EXHIBIT 16 TO FORM 8-K June 30, 1998 Securities and Exchange Commission 450 Fifth Street, N.W. Washington, DC 20549 Gentlemen: We have read Item 4 of Form 8-K dated June 19, 1998 of Global Med Technologies, Inc. and are in agreement with the statements contained in paragraphs Item 4. (a)(i), (ii) and (iv) on the pages therein. We have no basis to agree or disagree with other statements of the registrant contained therein. /S/ERNST & YOUNG LLP