SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON D.C. 20549


                                    FORM 8-K


               CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                           THE SECURITIES ACT OF 1934



    DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED)    September 30, 1997
                                                     -----------------------



                          PREMIER LASER SYSTEMS, INC.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)



        California                      0-25242                 33-0472684
- ----------------------------    ------------------------    ------------------
(State or other jurisdiction    (Commission File Number)     (I.R.S. Employer
    of incorporation)                                       Identification No.)



                    3 Morgan, Irvine, California           92718
              ----------------------------------------   ----------
              (Address of principal executive offices)   (Zip Code)



     Registrant's telephone number, including area code      (714) 859-0656
                                                        -----------------------



                                 Not Applicable
         -------------------------------------------------------------
         (Former name or former address, if changed since last report.)

 
ITEM 2.  ACQUISITION OR DISPOSITION OF ASSETS

     On September 30, 1997, Premier Laser Systems, Inc. (the "Company")
acquired EyeSys Technologies, Inc. ("EyeSys") through the merger of Premier
Acquisition of Delaware, Inc. ("PAI"), a wholly owned subsidiary of the Company,
into EyeSys (the "Merger"). Upon the effective date of the Merger, EyeSys became
a wholly owned subsidiary of the Company. The Merger was effected pursuant to an
Agreement and Plan of Merger dated April 24, 1997 by and among the Company, PAI
and EyeSys, as amended.

     The consideration paid in the merger consisted of approximately 1,236,668 
shares of the Company's Class A Common Stock which was distributed among: 
(i) holders of stock and notes of EyeSys, (ii) certain creditors and claimants
of EyeSys and (iii) employees of EyeSys entitled to bonuses for continued
employment following the Merger. Options to purchase Class A Common were also
issued in exchange for outstanding options and warrants to purchase EyeSys
common stock.

     EyeSys designs, develops and markets a line of noninvasive corneal
topography systems for use by ophthalmologists and optometrists in surgical
planning and evaluation, diagnosis of corneal pathologies and contact lens
fitting. Premier will continue the operation of EyeSys' business following the
Merger; however, EyeSys' manufacturing and operational facilities and personnel
will be relocated to Premier's headquarters in Irvine, California.

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ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS.

    A.   Financial Statements of EyeSys.  Financial Statements of EyeSys
         ------------------------------                                 
         prepared in accordance with Regulation S-X and required to be filed
         pursuant to this item are not available at this time. Such financial
         statements will be filed by the Company as soon as practicable by an
         amended Current Report on Form 8-K/A which will be filed within sixty
         (60) days after the date this Current Report on Form 8-K was required
         to be filed.

    B.   Pro Forma Financial Information.  The pro forma combined financial 
         -------------------------------                         
         financial statements of the Company required to be filed pursuant to
         this item are not available at this time. Such pro forma financial
         information will be filed by the Company as soon as practicable by an
         amended Current Report on Form 8-K/A which will be filed within sixty
         (60) days after the date this Current Report on Form 8-K was required
         to be filed.

    C.   Exhibits
         --------

    Exhibit
    Number                          Description
    ------                          -----------

    2.1      Agreement and Plan of Merger dated as of April 24, 1997 among
             Premier Laser Systems, Inc., EyeSys Technologies, Inc. and
             Premier Acquisition of Delaware, Inc. (incorporated herein by
             this reference to Exhibit 2.1 to the Registrant's Registration
             Statement on Form S-4, Registration No. 333-29573).

    2.2      First Amendment to Agreement and Plan of Merger dated as of
             August 6, 1997 among Premier Laser Systems, Inc., EyeSys
             Technologies, Inc. and Premier Acquisition of Delaware, Inc.
             (filed herewith).

    2.3      Second Amendment to Agreement and Plan of Merger dated as of
             September 16, 1997 among Premier Laser Systems, Inc., EyeSys
             Technologies, Inc. and Premier Acquisition of Delaware, Inc.
             (filed herewith).

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SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto.

                                 PREMIER LASER SYSTEMS, INC.


October 14, 1997                 /s/ Michael L. Hiebert
                                 -------------------------------------------
                                 Michael L. Hiebert, Chief Financial Officer

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                               INDEX TO EXHIBITS
 
 
                                                                    SEQUENTIALLY
                                                                      NUMBERED
EXHIBIT                          DESCRIPTION                            PAGE
- -------                          -----------                        ------------
                                                               
2.1         Agreement and Plan of Merger dated as of April 24, 1997 
            among Premier Laser Systems, Inc., EyeSys Technologies, 
            Inc. and Premier Acquisition of Delaware, Inc. 
            (incorporated herein by this reference to Exhibit 2.1 
            to the Registrant's Registration Statement on form S-4, 
            Registration No. 333-29573).

2.2         First Amendment to Agreement and Plan of Merger dated 
            as of August 6, 1997 among Premier Laser Systems, Inc., 
            EyeSys Technologies, Inc. and Premier Acquisition of 
            Delaware, Inc. (filed herewith).

2.3         Second Amendment to Agreement and Plan of Merger dated 
            as of September 16, 1997 among Premier Laser Systems, 
            Inc., EyeSys Technologies, Inc. and Premier Acquisition 
            of Delaware, Inc. (filed herewith).
 

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