Exhibit 16 November 6, 2000 Office of the Chief Accountant Securities and Exchange Commission 450 Fifth Street, N.W. Washington, DC 20549 Dear Sir/Madam: We have read the first two paragraphs of Item 4 included in the Form 8-K dated October 31, 2000 of Covalent Group, Inc. to be filed with the Securities and Exchange Commission on November 7, 2000 and are in agreement with the statements contained therein. Very truly yours, /s/ ARTHUR ANDERSEN LLP ARTHUR ANDERSEN LLP cc: William K. Robinson Chief Financial Officer Covalent Group, Inc.