Exhibit 99

                               PURCHASE AGREEMENT

                  THIS AGREEMENT is made as of the 23/rd/ day of January, 2002,
by and between Trimeris, Inc., a corporation organized under the laws of the
State of Delaware (the "Company") with its principal offices at 3518 Westgate
                        -------
Drive, Suite 300, Durham, North Carolina 27707, and the purchaser whose name and
address is set forth on the signature page hereof (the "Purchaser").
                                                        ---------

                  IN CONSIDERATION of the mutual covenants contained in this
Agreement, the Company and the Purchaser agree as follows:

                  SECTION 1. Authorization of Sale of the Shares. The Company
                             -----------------------------------
has authorized the issuance and sale, subject to the terms and conditions of
this Agreement, of up to 1,257,500 shares (the "Shares") of common stock, par
                                                ------
value $.001 per share (the "Common Stock"), of the Company. The Company reserves
                            ------------
the right to increase or decrease the number of shares of Common Stock to be
sold in this private placement prior to the Closing Date.

                  SECTION 2. Agreement to Sell and Purchase the Shares. At the
                             -----------------------------------------
Closing (as defined in Section 3), the Company will sell to the Purchaser and
the Purchaser will buy from the Company, upon the terms and conditions
hereinafter set forth, the number of Shares (at the purchase price) shown below:

                                  Price Per
        Number to Be               Share in                Aggregate
         Purchased                  Dollars                  Price
        ------------              ---------                ---------

                  The Company proposes to enter into this same form of purchase
agreement with certain other investors (the "Other Purchasers") and expects to
                                             ----------------
complete sales of the Shares to them. The Purchaser and the Other Purchasers are
hereinafter sometimes collectively referred to as the "Purchasers," and this
                                                       ----------
Agreement and the agreements executed by the Other Purchasers are hereinafter
sometimes collectively referred to as the "Agreements." The term "Placement
                                           ----------
Agent" shall mean Lehman Brothers Inc. If the Closing Date has not occurred on
or prior to the date that is 120 calendar days after the date hereof, the
Company's obligation to sell and the Purchaser's obligation to purchase the
Shares will expire as of such date.

                  SECTION 3. Delivery of the Shares at the Closing. The
                             -------------------------------------
completion of the purchase and sale of the Shares (the "Closing") shall occur at
                                                        -------
the offices of Wilson Sonsini Goodrich & Rosati, P.C., 12 East 49th St., 30th
Floor, New York, New York 10017 as soon as practicable on the date agreed by the
parties hereto, but in no event later than three business days following the
execution of the Agreements, or on such later date or at such different location
as the parties shall agree in writing, but in any event not prior to the date
that the conditions for Closing set forth below have been satisfied or waived by
the appropriate party (the "Closing Date"). The Closing shall occur
                            ------------




at a time to be agreed upon by the Company and the Placement Agent and of which
the Purchasers will be notified by facsimile transmission or otherwise.

                At the Closing, the Company shall deliver to the Purchaser one
or more stock certificates registered in the name of the Purchaser, or in such
nominee name(s) as designated by the Purchaser in writing, representing the
number of Shares set forth in Section 2 above and bearing an appropriate legend
referring to the fact that the Shares were sold in reliance upon the exemption
from registration under the Securities Act of 1933, as amended (the "Securities
                                                                     ----------
Act") provided by Section 4(2) thereof and Rule 506 thereunder. The name(s) in
- ---
which the stock certificates are to be registered are set forth in the Investor
Suitability Questionnaire attached hereto as part of Appendix I. The Company's
                                                     ----------
obligation to complete the purchase and sale of the Shares and deliver such
stock certificate(s) to the Purchaser at the Closing shall be subject to the
following conditions, any one or more of which may be waived by the Company: (a)
receipt by the Company of same-day funds in the full amount of the purchase
price for the Shares being purchased hereunder; (b) completion of purchases and
sales under the Agreements with each other Purchaser; and (c) the accuracy of
the representations and warranties made by the Purchasers and the fulfillment of
those undertakings of the Purchasers to be fulfilled prior to the Closing. The
Purchaser's obligation to accept delivery of such stock certificate(s) and to
pay for the Shares evidenced thereby shall be subject to the condition that the
representations and warranties made by the Company herein are accurate in all
material respects and that the Company has fulfilled, in all material respects,
all undertakings to be fulfilled prior to Closing. The Purchaser's obligations
hereunder shall be subject to completion of the purchases and sales under all of
the Agreements in an aggregate amount of at least $25,000,000.

                SECTION 4. Representations, Warranties and Covenants of the
                           ------------------------------------------------
Company. The Company as of the date hereof represents and warrants to, and
- -------
covenants with, the Purchaser as follows:

                4.1 Organization and Qualification. The Company is a corporation
                    ------------------------------
duly organized, validly existing and in good standing under the laws of the
State of Delaware and the Company is qualified to do business as a foreign
corporation in each jurisdiction in which qualification is required, except
where failure to be so qualified would not reasonably be expected to have a
Material Adverse Effect (as defined herein). The Company has no Subsidiaries.
True and complete copies of the Company's Certificate of Incorporation and
Bylaws have been filed by the Company with the United States Securities and
Exchange Commission (the "Commission") and have been made available to the
                          ----------
Purchaser. The Company has all requisite power and authority and has all
necessary approvals, licenses, permits and authorizations to own, operate or
lease its properties and to carry on its business as now conducted, except where
the failure to have any such approval, license, permit or authorization would
not reasonably be expected to have a Material Adverse Effect (as defined
herein). For the purposes of this Agreement, the term "Subsidiary" shall mean
                                                       ----------
any (A) firm, corporation, partnership, limited liability company, trust or
other entity (a "Person") of which the Company owns directly or indirectly
                 ------
through a subsidiary, nominee arrangement or otherwise (1) at least a majority
of the outstanding voting capital stock (or other outstanding voting shares of
beneficial interest) or (2) at least a majority of the partnership,

                                       2



membership, joint venture or similar interests, or (B) partnership in which the
Company is a general partner.

                4.2   Authorized Capital Stock. The authorized capital stock of
                      ------------------------
the Company consists of 60,000,000 shares of Common Stock and 10,000,000 shares
of preferred stock, $0.001 par value per share ("Preferred Stock"). As of the
                                                 ---------------
close of business on January 18, 2002, no shares of Preferred Stock were issued
and outstanding, and 17,414,381 shares of the Company's Common Stock were issued
and outstanding; the issued and outstanding shares of the Company's Common Stock
have been duly authorized and validly issued, are fully paid and nonassessable,
have been issued in compliance with all federal and state securities laws and
were not issued in violation of or subject to any preemptive rights or other
rights to subscribe for or purchase securities. Except as disclosed above or in
the filings the Company has made under the Securities Exchange Act of 1934, as
amended (the "Exchange Act") or the Securities Act (collectively, the "SEC
              ------------                                             ---
Filings"), the Company does not have outstanding any options to purchase, or any
- -------
preemptive rights or other rights to subscribe for or to purchase, any
securities or obligations convertible into, or any contracts or commitments to
issue or sell, shares of its capital stock or any such options, rights,
convertible securities or obligations, or any obligation to repurchase, redeem
or otherwise acquire any outstanding security of the Company. Except as
specifically referenced in the SEC Filings, there are no stockholder agreements,
voting agreements or similar agreements or arrangements with respect to the
Common Stock to which the Company is a party, or, to the knowledge of the
Company, between or among any of the Company's stockholders.

                4.3   Issuance, Sale and Delivery of the Shares. The Shares have
                      -----------------------------------------
been duly authorized and, when issued, delivered and paid for in the manner set
forth in this Agreement, will be duly authorized, validly issued, fully paid and
nonassessable. No preemptive rights or other rights to subscribe for or purchase
the Company's capital stock exist with respect to the issuance and sale of the
Shares by the Company pursuant to this Agreement. No stockholder of the Company
has any right (which has not been waived or has not expired by reason of lapse
of time following notification of the Company's intent to file the registration
statement to be filed by it pursuant to Section 7.1 (the "Registration
                                                          ------------
Statement")) to require the Company to register the sale of any shares owned by
- ---------
such stockholder under the Securities Act in the Registration Statement. No
further approval or authority of the stockholders or the Board of Directors of
the Company will be required for the issuance and sale of the Shares by the
Company, or the filing of a registration statement with the Commission, as
contemplated herein.

                4.4   Due Execution, Delivery and Performance of this Agreement.
                      ---------------------------------------------------------
The Company has full legal right, corporate power and authority to enter into
this Agreement and perform the transactions contemplated hereby. This Agreement
has been duly authorized, executed and delivered by the Company. The execution,
delivery and performance of this Agreement by the Company and the consummation
of the transactions contemplated by this Agreement will not violate any
provision of the Certificate of Incorporation or By-laws of the Company in
effect on the date of this Agreement and will not result in the creation of any
lien, charge, security interest or encumbrance upon any assets of the Company
pursuant to the terms or provisions of, or will not conflict with, result in the
breach or violation of, or constitute, either by itself or upon notice or the
passage of time or both, a default under any agreement, mortgage, deed of trust,
lease, franchise,

                                       3



license, indenture, permit or other instrument to which the Company is a party
or by which the Company or any of its respective properties may be bound or
affected and in each case which would have a material adverse effect on the
financial condition, properties, business, prospects or results of operations of
the Company (a "Material Adverse Effect") or, to the Company's knowledge, any
                -----------------------
statute or any authorization, judgment, decree, order, rule or regulation
(collectively, "Laws") of any court or any foreign, federal, state or local
                ----
regulatory body, administrative agency or other governmental body (each, a
"Governmental Authority") applicable to the Company or any of its respective
 ----------------------
properties. No consent, approval, authorization or other order of any court,
regulatory body, administrative agency or other governmental body is required
for the execution and delivery of this Agreement or the consummation of the
transactions contemplated by this Agreement, except for compliance with the Blue
Sky laws and federal securities laws applicable to the offering of the Shares.
Upon its execution and delivery, and assuming the valid execution thereof by the
Purchaser, this Agreement will constitute a valid and binding obligation of the
Company, enforceable in accordance with its terms, except as enforceability may
be limited by applicable bankruptcy, insolvency, reorganization, moratorium or
similar laws affecting creditors' and contracting parties' rights generally and
except as enforceability may be subject to general principles of equity
(regardless of whether such enforceability is considered in a proceeding in
equity or at law) and except as the indemnification agreements of the Company in
Section 7.3 hereof may be held violative of public policy and therefore legally
unenforceable.

                4.5   Accountants. KPMG LLP, who has expressed its opinion with
                      -----------
respect to the consolidated financial statements included in the Company's
Annual Report on Form 10-K, as amended, for the fiscal year ended December 31,
2000 (the "Form 10-K/A"), and incorporated by reference in the Registration
           -----------
Statement and the Prospectus which forms a part thereof, has represented to the
Company that KPMG LLP is an independent accountant as required by the Securities
Act and the rules and regulations promulgated thereunder (the "Rules and
                                                               ---------
Regulations"). The financial statements of the Company and the related notes
- -----------
contained in the SEC Filings present fairly in all material respects the
financial position of the Company as of the dates indicated, and the results of
operations and cash flows for the periods specified therein. Except as specified
in the notes thereto and except, in the case of unaudited interim financial
statements, as may be permitted by the Commission with respect to quarterly
reports on Form 10-Q under the Exchange Act, such financial statements
(including the related notes) have been prepared in accordance with generally
accepted accounting principles ("GAAP") applied on a consistent basis throughout
                                 ----
the periods therein specified, except that the unaudited interim financial
statements do not include footnote disclosure of the type associated with
audited financial statements and were or are subject to normal and recurring
year-end adjustments. Such financial statements are in all material respects in
agreement with the books and records of the Company. The Company keeps proper
accounting records in which all material assets and liabilities, and all
material transactions, of the Company are recorded in conformity with GAAP.

                4.6   No Defaults. Except as disclosed in the SEC Filings, and
                      -----------
except as to defaults, violations and breaches which individually or in the
aggregate, would not have a Material Adverse Effect, the Company is not in
violation or default of any provision of its certificate of incorporation or
bylaws, or in breach of or default with respect to any provision of any
agreement, judgment, decree, order, mortgage, deed of trust, lease, franchise,
license, indenture, permit or other

                                       4



instrument to which it is a party or by which it is or any of its properties
are, bound; and there does not exist any state of fact which, with notice or
lapse of time or both, would constitute an event of default, as defined in such
documents, on the part of the Company, except such defaults which individually,
or in the aggregate, would not have a Material Adverse Effect.

                4.7   Contracts. Except as set forth on Schedule 4.7, all
                      ---------
material agreements to which the Company is a party and which are required to
have been filed by the Company pursuant to the Securities Act, the Exchange Act
and/or the Rules and Regulations have been filed by the Company with the
Commission pursuant to the requirements of the Securities Act and/or the
Exchange Act, as applicable, and the Rules and Regulations. As of the date
hereof, each such agreement is in full force and effect and is binding on the
Company and, to the Company's knowledge, is binding upon such other parties, in
each case in accordance with its terms, and neither the Company nor, to the
Company's knowledge, any other party thereto is in breach of or default under
any such agreement, which breach or default would have a Material Adverse
Effect. The Company has not received any written notice regarding the
termination of any such agreements.

                4.8   No Actions. Except as disclosed in the SEC Filings, there
                      ----------
are no legal or governmental actions, suits or proceedings pending or, to the
Company's knowledge, threatened to which the Company is or may be a party or of
which property owned or leased by the Company is or may be the subject, which
actions, suits or proceedings, individually or in the aggregate, are reasonably
expected to prevent or materially and adversely affect the transactions
contemplated by this Agreement or which, if determined adversely to the Company,
would have a Material Adverse Effect; and, to the Company's knowledge, no labor
disturbance by the employees of the Company exists, or is imminent, which would
reasonably be expected to have a Material Adverse Effect. The Company is not
party to or subject to the provisions of any injunction, judgment, decree or
order of any court, regulatory body administrative agency or other governmental
body, which has, or would reasonably be expected to have, a Material Adverse
Effect.

                4.9   Properties. The Company has good title to all the
                      ----------
properties and assets reflected as owned by it in the financial statements
included in the SEC Filings and that it otherwise purports to own, and such
properties and assets are not subject to any lien, mortgage, pledge, charge,
claim or encumbrance of any kind except (i) those, if any, reflected in the
financial statements included in the SEC Filings, or (ii) those which are not
material in amount and do not adversely affect the use made and intended to be
made of such property by the Company. The Company holds its leased properties
under valid and binding leases, with such exceptions as are not materially
significant in relation to its business. Except as disclosed in the SEC Filings,
the Company owns or leases all such properties as are necessary to its
operations as now conducted.

                4.10  No Material Change. Since September 30, 2001, and except
                      ------------------
as described in the SEC Filings, (i) the Company has not incurred any material
liabilities or obligations, indirect, or contingent, or entered into any
material verbal or written agreement or other transaction that is not in the
ordinary course of business or that could reasonably be expected to result in a
material reduction in the future earnings of the Company; (ii) the Company has
not sustained any material loss or interference with its businesses or
properties from fire, flood, windstorm, accident or other calamity not covered
by insurance; (iii) the Company has not paid or declared any dividends or other

                                       5



distributions with respect to its capital stock and the Company is not in
default in the payment of principal or interest on any outstanding debt
obligations; (iv) there has not been any change in the capital stock of the
Company other than the sale of the Shares hereunder and shares or options issued
pursuant to employee equity incentive plans or purchase plans approved by the
Company's Board of Directors, or any increase in indebtedness material to the
Company (other than in the ordinary course of business); (v) the Company has
conducted its business only in the ordinary course of business in accordance
with past practice; and (vi) there has not been a material adverse change in the
financial condition, properties, business, prospects or results of operations of
the Company.

            4.11 Intellectual Property. Except as disclosed in the SEC Filings
                 ---------------------
and to the Company's knowledge, (i) the Company owns or has obtained valid and
enforceable licenses or options for the inventions, patent applications,
patents, trademarks (both registered and unregistered), trade names, copyrights
and trade secrets necessary for the conduct of the Company's business as
currently conducted (collectively, the "Intellectual Property"); and, (ii) (a)
                                        ---------------------
there are no third parties who have any ownership rights to any Intellectual
Property that is owned by, or has been licensed to, the Company that would
preclude the Company from conducting its business as currently conducted, except
for the ownership rights of the owners of the Intellectual Property licensed or
optioned by the Company; (b) there are currently no sales of any products that
would constitute an infringement by third parties of any Intellectual Property
owned, licensed or optioned by the Company; (c) there is no pending or
threatened action, suit, proceeding or claim by others challenging the rights of
the Company in or to any Intellectual Property owned, licensed or optioned by
the Company, other than claims that would not reasonably be expected to have a
Material Adverse Effect; (d) there is no pending or threatened action, suit,
proceeding or claim by others challenging the validity or scope of any
Intellectual Property owned, licensed or optioned by the Company, other than
non-material actions, suits, proceedings and claims; and (e) there is no pending
or threatened action, suit, proceeding or claim by others that the Company
infringes or otherwise violates any patent, trademark, copyright, trade secret
or other proprietary right of others, other than non-material actions, suits,
proceedings and claims.

            4.12 Compliance. The Company has been advised that, and to the
                 ----------
Company's knowledge, it is conducting business in compliance with all applicable
laws, rules and regulations of the jurisdictions in which it is conducting its
business, including, without limitation, all applicable local, state and federal
environmental laws and regulations; in each case, except where failure to be in
compliance would not have a Material Adverse Effect.

            4.13 Taxes. The Company has filed all necessary federal, state and
                 -----
foreign income and franchise tax returns and has paid or accrued all taxes shown
as due thereon, and the Company has no knowledge of a tax deficiency that has
been or might be asserted or threatened against it that would have a Material
Adverse Effect.

            4.14 Transfer Taxes. On the Closing Date, all stock transfer or
                 --------------
other taxes (other than income taxes) that are required to be paid in connection
with the sale and transfer of the Shares to be sold to the Purchaser hereunder
will be, or will have been, fully paid or provided for by the Company and all
laws imposing such taxes will be or will have been complied with.

                                       6



            4.15 Investment Company. The Company is not an "investment company"
                 ------------------
or an "affiliated person" of, or "promoter" or "principal underwriter" for an
investment company, within the meaning of the Investment Company Act of 1940, as
amended, and will conduct its business in a manner such that it will not become
subject to such Act.

            4.16 Offering Materials. The Company has not distributed and will
                 ------------------
not distribute prior to the Closing Date any offering material in connection
with the offering and sale of the Shares other than the documents described in
Section 4.19 hereof. The Company has not in the past nor will it in the future
take any action to sell, offer for sale or solicit offers to buy any securities
of the Company that would bring the offer, issuance or sale of the Shares, as
contemplated by this Agreement, within the provisions of Section 5 of the
Securities Act, unless such offer, issuance or sale was or shall be exempt from
the registration requirements of the Securities Act and the Rules and
Regulations.

            4.17 Insurance. The Company maintains insurance of the types,
                 ---------
against such losses and in the amounts and with such insurers as are customary
in the Company's industry and otherwise reasonably prudent, including, but not
limited to, insurance covering all real and personal property owned or leased by
the Company against theft, damage, destruction, acts of vandalism and all other
risks customarily insured against by similarly situated companies, all of which
insurance is in full force and effect.

            4.18 Contributions. The Company has not at any time since its
                 -------------
incorporation, directly or indirectly, (i) made any unlawful contribution to any
candidate for public office, or failed to disclose fully any contribution in
violation of law, or (ii) made any payment to any federal or state governmental
officer or official, or other person charged with similar public or quasi-public
duties, other than payments required or permitted by the laws of the United
States or any jurisdiction thereof.

            4.19 Additional Information. The information contained in the
                 ----------------------
following documents, which the Placement Agent has furnished to the Purchaser,
or will furnish prior to the Closing, does not include any untrue statement of a
material fact or omit to state any material fact required to be stated therein
or necessary to make the statements therein, in the light of the circumstances
in which they were made, not misleading, as of their respective filing dates or,
if amended, as so amended:

                 (a)    The confidential private placement memorandum, as dated
            January 22, 2002 (the "PPM");
                                   ---

                 (b)    the Form 10-K/A;

                 (c)    the Company's Quarterly Report on Form 10-Q for the
            three months ended September 30, 2001;

                 (d)    the draft Registration Statement; and

                                       7



                 (e)    all other documents, if any, filed by the Company with
            the Commission since September 30, 2001 pursuant to the reporting
            requirements of the Exchange Act and the Rules and Regulations, as
            amended.

            4.20 Legal Opinion. Prior to the Closing, Wilmer, Cutler &
                 -------------
Pickering, counsel to the Company, will deliver its legal opinion to the
Placement Agent substantially in the form attached hereto as Exhibit A. Such
                                                             ---------
opinion shall also state that each of the Purchasers may rely thereon as though
it were addressed directly to such Purchaser.

            4.21 Intellectual Property Opinion. Prior to the Closing, Pennie &
                 -----------------------------
Edmonds LLP, patent counsel for the Company, will deliver its legal opinion to
the Placement Agent substantially in the form attached hereto as Exhibit B. Such
                                                                 ---------
opinion shall state that each of the Purchasers may rely thereon as though it
were addressed directly to such Purchaser.

            4.22 Commission Reports. The Company has filed with the Commission
                 ------------------
all documents required to be filed with the Commission since December 31, 2000.
Except to the extent that they may have been subsequently amended, superseded or
otherwise modified prior to the date hereof by subsequent reports or filings, as
of their respective filing dates, all such filings complied as to form in all
material respects with the requirements of the Securities Act or the Exchange
Act, as applicable, and the Rules and Regulations. Except to the extent they may
have been subsequently amended, superseded or otherwise modified prior to the
date hereof by subsequent reports or filings, as of their respective filing
dates, each such filing did not contain any untrue statement of material fact or
omit to state a material fact required to be stated therein or necessary to make
the statements therein, in light of the circumstances under which they were
made, not misleading.


            4.23 Rule 144. The Company will file, on a timely basis, the reports
                 --------
required to be filed by it under the Securities Act and the Exchange Act and the
Rules and Regulations (or, if the Company is not required to file such reports
it will, upon the request of any holder of the Shares purchased hereunder, make
publicly available such information as necessary to permit the sales of such
Shares pursuant to Rule 144 under the Securities Act), and it will take such
further action as any such holder may reasonably request to enable such holder
to sell Shares purchased hereunder without registration under the Securities Act
within the limitation of the exemption provided by (A) Rule 144 under the
Securities Act, as amended from time to time; or (B) any similar rule or
regulation hereafter adopted by the Commission. Upon the request of a holder,
the Company will deliver to such holder a written statement as to whether it has
complied with such information and requirements.

            4.24 Form S-3 Eligibility. As of the date hereof, the Company meets
                 --------------------
the requirements for use of Form S-3 for registration of the resale of the
Shares as contemplated herein.

            4.25 Regulatory Matters.
                 ------------------

                 (a)    As to each product subject to the jurisdiction of the
            U.S. Food and Drug Administration ("FDA") under the Federal Food,
            Drug and Cosmetic Act and the Regulations thereunder ("FDCA") (each
            such product, a "Regulated Product") that is manufactured, tested,
            distributed and/or marketed by the Company, such

                                       8



            Regulated Product is being manufactured, tested, distributed and/or
            marketed in substantial compliance with all applicable requirements
            under FDCA and similar state and foreign laws and regulations,
            including but not limited to those relating to investigational use,
            premarket clearance, good manufacturing practices, labeling,
            advertising, record keeping, filing of reports and security, except
            where lack of compliance would not have a Material Adverse Effect.

                 (b)    The Company has not received any written notices or
            correspondence from the FDA or any other Governmental Authority
            requiring the termination, suspension or material modification of
            any tests or evaluations conducted on behalf of the Company.

            4.26 Certificate. At the Closing, the Company will deliver to the
                 -----------
Purchaser a certificate executed by the chief executive officer, the chief
financial or accounting officer or the chief business officer of the Company,
dated the Closing Date, in form and substance reasonably satisfactory to the
Purchaser, to the effect that the representations and warranties of the Company
set forth in this Section 4 are true and correct in all material respects as of
the date of this Agreement and as of the Closing Date, and the Company has
complied in all material respects with all the agreements and satisfied all the
conditions herein on its part to be performed or satisfied on or prior to such
Closing Date.

            SECTION 5. Representations, Warranties and Covenants of the
                       ------------------------------------------------
Purchaser.
- ---------

            5.1  The Purchaser represents and warrants to, and covenants with,
the Company that: (i) the Purchaser is knowledgeable, sophisticated and
experienced in making, and is qualified to make, decisions with respect to
investments in shares representing an investment decision like that involved in
the purchase of the Shares, including investments in securities issued by the
Company, and has requested, received, reviewed and considered all information it
deems necessary and relevant in making an informed decision to purchase the
Shares; (ii) the Purchaser is acquiring the number of Shares set forth in
Section 2 above in the ordinary course of its business and for its own account
for investment purposes only and with no present intention of distributing any
of such Shares, and no arrangement or understanding exists with any other
persons regarding the distribution of such Shares (this representation and
warranty not limiting the Purchaser's right to sell pursuant to the Registration
Statement or, other than with respect to any claims arising out of a breach of
this representation and warranty, the Purchaser's right to indemnification under
Section 7.3); (iii) the Purchaser will not, directly or indirectly, offer, sell,
pledge, transfer or otherwise dispose of (or solicit any offers to buy, purchase
or otherwise acquire or take a pledge of) any of the Shares except in compliance
with the Securities Act and the Rules and Regulations nor will the Purchaser
engage in any short sale that results in a disposition of any of the Shares by
Purchaser in violation of the Securities Act and the Rules and Regulations; (iv)
the Purchaser has completed or caused to be completed the Registration Statement
Questionnaire attached hereto as part of Appendix I, for use in preparation of
                                         ----------
the Registration Statement, and the information in such Registration Statement
Questionnaire is true and correct as of the date hereof and will be true and
correct as of the effective date of the Registration Statement (provided that
Purchaser shall be entitled to update such information prior to the effective
date of the Registration Statement); (v) the Purchaser has, in

                                       9



connection with its decision to purchase the number of Shares set forth in
Section 2 above, relied solely upon the SEC Filings, the PPM, the draft
Registration Statement and the representations and warranties of the Company
contained herein; and (vi) the Purchaser has completed or caused to be completed
the Investor Suitability Questionnaire attached hereto as part of Appendix I,
                                                                  ----------
the information in such Investor Suitability Questionnaire is true and correct
as of the date hereof and will be true and correct as of the Closing, and the
Purchaser is an "accredited investor" within the meaning of Rule 501(a) of
Regulation D promulgated under the Securities Act; and (vii) the Purchaser
agrees to notify the Company immediately of any change in any of the foregoing
information until such time as the Purchaser has sold all of its Shares or the
Company is no longer required to keep the Registration Statement effective.

            5.2  The Purchaser understands that the Shares are being offered and
sold to it in reliance upon specific exemptions from the registration
requirements of the Securities Act, the Rules and Regulations and state
securities laws and that the Company is relying upon the truth and accuracy of,
and the Purchaser's compliance with, the representations, warranties,
agreements, acknowledgments and understandings of the Purchaser set forth herein
in order to determine the availability of such exemptions and the eligibility of
the Purchaser to acquire the Shares.

            5.3  The Purchaser understands that any information provided to the
Purchaser by the Company is strictly confidential and proprietary to the Company
and has been prepared from the Company's publicly available documents and other
information and is being submitted to the Purchaser solely for such Purchaser's
confidential use. The Purchaser agrees to use such information for the sole
purpose of evaluating a possible investment in the Shares and the Purchaser
hereby acknowledges that it is prohibited from reproducing or distributing such
information, this Purchase Agreement, or any other offering materials, in whole
or in part, or divulging or discussing any of their contents except for use
internally and by its legal counsel and except as required by law or legal
process. Further, the Purchaser understands that the existence and nature of all
conversations and presentations, if any, regarding the Company and this offering
must be kept strictly confidential until such time as the Company makes a public
announcement of the sale of Shares, which will occur no later than two business
days following the Closing Date. The Purchaser understands that the federal
securities laws impose restrictions on trading based on information regarding
this offering. In addition, the Purchaser hereby acknowledges that unauthorized
public disclosure of information regarding this offering may cause the Company
to violate Regulation FD.

            5.4  The Purchaser understands that its investment in the Shares
involves a significant degree of risk and that the market price of the Common
Stock has been and continues to be volatile and that no representation is being
made as to the future value of the Common Stock. The Purchaser has the knowledge
and experience in financial and business matters as to be capable of evaluating
the merits and risks of an investment in the Shares and has the ability to bear
the economic risks of an investment in the Shares.

            5.5  The Purchaser understands that no Governmental Authority has
passed upon or made any recommendation or endorsement of the Shares.

            5.6  The Purchaser understands that, until such time as the Shares
may be sold by non-affiliates of the Company pursuant to Rule 144 under the
Securities Act without any restriction

                                       10



as to the number of securities as of a particular date that can then be
immediately sold, the Shares may bear a restrictive legend in substantially the
following form (and a stop-transfer order may be placed against transfer of the
certificates for the Shares):

                "The securities represented by this certificate have not been
registered under the Securities Act of 1933, as amended (the "Act"), or under
the securities laws of any other jurisdiction. The securities may not be sold,
transferred or assigned in the absence of an effective registration statement
for the securities under the Act and applicable state securities laws, or an
opinion of counsel, in form, substance and scope reasonably acceptable to the
Company, that registration is not required under the Act or any applicable state
securities laws or unless sold pursuant to Rule 144 under the Act."

                5.7 The Purchaser's principal executive offices are in the
jurisdiction set forth immediately below the Purchaser's name on the signature
pages hereto.

                5.8 The Purchaser hereby covenants with the Company not to make
any sale of the Shares under the Registration Statement without effectively
causing the prospectus delivery requirement under the Securities Act to be
satisfied, and the Purchaser acknowledges and agrees that such Shares are not
transferable on the books of the Company unless the certificate submitted to the
transfer agent evidencing the Shares is accompanied by a separate Purchaser's
Certificate of Subsequent Sale: (i) in the form of Appendix II hereto, (ii)
                                                   -----------
executed by an officer of, or other authorized person designated by, the
Purchaser, and (iii) to the effect that (A) the Shares have been sold in
accordance with the Registration Statement, the Securities Act and any
applicable state securities or blue sky laws and (B) the requirement of
delivering a current prospectus has been satisfied.

                5.9 The Purchaser further represents and warrants to, and
covenants with, the Company that (i) the Purchaser has full right, power,
authority and capacity to enter into this Agreement and to consummate the
transactions contemplated hereby and has taken all necessary action to authorize
the execution, delivery and performance of this Agreement, and (ii) upon the
execution and delivery of this Agreement, and assuming the valid execution
thereof by the Company, this Agreement shall constitute a valid and binding
obligation of the Purchaser, enforceable in accordance with its terms, except as
enforceability may be limited by applicable bankruptcy, insolvency,
reorganization, moratorium or similar laws affecting creditors' and contracting
parties' rights generally and except as enforceability may be subject to general
principles of equity (regardless of whether such enforceability is considered in
a proceeding in equity or at law) and except as the indemnification agreements
of the Purchaser in Section 7.3 hereof may be held violative of public policy
and therefore legally unenforceable.

                SECTION 6. Survival of Representations, Warranties and
                           -------------------------------------------
Agreements. Notwithstanding any investigation made by any party to this
- ----------
Agreement or by the Placement Agent, all covenants, agreements, representations
and warranties made by the Company and the Purchaser herein and in the
certificates for the Shares delivered pursuant hereto shall survive the
execution of this Agreement, the delivery to the Purchaser of the Shares being
purchased and the payment therefor.

                                       11



                SECTION 7.   Registration of the Shares; Compliance with the
                             -----------------------------------------------
Securities Act.
- --------------

               7.1    Registration Procedures and Expenses.  The Company shall:
                      ------------------------------------

                      (a)    as soon as reasonably practicable, but in no event
                    later than 15 days following the Closing Date, prepare and
               file with the Commission the Registration Statement on Form S-3
               or other available form relating to the sale of the Shares by the
               Purchaser and the Other Purchasers from time to time on the
               Nasdaq National Market or the facilities of any national
               securities exchange on which the Common Stock is then traded or
               in privately-negotiated transactions;

                      (b)    use commercially reasonable efforts, subject to
               receipt of necessary information from the Purchasers, to cause
               the Registration Statement to become effective promptly following
               clearance by the Commission and, in any event, use its
               commercially reasonable efforts, subject to receipt of necessary
               information from the Purchasers, to cause the Commission to
               declare the Registration Statement effective within 75 days after
               the Closing Date;


                      (c)    use its commercially reasonable efforts to promptly
               prepare and file with the Commission such amendments and
               supplements to the Registration Statement and the prospectus used
               in connection therewith as may be necessary to comply with the
               provisions of the Securities Act with respect to the disposition
               of the Shares (subject to the Company receiving notification and
               all necessary information from the selling stockholders described
               therein and their respective transferees, assignees and donees)
               and keep the Registration Statement effective and free from any
               material misstatement or omission until the date on which the
               Shares may be resold by non-affiliates of the Company without
               registration by reason of Rule 144(k) under the Securities Act or
               any other rule of similar effect;

                      (d)    furnish to the Purchaser with respect to the Shares
               registered under the Registration Statement (and to each
               underwriter, if any, of such Shares) such number of copies of
               prospectuses and all amendments thereof or supplements thereto
               and such other documents as the Purchaser may reasonably request,
               in order to facilitate the public sale or other disposition of
               all or any of the Shares by the Purchaser; provided, however,
                                                          --------  -------
               that the obligation of the Company to deliver copies of
               prospectuses to the Purchaser shall be subject to the receipt by
               the Company of reasonable assurances from the Purchaser that the
               Purchaser will comply with the applicable provisions of the
               Securities Act and of such other securities or blue sky laws as
               may be applicable in connection with any use of such
               prospectuses;

                      (e)    file documents required of the Company for normal
               blue sky clearance in states specified in writing by the
               Purchaser and keep such qualification or registration in effect
               for so long as the Registration Statement is in effect; provided,
                                                                       --------
               however, that the Company shall not be required to qualify to do
               -------
               business or consent to service of process in any jurisdiction in
               which it is not now so qualified or has not so consented; and

                                       12



                      (f)    notify the holder of any Shares purchased hereunder
               as promptly as practicable (1) when a prospectus or any
               prospectus supplement or post-effective amendment with respect to
               the Registration Statement is proposed to be filed; (2) when the
               Registration Statement has become effective; (3) of any request
               by the Commission or any other Governmental Authority for
               amendments or supplements to the Registration Statement or
               related prospectus or for additional information; (4) of the
               issuance by the Commission of any stop order suspending the
               effectiveness of the Registration Statement or the initiation of
               any proceeding for that purpose; or (5) of the receipt by the
               Company of any notification with respect to the suspension of the
               qualification or exemption from qualification of any Shares for
               sale in any jurisdiction, or the initiation or threatening of any
               proceeding for such purpose;

                      (g)    provide a transfer agent and registrar for all
               Shares covered by the Registration Statement not later than the
               effective date of the Registration Statement;

                      (h)    timely notify the Nasdaq National Market of the
               issuance of the Shares;

                      (i)    bear all expenses in connection with the procedures
               in paragraphs (a) through (h) of this Section 7.1 and the
               registration of the Shares pursuant to the Registration
               Statement, other than fees and expenses, if any, of counsel or
               other advisers to the Purchaser or the Other Purchasers or
               underwriting discounts, brokerage fees and commissions incurred
               by the Purchaser or the Other Purchasers, if any.

               The Company understands that the Purchaser disclaims being an
underwriter, but the Purchaser being deemed an underwriter shall not relieve the
Company of any obligations it has hereunder. A questionnaire related to the
Registration Statement to be completed by the Purchaser is attached hereto as
Appendix I.
- ----------

               7.2    Transfer of Shares After Registration. The Purchaser
                      -------------------------------------
agrees that it will not effect any disposition of the Shares or its right to
purchase the Shares that would constitute a sale within the meaning of the
Securities Act, except as contemplated in the Registration Statement referred to
in Section 7.1 in the section titled "Plan of Distribution," or in compliance
with Rule 144 or another exemption from registration and that it will promptly
notify the Company of any changes in the information set forth in the
Registration Statement regarding the Purchaser or its plan of distribution.

               7.3    Indemnification.  For the purpose of this Section 7.3:
                      ---------------

                      (i)    the term "Purchaser/Affiliate" shall mean any
                             affiliates of the Purchaser and any person who
                             controls the Purchaser or any affiliate of the
                             Purchaser within the meaning of Section 15 of the
                             Securities Act or Section 20 of the Exchange Act;
                             and

                                       13



                      (ii)   the term "Registration Statement" shall include any
                             final prospectus, exhibit, supplement or amendment
                             included in or relating to, and any document
                             incorporated by reference in, the Registration
                             Statement referred to in Section 7.1.

                      (a)    The Company agrees to indemnify and hold harmless
     the Purchaser and each Purchaser/Affiliate, against any losses, claims,
     damages, liabilities or expenses, joint or several, to which the Purchaser
     or such Purchaser/Affiliates may become subject, under the Securities Act,
     the Exchange Act, or any other federal or state statutory Law or
     regulation, or at common law or otherwise (including in settlement of any
     litigation, if such settlement is effected with the written consent of the
     Company, which consent shall not be unreasonably withheld), insofar as such
     losses, claims, damages, liabilities or expenses (or actions in respect
     thereof as contemplated below) arise out of or are based upon: (i) any
     untrue statement or alleged untrue statement of any material fact contained
     in the Registration Statement, including the prospectus, financial
     statements and schedules, and all other documents filed as a part thereof,
     as amended at the time of effectiveness of the Registration Statement,
     including any information deemed to be a part thereof as of the time of
     effectiveness pursuant to paragraph (b) of Rule 430A, or pursuant to Rule
     434, of the Rules and Regulations, or the prospectus, in the form first
     filed with the Commission pursuant to Rule 424(b) of the Regulations, or
     filed as part of the Registration Statement at the time of effectiveness if
     no Rule 424(b) filing is required (the "Prospectus"), or any amendment or
                                             ----------
     supplement thereto; (ii) the omission or alleged omission to state in any
     of them a material fact required to be stated therein or necessary to make
     the statements in the Registration Statement or any amendment or supplement
     thereto not misleading or in the Prospectus or any amendment or supplement
     thereto not misleading in the light of the circumstances under which they
     were made; (iii) in whole or in part, any inaccuracy in the representations
     and warranties of the Company contained in this Agreement; or (iv) any
     failure of the Company to perform its obligations hereunder or under Law,
     and will reimburse the Purchaser and each such Purchaser/Affiliate for any
     legal and other expenses as such expenses are reasonably incurred by the
     Purchaser or such Purchaser/Affiliate in connection with investigating,
     defending, settling, compromising or paying any such loss, claim, damage,
     liability, expense or action; provided, however, that the Company will not
                                   --------  -------
     be liable in any such case to the extent that any such loss, claim, damage,
     liability or expense arises out of or is based upon: (i) an untrue
     statement or alleged untrue statement or omission or alleged omission made
     in the Registration Statement, the Prospectus or any amendment or
     supplement thereto in reliance upon and in conformity with written
     information furnished to the Company by or on behalf of the Purchaser
     expressly for use therein; (ii) the failure of the Purchaser to comply with
     the covenants and agreements contained in Sections 5.8 or 7.2 hereof
     respecting the sale of the Shares; (iii) the inaccuracy of any
     representations or warranties made by the Purchaser herein; or (iv) any
     statement or omission in any Prospectus that is corrected in any subsequent
     Prospectus that was delivered to the Purchaser prior to the pertinent sale
     or sales by the Purchaser.

                                       14



                (b)  The Purchaser will indemnify and hold harmless the Company,
          each of its directors, each of its officers who signed the
          Registration Statement and each person, if any, who controls the
          Company within the meaning of Section 15 of the Securities Act or
          Section 20 of the Exchange Act, against any losses, claims, damages,
          liabilities or expenses to which the Company, each of its directors,
          each of its officers who signed the Registration Statement or
          controlling person may become subject, under the Securities Act, the
          Exchange Act, or any other federal or state statutory law or
          regulation, or at common law or otherwise (including in settlement of
          any litigation, if such settlement is effected with the written
          consent of the Purchaser) insofar as such losses, claims, damages,
          liabilities or expenses (or actions in respect thereof as contemplated
          below) arise out of or are based upon (i) any failure to comply with
          the covenants and agreements contained in Sections 5.8 or 7.2 hereof
          respecting the sale of the Shares or (ii) the inaccuracy of any
          representation or warranty made by the Purchaser herein or (iii) any
          untrue or alleged untrue statement of any material fact contained in
          the Registration Statement, the Prospectus, or any amendment or
          supplement thereto, or arise out of or are based upon the omission or
          alleged omission to state therein a material fact required to be
          stated therein or necessary to make the statements in the Registration
          Statement or any amendment or supplement thereto not misleading or in
          the Prospectus or any amendment or supplement thereto not misleading
          in the light of the circumstances under which they were made, in each
          case to the extent, but only to the extent, that such untrue statement
          or alleged untrue statement or omission or alleged omission was made
          in the Registration Statement, the Prospectus, or any amendment or
          supplement thereto, in reliance upon and in conformity with written
          information furnished to the Company by the Purchaser expressly for
          use therein, and will reimburse the Company, each of its directors,
          each of its officers who signed the Registration Statement or
          controlling person for any legal and other expense reasonably incurred
          by the Company, each of its directors, each of its officers who signed
          the Registration Statement or controlling person in connection with
          investigating, defending, settling, compromising or paying any such
          loss, claim, damage, liability, expense or action.

                (c)  Promptly after receipt by an indemnified party under this
          Section 7.3 of notice of the threat or commencement of any action,
          such indemnified party will, if a claim in respect thereof is to be
          made against an indemnifying party under this Section 7.3 promptly
          notify the indemnifying party in writing thereof; but the omission to
          notify the indemnifying party promptly will not relieve it from any
          liability which it may have to any indemnified party for contribution
          or otherwise than under the indemnity agreement contained in this
          Section 7.3 or to the extent it is not prejudiced as a result of such
          failure. In case any such action is brought against any indemnified
          party and such indemnified party seeks or intends to seek indemnity
          from an indemnifying party, the indemnifying party will be entitled to
          participate in, and, to the extent that it may wish, jointly with all
          other indemnifying parties similarly notified, to assume the defense
          thereof with counsel reasonably satisfactory to such indemnified
          party; provided, however, if the defendants in any such action include
                 --------  -------
          both the indemnified party and the indemnifying party, and the
          indemnified

                                       15



          party, based upon the advice of such indemnified party's counsel,
          shall have reasonably concluded that there may be a conflict of
          interest between the positions of the indemnifying party and the
          indemnified party in conducting the defense of any such action or that
          there may be legal defenses available to it and/or other indemnified
          parties which are different from or additional to those available to
          the indemnifying party, the indemnified party or parties shall have
          the right to select separate counsel to assume such legal defenses and
          to otherwise participate in the defense of such action on behalf of
          such indemnified party or parties. Upon receipt of notice from the
          indemnifying party to such indemnified party of its election so to
          assume the defense of such action and approval by the indemnified
          party of counsel, the indemnifying party will not be liable to such
          indemnified party under this Section 7.3 for any legal or other
          expenses subsequently incurred by such indemnified party in connection
          with the defense thereof unless (i) the indemnified party shall have
          employed such counsel in connection with the assumption of legal
          defenses in accordance with the proviso to the preceding sentence (it
          being understood, however, that the indemnifying party shall not be
          liable for the expenses of more than one separate counsel, approved by
          such indemnifying party in the case of paragraph (a), representing the
          indemnified parties who are parties to such action, plus local
          counsel, if appropriate) or (ii) the indemnifying party shall not have
          employed counsel reasonably satisfactory to the indemnified party to
          represent the indemnified party within a reasonable time after notice
          of commencement of action, in each of which cases the reasonable fees
          and expenses of counsel shall be at the expense of the indemnifying
          party.

               (d) If the indemnification provided for in this Section 7.3 is
          required by its terms but is for any reason held to be unavailable to
          or otherwise insufficient to hold harmless an indemnified party under
          paragraphs (a), (b) or (c) of this Section 7.3 in respect to any
          losses, claims, damages, liabilities or expenses referred to herein,
          then each applicable indemnifying party shall contribute to the amount
          paid or payable by such indemnified party as a result of any losses,
          claims, damages, liabilities or expenses referred to herein (i) in
          such proportion as is appropriate to reflect the relative benefits
          received by the Company and the Purchaser from the placement of the
          Common Stock contemplated by this Agreement or (ii) if the allocation
          provided by clause (i) above is not permitted by applicable law, in
          such proportion as is appropriate to reflect not only the relative
          benefits referred to in clause (i) above but the relative fault of the
          Company and the Purchaser in connection with the statements or
          omissions or inaccuracies in the representations and warranties in
          this Agreement that resulted in such losses, claims, damages,
          liabilities or expenses, as well as any other relevant equitable
          considerations. The relative benefits received by the Company on the
          one hand and the Purchaser on the other shall be deemed to be in the
          same proportion as the amount paid by the Purchaser to the Company
          pursuant to this Agreement for the Shares purchased by the Purchaser
          that were sold pursuant to the Registration Statement bears to the
          difference (the "Difference") between the amount the Purchaser paid
          for the Shares that were sold pursuant to the Registration Statement
          and the amount received by the Purchaser from such sale. The relative

                                       16



          fault of the Company on the one hand and the Purchaser on the other
          shall be determined by reference to, among other things, whether the
          untrue or alleged statement of a material fact or the omission or
          alleged omission to state a material fact or the inaccurate or the
          alleged inaccurate representation and/or warranty relates to
          information supplied by the Company or by the Purchaser and the
          parties' relative intent, knowledge, access to information and
          opportunity to correct or prevent such statement or omission. The
          amount paid or payable by a party as a result of the losses, claims,
          damages, liabilities and expenses referred to above shall be deemed to
          include, subject to the limitations set forth in paragraph (c) of this
          Section 7.3, any legal or other fees or expenses reasonably incurred
          by such party in connection with investigating or defending any action
          or claim. The provisions set forth in paragraph (c) of this Section
          7.3 with respect to the notice of the threat or commencement of any
          threat or action shall apply if a claim for contribution is to be made
          under this paragraph (d); provided, however, that no additional notice
                                    --------  -------
          shall be required with respect to any threat or action for which
          notice has been given under paragraph (c) for purposes of
          indemnification. The Company and the Purchaser agree that it would not
          be just and equitable if contribution pursuant to this Section 7.3
          were determined solely by pro rata allocation (even if the Purchaser
          were treated as one entity for such purpose) or by any other method of
          allocation which does not take account of the equitable considerations
          referred to in this paragraph. Notwithstanding the provisions of this
          Section 7.3, the Purchaser shall not be required to contribute any
          amount in excess of the amount by which the Difference exceeds the
          amount of any damages that the Purchaser has otherwise been required
          to pay by reason of such untrue or alleged untrue statement or
          omission or alleged omission. No person guilty of fraudulent
          misrepresentation (within the meaning of Section 11(f) of the
          Securities Act) shall be entitled to contribution from any person who
          was not guilty of such fraudulent misrepresentation.

          7.4  Termination of Conditions and Obligations. The conditions
               -----------------------------------------
precedent imposed by Section 5 or Section 7.2 upon the transferability of the
Shares shall cease and terminate as to any particular number of the Shares upon
the passage of two years from the Closing or at such time as an opinion of
counsel reasonably satisfactory in form and substance to the Company shall have
been rendered to the effect that such conditions are not necessary in order to
comply with the Securities Act.

          7.5  Information Available. So long as the Registration Statement
               ---------------------
covering the resale of Shares owned by the Purchaser is effective, the Company
will furnish to the Purchaser:

               (a)  as soon as practicable after available (but in the case of
          the Company's Annual Report to Stockholders, within 150 days after the
          end of each fiscal year of the Company), one copy of (i) its Annual
          Report to Stockholders (which Annual Report shall contain financial
          statements audited in accordance with GAAP by a national firm of
          certified public accountants), (ii) if not included in substance in
          the Annual Report to Stockholders, upon the request of the Purchaser,
          its Annual Report on Form 10-K, (iii) upon the request of the
          Purchaser, its Quarterly Reports on Form

                                       17



          10-Q, (iv) upon the request of the Purchaser, its Current Reports on
          Form 8-K, and (v) a full copy of the particular Registration Statement
          covering the Shares (the foregoing, in each case, excluding exhibits);

                (b)  upon the request of the Purchaser, all exhibits excluded by
          the parenthetical to subparagraph (a)(v) of this Section 7.5; and

                (c)  upon the request of the Purchaser, a reasonable number of
          copies of the prospectuses to supply to any other party requiring such
          prospectuses;

and the Company, upon the reasonable request of the Purchaser, will meet with
the Purchaser and/or a representative thereof at the Company's headquarters to
discuss information relevant for disclosure in the Registration Statement
covering the Shares.

          7.6   Blackout Periods. Notwithstanding anything to the contrary in
                ----------------
Section 5.8 or this Section 7, at any time after the Registration Statement has
been declared effective, the Company may delay the filing of amendments and
supplements to the Registration Statement and the disclosure of material
non-public information concerning the Company, the filing or disclosure of which
at the time is not, in the good faith opinion of the Company and its counsel, in
the best interest of the Company (a "Grace Period"); provided, that the Company
                                     ------------    --------
shall promptly (i) notify the Purchasers in writing of the existence (but not
the nature) of material non-public information giving rise to a Grace Period and
the date on which the Grace Period will begin, and (ii) notify the Purchasers in
writing in advance of, or on the same date on which, the Grace Period ends; and,
provided further, that during any consecutive 365 day period, there shall be not
- ----------------
more than two Grace Periods, such Grace Periods in total not to exceed 45 days.
For purposes of determining the length of a Grace Period above, the Grace Period
shall begin on and include the date the holders receive the notice referred to
in clause (i) and shall end on and include the date specified as the Grace
Period ending date in the notice referred to in clause (ii). If at any time
after the Registration Statement has been declared effective, the Company
suspends the use of the Registration Statement by the Purchaser, other than
during a permitted Grace Period as described above, the Company shall make
payments to the Purchaser as provided in the next sentence as liquidated damages
intended by the parties to compensate the Purchaser in part for the incremental
costs and investment risks associated with holding the Shares as restricted
securities and not as a penalty. The amount of payments shall be equal to
0.0833% of the Aggregate Price (as set forth in Section 2) for each day on which
the Company has suspended the use of the Registration Statement by the
Purchaser, other than during a permitted Grace Period. Nothing herein shall
limit the rights of any Investor to pursue actual damages for the Investor's
inability to sell any of the Registrable Securities into the public market for
any reason described in this section.

          SECTION 8. Broker's Fee. The Purchaser acknowledges that the Company
                     ------------
intends to pay to the Placement Agent a fee in respect of the sale of the Shares
to the Purchaser. Each of the parties hereto hereby represents that, on the
basis of any actions and agreements by it, there are no other brokers or finders
entitled to compensation in connection with the sale of the Shares to the
Purchaser.

                                       18



          SECTION 9.  Notices. All notices, requests, consents and other
                      -------
communications hereunder shall be in writing, shall be mailed by first-class
registered or certified airmail, confirmed facsimile or nationally recognized
overnight express courier postage prepaid, and shall be deemed given when so
mailed and shall be delivered as addressed as follows:

               (a)    if to the Company, to:

                            Trimeris, Inc.
                            3518 Westgate Drive, Suite 300
                            Durham, NC 27707
                            Attention: Robert R. Bonczek
                            Facsimile: (919) 419-1816

                      with a copy to:

                            Wilmer, Cutler & Pickering
                            2445 M Street
                            Washington, D.C. 20037-1420
                            Attention: John B. Watkins, Esq.
                            Facsimile: (410) 986-2828

                      or to such other person at such other place as the Company
                      shall designate to the Purchaser in writing; and

               (b)    if to the Purchaser, at its address as set forth at the
          end of this Agreement, or at such other address or addresses as may
          have been furnished to the Company in writing.

          SECTION 10. Changes. This Agreement may not be modified or amended
                      -------
except pursuant to an instrument in writing signed by the Company and the
Purchaser.

          SECTION 11. Headings. The headings of the various sections of this
                      --------
Agreement have been inserted for convenience of reference only and shall not be
deemed to be part of this Agreement.

          SECTION 12. Severability. In case any provision contained in this
                      ------------
Agreement should be invalid, illegal or unenforceable in any respect, the
validity, legality and enforceability of the remaining provisions contained
herein shall not in any way be affected or impaired thereby.

          SECTION 13. Governing Law. This Agreement shall be governed by and
                      -------------
construed in accordance with the laws of the State of New York, without regard
to conflict of laws.

          SECTION 14. Counterparts. This Agreement may be executed in two or
                      ------------
more counterparts, each of which shall constitute an original, but all of which,
when taken together, shall constitute but one instrument, and shall become
effective when one or more counterparts have been

                                       19



signed by each party hereto and delivered to the other parties. Facsimile
signatures shall be deemed original signatures.

          SECTION 15. Entire Agreement. This Agreement and the instruments
                      ----------------
referenced herein contain the entire understanding of the parties with respect
to the matters covered herein and therein and, except as specifically set forth
herein or therein, neither the Company nor the Purchaser makes any
representation, warranty, covenant or undertaking with respect to such matters.

          SECTION 16. Third Party Beneficiaries. This Agreement is intended for
                      -------------------------
the benefit of the parties hereto and their respective permitted successors and
assigns, and, except as may be required under Section 7.3, is not for the
benefit of, nor may any provision hereof be enforced by, any other person.

          SECTION 17. Assignment. This Agreement and the rights of the Purchaser
                      ----------
hereunder may not be assigned by Purchaser without the prior written consent of
the Company (except (x) by operation of law; (y) by the Purchaser to its wholly
owned subsidiary; or (z) by an investment advisor to a fund for which it is the
advisor or by or among funds that are under common control or that share the
same investment advisor or affiliates of the same investment advisor, provided
that such assignee agrees to be bound by the terms of this Agreement) and shall
be binding upon and shall inure to the benefit of the parties hereto and their
respective permitted successors, heirs and legal representatives.

          SECTION 18. Limitation of Liability. A copy of the Agreement and
                      -----------------------
Declaration of Trust of each of Putnam OTC and Emerging Growth Fund; Putnam
Variable Trust-Putnam VT OTC and Emerging Growth Fund; Putnam Funds Trust-
Putnam Equity Fund 2000; and TH Lee, Putnam Investment Trust-TH Lee, Putnam
Emerging Opportunities Portfolio, each of which is a series investment company
that is a Massachusetts business trust, is on file with the Secretary of State
of The Commonwealth of Massachusetts and notice is hereby given that this
Agreement is executed on behalf of the Trustees of each such entity as Trustees
and not individually and that the obligations of this Agreement are not binding
upon any of the Trustees, officers or shareholders of such entities individually
but are binding only upon the assets and property of such entities.

                                       20



     IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed by their duly authorized representatives as of the day and year first
above written.

                                             TRIMERIS, INC.


                                             By:________________________________
                                                Name:
                                                Title:


Print or Type:
                                             Name of Purchaser
                                              (Individual or Institution):

                                             ___________________________________

                                             Name of Individual representing
                                              Purchaser (if an Institution):

                                             ___________________________________

                                             Title of Individual representing
                                              Purchaser (if an Institution):

                                             ___________________________________


Signature by:
                                             Individual Purchaser or Individual
                                              representing Purchaser:

                                             ___________________________________

                                             Address:   ________________________

                                             Telephone: ________________________

                                             Facsimile: ________________________

                                       21



                                  Schedule 4.7
                                  ------------

1.   In September 2001, the Company entered into a Lease Assignment and
Modification Agreement with Blue Cross and Blue Shield of North Carolina
("BCBS") and Hamad Jassim Althani ("Landlord") by which, effective December 31,
2001, BCBS assigned all rights, title and interest in the existing Lease with
the Landlord for the office space at 3518 Westgate Drive, Suite 300, Durham,
North Carolina (which the Company occupies) to the Company and extended the term
of the existing Lease from December 31, 2001 until December 31, 2002.

2.   On November 30, 2001, the Company entered into a Third Amendment to Lease
Agreement with Hamad Jassim Althani ("Landlord") to extend the term of Lease for
its office space at 3518 Westgate Drive, Suite 300, Durham, North Carolina from
December 31, 2002 until December 31, 2003.

3.   On December 14, 2001, the Company entered into an Agreement of Sublease for
18,903 square feet of additional laboratory space in a building adjacent to its
present facilities at 4727 University Drive, Durham, North Carolina with
Triangle Pharmaceuticals, Inc. The Lease expires on September 30, 2003 and is
subject to standard terms and conditions found in lease arrangements.

The Company will file these three agreements as Exhibits to its Form 10-K for
the year ending December 31, 2001.

                                       22



                     SUMMARY INSTRUCTION SHEET FOR PURCHASER
                     ---------------------------------------

                   (to be read in conjunction with the entire
                        Purchase Agreement which follows)


A.     Complete the following items on BOTH Purchase Agreements:

       1.   Page 21 - Signature:

            (i)    Name of Purchaser (Individual or Institution)

            (ii)   Name of Individual representing Purchaser (if an Institution)

            (iii)  Title of Individual representing Purchaser (if an
                   Institution)

            (iv)   Signature of Individual Purchaser or Individual representing
                   Purchaser

       2.   Appendix I - Investor Suitability Questionnaire and Registration
            ----------
            Statement Questionnaire:

            Provide the information requested by the Investor Suitability
            Questionnaire and Registration Statement Questionnaire.

       3.   Return BOTH properly completed and signed Purchase Agreements
            including the properly completed Appendix I (initially by facsimile
                                                         ----------------------
            with hard copy by overnight delivery) to:
            ------------------------------------

                   Lehman Brothers Inc.
                   The Sheraton Manhattan
                   790 Seventh Avenue
                   New York, New York 10019
                   Attention: Peter Bennett
                              Caroline Brady
                   Facsimile: 646-758-5254

B.     Instructions regarding the transfer of funds for the purchase of Shares
       will be sent by facsimile to the Purchaser by the Placement Agent at a
       later date.

C.     Upon the resale of the Shares by the Purchasers after the Registration
       Statement covering the Shares is effective, as described in the Purchase
       Agreement, the Purchaser:

            (i)    must deliver a current prospectus of the Company to the buyer
                   (prospectuses must be obtained from the Company at the
                   Purchaser's request); and

            (ii)   must send a letter in the form of Appendix II to the Company
                                                     -----------
                   so that the Shares may be properly transferred.

                                       23



                                                                      Appendix I

                                 TRIMERIS, INC.
                       INVESTOR SUITABILITY QUESTIONNAIRE
                       ----------------------------------

     Pursuant to Section 3 of the Agreement, please provide us with the
following information:

     Trimeris, Inc., a Delaware corporation (the "Company"), will use the
responses to this questionnaire to qualify prospective investors for purposes of
federal and state securities laws. This is not an offer to sell or the
solicitation of an offer to buy securities. Such an offer can only be made by
appropriate offering documentation. Any such offer may be conditioned upon your
qualification as an investor under federal and state securities laws.

     Please complete, sign, date and return one copy of this questionnaire in
            --------  ----  ----     ------
accordance with the instructions on the Summary Instruction Sheet for Purchaser
on the previous page.

     Individual investors should complete only pages 2-5 and sign on page 9.
     --------------------
Other investors (partnerships, trusts, corporations, etc.) should complete only
- ---------------
pages 6-9. If the answer to any question is "none" or "not applicable", please
so indicate.

     Your answers will be kept confidential at all times. However, by signing
this questionnaire, you agree that the Company may present this questionnaire to
such parties as it deems appropriate to establish the availability of exemptions
from registration under state and federal securities laws.

Investor:         ______________________________________________________________
                  Exact name as it should appear on the stock certificate. If
                  the name is a "nominee name", please so state and provide, in
                  addition, the name of the legal owner.

Address:          ______________________________________________________________

                  ______________________________________________________________

                  ______________________________________________________________
                  Address for shareholder records. All notices and mailings will
                  be made to this address. Indicate, if appropriate, the person
                  at that address to whose attention the mailing should be
                  directed.

                                      I-1



                             I. INDIVIDUAL INVESTORS

         (INVESTORS OTHER THAN INDIVIDUALS SHOULD TURN TO PAGE 6)

1.       PERSONAL
         --------

         Name __________________________________________________________________

         Residence Address _____________________________________________________

         Home Telephone ________________________________________________________

         Date of Birth _________________________________________________________

         Social Security Number ________________________________________________

2.       BUSINESS
         --------

         Occupation ____________________________________________________________

         Number of Years _______________________________________________________

         Present Employer ______________________________________________________

         Position/Title ________________________________________________________

         Business Address ______________________________________________________

         Business Telephone ____________________________________________________

3.       RESIDENCE INFORMATION
         ---------------------

          (a)    Set forth in the space provided below the state(s) in which you
                 have maintained your principal residence during the past three
                 years and the dates during which you resided in each state.

                 _______________________________________________________________

                 _______________________________________________________________

          (b)    Are you registered to vote in, or do you have a driver's
                 license issued by, or do you maintain a residence in any other
                 state? If yes, in which state(s)?

                 _______________________________________________________________

                                      I-2



4.       INCOME
         ------

         (a)      Was your individual income from all sources during each of the
                  last two years in excess of $200,000 or was the joint income
                  of you and your spouse (if married) from all sources during
                  each of such years in excess of $300,000?

                           Yes _____         No _____

                  If no, please specify amount and indicate if income was
individual or joint:

Last Year: $___________
                                 Year Before Last: $___________

         (b)      Do you reasonably expect either your own income from all
                                           ------
                  sources during the current year to exceed $200,000 or the
                                                                     --
                  joint income of you and your spouse (if married) from all
                  sources during the current year to exceed $300,000?

                           Yes _____         No _____  If not, please specify
                                                          amount _______________

                  What percentage of your income as shown above is anticipated
                  to be derived from sources other than salary?_____________

5.       NET WORTH
         ---------

         Will your net worth as of the date you purchase the securities offered,
         together with the net worth of your spouse, be in excess of $1,000,000?

                           Yes _____         No _____  If not, please specify
                                                          amount _______________

         Will your investment in these securities exceed 10% of your net worth?

                           Yes _____   No


6.       AFFILIATION
         -----------

         If you have any pre-existing personal or business relationship with the
         Company or any of its officers, directors or controlling persons,
         please describe the nature and duration of such relationship.

         _____________________________________________________________

         _____________________________________________________________

         _____________________________________________________________

                                      I-3



7.   BUSINESS AND FINANCIAL EXPERIENCE
     ---------------------------------

     (a)      Please describe in reasonable detail the nature and extent of
              your business, financial and investment experience which you
              believe gives you the capacity to evaluate the merits and
              risks of the proposed investment and the capacity to protect
              your interests.

              --------------------------------------------------------

              --------------------------------------------------------

              --------------------------------------------------------

              --------------------------------------------------------

              --------------------------------------------------------

     (b)      Are you purchasing the securities offered for your own account
              and for investment purposes only?

                       Yes                       No
                           -----                    -----

              If no, please state for whom you are investing and/or the
              reason for investing.

              --------------------------------------------------------

              --------------------------------------------------------

8.   FINANCIAL ADVISORS

     In evaluating this investment, will you be relying on the services of
     any of the following advisors? (If so, please identify, providing
     address and telephone number.)

     Accountant:                --------------------------------

                                --------------------------------

                                --------------------------------


     Attorney:                  --------------------------------

                                --------------------------------

                                --------------------------------

                                      I-4



         Other:                     --------------------------------

                                    --------------------------------

                                    --------------------------------


         PLEASE TURN TO PAGE 9 AND SIGN AND DATE THIS QUESTIONNAIRE

                                      I-5



                          II. NON-INDIVIDUAL INVESTORS
                              ------------------------

  (Please answer Part II only if the purchase is proposed to be undertaken by a
                   corporation, partnership or other entity.)

IF INVESTMENT WILL BE MADE BY MORE THAN ONE AFFILIATED ENTITY, PLEASE COMPLETE A
COPY OF THIS QUESTIONNAIRE FOR EACH ENTITY.
                               ----

1.       IDENTIFICATION
         --------------

         Name ________________________________________________________
                   (Exact name as it will appear on stock certificate)

         Address of Principal
            Place of Business ________________________________________

         State (or Country) of Formation
           or Incorporation __________________________________________

         Contact Person ______________________________________________

         Telephone Number (        )
                          ------------------------------

         Type of Entity (corporation, partnership, trust, etc.) ________________

         Taxpayer or Employer Identification Number  ___________________________

         Was entity formed for the purpose of this investment?

                  Yes                       No
                      -----                    -----

         If the answer is yes, all shareholders, partners or other equity owners
         must answer Part I of this Questionnaire. If the above answer is no,
         please continue completing this form.

2.       PROPOSED INVESTMENT
         -------------------

         Please indicate the amount of your proposed investment: $____________

         Please state the investing entity's approximate net worth at the time
         the securities will be purchased: $_______________

3.       DESCRIPTION OF INVESTOR
         -----------------------

         Please check the appropriate box to indicate which of the following
         describes the investing entity:

         [_]     a corporation or partnership with total assets in excess of
                $5,000,000, not organized for the purpose of this particular
                investment;

                                      I-6





     [_]  private business development company as defined in Section
          202(a)(22) of the Investment Advisers Act of 1940 (a U.S. venture
          capital fund which invests primarily through private placements in
          non-publicly traded securities and makes available (either directly or
          through co-investors) to the portfolio companies significant guidance
          concerning management, operations or business objectives);

     [_]  a Small Business Investment Company licensed by the U.S. Small
          Business Administration under Section 301(c) or (d) of the Small
          Business Investment Act of 1958;

     [_]  an investment company registered under the Investment Company Act of
          1940 or a business development company as defined in Section 2(a)(48)
          of that Act;

     [_]  a trust not organized to make this particular investment, with total
          assets in excess of $5,000,000 whose purchase is directed by a
          sophisticated person as described in Rule 506(b)(2)(ii) of the
          Securities Act of 1933 and who completed item 4 below of this
          questionnaire;

     [_]  a bank as defined in Section 3(a)(2) or a savings and loan
          association or other institution defined in Section 3(a)(5)(A) of the
          Securities Act of 1933 acting in either an individual or fiduciary
          capacity;

     [_]  an insurance company as defined in Section 2(13) of the Securities
          Act of 1933;

     [_]  an employee benefit plan within the meaning of Title I of the
          Employee Retirement Income Security Act of 1974 (i) whose investment
          decision is made by a fiduciary which is either a bank, savings and
          loan association, insurance company, or registered investment advisor,
          or (ii) whose total assets exceed $5,000,000, or (iii) if a
          self-directed plan, whose investment decisions are made solely by a
          person who is an accredited investor and who completed Part I of this
          questionnaire;

     [_]  a charitable, religious, educational or other organization described
          in Section 501(c)(3) of the Internal Revenue Code, not formed for the
          purpose of this investment, with total assets in excess of $5,000,000;

     [_]  an entity not located in the U.S. none of whose equity owners are
          U.S. citizens or U.S. residents;

     [_]  a broker or dealer registered under Section 15 of the Securities
          Exchange Act of 1934;

     [_]  a plan having assets exceeding $5,000,000 established and maintained
          by a government agency for its employees; or

     [_]  Other.  Describe: __________________________________________
          ____________________________________________________________
          ____________________________________________________________

                                      I-7



4.  INVESTMENT EXPERIENCE
    ---------------------

         Please provide general information concerning the business, financial
         and investment experience of the entity and investment manager of such
         entity.

         -------------------------------------------------------------

         -------------------------------------------------------------

         -------------------------------------------------------------







                                 III. SIGNATURE
                                      ---------

     The above information is true and correct. The undersigned recognizes that
     the Company and its counsel are relying on the truth and accuracy of such
     information in reliance on the exemption contained in Subsection 4(2) of
     the Securities Act of 1933, as amended, and Regulation D promulgated
     thereunder. The undersigned agrees to notify the Company promptly of any
     changes in the foregoing information which may occur prior to the
     investment.

         Executed  at ___________________, on  _________________, 2002.


                                                     ___________________________
                                                     (Signature)

         ____________________________________
                                                     (Title if for Entity)

                                      I-9



                                                                      Appendix I


                                 TRIMERIS, INC.
                      REGISTRATION STATEMENT QUESTIONNAIRE
                      -------------------------------------

                  In connection with the preparation of the Registration
Statement, please provide us with the following information:

                  1. Pursuant to the "Selling Shareholder" section of the
Registration Statement, please state your or your organization's name exactly as
it should appear in the Registration Statement:

                  ___________________________________________

                  2. Please provide the number of shares of Trimeris, Inc. that
you or your organization will beneficially own immediately after Closing,
including those Shares purchased by you or your organization pursuant to this
Purchase Agreement and those shares purchased by you or your organization
through other transactions:

                  ___________________________________________

                  3.       Have you or your organization had any position,
office or other material relationship within the past three years with the
Company or its affiliates?

                  _____ Yes                 _____ No

                  If yes, please indicate the nature of any such relationships
below:

                  ______________________________________________________________

                  ______________________________________________________________

                  4. Are you (i) an NASD Member (see definition), (ii) a
Controlling (see definition) shareholder of an NASD Member, (iii) a Person
Associated with a Member of the NASD (see definition), or (iv) an Underwriter or
a Related Person (see definition) with respect to the proposed offering; or (b)
do you own any shares or other securities of any NASD Member not purchased in
the open market; or (c) have you made any outstanding subordinated loans to any
NASD Member?

                  Answer:  [___] Yes    [___] No     If "yes," please describe
below

                  ______________________________________________________________

                  ______________________________________________________________

                  ______________________________________________________________

                                      I-10





         NASD Member.  The term "NASD member" means either any broker or dealer
         -----------
admitted to membership in the National Association of Securities Dealers, Inc.
("NASD").  (NASD Manual, By-laws Article I, Definitions)

         Control. The term "control" (including the terms "controlling,"
         -------
"controlled by" and "under common control with") means the possession, direct or
indirect, of the power, either individually or with others, to direct or cause
the direction of the management and policies of a person, whether through the
ownership of voting securities, by contract, or otherwise. (Rule 405 under the
Securities Act of 1933, as amended)

         Person Associated with a member of the NASD. The term "person
         -------------------------------------------
associated with a member of the NASD" means every sole proprietor, partner,
officer, director, branch manager or executive representative of any NASD
Member, or any natural person occupying a similar status or performing similar
functions, or any natural person engaged in the investment banking or securities
business who is directly or indirectly controlling or controlled by a NASD
Member, whether or not such person is registered or exempt from registration
with the NASD pursuant to its bylaws. (NASD Manual, By-laws Article I,
Definitions)

         Underwriter or a Related Person. The term "underwriter or a related
         -------------------------------
person" means, with respect to a proposed offering, underwriters, underwriters'
counsel, financial consultants and advisors, finders, members of the selling or
distribution group, and any and all other persons associated with or related to
any of such persons. (NASD Interpretation)

                                      I-11



                                                                     APPENDIX II

Attention:

                   PURCHASER'S CERTIFICATE OF SUBSEQUENT SALE
                   ------------------------------------------

            The undersigned, [an officer of, or other person duly authorized by]

____________________________________________________________________

            [fill in official name of individual or institution]

hereby certifies that he/she [said institution] is the Purchaser of

the shares evidenced by the attached certificate, and as such,

sold such shares on __________________ in accordance with

                      [date]

Registration Statement number _____________________________________

                      [fill in the number of or otherwise identify Registration
Statement]

and the requirement of delivering a current prospectus by the Company has been

complied with in connection with such sale.


Print or Type:

          Name of Purchaser
            (Individual or
            Institution):        ______________________

          Name of Individual
            Representing
            Purchaser (if an
            Institution):        ______________________

          Title of Individual
            Representing
            Purchaser (if an
            Institution):        ______________________

Signature by:

          Individual Purchaser
            or Individual repre-
            senting Purchaser:   ______________________

                                      II-1