney  or  other  advisor  or  representative  of  Company  or  any  of  its
subsidiaries shall be deemed to be a breach of this Section 5.4 by Company.  For
purposes  of  this  Agreement,  (A) "ACQUISITION PROPOSAL" shall mean any offer,
inquiry  or  proposal  (other  than  an  offer,  inquiry  or proposal by Parent)
relating  to  any  Acquisition  Transaction; (B) "ACQUISITION TRANSACTION" shall
mean  any  transaction  or  series  of  related  transactions  other  than  the
transactions  contemplated  by  this Agreement involving: (X) any acquisition or
purchase  from  Company by any person or "group" (as defined under Section 13(d)
of  the  Exchange  Act  and the rules and regulations thereunder) or any merger,
consolidation, business combination or similar transaction involving the Company
and  its  shareholders;  (Y)  any  sale,  lease,  exchange,  transfer,  license,
acquisition  or  disposition  of  any assets of Company; or (Z) any liquidation,
dissolution,  recapitalization  or other significant corporate reorganization of
the Company; and (C) "SUPERIOR PROPOSAL" shall mean an Acquisition Proposal with
respect to which (x) if any cash consideration is involved, shall not be subject
to  any  financing  contingency  or  with  respect  to  which Company's Board of
Directors  shall  have reasonably determined (based upon the advice of Company's
financial  advisors)  that  the  acquiring  party is capable of consummating the
proposed  Acquisition Transaction on the terms proposed, and (y) Company's Board
of  Directors  shall  have  reasonably  determined that the proposed Acquisition
Transaction  provides  greater  value  to  the  shareholders of Company than the
Merger  (based  upon  a  written  opinion  of  Company's financial advisor).  In
addition to the obligations of Company set forth in this Section 5.4, Company as
promptly  as  practicable, and in any event within 24 hours, shall advise Parent
orally  and  in  writing of any request for information which Company reasonably
believes  would  lead  to an Acquisition Proposal or of any Acquisition Proposal
(whether  solicited  or  unsolicited),  or  any inquiry with respect to or which
Company  reasonably  believes  would  lead  to any Acquisition Proposal (whether
solicited  or  unsolicited),  the material terms and conditions of such request,
Acquisition  Proposal or inquiry, and the identity of the person or group making
any  such request, Acquisition Proposal or inquiry. Company will not communicate
with  any  third party (whether solicited or unsolicited) without the consent of
Parent, and will keep Parent informed in all material respects of the status and
details  (including  material  amendments  or  proposed  amendments) of any such
request,  Acquisition  Proposal,  or  inquiry.  In  addition  to  the foregoing,
Company  shall  (A)  provide Parent with at least 48 hours prior notice (or such
lesser  prior  notice as provided to the members of Company's Board of Directors
but  in  no  event  less  than eight hours) of any meeting of Company's Board of
Directors  at  which  Company's  Board  of  Directors  is reasonably expected to
consider  an Acquisition Proposal and (B) provide Parent with at least three (3)
business  days prior written notice of a meeting of Company's Board of Directors
at  which  Company's  Board  of  Directors is reasonably expected to recommend a
Superior  Proposal  to  its shareholders and together with such notice a copy of
the  definitive  documentation relating to such Superior Proposal.  The Board of
Directors of the Company shall not (a) withdraw or modify in a manner adverse to
Parent,  the  approval  or  recommendation  by  such  Board of Directors of this
Agreement,  or  (b)  approve  or  recommend any Acquisition Proposal, unless the
Company  receives  an  Acquisition  Proposal  and  the Board of Directors of the
Company  determines  in  good faith that such Acquisition Proposal is a Superior
Proposal.

     5.5  PUBLIC DISCLOSURE.

     Parent  and  Company  will consult with each other and agree before issuing
any  press  release or otherwise making any public statement with respect to the
Merger,  this  Agreement  or an Acquisition Proposal and will not issue any such
press  release or make any such public statement prior to such agreement, except
as  may  be required by Parent to comply with federal and state securities laws.


                                       26

     5.6  REASONABLE EFFORTS; NOTIFICATION.

     (a)  Upon  the  terms  and  subject  to  the  conditions  set forth in this
Agreement,  each of the parties agrees to use commercially reasonable efforts to
take,  or cause to be taken, all actions, and to do, or cause to be done, and to
assist  and  cooperate  with  the  other parties in doing, all things necessary,
proper  or  advisable  to consummate and make effective, in the most expeditious
manner  practicable,  the Merger and the other transactions contemplated by this
Agreement,  including  using  commercially  reasonable efforts to accomplish the
following:  (i)  the  taking  of  all     reasonable acts necessary to cause the
conditions precedent set forth in Article VI to be satisfied, (ii) the obtaining
of all necessary actions or nonactions, waivers, consents, approvals, orders and
applicable  authorizations from Governmental Entities, if any, and the making of
all  necessary  registrations,  declarations  and  filings and the taking of all
reasonable  steps  as  may  be  necessary  to  avoid  any  suit,  claim, action,
investigation  or  proceeding by any Governmental Entity, (iii) the obtaining of
all  necessary  consents,  approvals  or  waivers  from  third parties, (iv) the
defending  of any suits, claims, actions, investigations or proceedings, whether
judicial  or  administrative,  challenging this Agreement or the consummation of
the  transactions  contemplated  hereby,  including  seeking to have any stay or
temporary  restraining  order  entered by any court or other Governmental Entity
vacated  or  reversed  and  (v)  the  execution  or  delivery  of any additional
instruments  necessary  to  consummate  the transactions contemplated by, and to
fully  carry out the purposes of, this Agreement. In connection with and without
limiting  the  foregoing, Company and its Board of Directors shall, if any state
takeover  statute  or  similar statute or regulation is or becomes applicable to
the  Merger,  this  Agreement,  the  Company  Voting  Agreements  or  any of the
transactions  contemplated  hereby  and  thereby,  use  commercially  reasonable
efforts to ensure that the Merger, this Agreement, the Company Voting Agreements
and the other transactions contemplated hereby and thereby may be consummated as
promptly  as  practicable  on  the  terms  contemplated  by  this  Agreement and
otherwise  to  minimize  the effect of such statute or regulation on the Merger,
this  Agreement, the Company Voting Agreements and the transactions contemplated
hereby  and thereby. Notwithstanding anything herein to the contrary, nothing in
this Agreement shall be deemed to require Parent or Company or any subsidiary or
affiliate thereof to agree to any divestiture by itself or any of its affiliates
of  shares  of  capital  stock  or  of  any business, assets or property, or the
imposition  of  any material limitation on the ability of any of them to conduct
their  business  or  to  own  or exercise control of such assets, properties and
stock.

     (b)  Company  shall  give  prompt notice to Parent of any representation or
warranty  made  by it contained in this Agreement becoming untrue or inaccurate,
or  any failure of Company to comply with or satisfy in any material respect any
covenant,  condition  or  agreement to be complied with or satisfied by it under
this  Agreement, in each case, such that the conditions set forth in Section 6.3
would  not  be  satisfied;  provided,  however,  that no such notification shall
affect  the  representations, warranties, covenants or agreements of the parties
or  the  conditions  to  the  obligations  of  the parties under this Agreement.

     (c)  Parent  shall  give  prompt notice to Company of any representation or
warranty made by it or Merger Sub contained in this Agreement becoming untrue or
inaccurate,  or any failure of Parent or Merger Sub to comply with or satisfy in
any material respect any covenant, condition or agreement to be complied with or
satisfied by it under this Agreement, in each case, such that the conditions set
forth  in  Section  6.2  would not be satisfied; provided, however, that no such
notification  shall  affect  the  representations,  warranties,  covenants  or
agreements  of  the  parties or the conditions to the obligations of the parties
under  this  Agreement.

     5.7  THIRD- PARTY CONSENTS.

     As  soon  as practicable following the date hereof, Parent and Company will
each  use  commercially  reasonable  efforts to obtain any consents, waivers and
approvals  under  any  of  its  or  its  subsidiaries'  respective  agreements,
contracts,  licenses  or  leases  required to be obtained in connection with the
consummation  of  the  transactions  contemplated  hereby.

     5.8  LISTING OF PARENT COMMON STOCK.

     Parent shall use its best efforts to list the Parent Common Stock issued in
exchange  for the Company Preferred Stock and Company Common Stock on the Nasdaq
Stock Market or The American Stock Exchange as soon as practicable following the
Effective  Date.  In the event that Parent is not eligible for listing on either
of  the


                                       27

markets above, Parent shall use its best efforts to bring Parent into compliance
with  the  initial  listing  requirements  of  one  of  such  markets as soon as
practicable  following  the  Effective  Date.

     5.9  ELECTION OF TWO DIRECTORS.

     As  soon as practicable following the Effective Time, Parent shall cause to
have  nominated  for  election,  and  shall  use  its  best  efforts to have its
shareholders  elect,  up  to  (2) two nominees agreed upon by the Company and in
accordance  with  the  License  Agreement,  at  least  one  (1) of whom shall be
"independent"  as  defined  in  the Securities Act of 1933, as amended, provided
that,  Parent shall only be obligated to nominate such nominees if such nominees
are  otherwise  qualified  and  are  willing  to  serve  as  directors.

     5.10  PARENT LOAN TO COMPANY.

     Parent  agrees to loan the Company up to $200,000 on the date hereof, to be
used exclusively for the expenses and costs as set forth on Schedule 5.10 of the
Company  Schedule  ("Allowable Expenses")  Schedule 5.10 of the Company Schedule
shall  include  a  line  item for each Allowable Expense including the estimated
amount  of the Allowable Expense for the month of October 2004.  Such loan shall
mature  on  the  earlier of Closing or Termination (as defined in Article VII of
this  Agreement),  shall  bear interest at a rate of ten percent (10%) per annum
and  shall  be  secured  by  all  the  Company's assets, except its Intellectual
Property.   Such  loan shall be in form of Exhibit D, attached hereto and made a
part  hereof.


                                   ARTICLE VI

                            CONDITIONS TO THE MERGER

     6.1  CONDITIONS  TO  OBLIGATIONS  OF  EACH  PARTY  TO  EFFECT  THE  MERGER.

     The  respective  obligations  of each party to this Agreement to effect the
Merger shall be subject to the satisfaction at or prior to the Effective Time of
the  following  conditions:

     (a)  Stockholder  Approval.  This  Agreement  shall  have been approved and
          ----------------------
adopted,  and  the  Merger  shall have been duly approved, by the requisite vote
under  applicable law, by the shareholders of Company on or prior to October 31,
2004.

     (b)  No  Order.  No  Governmental  Entity  shall  have  enacted,  issued,
          ----------
promulgated, enforced or entered any statute, rule, regulation, executive order,
decree,  injunction or other order (whether temporary, preliminary or permanent)
which  is  in  effect  and  which has the effect of making the Merger illegal or
otherwise  prohibiting  consummation  of  the  Merger.

     (c)  Financing.  The  Parent  shall  have  raised  three  million  dollars
          ---------
($3,000,000)  through  the  issuance  of  convertible  notes since July 1, 2004.

     6.2  ADDITIONAL CONDITIONS TO OBLIGATIONS OF COMPANY.

     The  obligation  of  Company  to  consummate and effect the Merger shall be
subject  to  the  satisfaction  at or prior to the Effective Time of each of the
following  conditions,  any  of  which may be waived, in writing, exclusively by
Company:

     (a)  Representations  and  Warranties.  Each representation and warranty of
          ---------------------------------
Parent  and  Merger Sub contained in this Agreement (i) shall have been true and
correct  as  of the date of this Agreement and (ii) shall be true and correct on
and  as  of  the  Closing  Date with the same force and effect as if made on the
Closing  Date.  The Company shall receive a certificate to such effect signed on
behalf  of  Parent  by  an  authorized  officer  of  Parent.


                                       28

     (b)  Agreements  and Covenants.  Parent and Merger Sub shall have performed
          --------------------------
or  complied in all material respects with all agreements and covenants required
by  this  Agreement  to be performed or complied with by them on or prior to the
Closing  Date,  and  Company  shall  have  received a certificate to such effect
signed  on  behalf  of  Parent  by  an  authorized  officer  of  Parent.

     (c)  Legal  Opinion.     The  Company  shall  receive  an  acceptable legal
          --------------
opinion  with  respect  to  the  issuance  of  Parent  Common  Stock.

     6.3  ADDITIONAL CONDITIONS TO THE OBLIGATIONS OF PARENT AND MERGER SUB.

     The  obligations  of  Parent  and  Merger  Sub to consummate and effect the
Merger  shall be subject to the satisfaction of Parent and Merger Sub of each of
the  following  conditions at or prior to the Effective Time, unless  Parent, in
its  sole  discretion,  waives  in  writing  any  of  the  following conditions:

     (a)  Representations  and  Warranties.  Each representation and warranty of
          ---------------------------------
Company  contained  in this Agreement (i) shall have been true and correct as of
the  date  of this Agreement and (ii) shall be true and correct on and as of the
Closing  Date with the same force and effect as if made on and as of the Closing
Date.  The Parent shall receive a certificate to such effect signed on behalf of
the  Company  by  the  directors  of  Company.

     (b)  Agreements and Covenants.  Company shall have performed or complied in
          -------------------------
all  material  respects  with  all  agreements  and  covenants  required by this
Agreement  to  be  performed  or  complied with by it at or prior to the Closing
Date,  and  Parent  shall  have  received a certificate to such effect signed on
behalf  of  Company  by  the  directors  of  Company.

     (c)  Consents  and  Opinions.  Company  shall  have  obtained all consents,
          ------------------------
waivers  and  approvals  required  in  connection  with  the consummation of the
transactions  contemplated hereby, including those agreements listed on Schedule
2.4 of Company Schedule.  Additionally, Parent shall have received an acceptable
legal  opinion  with  respect  to  corporate  matters,  including  the  License
Agreement.

     (d)  Audited Financial Statement.  The Company shall have provided to
          ---------------------------
Parent on or before Closing, an unqualified opinion, except for any going
concern qualifications, and financial statements, including pro-forma financial
data that satisfy Parent's obligations under Item 7 of Form 8-K.

     (e)  Dissenting  Shares.  There  shall  be  no  more than 2% of the Company
          ------------------
Common  Stock  that  are  Dissenting  Shares.

     (f)  Intellectual  Property  Opinion.  The  Parent  shall  have received an
          -------------------------------
acceptable  opinion,  as  determined  in  its  sole discretion from intellectual
property  counsel,  with  respect  to  Company  Intellectual  Property.

     (g)  Preferred Stock Designation Amendment.  The Company shall have amended
          -------------------------------------
its  Certificate of Designation for its Series A Preferred Stock to provide that
the valuation of consideration as stated in Section  2(c)(ii) of the Certificate
of  Designation  shall be fully satisfied by the issuance of the shares pursuant
to  Section  1.6(a)  hereof.

     (h)  Termination  of  Certain Agreements.  The Company shall have waived or
          -----------------------------------
caused to be waived any prior defaults and terminated or caused to be terminated
the  following  agreements:   (i) the Stockholders Agreement, dated September 5,
2001  between  the  Company  and  certain  securities holders; (ii) the Series A
Preferred Stock Purchase Agreement, dated March 28, 2002 between the Company and
certain  of  its  securities holders; (iii) the Voting Agreement, dated April 5,
2002  between  the  Company  and  certain  of  its  securities holders; (iv) the
Investors  Rights Agreement, dated April 5, 2002 between the Company and certain
of  its  securities  holders;  and  (v)  the  Right of First Refusal and Co-Sale
Agreement, dated April 5, 2002 between the Company and certain of its securities
holders.  Further  Company  shall  terminate  or  caused  to  be  terminated any
agreements  inconsistent  with  its  representations  and  warranties  herein.


                                       29

     (i)  Execution  of  Consulting  Agreement  with  Jingwu Zhang.  The Company
          --------------------------------------------------------
shall  obtain  a three (3) year consulting agreement with Jingwu Zhang, with the
same terms and conditions of the Consulting Agreement between Company and Jingwu
Zhang,  dated  September  5,  2001,  unless  Parent agrees in writing otherwise.

     (j)  Baylor  License  Agreement.  The  Company  shall  receive  a  written
          ---------------------------
acknowledgement  from  Baylor that the Company is not and has not been in breach
or  default with the License Agreement, that this Agreement will not result in a
breach, default, termination or any other way affect this License Agreement, and
agree to affect an amendment to Article 16 of License, regarding board seats, if
requested.

     (k)  Completion of Clinical Due Diligence.  Parent shall have completed its
          ------------------------------------
review  of  Company's clinical data and receive a satisfactory verification by a
third  party  appointed  by  Parent,  in  its  sole  discretion.

     (l)  Release  Agreement.  Holders  of  at  least  98% of the Company Common
          ------------------
Stock  and Company Preferred Stock shall have executed the Release Agreement, in
the  form  attached  hereto  as  Exhibit  E.

     (m)  Certificate regarding Redman Termination Agreement.  The Company shall
          --------------------------------------------------
provide  a  certificate  executed  by  the  directors of the Company stating the
Redman  Termination  Agreement  has  not  been  amended  or  modified.

     (n)  Company  Warrants.  Termination  of all of the Company Warrants as set
          -----------------
forth  in  Schedule  2.2  of  the  Company  Schedules,  pursuant  to  a  warrant
termination  agreement  in  the  form  attached  hereto  as  Exhibit  F.

     (o)  Certificate  for  Company  Options.  The  Company  shall  provide  a
          ----------------------------------
certificate  executed  by  the  directors of the Company stating that all of the
Company Options shall have been either vested and fully exercised or terminated.

     (p)  Escrow  Agreement.  The Company shall provide the Escrow Agreement, in
          -----------------
the  form  attached  hereto as Exhibit G, executed by the stockholders of Opexa.

     (q)  Bringdown  Certificate.  The  Company  shall  provide  a  certificate
          ----------------------
executed  by  the  Secretary  and Chief Executive Officer stating any changes to
Exhibit  C.

     (r)  Correspondence  relating  to the Food and Drug Authority.  The Company
          --------------------------------------------------------
shall  provide a list of all of the Company's regulatory correspondence relating
to  Food  and  Drug Laws received from any Food and Drug Authority over the last
five  (5)  years.

                                   ARTICLE VII

                        TERMINATION, AMENDMENT AND WAIVER

     7.1  TERMINATION.

     This  Agreement  may be terminated at any time prior to the Effective Time,
whether  before  or after the requisite approval of the shareholders of Company:

     (a)  by  mutual  written consent duly authorized by the Boards of Directors
of  Parent  and  Company;

     (b)  by  either  Company  or  Parent  if  the  Merger  shall  not have been
consummated  by  the  Effective Time for any reason; provided, however, that the
right  to  terminate  this  Agreement  under  this  Section  7.1(b) shall not be
available to any party whose action or failure to act has been a principal cause
of  or resulted in the failure of the Merger to occur on or before such date and
such  action  or failure to act constitutes a material breach of this Agreement;

     (c)  by either Company or Parent if a Governmental Entity shall have issued
an  order,  decree  or  ruling or taken any other action, in any case having the
effect  of  permanently  restraining,  enjoining  or  otherwise  prohibiting the
Merger,  which order, decree, ruling or other action is final and nonappealable;


                                       30

     (d)  by Company, if the conditions set forth in Section 6.1 or 6.2 have not
been satisfied by the Effective Time or earlier as of the time such condition is
required  hereunder  to be satisfied or such condition is or becomes impossible;

     (e)  by Company, upon a breach of any representation, warranty, covenant or
agreement  on  the  part  of  Parent  set  forth  in  this  Agreement, or if any
representation  or  warranty  of Parent shall have become untrue, in either case
such  that  the  conditions  set  forth  in  Section 6.2 (a) or (b) would not be
satisfied as of the time of such breach or as of the time such representation or
warranty shall have become untrue, provided, that if such inaccuracy in Parent's
representations  and  warranties  or breach by Parent is curable by Parent, then
Company  may  not  terminate this Agreement under this Section 7.1(e) for thirty
(30)  days  after  delivery  of  written  notice  from Company to Parent of such
breach,  provided  Parent continues to exercise best efforts to cure such breach
(it  being  understood that Company may not terminate this Agreement pursuant to
this paragraph (e) if such breach by Parent is cured during such thirty (30)-day
period);

     (f)  by  Parent, upon a breach of any representation, warranty, covenant or
agreement  on  the  part  of  Company  set  forth  in  this Agreement, or if any
representation  or  warranty of Company shall have become untrue, in either case
such  that  the conditions set forth in Section 6.3(a), (b), or (c) would not be
satisfied as of the time of such breach or as of the time such representation or
warranty  shall  have  become  untrue,  provided,  that  if  such  inaccuracy in
Company's  representations  and  warranties  or  breach by Company is curable by
Company,  then Parent may not terminate this Agreement under this Section 7.1(f)
for  thirty (30) days after delivery of written notice from Parent to Company of
such  breach,  provided  Company continues to exercise best efforts to cure such
breach  (it  being  understood  that  Parent  may  not  terminate this Agreement
pursuant  to  this  paragraph (f) if such breach by Company is cured during such
thirty  (30)-day  period);

     (g)  by  Parent  or  Company  (and,  with respect to the Company, only upon
payment of the fee set forth in Section 7.3(b) below), if the Board of Directors
of  Company  determines  to  enter into a definitive agreement with respect to a
Superior  Proposal  in  accordance  with  Section  5.4  hereof;

     (h)  by  Parent  if  the  conditions  of  Section  6.1  or 6.3 has not been
satisfied  by  the  Effective  Time  or earlier as of the time such condition is
required  hereunder  to be satisfied or such condition is or becomes impossible;

     (i)  by  Parent  or  Company  any  time  on  or  after  October  31,  2004.

     7.2  NOTICE OF TERMINATION; EFFECT OF TERMINATION.

     Any termination of this Agreement under Section 7.1 above will be effective
immediately  upon the delivery of written notice of the terminating party to the
other parties hereto (or such later time as may be required by Section 7.1).  In
the  event of the termination of this Agreement as provided in Section 7.1, this
Agreement  shall  be  of  no further force or effect, except (i) as set forth in
this Section 7.2, Section 5.3(a), Section 7.3 and Article 8, each of which shall
survive the termination of this Agreement, and (ii) nothing herein shall relieve
any party from liability for fraud in connection with, or any willful breach of,
this  Agreement.

     7.3  FEES AND EXPENSES.

     (a)  General.  Except  as  set  forth  in  this  Section  7.3, all fees and
          --------
expenses  incurred  in  connection  with  this  Agreement  and  the transactions
contemplated  hereby  shall be paid by the party incurring such expenses whether
or  not  the  Merger  is  consummated.

     (b)  Termination Fee Payable by Company.  In the event that (A) the Company
          -----------------------------------
shall terminate this Agreement pursuant to Section 7.1(g), or (B) this Agreement
shall  be  terminated  pursuant  to Section 7.1(d) (other than for a termination
resulting  from  the  conditions  set forth in Section 6.2 not being met, unless
such  failure  is  based  upon  or  caused  by  any action of the Company or its
shareholders)  and  within  12  months  after  any  such termination pursuant to
Section  7.1(d), Company shall enter into a definitive agreement with respect to
any  Company  Acquisition,  then, in the case of clause (A), promptly after such
termination,  or  in  the  case  of  clause  (B),


                                       31

concurrently  with  the  execution  of  such  Company  Acquisition (signing of a
definitive  purchase  agreement),  Company  shall pay to Parent $500,000 in cash
(the  "TERMINATION  FEE").

     7.4  AMENDMENT.

     Subject  to  applicable  law,  this Agreement may be amended by the parties
hereto  at any time by execution of an instrument in writing signed on behalf of
each  of  Parent,  Merger  Sub  and  Company

     7.5  EXTENSION; WAIVER.

     At  any  time  prior  to  the  Effective Time, any party hereto may, to the
extent  legally  allowed,  (i) extend the time for the performance of any of the
obligations  or  other  acts  of  the  other  parties  hereto,  (ii)  waive  any
inaccuracies  in the representations and warranties made to such party contained
herein  or  in any document delivered pursuant hereto and (iii) waive compliance
with any of the agreements or conditions for the benefit of such party contained
herein.  Any  agreement  on  the part of a party hereto to any such extension or
waiver  shall  be  valid only if set forth in an instrument in writing signed on
behalf  of such party.  Delay in exercising any right under this Agreement shall
not  constitute  a  waiver  of  such  right.

                                  ARTICLE VIII

                                 INDEMNIFICATION

     8.1  SURVIVAL.

     The  representations and warranties of the parties hereto contained in this
Agreement  shall  survive  the  Closing  until 12 months after the Closing Date.
Notwithstanding  the  preceding  sentence,  any  representation  or  warranty in
respect  of  which  indemnity  may  be sought under this Agreement shall survive
beyond  the time at which it would otherwise terminate pursuant to the preceding
sentence,  if  notice  of  the  inaccuracy or breach thereof giving rise to such
right  of  indemnity  shall  have  been  given  to  the  party against whom such
indemnity  may  be  sought  prior  to  the  scheduled  termination  of  such
representation  or  warranty, as applicable. The covenants and agreements of the
parties  (including,  without  limitation,  the  covenants and agreements of the
parties  set  forth in this Article 8) contained in this Agreement shall survive
for  12  months.

     8.2  OBLIGATION TO INDEMNIFY.

     Pursuant  to  the  Escrow  Agreement,  certain shareholders (the "ESCROWING
SHAREHOLDERS")  will  escrow  a  total  of 250,000 shares of Parent Common Stock
("ESCROWED  SHARES") to be used to satisfy the Company's obligation to indemnify
under  this Article 8.  The Company agrees to indemnify and hold harmless Parent
and  its  respective  officers,  directors,  employees,  accountants,  counsel,
consultants,  advisers and agents ("REPRESENTATIVES") against and agrees to hold
each  of  them  harmless  from  any  and all damage, loss, liability and expense
(including,  without  limitation,  reasonable  expenses  of  investigation  and
reasonable  attorney's  fees  and  expenses  related  to  the  matter  at issue)
including  interest  ("LOSSES"),  incurred  or  suffered by them arising out of,
based  on  or  in  connection  with any misrepresentation or breach of warranty,
covenant or agreement made or to be performed by the Company; provided, however,
                                                              --------- --------
that  the  Company  shall  not  have  any liability for Losses under Section 8.2
unless  the  aggregate  of all Losses for which the Company would be liable, but
for  this  provision,  exceeds  on a cumulative basis an amount equal to $50,000
(the  "INDEMNIFICATION  BASKET"),  and  then  only to the extent of such excess;
provided, further, that the Indemnification Basket shall not apply to the entire
    ----- --------
amount  of  any  individual  item  of Loss that is greater than $25,000, or such
other  items  of  Loss  that would, when aggregated with each other item of Loss
arising from the same underlying facts, events or circumstances, equal or exceed
$25,000;  and,  provided, further, that the maximum amount for which the Company
                --------- --------
shall  be  liable  in  the aggregate under this Section 8.2 shall not exceed the
value  of  the  Escrowed  Shares  (the  "INDEMNIFICATION  CAP").

     8.3  INDEMNIFICATION PROCEDURES.

     (a)  The Escrowing Shareholders will agree to act as the indemnifying party
for  the  purposes  of this Article 8 and will designate a representative in the
Escrow  Agreement  for  such  purpose  (the  "INDEMNIFYING  PARTY").  The


                                       32

Parent (the "INDEMNIFIED PARTY") agrees to give the Indemnifying Party notice in
writing  of  the  assertion  of  any  claim  or  demand  made  by, or an action,
proceeding  or  investigation  instituted  by,  any  person  not a party to this
Agreement  (a  "THIRD  PARTY CLAIM") in respect of which indemnity may be sought
under  such  Section  promptly  after such Indemnified Party learns of the Third
Party  Claim;  provided,  however,  that  failure  to give such notice shall not
               ---------  --------
affect  the  indemnification  provided  hereunder  except  to  the  extent  the
Indemnifying  Party  shall  have  been  actually  prejudiced as a result of such
failure.  Thereafter,  the  Indemnified  Party shall deliver to the Indemnifying
Party, as promptly as practicable after the Indemnified Party's receipt thereof,
copies  of  all  notices  and documents (including court papers) received by the
Indemnified  Party  relating  to  the  Third  Party  Claim.

     (b)  If  a  Third  Party  Claim  is  made against an Indemnified Party, the
Indemnifying  Party  will be entitled to participate in the defense thereof and,
by  providing  notice to the Indemnified Party delivered within 20 business days
after  the  receipt  of  notice of such Third Party Claim, to assume the defense
thereof  with counsel selected by the Indemnifying Party; provided that (i) such
counsel  is  approved  by  the  Indemnified  Party  (such  approval  not  to  be
unreasonably  withheld  or delayed), (ii) the Indemnified Party is kept informed
of  all  developments, and is furnished with copies of all documents and papers,
related  thereto  and  is  given  the  right  to  participate in the defense and
investigation  thereof  as  provided below, and (iii) such counsel proceeds with
diligence  and in good faith with respect thereto. Should the Indemnifying Party
so  elect  to  assume the defense of a Third Party Claim, the Indemnifying Party
will  not as long as it conducts such defense be liable to the Indemnified Party
for  legal expenses subsequently incurred by the Indemnified Party in connection
with  the  defense  thereof. If the Indemnifying Party assumes such defense, the
Indemnified Party shall have the right to participate in the defense thereof and
to  employ  its  own  counsel,  separate  from  the  counsel  employed  by  the
Indemnifying  Party at its own expense, except that the Indemnifying Party shall
bear  the  expense  of  such  separate  counsel if (A) in the written opinion of
counsel  to  the  Indemnified  Party  reasonably  acceptable to the Indemnifying
Party,  use  of  counsel of the Indemnifying Party's choice would be expected to
give  rise  to  a conflict of interest or (B) there are or may be legal defenses
available  to  the  Indemnified  Party  that are different from or additional to
those  available  to  the  Indemnifying  Party.  The Indemnifying Party shall be
liable  for  the  fees and expenses of counsel employed by the Indemnified Party
for  any  period during which the Indemnifying Party has not assumed the defense
thereof.  If  the  Indemnifying  Party  chooses to defend or prosecute any Third
Party  Claim,  all  of  the  parties  hereto  shall  cooperate in the defense or
prosecution  thereof. Such cooperation shall include the retention and (upon the
Indemnifying Party's request) the provision to the Indemnifying Party of records
and  information  that  are  reasonably  relevant to such Third Party Claim, and
making  employees available on a mutually convenient basis to provide additional
information and explanation of any material provided hereunder. The Indemnifying
Party shall be authorized to consent to a settlement of any Third Party Claim as
to  which  the Indemnifying Party has assumed the defense in accordance with the
terms  of Section 8.3, without the consent of any Indemnified Party, but only to
the  extent  that  such  settlement (i) provides solely for the payment of money
damages  by  the  Indemnifying  Party, and for payment to be concurrent with the
effectiveness  of  the  settlement  and  (ii) provides a complete release of the
Company  potentially  affected  by  such Third Party Claim from all matters that
were  or  could  have  been  asserted  in connection with such claims. Except as
provided  in  the foregoing sentence, settlement or consent to entry of judgment
shall  require  the  prior  approval  of  the  Indemnified  Party.

     8.4  PROCEDURES FOR DIRECT CLAIMS.

     In the event any Indemnified Party shall have a claim for indemnity against
the  Company  that  does  not involve a Third Party Claim, the Indemnified Party
shall  deliver  notice  of  such  claim  with  reasonable  promptness  to  the
Indemnifying  Party.  Such  notice  referred  to in the preceding sentence shall
state  the  relevant  facts  and  include  therewith  relevant  documents  and a
statement  in  reasonable detail as to the basis for the indemnification sought.
The  failure  by any Indemnified Party so to notify the Indemnifying Party shall
not  relieve  the Indemnifying Party from any liability that it may have to such
Indemnified  Party  with respect to any claim made pursuant to this Section 8.4,
it  being  understood  that  notices  for  claims  in  respect  of a breach of a
representation  or  warranty  must  be  delivered prior to the expiration of the
survival  period  for such representation or warranty. If the Indemnifying Party
does  not  notify  the  Indemnified  Party within 20 business days following its
receipt of such notice that the Indemnifying Party disputes its liability to the
Indemnified  Party  under  this  Section, the claim specified by the Indemnified
Party  in  such  notice  shall  be  conclusively  deemed  a  liability  of  the
Indemnifying  Party  under  this Section 8, and the Indemnifying Party shall pay
the  amount of such liability to the Indemnified Party on demand or, in the case
of  any notice in which the amount of the claim (or any portion of the claim) is
estimated,  on such later date when the amount of such claim (or such portion of
such  claim)  becomes  finally  determined.


                                       33

     8.5  OTHER INDEMNIFICATION PROVISIONS.


     The  indemnities  provided  in this Agreement shall survive the Closing and
are  in  addition  to,  and  not  in derogation of, any other legal or equitable
remedy  any party may have with respect to the transactions contemplated by this
Agreement.


     8.6  CERTAIN LIMITATIONS.

     The  amount  of any Losses for which indemnification is provided under this
Agreement  shall  be net of any amounts recovered by the Indemnified Party under
insurance  policies  with  respect  to such Losses and shall be (i) increased to
take  account  of  any  tax  cost incurred (grossed up for such increase) by the
Indemnified  Party arising from the receipt of indemnity payments hereunder, and
(ii)  reduced  to  take  account  of any tax benefit realized by the Indemnified
Party  arising  from the incurrence or payment of any such Losses. Such tax cost
or  tax  benefit,  as  the case may be, shall be computed for any year using the
Indemnified Party's actual tax liability with and without (i) the receipt of any
indemnification payments made pursuant to this Agreement and (ii) the incurrence
or  payment  of  any  Losses  for  which  indemnification is provided under this
Agreement  in  such  year.  In  the  event  that  the Indemnified Party actually
realizes a tax cost or tax benefit for a year(s) subsequent to the year in which
the  indemnity  payment  is made, the Indemnifying Party shall pay the amount of
such tax cost or the Indemnified Party shall pay the amount of such tax benefit,
as  the  case  may  be,  in  such  subsequent  year(s).

                                   ARTICLE IX

                               GENERAL PROVISIONS

     9.1  SURVIVAL OF REPRESENTATIONS AND WARRANTIES.

     The  representations  and  warranties  of  Company,  Parent  and Merger Sub
contained  in this Agreement shall terminate at the Effective Time, and only the
covenants  that  by  their  terms  survive  the Effective Time shall survive the
Effective  Time.

     9.2  NOTICES.

     All  notices  and  other  communications  hereunder shall be in writing and
shall be deemed given if delivered personally or by commercial delivery service,
or  sent  via  telecopy  (receipt  confirmed)  to  the  parties at the following
addresses  or telecopy numbers (or at such other address or telecopy numbers for
a  party  as  shall  be  specified  by  like  notice):


     (a)  if to Parent or Merger Sub, to:

          PharmaFrontiers Corp.
          18205 Burkhardt Road
          Tomball, TX  77377
          Attention: David B. McWilliams
          Facsimile No.: (281) 290-0940

          with copies to:

          Brewer & Pritchard, P.C.
          Three Riverway, 18th Floor
          Houston, Texas  77056
          Attention: Thomas C. Pritchard / Peter Talosig
          Facsimile No.: (713) 209-2928


                                       34

     (b)  if to Company, to:

          Opexa Pharmaceuticals, Inc.
          835 Greens Parkway, Suite 150
          Houston, Texas  77067
          Attention: Michael Redman
          Facsimile No.: (281) 872-8585

          with copies to:

          Winstead Sechrest & Minick, P.C.
          Jeffrey R. Harder
          600 Town Center One
          1450 Lake Robbins Drive
          The Woodlands,  Texas 77380


     9.3  INTERPRETATION; DEFINITIONS.

     (a)  When a reference is made in this Agreement to Exhibits, such reference
shall  be  to  an  Exhibit to this Agreement unless otherwise indicated.  When a
reference  is  made  in this Agreement to Sections, such reference shall be to a
Section  of  this  Agreement.  Unless  otherwise  indicated the words "include,"
"includes"  and  "including" when used herein shall be deemed in each case to be
followed  by the words "without limitation."  The table of contents and headings
contained in this Agreement are for reference purposes only and shall not affect
in  any  way the meaning or interpretation of this Agreement.  When reference is
made  herein  to  "the business of" an entity, such reference shall be deemed to
include  the  business  of  all direct and indirect subsidiaries of such entity.
Reference to the subsidiaries of an entity shall be deemed to include all direct
and  indirect  subsidiaries  of  such  entity.

     (b)  For  purposes  of  this  Agreement:

     (i)  the  term  "KNOWLEDGE"  means  with  respect  to  a party hereto, with
respect  to  any  matter  in  question,  the  actual  knowledge of the executive
officers  of  such  party;

     (ii) the  term  "MATERIAL  ADVERSE  EFFECT" when used in connection with an
entity  means  any  change, event, violation, inaccuracy, circumstance or effect
that  is,  or  is  reasonably  likely to be, materially adverse to the business,
assets, liabilities, financial condition or results of operations of such entity
and its subsidiaries taken as a whole; provided, however, that in no event shall
(A)  a  decrease  in  such entity's stock price or the failure to meet or exceed
Wall  Street  research  analysts'  or  such  entity's internal earnings or other
estimates  or  projections in and of itself constitute a Material Adverse Effect
or  (B)  any  change,  event, violation, inaccuracy, circumstance or effect that
results  from  (x)  changes affecting the industry in which such entity operates
generally  (which  changes  do  not  disproportionately affect such entity), (y)
changes  affecting  the  United  States  economy  generally  or  (z)  the public
announcement  or  pendency  of the Merger, constitute a Material Adverse Effect;

     (iii) the  term  "PERSON" shall mean any individual, corporation (including
any  non-profit  corporation), general partnership, limited partnership, limited
liability  partnership,  joint  venture,  estate,  trust, company (including any
limited  liability  company  or  joint stock company), firm or other enterprise,
association,  organization,  entity  or  Governmental  Entity.

     9.4  COUNTERPARTS.

     This  Agreement  may  be executed in one or more counterparts, all of which
shall  be  considered one and the same agreement and shall become effective when
one  or  more counterparts have been signed by each of the parties and delivered
to  the other party, it being understood that all parties need not sign the same
counterpart.


                                       35

     9.5  ENTIRE AGREEMENT; THIRD PARTY BENEFICIARIES.

     This Agreement and the documents and instruments and other agreements among
the  parties  hereto  as  contemplated  by  or referred to herein, including the
Company  Schedules  and the Parent Schedules (a) constitute the entire agreement
among  the  parties  with respect to the subject matter hereof and supersede all
prior  agreements  and  understandings, both written and oral, among the parties
with  respect  to  the  subject matter hereof, including but not limited to that
certain  Letter  of Intent dated July 2, 2004 between Parent and the Company, it
being understood that the Confidentiality Agreement shall continue in full force
and  effect  until  the  Closing  and  shall  survive  any  termination  of this
Agreement;  and (b) does not create, and shall not be construed as creating, any
rights  enforceable  by  any  person  not  a  party  to  this  Agreement.

     9.6  SEVERABILITY.

     In  the  event  that  any  provision  of this Agreement, or the application
thereof,  becomes  or  is  declared  by  a court of competent jurisdiction to be
illegal, void or unenforceable, the remainder of this Agreement will continue in
full  force and effect and the application of such provision to other persons or
circumstances  will  be interpreted so as reasonably to effect the intent of the
parties hereto.  The parties further agree to replace such void or unenforceable
provision  of  this  Agreement  with a valid and enforceable provision that will
achieve,  to  the extent possible, the economic, business, and other purposes of
such  void  or  unenforceable  provision.

     9.7  OTHER REMEDIES; SPECIFIC PERFORMANCE.

     Except  as otherwise provided herein, any and all remedies herein expressly
conferred  upon  a party will be deemed cumulative with and not exclusive of any
other  remedy  conferred  hereby,  or  by law or equity upon such party, and the
exercise  by  a  party  of  any one remedy will not preclude the exercise of any
other  remedy.  The  parties hereto agree that irreparable damage would occur in
the  event  that  any  of the provisions of this Agreement were not performed in
accordance  with  their  specific  terms  or  were  otherwise  breached.  It  is
accordingly  agreed  that the parties shall be entitled to seek an injunction or
injunctions  to  prevent  breaches of this Agreement and to enforce specifically
the  terms  and provisions hereof in any court of the United States or any state
having  jurisdiction,  this  being in addition to any other remedy to which they
are  entitled  at  law  or  in  equity.

     9.8  GOVERNING LAW.

     Except  to  the extent mandatorily governed by Delaware Law, this Agreement
shall  be  governed by and construed in accordance with the laws of the State of
Texas,  regardless  of  the  laws  that  might otherwise govern under applicable
principles  of  conflicts  of  law  thereof.

     9.9  ARBITRATION.

     If a dispute should arise, all claims, disputes, controversies, differences
or  other  matters in question arising out of the Agreement to each other in the
matters  stated  in  this  Agreement  (the  claims)  shall  be  settled finally,
completely  and conclusively by arbitration in Houston, Harris County, Texas, in
accordance  with  the  Commercial  Arbitration Rules of the American Arbitration
Association  (the "Rules"), by one or more arbitrators chosen in accordance with
the  Rules.  Arbitration  shall  be  initiated  by  written  demand by the party
seeking  arbitration.  This  Agreement  to  arbitrate  shall  be  specifically
enforceable  only  in the District Court of Harris County, Texas.  A decision of
the  arbitrator  or arbitrators shall be final, conclusive and binding on Parent
and  the  Company,  and judgment may be entered thereon in the District Court of
Harris  County,  Texas, to enforce such decision and the benefits thereof.  Upon
appointment,  the  arbitrators  shall  then  proceed  to  decide the arbitration
subjects  in accordance with the Rules.  Any arbitration held in accordance with
this paragraph shall be private and confidential and no person shall be entitled
to  attend  the  hearings  except the arbitrator(s), the stenographer, if one is
requested,  Parent,  Company, and any designated representatives of the parties.
The  matters  submitted for arbitration, the hearings and proceedings thereunder
and  the  arbitration award shall be kept and maintained in strictest confidence
by  the  parties  and  shall  not be discussed, disclosed or communicated to any
persons.  On  request  of  either  party,  the record of the proceeding shall be
sealed  and  may  not  be  disclosed except insofar, and only insofar, as may be
necessary  to  enforce  the  award of the arbitrators and any judgment enforcing
such  award.  If  counsel  is  required  to


                                       36

seek the enforcement of this agreement or this particular section, counsel shall
be  entitled  to  recover its (his) reasonable and necessary attorneys' fees and
costs  from  the  opposing  party.

     9.10 RULES OF CONSTRUCTION.

     The  parties hereto agree that they have been represented by counsel during
the  negotiation  and  execution  of  this  Agreement  and, therefore, waive the
application  of  any  law, regulation, holding or rule of construction providing
that ambiguities in an agreement or other document will be construed against the
party  drafting  such  agreement  or  document.

     9.11 ASSIGNMENT.

     No  party may assign either this Agreement or any of its rights, interests,
or  obligations  hereunder  without  the  prior  written  approval  of the other
parties.  Subject  to  the  preceding  sentence, this Agreement shall be binding
upon  and  shall inure to the benefit of the parties hereto and their respective
successors  and  permitted  assigns.

     9.12 UNDERSTANDING AND ADVICE OF COUNSEL.

     The  Company  and  Parent  have  had  the  assistance  of  separate counsel
(including,  without limitation, tax counsel) in carefully reviewing, discussing
and  considering  all  terms  of  this  Agreement; and, with the benefit of such
advice  by  counsel,  who has read and considered this Agreement, have agreed to
execute  the same.  This Agreement shall not be construed against or unfavorably
to  any party because of such party's involvement in the preparation or drafting
of  this  Agreement.

     9.13 WAIVER.

     Any  waiver  by  any  party  of a breach of any provision of this Agreement
shall  not operate as or be construed to be a waiver of any other breach of that
provision  or  of  any  breach  of  any  other provision of this Agreement.  The
failure of a party to insist upon strict adherence to any term of this Agreement
on  one  or more occasions will not be considered a waiver or deprive that party
of  the  right  thereafter  to  insist upon strict adherence to that term or any
other term of this Agreement.  Any waiver must be in writing and, in the case of
a corporate party, be authorized by a resolution of the Board of Directors or by
an  officer  of  the  waiving  party.

     9.14  HEADINGS.

     The  headings of this Agreement are solely for convenience of reference and
shall  be  given  no  effect  in  the  construction  or  interpretation  of this
Agreement.


                                       37

     IN  WITNESS  WHEREOF,  the  parties hereto have caused this Agreement to be
executed  by  their  duly  authorized  respective  officers as of the date first
written  above.


PHARMAFRONTIERS CORP.


By:  /S/  DAVID B. MCWILLIAMS
     ------------------------
     David B. McWilliams, President

Address:  18205 Burkhardt Road
          Tomball, TX  77377


PHARMA ACQUISITION CORP.


By:  /S/  DAVID B. MCWILLIAMS
     ------------------------
     David B. McWilliams, President

Address:  18205 Burkhardt Road
          Tomball, TX  77377


OPEXA PHARMACEUTICALS, INC.


By:  /S/  MICHAEL REDMAN
     --------------------
     Michael Redman, President

Address:  835 Greens Parkway, Suite 150
          Houston, TX  77067


                                       38