EXHIBIT 32.1

                    CERTIFICATION OF CHIEF EXECUTIVE OFFICER
            PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

Solely for the purpose of complying with 18 U.S.C. ss.1350, as adopted pursuant
to Section 906 of the Sarbanes-Oxley Act of 2002, I, the undersigned Chief
Executive Officer of Alliance Pharmaceutical Corp. (the "Company"), hereby
certify, based on my knowledge, that the Quarterly Report on Form 10-QSB of the
Company for the three months and nine months ended March 31, 2006 (the "Report")
fully complies with the requirements of Section 13(a) of the Securities and
Exchange Act of 1934 and that information contained in the Report fairly
presents, in all material respects, the financial condition and results of
operations of the Company.

Date:  May 15, 2006


BY: /s/ DUANE J. ROTH
    ---------------------------
        Duane J. Roth
        Chief Executive Officer



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