Exhibit 16.1 May 4, 2009 U.S. Securities and Exchange Commission Office of the Chief Accountant 100 F Street, N.E. Washington, DC 20549 Commissioners: We have read Item 4.01 of Form 8-K, dated May 4, 2009, of Trimedyne, Inc. and agree with the statements concerning our Firm contained therein. Very truly yours, /S/ MCKENNON WILSON & MORGAN LLP McKennon Wilson & Morgan LLP