- --------------------------------------------------------------------------------

                                 UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549

                                   FORM 10-Q

(MARK ONE)

[X]   Quarterly Report Pursuant to Section 13 or 15(d) of the Securities
      Exchange Act of 1934.
      For the quarterly period ended March 31, 1999.

                                      OR
                                        
[_]   Transition Report Pursuant to Section 13 or 15(d) of the Securities
      Exchange Act of 1934.
      For the transition period from ...... to ......

                         Commission file number 1-8895

- --------------------------------------------------------------------------------
                     HEALTH CARE PROPERTY INVESTORS, INC.
            (Exact name of registrant as specified in its charter)
- --------------------------------------------------------------------------------

            Maryland                                    33-0091377
(State or other jurisdiction of                     (I.R.S. Employer
 incorporation of organization)                    Identification No.)

                        4675 MacArthur Court, Suite 900
                           Newport Beach, CA  92660
                   (Address of principal executive offices)

                                (949) 221-0600
             (Registrant's telephone number, including area code)
                                        

                               -----------------


     Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days:  Yes [X]  No [_]

     As of April 30, 1999 there were 31,044,176 shares of $1.00 par value common
stock outstanding.

- --------------------------------------------------------------------------------

 
                     HEALTH CARE PROPERTY INVESTORS, INC.

                                     INDEX

                        PART I.  FINANCIAL INFORMATION

                                        
                                                                        PAGE NO.
                                                                        ------- 
Item 1.  Financial Statements:
 
         Condensed Consolidated Balance Sheets
         March 31, 1999 and December 31, 1998...............................   2
 
         Condensed Consolidated Statements of Income
         Three Months Ended March 31, 1999 and 1998.........................   3
 
         Condensed Consolidated Statements of Cash Flows
         Three Months Ended March 31, 1999 and 1998.........................   4
 
         Notes to Condensed Consolidated Financial Statements...............   5
 
Item 2.  Management's Discussion and Analysis of
         Financial Condition and Results of Operations......................  12


                          PART II.  OTHER INFORMATION

Signatures..................................................................  23

                                       1

 
                     Health Care Property Investors, Inc.

                     Condensed Consolidated Balance Sheets
                                        
                                  (Unaudited)

                            (Amounts in thousands)



                                                                              March 31,              December 31,
                                                                                1999                     1998
                                                                             -----------              ----------
                                                                                                 
ASSETS
 
Real Estate Investments
     Buildings and Improvements                                               $1,232,388              $1,143,077
     Accumulated Depreciation                                                   (200,389)               (190,941)
                                                                             -----------              ----------
                                                                               1,031,999                 952,136
     Construction in Progress                                                     25,488                  26,938
     Land                                                                        155,892                 152,045
                                                                             -----------              ----------
                                                                               1,213,379               1,131,119
Loans Receivable                                                                 161,411                 154,363
Investments in and Advances to Joint Ventures                                     53,892                  54,478
Other Assets                                                                      15,380                  12,148
Cash and Cash Equivalents                                                          4,252                   4,504
                                                                             -----------              ----------
 
TOTAL ASSETS                                                                  $1,448,314              $1,356,612
                                                                             -----------              ----------
 
LIABILITIES AND STOCKHOLDERS' EQUITY
 
Bank Notes Payable                                                            $  100,500              $   88,000
Senior Notes Payable                                                             524,141                 499,162
Convertible Subordinated Notes Payable                                           100,000                 100,000
Mortgage Notes Payable                                                            55,219                  21,883
Accounts Payable, Accrued Expenses and Deferred Income                            34,497                  28,758
Minority Interests in Joint Ventures                                              42,910                  23,390
Stockholders' Equity:
  Preferred Stock                                                                187,847                 187,847
  Common Stock                                                                    31,040                  30,987
  Additional Paid-In Capital                                                     434,724                 433,309
  Cumulative Net Income                                                          551,304                 531,926
  Cumulative Dividends                                                          (613,868)               (588,650)
                                                                             -----------              ----------
Total Stockholders' Equity                                                       591,047                 595,419
                                                                             -----------              ----------
 
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                                    $1,448,314              $1,356,612
                                                                              ==========              ==========



     See accompanying Notes to Condensed Consolidated Financial Statements
        and Management's Discussion and Analysis of Financial Condition
                          and Results of Operations.

                                       2

 
                     Health Care Property Investors, Inc.

                  Condensed Consolidated Statements of Income
                                        
                                  (Unaudited)

               (Amounts in thousands, except per share amounts)




                                                                             Three Months
                                                                            Ended March 31,
                                                                     -----------------------------
                                                                      1999                  1998
                                                                     -------               -------
                                                                                       
Revenue
Rental Income                                                        $41,552               $30,288
Tenant Reimbursements                                                  2,051                   496
Interest and Other Income                                              6,018                 5,550
                                                                     -------               -------
                                                                      49,621                36,334
                                                                     -------               -------
 
Expense
Interest Expense                                                      12,360                 7,633
Depreciation/Non Cash Charges                                         10,176                 7,392
Facility Operating Expenses                                            3,751                   797
Other Expenses                                                         2,515                 1,886
                                                                     -------               -------
                                                                      28,802                17,708
                                                                     -------               -------
 
Income From Operations                                                20,819                18,626
    Minority Interests                                                (1,441)               (1,148)
                                                                     -------               -------
Net Income                                                           $19,378               $17,478
 
Dividends to Preferred Stockholders                                    4,109                 1,181
                                                                     -------               -------
 
Net Income Applicable to Common Shares                               $15,269               $16,297
                                                                     =======               =======
 
Basic/Diluted Earnings Per Common Share                              $  0.49               $  0.54
                                                                     =======               =======
 
Weighted Average Shares Outstanding - Basic                           31,021                30,237
                                                                     =======               =======
 
Weighted Average Shares Outstanding - Diluted                         31,119                30,576
                                                                     =======               =======


     See accompanying Notes to Condensed Consolidated Financial Statements
        and Management's Discussion and Analysis of Financial Condition
                          and Results of Operations.

                                       3

 
                     Health Care Property Investors, Inc.

                Condensed Consolidated Statements of Cash Flows
                                        
                                  (Unaudited)

                            (Amounts in thousands)



                                                                              Three Months
                                                                             Ended March 31,
                                                                        -------------------------
                                                                          1999             1998    
                                                                        --------         --------        
                                                                                                
Cash Flows From Operating Activities:                                                                    
 Net Income                                                             $ 19,378         $ 17,478        
 Adjustments to Reconcile Net Income to                                                                  
   Net Cash Provided by Operating Activities:                                                            
   Real Estate Depreciation                                                9,386            6,645        
          Non Cash Charges                                                   790              747        
          Joint Venture Adjustments                                          336             (228)       
 Changes in:                                                                                             
   Operating Assets                                                         (545)            (591)       
   Operating Liabilities                                                   7,089            3,250        
                                                                        --------         --------        
Net Cash Provided By Operating Activities                                 36,434           27,301        
                                                                        --------         --------        
                                                                                                         
Cash Flows From Investing Activities:                                                                    
Acquisition of Real Estate, Net                                          (57,752)         (11,443)       
Advances to Joint Ventures                                                   ---          (18,890)       
Other Investments and Loans                                               (8,529)            (880)       
                                                                        --------         --------        
Net Cash Used In Investing Activities                                    (66,281)         (31,213)       
                                                                        --------         --------        
                                                                                                         
Cash Flows From Financing Activities:                                                                    
Net Change in Bank Notes Payable                                          12,500           15,100        
Repayment of Senior Notes Payable                                            ---          (10,000)       
Issuance of Senior Notes Payable                                          24,938           19,900        
Cash Proceeds from Issuing Common Stock                                       44              ---        
Increase (Decrease) in Minority Interests                                 19,092           (1,000)       
Periodic Payments on Mortgages                                              (545)            (249)       
Dividends Paid                                                           (25,218)         (20,539)       
Other Financing Activities                                                (1,216)            (199)       
                                                                        --------         --------        
Net Cash Provided By Financing Activities                                 29,595            3,013        
                                                                        --------         --------        
                                                                                                         
Net Decrease In Cash And Cash Equivalents                                   (252)            (899)       
                                                                                                         
Cash And Cash Equivalents, Beginning Of Period                             4,504            4,084        
                                                                        --------         --------        
                                                                                                         
Cash And Cash Equivalents, End Of Period                                $  4,252         $  3,185        
                                                                        ========         ========         


     See accompanying Notes to Condensed Consolidated Financial Statements
        and Management's Discussion and Analysis of Financial Condition
                          and Results of Operations.

                                       4

 
                     HEALTH CARE PROPERTY INVESTORS, INC.
             NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                                March 31, 1999

                                  (Unaudited)


(1)  SIGNIFICANT ACCOUNTING POLICIES

     We, the management of Health Care Property Investors, Inc., believe that
the unaudited financial information contained in this report reflects all
adjustments that are necessary to state fairly the financial position, the
results of operations, and cash flows of the Company.  Unless the context
otherwise indicates, the Company or HCPI means Health Care Property Investors,
Inc. and its affiliated subsidiaries and joint ventures.  We presume that users
of this interim financial information have read or have access to the audited
financial statements and Management's Discussion and Analysis of Financial
Condition and Results of Operations for the preceding fiscal year ended December
31, 1998.  Therefore, notes to the financial statements and other disclosures
that would repeat the disclosures contained in our most recent annual report to
security holders have been omitted.  This interim financial information does not
necessarily represent a full year's operations for various reasons including
acquisitions, changes in rents and interest rates, and the timing of debt and
equity financings.

Facility Operations:

     During 1997 and 1998, we purchased 90 - 100 percent ownership interests in
23 medical office buildings ("MOBs") that are operated by independent property
management companies on our behalf.  During the first quarter of 1999, we
purchased 50 percent ownership interest in 14 additional MOBs.  We lease these
facilities to multiple tenants.  Amounts recovered from tenants under such
leases are recorded as Tenant Reimbursements. Expenses related to the operation
of these facilities are recorded as Facility Operating Expenses.

Reclassifications:

     We have made reclassifications, where necessary, for comparative financial
statement presentations.


(2)  MAJOR OPERATORS

     As of March 31, 1999, 88 operators in 43 states operated our properties. In
addition, 232 tenants conducted business in the multi-tenant buildings. Listed
below are our major operators, the number of facilities operated by these
operators, the annualized revenue and the percentage of annualized revenue for
the three months ended March 31, 1999 from these operators and their
subsidiaries:

                                       5

 


 
                                                                 Annualized       Percentage
                                                              Revenue for the       of Our
                                                Number of    Three Months Ended   Annualized
Operators                                       Facilities     March 31, 1999       Revenue
- --------------------------------------------------------------------------------------------
                                                           (Amounts in thousands) 
                                                                         
HealthSouth Corporation ("HealthSouth")               6            $12,335            7%    
Beverly Enterprises Inc. ("Beverly")                 26             11,485            6       
Vencor, Inc. ("Vencor")                              22             11,445            6       
Emeritus Corporation ("Emeritus")                    23             11,288            6       
Columbia/HCA Healthcare Corp. ("Columbia")           12             10,355            6       
Centennial Healthcare Corp. ("Centennial")           18              8,365            4       
Tenet Healthcare Corporation ("Tenet")                2              7,860            4        


     Certain facilities have been subleased to other operators with the original
lessees remaining liable on the leases. The number of facilities, annualized
revenue, and percentages of our total annualized revenue applicable to these
sublessees are not included above. The percentage of our total annualized
revenue on subleased facilities relating to Vencor leases was 3% for the quarter
ended March 31, 1999. As discussed in more detail below, rent obligations under
most Vencor leases are guaranteed by Tenet.

     All these major operators are subject to the informational filing
requirements of the Securities Exchange Act of 1934 and accordingly file
periodic financial statements on Form 10-K and Form 10-Q with the Securities and
Exchange Commission.

Vencor

     On May 1, 1998, Vencor completed a spin-off transaction. As a result, it
became two publicly held entities--Ventas, Inc., a real estate company which
intends to qualify as a REIT, and Vencor, a health care company which at March
31, 1999 leased 38 of HCPI's properties. As of March 31, 1999, 6% of our
annualized revenue was from facilities leased to and operated by Vencor;
additionally, 3% of our revenue is from facilities leased to Vencor which were
subleased and operated by other providers. Both Ventas and Vencor are
responsible for payments due under the Vencor leases, including subleased
facilities. Tenet guarantees the rent payments on most of the Vencor leases (see
discussion under Tenet below).

     According to a press release issued by Vencor, Vencor reported a net loss
of $605.9 million or $8.68 per share for the quarter ended December 31, 1998,
and a net loss from operations of $572.9 million, or $8.39 per share, for the
year ended December 31, 1998. Vencor also announced that it is currently in
discussion with its senior lenders, Ventas and other creditors regarding an
amendment or restructuring of its bank debt, leases and other obligations.
Vencor has reported that as a result of the uncertainties related to Vencor's
ability to amend or restructure its obligations, approximately $461 million of
amounts due under Vencor's bank credit agreement and $300 million of senior
subordinated notes have been classified as current liabilities in its
consolidated balance sheet at December 31, 1998. The report of Vencor's
independent auditors with respect to its condensed consolidated financial
statements for the periods ended December 31, 1998 has an explanatory paragraph
regarding Vencor's ability to continue as a going concern.

                                       6

 
     Vencor also noted in its press release that it also included in current
liabilities approximately $99 million of overpayments to Vencor from the
Medicare program since the inception of the new prospective payment system for
nursing centers on July 1, 1998. Vencor stated that it was informed on April 9,
1999 by the Health Care Financing Administration ("HCFA") that the Medicare
program has made a demand for repayment of approximately $90 million of the
reimbursement overpayments by April 23, 1999. On April 21, 1999, Vencor
announced that it has reached an agreement with HCFA to extend the repayment of
approximately $90 million of Medicare reimbursement overpayments and will now be
obligated to repay the overpayment over 60 monthly installments. Vencor stated
that, "under the agreement, monthly payments of approximately $1.5 million are
due commencing May 8, 1999. After November, the remaining balance of the
overpayments will bear interest at a statutory rate applicable to Medicare
overpayments, as in effect on November 30, 1999. Assuming that the current rate
of 13.75% is in effect on November 30, 1999, the monthly payment amount will be
approximately $2.0 million through March 2004.  If Vencor is delinquent with two
consecutive payments under the repayment plan, the plan will be defaulted and
all subsequent Medicare reimbursement payments to Vencor will be subject to
being withheld." We are unable to predict at this time the effect of any
delinquency of Vencor's Medicare reimbursement payments on its ability to make
its lease payments to us.

     With respect to its obligations under its bank credit agreement and
senior subordinated notes, Vencor has announced that it recently obtained a
waiver of certain financial covenants through May 28, 1999 from the lenders
under its credit facility, and that it would not pay the $14.8 million interest
payment due May 3, 1999 on its senior subordinated notes, giving the holders of
the senior subordinated notes the right to accelerate those obligations upon
expiration of a 30 day grace period, and applicable notice periods.  Standard &
Poor's downgraded the ratings on Vencor's senior subordinated debt to D
(removing such debt from credit watch) on May 3, 1999 and Moody's downgraded its
ratings on such senior subordinated debt to C on May 5, 1999.  On May 10, 1999
Vencor and Ventas announced that Vencor had failed to pay the monthly rent for
May 1999 to Ventas and that the two parties had negotiated an extension of the
rent to June 6, 1999, and an extension of the standstill agreement between them
to June 11, 1999.

     In its Annual Report on Form 10-K for the year ended December 31, 1998,
Vencor made a number of cautionary statements regarding its financial condition
and results of operations, and indicated that in the event of certain
circumstances relating to actions by its creditors or its ability to consummate
an alternative financial structure, it "likely would be forced to file for
protection under Chapter 11 of the Bankruptcy Code." If Vencor were to file for
bankruptcy protection, it will have an obligation to pay rent to us during the
pendency of the proceeding. However, Vencor will have the right to assume or
reject its leases with us. If Vencor assumes a lease it must do so pursuant to
the original contract terms, must cure all pre-petition and post-petition
defaults under the lease and provide adequate assurances of future performance.
If Vencor rejects a lease, it may stop paying rent and we may lease the property
to another lessee. However, we cannot assure you, in the event of a Vencor
bankruptcy, that we would be able to recover amounts due under our leases with
Vencor, that we would be able to promptly recover the premises or lease the
property to another lessee or that the rent we would receive from another

                                       7

 
lessee would equal amounts due under the Vencor leases. The rents under all but
three of the Vencor leases are guaranteed by Tenet, and on some leases we may
seek direct payment by sublessees of Vencor, which may reduce the risk to us of
a Vencor bankruptcy. However, we cannot assure you that a bankruptcy filing of
Vencor would not have a material adverse effect on our funds from operations or
the market value of our common stock.

Tenet

     Tenet is one of the nation's largest health care services companies,
providing a broad range of services through the ownership and management of
health care facilities. Tenet has historically guaranteed Vencor's leases.
However, during 1997 we reached an agreement with Tenet whereby Tenet agreed to
forbear or waive some renewal and purchase options and related rights of first
refusal on facilities leased to Vencor. As part of that same agreement, Tenet
will only guarantee the rent payments on the Vencor leases until the end of
their base term. During the year ended December 31, 1998, 14 Vencor leases
previously guaranteed by Tenet expired. Eleven of the 14 were leased to third
parties and three were retained by Vencor but are no longer guaranteed by Tenet.
The remaining 36 guaranteed leases all expire within three years.


(3)  REAL ESTATE INVESTMENTS

     During the first quarter of 1999, we acquired 14 MOBs through the purchase
of a 50% managing partner interest in a company in which the non-managing
partner purchased 593,249 non-managing member units.  These units which are
recorded under Minority Interest in Joint Ventures are convertible into HCPI
stock on a one-for-one basis beginning in January, 2000.


(4)  STOCKHOLDERS' EQUITY

     The following tabulation is a summary of the activity for the Stockholders'
Equity account for the three months ended March 31, 1999 (amounts in thousands):



                                   Preferred Stock                Common Stock
                                 ------------------    ---------------------------------
                                                                     Par      Additional                                  Total
                                 Number of             Number of    Value       Paid In    Cumulative    Cumulative    Stockholders'

                                   Shares    Amount      Shares     Amount      Capital    Net Income    Dividends        Equity
- ------------------------------------------------------------------------------------------------------------------------------------

                                                                                                
Balance,
    December 31, 1998               7,785   $187,847     30,987     $30,987     $433,309     $531,926    $(588,650)       $595,419
Issuance of Common Stock, Net                                53          53        1,415                                     1,468
Net Income                                                                                     19,378                       19,378
Dividends Paid  Preferred
 Shares                                                                                                     (4,109)         (4,109)
Dividends Paid  Common Shares                                                                              (21,109)        (21,109)
- ------------------------------------------------------------------------------------------------------------------------------------

Balance,
   March 31, 1999                   7,785   $187,847     31,040     $31,040     $434,724     $551,304    $(613,868)       $591,047
- ------------------------------------------------------------------------------------------------------------------------------------



                                       8

 
(5)  EARNINGS PER COMMON SHARE

     The Company adopted Statement of Financial Accounting Standards No. 128,
Earnings Per Share, effective December 15, 1997.  As a result, both basic and
diluted earnings per common share are presented for each of the quarters ended
March 31, 1999 and 1998.  Prior to 1997, only basic earnings per common share
was disclosed.  Basic earnings per common share is computed by dividing net
income applicable to common shares by the weighted average number

of shares of common stock outstanding during the period.  Diluted earnings per
common share is calculated including the effect of dilutive securities. Options
to purchase shares of common stock that had an exercise price in excess of the
average market price of the common stock during the period were not included
because they are not dilutive.

(Amounts in thousands except per share amounts)



                                                 For the Three Months Ended    
                                             ---------------------------------         
                                                                     Per Share         
March 31, 1999                               Income      Shares        Amount          
- --------------------------------------       ------      ------      ---------         
                                                                           
Basic Earnings Per Common Share:                                                       
Net Income Applicable to Common Shares       $15,269     31,021         $0.49          
                                                                     ---------         
                                                                                       
Dilutive Options                                 ---         98                        
                                             -------     ------                        
                                                                                       
Diluted Earnings Per Common Share:                                                     
Net Income Applicable to Common                                                        
 Shares Plus Assumed Conversions              15,269     31,119         $0.49          
                                                                     ---------          
 
                                                 For the Three Months Ended    
                                             ---------------------------------         
                                                                     Per Share         
March 31, 1998                               Income      Shares        Amount          
- --------------------------------------       ------      ------      ---------         
Basic Earnings Per Common Share:
Net Income Applicable to Common Shares       $16,297     30,237         $0.54
                                                                     ---------         
 
Non-Managing Member Units                         86        121
Dilutive Options                                 ---        218
                                             ------      ------       
 
Diluted Earnings Per Common Share:
Net Income Applicable to Common     
  Shares Plus Assumed Conversions            16,383      30,576         $0.54
                                             ------      ------      ---------          



(6)  FUNDS FROM OPERATIONS

     Effective in 1998, the Statement of Financial Accounting Standards No. 131,
Disclosures about Segments of an Enterprise, requires that we report information
about our operations on the same basis that is used internally to measure
performance.

     We believe that Funds From Operations ("FFO") is our most important
supplemental measure of operating performance.  Because the historical cost
accounting convention used for real estate assets requires straight-line
depreciation (except on land) such accounting presentation implies that the
value of real estate assets diminishes predictably over time.  Because real
estate values instead have historically risen and fallen with market conditions,
presentations of operating results for a real estate investment trust that uses
historical cost accounting for depreciation could be less informative.  The term
FFO was designed by the real estate investment trust industry to address this
problem.

                                       9

 
     The Company adopted the definition of FFO prescribed by the National
Association of Real Estate Investment Trusts ("NAREIT").  FFO is defined as net
income applicable to common shares (computed in accordance with generally
accepted accounting principles), excluding gains (or losses) from debt
restructuring and sales of property, plus real estate depreciation and real
estate related amortization, and after adjustments for unconsolidated
partnerships and joint ventures. Adjustments for unconsolidated partnerships and
joint ventures are calculated to reflect FFO on the same basis.

     FFO does not represent cash generated from operating activities in
accordance with generally accepted accounting principles, is not necessarily
indicative of cash available to fund cash needs and should not be considered as
an alternative to net income.  FFO, as defined by the Company, may not be
comparable to similarly entitled items reported by other real estate investment
trusts that do not define it exactly as the NAREIT definition.

     Below are summaries of the calculation of FFO and FFO per share of common
stock (all amounts in thousands except per share amounts):



                                                           Three Months
                                                          Ended March 31,
                                                       --------------------
                                                         1999         1998
                                                       -------      -------
                                                              
Net Income Applicable to Common Shares                 $15,269      $16,297
Real Estate Depreciation and Amortization                9,386        6,645
Joint Venture Adjustments                                  336         (228)
                                                       -------      -------
 
Funds From Operations                                  $24,991      $22,714
                                                       -------      -------


(7)  COMMITMENTS

     As of  April 27, 1999, the Company has acquired real estate properties and
has outstanding commitments to fund development of facilities on those
properties of approximately $33,000,000.

     The Company is also committed to acquire approximately $54,000,000 of
existing health care real estate. The Company expects that a significant portion
of these commitments will be funded; however, experience suggests that some
committed transactions will not close. The letters of intent representing such
commitments permit either party to elect not to go forward with the transaction
under various circumstances.  We may not close committed transactions for
various reasons including unsatisfied pre-closing conditions, competitive
financing sources, final negotiation differences or the operator's inability to
obtain required internal or governmental approvals.

                                       10

 
(8)  NEW PRONOUNCEMENTS

     In June 1998, the Financial Accounting Standards Board issued Statement of
Financial Accounting Standards No. 133, Accounting for Derivative Instruments
and Hedging Activities. The Statement establishes accounting and reporting
standards requiring that every derivative instrument (including certain
derivative instruments embedded in other contracts) be recorded in the balance
sheet as either an asset or liability measured at its fair value. The Statement
requires that changes in the derivative's fair value be recognized currently in
earnings unless specific hedge accounting criteria are met. Statement 133 is
effective for fiscal years beginning after June 15, 1999, although earlier
implementation is allowed.

     We have not yet quantified the impact of adopting Statement 133 on our
financial statements and have not determined the timing or method of our
adoption of Statement 133. However, the effect is not expected to be material.


(9)  SUBSEQUENT EVENTS

     On April 20, 1999 the Board of Directors declared a quarterly dividend of
$0.69 per common share payable on May 20, 1999, to shareholders of record on the
close of business on May  3, 1999.

     The Board of Directors also declared a cash dividend of $0.492188 per share
on its Series A cumulative preferred stock and $0.54375 per share on its Series
B cumulative preferred stock.  These dividends will be paid on June 30, 1999 to
shareholders of record as of the close of business on June 15, 1999.

     On May 3, 1999, the Company issued 1,000,000 shares of Common Stock which
generated net proceeds of approximately $29,600,000 (net of underwriters'
discount and other offering expenses).  The proceeds were used to pay off short-
term bank debt.

                                       11

 
                     HEALTH CARE PROPERTY INVESTORS, INC.
          MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                           AND RESULTS OF OPERATIONS


GENERAL

     The Company is in the business of acquiring health care facilities that we
lease on a long-term basis to health care providers.  On a more limited basis,
we have provided mortgage financing on health care facilities. As of March 31,
1999, the Company's portfolio of properties, including equity investments,
consisted of 347 facilities located in 43 states.  These facilities are
comprised of 157 long-term care facilities, 85 congregate care and assisted
living facilities, 41 physician group practice clinics, 49 medical office
buildings, eight acute care hospitals, six freestanding rehabilitation
facilities and one psychiatric care facility. The gross acquisition price of the
properties, which includes joint venture acquisitions, was approximately
$1,640,000,000 at March 31, 1999.

     We have commitments to purchase and construct health care facilities
totaling approximately $87,000,000 for funding during 1999 and 2000.  We expect
that a significant portion of these commitments will be funded but that a
portion may not be funded  (see Note (7) to the Condensed Consolidated Financial
Statements).

RESULTS OF OPERATIONS

     Net Income applicable to common shares for the three months ended March 31,
1999 totaled $15,269,000 or $0.49 of diluted earnings per share on revenue of
$49,621,000.  This compares to $16,297,000 or $0.54 of diluted earnings per
share on revenue of $36,334,000, for the same period in 1998.  The decrease in
Net Income is attributable to higher interest expense and depreciation/non-cash
charges offset by higher Rental and Interest and Other Income.

     Rental Income for the three months ended March 31, 1999 increased by
$11,264,000 to $41,552,000 as compared to the same period in the prior year.
The majority of the increase in Rental Income was generated by new investments
made during 1998 and the first quarter of 1999. Interest and Other Income for
the three months ended March 31, 1999 increased $468,000 to $6,018,000.  The
increase was primarily from growth in the lending portfolio.

     Interest Expense for the three months ended March 31, 1999 increased by
$4,727,000 to $12,360,000.  The increase is primarily the result of an increase
in short-term borrowings used to fund the acquisitions made during 1998 and the
first quarter of 1999, interest related to the MOPPRS senior debt issuance
during June 1998 and interest on mortgage loans assumed on the first quarter
acquisition of 14 MOBs.  The increase in Depreciation/Non Cash Charges for the
three months ended March 31, 1999 of $2,784,000 to $10,176,000 is the direct
result of the new investments made during 1997, 1998 and 1999.  Facility
Operating Expenses for the three months ended March 31, 1999 increased
$2,954,000 to $3,751,000.  The increase is due to the operating expenses on the
newly acquired MOBs and clinics.  These facilities are operated by property
management companies on behalf of the Company.

                                       12

 
     We believe that FFO is an important supplemental measure of operating
performance.  (See Note (6) to the Condensed Consolidated Financial Statements.)

     FFO for the three months ended March 31, 1999 increased $2,277,000 to
$24,991,000 as compared to the same period in the prior year.  The increase is
attributable to increases in Rental Income, and Interest and Other Income, as
offset by increases in Interest Expense and Facility Operating Expenses, which
are discussed above.

     FFO does not represent cash generated from operating activities in
accordance with generally accepted accounting principles, is not necessarily
indicative of cash available to fund cash needs and should not be considered as
an alternative to net income.  FFO, as we defined it, may not be comparable to
similarly entitled items reported by other real estate investment trusts that do
not use the NAREIT definition.

LIQUIDITY AND CAPITAL RESOURCES

     The Company has financed acquisitions through the sale of common and
preferred stock, issuance of long-term debt, assumption of mortgage debt, use of
short-term bank lines and through internally generated cash flows.  Facilities
under construction are generally financed by means of cash on hand or short-term
borrowings under our existing bank lines. At the completion of construction and
commencement of the lease, short-term borrowings used in the construction phase
are generally refinanced with new long-term debt, including Medium Term Notes
("MTNs"), or with equity offerings.

MTN FINANCINGS
- ---------------

     The following table summarizes the MTN financing activities during 1998 and
1999:



                                                             Amount
Date                     Maturity      Coupon Rate      Issued/(Redeemed)
- -------------------    -----------    -------------    -------------------
                                              
February 1998                 ---         9.88%               $(10,000,000)
March 1998                 5 years        6.66%                 20,000,000
April-November 1998           ---      6.10%-9.70%             (17,500,000)
November 1998            3-8 years     7.30%-7.88%              28,000,000
February 1999              5 years        6.92%                 25,000,000
April 1999                 5 years     7.00%-7.48%              37,000,000



SENIOR DEBT OFFERINGS
- ---------------------

     During June 1998, the Company issued $200 million of 6.875% MandatOry Par
Put Remarketed Securities ("MOPPRS") due June 8, 2015 which are subject to
mandatory tender on June 8, 2005.  We  received total proceeds of approximately
$203,000,000 (including the present value of a put option associated with the
debt) which was used to repay borrowings under our revolving lines of credit.
The weighted average cost of the debt including the amortization of the option
and offering expenses is 6.77%.  The MOPPRS are senior, unsecured obligations of
the Company.

                                       13

 
EQUITY OFFERINGS
- ----------------

     Since September 1997, HCPI has completed five equity offerings, summarized
in the table below:



                                                           Shares         Equity                                
      Date                      Issuance                   Issued         Raised         Net Proceeds
- --------------     ---------------------------------     ---------     -------------     ------------
                                                                             
September 1997     7-7/8% Series A Cumulative            2,400,000      $ 60,000,000     $ 57,810,000
                   Redeemable Preferred Stock                                                                
                                                                                                             
December 1997      Common Stock at $38.3125/share        1,437,500      $ 55,000,000     $ 51,935,000
                                                                                                             
April 1998         Common Stock at $33.2217/share to       698,752      $ 23,200,000     $ 23,000,000
                   a Unit Investment Trust                                                                   
                                                                                                             
September 1998     8.70% Series B Cumulative             5,385,000      $135,000,000     $130,000,000
                   Redeemable Preferred Stock                                                                
                                                                                                             
May 1999           Common Stock at $31.4375/share        1,000,000      $ 31,400,000     $ 29,600,000


     HCPI used the net proceeds from the equity offerings to pay down or pay off
short-term borrowings under its revolving lines of credit.  HCPI invested any
excess funds in short-term investments until they were needed for acquisitions
or development.

     At March 31, 1999, stockholders' equity totaled $591,047,000 and the debt
to equity ratio was 1.32 to 1.00.  For the three months ended March 31, 1999,
FFO (before interest expense) covered Interest Expense 3.02 to 1.00.

AVAILABLE FINANCING SOURCES
- ---------------------------

     During June 1998, the Company registered $600,000,000 of debt and equity
securities under a shelf registration statement filed with the Securities and
Exchange Commission. As of May 10, 1999 we had approximately $397,000,000
remaining on shelf filings for future financings. Of that amount, we had
approximately $110,000,000 available under our MTN senior debt programs. We may
issue securities under our universal shelf, including under our MTN program, up
to these amounts from time to time in the future based on Company needs and then
existing market conditions. On September 30, 1998, we renegotiated our lines of
credit with a group of seven banks. We have two revolving lines of credit, one
for $135,000,000 that expires on September 30, 2003 and one for $45,000,000 that
expires on September 30, 1999. As of May 10, 1999, the Company had $108,000,000
available on these lines of credit. Since 1986 the debt rating agencies have
rated our Senior Notes and Convertible Subordinated Notes investment grade.
Current ratings are as follows:



                             Moody's    Standard & Poor's    Duff & Phelps
                             -------    -----------------    -------------
                                                      
Senior Notes                  Baa1            BBB+                 BBB+
Convertible
 Subordinated Notes           Baa2            BBB                  BBB


      On May 13, 1999, we were informed by Duff and Phelps that they are
      changing the senior note rating for the Company from A to BBB+, and the
      convertible subordinate note rating from BBB+ to BBB.

                                       14

 
     Since inception in May 1985, the Company has recorded approximately
$715,460,000 in cumulative FFO.  Of this amount, we have distributed a total of
$599,981,000 to stockholders as dividends on common stock.  We have retained the
balance of $115,479,000 and used it as an additional source of capital.

     At March 31, 1999, the Company held approximately $41,000,000 in
irrevocable letters of credit from commercial banks to secure the obligations of
many lessees' lease and borrowers' loan obligations.  We may draw upon the
letters of credit if there are any defaults under the leases and/or loans.
Amounts available under letters of credit could change based upon facility
operating conditions and other factors and such changes may be material.

     We paid the first quarter 1999 dividend of $0.68 per common share or
$21,109,000 in the aggregate on February 19, 1999.  Total dividends paid during
the three months ended March 31, 1999, as a percentage of FFO was 84%.  The
Company declared a second quarter dividend of $0.69 per common share or
approximately $22,110,000 in the aggregate, payable on May 20, 1999.

FACILITY ROLLOVERS
- ------------------

  HCPI has concluded a significant number of "facility rollover" transactions in
1995, 1996, 1997 and 1998 on properties that have been under long-term leases
and mortgages. Facility rollover transactions principally include lease renewals
and renegotiations, exchanges, sales of properties, and, to a lesser extent,
payoffs on mortgage receivables.  The annualized impact was to increase FFO in
1995 by $900,000 and decrease FFO in each of the years 1996 through 1998 by
$1,200,000, $1,600,000 and $3,100,000, respectively.  Total rollovers were 20
facilities, 20 facilities, 12 facilities and 44 facilities in each of the years
1995 - 1998.

     For the year ending December 31, 1999, HCPI has 17 facilities that are
subject to lease expiration and mortgage maturities.  These facilities currently
represent approximately 7% of annualized revenues.  For the year ended December
31, 2000, HCPI has seven facilities that are subject to lease expiration and
mortgage maturities.  These facilities currently represent approximately 6% of
annualized revenue.

     During 1997, HCPI reached agreement with Tenet (the holder of substantially
all the option rights of the Vencor leases) whereby Tenet agreed to waive
renewal and purchase options, and related rights of first refusal, on up to 51
facilities. As part of these agreements, HCPI has the right to continue to own
the facilities.  HCPI paid Tenet $5,000,000 in cash, accelerated the purchase
option on two acute care hospitals leased to Tenet, and reduced Tenet's
guarantees on the facilities leased to Vencor.  Leases on 20 of those 51
facilities had expiration dates through December 31, 2000.  HCPI has increased
rents on five of the facilities with leases that have already expired during
1998, and believes it will be able to increase rents on other facilities whose
lease terms expire through 2001. However, there can be no assurance that HCPI
will be able to realize any increased rents on future rollovers. HCPI has
completed certain facility rollovers earlier than the scheduled lease
expirations or mortgage maturities and will continue to pursue such
opportunities where it is advantageous to do so.

                                       15

 
     Management believes that HCPI's liquidity and sources of capital are
adequate to finance its operations as well as its future investments in
additional facilities.

YEAR 2000 ISSUE

     The Year 2000 issue is the result of widely used computer programs that
identify the year by two digits, rather than by four.  It is believed that
continued use of these programs may result in widespread computer-generated
malfunctions and miscalculations beginning in the year 2000, when the digits
"00" are interpreted as "1900."  Those miscalculations could cause disruption of
operations including the temporary inability to process transactions such as
invoices for payment.  Those computer programs that identify the year based on
all four digits are considered "Year 2000 compliant."  The statements in the
following section include "Year 2000 readiness disclosure" within the meaning of
the Year 2000 Information and Readiness Disclosure Act of 1998.

Status of Year 2000 Issues with HCPI's Own Information Technology Systems and
Non-IT Systems

     HCPI's primary use of information technology ("IT") is in its financial
accounting systems, billing and collection systems and other information
management software.  HCPI's operations are conducted out of its corporate
offices in Newport Beach, California where it uses and is exposed to non-IT
systems such as those contained in embedded micro-processors in telephone and
voicemail systems, elevators, heating, ventilation and air conditioning (HVAC)
systems, lighting timers, security systems, and other property operational
control systems.

     HCPI believes that it does not have significant exposure to Year 2000
issues with respect to its own accounting and information software systems or
with respect to non-IT systems contained in embedded chips used in its corporate
offices.  HCPI has been working with its computer consultants to test and
continually upgrade its management information systems and has reasonable
assurance from its vendors and outside computer consultants that HCPI's
financial and other information systems are Year 2000 compliant.  The cost to
bring the management information systems into Year 2000 compliance has not been
material.  While any disruption in services at HCPI's corporate offices due to
failure of non-IT systems may be inconvenient and disruptive to normal day-to-
day activities, it is not expected to have a materially adverse effect on HCPI's
financial performance or operations.

Exposure to Third Parties' Year 2000 Issues

     Because HCPI believes its own accounting and information systems are
substantially Year 2000 compliant, HCPI does not feel there will be material
disruption to its transaction processing on January 1, 2000.  However, HCPI
depends upon its tenants for rents and cash flows, its financial institutions
for availability of working capital and capital markets financing and its
transfer agent to maintain and track investor information.  If HCPI's primary
lessees and mortgagors are not Year 2000 compliant, or if they face disruptions
in their cash flows due to Year 2000 issues,  HCPI could face significant
temporary disruptions in its cash flows after that date.  These disruptions
could be exacerbated if the commercial banks that process HCPI's cash receipts
and disbursements and its lending institutions are not Year 2000 compliant.

                                       16

 
Furthermore, to the extent there are broad market disruptions as a result of
widespread Year 2000 issues, HCPI's access to the capital markets to raise cash
for investing activity could be impaired.

     To address this concern, during the second quarter of 1998, HCPI commenced
a written survey of all of its major tenants, Bank of New York in its capacity
as agent under HCPI's credit facilities, and as common stock Transfer Agent and
Trustee under its senior debt indenture, each other lender under HCPI's credit
facility, its primary investment banker for HCPI's capital raising activities,
and HCPI's independent public accountants and primary outside legal counsel.
The survey asked each respondent to assess its exposure to Year 2000 issues and
asked what preparations each has made to deal with the Year 2000 issue with
respect to both information technology and non-IT systems.  In addition HCPI
asked each respondent to inform it about their exposure to third party vendors,
customers and payers who may not be Year 2000 compliant.

     Through this process HCPI has been informed in writing by approximately 95%
of those surveyed that they believe that they have computer systems that are or
will be Year 2000 compliant by the end of 1999.  All continue to assess their
own exposure to the issue.  However neither HCPI nor its lessees and mortgagors
can be assured that the federal and state governments, upon which they rely for
Medicare and Medicaid revenue, will be in compliance in a timely manner.

     HCPI is in the process of assessing its exposure to failures of embedded
microprocessors contained in elevators, electrical and HVAC systems, security
systems and the breakdown of other non-IT systems due to the Year 2000 issue at
the properties operated by its tenants.  Under a significant portion of its
leases, HCPI is not responsible for the cost to repair such items and is
indemnified by the tenants for losses caused by their operations on the
property.  For the medical office buildings where HCPI may be responsible for
repairing such items, HCPI does not believe that the costs of repair will be
material to HCPI and any such costs will be expensed as incurred.

Risks to HCPI  of Year 2000 Issues

     HCPI's exposure to the Year 2000 issue depends primarily on the readiness
of its significant tenants and commercial banks, who in turn, are dependent upon
suppliers, payers and other external parties, all of which is outside HCPI's
control.  HCPI believes the most reasonably likely worst case scenario faced by
HCPI as a result of the Year 2000 issue is the possibility that reimbursement
delays caused by a failure of federal and state welfare programs responsible for
Medicare and Medicaid could adversely affect its tenants' cash flow, resulting
in their temporary inability to meet their obligations under its leases.
Depending upon the severity of any reimbursement delays and the financial
strength of any particular operator, the operations of HCPI's tenants could be
materially adversely affected, which in turn could have a material adverse
effect on HCPI's results of operations.

                                       17

 
     In September 1998, the General Accounting Office reported that the Health
Care Financing Administration ("HCFA"), which runs Medicare, is behind schedule
in taking steps to deal with the Year 2000 issue and that it is highly unlikely
that all of the Medicare systems will be compliant in time to ensure the
delivery of uninterrupted benefits and services into the year 2000.  The General
Accounting Office also reported in November 1998 that, based upon its survey of
the states, the District of Columbia and three territories, less than 16% of the
automated systems used by state and local government to administer Medicaid are
reported to be Year 2000 compliant.  HCPI does not know at this time whether
there will in fact be a disruption of Medicare or Medicaid reimbursements to its
lessees and mortgagors and HCPI is therefore unable to determine at this time
whether the Year 2000 issue will have a material adverse effect on HCPI or its
future operations.

Contingency Plans

     If there are severe disruptions in HCPI's cash flow as a result of
disruptions in its tenants' or mortgagors' cash flow, HCPI may be forced to slow
its investment activity, or seek additional liquidity from its lenders.

     Readers are cautioned that most of the statements contained in the "Year
2000 Issue" paragraphs are forward looking and should be read in conjunction
with HCPI's disclosures under the heading "Cautionary Language Regarding Forward
Looking Statements" set forth below.

Cautionary Language Regarding Forward Looking Statements

     Statements in this Annual Report that are not historical factual statements
are "forward looking statements" within the meaning of the Private Securities
Litigation Reform Act of 1995.  The statements include, among other things,
statements regarding the intent, belief or expectations of HCPI and its officers
and can be identified by the use of terminology such as "may", "will", "expect",
"believe", "intend", "plan", "estimate", "should" and other comparable terms or
the negative thereof.  In addition, HCPI, through its senior management, from
time to time makes forward looking oral and written public statements concerning
HCPI's expected future operations and other developments.  Shareholders and
investors are cautioned that, while forward looking statements reflect HCPI's
good faith beliefs and best judgment based upon current information, they are
not guarantees of future performance and are subject to known and unknown risks
and uncertainties.  Actual results may differ materially from the expectations
contained in the forward looking statements as a result of various factors.
Such factors include:

 (a)  Legislative, regulatory, or other changes in the healthcare industry at
      the local, state or federal level which increase the costs of or otherwise
      affect the operations of HCPI's lessees;
 (b)  Changes in the reimbursement available to HCPI's lessees and mortgagors by
      governmental or private payors, including changes in Medicare and Medicaid
      payment levels and the availability and cost of third party insurance
      coverage;
 (c)  Competition for lessees and mortgagors, including with respect to new
      leases and mortgages and the renewal or rollover of existing leases;
 (d)  Competition for the acquisition and financing of health care facilities;

                                       18

 
 (e)  The ability of HCPI's lessees and mortgagors to operate HCPI's properties
      in a manner sufficient to maintain or increase revenues and to generate
      sufficient income to make rent and loan payments;
 (f)  Changes in national or regional economic conditions, including changes in
      interest rates and the availability and cost of capital to HCPI; and
 (g)  General uncertainty inherent in the Year 2000 issue, particularly the
      uncertainty of the Year 2000 readiness of third parties who are material
      to HCPI's business, such as public or private healthcare reimbursers, over
      whom HCPI has no control with the result that HCPI cannot ensure its
      ability to timely and cost-effectively avert or resolve problems
      associated with the Year 2000 issue that may affect its operations and
      business.

DISCLOSURES ABOUT MARKET RISK

  HCPI is exposed to market risks related to fluctuations in interest rates on
its mortgage loans receivable and on its debt instruments.  The following
discussion and table presented below are provided to address  the  risks
associated with potential changes in HCPI's interest rate environment.

  HCPI provides mortgage loans to operators of healthcare facilities in the
normal course  of  business. All of the mortgage loans receivable have fixed
interest rates or interest rates with periodic fixed increases.  Therefore, the
mortgage loans receivable are all considered to be fixed rate loans, and the
current interest rate (the lowest rate) is used in the computation of market
risk provided in the table below if material.

  HCPI generally borrows on its short-term bank lines of credit to complete
acquisition transactions.  These borrowings are then repaid using proceeds from
subsequent long-term debt and equity offerings.  HCPI may also assume mortgage
notes payable already in place as part of an acquisition transaction.  Currently
HCPI has two mortgage notes payable with variable interest rates and the
remaining mortgage notes payable have fixed interest rates or interest rates
with fixed periodic increases.  HCPI's senior notes and convertible debt are at
fixed rates.  The variable rate loans are at interest rates at or below the
current prime rate of 7.75%, and fluctuations are tied to the prime rate or to a
rate currently below the prime rate.

  Fluctuation in the interest rate environment will not impact HCPI's future
earnings and cash flows on its fixed rate debt until that debt matures and must
be replaced or refinanced. Interest rate changes will affect the fair value of
the fixed rate instruments. Conversely, changes in interest rates on variable
rate debt would change the future earnings and cash flows of HCPI, but not
affect the fair value on those instruments. Assuming a one percentage point
increase in the interest rate related to the variable rate debt including the
mortgage notes payable and the bank lines of credit, and assuming no change in
the outstanding balance as of the quarter ended March 31, 1999, interest expense
for the coming year would increase by approximately $1,207,000. Approximately
50% of the increase in interest expense related to the bank lines of credit, or
$500,000, would be capitalized into construction projects.

                                       19

 
  The principal amount and the average interest rates for the mortgage loans
receivable and debt categorized by the final maturity dates are presented in the
table below. Certain of the mortgage loans receivable and certain of the debt
securities, excluding the convertible debentures, require periodic principal
payments prior to the final maturity date. The fair value estimates for the
mortgage loans receivable are based on the estimates of management and on rates
currently prevailing for comparable loans. The fair market value estimates for
debt securities are based on discounting future cash flows utilizing current
rates offered to HCPI for debt of the same type and remaining maturity.




                                                                           Maturity                                                
                                         ----------------------------------------------------------------------------     ---------
                                                                                                                            Fair   
                                           1999       2000       2001        2002       2003    Thereafter      Total       Value  
                                         ----------------------------------------------------------------------------     ---------
                                                                                                        
ASSETS                                                                                                                             
  Mortgage Loans Receivable                                   $17,565     $ 2,502                 $126,413   $146,480      $156,000
                                                                13.03%      10.17%                    9.79%     10.19%             
LIABILITIES                                                                                                                        
Variable Rate Debt:                                                                                                                
                                                                                                                                   
     Bank Notes Payable                                                                            100,500    100,500       100,500
       Weighted Average Interest Rate                                                                 5.35%      5.35%             
                                                                                                                                   
     Mortgage Notes Payable              13,639                 2,593       1,579                    4,968     22,779        21,280
       Weighted Average Interest Rate      7.75%                 7.75%       5.87%                    5.75%      7.21%             
                                                                                                                                   
Fixed Rate Debt:                                                                                                                   
                                                                                                                                   
     Senior Notes Payable                15,000     10,000     13,000      17,000     31,000       438,142    524,142       500,000
       Weighted Average Interest Rate      9.98%      8.87%      7.88%       8.40%      7.09%         6.85%      7.10%             
                                                                                                                                   
     Convertible Subordinated 
      Notes Payable                                100,000                                                    100,000       100,773
       Weighted Average Interest Rate                 6.00%                                                      6.00%             
                                                                                                                                   
     Mortgage Notes Payable                (103)       103                    555                   31,886     32,441        34,350
       Weighted Average Interest Rate      8.91%      9.00%                  9.00%                    8.57%      8.60%              



     HCPI does not believe that the future market rate risks related to the
above securities will have a material impact on HCPI or the results of its
future operations.  Readers are cautioned that most of the statements contained
in these "Disclosures about Market Risk" paragraphs are forward looking and
should be read in conjunction with HCPI's disclosures under the heading
"Cautionary Language Regarding Forward Looking Statements" set forth above.

                                       20

 
                          PART II.  OTHER INFORMATION

Item 2.  Amendments to Bylaws
         --------------------
 
     On April 28, 1999, the Board of Directors of the Company amended the
Amended and Restated Bylaws of the Company in order to (i) establish a 31 day
period for the annual meeting of stockholders in compliance with the
requirements of Maryland corporate law, (ii) raise the percentage of
stockholders required to request a special meeting of the stockholders from 25%
to 50%, (iii) allow the committees of the Board of Directors to consist of one
or more directors instead of two or more, and (iv) provide that upon any default
in the payment of dividends on any class or series of preferred stock or any
other event which would allow the holders of such preferred stock to elect
additional directors, the number of directors may be increased by the number of
additional directors to be elected by such holders, for so long as such holders
have the right to elect additional directors.  A copy of the Second Amended and
Restated Bylaws of the Company is attached as an exhibit to this quarterly
report on Form 10-Q.

Amendment to Rights Plan
- ------------------------

     On July 5, 1990 the Board of Directors of the Company declared a dividend
distribution of one right (each, a "Right") for each outstanding share of Common
Stock of the Company to stockholders of record at the close of business on July
30, 1990 and entered into a Rights Agreement. When exercisable, each Right
entitles the registered holder to purchase from the Company one share of the
Company's Common Stock at a price of $47.50 per share, subject to adjustment.
Initially, the Rights will be attached to all outstanding shares of Common
Stock, and no separate Rights Certificates will be distributed. The Board also
authorized the issuance of one Right with respect to each share of Common Stock
that shall become outstanding between July 30, 1990 and the earliest of the
Distribution Date, the Redemption Date and the Final Expiration Date (all as
defined in the Rights Agreement). Each share of Common Stock offered hereby will
have upon issuance one Right attached.

     The Rights will become exercisable and will detach from the Common Stock
upon the earlier of (i) the tenth day after the public announcement that any
person or group has acquired beneficial ownership of 15% or more of the
Company's Common Stock, or (ii) the tenth day after any person or group
commences, or announces an intention to commence, a tender or exchange offer
which, if consummated, would result in the beneficial ownership by a person or
group of 30% or more of the Company's Common Stock (the earlier of (i) and (ii)
being the "Distribution Date"). If such person or group acquires beneficial
ownership of 15% or more of the Company's Common Stock (except pursuant to
certain cash tender offers for all outstanding Common Stock approved by the
Board of Directors) or if the Company is the surviving corporation in a merger
and its Common Stock is not changed or exchanged, each Right will entitle the
holder to purchase, at the Right's then current exercise price, that number of
shares of the Company's Common Stock having a market value equal to twice the
exercise price. Similarly, if after the Rights become exercisable, the Company
merges or consolidates with, or sells 50% or more of its assets or earning power
to, another person, each Right will then entitle the holder to purchase, at the
Right's then current exercise price, that number of shares of the stock of the
acquiring company which at the time of such transaction would have a market
value equal to twice the exercise price.

                                       21

 
     The Rights may be redeemed in whole, but not in part, at a price of $0.01
per Right by the Board of Directors at any time until ten days following the
public announcement that a person or group has acquired beneficial ownership of
15% or more of the Company's outstanding Common Stock. Under the original Rights
Agreement, the Board of Directors could, under certain circumstances, extend the
period during which the Rights are redeemable or postpone the Distribution Date.

     In January 1999 we amended our Rights Agreement to provide that Rights
issued under the Rights Agreement may be redeemed, at a price of $.005 per
Rights, until the time that a person or group has acquired beneficial ownership
of 15% or more or our outstanding common stock.  As a result of the amendment,
the Board does not have the power to extend the period during which Rights are
redeemable.

     The Rights will expire on July 30, 2000, unless earlier redeemed.

     A copy of the First Amendment to Rights Agreement dated as of January 28,
1999 is attached as an exhibit to the Company's Annual Report of Form 10-K for
the year ended December 31, 1998.


Item 6.  Exhibits and Reports on Form 8-K
         --------------------------------

         a) Exhibits:

            3.2 Second Amended and Restated Bylaws of Health Care Property 
                Investors, Inc.

            27  Financial Data Schedule
 
         b) Reports on Form 8-K:
 
            On January 7, 1999, the Company filed a Report on Form 8-K with the
            SEC regarding the acquisition of 12 long-term care facilities and 13
            medical office buildings in five separate transactions at an
            aggregate purchase price of approximately $125,348,000.

            On March 8, 1999, the Company filed a Report on Form 8-K/A which
            amended the Form 8-K previously filed on January 7, 1999 in order to
            state that neither audited historical financial statements nor pro
            forma financial information concerning the acquired properties was
            required under Rule 3-05 of Regulation S-X.

                                       22

 
                                  SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


Date:  May 13, 1999                 HEALTH CARE PROPERTY INVESTORS, INC.
                                    (REGISTRANT)



                                /s/ James G. Reynolds
                             -------------------------------------------
                             James G. Reynolds
                             Executive Vice President and
                             Chief Financial Officer
                             (Principal Financial Officer)


                               /s/ Devasis Ghose
                             -------------------------------------------
                             Devasis Ghose
                             Senior Vice President-Finance and Treasurer
                             (Principal Accounting Officer)

                                       23