As filed with the Securities and Exchange Commission on July 13, 1998. Registration No. 333-_______ ================================================================================ SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Endogen, Inc. (Exact Name of Registrant as Specified in Its Charter) Massachusetts 04-2789249 (State or Other Jurisdiction of (I.R.S. Employer Identification No.) Incorporation or Organization) 30 Commerce Way Woburn, Massachusetts 01801-1059 (Address of Principal Executive Offices) (Zip Code) ------------------------------------ 1992 Stock Plan (Full Title of the Plan) ------------------------------------ Owen A. Dempsey Chief Executive Officer Endogen, Inc. 30 Commerce Way Woburn, Massachusetts 01801-1059 (781) 937-0890 (Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent for Service) ------------------------------------ Copy to: William J. Schnoor, Jr., Esq. Testa, Hurwitz & Thibeault, LLP 125 High Street Boston, MA 02110 (617) 248-7000 CALCULATION OF REGISTRATION FEE ======================================================================================================================= Proposed Maximum Proposed Maximum Title Of Securities Amount To Be Offering Price Per Aggregate Offering Amount Of To Be Registered Registered Share Price Registration Fee - ----------------------------------------------------------------------------------------------------------------------- Common Stock, par value $.01 20,226(1) $4.38(1) $ 88,589.88(1) $ 26.14 Common Stock, par value $.01 7,500(2) $4.00(2) $ 30,000.00(2) $ 8.85 Common Stock, par value $.01 89,750(3) $3.81(3) $341,947.50(3) $100.88 Common Stock, par value $.01 114,025(4) $3.69(4) $420,752.25(4) $124.13 -------- ----------- ------- TOTAL: 231,501 $881,289.63 $260.00 ======== =========== ======= ======================================================================================================================= (1) All such shares are issuable upon exercise of outstanding options to purchase an aggregate of 20,226 shares at an exercise price of $4.38 per share. Pursuant to Regulation C, Rule 457(h)(1) under the Securities Act of 1933, as amended, the aggregate offering price and fee have been computed upon the basis of the price at which the options may be exercised. (2) All such shares are issuable upon exercise of outstanding options to purchase an aggregate of 7,500 shares at an exercise price of $4.00 per share. Pursuant to Regulation C, Rule 457(h)(1) under the Securities Act of 1933, as amended, the aggregate offering price and fee have been computed upon the basis of the price at which the options may be exercised. (3) All such shares are issuable upon exercise of outstanding options to purchase an aggregate of 89,750 shares at an exercise price of $3.81 per share. Pursuant to Regulation C, Rule 457(h)(1) under the Securities Act of 1933, as amended, the aggregate offering price and fee have been computed upon the basis of the price at which the options may be exercised. (4) Pursuant to Regulation C, Rule 457(h)(1) under the Securities Act of 1933, as amended, the price of $3.69 per share, which is the average of the high and low prices of the Common Stock as reported on the Nasdaq SmallCap Market on July 9, 1998, is set forth solely for purposes of calculating the filing fee. This Registration Statement registers additional securities of the same class as other securities for which Registration Statement No. 33-64440 on Form S-8 as filed with the Securities and Exchange Commission (the "SEC") on June 15, 1993 and Registration Statement No. 33-77576 on Form S-8 as filed with the SEC on April 11, 1994, relating to the Endogen, Inc. 1992 Stock Plan are effective. Pursuant to General Instruction E, the contents of the above-listed Registration Statements are hereby incorporated by reference. PART II INFORMATION REQUIRED IN THE REGISTRATION STATEMENT Item 8. Exhibits -------- Exhibit No. Description of Exhibits ----------- ----------------------- 4.1 1992 Stock Plan of the Registrant, as amended November 6, 1997 4.2 Form of Non-Qualified Stock Option Agreement under the 1992 Stock Plan of the Registrant 4.3 Form of Incentive Stock Option Agreement under the 1992 Stock Plan of the Registrant 4.4 By-Laws, as amended on September 5, 1997 (filed as Exhibit 3.1 to the Company's Quarterly Report on Form 10-QSB for the quarter ended August 31, 1997 and incorporated herein by reference) 4.5 Restated Articles of Organization, as amended (filed as Exhibit 3.1 to the Company's Quarterly Report on Form 10-QSB for the quarter ended November 30, 1996 and incorporated herein by reference) 5.1 Opinion of Testa, Hurwitz & Thibeault, LLP 23.1 Consent of PricewaterhouseCoopers LLP 23.2 Consent of Testa, Hurwitz & Thibeault, LLP (included in Exhibit 5.1) 24.1 Power of Attorney (contained in Page 2 of this Registration Statement) SIGNATURES Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Woburn, Commonwealth of Massachusetts, on June 30, 1998. ENDOGEN, INC. /s/ Owen A. Dempsey ------------------------------------ Owen A. Dempsey Director and Chief Executive Officer POWER OF ATTORNEY AND SIGNATURES We, the undersigned officers and directors of Endogen, Inc., hereby severally constitute and appoint Owen A. Dempsey and Avery W. Catlin, and each of them singly, our true and lawful attorneys, with full power to them and each of them singly, to sign for us in our names in the capacities indicated below, all pre-effective and post-effective amendments to this registration statement, and generally to do all things in our names and on our behalf in such capacities to enable Endogen, Inc. to comply with the provisions of the Securities Act of 1933, as amended, and all requirements of the Securities and Exchange Commission. Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed by the following persons in the capacities and on the dates indicated. Signature Title Date - --------- ----- ---- /s/ Owen A. Dempsey Director and Chief Executive Officer (Principal June 30, 1998 - ------------------------------------ Executive Officer) Owen A. Dempsey /s/ Avery W. Catlin Vice President, Finance, Chief Financial Officer, June 30, 1998 - ------------------------------------ Treasurer and Clerk (Principal Financial and Avery W. Catlin Accounting Officer) /s/ Wallace G. Dempsey Director June 30, 1998 - ------------------------------------ Wallace G. Dempsey /s/ Hayden H. Harris Director June 30, 1998 - ------------------------------------ Hayden H. Harris /s/ Wolfgang Woloszcuzuk Director June 30, 1998 - ------------------------------------ Wolfgang Woloszczuk /s/ Irwin Gruverman Director June 30, 1998 - ------------------------------------ Irwin Gruverman EXHIBIT INDEX ------------- Exhibit No. Description of Exhibit - ----------- ---------------------- 4.1 1992 Stock Plan of the Registrant, as amended November 6, 1997 4.2 Form of Non-Qualified Stock Option Agreement under the 1992 Stock Plan of the Registrant 4.3 Form of Incentive Stock Option Agreement under the 1992 Stock Plan of the Registrant 4.4 By-Laws, as amended on September 5, 1997 (filed as Exhibit 3.1 to the Company's Quarterly Report on Form 10-QSB for the quarter ended August 31, 1997 and incorporated herein by reference) 4.5 Restated Articles of Organization, as amended (filed as Exhibit 3.1 to the Company's Quarterly Report on Form 10-QSB for the quarter ended November 30, 1996 and incorporated herein by reference) 5.1 Opinion of Testa, Hurwitz & Thibeault, LLP 23.1 Consent of PricewaterhouseCoopers LLP 23.2 Consent of Testa, Hurwitz & Thibeault, LLP (included in Exhibit 5.1) 24.1 Power of Attorney (contained in Page 2 of this Registration Statement)