Exhibit 32.1

                    Certification of Chief Executive Officer
            Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

         Solely for the purpose of complying with 18 U.S.C. ss. 1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, I, the undersigned
Chief Executive Officer of Alliance Pharmaceutical Corp. (the "Company"), hereby
certify, based on my knowledge, that the Quarterly Report on Form 10-Q of the
Company for the nine months ended March 31, 2009 (the "Report") fully complies
with the requirements of Section 13(a) or 15(d) of the Securities and Exchange
Act of 1934 and that information contained in the Report fairly presents, in all
material respects, the financial condition and results of operations of the
Company.

Date:  May 15, 2009





By: /s/ Duane J. Roth
    ----------------------------------
        Duane J. Roth
        Chief Executive Officer