1 ================================================================================ U.S. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 -------------------- FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: September 18, 1997 RIBOZYME PHARMACEUTICALS, INC. (Exact Name of Small Business Issuer as Specified in Its Charter) Delaware Commission file number 0-27914 34-1697351 -------- ---------- (State of incorporation) (I.R.S. Employer Identification No.) 2950 Wilderness Place Boulder, Colorado 80301 (Address of principal executive offices) Registrant's telephone number: (303) 449-6500 -------------------- 2 ITEM 5. Other Events On April 9, 1997, Ribozyme Pharmaceuticals, Inc. ("RPI") entered into a research collaboration with Schering AG, Germany ("Schering"), focusing on the use of ribozymes for therapeutic target validation, as well as the development of ribozymes as therapeutic agents. The collaboration will utilize the special selectivity of ribozymes to validate new molecular therapeutic targets, and to discover new therapeutic agents based on those targets. RPI will provide its expertise in ribozyme design, synthesis and delivery, and Berlex Laboratories, Inc., a U.S. subsidiary of Schering, will provide candidate targets, cell culture screens, animal models and development and commercialization expertise to the collaboration. It is anticipated that hundreds of potential targets will be examined over a five year period, and Berlex will have options to commercialize products from validated targets. Schering will make an equity investment of up to $5 million over the next year and will separately provide loans of up to $2 million for each of the next five years. These loans are convertible into equity at the option of Schering under certain circumstances. In addition, Schering will make research payments of $2 million a year for the next five years and RPI may earn success fees and product development milestones, and will manufacture synthetic ribozyme products and receive royalties on both ribozyme and non-ribozyme products resulting from the collaboration. All such payments are subject to certain restrictions, including receipt of certain third party consents. The research collaboration may be terminated at Schering's option after April 9, 1998. 2 3 SIGNATURES In accordance with the requirements of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized. RIBOZYME PHARMACEUTICALS, INC. Dated: September 18, 1997 By: /s/ Lawrence E. Bullock ------------------------------- Lawrence E. Bullock Vice President and Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer) 4 EXHIBIT INDEX Number - ------ 1.1* Research, License, Supply and Royalty Agreement Between Schering Aktiengesellschaft and the Company, dated April 9, 1997. 1.2* Purchase Agreement dated as of April 9, 1997 among the Company, Schering Berlin Venture Corporation and Schering Aktiengesellschaft. * The confidential portions ( [ ] ) of these exhibits have been omitted pursuant to regulation 240.25b-2(b) of the Securities Exchange Act of 1934, and have been filed separately with the Commission.